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... tunnel Picture Gallery Amdega Quinta de Sao Roque Meia Praia Lagos Conquest fitted furniture Mind Body & Spirit ...
2002 - Gale Group | Sunday Times HA GDA
Amit Ghoshal, Steven J. Soldin,
... compare tacrolimus concentrations in blood samples using the MEIA II and MS methods at the lower and higher ends of the clinically relevant range. Methods: MEIA II was compared to our tandem MS/MS ... analysis. Data from recently published CAP surveys comparing MEIA II with MS procedures are also analyzed. Results: Comparison of MEIA II with our tandem MS/MS procedure by ... 9.0 ng/mL respectively, as determined by MEIA II. Below 9 ng/mL between day imprecision ... tacrolimus controls gave CVs of 12.16 for MEIA II and 7.82 for tandem MS/MS. ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2002 - Elsevier BV | Clinical Biochemistry
... avaliação e é baseado nas informações fornecidas por meia Plataforma Sucupira. Como resultado, disponibiliza uma lista com ...
CAPES
Antonio Freire, Jesús Hermida, J. Carlos Tutor,
... using the ACMIA and Abbott microparticle enzyme immunoassay (MEIA), which is the most widely used method for ... n=167) transplant recipients using the ACMIA and MEIA immunoassays. The MEIA results were corrected for hematocrit values lesser than ... were acceptable. In the comparison between ACMIA and MEIA results in the blood samples studied, the regression ... well-established interference of the hematocrit on the MEIA results, a highly significant negative correlation between the MEIA/ACMIA ratio and the hematocrit values was obtained ( ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2008 - Taylor & Francis | Upsala Journal of Medical Sciences
Amitava Dasgupta, Alice Wells, David A. Biddle,
... I in serum. The microparticle enzyme immunoassay (MEIA) for troponin I (Abbott Laboratories, Abbott ... the effect of bilirubin and hemolysis on the MEIA for troponin I and compared our assay with ... also measured CK‐MB concentration using the MEIA CK‐MB assay. One serum pool was ... troponin I concentrations were measured again using the MEIA and CLIA. We observed a statistically significant decrease ... concentration in the presence of bilirubin with the MEIA. For example, in serum pool 1, the troponin ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2001 - Wiley | Journal of Clinical Laboratory Analysis
Ole Mogensen, Brynjólfur Mogensen,
... in serum were investigated. The microparticle enzyme immunoassay (MEIA) had a high degree of practicability and a ... samples from 72 ovarian cancer patients by the MEIA and a well documented manual enzyme immunoassay (Abbott ... 125 EIA). The correlation between the CA 125 MEIA and EIA results was non-linear. CA 125 ... l-1 (95% CI: 36-42) gave higher MEIA results and EIA values above this level resulted in lower MEIA values. The marker was measured before second-look ... off levels, the clinical information of CA 125 MEIA measurements was equivalent to that obtained by EIA. ...
Tópico(s): Ovarian cancer diagnosis and treatment
1992 - Taylor & Francis | Scandinavian Journal of Clinical and Laboratory Investigation
... is replacing the popular microparticle enzyme-linked immunoassay (MEIA) as a cost-effective alternative technology. As more ... accuracy, precision, selectivity, and sensitivity of the tacrolimus MEIA are being challenged, using data from large populations ... patients over a 3-month period, by controlled MEIA and LC-MS procedures. Corresponding hematocrit and serum ... shown to be much better controlled than the MEIA during the 3-month parallel comparison study period. ... between the difference in tacrolimus concentrations determined by MEIA and LC-MS and hematocrit (and sometimes albumin). ...
Tópico(s): Organ Transplantation Techniques and Outcomes
2006 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring
Qin Yu, Hai Yang, Youmei Feng, Xiangliang Yang, Yanhong Zhu,
... aims to develop magnetic affinity enzyme-linked immunoassay (MEIA) for serological diagnosis of schistosomiasis based on recombinant ... for 6 weeks, the antibody was detected by MEIA. All of the infected mouse sera were effectively determined by MEIA. Compared with the enzyme-linked immunosorbent assay (ELISA), MEIA has a higher ratio of the mean positive ... same dilution ratio (3.92 versus 2.66). MEIA was further applied for diagnosis of human schistosomiasis. ... to assess the assay. The results showed that MEIA and ELISA had similarity in positive detection rates. ...
