Mairi Nicholson, Jonathan Northcroft, Waldemar Januszczak, John Dugdale, Tom Daveson, Barbara Hall, Tony Barrell, N J, Helen Kirwan-Taylor, Jon Swain, Tessa Mayes, Helen Davies, Rob Hughes, John Peter, V S, Dan Pearson, Emma Moore, Amanda Ursell, Miranda Nugent, Jonathan Miller, Juliet Fleming, Andrew Morgan, Jane Mulkerrins, J D, Nick Rufford, Gareth Walsh, Frank Whitford, Sheridan Morley, Ivo Tennant, Phil Cralgie, Matt Wolf, Kathryn Cooper, David Smith, Kirstie Hamilton City Editor, Alastair McCall, Edin Hamzic, Tim Richards, Rory Godson, David Cracknell Political Editor, Amber Cowman, Dominic Utton, Neil Wormald, Richard Green, E P, Andrew Sullivan, Clive Davis, Michael Coffey Principal, Kate Row, Guy Dennis, Lynne Truss, David Gordon, Mj, Tony Allen-Mills, Simon Wilde, Martin James, Anthony Sattin, Liz Kendall, Robert Winnett, Irwin Stelzer, Matt Rudd, Dido, Peter Wilson, Rosie Millard, Lawrence Dallaglio, Simon Grant, David Dougill, Nicholas Hellen Social Affairs Editor, Phil Baty, Angus Lamond, Robert Turnbull, Martin Searle, John Davis, Geraldine Hackett, Elizabeth Diss, David Hewson, Cally Law, Jonathon Carr-Brown, Alasdair Reid, Gary Loach, Hugh Canning, John Sutherland, Jeremy Clarkson, Graham Duffill, Edward Porter, Stewart Lee, Victoria Segal, Brain Glanville, Louise Taylor, Brian Pope Civil Engineers, Helen Kenny, Jane Renton, Cheryl Markosky, John O'Donnell, Nick Newman's, Liz Jones, Liz Edwards, William Morecambe, George Perry, Lydia Slater, David Eimer, Danny Scott, Adam Nathan, Nick Gardner, Terry O'Neill, Norman Smith, Beverley D'Silva, Richard Johnson, Philip Kinglsey, Christopher Silvester, Stuart Wavell, Roger Eglin, Peter J Wood, Paul Donovan, Alastair Hendy, Paul Taylor, Steve Boyd, Simon Mills, Brendan Kerrigan, Stan Labovitch, Barry Hughes, Lucinda Kemeny, Jasper Gerard, Paul Driver, Dan Cairms, Lucy Moore, John Humphrys, Ann McFerran, Maria McerLane, Emma McLaughlin, Dr John Marks, Richard Brooks, Ian Hawkey, Shelley Von Strunckel, Alex Clark, Christopher Morgan, David Leppard, Caroline Scott, Paul Durman, Tim Rayment, Dr Eric Jones, Alicia Wyllie, Jason Ball, Mark Edwards, Kirstie Hamilton, Steve Black, Susan Clark, David Lawrenson, R Letourneux, James Gilbert, Amir Shivji, Charty Durrant, Heather Litwin, Phil Baker, Christina Patterson, Hugo Barnacle, Francis Bennion, Bill Dawson, Victoria O'Brien, Sean Newsom, Amanda Harvey, Jean Weatherhead, Raymond Keene, Richard Dowden, David Cracknell, Cosmo Landesman, Zoe Brennan, Robbie Hudson, Rupret Steiner, Diana Wright, Stephen Jones, Dominic O'Connell, Barry Flatman, Nick Cain, Peta Bee, Erica Jong, C D Whelan, Andrew Smith, Natalie Graham, Michael Arditti, William Poel, Lois Rogers Medical correspondent, Luci Hoe, Nick Rennison, Keith Wheatley, Ghulam Hasnain, David Walsh, Bryan Appleyard, Gill Taylor, Stephen Armstrong, John Elliott, Ron Clarke, Christopher Mackenzie Chief Executive Officer and Deputy Chairman, Christopher Goodwin, Nicola Kraus, Janice Slivert, C A Guest, John Dehnel, Rory Godson Business Editor, John Duran, Maurice Chittenden, Dr David Stevenson, Richard Rae, Ray Hutton, Frank Fitzgibbon, Martin Ivens, Jonathan Leake, Caroline Brien, Darren Linthwaite, Joe LoveJoy, M E, Michael Sheridan, John Crossland, David Beard, John Harlow, Godfrey Smith, Maggi Bevan, Jane Owen, Dipesh Gadher, Matt Jansen, John Waples, A A Gill, Allan R Woods, Philip Haralambos, Matthew Campbell, Damaris Graham's, John Carey, Martin Vanner, Tom Robbins, Mary Braid, David Sinclair, Stephen Pettitt, Jonathan Calvert, Jonathan Leake Science Editor, Rw Johnson, Jason Corcoran, John Ford, Sally Kinnes, Naomi Caine, Nigel Powell, David