Jillian R. Tate, Robert L. Jesse, L. Kristin Newby, Mauro Panteghini, Robert H. Christenson, Robert H. Christenson, Jillian R. Tate, Christopher P. Cannon, Gary S. Francis, Robert L. Jesse, David A. Morrow, LK Newby, Jan Ravkilde, Alan B. Storrow, W.H. Wilson Tang, Mauro Panteghini, Jillian R. Tate, Robert H. Christenson, A S Jaffe, Johannes Mair, Jordi Ordóñez‐Llanos, Francesca Pagani, Mauro Panteghini, Jillian R. Tate, Mauro Panteghini,
### a. Background In 1999, the National Academy of Clinical Biochemistry (NACB)1 published the first standards of laboratory practice addressing analytical and clinical recommendations for use of cardiac markers in coronary artery diseases (1). The objectives were to recommend the appropriate implementation and utilization of cardiac biomarkers, specifically for cardiac troponin (cTn), which had just gained US Food and Drug Administration (FDA) clearance as a cardiac biomarker to aid in the diagnosis of ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2007 - American Association for Clinical Chemistry | Clinical Chemistry
Gita A. Pathak, Juha Karjalainen, Christine Stevens, Benjamin M. Neale, Mark J. Daly, Andrea Ganna, Shea J. Andrews, Masahiro Kanai, Mattia Cordioli, Renato Polimanti, Nadia V. Harerimana, Matti Pirinen, Rachel G. Liao, Karolina Chwiałkowska, Amy Trankiem, Mary K. Balaconis, Huy Nguyen, Matthew Solomonson, Kumar Veerapen, Brooke N. Wolford, Genevieve Roberts, Daniel J. Park, Catherine A. Ball, Marie V. Coignet, Shannon McCurdy, Spencer C. Knight, Raghavendran Partha, Brooke Rhead, Miao Zhang, Nathan Berkowitz, Michael Gaddis, Keith Noto, Luong Ruiz, Miloš Pavlović, Eurie L. Hong, Kristin A. Rand, Ahna R. Girshick, Harendra Guturu, Asher Haug Baltzell, Mari Niemi, Souad Rahmouni, Julien Guntz, Y Beguin, Mattia Cordioli, Sara Pigazzini, Lindokuhle Nkambule, Michel Georges, Michel Moutschen, Benoît Misset, Gilles Darcis, Julien Guiot, Samira Azarzar, Stéphanie Gofflot, Sabine Claassen, Olivier Malaise, Pascale Huynen, Christelle Meuris, Marie Thys, Jessica Jacques, Philippe Léonard, Frédéric Frippiat, Jean‐Baptiste Giot, Anne-Sophie Sauvage, Christian Von Frenckell, Yasmine Belhaj, Bernard Lambermont, Tomoko Nakanishi, David Morrison, Vincent Mooser, J. Brent Richards, Guillaume Butler‐Laporte, Vincenzo Forgetta, Rui Li, Biswarup Ghosh, Lætitia Laurent, Alexandre Bélisle, Danielle Henry, Tala Abdullah, Olumide Adeleye, Noor Mamlouk, Nofar Kimchi, Zaman Afrasiabi, Nardin Rezk, Branka Vulesevic, Meriem Bouab, Charlotte Guzman, Louis Petitjean, Chris Tselios, Xiaoqing Xue, Jonathan Afilalo, Marc Afilalo, Maureen Oliveira, Bluma Brenner, Nathalie Brassard, Madéleine Durand, Erwin Schurr, Pierre Lepage, Jiannis Ragoussis, Daniel Auld, Michaël Chassé, Daniel E. Kaufmann, G. Mark Lathrop, Darin Adra, Caroline Hayward, Joseph Glessner, Douglas M. Shaw, Archie Campbell, Marcela Morris, Hákon Hákonarson, David J. Porteous, Jennifer E. Below, Anne Richmond, Xiao Chang, Hannah Polikowski, Petty E. Lauren, Hung‐Hsin Chen, Wanying Zhu, Chloe Fawns‐Ritchie, Kari E. North, Joseph B. McCormick, Xiao Chang, Joseph R. Glessner, Hákon Hákonarson, Christopher R. Gignoux, Stephen J. Wicks, Kristy Crooks, Kathleen C. Barnes, Michelle Daya, Jonathan Shortt, Nicholas Rafaels, Amr Sameer, Paul R. H. J. Timmers, James F. Wilson, Albert Tenesa, Shona M. Kerr, Kenton D’Mellow, Doaa Shahin, Yasser M. El‐Sherbiny, Kathrin Aprile von Hohenstaufen, Ali Sobh, Madonna M. Eltoukhy, Lindokuhle Nkambul, Tamer Elhadidy, Mohamed S. Abd Elghafar, Jehan J. El‐Jawhari, Attia A. S. Mohamed, Marwa