Tópico(s): Parasitic infections in humans and animals
2012 - Elsevier BV | Acta Tropica
K Jones, S Saadat-Lajevardi, Terry Lee, Ruth Horwatt, David Hicks, A. E. Johnston, David W. Holt,
... performance characteristics of a new microparticle enzyme immunoassay (MEIA) for the determination of sirolimus in whole blood. ... recently, this investigational immunoassay kit based on the MEIA technique.Calibration was made over the linear range ... were analyzed for sirolimus. A comparison of the MEIA and a validated HPLC/MS/MS assay analyzed ... extensive comparison of patient samples measured by the MEIA assay, a validated HPLC assay with UV detection ( ... calibrator. The results of the comparison between the MEIA and the HPLC/MS/MS assay showed mean ...
Tópico(s): Adenosine and Purinergic Signaling
2000 - Elsevier BV | Clinical Therapeutics
Paul Salm, Paul J. Taylor, A. K. Clark, Glenda A. Balderson, Anthony Grygotis, Ross Norris, Stephen V. Lynch, Leslie M. Shaw, Susan M. Pond,
... linked immunosorbent assay (ELISA), a microparticle enzyme immunoassay (MEIA I), and a high-performance liquid chromatography-tandem ... and 50.0 µg/l or for the MEIA I at all concentrations tested. Imprecision was acceptable ... and 50.0 µg/l, and for the MEIA I at 15.0 and 50.0 µg/ ... and 4.0 µg/l or for the MEIA I at 1.0 and 4.0 µg/ ... tacrolimus concentrations measured by HPLC-MS2, ELISA, and MEIA I was 1.9 to 31.8, 2. ... but unacceptable variability in values (SD > 13%). The MEIA I had unacceptable bias (1.7-1.8 ... These data indicated that neither the ELISA nor MEIA I is interchangeable with HPLC-MS2. Moreover, in ...
Tópico(s): Neurological Complications and Syndromes
1997 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring
Kosuke Doki, Masato Homma, Tetsuo Hori, Takashi Tomita, Yuichi Hasegawa, Satoshi Ito, Kiyoshi Fukunaga, Michio Kaneko, Shigeru Chiba, Takayuki Sumida, Nobuhiro Ohkohchi, Yukinao Kohda,
... column-mediated immunoassay (ACMIA) and microparticle enzyme immunoassay (MEIA). Methods Blood concentrations of tacrolimus in 235 whole- ... Ht values did not differ between ACMIA and MEIA (median, range; 6.6, 0–29.1 vs ... 27.4 ng/ml). On the other hand, MEIA determined significantly higher tacrolimus concentrations in samples with ... difference was caused by overestimated blood concentrations in MEIA derived from lower Ht values, which could be ... using the Ht value for each sample (calculated MEIA (MEIAcalc)). The corrected concentrations (MEIAcalc; 10.8, 0– ...
Tópico(s): HIV Research and Treatment
2010 - Oxford University Press | Journal of Pharmacy and Pharmacology
Lorena Bouzas, J. Carlos Tutor,
... and the Abbott IMx sirolimus microparticle enzyme immunoassay (MEIA).The MEIA gave a concentration-dependent cross-reactivity with the ... and between-run coefficients of variation using the MEIA were <or=7.3%. In analyzing the different ... samples from patients and control materials using the MEIA and FPIA, a linear regression was found: MEIA=0.99FPIA-0.46 (ma68=0.32 microg/ ... r=0.967, p<0.001). Correcting the MEIA results by means of the linear regression equation ... analogous for both immunoassays.The Abbott IMx sirolimus MEIA permits the simple and precise determination of everolimus ...
Tópico(s): Pancreatic function and diabetes
2006 - Elsevier BV | Clinical Biochemistry
Raymond G. Morris, Paul Salm, Paul J. Taylor, Fiona A. Wicks, Anastasia Theodossi,
... The recent reintroduction of the microparticle enzyme immunoassay (MEIA®) for sirolimus on the IMx® analyser has the ... This study, using patient samples, has compared the MEIA® sirolimus method with an established HPLC–tandem mass ... control materials (5, 11, 22 μg/L), the MEIA® showed acceptable validation criteria based on intra- and ... n=116). The resultant Deming regression line was: MEIA=1.3×HPLC-MS/MS+1.3 (r= ... but the sirolimus-metabolite cross-reactivity with the MEIA® antibody could be a substantive contributing factor. Whereas ...
