Produção Nacional
Revisado por pares
Liliane Z. Oliveira, Iria Luiza Gomes Farias, Melânia Lazzari Rigo, Werner Giehl Glanzner, Paulo Bayard Dias Gonçalves, Francine Carla Cadoná, Ivana Beatrice Mânica da Cruz, Júlia Gomes Farias, Marta Maria Medeiros Frescura Duarte, Luzia Franco, Gustavo Bertol, Elisângela Colpo, Patricia Chaves Brites, João Batista Teixeira da Rocha, Daniela Bitencourt Rosa Leal,
Background/Aim. The use of herbal products as a supplement to minimize the effects of chemotherapy for cancer treatment requires further attention with respect to the activity and toxicity of chemotherapy. Uncaria tomentosa extract, which contains oxindole alkaloids, is one of these herbal products. The objective of this study was to evaluate whether Uncaria tomentosa extract modulates apoptosis induced by chemotherapy exposure. Materials and Methods. Colorectal adenocarcinoma cells (HT29 cells) ...
Tópico(s): Traditional and Medicinal Uses of Annonaceae
2014 - Hindawi Publishing Corporation | Evidence-based Complementary and Alternative Medicine
Martin Dreyling, Jeanette K. Doorduijn, Eva Giné, Mats Jerkeman, Jan Walewski, Martin Hutchings, Ulrich Mey, Jon Riise, Marek Trněný, Vibeke Vergote, Melania Celli, Ofer Shpilberg, María Gomes da Silva, Sirpa Leppä, Linmiao Jiang, Christiane Pott, Wolfram Klapper, Döndü Gözel, Christian Schmidt, Michael Unterhalt, Marco Ladetto, Eva Hoster,
Tópico(s): T-cell and Retrovirus Studies
2022 - Elsevier BV | Blood
Produção Nacional
Revisado por pares
Lannuze Gomes De Andrade, Melânia Maria Ramos Amorim, Adriana Scavuzzi Carneiro da Cunha, Sonia Regina Figueiredo Leite, Suely Arruda Vital,
OBJETIVO: investigar os principais fatores associados a óbitos fetais na cidade de Recife, no Pernambuco, Brasil. MÉTODOS: foi realizado um estudo observacional do tipo caso-controle, incluindo casos atendidos no período de 1 de Junho de 2004 a 31 de Março de 2005. Foram incluídos 116 casos (natimortos) e 472 controles (nativivos), com parto assistido no serviço. Os casos foram identificados no livro de registro da sala de parto. A partir do nome e número de registro, foram identificadas as puérperas ...
Tópico(s): Injury Epidemiology and Prevention
2009 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia
Produção Nacional
Revisado por pares
Sandra de Andrade Heráclio, Alex Sandro Rolland Souza, Fátima Regina Gomes Pinto, Melânia Maria Ramos Amorim, Micheline de Lucena Oliveira, Paulo Roberto Eleutério de Souza,
<i>Objective:</i> To evaluate agreement between 3 methods for screening anal intraepithelial lesions: anal cytology, anoscopy and human papillomavirus (HPV) detection by PCR. <i>Study Design:</i> This prospective, cross-sectional study screened 324 women with cervical neoplasia for anal neoplasia. Agreement between methods was calculated using the ĸ coefficient. <i>Results:</i> Of 324 anal cytologies performed, 31.5% (n = 102) were found to be abnormal: low-grade anal lesions ...
Tópico(s): Colorectal Cancer Screening and Detection
2011 - Karger Publishers | Acta Cytologica
Produção Nacional
Ana Laura Carneiro Gomes Ferreira, Ariani Impieri de Souza, Melânia Maria Ramos Amorim,
OBJETIVOS: determinar a prevalência de disfunções sexuais femininas em mulheres atendidas no Centro de Atenção à Mulher do Instituto Materno Infantil Prof. Fernando Figueira, IMIP, utilizando os critérios de classificação da 4ª. edição do Manual Diagnóstico e Estatístico de Transtornos Mentais. MÉTODOS: estudo transversal, cujos dados foram obtidos em formulário estruturado, aplicado durante entrevista individual com 100 mulheres com idades entre 20 e 39 anos, no período de abril a maio de 2004. ...
Tópico(s): Adolescent Sexual and Reproductive Health
2007 - Instituto Materno Infantil de Pernambuco | Revista Brasileira de Saúde Materno Infantil
Produção Nacional
Revisado por pares
Viviane do Carmo Vasconcelos de Carvalho, Jamilly Lopes de Macêdo, Camilla Albertina Dantas de Lima, Maria da Conceição Gomes de Lima, Sandra de Andrade Heráclio, Melânia Maria Ramos Amorim, Maria de Mascena Diniz Maia, Ana Lúcia Figueiredo Porto, Paulo Roberto Eleutério de Souza,
Tópico(s): Cytokine Signaling Pathways and Interactions
2012 - Springer Nature | Molecular Biology Reports
Produção Nacional
Revisado por pares
Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda-Filho, Elizabeth B. Brickley, Thália Velho Barreto de Araújo, Ulísses Ramos Montarroyos, Marília Rosa Abtibol‐Bernardino, Marisa Márcia Mussi‐Pinhata, Geraldo Duarte, Conrado Milani Coutinho, Sílvia Fabiana Biason de Moura Negrini, Maria das Graças Costa Alecrim, Lucíola de Fátima Albuquerque de Almeida Peixoto, Maria Elisabeth Lopes Moreira, Andréa Zin, José Paulo Pereira Júnior, Karin Nielsen‐Saines, Celina Maria Turchi Martelli, Laura C. Rodrigues, Wayner Vieira de Souza, Liana O. Ventura, Consuelo Silva de Oliveira, Haroldo de Matos, E Serra, Luna Thais Souza Gomes, Maurício Lacerda Nogueira, Cássia Fernanda Estofolete, Denise Cristina Mós Vaz-Oliani, Saulo Duarte Passos, Antônio Fernandes Moron, Maria Manoela Duarte Rodrigues, Stéphanno Gomes Pereira Sarmento, Marília Dalva Turchi, Luiza Emylce Pelá Rosado, Ana Laura de Sene Amâncio Zara, Maria Bárbara Franco Gomes, Lavínia Schüler‐Faccini, Juliana Herrero-Silva, Melânia Maria Ramos Amorim, Adriana Oliveira Melo, Antônio José Lêdo Alves da Cunha, Arnaldo Prata‐Barbosa, Joffre Amim, Jorge Fonte de Rezende Filho, Juan Ignácio Calcagno, Luíz Carlos Júnior Alcântara, Breno Lima de Almeida, Cristina Barroso Hofer, Elizabeth S. Machado, Isadora Cristina de Siqueira, Flor Ernestina Martínez-Espinosa, Patrícia Brasil, Mariana de Carvalho Leal Gouveia, Maria de Fátima Pessoa Militão de Albuquerque, Jociele Malacarne, Luana Damasceno, Ana María Bispo de Filippis, Cleiton Silva Santos, Alan Oliveira Duarte, Pedro Fernando da Costa Vasconcelos, Mariana Borges Machado, Ana Paula Antunes Pascalicchio Bertozzi, Thamirys Cosmo Gillo Fajardo, Adriana Aparecida Tiraboschi Bárbaro, Ligia Conceição Marçal Assef, Clarice Pimentel, Thalita Fernandes de Abreu, Jousilene de Sales Tavares, Fabiana de Oliveira Melo, Talita de Toledo Lima, Maria das Graças Nunes Brasil, Cláudia Pereira Terças-Trettel, Giovanny Vinícius de Araújo França, Camila Bôtto-Menezes, Silvana Gomes Benzecry, Jaqueline Rodrigues Robaina, Mariana Barros Genuíno de Oliveira,
Knowledge regarding the risks associated with Zika virus (ZIKV) infections in pregnancy has relied on individual studies with relatively small sample sizes and variable risk estimates of adverse outcomes, or on surveillance or routinely collected data. Using data from the Zika Brazilian Cohorts Consortium, this study aims, to estimate the risk of adverse outcomes among offspring of women with RT-PCR-confirmed ZIKV infection during pregnancy and to explore heterogeneity between studies.We performed ...
Tópico(s): Viral Infections and Vectors
2022 - Elsevier BV | The Lancet Regional Health - Americas
Produção Nacional
Revisado por pares
Melânia Maria Ramos Amorim, Lidiane de Araújo Lima, Camila Vigolvino Lopes, Daniele Kelle Lopes de Araújo, Jéssica Guimarães Gomes Silva, Larissa Cynthia César, Adriana Suely de Oliveira Melo,
OBJETIVO: identificar os fatores associados à gestação na adolescência em um Estado do nordeste do Brasil. MÉTODOS: realizou-se um estudo de caso-controle na proporção de uma adolescente entre 10 e 19 anos (caso) para duas mulheres entre 20 e 35 anos (controles), totalizando 168 casos e 337 controles. As variáveis reprodutivas analisadas foram: escolaridade, situação marital, procedência, renda familiar per capita em reais, trabalho remunerado, escolaridade da mãe, presença do pai da adolescente em ...
Tópico(s): Food Security and Health in Diverse Populations
2009 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia
Produção Nacional
Revisado por pares
Samira M. Haddad, José Guilherme Cecatti, João Paulo Souza, Maria H. Sousa, Mary Ângela Parpinelli, Maria Laura Costa, Rodolfo C. Pacagnella, Ione Rodrigues Brum, Olímpio Barbosa Moraes Filho, Francisco Edson de Lucena Feitosa, Carlos A. S. Menezes, Everardo M. Guanabara, Joaquim L. Moreira, Frederico A. Peret, Luiza E. Schmaltz, Leila Katz, Antonio C. Barbosa Lima, Melânia Maria Ramos Amorim, Marília G. Martins, Dênis José Nascimento, Cláudio Sérgio Medeiros Paiva, Roger Denis Rohloff, Sérgio Martins Costa, Adriana Gomes Luz, Gustavo Lobato, Eduardo Cordioli, José Carlos Peraçoli, Nelson Lourenço Maia Filho, Silvana Maria Quintana, Fátima Aparecida Henrique Lotufo, Carla Betina Andreucci, Márcia Maria Auxiliadora de Aquino, Rosiane Mattar,
Objective . To assess quality of care of women with severe maternal morbidity and to identify associated factors. Method . This is a national multicenter cross-sectional study performing surveillance for severe maternal morbidity, using the World Health Organization criteria. The expected number of maternal deaths was calculated with the maternal severity index (MSI) based on the severity of complication, and the standardized mortality ratio (SMR) for each center was estimated. Analyses on the adequacy ...
