Kim Vieira Kayat, Paulo E.C. Dantas, Sérgio Felberg, Maria Antonieta Longo Galvão, Mauro Saieg,
Surface tumors of the eye comprise an ample spectrum of diseases with various clinical manifestations. Diagnosis has been traditionally achieved through core biopsies, but cytology is an innovative, fast, and minimally invasive method. The objective of this study was to investigate the use of exfoliative cytology as an alternative method for the detection of ocular surface squamous neoplasm (OSSN).Exfoliative cytology of the lesions was performed by collecting smears using plastic brushes followed ...
Tópico(s): Cancer and Skin Lesions
2016 - Lippincott Williams & Wilkins | Cornea

Petrus Galvão, Mauro de Freitas Rebelo, João Paulo Machado Torres, Jean Remy Davée Guimarães, Olaf Malm,
The knowledge on the contaminants agents' bioaccumulation dynamics in bivalve tissues is important because shell fish consumption may represent a toxic risk to humans. By looking at the selective pressure to which the bivalve mollusks were submitted along their evolutionary process, a better understanding on bivalves as a biologic model for environmental contamination assessments can be achieved. The capacity to control toxic elements by bivalves is especially important to environment toxicology. ...
Tópico(s): Heavy metals in environment
2010 - | Brazilian Journal of Aquatic Science and Technology
Clarissa Rosa, Bruno R. Ribeiro, Vanesa Bejarano Alegre, Fernando Henrique Puertas, Adriana Bocchiglieri, Adriana Loeser dos Santos Barbosa, Adriano G. Chiarello, Adriano Pereira Paglia, Adriele Aparecida Pereira, Adryelle Francisca de Souza Moreira, Agnis Cristiane de Souza, A. O. Pellegrin, Ailín Gatica, Akyllan Zoppi Medeiro, Alan Deivid Pereira, Alan Gerhardt Braz, Alberto Yanosky, Alejandro E. J. Valenzuela, Alessandra Bertassoni, Alessandra dos Santos Venturini do Prado, Alessandra Ferreira Dales Nava, Alessandro Rocha, Alex Augusto Abreu Bovo, Alex Bager, Alexandra Cravino, Alexandra S. Pires, Alexandre Camargo Martensen, Alexandre Filippini, Alexandre Reis Percequillo, Alexandre Vogliotti, Alexsander Zamorano Antunes, Aline Cristina Leite de Oliveira, Allan Jefferson da Silva de Oliveira, Allison L. Devlin, Almir de Paula, Aluane Silva Ferreira, Alvaro García‐Olaechea, Amanda L. Subalusky, Amadeo Sánchez, Ana Carla Medeiros Morato de Aquino, Ana Carolina Srbek‐Araujo, Amane Paldês Gonçales, Ana Caroline L. Araújo, A. Cecilia Gozzi, Ana Cecilia Ochoa, Ana Cristina Mendes de Oliveira, Ana Cristyna Reis Lacerda, Ana Karina de Francisco, Ana Maria de Oliveira Paschoal, Ana Paula Nascimento Gomes, Ana Paula Potrich, Ana Priscila Medeiros Olímpio, Ana Pozuelos Rojas, Ana Yoko Ykeuti Meiga, Anah Tereza de Almeida Jácomo, Analice Maria Calaça, Anderson Feijó, Anderson Pagoto, André Sebastián Borja-Chiriboga, André Chein Alonso, André Felipe Barreto‐Lima, André Monnerat Lanna, André Luís Luza, André Restel Camilo, André Tavares, André Valle Nunes, Andreas Kindel, Andrés de Miguel, Andressa Gatti, Andrezza Bellotto Nobre, Anielise da Conceição Campêlo, Anna Carolina Figueiredo de Albuquerque, J. Antonio de la Torre, Antonio M. Mangione, Antônio Rossano Mendes Pontes, Arthur Soares Fernandes, Artur Luiz de Almeida Felício, Átilla Colombo Ferreguetti, Arlei Marcili, Augusto João Piratelli, Ariel Guilherme Santos do Nascimento, Áureo Banhos, Beatris Felipe Rosa, Beatriz Azevedo Cezila, Benoı̂t de Thoisy, Bianca Ingberman, Bianca Köhler, Bianca Cruz Morais, Bibiana Gómez‐Valencia, Bruna Bertagni de Camargo, Bruna M. Bezerra, Bruna Tamasauskas, Bruno Augusto Torres Parahyba Campos, Bruno Busnello Kubiak, Bruno H. Saranholi, Bruno Kazuo Nakagawa, Bruno Leles, Burton K. Lim, Calebe Pereira Mendes, Camila Alvez Islas, Camila Aoki, Camila Cantagallo Devids, Camila Pugliesi De Figueiredo, Camila Matias Goes de Abreu, Camila Raquel Silva Oliveira, Camila Righetto Cassano, Camile Lugarini, Carin Caputo, Carla C. Gestich, Carla Denise Tedesco, Carla Fabiane de Vera y Conde, Carla Grasiele Zanin Hegel, Carlos Benhur Kasper, Carlos De Angelo, Carlos Eduardo Viveiros Grelle, Carlos Eduardo Fragoso, Carlos Eduardo Lustosa Esbérard, Carlos Frederico Duarte Rocha, Carlos Eduardo Verona, Carlos Henrique Salvador, Carlos Leonardo Vieira, Carlos Roberto Abrahão, Carlos Rodrigo Brocardo, Carolline Zatta Fieker, Caryne Braga, Catalina Sánchez‐Lalinde, Cecília Bueno, Cássia Yumi Ikuta, Cecília Licarião Luna, César Cestári, Christine