Wickers, Jeremy Lyell, Alan Wilkinson, Joe Cawley, Roger Dobson, R B J T Allenby, Minette Marrin, Barrie McKay, Mark Hodson, Graham Norwood, Anthony Bourdain, Ian Clements, Joe Lovejoy, Jonathan Futrell, Rupert Steiner, Ted Childs, David Budworth, Hugh Pearman, Dan Cairns, Pete Oliver, T R Speight, Steve Henley, Tony Perrottet, Debbie Beckerman, Huw Beynon, John Alzlewood, Jim Kelly, Penny Perrick, Mrs Mills, Simon Crerar, Chris Feetenby, Joanna Simon, Matthew Goodman, G Simms, India Knight, Steve Grant, T R, Simon Howard, Danny Danziger, Louisa Harris, Barry Newcombe, Rosie Waterhouse, David Thomson, Richard Lewis, Boris Schapiro, Karen Robinson,
... tunnel Picture Gallery Amdega Quinta de Sao Roque Meia Praia Lagos Conquest fitted furniture Mind Body & Spirit ...
2002 - Gale Group | Sunday Times HA GDA
Antonio Freire, Jesús Hermida, J. Carlos Tutor,
... using the ACMIA and Abbott microparticle enzyme immunoassay (MEIA), which is the most widely used method for ... n=167) transplant recipients using the ACMIA and MEIA immunoassays. The MEIA results were corrected for hematocrit values lesser than ... were acceptable. In the comparison between ACMIA and MEIA results in the blood samples studied, the regression ... well-established interference of the hematocrit on the MEIA results, a highly significant negative correlation between the MEIA/ACMIA ratio and the hematocrit values was obtained ( ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2008 - Taylor & Francis | Upsala Journal of Medical Sciences
... avaliação e é baseado nas informações fornecidas por meia Plataforma Sucupira. Como resultado, disponibiliza uma lista com ...
CAPES
Amit Ghoshal, Steven J. Soldin,
... compare tacrolimus concentrations in blood samples using the MEIA II and MS methods at the lower and higher ends of the clinically relevant range. Methods: MEIA II was compared to our tandem MS/MS ... analysis. Data from recently published CAP surveys comparing MEIA II with MS procedures are also analyzed. Results: Comparison of MEIA II with our tandem MS/MS procedure by ... 9.0 ng/mL respectively, as determined by MEIA II. Below 9 ng/mL between day imprecision ... tacrolimus controls gave CVs of 12.16 for MEIA II and 7.82 for tandem MS/MS. ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2002 - Elsevier BV | Clinical Biochemistry
Amitava Dasgupta, Alice Wells, David A. Biddle,
... I in serum. The microparticle enzyme immunoassay (MEIA) for troponin I (Abbott Laboratories, Abbott ... the effect of bilirubin and hemolysis on the MEIA for troponin I and compared our assay with ... also measured CK‐MB concentration using the MEIA CK‐MB assay. One serum pool was ... troponin I concentrations were measured again using the MEIA and CLIA. We observed a statistically significant decrease ... concentration in the presence of bilirubin with the MEIA. For example, in serum pool 1, the troponin ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2001 - Wiley | Journal of Clinical Laboratory Analysis
Qin Yu, Hai Yang, Youmei Feng, Xiangliang Yang, Yanhong Zhu,
... aims to develop magnetic affinity enzyme-linked immunoassay (MEIA) for serological diagnosis of schistosomiasis based on recombinant ... for 6 weeks, the antibody was detected by MEIA. All of the infected mouse sera were effectively determined by MEIA. Compared with the enzyme-linked immunosorbent assay (ELISA), MEIA has a higher ratio of the mean positive ... same dilution ratio (3.92 versus 2.66). MEIA was further applied for diagnosis of human schistosomiasis. ... to assess the assay. The results showed that MEIA and ELISA had similarity in positive detection rates. ...