Tópico(s): Global Maternal and Child Health
2014 - Hindawi Publishing Corporation | BioMed Research International
Produção Nacional
Revisado por pares
Fabia Pigatti Silva, Renato T. Souza, José Guilherme Cecatti, Renato Passini, Ricardo Porto Tedesco, Giuliane Jesus Lajos, Marcelo Luís Nomura, Patrícia Moretti Rehder, Tábata Z. Dias, Paulo F. Oliveira, Cleide M. Silva, Maria Laura Costa, Rodolfo C. Pacagnella, Samira M. Haddad, Vilma Zotarelli, Lucio T. Gurgel, Nelson Lourenço Maia Filho, Jacinta P. Mathias, Sérgio Tadeu Martins Marba, Ruth Guinsburg, Francisco Eulógio Martinez, Silvana Maria Quintana, Patrícia P. S. Melli, Francisco Edson de Lucena Feitosa, George N. Chaves, Ana Maria Feitosa Porto, Isabela Coutinho, Antonio C. Barbosa Lima, Elias F. Melo, Débora F. Leite, Melânia Maria Ramos Amorim, Adriana Suely Oliveira Melo, Fabiana O. Melo, Marília G. Martins, Marinea V. Nunes, Cláudio Sérgio Medeiros Paiva, Moisés Diôgo de Lima, Djacyr Magna Cabral Freire, Edson Gomes Tristão, Dênis José Nascimento, Carlos A. S. Menezes, Marcelo de Amorim Aquino, Janete Vettorazzi, Cintia E. Senger, Augusta M. B. Assumpção, Marcela A. F. Guedes, Maria Elizabeth Lopes Moreira, Vera Therezinha Medeiros Borges, Eduardo de Souza, Ana Cristina Perez Zamarian, Fátima Aparecida Henrique Lotufo, Kaliane P. Uzilin, Elvira A. O. Zanette, Carla Betina Andreucci, Tenílson Amaral Oliveira, Laércio R. Oliveira, Marcos Antonio Nogueira Santos, Nelson Sass, Mirian R. F. Silveira, Pedro R. Coutinho, Luciana T. Siqueira,
Abstract The association of body mass index (BMI) and gestational weight gain (GWG) with preterm birth (PTB) remains controversial in the literature. To evaluate different maternal BMI and GWG categories, according to the initial BMI, in relation to different PTB subtypes and perinatal outcomes, we conducted a secondary analysis of a multicentre cross-sectional study, along with a nested case-control study including PTB from 20 centers in Brazil. Pre-pregnancy underweight was associated with a lower ...
Tópico(s): Pregnancy and preeclampsia studies
2019 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Giulia de Miranda Taglialegna, Leila Katz, Larissa Mayara Aristóteles de Albuquerque, Milena Máximo de Freitas, Alexandre Jorge Gomes de Lucena, Melânia Maria Ramos Amorim,
Introducao As complicacoes aorticas durante a gestacao podem ocorrer em mulheres sem fatores de risco, porem, mais frequentemente, se associam com doencas do colageno (Sindromes de Marfan e Ehlers-Danlos) e malformacoes estruturais cardiacas (coarctacao e valva aortica bivalvular)., Na mulher abaixo dos 40 anos, aproximadamente metade desses eventos ocorre na gravidez, particularmente no terceiro trimestre, ou puerperio. E um evento extremamente raro, contabilizando 0,1% a 0,4% de todas as disseccoes ...
Tópico(s): Cardiac Structural Anomalies and Repair
2019 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Martin Dreyling, Jeanette K. Doorduijn, Eva Giné, Mats Jerkeman, Jan Walewski, Martin Hutchings, Ulrich Mey, Jon Riise, Marek Trněný, Vibeke Vergote, Ofer Shpilberg, María Gomes da Silva, Sirpa Leppä, Linmiao Jiang, Stephan Stilgenbauer, Andrea Kerkhoff, Ron D. Jachimowicz, Melania Celli, Georg Heß, Luca Arcaini, Carlo Visco, Tom van Meerten, Stefan Wirths, Pier Luigi Zinzani, Urban Novak, Peter Herhaus, Fabio Benedetti, Kristina Sonnevi, Christine Hanoun, Matthias Hänel, Judith Dierlamm, Christiane Pott, Wolfram Klapper, Döndü Gözel, Christian Schmidt, Michael Unterhalt, Marco Ladetto, Eva Hoster,
BackgroundAdding ibrutinib to standard immunochemotherapy might improve outcomes and challenge autologous stem-cell transplantation (ASCT) in younger (aged 65 years or younger) mantle cell lymphoma patients. This trial aimed to investigate whether the addition of ibrutinib results in a superior clinical outcome compared with the pre-trial immunochemotherapy standard with ASCT or an ibrutinib-containing treatment without ASCT. We also investigated whether standard treatment with ASCT is superior to ...
Tópico(s): Viral-associated cancers and disorders
2024 - Elsevier BV | The Lancet
Produção Nacional
Cristine Melania Gatto, Matheus Santos Gomes Jorge, Lia Mara Wibelinger, Telma Elita Bertolin, Marilene Rodrigues Portella, Marlene Doring,
Com o envelhecimento humano há aumento dos problemas de saúde apresentados pelos idosos e, muitas vezes, os familiares, ou os próprios indivíduos, optam por atendimentos especializados em geriatria, como é o caso das instituições de longa permanência para os idosos. Concomitante a isso, ocorre aumento do consumo de medicamentos por parte desta população, especialmente dos benzodiazepínicos, caracterizando, assim, a polifarmácia. Com base nisto, o objetivo deste estudo foi verificar a prevalência ...
Tópico(s): Youth, Drugs, and Violence
2019 - | Revista Brasileira de Ciências do Envelhecimento Humano
María Miguel-Garcés, Rita Gonçalves, Rodrigo Gutierrez‐Quintana, Patricia Álvarez, Katrin Beckmann, Emili Alcoverro, Melania Moioli, Edward Ives, Megan Madden, Sérgio A. Gomes, Evelyn M. Galban, Tim Bentley, Koen M. Santifort, An Vanhaesebrouck, Chiara Briola, Patrícia Montoliu, Unai Ibaseta, Inés Carrera,
Metabolic/neurodegenerative encephalopathies encompass a wide list of conditions that share similar clinical and magnetic resonance imaging (MRI) characteristics, challenging the diagnostic process and resulting in numerous tests performed in order to reach a definitive diagnosis. The aims of this multicentric, retrospective and descriptive study are: (I) to describe the MRI features of dogs and cats with metabolic/neurodegenerative encephalopathies; (II) to attempt an MRI recognition pattern classifying ...
Tópico(s): Alcoholism and Thiamine Deficiency
2024 - Frontiers Media | Frontiers in Veterinary Science
Produção Nacional
Revisado por pares
Luciano F. Drager, Geraldo Lorenzi‐Filho, Fátima Dumas Cintra, Rodrigo Pinto Pedrosa, Lia Bittencourt, Dalva Poyares, Carolina Gonzaga, Sônia Maria Togeiro, Rogério Santos‐Silva, Pedro Felipe Carvalhedo de Bruin, Glaucylara Reis Geovanini, Felipe N. Albuquerque, Wercules Oliveira, Gustavo Antônio Moreira, Linda Massako Ueno, Flávia Baggio Nerbass, Maria Urbana Pinto Brandão Rondon, Eline Rozária Ferreira Barbosa, Adriana Bertolami, Angêlo Amato Vincenzo de Paola, Betânia Braga Silva Marques, Camila Futado Rizzi, Carlos Eduardo Negrão, Carlos Henrique Gomes Uchôa, Cristiane Maki‐Nunes, Dênis Martinez, Edmundo Arteaga Fernández, Fabrizio Urbinati Maroja, Fernanda R. Almeida, Ivani C. Trombetta, Luciana Julio Storti, Luiz Aparecido Bortolotto, Marco Túlio de Mello, Melania Aparecida Borges, Mônica L. Andersen, Natanael de Paula Portilho, Paula Macedo, Rosana Alves, Sérgio Tufik, Simone Chaves Fagondes, Thaís Telles Risso,
1o Posicionamento Brasileiro sobre o Impacto dos Disturbios de Sono nas Doencas Cardiovasculares da Sociedade Brasileira de Cardiologia
Tópico(s): Global Public Health Policies and Epidemiology
2018 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Luciano Silva Gomes, Maria Lúcia Adriana Silva Gomes, Melânia Kássia Barbosa e Silva, Francisco Gilson Rebouças Pôrto,
Expõe o relato de experiência da participação de pós-graduandos do Curso de Especialização em Ensino de Comunicação / Jornalismo: Temas Contemporâneos, da Universidade Federal do Tocantins (UFT), como ministrantes de oficinas no Curso de Formação de “Assessores de Comunicação” do Colégio da Polícia Militar (CPM) de Araguaína, realizado no primeiro semestre de 2016, por meio de projeto de extensão acadêmica “Escola Livre de Jornalismo”. O curso está previsto no sistema de Administração Compartilhada do ...
Tópico(s): Education and Public Policy
2017 - FUNDACAO UNIVERSIDADE FEDERAL DO TOCANTINS | Aturá - Revista Pan-Amazônica de Comunicação
Produção Nacional
Revisado por pares
Ana Paula Souza Mambri, Jerônimo Luiz Andriolo, Melânia Palermo Manfron, Suany Maria Gomes Pinheiro, Francieli Lima Cardoso, Myriam Galvão Neves,
RESUMO O objetivo deste trabalho foi avaliar o efeito de sucessivas epocas de colheita e do sombreamento na producao de fitomassa, rendimento e composicao fitoquimica do oleo volatil de folhas e inflorescencias de Lavandula dentata L. em cultivo sem solo. As plantas foram cultivadas em sistema fechado de cultivo sem solo no Departamento de Fitotecnia da UFSM. O plantio foi feito em 8 de marco de 2014 e foram realizadas tres coletas sucessivas aos 150, 213 e 320 dias apos o plantio, no inverno, ...