Del Vechio Koike, Christoph Knogge, Christopher B. Anderson, Cindy M. Hurtado, Cintia Ferreira Antunes de Oliveira, Cintia Gisele Tellaeche, Clarice Silva Cesário, Claudia Guimarães Costa, Claudia Zukeran Kanda, Sebastián Andrés Costa, Cristiana Simão Seixas, Cristiano Trapé Trinca, Cristina Fabiola López‐Fuerte, Cristina Jaques da Cunha, Cynthia Doutel Ribas, Cyntia Cavalcante Santos, Daiane Buscariol, Daiane Carreira, Daiane Chaves do Nascimento, Danianderson Rodrigues Carvalho, Daniel da Silva Ferraz, Daniel Galiano, Daniel Henrique Homem, Daniel Jesús‐Espinosa, Daniela Aparecida Savariz Bôlla, Daniele Janina Moreno, Danielle de Oliveira Moreira, Danielle Leal Ramos, Danilo Angelucci de Amorim, Darci Moraes Barros‐Battesti, David Echeverri Lopez, Davi Castro Tavares, David M. Post, Dayvid Rodrigues Couto, Dennis Nogarolli Patrocínio, Diana Letícia Kruger Pacheco Carvalho, Diego Afonso Silva, Diego Córdoba, Diego Queirolo, Diego� Varela, Dilmar Alberto Gonçalves de Oliveira, Diogo Cavenague Casanova, Douglas de Matos Dias, Douglas Machado da Silva, Eder Barbier, Edgar Federico Rivadeneira, Eduardo Roberto Alexandrino, Eduardo Carrano, Eduardo Marques Santos, Eduardo Martins Venticinque, Edwin L. Hernández-Pérez, Egberto da Fonseca Casazza, Elizabeth P. Anderson, Elmary da Costa Fraga, Elson Fernandes de Lima, Elvira D’Bastiani, Emerson Monteiro Vieira, Emiliano Guijosa‐Guadarrama, Enrique M. González, Erica Vanessa Maggiorini, Erick Francisco Silva de Aguiar, Erik Daniel Martínez‐Nambo, Érika Paula Castro, Erika de la Peña‐Cuéllar, Ezequiel Pedó, Fabiana Cristina Silveira Alves de Melo, Fabiana Lopes Rocha, Fabiana Luques Fonseca, Fabiane Girardi, Fabiano Rodrigues de Melo, Fábio de Oliveira Roque, Fabíola Keesen, Felipe Bortolotto Peters, Felipe Moreli Fantacini, Felipe Pedrosa, Felipe Pessoa da Silva, Felipe Vélez‐García, Fernanda Delborgo Abra, Fernanda Cavalcanti de Azevedo, Fernanda Guedes da Silva, Fernanda Maria Neri, Fernanda Zimmermann Teixeira, Fernando Antonio dos Santos Fernandez, Fernando Carvalho, Fernandode Camargo Passos, Fernando de Castro Jacinavicius, Fernando Ferreira, Fernando Ferreira de Pinho, Fernando Gonçalves, Fernando Ibanez Martins, Fernando Lima, Fernando M. Contreras‐Moreno, Fernando Silvério Ribeiro, Fernando Rodrigo Tortato, F.M.PATEL F.M.PATEL, Flavia Caruso, Flávia Pereira Tirelli, Flávio Henrique Guimarães Rodrigues, Flávio Kulaif Ubaid, Francesca Belem Lopes Palmeira, Francisco Grotta‐Neto, Francisco Homem Gabriel, Franco L. Souza, Francys E. da Veiga da Costa, Gabriel Lima Aguiar, Frederico Gemesio Lemos, Gabriel Shimokawa Magezi, Gabriel Ferreira Vianna Di Panigai, Gabriel Selbach Hofmann, Gabriela Heliodoro, Gabriela Rosa Graviola, Gabrielle Beca, Gabrielle Ribeiro de Andrade, Germán Jiménez, Gabriela Teixeira Duarte, Geruza Leal Melo, Geverson Luiz Dierings, Gilberto Sabino‐Santos, Geovana Linhares de Oliveira, Gindomar Gomes Santana, Giordano Ciocheti, Gisele Lamberti Zanirato, Giselle Bastos Alves, Graziele Oliveira Batista, Greici Maia Behling, Guilherme Braga Ferreira, Guilherme Casoni da Rocha, Gisele Lessa, Guilherme Mourão, Gustavo A. Marás, Gustavo Alves da Costa Toledo, Gustavo Gonsioroski, Gustavo Rodrigues Canale, Karl‐Ludwig Schuchmann, Harley Sebastião, Helena Alves do Prado, Helena Godoy Bergallo, Helio Secco, Henrique Llacer Roig, Henrique Rajão, Henrique Santiago Alberto Carlos, Herbert O. B. Duarte, Hiago Ermenegildo, Hilda Fátima Jesus Pena, Hilton Entringer, Hipólito Ferreira Paulino Neto, Hudson de Macedo Lemos, Hugo del Castillo, Hugo Fernandes‐Ferreira, Hugo Ignacio Coitiño Banquero, Ignacio Roesler, Igor Kintopp Ribeiro, Igor Pfeifer Coelho, Ingrid M. S. Lima, Isabel Muniz Bechara, Isabel Salgueiro Lermen, Isac Mella-Méndez, Gabriela Schuck, Isadora Beraldi Esperandio, Ita de Oliveria Silva, Ítalo Mourthé, Igor Oliveira, Itiberê P. Bernardi, Jacqueline R. Miller, Jader Marinho‐Filho, Jairo José Zocche,
Biological invasion is one of the main threats to native biodiversity. For a species to become invasive, it must be voluntarily or involuntarily introduced by humans into a nonnative habitat. Mammals were among first taxa to be introduced worldwide for game, meat, and labor, yet the number of species introduced in the Neotropics remains unknown. In this data set, we make available occurrence and abundance data on mammal species that (1) transposed a geographical barrier and (2) were voluntarily or ...
Wiley