H. Elnagdy, Amr Samir, Mahmoud Abdel-Aziz, Walid T. Khafaga, Walaa M. El-Lawaty, Mohamed Torky, Mohamed El‐Shanshory, Amr M. Yassen, Mohamed Hegazy, Kamal Okasha, Mohammed Eid, Hanteera S. Moahmed, Carolina Medina‐Gómez, M. Arfan Ikram, André G. Uitterlinden, Reedik Mägi, Lili Milani, Andres Metspalu, Triin Laisk, Kristi Läll, Maarja Lepamets, Tõnu Esko, Ene Reimann, Paul Naaber, Edward Laane, Jaana Pesukova, Pärt Peterson, Kai Kisand, Jekaterina Tabri, Raili Allos, Kati Hensen, Joel Starkopf, Inge Ringmets, Anu Tamm, Anne Kallaste, Helene Alavere, Kristjan Metsalu, Mairo Puusepp, Chiara Batini, Martin D. Tobin, Laura D. Venn, Paul H. Lee, Nick Shrine, Alexander T. Williams, Anna L. Guyatt, Catherine John, Richard Packer, Altaf Ali, Robert C. Free, Xueyang Wang, Louise V. Wain, Edward J. Hollox, Catherine Bee, Emma L. Adams, Aarno Palotie, Samuli Ripatti, Sanni Ruotsalainen, Kati Kristiansson, Sami Koskelainen, Markus Perola, Kati Donner, Katja Kivinen, Aarno Palotie, Mari Kaunisto, Carlo Rivolta, Pierre-Yves Bochud, Stéphanie Bibert, Noémie Boillat‐Blanco, Semira Gonseth, Werner C. Albrich, Mathieu Quinodoz, Dhryata Kamdar, Noémie Suh, Dionysios Neofytos, Véronique Erard, Cathy Voide, Pierre-Yves Bochud, Carlo Rivolta, Stéphanie Bibert, Mathieu Quinodoz, Dhryata Kamdar, Dionysios Neofytos, Véronique Erard, Cathy Voide, R. Friolet, Péter Vollenweider, Jl Pagani, Mauro Oddo, Friederike Meyer zu Bentrup, A. Conen, Olivier Clerc, Oscar Marchetti, A. Guillet, C. Guyat-Jacques, S. Foucras, M. Rime, J. Chassot, M. Jaquet, R. Merlet Viollet, Y. Lannepoudenx, L. Portopena, Pierre-Yves Bochud, Péter Vollenweider, Jl Pagani, F. Desgranges, Paraskevas Filippidis, Benoît Guéry, David Haefliger, Eleftheria Kampouri, Oriol Manuel, Aline Munting, Matthaios Papadimitriou‐Olivgeris, Jean Regina, L. Rochat-Stettler, V. Suttels, Eliana Tadini, J Tschopp, Mathias Van Singer, Benjamin Viala, Noémie Boillat‐Blanco, T. Brahier, Olivier Hügli, J. Y. Meuwly, O. Pantet, Semira Gonseth, Pierre‐Yves Bochud, Valérie D’Acremont, S. Estoppey Younes, Werner C. Albrich, Noémie Suh, A. Cerny, L. O’Mahony, C. von Mering, Pierre-Yves Bochud, Mirjam Frischknecht, G-R. Kleger, M. Filipovic, C. R. Kahlert, Hannah Wozniak, Tommaso Rochat Negro, J. Pugin, Konstantinos Bouras, C. Knapp, Thomas Egger, A. Perret, P. Montillier, C. di Bartolomeo, Beatrice Barda, Rafael de Cid, Anna Carreras,
Nature Portfolio
Filippo Maria D’Arcangelo, Ilai Levin, Anna Pagani, Mauro Pisu, Åsa Johansson,
Global progress towards tackling climate change is lagging. This paper puts forward a framework to design comprehensive decarbonisation strategies while promoting growth and social inclusion. It first highlights the need of evaluating a country's national climate targets and current policy mix, in conjunction with facilitating monitoring tools to assess current and future progress, as a key step to design effective decarbonisation strategies. It then provides a detailed comparison of several policy ...
Tópico(s): Environmental Impact and Sustainability
2022 - | OECD economic policy papers
Produção Nacional
Revisado por pares