Tópico(s): Parasitic infections in humans and animals
2012 - Elsevier BV | Acta Tropica
... is replacing the popular microparticle enzyme-linked immunoassay (MEIA) as a cost-effective alternative technology. As more ... accuracy, precision, selectivity, and sensitivity of the tacrolimus MEIA are being challenged, using data from large populations ... patients over a 3-month period, by controlled MEIA and LC-MS procedures. Corresponding hematocrit and serum ... shown to be much better controlled than the MEIA during the 3-month parallel comparison study period. ... between the difference in tacrolimus concentrations determined by MEIA and LC-MS and hematocrit (and sometimes albumin). ...
Tópico(s): Organ Transplantation Techniques and Outcomes
2006 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring
K Jones, S Saadat-Lajevardi, Terry Lee, Ruth Horwatt, David Hicks, A. E. Johnston, David W. Holt,
... performance characteristics of a new microparticle enzyme immunoassay (MEIA) for the determination of sirolimus in whole blood. ... recently, this investigational immunoassay kit based on the MEIA technique.Calibration was made over the linear range ... were analyzed for sirolimus. A comparison of the MEIA and a validated HPLC/MS/MS assay analyzed ... extensive comparison of patient samples measured by the MEIA assay, a validated HPLC assay with UV detection ( ... calibrator. The results of the comparison between the MEIA and the HPLC/MS/MS assay showed mean ...
Tópico(s): Adenosine and Purinergic Signaling
2000 - Elsevier BV | Clinical Therapeutics
Ole Mogensen, Brynjólfur Mogensen,
... in serum were investigated. The microparticle enzyme immunoassay (MEIA) had a high degree of practicability and a ... samples from 72 ovarian cancer patients by the MEIA and a well documented manual enzyme immunoassay (Abbott ... 125 EIA). The correlation between the CA 125 MEIA and EIA results was non-linear. CA 125 ... l-1 (95% CI: 36-42) gave higher MEIA results and EIA values above this level resulted in lower MEIA values. The marker was measured before second-look ... off levels, the clinical information of CA 125 MEIA measurements was equivalent to that obtained by EIA. ...
Tópico(s): Ovarian cancer diagnosis and treatment
1992 - Taylor & Francis | Scandinavian Journal of Clinical and Laboratory Investigation
Paul Salm, Paul J. Taylor, A. K. Clark, Glenda A. Balderson, Anthony Grygotis, Ross Norris, Stephen V. Lynch, Leslie M. Shaw, Susan M. Pond,
... linked immunosorbent assay (ELISA), a microparticle enzyme immunoassay (MEIA I), and a high-performance liquid chromatography-tandem ... and 50.0 µg/l or for the MEIA I at all concentrations tested. Imprecision was acceptable ... and 50.0 µg/l, and for the MEIA I at 15.0 and 50.0 µg/ ... and 4.0 µg/l or for the MEIA I at 1.0 and 4.0 µg/ ... tacrolimus concentrations measured by HPLC-MS2, ELISA, and MEIA I was 1.9 to 31.8, 2. ... but unacceptable variability in values (SD > 13%). The MEIA I had unacceptable bias (1.7-1.8 ... These data indicated that neither the ELISA nor MEIA I is interchangeable with HPLC-MS2. Moreover, in ...
