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Carta Acesso aberto Revisado por pares

Assumpta Ferrer, Teresa Badía, Francesç Formiga, Héctor Sanz, Maria Jesus Megido, Ramón Pujol,

... ABS Sant Andreu de la Barca), M.J. Megido (ABS Just Oliveras), G. Padrós (Laboratori Clínic L' ... Sanz conducted statistical analysis and reviewed the manuscript. Megido reviewed the manuscript. Pujol reviewed the manuscript. Sponsor' ...

Tópico(s): Health Systems, Economic Evaluations, Quality of Life

2013 - Wiley | Journal of the American Geriatrics Society

Artigo Revisado por pares

Amit Gefen, M. Megido-Ravid, Y Itzchak, M. Arcan,

Plantar pressure measurements and surface electromyography (EMG) were used to determine the effects of muscular fatigue induced by high-heeled gait. The medio-lateral (M/L) stability of the foot was characterized by measuring the M/L deviations of the center of pressure (COP) and correlating these data with fatigue of lower-limb muscles seen on EMG. EMG measurements from habitual high-heeled shoe wearers demonstrated an imbalance of gastrocnemius lateralis versus gastrocnemius medialis activity in ...

Tópico(s): Muscle activation and electromyography studies

2002 - Elsevier BV | Gait & Posture

Artigo Revisado por pares

María‐Victoria Mateos, Ramón García‐Sánz, Ricardo López‐Pérez, Marı́a Jesús Moro, Enrique M. Ocio, José‐Ángel Hernández‐Rivas, Marta Megido, Marı́a Dolores Caballero, Javier Fernández‐Calvo, Abelardo Bárez, Júlia Almeida, Alberto Órfão, Marcos González, Jesús F. San Miguel,

In order to gain further insights into the role of the p16 gene in cell cycle regulation and the prognostic implications of its inactivation, we investigated the methylation status of the p16 gene in 98 untreated patients using a polymerase chain reaction assay based on the inability of some restriction enzymes to digest methylated sequences. Forty-one patients showed a p16 methylated gene (42%). The percentage of S-phase plasma cells (PC) in these patients was almost three times higher than in those ...

Tópico(s): Cancer Genomics and Diagnostics

2002 - Wiley | British Journal of Haematology

Artigo Acesso aberto Revisado por pares

Adriana Armellini, María Eugenia Sarasquete, Ramón García‐Sánz, Carmen Chillón, Ana Balanzategui, Miguel Alcoceba, M. Fuertes, Rafael López‐López, Jesús María Hernández‐Rivas, Javier Fernández‐Calvo, Magdalena Sierra, M. Megido, Alberto Órfão, Norma C. Gutiérrez, Marcos González, Jesús F. San Miguel,

Summary RAN , ZHX2 and RCBTB2 ( CHC1L) expression was evaluated by quantitative real time reverse transcription polymerase chain reaction in plasma cells from 85 monoclonal gammopathies: 58 symptomatic multiple myeloma (MM) (52 untreated, six relapsed), eight smouldering MM, five monoclonal gammopathy of undetermined significance, four plasma cell leukaemias and 10 myeloid cell lines. ZHX2 was weakly expressed in high‐risk/proliferative disease compared to low‐risk or indolent disease. High ZHX2 expression ...

Tópico(s): Cancer-related gene regulation

2008 - Wiley | British Journal of Haematology

Artigo Acesso aberto Revisado por pares

Francesç Formiga, Assumpta Ferrer, Maria Jesus Megido, David Chivite, Teresa Badía, Ramón M. Pujol,

The population is aging throughout the world. Preserving physical and cognitive functions is crucial to successful aging. The aim of this study was to determine the proportion of 85-year-old community-dwelling subjects aging successfully, applying a quantitative approach, and assessing the association of successful aging with sociodemographic data, global geriatric assessment, and co-morbidity. This was a community-based survey of inhabitants aged 85 years, with 328 out of 487 subjects born in 1924 ...

