Teresa H. Evering, Kara W. Chew, Mark J. Giganti, Carlee Moser, Mauricio Pinilla, David A. Wohl, Judith S. Currier, Joseph J. Eron, Arzhang Cyrus Javan, Rachel Bender Ignacio, David M. Margolis, Qing Zhu, Ji Ma, Lijie Zhong, Yan Li, Ulises D’Andrea Nores, Keila Hoover, Bharat Mocherla, Manish C. Choudhary, Rinki Deo, Justin Ritz, William A. Fischer, Courtney V. Fletcher, Jonathan Z. Li, Michael D. Hughes, Davey M. Smith, Eric S. Daar, Teresa H. Evering, Kara W. Chew, Mark J. Giganti, Carlee Moser, David A. Wohl, Judith S. Currier, Joseph J. Eron, Arzhang Cyrus Javan, Rachel Bender Ignacio, David M. Margolis, Ulises D’Andrea Nores, Keila Hoover, Bharat Mocherla, Manish C. Choudhary, Justin Ritz, William A. Fischer, Courtney V. Fletcher, Jonathan Z. Li, Michael D. Hughes, Davey M. Smith, Eric S. Daar, Lara Hosey, Jhoanna Roa, Nilam Patel, Kelly Colsh, Irene Rwakazina, Justine Beck, Scott F. Sieg, Sandra Wagner Cardoso, Katya Corado, Prasanna Jagannathan, Nikolaus Jilg, Alan S. Perelson, Sandy Pillay, Cynthia Riviere, Upinder Singh, Babafemi Taiwo, Joan Gottesman, Matthew Newell, Susan Pedersen, Joan Dragavon, Cheryl Jennings, Brian Greenfelder, William Murtaugh, Jan Kosmyna, Morgan Gapara, Akbar Shahkolahi, Verónica Lacal, D. Salusso, Sebastian Nuñez, Marcelo Rodrigo Rodriguez, Luciana Laborde, Marcelo Papasidero, Luis Wehbe, Mariana González, F. Fernandez Voena, T. Alvarez, Amaru Lopez, V Huhn, Pablo Dieser, Fernando Bordese, Marisa Mussi, Rodrigo de Carvalho Santana, Adriana Aparecida Tiraboschi Bárbaro, Breno Santos, Rita de Cássia Alves Lira, Andre Luiz Machado da Silva, Maria Pia Diniz Ribeiro, Nathália Soliva, Eduardo Vasconcellos, Jorge Eurico Ribeiro, Miriam Amaral Enéas, Jorge Pinto, Júlia Fonseca de Morais Caporali, Flávia Gomes Faleiro Ferreira, Norma E. Rivera-Martínez, Víctor Casildo Bohórquez López, Melchor Victor Frias, Krystle Fetalvero, Alyxzza Maranan, Jennifer Rosa, Thomas Frederic Coetzer, Sr Maureen Mohata, Umesh Lalloo, Penelope Madlala, Larisha Pillay-Ramaya, Jaclyn Bennet, Noluthando Mwelase, Nokuphiwa Mbhele, Frederick Petrick, Leonard Joubert, Sr Rose Mbali, Natasha Joseph, Mmatsie Manentsa, Eugene van der Walt, Mduduzi Masilela, Zinhle Zwane, Tendai Chiperera, Lerato Mohapi, Suri Moonsamy, Usha Singh, Kirsten McHarry, Elizma Snyman, Pieter Lennox, James Craig Innes, Oteng Letlape, Olebogeng Jonkane, William Brumskine, Tania Adonis, Ni Ni Sein, Modulakgotla Sebe, Yacoob Vahed, Nazreen Jeewa Hussen, Ismail Mitha, Vasundhara Cheekati, Purna Cheekati, Christie Lummus, Samuel H Idarraga, Andrew Kim, David Pham, Wei-Hsin Kao, Michael M. Pfeffer, Miriam Batule Dominguez, Francisco Patron, Luz Guzman, E Juncadella Ferrer, Anju Malik, Anna Bryan, Melanie Arnold, Idania Fernandez, Cinzia Karpf, A. Bazzoni Ruiz, David