Tópico(s): Neurological Complications and Syndromes
1997 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring
Qin Yu, Hongkuan Yang, Fei Guan, Yi Feng, Xiangliang Yang, Yanhong Zhu,
... this study, a magnetic affinity enzyme-linked immunoassay (MEIA) based on the signal transduction protein 14-3- ... BALB/c mice were collected and analyzed with MEIA and ELISA. Both MEIA and ELISA based on Sj14-3-3 were ... used to analysis cross-reactions.Compared with ELISA, MEIA has a higher ratio of the mean positive ... were observed in humans, higher P/N of MEIA compared to ELISA (3.57 vs 2.68). ... the sera of paragonimiasis patients detected by both MEIA and ELISA.Our studies suggested that MEIA based on recombinant Sj14-3-3 protein (rSj14- ...
Tópico(s): Parasitic Infections and Diagnostics
2013 - Oxford University Press | Transactions of the Royal Society of Tropical Medicine and Hygiene
Kosuke Doki, Masato Homma, Tetsuo Hori, Takashi Tomita, Yuichi Hasegawa, Satoshi Ito, Kiyoshi Fukunaga, Michio Kaneko, Shigeru Chiba, Takayuki Sumida, Nobuhiro Ohkohchi, Yukinao Kohda,
... column-mediated immunoassay (ACMIA) and microparticle enzyme immunoassay (MEIA). Methods Blood concentrations of tacrolimus in 235 whole- ... Ht values did not differ between ACMIA and MEIA (median, range; 6.6, 0–29.1 vs ... 27.4 ng/ml). On the other hand, MEIA determined significantly higher tacrolimus concentrations in samples with ... difference was caused by overestimated blood concentrations in MEIA derived from lower Ht values, which could be ... using the Ht value for each sample (calculated MEIA (MEIAcalc)). The corrected concentrations (MEIAcalc; 10.8, 0– ...
Tópico(s): HIV Research and Treatment
2010 - Oxford University Press | Journal of Pharmacy and Pharmacology
Raymond G. Morris, Paul Salm, Paul J. Taylor, Fiona A. Wicks, Anastasia Theodossi,
... The recent reintroduction of the microparticle enzyme immunoassay (MEIA®) for sirolimus on the IMx® analyser has the ... This study, using patient samples, has compared the MEIA® sirolimus method with an established HPLC–tandem mass ... control materials (5, 11, 22 μg/L), the MEIA® showed acceptable validation criteria based on intra- and ... n=116). The resultant Deming regression line was: MEIA=1.3×HPLC-MS/MS+1.3 (r= ... but the sirolimus-metabolite cross-reactivity with the MEIA® antibody could be a substantive contributing factor. Whereas ...
Tópico(s): Pancreatic function and diabetes
2006 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring
Lorena Bouzas, J. Carlos Tutor,
... and the Abbott IMx sirolimus microparticle enzyme immunoassay (MEIA).The MEIA gave a concentration-dependent cross-reactivity with the ... and between-run coefficients of variation using the MEIA were <or=7.3%. In analyzing the different ... samples from patients and control materials using the MEIA and FPIA, a linear regression was found: MEIA=0.99FPIA-0.46 (ma68=0.32 microg/ ... r=0.967, p<0.001). Correcting the MEIA results by means of the linear regression equation ... analogous for both immunoassays.The Abbott IMx sirolimus MEIA permits the simple and precise determination of everolimus ...
Tópico(s): Pancreatic function and diabetes
2006 - Elsevier BV | Clinical Biochemistry
Yolanda Armend riz, Sarela Garc a, Rosa María López, Leonor Pou,
The comparison between the MEIA II and the EMIT assays for tacrolimus measurement and the interference by the hematocrit were evaluated in 93 samples from ... observed between the mean ± SD values obtained by MEIA II (5.14 ± 2.28 μg/L) and ... and EMIT = 1.088 (0.90, 1.35) MEIA II −0.38 (−1.65, −0.46), respectively. ... the hematocrit, the median differences between the methods (MEIA II minus EMIT) were as follows: hematocrit ≤25%, ... observed in 63.04% of samples analyzed by MEIA II and in 2.17% of samples analyzed ... the differences in the tacrolimus results obtained by MEIA and EMIT assays were higher in samples from ...