Massimo Sartelli, Francesco M. Labricciosa, Federico Coccolini, Raúl Coimbra, Fikri M. Abu‐Zidan, Luca Ansaloni, Majdi N. Al‐Hasan, Shamshul Ansari, Philip S. Barie, Miguel Caínzos, Marco Ceresoli, Massimo Chiarugi, Jeffrey A. Claridge, Enrico Cicuttin, E. Patchen Dellinger, Donald E. Fry, Xavier Guirao, Timothy Craig Hardcastle, Andreas Hecker, Ari Leppäniemi, Andrey Litvin, Sanjay Marwah, Emilio Maseda, John E. Mazuski, Ziad A. Memish, Andrew W. Kirkpatrick, Léonardo Pagani, Mauro Podda, Kemal Raşa, Boris Sakakushev, Robert G. Sawyer, Fabio Tumietto, Yonghong Xiao, Wedad Faraj Aboubreeg, Harissou Adamou, Lali Akhmeteli, Emrah Akın, Maria Grazia Alberio, Felipe Alconchel, Ibrahim Amadou Magagi, Ana Belén Araúz, Giulio Argenio, Boyko Atanasov, Semra Demirli Atıcı, Selmy Awad, Efstratia Baili, Lovenish Bains, Miklosh Bala, Oussama Baraket, Suman Baral, В. А. Бельский, Moussa Benboubker, Offir Ben‐Ishay, Pierpaolo Bordoni, Abdalia Boumédiène, Giuseppe Brisinda, Laura Cavazzuti, Sujith J Chandy, Maria Michela Chiarello, Nicola Cillara, Guglielmo Clarizia, Maria-Elena Cocuz, Iuliu Gabriel Cocuz, Luigi Conti, Raffaella Coppola, Yunfeng Cui, Jacek Czepiel, Fabrizio D’Acapito, Dimitrios Damaskos, Koray Daş, Belinda De Simone, Samir Delibegović, Zaza Demetrashvili, Džemail Detanac, Sameer Dhingra, Stefano Di Bella, Evgeni Dimitrov, Agron Dogjani, Mario D’Oria, Irina Magdalena Dumitru, Mutasim M. Elmangory, Octavian Enciu, Massimo Fantoni, Daniela Filipescu, Francesco Fleres, Domitilla Foghetti, Pietro Fransvea, Mahir Gachabayov, Rita Galeiras, Gianni Gattuso, Wagih Ghannam, Valeria Ghisetti, Giorgio Giraudo, Kebebe Bekele Gonfa, Emre Gönüllü, Yousif Tag Elsir Y. Hamad, Matthias Hecker, Arda Işık, Nizar Ismail, Azzain Ismail, Sumita Jain, Souha S. Kanj, Garima Kapoor, Ilias Karaiskos, Alfie J. Kavalakat, Jakub Kenig, Faryal Khamis, Vladimir Khokha, Ronald Kiguba, Jae Il Kim, Yoshiro Kobe, Kenneth Yuh Yen Kok, Bojan Kovačević, І. А. Кryvoruchko, Akira Kuriyama, Aitor Landaluce-Olavarria, Konstantinos Lasithiotakis, Varut Lohsiriwat, Eftychios Lostoridis, Davide Luppi, Gustavo M. Machaín, Marc Maegele, Athanasios Marinis, Gennaro Martines, Aleix Martínez‐Pérez, Damien Massalou, Cristian Meşină, Gökhan Metan, Marı́a Guadalupe Miranda-Novales, Shyam Kumar Mishra, Mohaned Ibrahim Hussein Mohamed, Ali Yasen Mohamedahmed, Ismael Mora‐Guzmán, Francesk Mulita, Ana-Maria Muşină, Pradeep H. Navsaria, Ionuţ Negoi, Gabriela Nita, Donal B O’Connor, Carlos A. Ordóñez, D Pantalone, Arpád Panyko, Aristeidis Papadopoulos, Νικόλαος Παραράς, Francesco Pata, Tapan Patel, Gianluca Pellino, Teresa Perra, Gennaro Perrone, Antonio Pesce, Tadeja Pintar, Georgi Popivanov, Alberto Porcu, Martha Quiodettis, Razrim Rahim, Ashrarur Rahman Mitul, Martin Reichert, Miran Rems, Glendee Yolande Reynolds Campbell, Nuno Rocha-Pereira, Gabriel Rodrigues, Gustavo Eduardo Roncancio Villamil, Stefano Rossi, Ibrahima Sall, Hossein Samadi Kafil, Diego Sasia, Jeremiah Seni, Charalampos Seretis, Mario Serradilla‐Martín, Vishal G. Shelat, Boonying Siribumrungwong, Mihail Slavchev, Leonardo Solaini, Boun Kim Tan, Antonio Tarasconi, Dario Tartaglia, Elena Toma, Gia Tomadze, Adriana Toro, Marcos Roberto Tovani‐Palone, Harry van Goor, A Vasilescu, András Vereczkei, Massimiliano Veroux, Sergio Alberto Weckmann, Lukas Werner Widmer, AliIbrahim Yahya, Sanoop Koshy Zachariah, Andee Dzulkarnaen Zakaria, Nadezhda Zubareva, Wietse P. Zuidema, Isidoro Di Carlo, Francesco Cortese, Gian Luca Baiocchi, Ronald V. Maier, Fausto Catena,
The objectives of the study were to investigate the organizational characteristics of acute care facilities worldwide in preventing and managing infections in surgery; assess participants' perception regarding infection prevention and control (IPC) measures, antibiotic prescribing practices, and source control; describe awareness about the global burden of antimicrobial resistance (AMR) and IPC measures; and determine the role of the Coronavirus Disease 2019 pandemic on said awareness.A cross-sectional ...