Ana Beatriz Ayroza Galvão Ribeiro Gomes, Mauro Henrique, Vinícius Andreoli Schoeps, Mariana Monteiro Saldanha Altenfelder Santos, Ada Pellegrinelli, Bárbara Pessoa de Matos, Gabriel Taricani Kubota, Haniel A. Araújo, Letícia Sant' Ana Cardoso da Silva, Fabrício de Paula Leite Battisti, Bruno Y. Kubota, Areta Cavalcanti Ferreira, Mateus Paquesse Pellegrino, Renata de Andrade Prado, Ronaldo Abrahm, Vivian Dias Baptista Gagliardi, Marcel Simis, Rubens José Gagliardi,
Cerebrovascular disease is one of the most important causes of death and disability worldwide. The patient's inability to identify the warning signs of stroke substantially delays the search for emergency services, which is related directly to a worse outcome. Thus, during the 2011 Stroke Campaign in Brazil, a survey was conducted to identify the lay population's knowledge with regard to the recognition, treatment, and prevention of stroke.This retrospective, cross-sectional, multicenter study was ...
Tópico(s): Stroke Rehabilitation and Recovery
2016 - Elsevier BV | eNeurologicalSci

Bruno Vinícius Santos Valiate, Celso Martins Queiroz‐Junior, Francesca Levi‐Schaffer, Izabela Galvão, Mauro Martins Teixeira,
Abstract Gout is an inflammatory disease triggered by deposition of monosodium urate (MSU) crystals in the joints, resulting in high neutrophil influx and pain. Here, we studied the role of the inhibitory receptor CD300a in the resolution process in a murine model of gout. We found increased CD300a expression on neutrophils emigrated to the joint. When compared to WT mice, CD300a −/− mice had persistent neutrophil influx till 24 hr after MSU injection. This was associated with increased concentration ...
Tópico(s): Gout, Hyperuricemia, Uric Acid
2021 - Wiley | Immunology

