Rebecca K. Sripada, P. Pfeiffer, Jessica Rampton, Dara Ganoczy, Sheila A. M. Rauch, Melissa A. Polusny, Kipling M. Bohnert,
Although the U.S. Department of Veterans Affairs (VA) has prioritized care for posttraumatic stress disorder (PTSD), many patients with PTSD remain symptomatic. Patterns of PTSD symptom change are not well understood. Thus, the current study was designed to categorize and investigate potential predictors of symptom trajectories in patients with PTSD. The sample comprised 2,237 VA patients who were diagnosed with PTSD in 2013 and completed at least 4 PTSD Checklist (PCL) assessments over 12 weeks. Latent ...
Tópico(s): Migration, Health and Trauma
2017 - Wiley | Journal of Traumatic Stress
Andrea Gläßel, Alexandra Rauch, Melissa Selb, Karl Emmenegger, Miriam Lückenkemper, Reuben Escorpizo,
Vocational rehabilitation (VR) plays a key role in bringing persons with acquired disabilities back to work, while encouraging employment participation. The purpose of this case study is to illustrate the systematic application of International Classification of Functioning, Disability, and Health (ICF)-based documentation tools by using ICF Core Sets in VR shown with a case example of a client with traumatic spinal cord injury (SCI).The client was a 26-year-old male with paraplegia (7th thoracic level), ...
Tópico(s): Spinal Cord Injury Research
2012 - IOS Press | Work
... 006-9016-yMaria Elizabeth Grabe, K. D. Trager, Melissa Lear, Jennifer Rauch Gender in Crime News: A Case Study Test ...
Tópico(s): Criminal Justice and Corrections Analysis
1986 - University of Chicago Press | Signs
... 1093/bjc/azl014Maria Elizabeth Grabe, K. D. Trager, Melissa Lear, Jennifer Rauch Gender in Crime News: A Case Study Test ...
Tópico(s): Criminal Law and Policy
1918 - University of Chicago Press | American Journal of Sociology
K Ernst, Daniel A. Rauch, Vanessa Hill, Melissa Mauro-Small, Benson Hsu, Vinh Thuy Lam, Charles D. Vinocur, Jennifer A. Jewell,
It is crucial that all children are provided with high-quality and safe health care. Pediatric inpatient needs are unique in regard to policies, equipment, facilities, and personnel. The intent of this clinical report is to provide recommendations for the resources necessary to provide high-quality and safe pediatric inpatient medical care.
Tópico(s): Child and Adolescent Health
2020 - American Academy of Pediatrics | PEDIATRICS
Matthew S. Ning, Aradhana M. Venkatesan, R. Jason Stafford, Thao P. Bui, Richard Carlson, Neil Bailard, Sastry Vedam, Rasheda Davis, Nicholas D. Olivieri, Alexis B. Guzman, James R. Incalcaterra, Florence A. McKelvey, Nikhil G. Thaker, Gaiane M. Rauch, Chad Tang, Steven J. Frank, Melissa Joyner, Lilie L. Lin, Anuja Jhingran, Patricia J. Eifel, Ann H. Klopp,
We integrated a brachytherapy procedural workflow within an existing diagnostic 3.0-T (3T) MRI suite. This setup facilitates intraoperative MRI guidance for optimal applicator positioning, particularly for interstitial needle placements in gynecologic cases with extensive parametrial involvement.Here we summarize the multidisciplinary collaboration, equipment, and supplies necessary to implement an intraoperative MRI-guided brachytherapy program; outline the operational workflow via process maps; ...
Tópico(s): Management of metastatic bone disease
2019 - Elsevier BV | Brachytherapy
Maria Elizabeth Grabe, K. D. Trager, Melissa Lear, Jennifer Rauch,
Abstract This content analysis tested the chivalry hypothesis in 6 months of crime reporting in a local U.S. newspaper. The chivalry hypothesis posits that female criminals receive more lenient treatment in the criminal justice system and in news coverage of their crimes than their male counterparts. The study found partial support for the chivalry hypothesis and prompts a more nuanced formulation of the hypothesis-here termed patriarchal chivalry. This study also produced evidence that news coverage ...