Tópico(s): Health disparities and outcomes

2011 - Mary Ann Liebert, Inc. | Rejuvenation Research

Artigo Revisado por pares

Rudy Caparros Megido, Éric Haubruge, François Verheggen,

Tópico(s): Insect and Arachnid Ecology and Behavior

2012 - Springer Science+Business Media | Journal of Pest Science

Artigo Revisado por pares

Maryam Arefi, Juan Luis Garcı́a, María Jesús Peñarrubia, José Antonio Queizán, Lourdes Hermosín, Lucía López‐Corral, Marta Megido, Pilar Giraldo, Natalia de las Heras, Raúl Vanegas, Norma C. Gutiérrez, Jesús María Hernández‐Rivas,

The myeloproliferative neoplasms displaying a PDGFRB rearrangement are rare diseases derived from a haematopoietic stem cell. The goals of the study were to assess the incidence of these disorders and to define the clinical and biological characteristics as well as the response to the imatinib therapy.A total of 556 patients with myeloproliferative neoplasms were studied by means of molecular cytogenetics.The incidence of myeloproliferative neoplasms (MPN) with PDGFRB rearrangement was low (10 cases, ...

Tópico(s): Chronic Myeloid Leukemia Treatments

2012 - Wiley | European Journal Of Haematology

Artigo Revisado por pares

Y. Rotstein, Gaby Shaliv, Michael Rybakov,

... also evident. A marked zone of compression near Megido is associated with the intersection of the two ...

Tópico(s): Geological and Geochemical Analysis

2004 - Elsevier BV | Tectonophysics

Artigo Revisado por pares

Amit Gefen, M. Megido-Ravid, Y Itzchak, M. Arcan,

A novel three-dimensional numerical model of the foot, incorporating, for the first time in the literature, realistic geometric and material properties of both skeletal and soft tissue components of the foot, was developed for biomechanical analysis of its structural behavior during gait. A system of experimental methods, integrating the optical Contact Pressure Display (CPD) method for plantar pressure measurements and a Digital Radiographic Fluoroscopy (DRF) instrument for acquisition of skeletal ...

Tópico(s): Foot and Ankle Surgery

2000 - ASM International | Journal of Biomechanical Engineering

Artigo Acesso aberto Revisado por pares

Thomas Bawin, Lara De Backer, David Dujeu, Pauline Legrand, Rudy Caparros Megido, Frédéric Francis, François Verheggen,

The tomato leafminer, Tuta absoluta (Lepidoptera: Gelechiidae), is a devastating pest that develops principally on solanaceous plants throughout South and Central America and Europe. In this study, we tested the influence of three levels of T. absoluta infestations on the attraction and oviposition preference of adult T. absoluta. Three infestation levels (i.e., non-infested plants, plants infested with 10 T. absoluta larvae, and plants infested with 20 T. absoluta larvae) were presented by pairs ...

Tópico(s): Insect Pheromone Research and Control

2014 - Multidisciplinary Digital Publishing Institute | Insects

Artigo Revisado por pares

Francesç Formiga, Assumpta Ferrer, Maria Jesus Megido, Lucía Boix-Palop, Ana Contra, Ramón M. Pujol,

Poor vitamin D status, i.e. low serum levels of 25-hydroxyvitamin D [25(OH)D], is common in the general population. Prospective epidemiologic data on the association between vitamin D and mortality in oldest old subjects are limited.This study aimed to determine whether 25(OH)D concentrations were prospectively and independently associated with cardiovascular disease (CVD) mortality and all-cause mortality in oldest old subjects.A total of 312 subjects aged 85 years old at baseline (Octabaix study) ...

Tópico(s): Vitamin C and Antioxidants Research

2013 - Karger Publishers | Gerontology

Revisão Revisado por pares

Rudy Caparros Megido, Éric Haubruge, François Verheggen,

Synthese bibliographique : les strategies de lutte pheromonale utilisees pour controler la mineuse de la tomate, Tuta absoluta (Lepidoptera : Gelechiidae). Cette synthese bibliographique fait le point sur les strategies de lutte pheromonale developpees specifiquement pour lutter contre la mineuse de la tomate, Tuta absoluta (Lepidoptera: Gelechiidae). Ce ravageur provient d’Amerique du Sud et est actuellement considere comme un des plus importants ravageurs de tomates dans les pays europeens et nord- ...

Tópico(s): Insect and Pesticide Research

2013 - Presses Agronomiques de Gembloux | BASE

Artigo Revisado por pares

Rudy Caparros Megido, Yves Brostaux, Éric Haubruge, François Verheggen,

Tópico(s): Insect behavior and control techniques

2013 - Springer Science+Business Media | American Journal of Potato Research

Artigo Revisado por pares

Rudy Caparros Megido, Ludovic Sablon, Mélodie Geuens, Yves Brostaux, Taofic Alabi, Christophe Blecker, Didier Drugmand, Éric Haubruge, Frédéric Francis,

Abstract Entomophagy is not well accepted in W estern E uropean populations but it is common in the world. In the future, populations from developed countries should adapt to other sources of animal proteins because traditional breeding of beef, poultry or pork will become unsustainable. This study was performed to assess the perception of entomophagy in the B elgian population. A slight neophobia was detected but people agreed to evaluate insect preparations. Various insect formulations (mealworms ...