Marcus Vinícius Dantas de Campos Martins, James Skinovsky, Djalma Ernesto Coelho, Almino Ramos, Manoel Galvão Neto, José Mauro da Silva Rodrigues, Luiz de Carli, Leandro Totti Cavazolla, Josemberg Marins Campos, Fábio Thuller, Adriano Brunetti,
Background: The advent of endoscopic surgery has radically changed surgery worldwide.The concept of minimally invasive procedures has spread quickly, allowing less pain and more rapid recovery for patients. The authors have developed a device for a new surgical approach, the so-called single trocar access (SITRACC). This study report the first multicenter study of cholecystectomies performed with SITRACC. Methods: Between December 2008 and June 2009, 81 single trocar cholecystectomies were performed ...
Tópico(s): Intestinal Malrotation and Obstruction Disorders
2009 - SAGE Publishing | Surgical Innovation

Angélica T. Vieira, Izabela Galvão, Flávio A. Amaral, Mauro Martins Teixeira, Jacques R. Nicoli, Flaviano S. Martins,
Gout is an acute inflammatory disease characterised by the presence of uric acid crystals in the joint. This event promotes neutrophil infiltration and activation that leads to tissue damage. We investigated here whether the oral administration of the probiotic strain Bifidobacterium longum 5 1A (BL) could ameliorate monosodium urate crystal (MSU)-induced inflammation in a murine model of gout. Mice received oral administration of BL or saline daily for 7 days and then were injected with MSU in the ...
Tópico(s): Streptococcal Infections and Treatments
2015 - | Beneficial Microbes

Luiz Augusto Silva de Sousa, Jessivaldo Rodrigues Galvão, Mauro Junior Borges Pacheco, Gabriel da Silva Vasconcelos, Andréia Costa de Sousa,
The aim of this study was to evaluate the influence of vegetation management on soil chemical attributes during the implementation of an agroforestry system in Pará, Brazil. Three treatments were evaluated - T1 Control (secondary vegetation - SF), T2 - Fire management system (FMS) and T3 - Management system without vegetation burning (MSWB). Soil samples were collected at 30 cm deep to analyze chemical attributes. The data were analyzed using Analysis of Variance - ANOVA, and the t-test. Treatment T2 caused ...
Tópico(s): Environmental and biological studies
2020 - Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências | Research Society and Development

Viviani Mendes de Almeida, Daiane F. Engel, Mayra Fernanda Ricci, Clênio Silva Cruz, Ícaro Santos Lopes, Daniele Almeida Alves, Mirna d’ Auriol, João Magalhães, Elayne Cristina Machado, Victor Rocha, Toniana G. Carvalho, Larisse S. B. Lacerda, Jordane Clarisse Pimenta, Mariana Aganetti, Giuliana S. Zuccoli, Bradley J. Smith, Victor Corasolla Carregari, Erika da Silva Rosa, Izabela Galvão, Geovanni Dantas Cassali, Cristiana C. Garcia, Mauro Martins Teixeira, Leiliane Coelho André, Fabíola M. Ribeiro, Flaviano S. Martins, Rafael Simone Saia, Vivian Vasconcelos Costa, Daniel Martins‐de‐Souza, Philip M. Hansbro, João T. Marques, Eric Roberto Guimarães Rocha Aguiar, Angélica T. Vieira,
Long-term sequelae of coronavirus disease (COVID)-19 are frequent and of major concern. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection affects the host gut microbiota, which is linked to disease severity in patients with COVID-19. Here, we report that the gut microbiota of post-COVID subjects had a remarkable predominance of Enterobacteriaceae strains with an antibiotic-resistant phenotype compared to healthy controls. Additionally, short-chain fatty acid (SCFA) levels were ...
Tópico(s): Cannabis and Cannabinoid Research
2023 - Landes Bioscience | Gut Microbes

Graziele L. Negreiros-Lima, Kátia M. Lima, Isabella Zaidan, Bruna Lorrayne O. Jardim, Juliana P. Vago, Izabela Galvão, Lívia Cristina Ribeiro Teixeira, Vanessa Pinho, Mauro Martins Teixeira, Michelle A. Sugimoto, Lirlândia P. Sousa,
Macrophages are central to inflammation resolution, an active process aimed at restoring tissue homeostasis following an inflammatory response. Here, the effects of db-cAMP on macrophage phenotype and function were investigated. Injection of db-cAMP into the pleural cavity of mice induced monocytes recruitment in a manner dependent on PKA and CCR2/CCL2 pathways. Furthermore, db-cAMP promoted reprogramming of bone-marrow-derived macrophages to a M2 phenotype as seen by increased Arg-1/CD206/Ym-1 ...
Tópico(s): Immune responses and vaccinations
2020 - Multidisciplinary Digital Publishing Institute | Cells