Taylor, Eric Folkens, Jennifer Manne‐Goehler, Sigal Yawetz, Cheryl Keenan, Emeka Eziri, Carl J. Fichtenbaum, Jenifer Baer, Sarah Trentman, Robert S. Call, Leroy Vaughan, Aaron P. Milstone, Jamie Alex Slandzicki, Jessica Wallan, Clinton Guillory, Nancy Andrews, L E Hughes, Jonathan Berardi, Celine Arar, Randall Quinn, Jorge P. Amaya, Marissa Gomez-Martinez, Luis Cantu, Monica M. Betancourt-Garcia, Nwora Lance Okeke, Charles M. Burns, Fadi Haddad, Victoria Haddad, Jeanne-Elyse Cedeno, Lisbel Gonzalez, L. Pestana, Augusto Focil, Griselda Rosas, Susana Moyano, Yaneicy Gonzalez Rojas, Ahmad Aswad, Yevgeniy Bukhman, Manish Kumar Jain, Eugene Bukhman, Humam Farah, R. Michael McClain, Sadia Shaik, Timothy Hatlen, Deepa Gotur, Joseph Surber, Jeffrey S. Kingsley, April Pixler, Alex Zopo, Jack Herman, Craig Herman, Ramón Fernández de León, Boris Nikolov, Laurie Welton, Barbara Bromberg, Kelly Christina, Fernando Gonzalez Vergara, Ana Isabel González, Noemí González, Michael A. Gelman, Olga Andriunas, Zarema Jagizarov, Jan Westerman, David O. Davis, Donna Sherer, Kelly E. Dooley, Becky Becker, Adaliah Wilkins, J. Pérez, Eloy Roman, Heriberto Fernandéz, Kelly von Beck, V. Calatayud Maldonado, Jennifer Veltman, Rajesh T. Gandhi, Katrina Shea, M. Gustave Planchon, Laura Herpel, Kaushlendra K. Tripathi, Donald C. Day, John Pullman, Erin Williams-Leber, Misty Johnson, Michelle T. Hecker, Ann Avery, George W. Monlux, Elizabeth Juneja, Arthur Wernick, Karelia Ruiz, Maureen Hernández, Y. E. Ramírez Pérez, Claudia Hawkins, Baiba Berzins, Carlos Malvestutto, Heather Harber, Robyn Cicarella, Edwin DeJesus, Charlotte-Paige Rolle, Almena Free, Sallie D. Pulliam, D. Weinstein, Rosa Suárez, Ezequiel Socorro, Estefania Socorro, Gene Neytman, Jack Herman, Craig Herman, R. Blaine Easley, Mariam Aziz, J. A. Swiatek, Avish Nagpal, Breanna Kompelien, K McEvoy, Susan E. Hoover, A Lutz, Jessica Just, Manuel Hernandez, Yanly B. Victoria, Gabriel Rodríguez, Divya Pathak, Joshua J. Ordway, Megan Heffner, Patrick Weston, Khalilah Weston, Madhu Choudhary, Jennifer Sullivano, Olayemi Osiyemi, Myriam Izquierdo, Odelsey Torna, Brian M. Clemency, Renoj Varughese, Joshua J. Lynch, Aleen Khodabakhshian, Samantha Fortier, Christopher J. Coyne, A. Cronin, Constance A. Benson, Steven Hendrickx,
Background: Development of safe and effective SARS-CoV-2 therapeutics is a high priority. Amubarvimab and romlusevimab are noncompeting anti–SARS-CoV-2 monoclonal antibodies with an extended half-life. Objective: To assess the safety and efficacy of amubarvimab plus romlusevimab. Design: Randomized, placebo-controlled, phase 2 and 3 platform trial. (ClinicalTrials.gov: NCT04518410) Setting: Nonhospitalized patients with COVID-19 in the United States, Brazil, South Africa, Mexico, Argentina, and the ...