Tópico(s): Olfactory and Sensory Function Studies

2013 - Wiley | Journal of Sensory Studies

Artigo Revisado por pares

Amit Gefen, M. Megido-Ravid, Y Itzchak,

A technique is introduced for simultaneous measurements of the heel pad tissue deformation and the heel-ground contact stresses developing during the stance phase of gait. Subjects walked upon a gait platform integrating the contact pressure display optical method for plantar pressure measurements and a digital radiographic fluoroscopy system for skeletal and soft tissue motion recording. Clear images of the posterior-plantar aspect of the calcaneus and enveloping soft tissues were obtained simultaneously ...

Tópico(s): Foot and Ankle Surgery

2001 - Elsevier BV | Journal of Biomechanics

Artigo Revisado por pares

Amit Gefen, M. Megido-Ravid, M Biju Azariah, Y Itzchak, M. Arcan,

Objective. A method of measuring mechanical properties of plantar soft tissues in vivo by integrating a photoelastic technique into an MRI system is presented. Background. Plantar tissue stiffening in the diabetic foot is associated with development of ulcers at the highest-pressure sites. MRI is used as an effective means of demonstrating tissue damage caused by diabetic ulceration. Design. The new measurement method uses the indentation of a sphere into the plantar tissue, which is simultaneously ...

Tópico(s): Tendon Structure and Treatment

2001 - Elsevier BV | Clinical Biomechanics

Artigo Revisado por pares

Rudy Caparros Megido, Taofic Alabi, Clément Nieus, Christophe Blecker, Sabine Danthine, Jan Bogaert, Éric Haubruge, Frédéric Francis,

Abstract BACKGROUND The health status of the indigenous people of Ratanakiri Province, Cambodia, is significantly lower compared with that of the rest of the nation. The domestication and mass production of insects may represent a sustainable, cost effective and high quality alternative source of protein to traditional livestock. This study aimed to optimise a cheap and residential cricket breeding system based on unused wild resources. The development of crickets, Teleogryllus testaceus (Walker), ...

Tópico(s): Insect and Arachnid Ecology and Behavior

2015 - Wiley | Journal of the Science of Food and Agriculture

Artigo Revisado por pares

Assumpta Ferrer, Francesç Formiga, Oriol Cunillera, Maria Jesus Megido, Xavier Corbella, Jesús Almeda,

Tópico(s): Geriatric Care and Nursing Homes

2015 - Springer Science+Business Media | Quality of Life Research

Artigo Acesso aberto Revisado por pares

María Abáigar, Cristina Robledo, Rocí­o Benito, Fernando Ramos, María Díez‐Campelo, Lourdes Hermosín, Javier Sánchez‐del‐Real, José M. Alonso, Rebeca Cuello, Marta Megido, N. Rodríguez, Guillermo Martín–Núñez, Carlos Aguilar, Manuel Vargas, Ana A. Martín, Juan Luis Garcı́a, Alexander Kohlmann, M.C. del Cañizo, Jesús María Hernández‐Rivas,

To explore novel genetic abnormalities occurring in myelodysplastic syndromes (MDS) through an integrative study combining array-based comparative genomic hybridization (aCGH) and next-generation sequencing (NGS) in a series of MDS and MDS/myeloproliferative neoplasms (MPN) patients. 301 patients diagnosed with MDS (n = 240) or MDS/MPN (n = 61) were studied at the time of diagnosis. A genome-wide analysis of DNA copy number abnormalities was performed. In addition, a mutational analysis of DNMT3A, TET2, RUNX1, ...