Tópico(s): Agricultural and Food Sciences
2018 - Associação Brasileira de Olericultura | Horticultura Brasileira
Produção Nacional
Revisado por pares
Gelson Garcia Dutra, Juliana Marques Weykamp, Rosiele Gomes Flores, Melania Sartori Villani, Dápine Neves da Silva, Kelen da Costa Pompeu, Diéssica Roggia Piexak, Márcio André Gayer Martins, Luana da Silva Soares, Hedi Crecência Heckler de Siqueira,
Objetivo: identificar na produção científica as ações desenvolvidas pelo enfermeiro no Serviço de Atendimento Móvel de Urgência. Método: Revisão de escopo com busca na base de dados: Medical Literature Analysis and Retrieval System Online (MEDLINE), na Literatura Latino-Americana e do Caribe em Ciências da saúde (LILACS), Scientific Electronic Library Online (SCIELO), Banco de dados Enfermagem (BDENF), e na National Library of Medicin (PubMed), utilizando descritores controlados, no período de 2017 a ...
Tópico(s): Healthcare during COVID-19 Pandemic
2022 - Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências | Research Society and Development
James Glasbey, Adesoji Ademuyiwa, Adewale Adisa, Ehab Alameer, Alexis Arnaud, Faris Ayasra, José Azevedo, Ana Minaya‐Bravo, Ainhoa Costas‐Chavarri, John Edwards, Muhammed Elhadi, Marco Fiore, Christina Fotopoulou, Gaetano Gallo, Dhruva Ghosh, Ewen A. Griffiths, Ewen M. Harrison, Peter Hutchinson, Ismaïl Lawani, Samuel Lawday, Hans Lederhuber, Sezai Leventoğlu, Elizabeth Li, Gustavo Mendonça Ataíde Gomes, Harvinder Mann, Ella J Marson, Janet Martin, Dennis Mazingi, Kenneth A McLean, María Marta Modolo, Rachel Moore, Dion Morton, Faustin Ntirenganya, Francesco Pata, Maria Picciochi, Peter Pockney, Antonio Ramos‐De la Medina, Keith Roberts, April Camilla Roslani, Rajkumar Kottayasamy Seenivasagam, Richard Shaw, Joana Filipa Ferreira Simões, Neil Smart, Grant D. Stewart, Richard Sullivan, Sudha Sundar, Stephen Tabiri, Elliott H Taylor, Raghavan Vidya, Dmitri Nepogodiev, Aneel Bhangu, James C Glasbey, Kenneth A McLean, Dmitri Nepogodiev, Ewen M. Harrison, Aneel Bhangu, Dmitri Nepogodiev, Kwabena Siaw-Acheampong, Ruth Benson, Edward Bywater, Daoud Chaudhry, Brett E Dawson, Jonathan P Evans, James C Glasbey, Rohan R Gujjuri, Emily Heritage, Conor Jones, Sivesh K. Kamarajah, Chetan Khatri, Rachel A Khaw, James M Keatley, Andrew T. Knight, Samuel Lawday, Elizabeth Li, Harvinder Mann, Ella J Marson, Kenneth A McLean, Siobhan C. McKay, Emily Mills, Gianluca Pellino, Maria Picciochi, Elliott H Taylor, Abhinav Tiwari, Joana F F Simoes, Isobel M Trout, Mary L Venn, Richard Wilkin, Aneel Bhangu, James C Glasbey, Neil Smart, Ana Minaya‐Bravo, Jonathan P Evans, Gaetano Gallo, Susan Moug, Francesco Pata, Peter Pockney, Salomone Di Saverio, Abigail Vallance, Dale Vimalchandran, Ewen A. Griffiths, Sivesh K. Kamarajah, Richard Evans, Philip Townend, Keith Roberts, Siobhan C. McKay, John Isaac, Sohei Satoi, John Edwards, Aman S. Coonar, Adrian Marchbank, Edward Caruana, Georgia R. Layton, Akshay J. Patel, Alessandro Brunelli, Samuel Ford, Anant Desai, Alessandro Gronchi, Marco Fiore, Max Almond, Fabio Tirotta, Sinziana Dumitra, Angelos G. Kolias, Stephen J. Price, Daniel M. Fountain, Michael D. Jenkinson, Peter Hutchinson, Hani J. Marcus, Rory J. Piper, Laura Lippa, Franco Servadei, Ignatius Esene, Christian F. Freyschlag, Iuri Santana Neville, Gail Rosseau, Karl Schaller, Andreas K. Demetriades, Faith C. Robertson, Alexander Alamri, Richard Shaw, Andrew Schache, Stuart C. Winter, Michael Ho, Paul Nankivell, Juan Rey Biel, Martin Batstone, Ian Ganly, Raghavan Vidya, Alex Wilkins, Jagdeep Singh, Dinesh Thekinkattil, Sudha Sundar, Christina Fotopoulou, Elaine Leung, Tabassum Khan, Luis Chiva, Jalid Sehouli, Anna Fagotti, Paul A. Cohen, Murat Gutelkin, Rahel Ghebre, Thomas O. Konney, René Pareja, R.E. Bristow, Sean C. Dowdy, TS Shylasree, Rajkumar Kottayasamy Seenivasagam, Joe Ng, Keiichi Fujiwara, Grant D. Stewart, Benjamin W. Lamb, Krishna Narahari, Alan McNeill, Alexandra J. Colquhoun, John McGrath, Steve Bromage, Ravi Barod, Veeru Kasivisvanathan, Tobias Klatte, Joana F F Simoes, Tom Abbott, Sadi A. Abukhalaf, Michel Adamina, Adesoji Ademuyiwa, Arnav Agarwal, Murat Akkulak, Ehab Alameer, Derek Alderson, Felix Alakaloko, Markus Albertsmeier, Osaid Alser, Muhammad Alshaar, Sattar Alshryda, Alexis Arnaud, Knut Magne Augestad, Faris Ayasra, José Azevedo, Brittany Bankhead-Kendall, Emma Barlow, David Beard, Ruth Benson, Ruth Blanco‐Colino, Amanpreet Brar, Ana Minaya‐Bravo, Kerry Breen, Chris Bretherton, Igor Lima Buarque, Josh Burke, Edward Caruana, Mohamad K. Abou Chaar, Sohini Chakrabortee, Peter Christensen, Daniel Cox, Moisés Cukier, Miguel F Cunha, Giana H. Davidson, Anant Desai, Salomone Di Saverio, Thomas M Drake, John Edwards, Muhammed Elhadi, Sameh Hany Emile, Shebani Farik, Marco Fiore, J.E.F. Fitzgerald, Samuel Ford, Tatiana Garmanova, Gaetano Gallo, Dhruva Ghosh, Gustavo Mendonça Ataíde Gomes, Gustavo Grecinos, Ewen A. Griffiths, Magdalena Gruendl, Constantine Halkias, Ewen M. Harrison, Intisar Hisham, Peter Hutchinson, Shelley Hwang, Arda Işık, Michael D. Jenkinson, Pascal Jonker, Haytham M.A. Kaafarani, Debby Keller, Angelos G. Kolias, Schelto Kruijff, Ismaïl Lawani, Hans Lederhuber, Sezai Leventoğlu, Andrey Litvin, Andrew P. Loehrer, Markus Löffler, Maria Aguilera Lorena, María Marta Modolo, Piotr Major, Janet Martin, Hassan Mashbari, Dennis Mazingi, Symeon Metallidis, Ana Minaya‐Bravo, Helen Mohan, Rachel Moore, David Moszkowicz, Susan Moug, Joshua S Ng-Kamstra, Mayaba Maimbo, Ionuț Negoi, Milagros Niquen-Jimenez, Faustin Ntirenganya, Maricarmen Olivos, Salah Eddine Oussama Kacimi, Oumaima Outani, Marie Dione Parreno-Sacdalanm, Francesco Pata, Carlos J. Pérez-Rivera, Thomas Pinkney, Willemijn Y. van der Plas, Peter Pockney, Ahmad Uzair Qureshi, Dejan Radenković, Antonio Ramos‐De la Medina, Toby Richards, Keith Roberts, April Camilla Roslani, Martin Rutegård, Juan José Segura‐Sampedro, Irène Santos, Sohei Satoi, Raza Sayyed, Andrew Schache, Andreas A. Schnitzbauer, Justina O. Seyi‐Olajide, Neil Sharma, Catherine A. Shaw, Richard Shaw, Sebastian Shu, Kjetil Søreide, Antonino Spinelli,
BackgroundSurgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery during the COVID-19 pandemic in periods of lockdown versus light restriction.MethodsThis international, prospective, cohort study enrolled 20 006 adult (≥18 years) patients from 466 hospitals in 61 countries with 15 cancer types, who had a decision for curative ...