Isabella Zaidan, Luciana P. Tavares, Michelle A. Sugimoto, Kátia M. Lima, Graziele L. Negreiros-Lima, Lívia Cristina Ribeiro Teixeira, Thaís C. Miranda, Bruno Vinícius Santos Valiate, Allysson Cramer, Juliana P. Vago, Gabriel Henrique Campolina-Silva, Jéssica A.M. Souza, Laís C. Grossi, Vanessa Pinho, Maria José Campagnole‐Santos, Robson A.S. Santos, Mauro Martins Teixeira, Izabela Galvão, Lirlândia P. Sousa,
Nonphlogistic migration of macrophages contributes to the clearance of pathogens and apoptotic cells, a critical step for the resolution of inflammation and return to homeostasis. Angiotensin-(1-7) [Ang-(1-7)] is a heptapeptide of the renin-angiotensin system that acts through Mas receptor (MasR). Ang-(1-7) has recently emerged as a novel proresolving mediator, yet Ang-(1-7) resolution mechanisms are not fully determined. Herein, Ang-(1-7) stimulated migration of human and murine monocytes/macrophages ...
Tópico(s): Apelin-related biomedical research
2021 - American Society for Clinical Investigation | JCI Insight

Luiz Fernando Favarato, Jacimar Luís de Souza, João Carlos Cardoso Galvão, Caetano Marciano de Souza, Rogério Carvalho Guarçoni, José Mauro de Souza Balbino,
RESUMO O cultivo de diferentes espécies de plantas de cobertura possibilita a melhoria e a conservação do solo e da matéria orgânica, além de promover consideráveis aumentos de rendimento nas culturas subsequentes, com significativos ganhos econômicos. Objetivou-se avaliar o crescimento e produtividade de milho-verde sobre diferentes coberturas de solo no sistema plantio direto (SPD) orgânico. O trabalho foi disposto em delineamento de blocos casualizados, com 6 repetições e 5 sistemas de produção, ...
Tópico(s): Growth and nutrition in plants
2016 - INSTITUTO AGRONÔMICO DE CAMPINAS | Bragantia

Flávia Rago, Eliza Mathias Melo, Lucas Kraemer, Izabela Galvão, Geovanni Dantas Cassali, Robson A.S. Santos, Remo Castro Russo, Mauro Martins Teixeira,
Abstract Idiopathic pulmonary fibrosis is characterized by aberrant fibroblast activation and excessive collagen deposition that may eventually lead to organ dysfunction. Lung fibrosis is frequently observed in cancer patients undergoing bleomycin (BLM) treatment. Therefore, BLM instillation in mice is the most frequent model used to investigate pulmonary fibrosis. Angiotensin 1–7 [Ang-(1-7)] is a heptapeptide with anti-inflammatory and proresolving activity. Here, we studied the effects of preventive ...
Tópico(s): Inhalation and Respiratory Drug Delivery
2019 - Oxford University Press | Journal of Leukocyte Biology

José Domingos Fabris, Mauro Resende, E. Galvao Da Silva, J. M. D. Coey,
SUMMARY Two Oxisols from the B2 horizon at similar locations 2 km apart on the Brazilian coastal plain with a udic, isohyperthermic regime were practically identical in chemical composition but differed markedly in colour; one was a dark reddish brown, the other a pale ochre. Mossbauer spectra at 295 K, 80 K and 4.2 K indicated a clear difference in iron oxide mineralogy. Iron was present as aluminous hematite and goethite, with Al substitutions of approximately 20% in the two phases. However, the ...
Tópico(s): Geochemistry and Elemental Analysis
1985 - Wiley | Journal of Soil Science

Kátia M. Lima, Juliana P. Vago, Thaís Rolla de Caux, Graziele L. Negreiros-Lima, Michelle A. Sugimoto, Luciana P. Tavares, Raquel Gregório Arribada, Aline A. F. Carmo, Izabela Galvão, Bruno Rocha Cordeiro Costa, Frederico Marianetti Soriani, Vanessa Pinho, Egle Solito, Mauro Perretti, Mauro Martins Teixeira, Lirlândia P. Sousa,
Tópico(s): Protease and Inhibitor Mechanisms
2017 - Elsevier BV | Journal of Biological Chemistry