Tópico(s): Patient Satisfaction in Healthcare
2022 - BioMed Central | World Journal of Emergency Surgery
Mari Niemi, Juha Karjalainen, Rachel G. Liao, Benjamin M. Neale, Mark J. Daly, Andrea Ganna, Gita A. Pathak, Shea J. Andrews, Masahiro Kanai, Kumar Veerapen, Israel Fernández‐Cadenas, Eva C. Schulte, Pasquale Striano, M. Marttila, Camelia C. Minică, Eirini Marouli, Mohd Anisul Karim, Frank R. Wendt, Jeanne E. Savage, Laura Sloofman, Guillaume Butler‐Laporte, Han‐Na Kim, Stavroula Kanoni, Yukinori Okada, Jinyoung Byun, Younghun Han, Mohammed Jashim Uddin, George Davey Smith, Cristen J. Willer, Joseph D. Buxbaum, Juha Mehtonen, Hilary K. Finucane, Mattia Cordioli, Alicia R. Martin, Wei Zhou, Bogdan Paşaniuc, Hanna Julienne, Hugues Aschard, Huwenbo Shi, Loïc Yengo, Renato Polimanti, Maya Ghoussaini, Jeremy Schwartzentruber, Ian Dunham, Karolina Chwiałkowska, Margherita Francescatto, Amy Trankiem, Mary K. Balaconis, Lea K. Davis, Sulggi A. Lee, James R. Priest, Alessandra Renieri, Vijay G. Sankaran, David A. van Heel, Patrick Deelen, J. Brent Richards, Tomoko Nakanishi, Les Biesecker, V. Eric Kerchberger, J. Kenneth Baillie, Francesca Mari, Anna Bernasconi, J. Kenneth Baillie, Arif Canakoglu, Brooke N. Wolford, Annika Faucon, Atanu Kumar Dutta, Claudia Schurmann, Emi N. Harry, Ewan Birney, Huy Nguyen, Jamal Nasir, Mari Kaunisto, Matthew Solomonson, Nicole Dueker, Nirmal Vadgama, Sophie Limou, Souad Rahmouni, Hamdi Mbarek, Dima Darwish, Md Mesbah Uddin, Raquel Albertos, Jordi Pérez‐Tur, Ruolin Li, Lasse Folkersen, Ida Moltke, Nils Koelling, Alexander Teumer, Athanasios Kousathanas, Alicia Utrilla, Ricardo A. Verdugo, Ruth Zárate, Carolina Medina‐Gómez, David Gómez-Cabrero, Elena Carnero‐Montoro, Carmen L. Cadilla, Andrés Moreno‐Estrada, Adriana Garmendia, Leire Moya, Bahareh Sedaghati-khayat, Palwendé Romuald Boua, Marie-Julie Favé, Laurent C. Francioli, Audrey Lemaçon, Isabelle Migeotte, Sanjay Patel, Réka Várnai, József Szentpéteri, Csilla Sipeky, Francesca Colombo, Kathrin von Hohenstaufen, Píetro Lió, Costanza L. Vallerga, Qingbo Wang, Yosuke Tanigawa, Hogune Im, Chulho Han, Han Song, Jiwoo Lim, Y.‐A. Lee, Sugyeong Kim, Sangyoon Im, Biljana Atanasovska, Hajar Fauzan Ahmad, Cindy G. Boer, Philip R. Jansen, Lude Franke, Elżbieta Kaja, Dorota Pasko, Ingrid Kennis-Szilagyi, Sergey A. Kornilov, Vid Prijatelj, Ivana Nedeljković, Ilangkumaran Sivanadhan, Sarala Perumal, Sahar Esmaeeli, Nathaniel M. Pearson, Adam Auton, Janie F. Shelton, Anjali J. Shastri, Teresa Filshtein-Sonmez, Daniella Coker, Antony Symons, Jorge Esparza-Gordillo, Stella Aslibekyan, Jared O’Connell, Chelsea Ye, Catherine H. Weldon, Minoli A. Perera, Kevin J. O’Leary, Matthew Tuck, Travis J. O’Brien, David Meltzer, Peter H. O’Donnell, Edith A. Nutescu, Guang Yang, Cristina Alarcón, Stefanie Herrmann, Sophia Mazurek, Jeff Banagan, Zacharia Hamidi, April Barbour, Noora Raffat, Diana Moreno, Paula N. Friedman, Bart Ferwerda, Diederik van de Beek, Matthijs C. Brouwer, Alexander P. J. Vlaar, W. Joost Wiersinga, Daniëlle Posthuma, Elleke Tissink, Aeliko Zwinderman, Emil Uffelmann, Michiel A. van Agtmael, Anne Geke Algera, Frank van Baarle, Diane Bax, Martijn Beudel, Harm Jan Bogaard, Marije K. Bomers, Peter I. Bonta, Lieuwe D. J. Bos, Michela Botta, Justin de Brabander, Godelieve de Bree, Sanne de Bruin, Marianna Bugiani, Esther Bulle, Osoul Chouchane, Alex Cloherty, Dave A. Dongelmans, Paul Elbers, Lucas M. Fleuren, Suzanne E. Geerlings, Bart F. Geerts, Teunis B. H. Geijtenbeek, Armand R. J. Girbes, Abraham Goorhuis, Martin P. Grobusch, Florianne Hafkamp, Laura A. Hagens, Jörg Hamann, Vanessa Harris, Robert Hemke, Sabine Hermans, Leo Heunks, Markus W. Hollmann, Janneke Horn, Joppe W. Hovius, Menno D. de Jong, Rutger Koning, Niels van Mourik, Jeannine F. Nellen, Esther J. Nossent, Frederique Paulus, Edgar Peters, Tom van der Poll, Bennedikt Preckel, Jan M. Prins, Jorinde Raasveld, Tom D. Y. Reijnders, Michiel Schinkel, Marcus J. Schultz, Alex R. Schuurman, Kim Sigaloff, Marry R. Smit, Cornelis Stijnis, Willemke Stilma, Charlotte E. Teunissen, Patrick Thoral, Anissa M. Tsonas, Marc van der Valk, Denise P. Veelo, Heder de Vries, Michèle van Vugt, Dorien Wouters, René Minnaar, Adrie Kromhout, Kees W. J. van Uffelen, Ruud A. Wolterman, Genevieve Roberts, Daniel J. Park, Catherine A. Ball, Marie V. Coignet, Shannon McCurdy, Spencer C. Knight, Raghavendran Partha, Brooke Rhead, Miao Zhang, Nathan Berkowitz, Michael Gaddis, Keith Noto, Luong Ruiz, Miloš Pavlović, Eurie L. Hong, Kristin A. Rand, Ahna R. Girshick, Harendra Guturu, Asher Haug Baltzell, Souad Rahmouni, Julien Guntz, Y Beguin, Sara Pigazzini, Lindokuhle Nkambule, Youssef Bouysran, Adeline Busson, Xavier Peyrassol, Françoise Wilkin, Bruno Pichon, Guillaume Smits, Isabelle Vandernoot, Jean‐Christophe Goffard, Michel Georges, Michel Moutschen, Benoît Misset, Gilles Darcis, Julien Guiot, Laurent Jadot, Samira Azarzar, Patricia Dellot, Stéphanie Gofflot, Sabine Claassen, Axelle Bertrand, Gilles Parzibut, Mathilde Clarinval, Catherine Moermans, Olivier Malaise, Kamilia El Kandoussi, Raphaël Thonon, Pascale Huynen, Alyssia Mesdagh, Sofia Ferreira Melo, Nicolas Jacques, Emmanuel Di Valentin, François Giroule,
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed ...