American College of Physicians
Produção Nacional
Revisado por pares
Shahin Lockman, Sean S. Brummel, Lauren Ziemba, Lynda Stranix‐Chibanda, Katie McCarthy, Anne Coletti, Patrick Jean‐Philippe, Ben Johnston, Chelsea Krotje, Lee Fairlie, Risa M. Hoffman, Paul E. Sax, Sikhulile Moyo, Nahida Chakhtoura, Jeffrey S. A. Stringer, Gaerolwe Masheto, Violet Korutaro, Haseena Cassim, Blandina T. Mmbaga, Esaú João, Sherika Hanley, Lynette Purdue, Lewis B. Holmes, Jeremiah D. Momper, Roger Shapiro, Navdeep Thoofer, James F. Rooney, Lisa M. Frenkel, K. Rivet Amico, Lameck Chinula, Judith S. Currier, Brookie M. Best, Cheryl Blanchette, Renee Browning, Yao Cheng, Andee Fox, Nagawa Jaliaah, Kevin Knowles, Mark Mirochnick, William Murtaugh, Emmanuel Patras, Mauricio Pinilla, Jean van Wyk, Frances Whalen,
Background Antiretroviral therapy (ART) during pregnancy is important for both maternal health and prevention of perinatal HIV-1 transmission; however adequate data on the safety and efficacy of different ART regimens that are likely to be used by pregnant women are scarce. In this trial we compared the safety and efficacy of three antiretroviral regimens started in pregnancy: dolutegravir, emtricitabine, and tenofovir alafenamide fumarate; dolutegravir, emtricitabine, and tenofovir disoproxil fumarate; ...
Tópico(s): HIV Research and Treatment
2021 - Elsevier BV | The Lancet
Gerhard Theron, Sean S. Brummel, Lee Fairlie, Mauricio Pinilla, Katie McCarthy, Maxensia Owor, Lameck Chinula, Bonus Makanani, Avy Violari, Dhayendre Moodley, Nahida Chakhtoura, Renee Browning, Risa M. Hoffman, Mary Glenn Fowler,
Globally, the number of infected women of childbearing age living with human immunodeficiency virus (HIV) and conceiving on antiretroviral therapy (ART) is increasing. Evidence of ART safety at conception and during pregnancy and adverse pregnancy outcomes remains conflicting. The Promoting Maternal and Infant Survival Everywhere (PROMISE) 1077 breastfeeding (BF) and formula feeding (FF) international multisite trials provide an opportunity to examine the impact of ART at conception on pregnancy outcomes ...
Tópico(s): HIV-related health complications and treatments
2020 - Oxford University Press | Clinical Infectious Diseases
Kristina M. Brooks, Jeremiah D. Momper, Mauricio Pinilla, Alice Stek, Emily Barr, Adriana Weinberg, Jaime G. Deville, Irma Febo, Mikhaela Cielo, Kathleen George, Kayla Denson, Kittipong Rungruengthanakit, David E. Shapiro, Elizabeth Smith, Nahida Chakhtoura, James F. Rooney, Richard Haubrich, Rowena Espina, Edmund V. Capparelli, Mark Mirochnick, Brookie M. Best,
Objective: To evaluate the pharmacokinetics of tenofovir alafenamide (TAF) 10 mg with cobicistat and 25 mg without boosting in pregnant and postpartum women with HIV and to characterize TAF placental transfer and infant washout pharmacokinetics. Design: Open-label, multicenter phase IV prospective study of TAF pharmacokinetics during pregnancy, postpartum, delivery, and infant washout. Methods: Pregnant women receiving TAF 10 mg with cobicistat or TAF 25 mg without boosting as part of clinical care ...
Tópico(s): HIV Research and Treatment
2020 - Lippincott Williams & Wilkins | AIDS
Marina Muñoz, Dora Ríos-Chaparro, Giovanny Herrera, Sara Cecilia Soto‐De León, Claudia Birchenall, Darío Pinilla, Juan Mauricio Pardo Oviedo, Diego Fernando Josa, Manuel A. Patarroyo, Juan David Ramírez,
Clostridium difficile (CD) produces antibiotic associated diarrhea and leads to a broad range of diseases. The source of CD infection (CDI) acquisition and toxigenic profile are factors determining the impact of CD. This study aimed at detecting healthcare facility onset- (HCFO) and community-onset (CO) CDI and describing their toxigenic profiles in Bogotá, Colombia. A total of 217 fecal samples from patients suffering diarrhea were simultaneously submitted to two CDI detection strategies: (i) in vitro ...
Tópico(s): Microscopic Colitis
2018 - Frontiers Media | Frontiers in Microbiology
Mauricio Pinilla, Francisco Martel González, C López-Cortijo, B Arellano, J. M. Herrero, Almudena Trinidad, Jorge E. López de Vergara,
Management of patients with carcinoma of the larynx should systematically include an appropriate treatment of lymph nodes according to the TNM stage. One of the most controversial points of the treatment in these patients is the management of the clinically negative neck (N(0)). A retrospective study of 295 patients with laryngeal carcinoma and N(0) neck undergoing treatment in our centre between 1983 and 1993 is presented. We observed a significant decrease in the survival of clinically N(0) patients ...
