Produção Nacional
Revisado por pares
Ariane Coelho Ferraz, Letícia Trindade Almeida, Camila Carla da Silva Caetano, Marília Bueno da Silva Menegatto, Rafaela Lameira Souza Lima, Joao Pinto Nelson de Senna, Jamille Mirelle de Oliveira Cardoso, Luíza Oliveira Perucci, André Talvani, Wanderson Geraldo de Lima, Breno de Mello Silva, Alexandre Barbosa Reis, José Carlos de Magalhães, Cíntia Lopes de Brito Magalhães,
Infection caused by Mayaro virus (MAYV) is responsible for causing acute nonspecific fever, in which the majority of patients develop incapacitating and persistent arthritis/arthralgia. Mayaro fever is a neglected and underreported disease without treatment or vaccine, which has gained attention in recent years after the competence of Aedes aegypti to transmit MAYV was observed in the laboratory, coupled with the fact that cases are being increasingly reported outside of endemic forest areas, calling ...
Tópico(s): Research on Leishmaniasis Studies
2021 - Elsevier BV | Antiviral Research
Produção Nacional
Revisado por pares
Fernanda Caetano Camini, Camila Carla da Silva Caetano, Letícia Trindade Almeida, Joyce Ferreira da Costa Guerra, Breno de Mello Silva, Silvana de Queiroz Silva, José Carlos de Magalhães, Cíntia Lopes de Brito Magalhães,
Mayaro virus (MAYV) is a neglected tropical arbovirus that causes a febrile syndrome that is sometimes accompanied by incapacitating arthritis/arthralgia. The pathogenesis of MAYV has not been completely defined and oxidative stress mediated by an increase in reactive oxygen species (ROS) and/or depletion of antioxidant defences has been found to contribute to several aspects of viral disease. To investigate whether MAYV induced oxidative stress in host cells, we monitored ROS production, oxidative ...
Tópico(s): Intimate Partner and Family Violence
2017 - Elsevier BV | Virus Research
Produção Nacional
Revisado por pares
Fernanda Caetano Camini, Tales Fernando da Silva, Camila Carla da Silva Caetano, Letícia Trindade Almeida, Ariane Coelho Ferraz, Verônica Maria Alves Vitoreti, Breno de Mello Silva, Silvana de Queiroz Silva, José Carlos de Magalhães, Cíntia Lopes de Brito Magalhães,
Mayaro virus (MAYV) is a neglected arbovirus belonging to the family Togaviridae. Its infection leads to Mayaro fever, with clinical manifestations such as fever, myalgia, headache, rash, arthralgia, vomiting, and diarrhea. The most prominent complaint from infected person is the long-lasting arthritis/arthralgia. The treatment for Mayaro fever is mainly symptom-based and there are no vaccines or antiviral drugs currently available, thus, natural products with anti-MAYV activity may provide a potential ...
Tópico(s): Malaria Research and Control
2018 - Elsevier BV | Antiviral Research
Produção Nacional
Revisado por pares
Camila Carla da Silva Caetano, Fernanda Caetano Camini, Letícia Trindade Almeida, Ariane Coelho Ferraz, Tales Fernando da Silva, Rafaela Lameira Souza Lima, Mayara Medeiros de Freitas Carvalho, Thalles de Freitas Castro, Cláudia Martins Carneiro, Breno de Mello Silva, Silvana de Queiroz Silva, José Carlos de Magalhães, Cíntia Lopes de Brito Magalhães,
Mayaro virus (MAYV) causes Mayaro fever in humans, a self-limiting acute disease, with persistent arthralgia and arthritis. Although MAYV has a remerging potential, its pathogenic mechanisms remain unclear. Here, we characterized a model of MAYV infection in 3-4-week BALB/c mice. We investigated whether the liver acts as a site of viral replication and if the infection could cause histopathological alterations and an imbalance in redox homeostasis, culminating with oxidative stress. MAYV-infected ...
Tópico(s): Viral Infections and Outbreaks Research
2019 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Maria Karolaynne da Silva, Arthur Antunes Coimbra Azevedo, Daniel Melo de Oliveira Campos, Janeusa Trindade de Souto, U. L. Fulco, Jonas Ivan Nobre Oliveira,
Mayaro virus (MAYV) is an arbovirus found in the Americas that can cause debilitating arthritogenic disease. Although ...
Tópico(s): Invertebrate Immune Response Mechanisms
2022 - Taylor & Francis | Journal of Biomolecular Structure and Dynamics
Gabriele Louise Trindade Araújo, P. R. Queiroz,
... se citar: Chikungunya, Dengue, Febre Amarela, Febre do Mayaro, Zika e Febre do Oeste do Nilo. Essas ...
Tópico(s): Fish biology, ecology, and behavior
2022 - | Programa de Iniciação Científica - PIC/UniCEUB - Relatórios de Pesquisa
Produção Nacional
Alex da S. Bocaleti, Valtir Y. T. de Almeida, Eduarda A. de Lima, Renan R. Schorr, Francisco de Assis Marques, Mário Antônio Navarro-Silva, Gislayne Trindade Vilas-Bôas, João Antônio Cyrino Zequi,
... Valley fever, Saint Louis encephalitis, Zika virus and Mayaro virus. Subsequent monitoring and control of these vectors ...
Tópico(s): Insect Pest Control Strategies
2024 - | BioAssay