Tópico(s): Pharmacological Effects and Toxicity Studies
2005 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring
Simona Storti, Concetta Prontera, Michele Emdin, Claudio Passino, Paola Prati, G. Fontani, Isabella Giannelli, Luc Zyw, Simona Vittorini, Giancarlo Zucchelli, Aldo Clerico,
... natriuretic peptide (BNP), based on microparticle enzyme immunoassay (MEIA, AxSYM System, Abbott Laboratories), whose analytical characteristics and ... The within-run and total imprecision of the MEIA system were 18.4% and 19.8% at ... ng/l, respectively. The detection limit of the MEIA system was tested by repeatedly measuring (n = 20) ... ng/l) was obtained. A close linear relationship (MEIA = –22.5 + 1.71 POCT method, R = 0. ... 43.5 ± 14.0 years) was higher with MEIA than POCT, (25.9 ± 32.7 ng/l ... l, p < 0.0001). Our data suggest that MEIA and POCT have quite similar analytical performance but ...
Tópico(s): Cystic Fibrosis Research Advances
2004 - De Gruyter | Clinical Chemistry and Laboratory Medicine (CCLM)
Alistair D. Kippen, Fabrice Cerini, L. Vadas, Reto Stöcklin, Lan Phuong Vu, Robin E. Offord, Keith Rose,
... Although modern forms of radioimmunoassay, microparticle enzyme immunoassay (MEIA), 1The abbreviations used are: MEIA, microparticle enzyme immunoassay; CEI, chemiluminescent enzyme immunoassay; [2H14] ... two-site immunoradiometric assay. 1The abbreviations used are: MEIA, microparticle enzyme immunoassay; CEI, chemiluminescent enzyme immunoassay; [2H14] ... automated immunoassay. Insulin concentration was determined with a MEIA, IMx (Abbott Laboratories, Toyko, Japan), which uses mouse ... depending on the insulin concentration as determined by MEIA. Similarly, the amount of [2H14]C-peptide (the ...
Tópico(s): Metabolism, Diabetes, and Cancer
1997 - Elsevier BV | Journal of Biological Chemistry
Erin E. Barker, Arun Saini, Avihu Z. Gazit, Susan M. Shea, Sirine Baltagi, Brian F. Gage, Philip C. Spinella,
... mapping (TEG-PM) and multiple electrode impedance aggregometry (MEIA) as functional measures of platelet function would predict ... ADP) receptors would correlate between TEG-PM and MEIA results. Methods: In this prospective study from August ... Mortality Category predicted platelet transfusion. TEG-PM and MEIA results correlated for the AA receptor at all ... relevant information regarding platelet function compared to the MEIA at the ADP receptor in children requiring cardiopulmonary ... There was limited correlation between TEG-PM and MEIA results which raises a concern about the accuracy ...
Tópico(s): Cardiac and Coronary Surgery Techniques
2019 - Frontiers Media | Frontiers in Pediatrics
Produção Nacional
Afonso Pereira Fialho, Leandro Gonçalves Oliveira, Francisco Leonardo Tejerina‐Garro, Luiz Carlos Gomes,
This study was conducted in the Meia Ponte River basin, which is located in the Cerrado biome. The objective was to describe the structure of fish assemblages and to ... 35 municipalities of Goiás State. Springs of the Meia Ponte are located in the district of Itauçu ( ... tributaries and one in the channel of the Meia Ponte River, in its upper course, were selected ... the sampling station from the mouth of the Meia Ponte River (position; upper, intermediate and lower) were ... significant differences in fish assemblage structure in the Meia Ponte River basin for the seasons (rainy and ...
Tópico(s): Fish Ecology and Management Studies
2007 - Sociedade Brasileira de Ictiologia | Neotropical Ichthyology
Young Joo, Joo Suk Yang, Seok Lae Chae,
... by comparing them with a microparticle enzyme immunoassay (MEIA).HBsAg and anti-HBs were tested by the ... Results by ICA agreed completely with those of MEIA in all the 20 HBsAg-negative sera and ... sample. Among the 20 HBsAg-positive sera by MEIA, 17 were positive by ICA using Green Cross ... Among the 20 anti-HBs-positive sera by MEIA, 19 were positive by ICA using Green Cross ... indigenously produced ICA kits are as sensitive as MEIA for the detection of anti-HBs, but are less sensitive than MEIA for HBsAg. The ICA kits for the rapid ...