Tópico(s): Cancer Diagnosis and Treatment
2003 - Cambridge University Press | The Journal of Laryngology & Otology
Jorge Alberto Cortés, Diego Perdomo, Renán Morales, Carlos Álvarez, Sonia Isabel Cuervo, Aura Lucía Leal, Julio César Gómez, Patricia Reyes, Análida Elizabeth Pinilla, Edgar Mauricio Bueno Castellanos, Wilfredo Donoso Donoso,
<p class="p1"><span class="s1">Mediante un proceso de adaptación de guías de práctica clínica se seleccionaron y evaluaron guías de infección de vías urinarias en mujeres premenopáusicas no embarazadas; se identificaron 3 de alta calidad. Con base en las evidencias y las recomendaciones aportadas por estas guías, se realizó un consenso para realizar recomendaciones para personal de salud —médicos, personal de laboratorio y enfermeros— sobre el diagnóstico de las infecciones urinarias — ...
Tópico(s): Pelvic floor disorders treatments
2015 - National University of Colombia | Revista de la Facultad de Medicina
Produção Nacional
Revisado por pares
Risa M. Hoffman, Sean S. Brummel, Lauren Ziemba, Lameck Chinula, Katie McCarthy, Lee Fairlie, Patrick Jean‐Philippe, Nahida Chakhtoura, Ben Johnston, Chelsea Krotje, Teacler Nematadzira, Frances Nakayiwa, Victoria Ndyanabangi, Sherika Hanley, Gerhard Theron, Avy Violari, Esaú João, Mário Dias Corrêa Júnior, Cristina Barroso Hofer, Oranich Navanukroh, Linda Aurpibul, Neetal Nevrekar, Rebecca Zash, Roger Shapiro, Jeffrey S. A. Stringer, Judith S. Currier, Paul E. Sax, Shahin Lockman, Sharon Nachman, James McIntyre, David P. Harrington, Catherine Hill, Steven Joffe, Alwyn Mwinga, Andrew Nunn, Merlin L. Robb, Haroon Saloojee, Merlin L. Robb, Jonathan Kimmelman, Graeme Meintjes, Barbara E. Murray, Stuart C. Ray, Haroon Saloojee, Anastasios A. Tsiatis, Paul A. Volberding, David V. Glidden, Valéria C. Rolla, Nicola Piper, Karin L. Klingman, Debika Bhattacharya, Lynne Mofenson, Scott McCallister, Jean van Wyk, Mark Mirochnick, Brookie M. Best, Kevin Robertson, Cheryl Blanchette, Nagawa Jaliaah, Andi Fox, Frances Whalen, Kevin Knowles, William Murtaugh, Mauricio Pinilla, Yao Cheng, Emmanuel Patras, Jim Rooney, Rich Clark, Scott McCallister, Jean van Wyck, Anne Coletti, Lynette Purdue, Lisa M. Frenkel, K. Rivet Amico, Lewis B. Holmes, Gaerolwe Masheto, Sikhulile Moyo, Jeremiah D. Momper, Lynda Stranix‐Chibanda, Kevin Knowles, William Murtaugh, Frances Whalen, Gaborone Molepolole, Ponego Ponatshego, Lesedi Tirelo, Dip Nursing, Boitshepo J Seme, Dip Nursing, Georginah O Modise, Dip Nursingo S Raesi, Marian E Budu, Moakanyi Ramogodiri, Ricardo Hugo de Oliveira, Thalita Fernandes de Abreu, Lorena Macedo Pestanha, Leon Claude Sidi, Trevon Fuller, Maria Letícia Santos Cruz, Jorge Pinto, Flãvia Ferreira, Juliana Ribeiro Romeiro, José Henrique Pilotto, Luis Eduardo Barros Costa Fernandes, Luíz Felipe Pinho Moreira, Ivete Martins Gomes, Shilpa Naik, Vidya Mave, Aarti Kinikar, Lee Fairlie, Elizea Horne, Faeezah Patel, Hamisha Soma-Kasiram, Haseena Cassim, Sisinyana Ruth Mathiba, Mandisa Nyati, Jeanne de Jager, Magdel Rossouw, Lindie Rossouw, Alicia Catherine Desmondarm, Rosemary Gazu, Dip Nursing, Vani Govender, Amphan Chalermchockcharoenkit, Manopchai