Tópico(s): Media Studies and Communication
2006 - Taylor & Francis | Mass Communication & Society
Ralf Lenigk, Robin H. Liu, M. M. Athavale, Zhijian Chen, Dale Ganser, Jianing Yang, Cory B. Rauch, Yingjie Liu, Betty Chan, Huinan Yu, Melissa Ray, R Marrero, Piotr Grodzinski,
Conventional DNA hybridization assay kinetics depends solely on the diffusion of target to surface-bound probes, causing long hybridization times. In this study, we examined the possibilities of accelerating the hybridization process by using microfluidic channels ("biochannels") made of polycarbonate, optionally with an integrated pump. We produced two different devices to study these effects: first, hybridization kinetics was investigated by using an eSensor electrochemical DNA detection platform ...
Tópico(s): Microfluidic and Bio-sensing Technologies
2002 - Elsevier BV | Analytical Biochemistry
Cora C. Breuner, Elizabeth M. Alderman, Jennifer A. Jewell, Elise D. Berlan, Richard J. Chung, Michael Colburn, Laura K. Grubb, Janet Lee, Stephenie Wallace, Makia E. Powers, Krishna K. Upadhya, Anne-Marie Amies, Liwei L. Hua, Ellie Vyver, Seema Menon, Lauren B. Zapata, Maria H. Rahmandar, Karen Smith, James Baumberger, Daniel A. Rauch, Samantha A. House, Benson Hsu, Melissa Mauro-Small, Nerian Ortiz-Mato, Charles Vinocur, Nicole Webb, Kimberly Ernst, Vinh Lam, Michael S. Leonard, Karen Castleberry, Nancy D. Hanson, Kristin Hittle Gigli, Barbara Romito, S. Niccole Alexander,
This clinical report provides pediatricians evidence-based information on the developmentally appropriate, comprehensive clinical care for hospitalized adolescents. Included in this report are opportunities and challenges facing pediatricians when caring for specific hospitalized adolescent populations. The companion policy statement, “The Hospitalized Adolescent,” includes detailed descriptions of adolescent hospital admission demographics, personnel recommendations, and hospital setting and design ...
Tópico(s): Child and Adolescent Health
2023 - American Academy of Pediatrics | PEDIATRICS
S Rauch, Kathy H. Huen, Miles C. Miller, Hira Chaudry, Melissa Lau, Joshua R. Sanes, Conrad E. Johanson, Edward G. Stopa, Robert W. Burgess,
Conditions that compromise the blood-brain barrier (BBB) have been increasingly implicated in the pathogenesis of Alzheimer disease (AD). AGRIN is a heparan sulfate proteoglycan found abundantly in basement membranes of the cerebral vasculature, where it has been proposed to serve a functional role in the BBB. Furthermore, AGRIN is the major heparan sulfate proteoglycan associated with amyloid plaques in AD brains. To examine the relationship of AGRIN, the BBB, and AD-related pathologies, we generated ...
Tópico(s): Intracerebral and Subarachnoid Hemorrhage Research
2011 - Oxford University Press | Journal of Neuropathology & Experimental Neurology
William D. S. Killgore, Zachary J. Schwab, Mareen Weber, Maia Kipman, Sophie R. DelDonno, Melissa R. Weiner, Scott L. Rauch,
The recent epidemic of obesity corresponds closely with the decline in the average number of hours of sleep obtained nightly. While growing research suggests that sleep loss may affect hormonal and other physiological systems related to food intake, no studies have yet explored the role that sleepiness may play in reducing prefrontal inhibitory control over food intake. Because evidence suggests that women may be more prone to obesity and eating disorders, as well as more likely to suffer from sleep ...