Elsevier BV
I Dajti, José Ignacio Valenzuela, L Boccalatte, Nicolas A Gemelli, Dantwan Smith, Nagendra N. Dudi‐Venkata, Hidde M. Kroon, Tarik Sammour, Matthew M. Roberts, D Mitchell, K Lah, A Pearce, Dion Morton, Amanda Dawson, A Drane, Claire Sharpin, Ramesh Nataraja, Maurizio Pacilli, Daniel Cox, Vijayaragavan Muralidharan, Georgina Riddiough, Edmund Clarke, Wael Jamel, Kirby R. Qin, Peter Pockney, Daron Cope, N Egoroff, Natalie Lott, Sven Putnis, S De Robles, Zen Yang Ang, Martin Mitteregger, Stefan Uranitsch, Marjorie Stiegler, Gerald Seitinger, Felix Aigner, D B Lumenta, Sebastian P. Nischwitz, Erika Richtig, Mauro Pau, Petra Srekl-Filzmaier, Nicolas Eibinger, Birgit Michelitsch, Melanie Fediuk, A Papinutti, Geoffrey Seidel, Joseph Kahn, Tina Cohnert, Donna A. Messner, F. Ofner, J Presl, Márta Varga, Michael Weitzendorfer, K. Emmanuel, Alf-Dorian Binder, Marc Zimmermann, S Holawe, Emeka Nkenke, Christoph Grimm, M Kranawetter, Ashrarur Rahman Mitul, Nazmul Islam, Syed S. Karim, Niels Komen, Sven Putnis, S De Robles, Emily Ang, Herbert De Praetere, Tim Tollens, G Schols, C. Smets, Laura Haenen, Jorien Quintens, K Van Belle, Gabriëlle H. van Ramshorst, Piet Pattyn, Liesbeth Desender, Thomas Martens, Dirk Van de Putte, Philip Lerut, Aude Grimonprez, Marcus L.F. Janssen, G. De Smul, P. Wallaert, Jef Van den Eynde, Wouter Oosterlinck, Raf Van den Eynde, An Sermon, A. Boeckxstaens, Anne-Laure Cordonnier, Jeroen De Coster, Joris Jaekers, Constantinus Politis, Marc Miserez, Nicolas Duchateau, Charles de Gheldere, Nicolas Flamey, Piet Pattyn, A Christiano, Benedetta Guidi, A L Minussi, Sílvia Castro, Willy Okoba, F H R Maldonado, Paulo Oliveira, Tiago Antônio Baldasso, Luciano Marques dos Santos, Gustavo Mendonça Ataíde Gomes, Igor Lima Buarque, Laércio Pol Fachin, Tainá Santos Bezerra, Aldo Vieira Barros, A Silva, A L S Leite, Daniela Silvestre, C Carvalho Ferro, M S Araujo, L. M. Lopes, Pâmela dos Santos Bittencourt Damasceno, D H S Araujo, Gustavo Andreazza Laporte, M Salem, Marco Guimarães-Filho, Lucas Souto Nacif, Ronald Luiz Gomes Flumignan, Luís CU Nakano, Danielle Akemi Bergara Kuramoto, A L S Aidar, Mariana Raffo Pereda, R M Correia, Brena Costa Santos, Alzira Alves de Siqueira Carvalho, Jorge Eduardo de Amorim, Henrique Jorge Guedes Neto, Libnah Leal Areias, Álvaro Francisco Lopes de Sousa, Carolina Dutra Queiroz Flumignan, W G Lustre, Doris Hupfeld Moreno, Nathana Prado de Almeida Barros, José Carlos Costa Baptista‐Silva, Leandro Luongo de Matos, L P Kowaski, Marco Aurélio Vamondes Kulcsar, KS Nunes, Marcos F.S. Teixeira, Rafael Leite Nunes, Takeshi Ijichi, N. J. Kim, Ana Beatriz Pontes Marreiro, Bárbara Müller, Joseph Awada, Glauco Baiocchi, Luiz Paulo Kowalski, JG Vartanian, Fabiana B. Makdissi, Samuel Aguiar, Nuno Marques, Genival Barbosa de Carvalho, Tatiana Marques, Emne Ali Abdallah, Charles Edouard Zurstrassen, Jamie Gross, Stênio de Cássio Zéqui, Bruna Tirapelli Gonçalves, Sigrid de Sousa dos Santos, João Pedreira Duprat Neto, Felipe José Fernández Coimbra, Rafael De Cicco, Flávio Roberto Takeda, Ivan Cecconello, Ulysses Ribeiro, A Gatti, R Oliva, C Nardi, Mihail Slavchev, Boyko Atanasov, Nikolay Belev, Angela Dell, David L. Bigam, Khaled Dajani, S Al Riyami, Janet Martin, Davy Cheng, Hua Yang, A Fayad, François Martin Carrier, E. Amzallag, Joannie Desroches, Marie T. Ruel, Natasha Caminsky, Marylise Boutros, J Moon, E. G. C. Wong, Tsafrir Vanounou, Jonathan Pelletier, S Wong, Elie Girsowicz, J Bayne, Daniel I. Obrand, Heather L. Gill, Oren K. Steinmetz, Kenneth MacKenzie, Marie‐Amélie Lukaszewski, Ghader Jamjoum, Philippe Richebé, Olivier Verdonck, S Discepola, Nathalie Godin, M. Idrissi, Vincent Lecluyse, Geneviève Côté, Sebastian Demyttenaere, Richard Garfinkle, Marylise Boutros, A Kouyoumdjian, Marylise Boutros, Sinziana Dumitra, J Moon, E. G. C. Wong, Kosar Khwaja, Lan Luo, Marie‐Amélie Lukaszewski, Heather L. Gill, Gerald J. Berry, Adrienne Liberman, Elie Girsowicz, J Bayne, Daniel I. Obrand, Oren K. Steinmetz, Kenneth MacKenzie, Severin Schmid, Jonathan Spicer, Mehdi Farsi, Jad Abou‐Khalil, Étienne J. Couture, Seyede Momeneh Mohammadi, Hugo Tremblay, Nathalie Gagné, Anne Bergeron, Alexis F. Turgeon, O. Costerousse, David Bellemare, C. Babin, Catherine Blier, M L Wood, Amit Persad, Gary Groot, Hau Pham, Frédérick D’Aragon, Élaine Carbonneau, Maude Bouchard, Marie-Hélène Masse, F Pesant, Jennifer Héroux, Paul J. Karanicolas, Julie Hallet, A Nadler, Avery B. Nathens, M Ko, A Brar, Kelly Mayson, B Kidane, Sadeesh Srinathan, M Escudero, Janette T. Reyes, María Marta Modolo, P Ramirez Nieto, Rodrígo Sepúlveda, A Bolbarán, Andrés Molero‐Chamizo, Isaac Ruiz, Gabriel Reyes, Rafael Salas, Cristóbal Suazo, Rodrigo Muñoz, E Grasset, Martín Inzunza, Nicolás Besser, M J Irarrázaval, Cristián Jarry, Felipe Bellolio, C A Romero Manqui, M Ruiz Esquide, T. Fuentes, José Luis Campos, Carlos J. Pérez-Rivera, Payton Cabrera, Raúl Eduardo Pinilla Morales, Óscar Guevara, LJ Jimenez Ramirez, B G Velasquez Cuasquen, Damián Mora, A Bonilla, Sandra Diaz, E Manrique,
To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in surgical patients with SARS-CoV-2. We found that patient rather than operation factors were the best predictors and used these to create the COVIDsurg Mortality Score (https://covidsurgrisk.app). Our data demonstrates that it is safe to restart a wide ...
Oxford University Press
L. Harms, Arlie B. Bock, W Jänisch, José M. Valdueza, Jeffrey C. Weber, I. Link, Jacques De Keyser, A. Goossens, N. Wilczak, Christian Vedeler, Line Bjørge, E. Uvestad, Gabriele Conti, Kirsten M. Williams, Lionel Ginsberg, Saima Rafique, С. И. Рапопорт, Norman L. Gershfeld, G De La Meilleure, Luc Crevits, Jürgen Faiss, N. Heye, J. Blanke, Anna Sackmann, Oliver Kastrup, R. Doornbos, H. Bart van der Worp, L. Jaap Kappelle, Přemysl Bar, C. A. Davie, Gerry J. Barker, D. Brenton, D. H. Miller, Alan J. Thompson, FRANK B. BLOCK, Markus Schwarz, L. Delodovici, Fabio Baruzzi, G. Bonaldi, Amabile Borges Dario, Angela Marra, A. Mercuri, F. Dworzak, Paolo Cavallari, Paolo Confalonieri, Marco A. L. Zuffi, Carlo Antozzi, F. Cornelio, F. Baldissera, B. Chassande, Abdol A. Ameri, B. Eymard, M Poisson, A Vérier, P Brunet, Stefano Congia, P. L. Murgia, Antonino Cannas, Giuseppe Borghero, S. Uselli, Gisa Mellino, R. Ferrai, R. Lampis, Roberto Massa, B. Muzzetto, F. Giannini, S. Rossi, R. Cioni, Carlo D’Aniello, Alessia Guarneri, N. Battistini, Federico Ceriani, Antonio Santo, M. Poloni, John F. de Campo, F. Iglesias, M. V. Guitera, Castro Farinas, Julio Pascual, C Leno, José Berciano, I. W. Thorpe, B. E. Kendall, W. I. McDonald, Antoine Moulignier, Françoise Dromer, M. Baudrimont, Benoît Dupont, Joël Gozlan, Mohamed Amrani, Joan Petit, E Roullet, Roberto Sterzi, R. Causaran, Alessandro Protti, Marco Riva, F. Erminio, O. Arena, Fernando Villa, Elio Maccagnano, Maria Consolata Miletta, Francesco Spinelli, Tamir Ben‐Hur, J. Weidenfeldl, N.S.V.M. Prabhakara Rao, C. C. Chari, P. Laforet, Sophie Matheron, Don Adams, Ph. Chemouilli, M Desi, G. Said, P Davous, Françoise Lionnet, M. Pulik, Philippe Genet, Flore Rozenberg, L Cartier, Joaquim Castilló, J. G., Roque Villagra, L. de Saint Martin, Florence Mahieux, M. J. Manifacier, Kélli Renata Corrêa de