Thamkhantho, Peerawong Werarak, Supattra Rungmaitree, Jullapong Achalapong, Lukkana Sitiritkawin, Tim R. Cressey, Pra-ornsuda Sukrakanchana, Fuanglada Tongprasert, Chintana Khamrong, Sopida Kiattivej, Deo Wabwire, Enid Kabugo, Joel Maena, Beatrice Nagaddya, Dip Nus Mid, Rogers Sekabira, Justus Ashaba, Charles D. Mitchell, Adriana Drada, Grace A Alvarez, Gwendolyn B. Scott, Mobeen H. Rathore, Saniyyah MahmoudiN, Adnan Shabbir, Nizar Maraqa, Patricia Mandima, Mercy Mutambanengwe, Bpharm Hons, Suzen Maonera, Vongai Chanaiwa, Hons Clin Epi, Taguma Allen Matubu, Kevin Tamirepi, Sukunena Maturure, Tsungai Mhembere, Tichaona Vhembo, Tinashe Chidemo,
Abstract Background We evaluated associations between antepartum weight change and adverse pregnancy outcomes and between antiretroviral therapy (ART) regimens and week 50 postpartum body mass index in IMPAACT 2010. Methods Women with human immunodeficiency virus (HIV)-1 in 9 countries were randomized 1:1:1 at 14–28 weeks’ gestational age (GA) to start dolutegravir (DTG) + emtricitabine (FTC)/tenofovir alafenamide fumarate (TAF) versus DTG + FTC/tenofovir disoproxil fumarate (TDF) versus efavirenz (EFV)/FTC/ ...
Tópico(s): HIV/AIDS Research and Interventions
2024 - Oxford University Press | Clinical Infectious Diseases
Marina Muñoz, Daniel Restrepo-Montoya, Nitin Kumar, Gregorio Iraola, Milena Camargo, Diana Díaz-Arévalo, Nelly S. Roa, Mayra Téllez, Giovanny Herrera, Dora Ríos-Chaparro, Claudia Birchenall, Darío Pinilla, Juan Mauricio Pardo Oviedo, Giovanni Rodríguez-Leguizamón, Diego Fernando Josa, Trevor D. Lawley, Manuel A. Patarroyo, Juan David Ramírez,
Abstract Clostridium difficile , the causal agent of antibiotic-associated diarrhea, has a complex epidemiology poorly studied in Latin America. We performed a robust genomic and phenotypic profiling of 53 C . difficile clinical isolates established from diarrheal samples from either intrahospital (IH) or community (CO) populations in central Colombia. In vitro tests were conducted to evaluate the cytopathic effect, the minimum inhibitory concentration of ten antimicrobial agents, the sporulation efficiency ...
Tópico(s): Helicobacter pylori-related gastroenterology studies
2019 - Nature Portfolio | Scientific Reports
C. González, Francisco Martel González, A. Trinidad, Andrés Ibáñez, Mauricio Pinilla, Antonio Martínez Ruíz-Coello, Antonio Rodríguez Valiente, C López-Cortijo,
Tópico(s): Glaucoma and retinal disorders
2010 - Springer Science+Business Media | European Archives of Oto-Rhino-Laryngology
V Margarita Chiang, Portocarrero Núñez, María José Pinilla Martín, Carlos Mauricio Salazar Botello,
El compromiso de los trabajadores y el clima organizacional son relevantes en el comportamiento de las personas. Se analiza la relacion entre ambos constructos segun genero y edad. La muestra son 64 trabajadores. Se realiza un estudio empirico transversal aplicando cuestionarios para compromiso del trabajador de Meyer y Allen (1991) y clima organizacional de Chiang et al. (2008), ambos validados. Los resultados muestran que en compromiso y clima organizacional, no hay diferencias importantes entre ...