Tópico(s): Eating Disorders and Behaviors
2013 - Elsevier BV | NeuroImage
William D. S. Killgore, Mareen Weber, Zachary J. Schwab, Sophie R. DelDonno, Maia Kipman, Melissa R. Weiner, Scott L. Rauch,
Research suggests that emotional intelligence capacities may be related to the functional integrity of the corticolimbic regions including the ventromedial prefrontal cortex, insula, and amygdala. No study has yet examined regional brain volumes in relation to the two dominant models of emotional intelligence: the Ability model, which posits a set of specific demonstrable capabilities for solving emotional problems, and the Trait model, which proposes a set of stable emotional competencies that ...
Tópico(s): Neural and Behavioral Psychology Studies
2012 - Lippincott Williams & Wilkins | Neuroreport
Kevin Roy, Melissa Rauch, Fernando Stein, Eric A. Williams, Kimia Rafie, Vincent Gagné, Emma Fauss,
Roy, Kevin; Rauch, Melissa; Stein, Fernando; Williams, Eric; Rafie, Kimia; Gagne, Vincent; Fauss, Emma
Tópico(s): Sepsis Diagnosis and Treatment
2016 - Lippincott Williams & Wilkins | Critical Care Medicine
K. Maskos, C. Fernandez-Catalan, Robert Huber, Gleb Bourenkov, H.D. Bartunik, George A. Ellestad, P. Linga Reddy, Martin F. Wolfson, Charles T. Rauch, Beverly J. Castner, Raymond Davis, Howard R. G. Clarke, Melissa Petersen, Jeffrey N. Fitzner, Douglas Pat Cerretti, Carl J. March, Raymond J. Paxton, Roy A. Black, Wolfram Bode,
Tumor necrosis factor-α (TNFα) is a cytokine that induces protective inflammatory reactions and kills tumor cells but also causes severe damage when produced in excess, as in rheumatoid arthritis and septic shock. Soluble TNFα is released from its membrane-bound precursor by a membrane-anchored proteinase, recently identified as a multidomain metalloproteinase called TNFα-converting enzyme or TACE. We have cocrystallized the catalytic domain of TACE with a hydroxamic acid inhibitor and have solved ...
Tópico(s): Protease and Inhibitor Mechanisms
1998 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Isabelle M. Rosso, Melissa R. Weiner, David J. Crowley, Marisa M. Silveri, Scott L. Rauch, J. Eric Jensen,
Background Increased reactivity of the insular cortex and decreased activity of the dorsal anterior cingulate cortex (ACC) are seen in functional imaging studies of posttraumatic stress disorder (PTSD), and may partly explain the persistent fear and anxiety proneness that characterize the disorder. A possible neurochemical correlate is altered function of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). We report results from what we believe is the first study applying proton magnetic ...
Tópico(s): Traumatic Brain Injury Research
2013 - Wiley | Depression and Anxiety
Mareen Weber, William D. S. Killgore, Isabelle M. Rosso, Jennifer C. Britton, Zachary J. Schwab, Melissa R. Weiner, Naomi M. Simon, Mark H. Pollack, Scott L. Rauch,
Posttraumatic stress disorder (PTSD) is associated with functional abnormalities within a neurocircuitry that includes the hippocampus, amygdala, and medial prefrontal cortex. Evidence of structural abnormalities within these regions, and their association with PTSD severity and symptom burden is, however, sparse. The present study evaluated the relation between indices of gray matter volume and PTSD symptom severity using voxel-based morphometry. Fifteen individuals meeting DSM-IV criteria for PTSD ...