Nature Portfolio
Stéphanie Bibert, Nicolas Guex, João Lourenço, Thomas Brahier, Matthaios Papadimitriou‐Olivgeris, Lauro Damonti, Oriol Manuel, Robin Liechti, Lou Götz, Jonathan Tschopp, Mathieu Quinodoz, Péter Vollenweider, Jean‐Luc Pagani, Mauro Oddo, Olivier Hügli, Frédéric Lamoth, Véronique Erard, Cathy Voide, Mauro Delorenzi, Nathalie Rufer, Fabio Candotti, Carlo Rivolta, Noémie Boillat‐Blanco, Pierre‐Yves Bochud,
The reason why most individuals with COVID-19 have relatively limited symptoms while other develop respiratory distress with life-threatening complications remains unknown. Increasing evidence suggests that COVID-19 associated adverse outcomes mainly rely on dysregulated immunity. Here, we compared transcriptomic profiles of blood cells from 103 patients with different severity levels of COVID-19 with that of 27 healthy and 22 influenza-infected individuals. Data provided a complete overview of ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Frontiers Media | Frontiers in Immunology
Cristina Meazza, Chiara Gertosio, Roberta Giacchero, Sara Pagani, Mauro Bozzola,
Referral for an assessment of tall stature is less common than for short stature. Tall stature is defined as a height more than two standard deviations above the mean for age. The majority of subjects with tall stature show a familial tall stature or a constitutional advance of growth (CAG), which is a diagnosis of exclusion. After a careful physical evaluation, tall subjects may be divided into two groups: tall subjects with normal appearance and tall subjects with abnormal appearance. In the case ...
Tópico(s): Connective tissue disorders research
2017 - BioMed Central | The Italian Journal of Pediatrics/Italian journal of pediatrics
Luca Beverina, G. Pagani, Mauro Sassi,
Organic electrochromic materials have gained constantly increasing interest over the years with respect to their inorganic counterpart due to essentially two distinctive characteristics: their processability through solution based low cost processes and their wide colour palette. Such characteristic features enabled their application in displays, smart windows, electronic paper and ophthalmic lenses. Alongside the established concept of donor-acceptor polymers, side chain functionalized multichromophoric ...
Tópico(s): Polyoxometalates: Synthesis and Applications
2014 - Royal Society of Chemistry | Chemical Communications
Elena Bozzola, Cristina Meazza, Marica Arvigo, P. Travaglino, Sara Pagani, Mauro Stronati, Antonella Gasparoni, Carolina Bianco, Mauro Bozzola,
The control of growth and nutritional status in the foetus and neonate is a complex mechanism, in which also hormones produced by adipose tissue, such as adiponectin and leptin are involved. The aim of this study was to evaluate levels of adiponectin, leptin and insulin in appropriate (AGA) and small for gestational age (SGA) children during the 1st year of life and to correlate these with auxological parameters.In 33 AGA and 29 SGA infants, weight, length, head circumference, glucose, insulin, adiponectin ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2010 - BioMed Central | The Italian Journal of Pediatrics/Italian journal of pediatrics
Luca Beverina, Riccardo Ruffο, C.M. Mari, G. Pagani, Mauro Sassi, Filippo De Angelis, Simona Fantacci, Jun‐Ho Yum, Michaël Grätzel, Mohammad Khaja Nazeeruddin,
Forward from square one: The incorporation of a molecularly engineered original panchromatic squaraine sensitizer in a dye-sensitized solar cell enables the preparation of devices having external quantum efficiencies as high as 4.71 %; an unprecedented result for this class of compounds. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please ...
Tópico(s): Polyoxometalates: Synthesis and Applications
2009 - Wiley | ChemSusChem
Franca Pagani, Mauro Panteghini,
5′-Nucleotidase (5′-ribonucleotide phosphohydrolase; EC 3.1.3.5; 5NT), an intrinsic membrane glycoprotein present as an ectoenzyme in a wide variety of mammalian cells, hydrolyzes 5′-nucleotides to their corresponding nucleosides (1). Despite its ubiquitous distribution, serum concentrations of 5NT appear to reflect hepatobiliary disease with considerable specificity (2). Dixon and Purdom (3) first observed that serum 5NT was clinically useful for differential diagnosis of hepatobiliary and osseous ...