Tópico(s): Organizational Management and Innovation
2010 - | Panorama socioeconómico
Dileep N. Lobo, C López-Cortijo, Roberto de la Fuente, D. Laguna, Mauricio Pinilla, Carmen Galve Górriz,
Se presenta una serie de 1.093 pacientes intervenidos a lo largo de 10 años de cirugía endoscópica por patología nasosinusal en un hospital de tercer nivel. Se describe la técnica empleada y se analizan los resultados a largo plazo, así como las complicaciones menores y mayores, en especial las fístulas de L.C.R. y sus causas We present a serie of 1,093 patients that underwent, along 10 years, endoscopic surgery due to paranasal sinus pathology in a third level hospital. The technique used is described, ...
Tópico(s): Pituitary Gland Disorders and Treatments
2003 - Elsevier BV | Acta Otorrinolaringológica Española
Produção Nacional
Revisado por pares
Fabíola Ayres Cacciatore, Caroline Maders, Bibiana Alexandre, Cristian Mauricio Barreto Pinilla, Adriano Brandelli, Patrícia da Silva Malheiros,
Carvacrol is a natural antimicrobial with excellent antimicrobial properties against several foodborne pathogens. Encapsulation can increase carvacrol stability and solubility, and mask its pronounced odor. Mucilages have been studied as wall material for nanoparticles due to their high retention capacity of bioactive compounds and ease of chemical modifications to improve their stability. In this study, 1.67 mg/mL of carvacrol encapsulated into chia mucilage nanoparticles (CMNP) and flaxseed mucilage ...
Tópico(s): Microencapsulation and Drying Processes
2022 - Elsevier BV | Food Microbiology
Produção Nacional
Revisado por pares
Karina Oliveira Lima, Cristian Mauricio Barreto Pinilla, Ailén Alemán, M.E. López‐Caballero, M.C. Gómez‐Guillén, P. Montero, Carlos Prentice,
In this study, chitosan nanoparticles (CNPs) were prepared by the ionic gelation technique with tripolyphosphate (TPP), and the effect of CNP composition and physicochemical characteristics were evaluated. After the synthesis optimization, CNPs were used as carriers for a fish protein hydrolysate (FPH) with bioactive properties (CNPH). The physicochemical characteristics, antioxidant capacity and antimicrobial, antihypertensive and emulsifier properties of unloaded and loaded CNPs in a food system model ...
Tópico(s): Proteins in Food Systems
2021 - Multidisciplinary Digital Publishing Institute | Polymers
Produção Nacional
Revisado por pares
Cristian Mauricio Barreto Pinilla, Nathalie Almeida Lopes, Adriano Brandelli,
Encapsulation can be a suitable strategy to protect natural antimicrobial substances against some harsh conditions of processing and storage and to provide efficient formulations for antimicrobial delivery. Lipid-based nanostructures, including liposomes, solid lipid nanoparticles (SLNs), and nanostructured lipid nanocarriers (NLCs), are valuable systems for the delivery and controlled release of natural antimicrobial substances. These nanostructures have been used as carriers for bacteriocins and ...
Tópico(s): Advanced Drug Delivery Systems
2021 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Nathalie Almeida Lopes, Omar Mertins, Cristian Mauricio Barreto Pinilla, Adriano Brandelli,
Liposomes modified with biomolecules can present better stability and specific structural characteristics, representing a profitable alternative to conventional liposomes. In this study, liposomes formulations containing pectin (PT) or polygalacturonic acid (PA) were prepared by the thin-film hydration method and reverse phase evaporation method for nisin (Nis) encapsulation. Liposomes free from nisin were studied as reference. Structural characteristics of the formulations were investigated by differential ...
Tópico(s): Surfactants and Colloidal Systems
2020 - Elsevier BV | Food Hydrocolloids
Produção Nacional
Revisado por pares
Cristian Mauricio Barreto Pinilla, Adriano Brandelli, M.E. López‐Caballero, P. Montero, M.C. Gómez‐Guillén,
• Interactions of phosphatidylcholine liposomes with surimi protein were investigated. • FTIR indicates that liposomes induce denaturation and aggregation of surimi protein. • Exposure of tyrosine residues revealed by intrinsic fluorescence analysis of protein. • Increased size and modified surface charge of liposomes interacting with surimi. • The interactions were influenced by the purification degree of phosphatidylcholine . The interactions between liposomes and fish myofibrillar protein (surimi ground salted protein, ...