Tópico(s): Traumatic Brain Injury Research
2013 - Elsevier BV | Journal of Anxiety Disorders
Joellan Mullen, Sulimon Sattari, Melissa Rauch, Fernando Stein, Kevin Roy, Darlene E. Acorda,
Background: Nuisance and false alarms distract clinicians from urgent alerts, raising patient safety risks. Local Problem: High alarm rates in a pediatric progressive care unit resulted in experiencing 180-250 alarms per day or 1 alarm every 3 to 4 minutes per clinician. Methods: Through Plan-Do-Study-Act cycles, environmental, policy, and technology changes were implemented to decrease the average alarms/day/bed and percentage of time in alarm. Interventions: Alarm settings tailored to patient ...
Tópico(s): ECG Monitoring and Analysis
2024 - Lippincott Williams & Wilkins | Journal of Nursing Care Quality
David F. Tolin, Michael C. Stevens, Anna L. Villavicencio, Melissa M. Norberg, Vince D. Calhoun, Randy O. Frost, Gail Steketee, Scott L. Rauch, Godfrey D. Pearlson,
Hoarding disorder (HD), previously considered a subtype of obsessive-compulsive disorder (OCD), has been proposed as a unique diagnostic entity in DSM-5. Current models of HD emphasize problems of decision-making, attachment to possessions, and poor insight, whereas previous neuroimaging studies have suggested abnormalities in frontal brain regions.To examine the neural mechanisms of impaired decision making in HD in patients with well-defined primary HD compared with patients with OCD and healthy ...
Tópico(s): Autism Spectrum Disorder Research
2012 - American Medical Association | Archives of General Psychiatry
Harmeet Kaur, Helena Gabriel, Melissa W. Taggart, Hyunseon C. Kang, Tsuyoshi Konishi, Gaiane M. Rauch, Sunil Krishnan, George J. Chang,
The treatment of rectal cancer centers around the distinct but related goals of management of distant metastases and management of local disease. Optimal local management requires attention to the primary tumor and its anatomic relationship to surrounding pelvic structures, with the goal of minimizing local recurrence (LR). High-resolution MRI is ideally suited for this purpose; application of MRI-based criteria in conjunction with optimized surgical and pathologic techniques has successfully reduced ...
Tópico(s): Colorectal and Anal Carcinomas
2021 - American Roentgen Ray Society | American Journal of Roentgenology
Frank Schwarz, Kathrin Becker, Fanya Lukman, Katharina Melissa Müller, Victoria Sarabhai, Nicole Rauch, Robert Kerberger, Aušra Ramanauskaitė, Robert Sader, Karina Obreja,
To investigate the extension of experimentally induced peri-implantitis lesions under various antiresorptive and antiangiogenic medications.Fourty-eight albino rats had randomly received the following medications (dual application, n = 8 each): (1) amino-bisphosphonate (zoledronate) (Zo), (2) RANKL inhibitor (denosumab) (De), (3) antiangiogenic (bevacizumab) (Be), (4) Zo+Be, (5) De+Be, or (6) no medication (Co). Ligature- and lipopolysaccharide-induced peri-implantitis lesions were established at 2 maxillary implants ...
Tópico(s): Bone Metabolism and Diseases
2023 - Springer Nature | Clinical Oral Investigations
Benson Hsu, Alexander Bondoc, Alex G. Cuenca, Kristin Hittle Gigli, Naomi Laventhal, Thomas A. Nakagawa, Daniel A. Rauch, Tania Fontánez Nieves, Samantha A. House, Charles Vinocur, Nicole Webb, Benson Hsu, Melissa Mauro-Small, Karen Castleberry, Quinn Franklin, Michael S. Leonard, Kristin Hittle Gigli, Nancy D. Hanson, S. Niccole Alexander, Benson Hsu, Nicholas Ettinger, Steven Loscalzo, Lia Lowrie, Elizbeth Mack, Margaret A. Satchell, Linda Siegel, Vijay Srinivasan, Benson Hsu, Elizabeth H. Mack, Shilpa Balikai, Steven Loscalzo, Melanie Kitagawa, Vijay Srinivasan, Samir K. Gadepalli, Tessie W. October, Robert F. Tamburro, Michael S. D. Agus, Mark A. Hall, Nicholas Ettinger, Sue Tellez, Cynthia D. Downard, Kenneth W. Gow, Elizabeth A. Beierle, Marybeth Browne, Barbara A. Gaines, Saleem Islam, Katherine T. Flynn‐O’Brien, Danielle Walsh, Regan Frances Williams, Vivian Thorne, Naomi Laventhal, Gina Marie Geis, Deborah S. Loeff, Kelly N. Michelson, Mary A. Ott, Nanette Elster, Douglas S. Diekema, Maria P. McGee, Kavita Shah Arora, Anjie Emanuel,
This policy statement aims to enhance comfort and increase knowledge of pediatric organ donation and transplantation to the general pediatric community, specifically focusing on the pediatric health care professional and the medical home. The pediatric health care professional will care for neonates, infants, children, and adolescents who may become donors or transplant recipients and, thus, is a crucial member of the pediatric patient's care team. Understanding donation, transplantation, and follow- ...