Tópico(s): Viral gastroenteritis research and epidemiology
2001 - American Association for Clinical Chemistry | Clinical Chemistry
Marzia Bonato, Michele Cerati, Alberto Pagani, Mauro Papotti, Federica Bosi, Gianni Bussolati, Carlo Capella,
Tópico(s): Neuroblastoma Research and Treatments
1992 - Springer Science+Business Media | Virchows Archiv A Pathological Anatomy and Histopathology
Alberto Pagani, Mauro Papotti, B Sanfilippo, Gianni Bussolati,
Expression of gastrin-releasing peptide (GRP), the mammalian homologue of the amphibian bombesin, has been investigated at gene and protein level in a series of 28 primary breast carcinomas, in 6 mammary cancer cell lines and in one transplantable rat mammary carcinoma. Moderate to strong expression of GRP mRNA was detected in 5 breast carcinomas by Northern blot analysis with a pre-pro-GRP probe; 4 other cases were weakly reactive. Two of these cases also gave a specific immunocytochemical reaction ...
Tópico(s): Neuroendocrine Tumor Research Advances
1991 - Wiley | International Journal of Cancer
Franca Pagani, Mauro Panteghini,
Analytical, within-subject, and between-subject components of variability have beeh determined for total cholesterol, LDL-cholesterol, HDL-cholesterol, and its HDL2 and HDL3 subfractions, triglycerides, apolipoproteins A-1 and B, and lipoprotein(a) in serum specimens from a cohort of 10 healthy subjects over a 1-month period. From these data, we have calculated the desirable analytical imprecisions, the indices of individuality, the critical differences for significant change detection, and the ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
1993 - Elsevier BV | Clinical Biochemistry
James P. Sur, Francis D. Pagani, Mauro Moscucci,
The use of the Tandem Heart percutaneous ventricular assist device (Tandem Heart pVAD, Cardiac Assist technologies, Pittsburgh, PA) as a bridge to recovery or to other cardiopulmonary support systems has been rising. One requirement for placement of this device is an intraatrial septostomy which is usually closed during the surgical insertion of more permanent ventricular assist devices. We present a case of a 62-year-old man with a residual acquired atrial septal defect (ASD) from Tandem Heart placement, ...
Tópico(s): Congenital Heart Disease Studies
2008 - Wiley | Catheterization and Cardiovascular Interventions
Patrizia Bonadonna, Roberta Zanotti, Mauro Pagani, Massimiliano Bonifacio, Luigi Scaffidi, Elisa Olivieri, Maurizio Franchini, Federico Reccardini, Maria Teresa Costantino, Chiara Roncallo, Marina Mauro, Elisa Boni, Fabio Lodi Rizzini, Maria Beatrice Bilò, Anna Rosaria Marcarelli, Giovanni Passalacqua,
Background Up to 75% of patients with severe anaphylactic reactions after Hymenoptera sting are at risk of further severe reactions if re-stung. Venom immunotherapy (VIT) is highly effective in protecting individuals with ascertained Hymenoptera venom allergy (HVA) and previous severe reactions. After a 3- to 5-year VIT course, most patients remain protected after VIT discontinuation. Otherwise, a lifelong treatment should be considered in high-risk patients (eg, in mastocytosis). Several case reports evidenced ...
Tópico(s): Allergic Rhinitis and Sensitization
2017 - Elsevier BV | The Journal of Allergy and Clinical Immunology In Practice
Raffaello Furlan, Wilma Crivellaro, Simonetta DellʼOrto, Elisa Gentile, S. Piazza, Maria R. Pagani, Mauro Tinelli, S. Cerutti, Federico Lombardi, Massimo Pagani, Alberto Malliani,
In 10 ambulant subjects we studied the circadian changes in sympathetic vasomotor control as assessed by the spectral power of the 0.1-Hz low-frequency component of systolic arterial pressure variability measured with a Millar phi 3F tip transducer. The low-frequency component was higher during the daytime, while the subjects were performing light physical activity, and lower during the night, thus paralleling the circadian systolic blood pressure pattern. However, the morning low-frequency rise ...
Tópico(s): Circadian rhythm and melatonin
1989 - Lippincott Williams & Wilkins | Journal of Hypertension
A. Barbaud, Lene H. Garvey, Alessandra Arcolacı, Knut Brockow, Francesca Mori, Cristobalina Mayorga, Patrizia Bonadonna, Marina Atanasković‐Marković, Luis Moral, Giovanna Zanoni, Mauro Pagani, A. Soria, Maja Jošt, Jean‐Christoph Caubet, Abreu Carmo, Mona Al‐Ahmad, Alberto Álvarez‐Perea, Sevim Bavbek, Benedetta Biagioni, Maria Beatrice Bilò, Natalia Blanca‐López, Herrera Gádor Bogas, Alessandro Buonomo, Gianfranco Calogiuri, G Carli, Josefina Cernadas, Gabriele Cortellini, Gülfem Çelík, Semra Demir, Inmaculada Doña, Adile Berna Dursun, Bernadette Eberlein, Emília Faria, Bryan Fernandes, Tomaz Garcez, I García-Núñez, Radosław Gawlik, Aslı Gelincik, Eva Gomes, J. Gooi, Martine Grosber, Theo Gülen, F. Hacard, Cyrille Hoarau, Christer Janson, Sebastian L. Johnston, Lukas Joerg, Seçil Kepil Özdemir, Ludger Klimek, Mitja Košnik, Marek L. Kowalski, Semanur Kuyucu, Violeta Kvedarienė, José Julio Laguna, Carla Lombardo, Susana Marinho, Hans F. Merk, Elisa Meucci, M. Morisset, Rosa Muñoz‐Cano, F Murzilli, Alla Nakonechna, Florin‐Dan Popescu, Grzegorz Porębski, Anna Radice, Frederico S. Regateiro, Heike Röckmann, Antonino Romano, Ravishankar Sargur, J. Sastre, Kathrin Scherer Hofmeier, Lenka Sedlačková, Marta Sobotková, Ingrid Terreehorst, Regina Treudler, Jolanta Walusiak‐Skorupa, Bettina Wedi, Stefan Wöhrl, Mihael Zidarn, Torsten Zuberbier, Ioana Agache, Marı́a José Torres,
Anaphylaxis, which is rare, has been reported after COVID-19 vaccination, but its management is not standardized.Members of the European Network for Drug Allergy and the European Academy of Allergy and Clinical Immunology interested in drug allergy participated in an online questionnaire on pre-vaccination screening and management of allergic reactions to COVID-19 vaccines, and literature was analysed.No death due to anaphylaxis to COVID-19 vaccines has been confirmed in scientific literature. Potential ...