Mattos, Catarina Queirós, L. Publio, V. Vinhas, A. C. PeÇanha-Martins, Antonieta Melo, U. Liska, U. Zifko, Herbert Budka, M. Drlicek, W. Grisold, Roland Kaufmann, R. Kaiser, Martin Czygan, Inês Afonso Gomes, Nicholas Jones, Sérgio Pereira da Cunha, E. Katiane EmbiruÇu, Verónica M. Vieira, ISABELLY BARROS DE ARAÚJO, Mónica Alexandra, A. C. Silva Ferreira, João Goês, P. Chemouilli, Israel‐Biet, Henri Masson, Carol Lacroix, J. Gasnault, B. Hildebrandt-Müller, Patrick Oschmann, Paul Krack, Wulf R. Willems, W. Dorndorf, Valéria Leite de Freitas, Aline Gomes Bittencourt, Daniel Fernandes, Matheus Hipólito do Nascimento, Mateus Dornelles Severo, D. Moraes, Maximilian Müller, K. Hasert, S. Merkelbach, К. Schimrigk, Bob W. van Oosten, Matthew Lai, C. H. Polman, Frits W. Bertelsmann, Suzanne Hodgkinson, Philippe Cabre, Laura Volpe, Didier Smadja, Jean Paul Vernant, H. Villaroya, K. Violleau, Amena Ben Younes‐Chennoufi, Natascha Baumann, P. Villanueva-Hemandez, J. Ballabriga, E. Basart, T. Arbizu, J. Perez-Serra, F. Vinuels, J.M. Girón, J Castilla, L. M. Redondo, G Izquierdo, Klaus Lauer, A.E. Henneberg, N. Bittmann, Daniel C. Link, Kurt H. Wollinsky, R. Möbner, Klaus Faßbender, J. Kuhnen, A. Schwartz, Michael G. Hennerici, Aaron Miller, O. Lider, Oded Abramsky, H. Weiner, Herman Leroy Offner, A. A. Vanderbark, E. Paoino, Enrico Fainardi, M. C. Addonizio, P Ruppi, Maria Rosalia Tola, Enrico Granieri, M Carreras, V. Sazdovitch, Anne Joutel, M H Verdier-Taillefer, O. Heinzlef, Celine M. Radder, Elisabeth Tournier‐Lasserve, R. E. Brenner, P. M. G. Munro, Steven Williams, Julie Bell, Clive Hawkins, Massimo Filippi, A. Campi, Vincent Dousset, N. Canal, Giacomo P. Comi, Jiahong Zhu, Frank Weber, R. Retska, Jane List, Linlin Zhang, M. Brock, Martin Klein, J. J. Heimans, E. A. van der Veen, A. B. M. F. Karim, M. Sarazin, N. Argentino, J. Y. Delattre, P. Derkinderen, Brigitte Buchwald, Gabriella Torres Schröter, G. Serve, Christina Franke, B. Conrad, Neil Kitchen, D.G.T. Thomas, Amanda Forman, Kie Kian Ang, Raymond R. Price, C. Stephens, Andrea Salmaggi, R. Nermni, Antonio Silvani, M. G. Forno, Roberto Luksch, A. Boiardi, H. Grzelec, C Fryze, P. E. Nowacki, B. Zdziarska, Marc Sanson, Patrick Mérel, Stephen Richard, Guy A. Rouleau, Gwenda Thomas, N. K. Olsen, P. Pfeiffer, Niels Egund, Søren M. Bentzen, Lars Johannesen, K. Mondrup, Carl H. Rose, Beata Zyluk, E. Wondrusch, Oscar Berger, N. Fast, K. A. Jellinger, Karlsruhe Lindner, A. Urman, Jean-Luc Thibault, C Duyckaerts, Helmer Strik, Bettina Müller, Elisa Richter, P. Krauseneck, Astrid Steinbrecher, M. Schabet, Christopher P. Hess, M. Bamberg, J. Dichgans, Carl Counsell, Chandler McLeod,
Cytomegalovirus (CMV) causes several neurological diseases in the late stages of AIDS, but their ante-mortem diagnosis is problematic.Clinical criteria (defining a presumptive diagnosis) and polymerase chain reaction $4 (PCR) assay from cerebrospinal fluid (CSF) were blindly used to predict the involvement of CMV in neurological disorders of 164 consecutive AIDS patients undergoing a lumbar puncture.During the follow-up, a definite diagnosis based on viral culture of CSF, clinical outcome and/or CNS ...
Springer Science+Business Media
Produção Nacional
Anna Caroline Feitosa Lima, Bárbara Freire de Oliveira, Wilma Karla Vasconcelos Da Silva, Karina Soares do Bonfim, Martha Maria Gomes Nóbrega, Ynis Thaciane Felix Da Silva, Josilene de Assis Cavalcante, Melânia Lopes Cornélio,
Estudos fitoquímicos mostram que as folhas do noni contêm uma variedade de componentes químicos, incluindo terpenóides, fitoesteróis, ácidos graxos, iridóides glicosídicos, flavonóides glicosídeos, entre outros. A secagem é uma maneira de aumentar o tempo de vida útil de produtos, uma vez que ao se reduzir a atividade de água, diminui-se o risco de proliferação de microrganismos. O objetivo desta pesquisa foi avaliar a secagem em camada de espuma da folha do noni para obtenção da sua forma em pó. ...
Tópico(s): Morinda citrifolia extract uses
2024 - Servicios Academicos Intercontinentales | OBSERVATÓRIO DE LA ECONOMÍA LATINOAMERICANA
Yihan Shao, Zhengting Gan, Evgeny Epifanovsky, Andrew T. B. Gilbert, Michael Wormit, Jörg Kußmann, Adrian W. Lange, Andrew Behn, Jia Deng, Xintian Feng, Debashree Ghosh, Matthew Goldey, Paul R. Horn, Leif D. Jacobson, Ilya Kaliman, Rustam Z. Khaliullin, Tomasz Kuś, Arie Landau, Jie Liu, Emil Proynov, Young Min Rhee, Ryan M. Richard, Mary A. Rohrdanz, Ryan P. Steele, Eric J. Sundstrom, H. Lee Woodcock, Paul M. Zimmerman, Dmitry Zuev, Ben Albrecht, Ethan Alguire, Brian Austin, Gregory J. O. Beran, Yves Bernard, Eric Berquist, Kai Brandhorst, Ksenia B. Bravaya, Shawn T. Brown, David Casanova, C C Chang, Yunqing Chen, Siu Hung Chien, Kristina D. Closser, Deborah L. Crittenden, Michael Diedenhofen, Robert A. DiStasio, Hainam Do, Anthony D. Dutoi, Richard G. Edgar, Shervin Fatehi, László Füsti-Molnár, An Ghysels, Anna Golubeva-Zadorozhnaya, Joseph Gomes, Magnus W. D. Hanson‐Heine, Philipp H. P. Harbach, Andreas Hauser, Edward G. Hohenstein, Zachary C. Holden, Thomas‐C. Jagau, Hyunjun Ji, Benjamin Kaduk, Kirill Khistyaev, Jaehoon Kim, Jihan Kim, Rollin A. King, Phil Klunzinger, Dmytro Kosenkov, Tim Kowalczyk, Caroline M. Krauter, Ka Un Lao, Adèle D. Laurent, Keith V. Lawler, Sergey V. Levchenko, Ching Yeh Lin, Fenglai Liu, Ester Livshits, Rohini C. Lochan, Arne Luenser, Prashant Uday Manohar, Samuel F. Manzer, Shan-Ping Mao, Narbe Mardirossian, Aleksandr V. Marenich, Simon A. Maurer, Nicholas J. Mayhall, Eric Neuscamman, C. Melania Oana, Roberto Olivares‐Amaya, D.P. O'Neill, John Parkhill, Trilisa M. Perrine, Roberto Peverati, Alexander Prociuk, Dirk R. Rehn, Edina Rosta, Nicholas J. Russ, Shaama Mallikarjun Sharada, Sandeep Sharma, David W. Small, Alexander J. Sodt, Tamar Stein, David Stück, Yu-Chuan Su, Alex J. W. Thom, Takashi Tsuchimochi, Vitalii Vanovschi, Leslie Vogt-Maranto, Oleg A. Vydrov, Tao Wang, Mark A. Watson, Jan Wenzel, Alec F. White, Christopher F. Williams, Jun Yang, Sina Yeganeh, Shane R. Yost, Zhi‐Qiang You, Igor Ying Zhang, Xing Zhang, Yan Zhao, Bernard R. Brooks, Garnet Kin‐Lic Chan, Daniel M. Chipman, Christopher J. Cramer, William A. Goddard, Mark S. Gordon, Warren J. Hehre, Andreas Klamt, Henry F. Schaefer, Michael W. Schmidt, C. David Sherrill, Donald G. Truhlar, Arieh Warshel, Xin Xu, Alán Aspuru‐Guzik, Roi Baer, Alexis T. Bell, Nicholas A. Besley, Jeng‐Da Chai, Andreas Dreuw, Barry D. Dunietz, Thomas R. Furlani, Steven R. Gwaltney, Chao‐Ping Hsu, Yousung Jung, Jing Kong, Daniel S. Lambrecht, WanZhen Liang, Christian Ochsenfeld, Vitaly A. Rassolov, Lyudmila V. Slipchenko, Joseph E. Subotnik, Troy Van Voorhis, John M. Herbert, Anna I. Krylov, Peter M. W. Gill, Martin Head‐Gordon,
A summary of the technical advances that are incorporated in the fourth major release of the Q-Chem quantum chemistry program is provided, covering approximately the last seven years. These include developments in density functional theory methods and algorithms, nuclear magnetic resonance (NMR) property evaluation, coupled cluster and perturbation theories, methods for electronically excited and open-shell species, tools for treating extended environments, algorithms for walking on potential surfaces, ...