Tópico(s): Myeloproliferative Neoplasms: Diagnosis and Treatment

2016 - Public Library of Science | PLoS ONE

Artigo Revisado por pares

Aman Paul, Michel Frédérich, Roel Uyttenbroeck, Priyanka Malik, Sandrino Filocco, Aurore Richel, Stéphanie Heuskin, Taofic Alabi, Rudy Caparros Megido, Thierry Franck, Jérôme Bindelle, Philippe Maesen, Frédéric Francis, Georges Lognay, Christophe Blecker, Éric Haubruge, Sabine Danthine,

Insects, particularly those belonging to the family Acrididae (grasshoppers), are commonly consumed as human food in many parts of the world. Grasshoppers of the species Chorthippus parallelus are abundantly found throughout Europe. However, these insects were not consumed by Europeans till now, but could possibly be used as human food, which is why we investigated their chemical composition. We found that they contain high level of proteins (69%), with an excellent amino acid profile and protein ...

Tópico(s): Neurobiology and Insect Physiology Research

2016 - Elsevier BV | Journal of Asia-Pacific Entomology

Artigo Acesso aberto Revisado por pares

Maribel Forero‐Castro, Cristina Robledo, Rocí­o Benito, María Abáigar, Ana A. Martín, Maryam Arefi, José Luís Fuster, Natalia de las Heras, N. Rodríguez, Jonathan Quintero, Susana Riesco, Lourdes Hermosín, Ignacio de la Fuente, Isabel Recio, Jordi Ribera, Jorge Labrador, José M. Alonso, C Olivier, Magdalena Sierra, Marta Megido, Luís A. Corchete, Juana Ciudad Pizarro, Juan Luis Garcı́a, Josep‐María Ribera, Jesús María Hernández‐Rivas,

Identifying additional genetic alterations associated with poor prognosis in acute lymphoblastic leukemia (ALL) is still a challenge. Aims: To characterize the presence of additional DNA copy number alterations (CNAs) in children and adults with ALL by whole-genome oligonucleotide array (aCGH) analysis, and to identify their associations with clinical features and outcome. Array-CGH was carried out in 265 newly diagnosed ALLs (142 children and 123 adults). The NimbleGen CGH 12x135K array (Roche) was ...

Tópico(s): Prenatal Screening and Diagnostics

2016 - Public Library of Science | PLoS ONE

Artigo Acesso aberto Revisado por pares

Laura Megido, L. Negral, L. Castrillón, Y. Fernández-Nava, Beatriz Suárez-Peña, Emilio Marañón,

PM10 from a suburban site in the northwest of Spain was assessed using data from chemical determinations, meteorological parameters, aerosol maps and five-day back trajectories of air masses. Temporal variations in the chemical composition of PM10 were subsequently related to stationary/mobile local sources and long-range transport stemming from Europe and North Africa. The presence of secondary inorganic species (sulphates, nitrates and ammonium) in airborne particulate matter constituted one of ...

Tópico(s): Air Quality Monitoring and Forecasting

2016 - Elsevier BV | Journal of Environmental Management

Artigo Acesso aberto Revisado por pares

Beatriz Suárez-Peña, L. Negral, L. Castrillón, Laura Megido, Elena Marañón, Y. Fernández-Nava,

This paper presents a study of the quartz fibrous filters used as a substrate for capturing the particulate matter (PM) present in the air. Although these substrates are widely used in environmental applications, their microstructure has been barely studied. The behavior of these devices during the filtration process was investigated in terms of their microstructure and the quartz fibers. Surface and cross sections were monitored. Scanning electronic microscopy with energy dispersive X-ray spectroscopy ( ...

Tópico(s): Surface Modification and Superhydrophobicity

2016 - Multidisciplinary Digital Publishing Institute | Materials

Artigo Revisado por pares

P. Ormaechea, L. Castrillón, E. Marañón, Y. Fernández-Nava, L. Negral, Laura Megido,

To increase the production of methane, when cattle manure (CM) is digested, pretreatments can be applied and/or the manure can be co-digested with other wastes. In this research work, a mixture of CM, food waste (FW) and raw glycerine (Gly) in a proportion in weight of 87% CM, 10% FW and 3% Gly was digested, (a) without pretreatment and (b) with pretreatment by ultrasound, applying a sonication energy of 1040 kJ/kg total solids. Specific methane production was 290 L CH4/kg volatile solids (VS) without ...

Tópico(s): Water-Energy-Food Nexus Studies

2016 - Taylor & Francis | Environmental Technology

Artigo Revisado por pares

Laura Megido, L. Negral, L. Castrillón, Beatriz Suárez-Peña, Y. Fernández-Nava, Elena Marañón,

Tópico(s): Vehicle emissions and performance

2016 - Springer Science+Business Media | Environmental Science and Pollution Research