Luciana P. Tavares, Cristiana C. Garcia, Juliana P. Vago, Celso Martins Queiroz‐Junior, Izabela Galvão, Bruna Araújo David, Milene Alvarenga Rachid, Patrı́cia Silva, Remo Castro Russo, Mauro Martins Teixeira, Lirlândia P. Sousa,
Pneumococcal pneumonia is a leading cause of mortality worldwide. The inflammatory response to bacteria is necessary to control infection, but it may also contribute to tissue damage. Phosphodiesterase-4 inhibitors, such as rolipram (ROL), effectively reduce inflammation. Here, we examined the impact of ROL in a pneumococcal pneumonia murine model. Mice were infected intranasally with 10(5)-10(6) CFU of Streptococcus pneumoniae, treated with ROL in a prophylactic or therapeutic schedule in combination, ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2015 - American Thoracic Society | American Journal of Respiratory Cell and Molecular Biology

Flávio A. Amaral, Leandro F.S. Bastos, Thiago Henrique Oliveira, Ana Carolina Fialho Dias, Vívian Louise Soares de Oliveira, Lívia D. Tavares, Vivian Vasconcelos Costa, Izabela Galvão, Frederico Marianetti Soriani, David E. Szymkowski, Bernhard Ryffel, Danielle G. Souza, Mauro Martins Teixeira,
Gout manifests as recurrent episodes of acute joint inflammation and pain due to the deposition of monosodium urate (MSU) crystals within the affected tissue in a process dependent on NLRP3 inflammasome activation. The synthesis, activation, and release of IL-1β are crucial for MSU-induced inflammation. The current study evaluated the mechanism by which TNF-α contributed to MSU-induced inflammation. Male C57BL/6J or transgenic mice were used in this study and inflammation was induced by the injection ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2015 - Wiley | European Journal of Immunology

Felipe Oliveira Ribeiro, Antônio Rodrigues Fernandes, Jessivaldo Rodrigues Galvão, Gilson Sérgio Bastos de Matos, Marcelo Morita Lindolfo, Cássio Rafael Costa dos Santos, Mauro Junior Borges Pacheco,
Information about Açaí palm (Euterpe oleracea Mart.) nutrition, that gives support for yield increase is sparse. The aim of this study was to assess the nutritional status of fertigated Açaí palm by the Index called Diagnosis and Recommendation Integrated System (DRIS), as well as the spatial variability of this Index and its productivity. We achieved a sampling of 80 geo-referenced points in an Açaí palm commercial crop area. Then we assessed the yield and contents of N, P, K, Ca, Mg, S, B, Cu, Fe, ...
Tópico(s): Soil Geostatistics and Mapping
2020 - Taylor & Francis | Journal of Plant Nutrition

Izabela Galvão, Celso Martins Queiroz‐Junior, Vívian Louise Soares de Oliveira, Vanessa Pinho, Emilio Hirsch, Mauro Martins Teixeira,
Phosphoinositide-3 kinases (PI3Ks) are central signalling enzymes that are involved in many aspects of immune cell function. PI3Kγ and PI3Kδ are the major isoforms expressed in leukocytes. The role of PI3K isoforms in the resolution of inflammation is still poorly understood. Here, we investigated the contribution of PI3Kγ and PI3Kδ to the resolution of inflammation in a model of gout in mice. Methods and Results: Experiments were performed in wild-type male C57/Bl6 mice. Selective inhibitors of ...
Tópico(s): Eosinophilic Disorders and Syndromes
2019 - Frontiers Media | Frontiers in Pharmacology

Z. Brener, J. Romeu Cançado, Lúcia Maria da Cunha Galvão, Zélia Maria Profeta da Luz, Leny de Sousa Filardi, Maria Elizabeth S Pereira, Luiz Mauro T. Santos, Catarina B. Cançado,
Ketoconazole, an azole antifungic drug which is already in the market has also been demonstrated to be active against Trypanosoma cruzi experimental infections. In this paper we confirmed the drug effect and investigated its range of activity against different T. cruzi strains naturally resistant or susceptible to both standard drugs Nifurtimox and Benznidazole used clinically in Chagas disease. Moreover, we have shown that the association of Ketoconazole plus Lovastatin (an inhibitor of sterol synthesis), ...
Tópico(s): Synthesis and Biological Evaluation
1993 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz

Arthur Gustavo Fernandes, Andrew Bastawrous, Nívea Nunes Ferraz, Benjamin D. Hennig, Vagner Loduca Lima, Rodrigo Galvão Viana, Mauro Campos, João M. Furtado,
To evaluate athletes' frequency of attendance at the eye clinic during the Olympic and Paralympic Games Rio 2016 and to correlate it to WHO core indicators on progress in ophthalmology care in a country.
Tópico(s): Traumatic Ocular and Foreign Body Injuries
2020 - BMJ | British Journal of Sports Medicine

Helio Rzetelna, Carlos Frederico Porto Alegre Rosa, Mario Kirzner, Lucas Pereira Jorge de Medeiros, Camila Melo, Márcia Gonçalves Ribeiro, Lisa Oliveira, José Galvão Alves, Mauro Geller,
Objectives: The purpose of this study was to evaluate and compare the use of propinox hydrochloride and scopolamine hydrochloride in patients presenting abdominal colic (abdominal pain), in terms of treatment efficacy and tolerability. Material & Methods: This was an analytical, retrospective, comparative study based on hospital records of outpatients treated at Serviço de Clínica Médica do Hospital das Clínicas Costantino Otaviano (HCTCO) and at Santa Casa de Misericórdia do Rio de Janeiro, from ...
Tópico(s): Intestinal and Peritoneal Adhesions
2016 - Scientific Research Publishing | International Journal of Clinical Medicine

Mauro Shosuka Asato, Roberto Carlos Cruz Carbonell, Alessandra Galvão Martins, Cléria Mendonça de Moraes, Carlos Chávez-Olórtegui, Maria Apolônia da Costa Gadelha, Pedro Pereira de Oliveira Pardal,
The aim of this study was to evaluate the clinical-epidemiological factors associated with victims of rattlesnake envenoming in the state of Roraima, Brazil. In this location, rattlesnake accidents are caused by the subspecies Crotalus durissus ruruima. This is a prospective observational study carried out at the General Hospital of Roraima from april 2017 until july 2018. A total of 37 alleged rattlesnake victims had their medical records evaluated. However only one of them proved to be by C. d. ...
Tópico(s): Healthcare and Venom Research
2020 - Elsevier BV | Toxicon X

Márcio Nucci, Kieren A. Marr, Maria J. G. T. Vehreschild, Cármino Antônio De Souza, E. Velasco, Paola Cappellano, Fabianne Carlesse, Flávio Queiroz‐Telles, Donald C. Sheppard, A. J. Kindo, Simone Cesaro, Nelson Hamerschlak, Cristiana Solza, Werner Heinz, M. Schaller, Ângelo Atalla, Sevtap Arıkan-Akdağlı, Hartmut Bertz, Cláudio Galvão de Castro, Raoul Herbrecht, Martin Hoenigl, Georg Härter, Emil Hermansen, Andreas Josting, Livio Pagano, Mauro José Costa Salles, Sherif B. Mossad, Dilara Öğünç, Alessandro C. Pasqualotto, Vitória Emily Santana De Araújo, Peter F. Troke, Olivier Lortholary, O.A. Comely, E. Anaissie,
Invasive fusariosis (IF) has been associated with a poor prognosis. Although recent series have reported improved outcomes, the definition of optimal treatments remains controversial. The objective of this study was to evaluate changes in the outcome of IF. We retrospectively analysed 233 cases of IF from 11 countries, comparing demographics, clinical findings, treatment and outcome in two periods: 1985–2000 (period 1) and 2001–2011 (period 2). Most patients (92%) had haematological disease. Primary ...
Tópico(s): Plant Pathogens and Fungal Diseases
2013 - Elsevier BV | Clinical Microbiology and Infection

Andréa Carvalho De Marco, Camila Galvão Cardoso, Fernando Vinicius Cesar De Marco, Antônio Braulino de Melo Filho, Mauro Pedrine Santamaría, Maria Aparecida Neves Jardini,
INTRODUCTION: Literature has reported inadequate oral hygiene conditions in Intensive Care Unit (ICU) patients and the occurrence of Ventilator-associated pneumonia in about 9%-27% of all intubated patients. OBJECTIVE: The aim of this study was to evaluate ICU patient's oral conditions and correlate this with the presence of ventilator-associated pneumonia. MATERIAL AND METHOD: Twenty-three patients were categorized in the following way: with periodontal disease and ventilator-associated pneumonia, ...
Tópico(s): Oral microbiology and periodontitis research
2013 - UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO | Revista de Odontologia da UNESP