Tópico(s): Pancreatic function and diabetes
2006 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring
Yolanda Armend riz, Sarela Garc a, Rosa María López, Leonor Pou,
The comparison between the MEIA II and the EMIT assays for tacrolimus measurement and the interference by the hematocrit were evaluated in 93 samples from ... observed between the mean ± SD values obtained by MEIA II (5.14 ± 2.28 μg/L) and ... and EMIT = 1.088 (0.90, 1.35) MEIA II −0.38 (−1.65, −0.46), respectively. ... the hematocrit, the median differences between the methods (MEIA II minus EMIT) were as follows: hematocrit ≤25%, ... observed in 63.04% of samples analyzed by MEIA II and in 2.17% of samples analyzed ... the differences in the tacrolimus results obtained by MEIA and EMIT assays were higher in samples from ...
Tópico(s): Pharmacological Effects and Toxicity Studies
2005 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring
Simona Storti, Concetta Prontera, Michele Emdin, Claudio Passino, Paola Prati, G. Fontani, Isabella Giannelli, Luc Zyw, Simona Vittorini, Giancarlo Zucchelli, Aldo Clerico,
... natriuretic peptide (BNP), based on microparticle enzyme immunoassay (MEIA, AxSYM System, Abbott Laboratories), whose analytical characteristics and ... The within-run and total imprecision of the MEIA system were 18.4% and 19.8% at ... ng/l, respectively. The detection limit of the MEIA system was tested by repeatedly measuring (n = 20) ... ng/l) was obtained. A close linear relationship (MEIA = –22.5 + 1.71 POCT method, R = 0. ... 43.5 ± 14.0 years) was higher with MEIA than POCT, (25.9 ± 32.7 ng/l ... l, p < 0.0001). Our data suggest that MEIA and POCT have quite similar analytical performance but ...
Tópico(s): Cystic Fibrosis Research Advances
2004 - De Gruyter | Clinical Chemistry and Laboratory Medicine (CCLM)
Qin Yu, Hongkuan Yang, Fei Guan, Yi Feng, Xiangliang Yang, Yanhong Zhu,
... this study, a magnetic affinity enzyme-linked immunoassay (MEIA) based on the signal transduction protein 14-3- ... BALB/c mice were collected and analyzed with MEIA and ELISA. Both MEIA and ELISA based on Sj14-3-3 were ... used to analysis cross-reactions.Compared with ELISA, MEIA has a higher ratio of the mean positive ... were observed in humans, higher P/N of MEIA compared to ELISA (3.57 vs 2.68). ... the sera of paragonimiasis patients detected by both MEIA and ELISA.Our studies suggested that MEIA based on recombinant Sj14-3-3 protein (rSj14- ...
Tópico(s): Parasitic Infections and Diagnostics
2013 - Oxford University Press | Transactions of the Royal Society of Tropical Medicine and Hygiene
Alistair D. Kippen, Fabrice Cerini, L. Vadas, Reto Stöcklin, Lan Phuong Vu, Robin E. Offord, Keith Rose,
... Although modern forms of radioimmunoassay, microparticle enzyme immunoassay (MEIA), 1The abbreviations used are: MEIA, microparticle enzyme immunoassay; CEI, chemiluminescent enzyme immunoassay; [2H14] ... two-site immunoradiometric assay. 1The abbreviations used are: MEIA, microparticle enzyme immunoassay; CEI, chemiluminescent enzyme immunoassay; [2H14] ... automated immunoassay. Insulin concentration was determined with a MEIA, IMx (Abbott Laboratories, Toyko, Japan), which uses mouse ... depending on the insulin concentration as determined by MEIA. Similarly, the amount of [2H14]C-peptide (the ...
Tópico(s): Metabolism, Diabetes, and Cancer
1997 - Elsevier BV | Journal of Biological Chemistry
Produção Nacional
Afonso Pereira Fialho, Leandro Gonçalves Oliveira, Francisco Leonardo Tejerina‐Garro, Luiz Carlos Gomes,
This study was conducted in the Meia Ponte River basin, which is located in the Cerrado biome. The objective was to describe the structure of fish assemblages and to ... 35 municipalities of Goiás State. Springs of the Meia Ponte are located in the district of Itauçu ( ... tributaries and one in the channel of the Meia Ponte River, in its upper course, were selected ... the sampling station from the mouth of the Meia Ponte River (position; upper, intermediate and lower) were ... significant differences in fish assemblage structure in the Meia Ponte River basin for the seasons (rainy and ...