Tópico(s): Grief, Bereavement, and Mental Health
2023 - American Academy of Pediatrics | PEDIATRICS
JoAnna K. Leyenaar, Vanessa Hill, Quang Vinh Lam, Rebecca Stern, Kristin Williams Vaughan, Daniel A. Rauch, Samantha A. House, Benson Hsu, Melissa Mauro-Small, Nerian Ortiz-Mato, Charles D. Vinocur, Nicole Webb, Vanessa Hill, Kimberly Ernst, Quang Vinh Lam, Michael S. Leonard, Karen Castleberry, Nancy D. Hanson, Kristin Hittle Gigli, Barbara Romito, S. Niccole Alexander,
One in four unscheduled hospital admissions for children and adolescents in the United States occurs via direct admission, defined as hospital admission without first receiving care in the hospital's emergency department. The purpose of this policy statement is to present recommendations to optimize the quality and safety of this hospital admission approach for children. Recommendations included in this policy statement provide guidance related to: (i) direct admission written guidelines, (ii) clear ...
Tópico(s): Child and Adolescent Health
2023 - American Academy of Pediatrics | PEDIATRICS
William D. S. Killgore, Jennifer C. Britton, Zachary J. Schwab, Lauren M. Price, Melissa R. Weiner, Andrea L. Gold, Isabelle M. Rosso, Naomi M. Simon, Mark H. Pollack, Scott L. Rauch,
Background Exaggerated amygdala and reduced ventromedial prefrontal cortex (vmPFC) responsiveness during emotional processing have been reported in studies examining individual anxiety disorders. Studies are needed, however, which directly compare activation of amygdalo-cortical circuitry across multiple anxiety disorders within the same study. Here we compared cortico-limbic neurocircuitry across three different anxiety disorders using a well-validated emotional probe task. Methods Sixty-five adult ...
Tópico(s): Mental Health Research Topics
2013 - Wiley | Depression and Anxiety
Patricia K. Kerig, Richard G. Tedeschi, Arnie Cann, Kanako Taku, Emre Şenol-Durak, Lawrence G. Calhoun, Marianne Skogbrott Birkeland, Marianne Bang Hansen, Ines Blix, Øivind Solberg, Trond Heir, Maureen Murdoch, Michele Spoont, Shannon Kehle‐Forbes, Eileen M. Harwood, Nina A. Sayer, Barbara Clothier, Ann Bangerter, Rebecca K. Sripada, P. Pfeiffer, Jessica Rampton, Dara Ganoczy, Sheila A. M. Rauch, Melissa A. Polusny, Kipling M. Bohnert, Ervin Gul, A Karanci, Craig S. Rosen, Afsoon Eftekhari, Jill J. Crowley, Brandy N. Smith, Eric Kuhn, Lindsay Trent, Nicole Martin, Thuy Tran, Josef I. Ruzek, Brittain Mahaffey, Adam Gonzalez, Samantha G. Farris, Michael J. Zvolensky, Evelyn J. Bromet, Benjamin J. Luft, Roman Kotov, Violeta Fernández‐Lansac, Maria Teresa Barreto Crespo, R. E. Mitchell, Kate Brennan, David Curran, Donncha Hanna, Kevin F. W. Dyer,
Journal of Traumatic StressVolume 30, Issue 1 p. 1-3 Issue InformationFree Access Issue Information - TOC First published: 11 February 2017 https://doi.org/10.1002/jts.22165AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable ...