Tópico(s): Silk-based biomaterials and applications
2020 - Elsevier BV | Food Research International
Produção Nacional
Revisado por pares
Cristian Mauricio Barreto Pinilla, Priscilla Magro Reque, Adriano Brandelli,
Tópico(s): Advancements in Transdermal Drug Delivery
2020 - Springer Science+Business Media | Food and Bioprocess Technology
Produção Nacional
Revisado por pares
Cristian Mauricio Barreto Pinilla, Roberta Cruz Silveira Thys, Adriano Brandelli,
Liposomes have gained great interest in the food and pharmaceutical industry as colloidal carriers of bioactive compounds. In this work, liposomes of phosphatidylcholine (PC) and oleic acid (OA) encapsulating garlic extract (GE) were developed to determine its aptitude as antifungal agent in wheat bread. The influence of GE on the properties of liposomes were followed by determination of size, Zeta potential, Fourier transform infrared patterns (FTIR), morphology, differential scanning calorimetry (DSC) ...
Tópico(s): Pineapple and bromelain studies
2019 - Elsevier BV | International Journal of Food Microbiology
Produção Nacional
Revisado por pares
Priscilla Magro Reque, Cristian Mauricio Barreto Pinilla, Gabrielle Victória Gautério, Susana Juliano Kalil, Adriano Brandelli,
Tópico(s): Food composition and properties
2019 - Elsevier BV | Food Research International
Produção Nacional
Revisado por pares
Nathalie Almeida Lopes, Cristian Mauricio Barreto Pinilla, Adriano Brandelli,
Natural antimicrobials are an innovative alternative for food safety and encapsulation can improve their controlled release and stability. In the present work, lysozyme and its combination with nisin were encapsulated into phosphatidylcholine (PC) liposomes coated with pectin or polygalacturonic acid. The mean particle sizes of liposomes encapsulating lysozyme were 92, 116, and 97 nm for PC, PC-pectin and PC-polygalacutronic acid, respectively. Co-encapsulation of lysozyme and nisin resulted in particle ...
Tópico(s): Food Allergy and Anaphylaxis Research
2019 - Elsevier BV | Food Hydrocolloids
Produção Nacional
Revisado por pares
Nathalie Almeida Lopes, Cristian Mauricio Barreto Pinilla, Adriano Brandelli,
Liposome systems can increase the stability of encapsulated compounds, such as the bacteriocin nisin, improving its benefits as antibacterial agent. In this study, nanoliposomes encapsulating nisin were prepared with soy phosphatidylcholine (PC) and pectin or polygalacturonic acid. The efficiency of encapsulation was 87.9% to PC-pectin and 84.0% to PC-polygalacturonic acid nanoliposomes. The liposomes presented a well-defined spherical shape, with sizes ranging from 94 to 160 nm, showing minimal ...
Tópico(s): Microencapsulation and Drying Processes
2017 - Elsevier BV | Food Hydrocolloids
Produção Nacional
Revisado por pares
Cristian Mauricio Barreto Pinilla, Caciano Pelayo Zapata Noreña, Adriano Brandelli,
Phospholipid nanovesicles were developed to improve the stability of garlic (Allium sativum L.) extract. Electron microscopy of liposomes revealed nanometric and spherical-shaped vesicles with a mean particle size of 174.6±17.3nm and polydispersity index of 0.26±0.02. The entrapment efficiency was 47.5±7.3% and the nanoliposomes had a zeta potential of -16.2±5.5mV. The antimicrobial activity of free and encapsulated garlic extract was evaluated against different strains of Listeria spp. in milk at ...
Tópico(s): Food Allergy and Anaphylaxis Research
2016 - Elsevier BV | Food Chemistry
Produção Nacional
Cristian Mauricio Barreto Pinilla, Adriano Brandelli,
Nisin and garlic extract (GE) were co-encapsulated into phosphatidylcholine nanoliposomes. The mean diameter and zeta potential of the nanoparticles were 179 nm and − 27.7 mV, respectively, with an entrapment efficiency of about 82% and 90% for nisin and GE, respectively. The efficiency of free and encapsulated nisin-GE to control the development of Listeria monocytogenes, Salmonella Enteritidis, Escherichia coli and Staphylococcus aureus was assessed over time in whole milk at 37 °C. At such abuse ...