Tópico(s): Catalysis and Oxidation Reactions
2014 - Taylor & Francis | Molecular Physics
M. Veitenhansl, K. Stegner, F. X. Hierl, C. Dieterle, Hermann Feldmeier, B Gutt, R. Landgraf, Adam Garrow, Loretta Vileikyte, Andrew H. Findlow, Carrie Waterman, A. J. M. Boulton, Kshitij Shankhdhar, LK Shankhdhar, U Shankhdhar, Nina L. Petrova, A FOSTER, Michael Edmonds, Roberto Ferraresi, C. Caravaggi, R. De Giglio, Paola Cavaiani, Ileana Pogliaghi, Elena Sommariva, Irwin Katz, A W Harlan, Bresta Miranda-Palma, Luz Prieto-Sanchez, David G. Armstrong, John H. Bowker, Mark S. Mizel, Simona Cernea, Jay Wohlgelernter, Miriam Kidron, Pramila Modi, Itamar Raz, Ehud Arbit, Leszek Nosek, Christoph Kapitza, Philip R. Beckett, R. Gelfand, Marcel Goldberg, Tim Heise, Marcia A. Testa, Ralph R. Turner, J. F. Hayes, Richard E. Scranton, D. C. Simonson, Yang Yuan, Y.-J. Hsu, Ortwin Naujok, Flavio Francini, Anne Jörns, Markus Tiedge, Sigurd Lenzen, Yasser H.A. Abdel‐Wahab, Lamin Marenah, D. F. Orr, Cassidy Lia Shaw, Peter R. Flatt, Kamal Chokkalingam, P. I. Mansell, Per Axel Clausen, Pia Ekbom, Peter Damm, Ulla Feldt‐Rasmussen, Britt A. Nielsen, Elisabeth R. Mathiesen, Bo Feldt‐Rasmussen, Shivani Dewan, Nicole Da Silva, P. Mc Ternan, K Leong, John Wilding, Natalia Asatiani, Ramaz Kurashvili, M. Dundua, Elena Shelestova, K I Pagava, M. Ramazashvili, Moshe Hod, Sergey Smirnov, J.L. Petersen, T. Justesen, Lene Ringholm, Christian Müller, K. Højlund, Andreas J. Wensaas, Elizabeth Kase, Vigdis Aas, A. C. Rustan, G. Hege Thoresen, Klaus Levin, Henning Beck‐Nielsen, Michael Gaster, Suyeol Im, Sung‐Yoon Kang, Saintpee Kim, Yong‐Ho Ahn, A. S. Lihn, Dieter Schmoll, Tim C. Werner, A. Kienitz, M. Renée Umstattd Meyer, A. Barthel, F. Ailett, Calum Sutherland, Rodolfo Álvarez-Sala Walther, Rolf Grempler, Shlomo Sasson, Rudolf H. Reich, Tobias Tenenbaum, Ellen Alpert, Giovanni Anfossi, Isabella Russo, M. Traversa, Paola Massucco, Luigi Mattiello, Gabriella Doronzo, Mariella Trovati, Sean Lally, Chenxin Tan, D. Owens, G. H. Tomkin, Isabelle Porchay, Franck Péan, N. Bellili, D. Betoulle, Beverley Balkau, J. Tichet, M. Marre, F. Fumeron, G. Chatellier, F. Alhenc-Gelas, Gregory A. Nichols, Judith Brown, Risa P. Hayes, Lyndsey J. Bowman, Heinz Drexel, C.H. Saely, Thomas Marte, Werner Benzer, P. Langer, Guenter Hoefle, Willi Moll, Stefan Aczél, Efstratios Karagiannis, G Lübben, Robin Urquhart, G. Edwards, S. Bruce, H. S. C. Howlett, N. Cugnardey, K. C. Turner, J.-S. Park, F. T. Fiedorek, Angelo Avogaro, A. Gallo, Piergiacomo Calzavara‐Pinton, R Rizzuto, Emily Murphy, G. Ceolotto, I D Caterson, B Guy-Grand, Jai Hill, M. Barone, Antonella Aiello, G. Allochis, Vito Borzı̀, Francesca Cannata, S Caronna, Antonio d'Avanzo, R. Elli, Gloria Formoso, Augusto F. Paroli, R. Scardapane, Pierluigi Sorichetti, Patrizio Tatti, Giorgio Luciano Viviani, Fausto Santeusanio, Daniela Manzella, Roberto Grella, Angela Marie Abbatecola, Giuseppe Paolisso, L. G. Søndergaard, T.B.M. Monster, Søren Paaske Johnsen, Maria Olsen, J. K. McLaughlin, Henrik Toft Sørensen, H. H. Lervang, Jørgen Rungby, V. Lyssenko, Jonas Fredriksson, Peter Almgren, Dragi Anevski, Marju Orho‐Melander, Moa Sjögren, Jaakko Tuomilehto, Leif Groop, Riphed Jaziri, R. Aubert, J. Tuomilehto, Geng Dong Hu, Pekka Jousilahti, Markku Peltonen, Jaana Lindström, Ageliki Laina, Maria Alevizaki, George Philippou, A. Souvatzoglou, E. Anastasiou, Samie Reyes de Alba, Bradley S. Metcalf, L D Voss, Alison Jeffery, Terence J. Wilkin, C. Glüimer, Stephen Colagiuri, Dorte Vistisen, K. Borch‐Johnsen, Aveni Haynes, Carol Bower, Max Bulsara, T.W. Jones, Elizabeth A. Davis, Henrik B. Mortensen, Philip Hougaard, Reinhard W. Holl, Peter Swift, Flemming Pociot, Mikael Knip, Leif Hansen, Agnieszka Szadkowska, Iwona Pietrzak, Agnieszka Zmysłowska, Krystyna Wyka, Jerzy Bodalski, Reinhard W. Holl, Robin Swift, Rikke Frøhlich Hougaard, EM Gerstl, I Engelsberger, Wolfgang Rabl, Joachim Rosenbauer, H Gröbe, Sabine E. Hofer, U. Krause, D. Dabelea, T. Morgan, D. J. Pettitt, Lawrence M. Dolan, Elizabeth J. Mayer‐Davis, C. Pihoker, Teresa A. Hillier, G. Imperatore, Andrea Ruggiero, R. E. Hamman, Andreas Stylianou, N. Tentolouris, Δέσποινα Περρέα, Alexandros D. Tselepis, E. Lourida, E. Kitsou, Nikolaos Katsilambros, Monica Vedovato, A. R. Dodesini, Gianluca Lepore, Antonio Tiengo, R. Trevisan, Giuseppe Penno, Roberto Miccoli, Laura Pucci, Daniela Lucchesi, S. Bandinelli, Carmen Fotino, S. Triscornia, E. Baldassari, S. Del Prato, Gianpaolo Reboldi, Egidio Santeusanio, J.H. Fuller, Robyn G. Langham, Renae M. Gow, Y. Zhang, Dominique Kelly, Per K. Christensen, H.-H. Parving, R Gilbert, Alexander Chibalin, Zhao Zhong, О. С. Котова, A. Davidescu, Ira Ehren, K. Ekberg, J. Wahren,
Springer Science+Business Media
Walid Habre, Nicola Disma, Katalin Virág, Karin Becke, Tom G. Hansen, Martin Jöhr, Brigitte Leva, N S Morton, P. M. Vermeulen, Marzena Zielińska, Krisztina Boda, Francis Veyckemans, Walter Klimscha, Regina Konecny, Robert Luntzer, Ulrike Morawk-Wintersperger, F. X. Neiger, Lydia Rustemeyer, Christian Breschan, D FREY, M. Platzer, Reinhard Germann, Joachim Oeding, Birgit Stoegermüller, Bernhard Ziegler, Philipp Brotatsch, A. Gutmann, G. Mausser, Brigitte Messerer, Wolfgang Toller, Maria Vittinghoff, Gregor Zangl, Natascha Seidel-Ahyai, Christoph Hochhold, Ruth Kroess, Peter Paal, Steven Cnudde, Patricia Coucke, Birgit Loveniers, John Mitchell, D. Ethan Kahn, Thierry Pirotte, Caroline Prégardien, Francis Veyckemans, Marc Coppens, Stefan De Hert, Björn Heyse, Martine Neckebroek, Aliaksandra Parashchanka, Jurgen Van Limmen, Nancy Van Den Eynde, Caroline Vanpeteghem, Piet Wyffels, M. Lalot, Jean-Paul Lechat, France Stevens, Sari Casaer, F. De Groote, Françoise De Pooter, A. De Villé, M. Gerin, Natalia Magasich, Cristel Sanchez Torres, Denise Van Deenen, J. Berghmans, D. Himpe, Eva Roofthooft, Ellen Joukes, Carine Smitz, V. Van Reeth, Christel Huygens, Julie Lauweryns, Karen De Smet, Nadia Najafi, Jan Poelaert, Anne Van de Velde, Veerle Van Mossevelde, Ivan Bekavac, Diana Butković, Dubravka Heli Litvic, Ivana Kerovec Sorić, Hrvoje Maretic, Djurdjica Moscatello, Ljiljana Popović, Slobodan Micici, Ivana Stuck Tus, Lada Kalagac Fabris, Tatjana Šimurina, Nina Sulen, Gordana Kesic-Valpotic, Dajana Djapić, Jiří Žůrek, Lucie Jureckova, Iveta Mackova, Monika Skacel, Stanislava Weinlichova, Jan Divák, Michal Frelich, René Urbanec, Vera Biskupova, Vladimír Mixa, Jana Pavlíčková, Arash Afshari, Morten Bøttger, Marguerite Ellekvist, Mathias Johansen, Birgitte Ingeborg Madsen, Jens Christian Nilsson, Birgitte Schousboe, Nicola G. Clausen, Tom G. Hansen, Nick Phaff Steen, Mari‐Liis Ilmoja, Virge Tonise, Juri Karjagin, Reet Kikas, Mika H. Isohanni, Annina Lyly, A. Takala, Johanna Happo, Kai Kiviluoma, Kati Martikainen, Riku Aantaa, Tuula Manner, Sanna Vilo, Catherine Amory, Hugues Ludot, Patricia Lambotte, René Busche, Olivier Jacqmarcq, C. Lejus, J. Corouge, Christian Erb, Delphine Garrigue, Patricia Gillet, Anne Laffargue, Veronique Lambelin, Hélène Le Freche, Daliana Peres-Bota, P. Richart, Jérôme Berton, C. Chapotte, L. Colbus, T. Lehousse, J.P. Monrigal, Catherine Baujard, P Roulleau, Giuseppe Staiti, H. Batoz, M. Bordes, Anne Didier, Yann Hamonic, Sylvaine Lagarde, Karine Nouette‐Gaulain, F. Semjen, B. Zaghet, Jacky Dekens, Axelle Delcuze, Hervé Dupont, Aurélien Legrand, Celine Raffoflandreur, Noémie Audren, Blandine Camus, M. Cartal, Chantal Chazelet, Isabelle Davin, Marion Guillier, L. Desjeux, Claire Larcher, Elodie Grein, Mickeal Leclercq, Roxana Levitchi, Lilica Rosu, Dominique Simon, Aurélien Zang, Anne Migeon, Anne-Charlotte Gagey, Nathalie Bourdaud, Anne-Charlotte Carre, Frédéric Duflo, J. A. Riche, Philippe Robert, Emilie Druot, O. Maupain, Gilles Orliaguet, Lucie Sabau, H. Taright, Lynn Uhrig, Juliette Verchere-Montmayeur, Lise Dorchin Debrabant, Clotaire Pilla, Alexandre Podvin, Benjamin Roth, Souhayl Dahmani, Florence Julien‐Marsollier, Nada Sabourdin, Bogdan Alexandri, Gilles Brezac, François de la Brière, C Hayem, Elizabeth Lhubat, J. P. Mission, Charlotte Rémond, Christophe Dadure, Maud Maniora, Anaïs Marie, Philippe Pirat, Anne-Charlotte Saour, Chrystelle Sola, Claude Ecoffey, Éric Wodey, Christian Adam, Thomas Standl, Ehrenfried Schindler, Tomohiro Yamamoto, Michael Brackhahn, Christoph Eich, Holger Guericke, P. KINDERMANN, Michael Laschat, Cornel Schink, Frank Wappler, Claudia Hoehne, Natalia Skordou, Johanna Ulrici, Martin Jetzek-Zader, Peter Kienbaum, Tanja Meyer‐Treschan, O. Picker, Maximilian S. Schaefer, Golo Mielke, Sabine Baethge, Axel Ramminger, Martin Bauer, Matthias Bollinger, José Hinz, Michael Quintel, Sebastian G. Russo, Michael Bauer, D. Geil, Andreas Kortgen, Niels-Peter Preussler, Ulrich Hofmann, M. Raber, Doris Reindl, Karin Becke, Karin Oppenrieder, Bettina Schierlinger, Jens Roth, Wolfgang Funk, Thomas Fischer, C. Gernoth, Christina Wiefelspütz, Hauke Volger, Nicole Zederer, Anja Diers, Matthias Huber, Clemens Schorer, A. Weyland, Konrad Schwarzkopf, Catharina Grau, Winfried Roth, Rolf Holy, Thomas H. Mader, Laura Peter, Hauke Supthut, Thomas Kuehhirt, A. S. Milde, Fritz Fiedler, C. Isselhorst, U. Grundmann, Alexander Pattar, Jennifer Reinert, Birgit Ehm, Katrin Fritzsche, Ralf Gaebler, Patrick Meybohm, Maximilian Hein, Ines Guzman, Johanna Jokinen, Peter Kranke, Ulrich Goebel, Sarah Harris, Christoph Eisner, Miriam Ochsenreiter, Michael Schoeler, E. Thil, Richard K. Ellerkmann, Andreas Hoeft, Claudia Neumann, Stefan Weber, Julia Keilhauer, Jan Kloessing, Michael P. Schramm, Uwe Trieschmann, Kristina Knauss,