Tópico(s): Food Allergy and Anaphylaxis Research
2022 - Wiley | Allergy
Massimo Franchini, Claudia Glingani, Mario Morandi, Giovanni Corghi, Sara Cerzosimo, Gloria Beduzzi, Andrea Ennio Storti, Vincenza Di Stasi, Giulia Rastrelli, Linda Vignozzi, Carlo Mengoli, Martina Garuti, Massimiliano Beccaria, Francesco Inglese, Beatrice Caruso, Roberto Antonio Petilino, Massimo Amato, Michele Nicchio, Mauro Pagani, Angela Bellani, Gianpaolo Castelli, Salvatore Casari, Giuseppe De Donno,
ObjectiveTo assess the safety and efficacy of convalescent plasma (CP) transfusion in elderly people with moderate to severe coronavirus disease 2019 (COVID-19) living in a long-term care facility (LTCF).Patients and MethodsTwenty-two consecutive elderly patients with COVID-19 infection living in an LTCF in Lombardy, Italy, who were given CP during May 15 to July 31, 2020, were enrolled in a prospective cohort study. Their clinical, instrumental, and laboratory parameters were assessed following the ...
Tópico(s): COVID-19 and Mental Health
2021 - Elsevier BV | Mayo Clinic Proceedings Innovations Quality & Outcomes
Neutrophil extracellular traps (NETs) are net-like chromatin fibers that are released from dying neutrophils during infections. NETs are a sort of scaffold, ideal to retain microbes. The main function of NETs is the trapping and killing pathogens, as such as bacteria, fungi, viruses (including SARS-CoV-2) and protozoa. The death of neutrophils via NETs formation is called "NETosis." Nevertheless, recent studies suggest that NETosis is involved in several diseases, other than infections. Very recently, ...
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2021 - Elsevier BV | Current Problems in Cardiology
Sevim Bavbek, Mauro Pagani, Emilio Alvarez‐Cuesta, Mariana Castells, Adile Berna Dursun, Sahar Hamadi, Ricardo Madrigal‐Burgaleta, Soledad Sanchez‐Sanchez, Alessandra Vultaggio,
Biologicals are crucial targeted therapeutic agents in oncological, immunological, and inflammatory diseases, and their use in clinical practice is broadening. In recent years, the spread of Personalized Precision Medicine has facilitated a proliferation of new treatment options, especially biologicals. Consequently, biologicals are now among the drugs that most frequently cause hypersensitivity reactions (HSRs). Patients can develop HSRs to these agents during the first-lifetime exposure or after ...
Tópico(s): Biosimilars and Bioanalytical Methods
2021 - Wiley | Allergy
Mauro Pagani, Sevim Bavbek, Emilio Alvarez‐Cuesta, Adile Berna Dursun, Patrizia Bonadonna, Mariana Castells, Josefina Cernadas, Anca Mirela Chiriac, H Ahmed Sahar, Ricardo Madrigal‐Burgaleta, Soledad Sanchez Sanchez,
Chemotherapeutic drugs have been widely used in the treatment of cancer disease for about 70 years. The development of new treatments has not hindered their use, and oncologists still prescribe them routinely, alone or in combination with other antineoplastic agents. However, all chemotherapeutic agents can induce hypersensitivity reactions (HSRs), with different incidences depending on the culprit drug. These reactions are the third leading cause of fatal drug-induced anaphylaxis in the United States. ...
Tópico(s): Urticaria and Related Conditions
2021 - Wiley | Allergy
Massimo Franchini, Claudia Glingani, Giuseppe De Donno, Salvatore Casari, Beatrice Caruso, Isabella Terenziani, Cesare Perotti, Claudia Del Fante, Filippo Sartori, Mauro Pagani,
Acquired hemophilia A (AHA) is a rare bleeding disorder caused by circulating autoantibodies directed against clotting factor VIII (FVIII).1, 2 It involves more frequently elderly people with no previous personal or family history of bleeding. Approximately half of patients with AHA do not have underlying or predisposing disorders (idiopathic cases), with the remaining cases being associated with a wide array of conditions or diseases (ie, post-partum, autoimmune and dermatologic disorders, malignancies, ...
Tópico(s): Chronic Myeloid Leukemia Treatments
2020 - Wiley | American Journal of Hematology
Mauro Pagani, Sevim Bavbek, Adile Berna Dursun, Patrizia Bonadonna, María Elisa Caralli, Josefina Cernadas, Gabriele Cortellini, Maria Teresa Costantino, Aslı Gelincik, Giuseppe Lucchini, Mariana Castells,
Immediate hypersensitivity reactions (HSRs) to taxanes have been increasing in recent years, but the importance of skin tests in allergological workup has not been established.In our study we tried to evaluate the role of prick and intradermal tests in the diagnosis of HSRs to paclitaxel and docetaxel.In this multicenter prospective study, we enrolled patients with immediate HSRs to the aforesaid agents. Skin tests were performed on these subjects and if results were negative, intradermal tests with ...