Tópico(s): Pineapple and bromelain studies
2016 - Elsevier BV | Innovative Food Science & Emerging Technologies
Mark J. Giganti, Kara W. Chew, Joseph J. Eron, Jonathan Z. Li, Mauricio Pinilla, Carlee Moser, Arzhang Cyrus Javan, William A. Fischer, Paul Klekotka, David M. Margolis, David A. Wohl, Robert W. Coombs, Eric S. Daar, Davey M. Smith, Judith S. Currier, Michael D. Hughes, Lara Hosey, Jhoanna Roa, Nilam Patel, Alexander L. Greninger, Emily Degli-Angeli, Erin Goecker, Glenda Daza, Socorro Harb, Joan Dragavon, Grace M. Aldrovandi, William Murtaugh, Frontier Science, Marlene Cooper, Howard Gutzman, Kevin Knowles, Rachel Bowman, Bill Erhardt, Lorraine Waring, Diane Hessinger, Stacey Adams,
There is little information regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA as a predictor for clinical outcomes in outpatients with mild-to-moderate coronavirus disease 2019 (COVID-19).
Tópico(s): COVID-19 Clinical Research Studies
2023 - Oxford University Press | The Journal of Infectious Diseases
Mónica Pinilla‐Roncancio, Mauricio Gallardo,
In Latin America, approximately 70 million individuals live with a disability. Although global evidence suggests that people with disabilities are one of the poorest groups and present lower employment rates, the evidence for Latin America is still weak. This article aims to contribute to the literature by estimating and analysing the levels of employment opportunity for persons with disabilities in six countries in Latin America (Chile, Bolivia, Mexico, Peru, Colombia, and Costa Rica). Using household ...
Tópico(s): Labor Law and Work Dynamics
2022 - SAGE Publishing | Global Social Policy
Produção Nacional
Revisado por pares
Maria Elisa Pailliè Jiménez, Cristian Mauricio Barreto Pinilla, Eliseu Rodrigues, Adriano Brandelli,
Pigments synthesised by Chryseobacterium sp. kr6 growing on feather waste were extracted and characterised. The pigment extract was characterised by KOH test, UV-vis, CIELAB colour system, HPLC-DAD-MS, FTIR and its antioxidant capacity was evaluated. A positive bathochromic shift was observed when kr6 colonies or pigment extracts were subjected to alkaline solution (20% KOH) and a λmax at 450 nm was detected for acetone extracts, although no typical fine structure of carotenoids was detected in the ...
Tópico(s): Algal biology and biofuel production
2018 - Taylor & Francis | Natural Product Research
Rafael Ramírez‐Camacho, Mauricio Pinilla, José Ramón García‐Berrocal,
Osteomas of the middle ear are rare lesions. We report the case of a 20-year-old male with osteoma originating from the promontory coincident with tympanic membrane perforation. Histopathological diagnosis was performed by means of a superficial curettage during surgery, to avoid a cochlear fenestration. Postoperative closure of the air-bone gap after myringoplasty confirmed the presumed asymptomatic nature of these lesions.
Tópico(s): Bone Tumor Diagnosis and Treatments
1997 - Karger Publishers | ORL
Produção Nacional
Revisado por pares
Henrique Ataíde Isaía, Cristian Mauricio Barreto Pinilla, Adriano Brandelli,
The antimicrobial peptide produced by Bacillus velesensis P34 has a broad activity against Gram-positive bacteria, showing potential as natural food preservative. In this work, nanocapsules (NCs) containing the peptide P34 were produced using the polymers poly-ε-caprolactone (PCL) or Eudragit RS-100 (EUD), and their antimicrobial activities were assessed evaluating L. monocytogenes growth in synthetic media, milk and isolated milk proteins. As results, cationic and anionic nanocapsules were obtained, ...
Tópico(s): Proteins in Food Systems
2020 - Elsevier BV | Food Research International
Produção Nacional
Revisado por pares
Cristian Mauricio Barreto Pinilla, Paolo Stincone, Adriano Brandelli,
The ability of Listeria monocytogenes grow on ready-to-eat food is a major concern in food safety. Natural antimicrobials, such as nisin, can be used to control this pathogen, but the increasing reports of nisin tolerance and resistance make necessary novel approaches to increase its effectiveness, such as encapsulation. The goal of this study was to investigate how L. monocytogenes ATCC7644 regulates and shapes its proteome in response to sublethal doses of nisin and nisin-loaded phosphatidylcholine ...
Tópico(s): Identification and Quantification in Food
2021 - Elsevier BV | International Journal of Food Microbiology