Brenda Rocha Guimarães, Ana Regina da Rocha Araújo, Jessivaldo Rodrigues Galvão, Mauro Junior Borges Pacheco, Sérgio Brazão e Silva, Luiz Felipe Conceição Tavares de Assis, Jorge Cardoso de Azevedo, Kleslie de Carvalho Moraes,
A quantidade e a proporcionalidade dos nutrientes absorvidos pelas plantas são funções de características intrínsecas do vegetal, como, também, dos fatores externos que condicionam o processo. Numa espécie, a capacidade em retirar os nutrientes do solo e as quantidades requeridas variam não só com a cultivar, mas também com o grau de competição existente. Variações nos fatores ambientais como temperatura e umidade do solo podem afetar o conteúdo de nutrientes minerais nas folhas consideravelmente. ...
Tópico(s): Pineapple and bromelain studies
2020 - Escola Superior de Sustentabilidade | Revista Ibero-Americana de Ciências Ambientais

Melissa de Carvalho Santuchi, Miriane Fernandes Dutra, Juliana P. Vago, Kátia M. Lima, Izabela Galvão, Fernando Souza-Neto, Mário Morais Silva, Aline C. Oliveira, Flávia Carvalho Bittencourt de Oliveira, Ricardo Gonçalves, Mauro Martins Teixeira, Lirlândia P. Sousa, Robson A.S. Santos, Rafaela da Silva,
The renin-angiotensin system (RAS) peptides play an important role in inflammation. Resolution of inflammation contributes to restore tissue homeostasis, and it is characterized by neutrophil apoptosis and their subsequent removal by macrophages, which are remarkable plastic cells involved in the pathophysiology of diverse inflammatory diseases. However, the effects of RAS peptides on different macrophage phenotypes are still emerging. Here, we evaluated the effects of angiotensin-(1-7) (Ang-(1-7)) ...
Tópico(s): Renin-Angiotensin System Studies
2019 - Hindawi Publishing Corporation | Mediators of Inflammation

Rhonan Ferreira Silva, Camilla Galvão Vaz, Mariana Leão Domiciano, Ademir Franco, Carla Nunes, Mauro Machado do Prado,
The frontal sinuses play a highly relevant role in comparative human identification processes. Since forensic radiology is a branch in the forensic sciences, adequate radiological analysis of the frontal sinuses is essential for comparative human identifications. The current study investigates radiographic morphological changes in the frontal sinuses according to vertical angle distortions in posteroanterior (PA) radiographs. A standard PA radiograph of the skull of an adult was obtained. Eight addition ...
Tópico(s): Facial Trauma and Fracture Management
2014 - UNIVERSIDADE ESTADUAL DE MARINGÁ | Acta Scientiarum Health Sciences

Juliana Lauar Gonçalves, Norinne Lacerda‐Queiroz, Josiane F.L. Sabino, Pedro Elias Marques, Izabela Galvão, Conrado de Oliveira Gamba, Geovanni Dantas Cassali, Luana Martins de Carvalho, Daniel Almeida da Silva e Silva, Adaliene Versiani, Mauro Martins Teixeira, Ana Maria Caetano Faria, Angélica T. Vieira, Ana Lúcia Brunialti Godard,
Alcoholism is a multifactorial and complex disorder responsible for 5.9% of deaths worldwide. Excessive consumption of ethanol (Et-OH) induces alcoholic liver disease (ALD), a condition comprising a spectrum of clinical signs and morphological changes, ranging from fatty liver (steatosis) to more severe forms of chronic liver injury. Secondary cofactors, such as nutritional and hepatotoxic comorbid conditions, can also contribute to liver disease development. Here we investigated the effects in the ...
Tópico(s): Diet, Metabolism, and Disease
2016 - Elsevier BV | The Journal of Nutritional Biochemistry

Ismael de Jesus Matos Viégas, Jessivaldo Rodrigues Galvão, Alasse Oliveira da Silva, Heráclito Eugênio Oliveira da Conceição, Mauro Junior Borges Pacheco, Thiago Costa Viana, Eric Vitor de Oliveira Ferreira, Ricardo Shigueru Okumura, Diocléa Almeida Seabra Silva,
In Brazil, the status of chlorine (Cl) nutrition in plants is still poorly studied. The micronutrient Cl plays an important role in cultures such as coconut and oil palm trees. This study aimed to evaluate the status of chlorine nutrition in oil palm trees as a function of planting age, which ranged from two to eight years of cultivation. The experiment was conducted in Tailândia, state of Pará, Brazil. The soil of the area is characterized as Yellow Latosol of medium texture. A total of four oil ...
Tópico(s): Oil Palm Production and Sustainability
2020 - | Journal of Agricultural Studies