Tópico(s): Fish Ecology and Management Studies
2007 - Sociedade Brasileira de Ictiologia | Neotropical Ichthyology
Young Joo, Joo Suk Yang, Seok Lae Chae,
... by comparing them with a microparticle enzyme immunoassay (MEIA).HBsAg and anti-HBs were tested by the ... Results by ICA agreed completely with those of MEIA in all the 20 HBsAg-negative sera and ... sample. Among the 20 HBsAg-positive sera by MEIA, 17 were positive by ICA using Green Cross ... Among the 20 anti-HBs-positive sera by MEIA, 19 were positive by ICA using Green Cross ... indigenously produced ICA kits are as sensitive as MEIA for the detection of anti-HBs, but are less sensitive than MEIA for HBsAg. The ICA kits for the rapid ...
Tópico(s): Viral gastroenteritis research and epidemiology
2006 - Seoul National University | Annals of Laboratory Medicine
S. Halide Akbaş, Sebahat Özdem, Serkan Çağlar, Murat Tuncer, Alihan Gürkan, L. Yücetin, Yeşim Şenol, A. Demirbaş, Meral Gültekin, F Ersoy, M Akaydın,
... different analytical methods, namely the microparticle enzyme immunoassay (MEIA II) and enzyme multiplied immunoassay technique (EMIT). The ... 2430 measurements) measured with EMIT (n = 1171) and MEIA II (n = 1259) methods in whole blood samples ... compared. The whole blood tacrolimus concentrations measured with MEIA II method were affected much more significantly by ... parameters than those measured with EMIT method. In MEIA II method, RDW (r = 0.479, P < 0. ... concentration in patients with Htc values ≤25% in MEIA II method. The results of the present study ...
Tópico(s): Hemoglobinopathies and Related Disorders
2005 - Elsevier BV | Clinical Biochemistry
Takashi Tomita, Masato Homma, Kenji Yuzawa, Nobuhiro Ohkohchi, Tetsuo Hori, Michio Kaneko, Yuichi Hasegawa, Hiroshi Kojima, Toshiro Nagasawa, Yukinao Kohda,
... of hematocrit (Ht) value on microparticle enzyme immunoassay (MEIA) of tacrolimus concentration were examined in 1063 whole- ... liver, 20 kidney, and 9 bone marrow transplantations). MEIA guarantees the test's assay quality for blood ... were tested by 3 assay methods for tacrolimus: MEIA, modified, corrected MEIA (cMEIA), and enzyme-linked immunosorbent assay (ELISA). MEIA gave higher blood concentrations of tacrolimus than ELISA ( ... 001). This difference was generated by overestimation in MEIA and was not observed in samples with normal ...
Tópico(s): Hemoglobinopathies and Related Disorders
2005 - Lippincott Williams & Wilkins | Therapeutic Drug Monitoring
Victor W. Armstrong, Ekkehard Schuetz, Qingling Zhang, Stephan Groothuisen, C. Scholz, Maria Shipkova, Hoda Aboleneen, Michael Oellerich,
... spectrometry (LC/MS/MS) and microparticle enzyme immunoassay (MEIA-II). Data were analyzed by difference plots and ... median (95% confidence intervals) of the method differences. MEIA-II results were on average 2.00 microg/ ... tested, 25 displayed differences >/=3 microg/L between MEIA-II and PFA: median difference, 4.65 microg/ ... 0.85 microg/L), and the difference between MEIA-II and LC/MS/MS was 3.67 ... differences were observed for the remaining 79 specimens: MEIA-II minus LC/MS/MS, 1.78 microg/ ...
Tópico(s): Pharmacological Effects and Toxicity Studies
1998 - American Association for Clinical Chemistry | Clinical Chemistry
Jan L Cogill, Paul J. Taylor, Ian S Westley, Raymond G. Morris, Stephen V. Lynch, Anthony G. Johnson,
We evaluated the MEIA II with blood samples with added tacrolimus (3.0, 5.0, 11.0, and 22.0 microg/L). The ... and renal (n = 113) patient samples measured by MEIA II against HPLC-tandem mass spectrometry (HPLC-MS/ ... transplant patient samples, measured by HPLC-MS/MS, MEIA II will have the corresponding range estimates of ... observed between the two transplant groups studied. The MEIA II is an improvement on the previous MEIA I and is suitable for the therapeutic drug ...
Tópico(s): Pharmacological Effects and Toxicity Studies
1998 - American Association for Clinical Chemistry | Clinical Chemistry
Erin E. Barker, Arun Saini, Avihu Z. Gazit, Susan M. Shea, Sirine Baltagi, Brian F. Gage, Philip C. Spinella,
... mapping (TEG-PM) and multiple electrode impedance aggregometry (MEIA) as functional measures of platelet function would predict ... ADP) receptors would correlate between TEG-PM and MEIA results. Methods: In this prospective study from August ... Mortality Category predicted platelet transfusion. TEG-PM and MEIA results correlated for the AA receptor at all ... relevant information regarding platelet function compared to the MEIA at the ADP receptor in children requiring cardiopulmonary ... There was limited correlation between TEG-PM and MEIA results which raises a concern about the accuracy ...
Tópico(s): Cardiac and Coronary Surgery Techniques
2019 - Frontiers Media | Frontiers in Pediatrics
A. Hedin, Lena Carlsson, Alix K. Berglund, Sten Hammarström,
A two-site monoclonal antibody-enzyme immunoassay (MEIA) for carcinoembryonic antigen (CEA) was developed that uses two monoclonal anti-CEA antibodies, which recognize two different epitopes in the peptide moiety of ... normal tissue extracts did not react in the MEIA even when tested at very high concentrations. Sera ... were analyzed for CEA levels by using the MEIA and in parallel a conventional radioimmunoassay. A significant ... in specificity for carcinomas was obtained with the MEIA. This was essentially due to a decrease of ...
Tópico(s): Peptidase Inhibition and Analysis
1983 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Lorena Bouzas, Jesús Hermida, J. Carlos Tutor,
... for blood sirolimus determination, the microparticle enzyme immunoassay (MEIA) run on the IMx® analyser is widely used ... run on a TDx® analyser (Abbott Laboratories), Sirolimus MEIA run on an IMx® analyser (Abbott Laboratories), and ... HPLC + 0.43 (n=104, r=0.874), MEIA = 1.14 HPLC (n=146, r=0.892), and FPIA = 1.00 MEIA + 0.29 (n=106, r=0.941). Better ... valid alternative with an analogous performance to the MEIA for the therapeutic monitoring of sirolimus.
Tópico(s): Electrolyte and hormonal disorders
2009 - Taylor & Francis | Upsala Journal of Medical Sciences
J. W. Safford, Glenda G. Abbott, MaryCaren Craine, R. Glen Macdonald,
Fully automated microparticle enzyme immunoassays (MEIA) for the IMx immunoassay analyser were developed to detect IgG and IgM antibodies to Toxoplasma gondii. The IgG MEIA results are expressed in International Units (IU) of ... for at least one month. The qualitative IgM MEIA expresses results as an index using a single calibrator included in each run. The Toxo IgG MEIA and Toxo IgM MEIA were in 98% and 97% agreement, respectively, with ...
Tópico(s): T-cell and Retrovirus Studies
1991 - BMJ | Journal of Clinical Pathology
Masato Homma, Takashi Tomita, Kenji Yuzawa, Yasutsugu Takada, Yukinao Kohda,
... tacrolimus between the assay methods, microparticle enzyme immunoassay (MEIA) and enzyme linked immunosorbent assay (ELISA) was observed in a liver transplant recipient with anemia. MEIA provided significantly higher concentration than those of ELISA ( ... 1—3.3 ng/ml was observed in MEIA applying to the blood samples obtained from the ... in the samples with lower hematocrit, suggesting that MEIA gave incorrect blood tacrolimus during anemia. Since MEIA potentially overestimates the tacrolimus levels, ELISA should be ...
Tópico(s): Transplantation: Methods and Outcomes
2002 - Pharmaceutical Society of Japan | Biological and Pharmaceutical Bulletin
Man Ki Ju, Hojin Chang, H. J. Kim, Kyu Ha Huh, Hyung Joon Ahn, Myoung Soo Kim, Soon Il Kim, Yu Seun Kim,
... column–mediated immunoassay (ACMIA) and microparticle enzyme immunoassay (MEIA), comparing differences in the tacrolimus concentrations measured by ... ACMIA method and IMx tacrolimus II for the MEIA method. Tacrolimus concentrations measured by the ACMIA method ( ... 154) closely correlated with those measured by the MEIA method (r = 0.84). The Bland-Altman plot ... trends. The tacrolimus levels determined by both the MEIA method and the ACMIA method were not influenced ... but the difference between the 2 methods (ACMIA − MEIA) tended to be larger in low hematocrit samples ( ...
Tópico(s): HIV/AIDS drug development and treatment
2008 - Elsevier BV | Transplantation Proceedings