Tópico(s): Pharmacovigilance and Adverse Drug Reactions
2018 - Elsevier BV | The Journal of Allergy and Clinical Immunology In Practice
Patrizia Bonadonna, Mauro Pagani, Werner Aberer, Maria Beatrice Bilò, Knut Brockow, Hanneke Oude Elberink, Lene H. Garvey, H. Mosbech, Antonino Romano, Roberta Zanotti, Marı́a José Torres,
Mastocytosis is a clonal disorder characterized by the proliferation and accumulation of mast cells (MC) in different tissues, with a preferential localization in skin and bone marrow (BM). The excess of MC in mastocytosis as well as the increased releasability of MC may lead to a higher frequency and severity of immediate hypersensitivity reactions. Mastocytosis in adults is associated with a history of anaphylaxis in 22-49%. Fatal anaphylaxis has been described particularly following hymenoptera ...
Tópico(s): Food Allergy and Anaphylaxis Research
2015 - Wiley | Allergy
Use of cytotoxic agents is associated with potential hypersensitivity reactions which are common with platinum compounds , L-asparaginase, taxanes, procarbazine and epipodophyllotoxins . Mechanisms underlying the reactions may involve IgE, non-allergic or a number of pathogenetically unclear events. Targeted therapies produce less collateral damage but demonstrate their own unique reactions. Cytopenias occur less often and mucocutaneous reactions to EGFR inhibitors , including papulopustular rash, are ...
Tópico(s): Chronic Myeloid Leukemia Treatments
2014 - Elsevier BV | Immunology and Allergy Clinics of North America
Knut Brockow, L Garvey, Werner Aberer, Marina Atanasković‐Marković, A. Barbaud, Maria Beatrice Bilò, Andreas J. Bircher, M. Blanca, B. Bonadonna, Paolo Campi, Eunice Dias de Castro, J. R. Cernadas, A.M. Chiriac, P. Démoly, Martine Grosber, J. Gooi, Carla Lombardo, P.-M. Mertes, H. Mosbech, Shuaib Nasser, Mauro Pagani, Johannes Ring, Antonino Romano, Kathrin Scherer Hofmeier, Benno Schnyder, Sergio Testi, Marı́a José Torres, Axel Trautmann, Ingrid Terreehorst,
Abstract Skin tests are of paramount importance for the evaluation of drug hypersensitivity reactions. Drug skin tests are often not carried out because of lack of concise information on specific test concentrations. The diagnosis of drug allergy is often based on history alone, which is an unreliable indicator of true hypersensitivity.To promote and standardize reproducible skin testing with safe and nonirritant drug concentrations in the clinical practice, the E uropean N etwork and E uropean ...
Tópico(s): Food Allergy and Anaphylaxis Research
2013 - Wiley | Allergy
Mauro Pagani, Lennart Venemalm, P. Bonnadona, Pier Paolo Vescovi, C. Botelho, Josefina Cernadas,
Carboplatin, a second-generation platinum compound, is a chemotherapeutic drug effective in many types of cancers. Its use is limited by the development of systemic allergic reactions in up to 30% of the cancer patients. Therefore, it is very important to make a correct diagnosis of true carboplatin allergy, for the crucial clinical implications. In this regard, no biological test is actually available to detect specific immunoglobulin E in the sera of patients allergic to carboplatin. We evaluated ...
Tópico(s): Contact Dermatitis and Allergies
2012 - Oxford University Press | Japanese Journal of Clinical Oncology
Livio Simioni, A. Vianello, Patrizia Bonadonna, G Marcer, Maurizio Severino, Mauro Pagani, Luca Morlin, Mariangiola Crivellaro, Giovanni Passalacqua,
Standard venom immunotherapy involves the administration of the maintenance dose every 4 to 6 weeks. This regimen may have adherence problems, especially in the long term; thus, extended intervals have been proposed.We prospectively compared the efficacy of 3- or 4-month extended maintenance dose vs the conventional regimen.Patients receiving immunotherapy with a single venom were offered the extended maintenance dose (EMD) and were then followed up for field re-stings. Only the re-stings by the ...
Tópico(s): Food Allergy and Anaphylaxis Research
2012 - Elsevier BV | Annals of Allergy Asthma & Immunology
Patrizia Bonadonna, Carla Lombardo, Oscar Bortolami, Andreas J. Bircher, Kathrin Scherer Hofmeier, A. Barbaud, Giovanni Passalacqua, Mauro Pagani,
Proton pump inhibitors (PPIs) are widely used for the treatment of acid-related gastrointestinal diseases because they reduce the gastric acid secretion by blocking the H+/K+-ATPase. PPIs include omeprazole, lansoprazole, rabeprazole, pantoprazole, and esomeprazole. PPIs are generally well tolerated, and side effects occur in about 1% of the patients.1 Hypersensitvity reactions are also rare, but several reports have described anaphylaxis, urticaria, or asthma.2-5 The diagnosis of hypersensitivity ...
Tópico(s): Asthma and respiratory diseases
2012 - Elsevier BV | Journal of Allergy and Clinical Immunology