Background Little is known about the incidence of severe critical events in children undergoing general anaesthesia in Europe. We aimed to identify the incidence, nature, and outcome of severe critical events in children undergoing anaesthesia, and the associated potential risk factors. Methods The APRICOT study was a prospective observational multicentre cohort study of children from birth to 15 years of age undergoing elective or urgent anaesthesia for diagnostic or surgical procedures. Children ...
Elsevier BV
Produção Nacional
Revisado por pares
Mariana Mara Buen, Eliana Amaral, Renato T. Souza, Renato Passini, Giuliane Jesus Lajos, Ricardo Porto Tedesco, Marcelo Luís Nomura, Tábata Z. Dias, Patrícia Moretti Rehder, Maria Helena de Sousa, José Guilherme Cecatti, Sérgio Tadeu Martins Marba, Jacinta P. Matias, Nelson Lourenço Maia Filho, Vera Therezinha Medeiros Borges, Laércio R. Oliveira, Tenílson Amaral Oliveira, Augusta M. B. Assumpção, Maria Elizabeth Lopes Moreira, Marcela A. F. Guedes, Cintia E. Senger, Janete Vettorazzi, Francisco Eulógio Martinez, Silvana Maria Quintana, Patrícia P. S. Melli, Antonio C. F. Barbosa Lima, Débora F. Leite, Elias F. Melo, Dênis José Nascimento, Edson Gomes Tristão, Luciana F. Siqueira, Pedro R. Coutinho, Ruth Guinsburg, Ana Cristina Perez Zamarian, Eduardo de Souza, Marília G. Martins, Marynea V. Nunes, Cláudio Sérgio Medeiros Paiva, Djacyr Magna Cabral Freire, Moisés Diôgo de Lima, Ana Maria Feitosa Porto, Isabela Cristina Coutinho de Albuquerque Neiva Coêlho, Adriana Suely Oliveira Melo, Fabiana O. Melo, Melânia Maria Ramos Amorim, Carlos A. S. Menezes, Marcelo de Amorim Aquino, Francisco Edson Lucena Feitosa, George N. Chaves, M.R.F. Silveira, Nelson Sass, Fátima Aparecida Henrique Lotufo, Kaliane P. Uzilin, Carla Betina Andreucci, Elvira A. O. Zanette,
Abstract Spontaneous preterm birth (sPTB) is a major pregnancy complication involving biological, social, behavioural and environmental mechanisms. Workload, shift and intensity may play a role in the occurrence of sPTB. This analysis is aimed addressing the effect of occupational activities on the risk for sPTB and the related outcomes. We conducted a secondary analysis of the EMIP study, a Brazilian multicentre cross-sectional study. For this analysis, we included 1,280 singleton sPTB and 1,136 ...
Tópico(s): Maternal and Perinatal Health Interventions
2020 - Nature Portfolio | Scientific Reports
Dmitri Nepogodiev, Aneel Bhangu, James Glasbey, Elizabeth Li, Omar Omar, Joana F F Simoes, Tom Abbott, Osaid Alser, Alexis Arnaud, Brittany Bankhead-Kendall, Kerry Breen, Miguel F Cunha, Giana H. Davidson, Salomone Di Saverio, Gaetano Gallo, Ewen A. Griffiths, Rohan R Gujjuri, Peter Hutchinson, Haytham M.A. Kaafarani, Hans Lederhuber, Markus Löffler, Hassan Mashbari, Ana Minaya‐Bravo, Dion Morton, David Moszkowicz, Francesco Pata, George Tsoulfas, Mary L Venn, Daniel Cox, April Camilla Roslani, Felix Alakaloko, J.P. de Vries, Mahmoud Al Aaraj, Tom Abbott, Tom Abbott, Mutwakil OM Abdalla, Ahmed Samir Abdelaal, Adesoji Ademuyiwa, Thomas Aherne, Osman Ali, Ghadah Z Alkadeeki, Ana C. Almeida, Mahmoud Maher Abdelnaby Alrahawy, Graeme K. Ambler, Ehab Alameer, Stefano Andreani, Beatriz De Andrés-Asenjo, L López Antoñanzas, Salah G. Aoun, F Ashoush, Knut Magne Augestad, R Avellana, Funbi Ayeni, J Ayorinde, B H Babu, M. Baig, O Bajomo, Omer Baker, Markus Baker, Alexander J. Baldwin, Vin Shen Ban, Ryan Baron, Alberto G. Barranquero, Conor Barry, A Di bartolomeo, Gary Alan Bass, Michael Bath, H. Hunt Batjer, Andrew J. Beamish, Ajay Belgaumkar, Matthew N Bence, Ruth Benson, Juan Carlos Bernal-Sprekelsen, Anuradha R. Bhama, Avi Bhavaraju, Walter L. Biffl, Chris Blundell, Alex Boddy, Alexander B.J. Borgstein, David C. Bosanquet, Karen Bosch, Ahmad Bouhuwaish, Mehmet Abdussamet Bozkurt, Collin EM Brathwaite, Benjamin Brown, Oliver Brown, A Brown, Igor Lima Buarque, A.D. Bueno Cañones, Mustafa R Bulugma, Josh Burke, Matthew H V Byrne, Elima P Cagigal-Ortega, Rachael A. Callcut, Francesca Di Candido, M Canova, William Carlos, Edward Caruana, Liam D. Cato, Andrew B Catton, Andrea Pisani Ceretti, T Chase, Francesco Chiara, Abeed H. Chowdhury, Eric A Chung, Pierfranco Maria Cicerchia, Ethan C.S. Clough, Natasha Coleman, Chris Collins, Michelle Collins, Emily Colonna, Lara Valentina Comini, Patrick A. Coughlin, Laura Fernández-Gomez Cruzado, Brian R Davidson, Richard Davies, Emma Jane Davies, Niall F. Davis, Brett E Dawson, Benjamin Dean, Maria Garcia-Conde Delgado, José J. Diaz, Kathryn E Dickson, Manuel Díez‐Alonso, Ján Dixon, Matthew Doe, Thomas D Drake, Frederick Thurston Drake, John P. Duffy, Declan F.J. Dunne, Naomi JM Dunne, Virginia María Durán-Muñoz-Cruzado, Alexander Durst, N Eardley, John Edwards, Ahmed Hossam Elfallal, Mahmoud Elfiky, Jessie A. Elliott, Sameh Hany Emile, K Emslie, Frederick W Endorf, Jamie L. Engel, Diego Tristán Enjuto Martínez, Eric Etchill, Jonathan P Evans, Brian A Fahey, Carlos Faria, Carlo V. Feo, Henry J.M. Ferguson, Beatriz Dieguez Fernandez, Andres Garcia Fernandez, Antonio J Fernández, Borja Camacho Fernández-Pacheco, J.E.F. Fitzgerald, Giovanni Battista Fonsi, Roser Font, Amy Fowler, Kenneth R. Fretwell, Lorena Sanchon Fructuoso, Giuseppe Fusai, M Hernández-García, Miguel Ángel García Ureña, C Gill, Suzanne S. Gisbertz, Roberto Del Giudice, Maria Carmela Giuffrida, Matteo Di Giuseppe, María Fanjul Gómez, Ewen A. Griffiths, C A Guariglia, Alison Hainsworth, Bria J. Hall, James RW Hall, John Hammond, Maha H. Haqqani, Ewen M. Harrison, Joshua P. Hazelton, Maarten van Heinsbergen, Arnold D. Hill, Caroline Hing, Sameer Hirji, Michael Ho, Charlotte Holbrook, Thomas Holme, James Hopkins, David Hopkinson, Fahad Hossain, Victoria Hudson, Jane L Hughes, Eui-Hyoung Hwang, Mohamed Ibrahim, S M Isolani, Michael D. Jenkinson, Hillary E. Jenny, Deva S. Jeyaretna, Robert Jones, Andy Jones, Pascal Jonker, Maria L Jönsson, Doireann Joyce, Kyle J. Kalkwarf, Sivesh K. Kamarajah, Mohamed El‐Kassas, Dara O. Kavanagh, James M Keatley, Mohamed A Khalefa, Jim Khan, Bilal H. Kirmani, A Kisiel, S. Kouris, Mikolaj Kowal, Peter Labib, John O. Larkin, Johannes C. Lauscher, Wouter K. G. Leclercq, Frances SJ Ledesma, André M. Leite-Moreira, Elaine Leung, Sophia E Lewis, Maria João Lima, Daniel J. Lin, Helen H. Liu, Aoïfe Lowery, Saida Martel Lozano, C Luney, Mariana Magalhães Maia, Nicolò Maria Mariani, Marco V. Marino, Angelo Alessandro Marra, Christopher L. Marsh, Robert C.G. Martin, Simon McCluney, Robert C. McIntyre, Siobhan C. McKay, Kevin McKevitt, Ashley D. Meagher, Mohammad Q Mehdi, Brian Mehigan, Melania Gonzalez-De Miguel, Maria-Carmen De Miguel-Ardevines, Sarah Mills, Helen Mohan, John Moir, John RT Monson, Joana M Monteiro, Maria Teresa Montella, C Soto Montesinos, Marwa Morgom, Francisco Serra E Moura, J.M. Mugüerza, Suzanne Murphy, Paola De Nardi, David N Naumann, Paul Neary, David TA Neely, Joshua S Ng-Kamstra, Albert WT Ngu, Truong An Nguyen, G E Nita, Quentin Nunes, Rachel M. Nygaard, Lindsay O’Meara, John O’Neill, Barbara U. Okafor, Steven A. Olson, Aung Oo, Pablo Collera Ormazabal, Alexander Osorio, Max Pachl, James T Parry, Panna Patel, Luis Eduardo Pérez‐Sánchez, Ana Nogués Pevidal, A P Pezzuto, Matthew M. Philp, Thomas Pinkney, Joerg M. Pollok, Meical Povey, Alfredo Alonso Poza, Amarkumar Dhirajlal Rajgor, Jagan Rao, Dimitri Aristotle Raptis, Henry E. Rice, Paul F. Ridgway, Ana Munoz Rivas, Juan Carlos Rodríguez-Sanjuán, Luke Rogers, Anna Da Roit, Rebecca Rollett, José L. Romera, Siobhán Rooney, V Roxo, Bertrand Le Roy, Eduardo E Rubio, Carolina Castro Ruiz, Manuel Losada Ruiz,
Summary Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within ...