2017 - Wiley | Journal of Traumatic Stress
Nicole A. Short, Megan Lechner, Benjamin McLean, Andrew S. Tungate, Jenny Black, Jennie Buchanan, R. Matthew Reese, Jeffrey D. Ho, Gordon Reed, Melissa Platt, Ralph Riviello, Catherine Rossi, Patricia Nouhan, Carolyn Phillips, Sandra L. Martin, Israel Liberzon, Sheila A. M. Rauch, Kenneth A. Bollen, Ronald C. Kessler, Samuel A. McLean,
Background Approximately, 100,000 US women receive emergency care after sexual assault each year, but no large-scale study has examined the incidence of posttraumatic sequelae, receipt of health care, and frequency of assault disclosure to providers. The current study evaluated health outcomes and service utilization among women in the 6 weeks after sexual assault. Methods Women ≥18 years of age presenting for emergency care after sexual assault to twelve sites were approached. Among those willing ...
Tópico(s): Criminal Justice and Corrections Analysis
2020 - Wiley | Depression and Anxiety
Michael R. Comeau, Richard D. Johnson, Robert DuBose, Melissa Petersen, Patrick Gearing, Tim VandenBos, Linda Park, Terry Farrah, R. Mark L. Buller, Jeffrey I. Cohen, L Strockbine, Charles T. Rauch, Melanie K. Spriggs,
The vaccinia virus A39R protein is a member of the semaphorin family. A39R.Fc protein was used to affinity purify an A39R receptor from a human B cell line. Tandem mass spectrometry of receptor peptides yielded partial amino acid sequences that allowed the identification of corresponding cDNA clones. Sequence analysis of this receptor indicated that it is a novel member of the plexin family and identified a semaphorin-like domain within this family, thus suggesting an evolutionary relationship between ...
Tópico(s): Axon Guidance and Neuronal Signaling
1998 - Cell Press | Immunity
Cora C. Breuner, Elizabeth M. Alderman, Jennifer A. Jewell, Cora C. Breuner, Elizabeth M. Alderman, Jennifer A. Jewell, Elise D. Berlan, Richard J. Chung, Michael Colburn, Laura K. Grubb, Janet Lee, Stephenie Wallace, Makia E. Powers, Krishna K. Upadhya, Anne-Marie Amies, Liwei L. Hua, Ellie Vyver, Seema Menon, Lauren B. Zapata, Maria H. Rahmandar, Karen Smith, James Baumberger, Daniel A. Rauch, Samantha A. House, Benson Hsu, Melissa Mauro-Small, Nerian Ortiz-Mato, Charles Vinocur, Nicole Webb, Kimberly Ernst, Vinh Lam, Michael S. Leonard, Karen Castleberry, Nancy D. Hanson, Kristin Hittle Gigli, Barbara Romito, S. Niccole Alexander,
This policy statement is the first published statement in the United States on this topic and the authors aim to provide pediatricians with evidence-based information on the unique aspects required to care for hospitalized adolescents. Included in this policy statement is a description of the possible effects hospitalization may have on the developmental and emotional progress of adolescence, the role of the hospital setting, the importance of confidentiality, and issues related to legal/ethical ...