Tópico(s): Viral gastroenteritis research and epidemiology
2006 - Seoul National University | Annals of Laboratory Medicine
S. Halide Akbaş, Sebahat Özdem, Serkan Çağlar, Murat Tuncer, Alihan Gürkan, L. Yücetin, Yeşim Şenol, A. Demirbaş, Meral Gültekin, F Ersoy, M Akaydın,
... different analytical methods, namely the microparticle enzyme immunoassay (MEIA II) and enzyme multiplied immunoassay technique (EMIT). The ... 2430 measurements) measured with EMIT (n = 1171) and MEIA II (n = 1259) methods in whole blood samples ... compared. The whole blood tacrolimus concentrations measured with MEIA II method were affected much more significantly by ... parameters than those measured with EMIT method. In MEIA II method, RDW (r = 0.479, P < 0. ... concentration in patients with Htc values ≤25% in MEIA II method. The results of the present study ...
Tópico(s): Hemoglobinopathies and Related Disorders
2005 - Elsevier BV | Clinical Biochemistry
Takashi Tomita, Masato Homma, Kenji Yuzawa, Nobuhiro Ohkohchi, Tetsuo Hori, Michio Kaneko, Yuichi Hasegawa, Hiroshi Kojima, Toshiro Nagasawa, Yukinao Kohda,
... of hematocrit (Ht) value on microparticle enzyme immunoassay (MEIA) of tacrolimus concentration were examined in 1063 whole- ... liver, 20 kidney, and 9 bone marrow transplantations). MEIA guarantees the test's assay quality for blood ... were tested by 3 assay methods for tacrolimus: MEIA, modified, corrected MEIA (cMEIA), and enzyme-linked immunosorbent assay (ELISA). MEIA gave higher blood concentrations of tacrolimus than ELISA ( ... 001). This difference was generated by overestimation in MEIA and was not observed in samples with normal ...
Tópico(s): Hemoglobinopathies and Related Disorders
2005 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring
Jan L Cogill, Paul J. Taylor, Ian S Westley, Raymond G. Morris, Stephen V. Lynch, Anthony G. Johnson,
We evaluated the MEIA II with blood samples with added tacrolimus (3.0, 5.0, 11.0, and 22.0 microg/L). The ... and renal (n = 113) patient samples measured by MEIA II against HPLC-tandem mass spectrometry (HPLC-MS/ ... transplant patient samples, measured by HPLC-MS/MS, MEIA II will have the corresponding range estimates of ... observed between the two transplant groups studied. The MEIA II is an improvement on the previous MEIA I and is suitable for the therapeutic drug ...
Tópico(s): Pharmacological Effects and Toxicity Studies
1998 - American Association for Clinical Chemistry | Clinical Chemistry
Victor W. Armstrong, Ekkehard Schuetz, Qingling Zhang, Stephan Groothuisen, C. Scholz, Maria Shipkova, Hoda Aboleneen, Michael Oellerich,
... spectrometry (LC/MS/MS) and microparticle enzyme immunoassay (MEIA-II). Data were analyzed by difference plots and ... median (95% confidence intervals) of the method differences. MEIA-II results were on average 2.00 microg/ ... tested, 25 displayed differences >/=3 microg/L between MEIA-II and PFA: median difference, 4.65 microg/ ... 0.85 microg/L), and the difference between MEIA-II and LC/MS/MS was 3.67 ... differences were observed for the remaining 79 specimens: MEIA-II minus LC/MS/MS, 1.78 microg/ ...
Tópico(s): Pharmacological Effects and Toxicity Studies
1998 - American Association for Clinical Chemistry | Clinical Chemistry
Margot J. Wyrwoll, Eva S. van Walree, Geert Hamer, Nadja Rotte, M. Mahdi Motazacker, Hanne Meijers-Heijboer, Mariëlle Alders, Andreas Meißner, Elke Kaminsky, Marius Wöste, Claudia Krallmann, Sabine Kliesch, T. Hunt, Amander T. Clark, Sherman J. Silber, Birgit Stallmeyer, Corinna Friedrich, Ans M. M. van Pelt, Inge B. Mathijssen, Frank Tüttelmann,
... MERGE) study, including 90 males with meiotic arrest (MeiA). Independently, exome sequencing was performed in a man with MeiA from a large consanguineous family.Assuming an autosomal- ... infertility in 2 out of 90 men with MeiA and overall in 4 out of 902 azoospermic ... biallelic variants in MSH4 in two men with MeiA and in the sister of one proband with ... testicular biopsy. We also provide further evidence that MeiA in men and POI in women share the ...