Elsevier BV
Frances R. Balkwill, Melania Capasso, Thorsten Hagemann,
... range of malignant cells, including cancer stem cells (Gomes et al., 2010; Hannani et al., 2012). Although ...
Tópico(s): Nanoplatforms for cancer theranostics
2012 - The Company of Biologists | Journal of Cell Science
Athanasios Kousathanas, Erola Pairo‐Castineira, Konrad Rawlik, A. Stuckey, Christopher A. Odhams, Susan Walker, Clark D Russell, Tomas Malinauskas, Yang Wu, Jonathan Millar, Xia Shen, Katherine S. Elliott, Fiona Griffiths, Wilna Oosthuyzen, Kirstie Morrice, Seán Keating, Bo Wang, Daniel R. Rhodes, Lucija Klarić, Marie Zechner, Nick Parkinson, Afshan Siddiq, Peter Goddard, Sally Donovan, David M. Maslove, Alistair Nichol, Malcolm G. Semple, Tala Zainy, F. Maleady-Crowe, Linda Todd, Shahla Salehi, Julian C. Knight, Greg Elgar, G. C. Chan, Prabhu Arumugam, Christine Patch, Augusto Rendon, David Bentley, Clare Kingsley, Jack A. Kosmicki, Julie Horowitz, Aris Baras, Gonçalo R. Abecasis, Manuel A. R. Ferreira, Anne E. Justice, Tooraj Mirshahi, Matthew T. Oetjens, Daniel J. Rader, Marylyn D. Ritchie, Anurag Verma, Tom Fowler, Manu Shankar‐Hari, Charlotte Summers, Charles Hinds, Peter Horby, Lowell Ling, Daniel F. McAuley, Hugh Montgomery, Peter Openshaw, Paul Elliott, Timothy Walsh, Albert Tenesa, J. Kenneth Baillie, Colin B. Begg, Sara Clohisey, Charles Hinds, Peter Horby, Julian C. Knight, Lowell Ling, David M. Maslove, Daniel F. McAuley, Johnny Millar, Hugh Montgomery, Alistair Nichol, Peter Openshaw, Alexandre C. Pereira, Chris P. Ponting, Kathy Rowan, Malcolm G. Semple, Manu Shankar‐Hari, Charlotte Summers, Timothy Walsh, Latha Aravindan, Ruth Armstrong, Heather Biggs, Ceilia Boz, Adam Brown, Richard E. Clark, Audrey Coutts, J. Terrence Coyle, Louise Cullum, Sukamal Das, Nicky Day, Lorna Donnelly, Esther Duncan, Angie Fawkes, Paul Finernan, Max Head Fourman, Anita Furlong, James Furniss, Bernadette Gallagher, Tammy Gilchrist, Ailsa Golightly, Fiona Griffiths, Katarzyna Hafezi, Debbie Hamilton, Ross Hendry, Andy Law, Dawn Law, R. M. Law, Sarah Law, Rebecca Lidstone-Scott, Louise MacGillivray, Alan Maclean, Hanning Mal, Sarah McCafferty, Ellie Mcmaster, Jen Meikle, Shona C. Moore, Kirstie Morrice, Lee Murphy, Sheena Murphy, Mybaya Hellen, Wilna Oosthuyzen, Chenqing Zheng, Jiantao Chen, Nick Parkinson, Trevor Paterson, Katherine Schon, Andrew Stenhouse, Mihaela Das, Maaike Swets, Helen Szoor-McElhinney, Filip Taneski, Lance Turtle, Tony Wackett, Mairi Ward, Jane Weaver, Nicola Wrobel, Marie Zechner, Gill Arbane, Aneta Bociek, Sara Campos, Neus Grau, Tim Jones, Rosario Lim, Martina Marotti, Marlies Ostermann, Manu Shankar‐Hari, R. Chris Whitton, Zoe Alldis, Raine Astin-Chamberlain, Fatima Bibi, Jack Biddle, Sarah Blow, Matthew L. Bolton, Catherine Borra, Ruth Bowles, Maudrian Burton, Yasmin Choudhury, David Collier, Amber Cox, Amy Easthope, Patrizia Ebano, Stavros Fotiadis, Jana Gurasashvili, Rosslyn Halls, Pippa Hartridge, Delordson Kallon, Jamila Kassam, Ivone Lancoma-Malcolm, Maninderpal Matharu, P. May, Oliver Mitchelmore, Tabitha Newman, Mital Patel, Jane Pheby, Irene Pinzuti, Zoe Prime, Oleksandra Prysyazhna, Julian Shiel, Melanie Taylor, Carey Tierney, S. M. Wood, Anne Zak, Olivier Zongo, Stephen Bonner, Keith Hugill, Jessica Jones, Steven Liggett, Evie Headlam, Nageswar Bandla, Minnie Gellamucho, Michelle Davies, C. C. Thompson, Marwa Abdelrazik, Dhanalakshmi Bakthavatsalam, Munzir Elhassan, Arunkumar Ganesan, Anne Haldeos, Jerónimo Moreno-Cuesta, Dharam Purohit, Rachel Vincent, Kugan Xavier, Rohit Kumar, Alasdair Frater, Malik Saleem, Emma Carter, Samuel Jenkins, Zoe Lamond, Alanna Wall, Jaime Fernandez-Roman, David Hamilton, Emily Johnson, Brian Johnston, Maria Lopez Martinez, Suleman Mulla, David Shaw, Alicia Waite, Victoria Waugh, Ingeborg Welters, Karen Williams, Anna Cavazza, Maeve Cockrell, Eleanor Corcoran, Maria Depante, Clare Finney, Ellen Jerome, Mark McPhail, Monalisa Nayak, Harriet Noble, Kevin O’Reilly, Evita Pappa, Rohit Saha, Sian Saha, John Smith, Abigail Knighton, David Antcliffe, Dorota Banach, Stephen J. Brett, Phoebe Coghlan, Ziortza Fernandez, Anthony Gordon, Roceld Rojo, Sonia Sousa Arias, Maie Templeton, Megan Meredith, Lucy Morris, Lucy Ryan, Amy Clark, Julia Sampson, Cecilia Peters, Martin Dent, Margaret Langley, Saima Ashraf, Shuying Wei, Angela Andrew, Archana Bashyal, Neil Davidson, Paula Hutton, Stuart McKechnie, Jean Wilson, David Baptista, Rebecca Crowe, Rita Fernandes, Rosaleen Herdman-Grant, Anna Joseph, Denise O’Connor, Meryem Allen, Adam Loveridge, India McKenley, Eriko Morino, Andrés Naranjo, Richard Simms, Kathryn Sollesta, Andrew Swain, Harish Venkatesh, Jacyntha Khera, Jonathan Fox, Gillian Andrew, J. Kenneth Baillie, Lucy Barclay, Marie Callaghan, Rachael Campbell, Sarah J. Clark, Dave Hope, Lucy Marshall, Corrienne McCulloch, Kate Briton, Jo Singleton, Sophie Birch, Lutece Brimfield, Zoe Daly, David Pogson, Steve Rose, Angela Nown,
Abstract Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care 1 or hospitalization 2–4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals ...
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The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed ...
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