Tópico(s): Child and Adolescent Health
2023 - American Academy of Pediatrics | PEDIATRICS
Maya Guhan, Stacey Crane, Lillian S. Valerius, Denise De La Cruz, Benjamin D. Smith, Wendy A. Woodward, Melissa P. Mitchell, Vicente Valero, Gaiane M. Rauch, Savitri Krishnamurthy, Carla L. Warnecke, Henry M. Kuerer, Simona F. Shaitelman,
Purpose Advances in radiation therapy have enabled the ability to deliver ablative treatments, but there has been limited application of these treatments to early-stage breast cancers with a goal of omitting surgery. The purpose of this study was to explore patient interest in pursuing nonsurgical treatment approaches for their early-stage breast cancer. Methods and Materials We conducted a qualitative study involving interviews with 21 patients with early-stage breast cancer who were eligible for ...
Tópico(s): Cancer survivorship and care
2023 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics
Helen M. Johnson, Heather Lin, Yu Shen, Emilia J. Diego, Savitri Krishnamurthy, Wei Yang, Benjamin D. Smith, Vicente Valero, Anthony Lucci, Susie X. Sun, Simona F. Shaitelman, Melissa P. Mitchell, Judy C. Boughey, Richard L. White, Gaiane M. Rauch, Henry M. Kuerer, Tanya W. Moseley, Jessica WT Leung, Monica L. Huang, Rosalind P. Candelaria, Beatriz E. Adrada, Elsa Arribas, Raquel FD van la Parra, Kelly K. Hunt, Isabelle Bedrosian, Mediget Teshome, Rosa F. Hwang, Makesha Miggins, Matthew J. Piotrowski, Ana P Refinetti, Richard A. Ehlers, Jessica Suarez Colen, Catherine Loveland‐Jones, Beth Ann Lesnikowski, Laila Samiian, Clayton Chong,
Patients should have an active role in decisions about pursuing or forgoing specific therapies in treatment de-escalation trials.To evaluate longitudinal patient-reported outcomes (PROs) encompassing decisional comfort and health-related quality of life (HRQOL) among patients who elected to enroll in a clinical trial evaluating radiotherapy alone, without breast surgery, for invasive breast cancers with exceptional response to neoadjuvant systemic therapy (NST).Prospective, single-group, phase 2 clinical ...
Tópico(s): Global Cancer Incidence and Screening
2023 - American Medical Association | JAMA Network Open
Ilse Meerschaut, Shana De Coninck, Wouter Steyaert, Angela Barnicoat, Allan Bayat, Francesco Benedicenti, Siren Berland, Edward Blair, Jeroen Breckpot, Anna de Burca, Anne Destrėe, Sixto García‐Miñaúr, Andrew Green, Bernadette Hanna, Kathelijn Keymolen, Marion Koopmans, Damien Lederer, Melissa Lees, Cheryl Longman, Sally Ann Lynch, Alison Male, F. Ellis McKenzie, Isabelle Migeotte, Ercan Mıhçı, Banu Nur, Florence Petit, Juliette Piard, Frank Plasschaert, Anita Rauch, Pascale Ribaı̈, Iratxe Salcedo Pacheco, Franco Stanzial, Irene Stolte‐Dijkstra, Irene Valenzuela, Vinod Varghese, Pradeep Vasudevan, Emma Wakeling, Carina Wallgren‐Pettersson, Paul Coucke, Anne De Paepe, Daniël De Wolf, Sofie Symoens, Bert Callewaert,
Congenital contractural arachnodactyly (CCA) is an autosomal dominant connective tissue disorder manifesting joint contractures, arachnodactyly, crumpled ears, and kyphoscoliosis as main features. Due to its rarity, rather aspecific clinical presentation, and overlap with other conditions including Marfan syndrome, the diagnosis is challenging, but important for prognosis and clinical management. CCA is caused by pathogenic variants in FBN2, encoding fibrillin-2, but locus heterogeneity has been ...
Tópico(s): Congenital limb and hand anomalies
2019 - Elsevier BV | Genetics in Medicine