Tópico(s): Genomics and Chromatin Dynamics
2021 - Oxford University Press | Human Reproduction
Sven Van Poucke, Kris Stevens, Rick J. H. Wetzels, Cécile Kicken, Paul Verhezen, Maurice Theunissen, Gerhardus J.A.J.M. Kuiper, René van Oerle, Yvonne Henskens, Marcus D. Lancé,
... PF was assessed by multiple electrode impedance aggregometry (MEIA) in whole blood and by light transmission aggregometry ( ... collagen, and thrombin-receptor-activating peptide. LTA and MEIA analysis demonstrated significant platelet dysfunction after CPB, with ... unchanged throughout the study. Correlation analyses revealed that MEIA and rotational thromboelastometry (ROTEM), but not LTA, were ... and hematocrit. No correlations were found between LTA, MEIA, ROTEM, PC, and clinical outcome parameters. Our results ...
Tópico(s): Antiplatelet Therapy and Cardiovascular Diseases
2016 - Informa | Platelets
David W. Holt, Didier A. Mandelbrot, Michael A. Tortorici, Joan Korth‐Bradley, Debra Sierka, David Lévy, Sandi See Tai, Gary L. Horowitz,
... time of the IM x microparticle enzyme immunoassay ( MEIA ), Architect chemiluminescent microparticle immunoassay ( CMIA ), and liquid chromatography ... samples were compared with LC / MS / MS , the MEIA assay showed an overall mean percent bias of − ... 2007 through 2009. The CMIA , which replaced the MEIA assay, had a mean percent bias of 21. ... 2007 through 2012. Similarly, for spiked samples, the MEIA showed an increasingly negative bias over time vs. ... CMIA values were more than 25% higher than MEIA values. These results highlight the importance of continued ...
Tópico(s): Pancreatic function and diabetes
2014 - Wiley | Clinical Transplantation
Shigeru Marubashi, Hiroaki Nagano, Shogo Kobayashi, Hidetoshi Eguchi, Yutaka Takeda, Masahiro Tanemura, Koji Umeshita, Morito Monden, Yuichiro� Doki, Masaki Mori,
... established Abbott IMx Tacrolimus II microparticle enzyme immunoassay (MEIA) in liver transplant recipients and evaluate its accuracy. ... trough level using 2 different methods, CMIA and MEIA. The posttransplant time, hematocrit, and other clinical parameters ... from 57 liver transplant recipients by CMIA and MEIA. The correlation in FK level between the 2 ... 941). However, the FK level was underestimated in MEIA by more than 23% in samples with an ... and 5 ng/mL. CMIA is superior to MEIA in measuring low FK level, allowing the FK ...
Tópico(s): Neurological Complications and Syndromes
2010 - Wiley | The Journal of Clinical Pharmacology
Tomoyuki Yamada, Kaoru Suzuki, Ken Iguchi, Yasutaka Kanada, Ryuji Kato, Yoshio Ijiri, Masami Nishihara, Sumiko Murakami, Tetsuya Hayashi, Hiroshi Tamai, Kazuhiko Tanaka,
... assays (fluorescence polarization immunoassay [FPIA], microparticle enzyme immunoassay [MEIA], and affinity column-mediated immunoassay [ACMIA]) to determine ... eplerenone and antidigoxin antibodies. Furthermore, we used FPIA, MEIA, and ACMIA to measure the apparent digoxin concentration ... crossreaction between eplerenone and digoxin was determined by MEIA. In the interference of eplerenone coadministered with digoxin, ... digoxin was increased in FPIA, but decreased in MEIA and ACMIA. The results suggest that eplerenone crossreacts ...
Tópico(s): Ion channel regulation and function
2010 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring