Béatrice Mandon‐Pepin, Céline Derbois, Fumihiko Matsuda, Corinne Cotinot, Debra J. Wolgemuth, Kathleen N. Smith, Ken McElreavey, Alain Nicolas, Marc Fellous,
... systématique d'éventuelles mutations dans des gènes de méiose, gènes hautement conservés au cours de l'évolution ... a jamais été entreprise. Le déroulement de la méiose et des gènes associés ont été largement caractérisés ... montrant leurs rôles essentiels au cours de la méiose et dans la gamétogénèse. De plus, les phénotypes ... identifier d'éventuelles mutations dans 5 gènes de méiose (DMC1, SPO11, MSH4, MSH5, CCNA1) sur 145 patients ... respectivement. Les conséquences de telles mutations sur la méiose sont actuellement à l'étude chez la levure. ...
Tópico(s): Reproductive Biology and Fertility
2002 - Elsevier BV | Gynécologie Obstétrique & Fertilité
Antonella Carsana, Giulia Frisso, Maria Roberta Tremolaterra, Elisabetta Ricci, Domenico De Rasmo, Francesco Salvatore,
... mapped 25 intragenic recombinations out of 273 informative meioses analyzed. The terminal regions of a gene are ... mapped 25 intragenic recombinations out of 273 informative meioses analyzed. The terminal regions of a gene are ... intragenic recombinations (Figure 2B) out of 273 informative meioses analyzed. Thus, the recombination frequency was about 9%. ... recombination events found in our population, the informative meioses analyzed for each STR pair and the distances ... this region could contain a mutation.Table 2Informative Meioses and Recombination Events between the Intragenic STRs in ...
Tópico(s): RNA modifications and cancer
2007 - Elsevier BV | Journal of Molecular Diagnostics
Hongyu Zhao, Jinming Li, Wendy P. Robinson,
... the probability distribution of the recombination events underlying meioses leading to UPD. We can also use this ... UPD data and to inspect recombination differences between meioses exhibiting UPD and normal meioses. The proposed method has been implemented in a ... the probability distribution of the recombination events underlying meioses leading to UPD. We can also use this ... UPD data and to inspect recombination differences between meioses exhibiting UPD and normal meioses. The proposed method has been implemented in a ...
Tópico(s): Genomic variations and chromosomal abnormalities
2000 - Elsevier BV | The American Journal of Human Genetics
P. MAULÉON, Françoise Berthelot, J. Bézard,
... gonade d'embryon de brebis qui commencent leur méïose au début, au milieu, ou à la fin ... forte- ment des ovocytes qui débutaient alors leur méïose.La proportion variable d'ovocytes provenant de chacun ... de brebis) après laquelle le déroulement de la méïose in vitro se fait normalement mais avant la- ... reprendre l'enchaînement des processus qui induisent la méïose (greffes d'ovaires cultivés 10 jours chez des ... ou général favorables à l'induction de la méïose et d'échanges entre cellules germinales et cellules ...
Tópico(s): Agriculture and Rural Development Research
1975 - Elsevier BV | annales de biologie animale biochimie biophysique
Produção Nacional
Revisado por pares
María Teresa Schifino-Wittmann, Miguel Dall’Agnol,
... formados por uma não redução cromossômica durante a meiose, que pode ocorrer de duas formas: na meiose I, pela RPD (restituição na primeira divisão), ou na meiose II, pela RSD (restituição na segunda divisão). Normalmente, ... A detecção dos gametas 2n, mais estudados na meiose masculina do que na feminina, é mais freqüentemente ... presença de díades e tríades ao final da meiose II. No melhoramento, são utilizados basicamente de duas ...
Tópico(s): Plant Genetic and Mutation Studies
2001 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural
John Michael O. Rañola, Quanhui Liu, Elisabeth A. Rosenthal, Brian H. Shirts,
... likelihood ratios (CSLR), and a simpler method, counting meioses. Both FLB and CSLR outperform counting meioses when dealing with pathogenic variants, though counting meioses is not far behind. For benign variants, FLB and CSLR greatly outperform as counting meioses is unable to generate evidence for benign variants. ... org ) which implements the CSLR, FLB, and Counting Meioses methods for ATM, BRCA1, BRCA2, CHEK2, MEN1, MLH1, ...
Tópico(s): Genetic Associations and Epidemiology
2017 - Springer Science+Business Media | Familial Cancer
The meioses of four sterile species in the genusAllium which develop bulblets in the inflorescences instead of seeds were ... reproduction (after the extirpation of bulblets). Byly srovnány meiose čtyř sterilních druhů roduAllium, u kterých se místo ... tapeta. UA. cepa var.viviparum byla shledána v meiose těžká aberační porucha, která už byla signalizována mitosou. ... oleraceum jde o triploidní a tetraploidní formy; v meiose se vytvářejí různé konfigurace—univalenty, bivalenty, trivalenty a ...
Tópico(s): Chromosomal and Genetic Variations
1972 - Institute of Experimental Botany of the Czech Academy of Sciences | Biologia Plantarum
... in four Pms2 -/- animals. A total of 1936 meioses were studied and compared to 1848 meioses from three Pms2 +/+ controls. A smaller study was ... the Msh2 knockout mutation. A total of 792 meioses were examined in the Msh2 -/- and 880 meioses in the Msh2 +/+ animal. Recombination fractions were not ...
Tópico(s): Cancer Genomics and Diagnostics
2002 - Oxford University Press | Journal of Heredity
... distances. By simulation studies, I investigated how many meioses are necessary to accurately estimate genetic map distances ... nonzero map distance was investigated. The number of meioses necessary to accurately estimate map distances depends greatly ... of 0.5 cM generated with 1,000 meioses, when marker heterozygosity was high (0.90), for ... to a unique position. For identical numbers of meioses and intermarker distances, genetic maps constructed from microsatellite ...
Tópico(s): Genomics and Phylogenetic Studies
2003 - Wiley | Genetic Epidemiology
Michael N. Weedon, Robert Hastings, Richard Caswell, Weijia Xie, Konrad Paszkiewicz, Thalia Antoniadi, Maggie Williams, Cath King, Lynn Greenhalgh, Ruth Newbury‐Ecob, Sian Ellard,
... sequencing of three affected individuals separated by eight meioses identified a single shared novel heterozygous variant, c. ... sequencing of three affected individuals separated by eight meioses identified a single shared novel heterozygous variant, c. ... IV-2, -7, and -14) separated by eight meioses were enriched from genomic DNA with Agilent's ... expected on the basis of the number of meioses separating these individuals). Testing of six additional affected ...
Tópico(s): Cellular Mechanics and Interactions
2011 - Elsevier BV | The American Journal of Human Genetics
Tiziana Altiero, Lorena Rebecchi,
... linkShare onFacebookTwitterLinked InRedditWechat Abstract Chromosome behaviour during male meioses has been studied in two bisexual amphimictic populations ... 2002). Consequently, karyotype and chromosome behaviour during male meioses have in this paper been subjected to a ... g and i). Bar: 5 μm. In male meioses of Macrobiotus richtersi, the six prophasic bivalents looked ... therefore without heterogametic sex) enchytraeid worms with achiasmatic meioses in both oogenesis and spermatogenesis (Christensen 1961). In ...
Tópico(s): Polar Research and Ecology
2004 - BioMed Central | Hereditas
Fabienne Clot, Marie‐Claude Babron, Selvaggia Percopo, Mara Giordano, F. Bouguerra, Françoise Clerget‐Darpoux, Luigi Greco, Jean‐Louis Serre, Marie‐Claude Fulchignoni‐Lataud,
... can be performant. As few as 30 informative meioses made it possible to demonstrate the implication of ... families, leading to a large number of informative meioses, 250 informative meioses for E8+47 and 304 for −14E9. Similar ... of a previous Italian sample (8) : 321 informative meioses for A281G and 360 for G2957C. Therefore, these ...
Tópico(s): Gastrointestinal disorders and treatments
2000 - Lippincott Williams & Wilkins | Journal of Pediatric Gastroenterology and Nutrition
Sabine Demotes-Mainard, Gérard Doussinault, JM Meynard,
... et de températures basses au moment de la méiose sur la viabilité du pollen et la nouaison ... des enceintes climatisées ont été soumises, au stade méiose, à des traitements combinant 2 niveaux de températures ( ... 3 j consécutifs, à différents stades encadrant la méiose.Le froid a légèrement réduit le nombre de ... essai, des parcelles ont été ombrées, à la méiose, avec un filet ne laissant pénétrer que 30% ...
Tópico(s): Agriculture, Plant Science, Crop Management
1995 - Springer Science+Business Media | Agronomie
Atif Adnan, Arwin Ralf, Allah Rakha, Nefeli Kousouri, Manfred Kayser,
... 1568 pairs of men related by 1-6 meioses. Of those, 45% were differentiated by one or ... 4096 pairs of men related by 1-20 meioses, compared to 9.6% with Y-filer based ... 7.9×10-2) based on 2741-3143 meioses, with an average rate across all 13 RM ... 2) based on 800 mutations from 44,922 meioses. The high haplotype diversity (h=0.9996) we ...
Tópico(s): Race, Genetics, and Society
2016 - Elsevier BV | Forensic Science International Genetics
David C. Rubinsztein, Jayne Leggo,
... while this phenomenon was not observed in female meioses. These data were compatible with meiotic drive. We ... that there was no segregation distortion in male meioses, while the smaller CAG allele was inherited in 57% of female meioses (p < 0.016). The pattern of inheritance of ... locus was significantly different when male and female meioses were compared (p = 0.0139). While previous data ...
Tópico(s): Mitochondrial Function and Pathology
1997 - BMJ | Journal of Medical Genetics
Mansoor Sarfarazi, Anne H. Child, Diliana Stoilova, Glen Brice, Trushna Desai, Ovidiu C. Trifan, Darmalingum Poinoosawmy, Ronald P. Crick,
... normal-tension open-angle glaucoma. Of the 42 meioses genotyped in this pedigree, 39 subjects (16 affected) ... 77 and 9.70. When only the affected meioses of this kindred were analyzed, LOD scores remained ... normal-tension open-angle glaucoma. Of the 42 meioses genotyped in this pedigree, 39 subjects (16 affected) ... 77 and 9.70. When only the affected meioses of this kindred were analyzed, LOD scores remained ...
Tópico(s): Retinal Development and Disorders
1998 - Elsevier BV | The American Journal of Human Genetics
Lue Ping Zhao, Ross L. Prentice, Fumin Shen, Li Hsu,
... markers collected from a relatively small number of meioses. Typically, this assessment has two objectives: to assess ... sizes. For a typical setup with 50 informative meioses on 50 markers uniformly distributed on a chromosome ... markers collected from a relatively small number of meioses. Typically, this assessment has two objectives: to assess ... sizes. For a typical setup with 50 informative meioses on 50 markers uniformly distributed on a chromosome ...
Tópico(s): Genetic Associations and Epidemiology
1999 - Elsevier BV | The American Journal of Human Genetics
Shahid Nazir, Atif Adnan, Rahat Abdul Rehman, Wedad Saeed Al-Qahtani, Abrar B. Alsaleh, Hussam S. Al-Harthi, Fatmah Ahmed Safhi, Reem Almheiri, Reem Lootah, Afra Alreyami, Imran Almarri, Chuan‐Chao Wang, Allah Rakha, Sibte Hadi,
... 1568 pairs of men covering one to six meioses from all over Pakistan and 216 male relatives ... rooted endogamous Sindhi pedigrees covering one to seven meioses. Here, we present 861 pairs of men from 62 endogamous pedigrees covering one to six meioses from the Punjabi population of Punjab, Pakistan. Mutations ... 5176 pairs of men related by 1–20 meioses, while Yfiler differentiation was 9.24% based on ...
Tópico(s): Genetic diversity and population structure
2022 - Multidisciplinary Digital Publishing Institute | Genes
Produção Nacional
Idémir Citadin, Maria do Carmo Bassols Raseira, Flávio Gilberto Herter, João Baptista da Silva, Alberto Centellas Quezada, Carlos Augusto Posser Silveira,
... trabalho foi testar a validade da técnica da meiose polínica como marcador do final da endodormência em ... desde 1º de maio até o final da meiose e desta até 10 e 50 % de florescimento. ... compreendidas entre 1º de maio e final da meiose. Pelos resultados dos dois anos de observação, verificou- ... atinjam o estádio de tétrades. O método da meiose polínica mostrou-se inadequado como marcador do final ...
Tópico(s): Growth and nutrition in plants
2002 - Sociedade Brasileira de Fruticultura | Revista Brasileira de Fruticultura
A.H. Sparrow, George M. Woodwell,
... parce que s'effectuant pendant et après la méïose: (1) le volume nucléaire est élevé; (2) le nombre de chromosomes est réduit après la méïose; (3) la vitesse de division nucléaire peut être faible, certaines espèces réclamant 2 ans entre la méïose et la maturation complète de la graine; (4) ...
Tópico(s): Chromosomal and Genetic Variations
1962 - Elsevier BV | Radiation Botany
... M. (1959). Zur Lokalisation der DNA während der Meiose in Mikrosporangium von Antirrhinum majus L. Mber. dt. ... F. (1962a). über Pinocytose-Mechanismen im Verlauf der Meiose bei Lycoperiscum und Cururbita unter Berücksichtigung ihrer Bedeutung ... F. (1962b). über Pinocytose-Mechanismen im Verlauf der Meiose bei Lycopersicum und Cucurbita unter Berücksichtigung ihrer Bedeutung ...
Tópico(s): Plant and fungal interactions
1967 - Wiley | Biological reviews/Biological reviews of the Cambridge Philosophical Society
... der K-Chromosomen ist in der Mitose und Meiose gegenüber dem der L-Chromosomen verschoben.Im Zygotän ... Chromosomen zusammensetzt, die sich in der Mitose und Meiose sowie in den Riesenkernen in einer Reihe von ...
Tópico(s): Plant Diversity and Evolution
1967 - University of Florence | Caryologia
Teresa Zelinski, Hiroko Kaita, Keith Johnson, Marilyn Moulds,
... at θ = 0.00) for paternal and maternal meioses combined, to LW (ẑ = 3.61 at θ = 0.00) in paternal meioses and less closely linked to SE (ẑ = ... θ = 0.09) for combined paternal and maternal meioses. Therefore, we propose a chromosome 19 location for ...
Tópico(s): Renal Diseases and Glomerulopathies
1990 - Wiley | Vox Sanguinis
A Bröcker-Vriends, E Briët, R. Quadt, Jos Dreesen, E.H. Bakker, R Claassen-Tegelaar, H. H. H. Kanhai, J. J. P. van de Kamp, P. Pearson,
... and the haemophilia A locus in 51 informative meioses. In one of these recombinant meioses crossing over had also occurred between the DX13 ... haemophilia A locus were found in 20 informative meioses. Segregation analysis of the polymorphic markers and the ...
Tópico(s): Prenatal Screening and Diagnostics
1987 - Thieme Medical Publishers (Germany) | Thrombosis and Haemostasis
John R. Yates, Nabeel A. Affara, D M Jamieson, M.A. Ferguson‐Smith, I Hausmanowa-Pétrusewicz, Jacek Zaremba, J Borkowska, Andrew Johnston, Kathleen Kelly,
... No recombination was observed in 11 phase known meioses informative for the factor VIII gene (F8C) and eight phase known meioses informative for DXS15 (DX13), giving maximum lod scores ... St14) showed one recombinant in 12 phase known meioses giving a maximum lod score of 2.62 ...
Tópico(s): Cancer-related gene regulation
1986 - BMJ | Journal of Medical Genetics
Brion S. Maher, Mary L. Marazita, Robert E. Ferrell, Michael M. Vanyukov,
... 13 studies, with a total of 571 informative meioses. The pooled odds ratio estimate was 1.41 ( ... five studies, with a total of 340 informative meioses, were combined yielding a pooled odds ratio of ... examining DAT1, with a total of 824 informative meioses, yielded a non-significant pooled odds ratio estimate ...
Tópico(s): Functional Brain Connectivity Studies
2002 - Lippincott Williams & Wilkins | Psychiatric Genetics
... a ‘hexad’ with six spores). From 565 sds meioses, we found six (1.1%) diads, 20 (3. ... bivalents (data not shown). These 8% of female meioses probably accounted for most of the female fertility ... in the sds mutant, as expected, many female meioses had only univalents (Figure 4E) and others had ...
Tópico(s): Plant Genetic and Mutation Studies
2002 - Springer Nature | The EMBO Journal
Produção Nacional
Revisado por pares
M. Ambo, Raquel de Lello Rocha Campos, A. S. A. M. T. Moura, Clarissa Boschiero, Millor Fernandes do Rosário, Mônica Corrêa Ledur, Kátia Nones, Luiz Lehmann Coutinho,
... with these markers. The number of total informative meioses per locus varied from 232 to 862, and the number of phase-known informative meioses from 0 to 764. Marker orders in the ... inverted. The reduced number of phase-known informative meioses for ADL0147 (150) may be pointed out as ...
Tópico(s): Animal Nutrition and Physiology
2008 - UNIVERSIDADE DE SÃO PAULO | Scientia Agricola
Emma Axelsson, Anders Albrechtsen, Aart van, Lingling Li, Hendrik‐Jan Megens, Addie Vereijken, R.P.M.A. Crooijmans, Martien A. M. Groenen, Hans Ellegren, Eske Willerslev, Rasmus Nielsen,
... share the potential to influence chromosome movement during meioses and make the following predictions based on the ... in 197 chicken families. By simulating fair Mendelian meioses, we locate chromosomal regions with statistically significant transmission ... hypothesis that centromeres and telomeres drive during female meioses in chicken.
Tópico(s): Genetic diversity and population structure
2010 - Springer Nature | Heredity
Produção Nacional
Revisado por pares
Maria Goreti Senna Corrêa, Judith Viégas, João Baptista da Silva, Paula Fernanda Vaz de Ávila, Gustavo Rossato Busato, Jaqueline Schneider Lemes,
... fases de metáfase, anáfase e telófase, tanto da meiose I (M I) como da meiose II (M II); 10 espécies foram estudadas quanto ...
Tópico(s): Plant Pathogens and Fungal Diseases
2005 - Sociedade Botânica do Brasil | Acta Botanica Brasilica