... with the expansion. In this article, we appraise MiHoYo Co., Ltd., a digital game development and publishing ... business administration, we analyze the competitive advantages of MiHoYo. MiHoYo has released best-selling video games with themes ... enhances its lead in competition; at reasonable prices; MiHoYo’s original intellectual properties have attracted a large number of users with high consumer stickiness. Moreover, MiHoYo has a culture of prioritizing technology and setting ... gathering experience in business management. The success of MiHoYo under the challenges posed by the game development ...
Tópico(s): Asian Culture and Media Studies
2023 - | Highlights in Business Economics and Management
Tara Fickle, Christopher B. Patterson,
... the Mass Effect series (BioWare, 2007–), Genshin Impact (miHoYo, 2020), and Divinity: Original Sin 2 (Larian Studios, ...
Tópico(s): Management and Organizational Studies
2022 - Taylor & Francis | Critical Studies in Media Communication
Toshifumi Dohi, Hirotaka Sasa, Keitaro Miyazaki, Mihoyo Fujitake, Naoko Takenaga, Yasuyuki Kita,
A new type of binaphthyl-based chiral iodide functionalized at positions 8 and 8' of the naphthalene rings has been found as a promising structural motif for the asymmetric hypervalent iodine(III) oxidations, specifically, for the dearomatizing spirocyclization of naphthol carboxylic acids showing expectedly better enantioselectivities versus other atropisomeric biaryls, i.e., a conventionally used binaphthalene having the diiodides in the minor groove.
Tópico(s): Alkaloids: synthesis and pharmacology
2017 - American Chemical Society | The Journal of Organic Chemistry
Yoshihide Usami, Kyoko Nakagawa‐Goto, Jing-Yu Lang, Yoon Kim, Chin-Yu Lai, Masuo Goto, Nobuko Sakurai, Masahiko Taniguchi, Toshiyuki Akiyama, Susan L. Morris‐Natschke, Kenneth F. Bastow, Gordon M. Cragg, David Newman, Mihoyo Fujitake, Koichi Takeya, Mien‐Chie Hung, Eva Y.-H.P. Lee, Kuo‐Hsiung Lee,
A new quassinoid, designated 2'-(R)-O-acetylglaucarubinone (1), and seven known quassinoids (2-8) were isolated, using bioactivity-guided separation, from the bark of Odyendyea gabonensis (Pierre) Engler [syn. Quassia gabonensis Pierre]. The structure of 1 was determined by spectroscopic analysis and by semisynthesis from glaucarubolone. Complete (1)H and (13)C NMR assignments of compounds 1-8 were also established from detailed analysis of two-dimensional NMR spectra, and the reported configurations ...
Tópico(s): Multicomponent Synthesis of Heterocycles
2010 - American Chemical Society | Journal of Natural Products
Satoru Sakuma, Masahiko Nakanishi, Kazuhiro Morinaga, Mihoyo Fujitake, Shun‐ichi Wada, Yukari Fujimoto,
Tópico(s): Folate and B Vitamins Research
2010 - Elsevier BV | Food and Chemical Toxicology
Koji Fujita, Yuichi Nozaki, Koichiro Wada, Masato Yoneda, Yoko Fujimoto, Mihoyo Fujitake, Hiroki Endo, Hirokazu Takahashi, Masahiko Inamori, Noritoshi Kobayashi, Hiroyuki Kirikoshi, Kensuke Kubota, Satoru Saito, Atsushi Nakajima,
The specific mechanisms of nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH) pathogenesis remain unknown. In the present study we investigated the differences between NAFL and NASH in terms of liver lipid metabolites and serum lipoprotein. In all, 104 Japanese subjects (50 men and 54 postmenopausal women) with histologically verified NAFL disease (NAFLD) (51 with NAFL, 53 with NASH) were evaluated; all diagnoses were based on liver biopsy findings and the proposed diagnostic criteria. ...
Tópico(s): Cancer, Lipids, and Metabolism
2009 - Lippincott Williams & Wilkins | Hepatology
Mihoyo Fujitake, Shinya Harusawa, Lisa Araki, Maho Yamaguchi, David M.J. Lilley, Zheng-yun Zhao, Takushi Kurihara,
Abstract Nucleoside phosphoramidites (PAs) are the most widely used building blocks in contemporary solid-phase synthesis of oligonucleotides. The accurate molecular weight (MW) measurements of such molecules, which contain acid-labile moieties, may be easily determined by mass spectrometry using a matrix system, triethanolamine (TEOA)–NaCl, on liquid secondary ion mass spectrometry (LSIMS) equipped with a double-focusing mass spectrometer. The present method measures rapidly and easily the accurate ...
Tópico(s): HIV/AIDS drug development and treatment
2005 - Elsevier BV | Tetrahedron
Keiichi Nomura, Sachiko Nakamura, Mihoyo Fujitake, Tetsu Nakanishi,
The complete amino acid sequence of Japanese chestnut (Castanea crenata Sieb. et Zucc.) agglutinin (CCA) was determined. Analysis by SIMS of the acidic peptide obtained by pepsin digestion revealed that the N-terminal amino acid sequence should be Acetyl-Met-Glu-Glu. Prior to sequence analysis, redetermination of cysteine residues indicated the presence of one cysteine residue per subunit. The complete sequence was determined by endoproteinase Arg-C and Achromobacter protease I digestion, and CNBr ...
Tópico(s): Glycosylation and Glycoproteins Research
2000 - Elsevier BV | Biochemical and Biophysical Research Communications
Shinya Harusawa, Hiroki Yoneyama, Daiki Fujisue, Masayoshi Nishiura, Mihoyo Fujitake, Yoshihide Usami, Zheng-yun Zhao, Scott A. McPhee, Timothy J. Wilson, David M.J. Lilley,
Novel C5-linked C0- and C2-tetrazole ribonucleoside phosphoramidites were designed and synthesized via tetrazole C-nucleosides. Pivaloyloxymethyl (POM) and methyl-substituted POM (MePOM) groups were introduced as N-protecting groups in the tetrazole ring that can be readily removed under mild basic conditions. The phosphoramidites were successfully incorporated into the VS ribozyme substrate and hence providing a chemogenetic approach to determine which nucleobases of ribozymes function as the acid ...
Tópico(s): Chemical Synthesis and Analysis
2012 - Elsevier BV | Tetrahedron Letters
... a case study of Genshin Impact IP under Mihoyo brand, summarizes the thinking model according to the ...
Tópico(s): Innovative Educational Techniques
2024 - | Highlights in Business Economics and Management
Xiaomin Cai, Yidi Chen, Yuhan Mao, Liang Cai,
... a mobile hit game developed by Chinese -based miHoYo, this paper discusses the strategy of integrating Chinese ...
Tópico(s): Impact of Technology on Adolescents
2023 - Springer Science+Business Media | Communications in computer and information science
Atsumi Sasayama, Keiko Akita, Hiroto Oya, Takashi Kikuchi, Yasuko In, Mihoyo Fujitake, Takeshi Yamada, Reiko Tanaka,
Abstract Two novel chukrasone‐type limonoids, Guianofruits A and B ( 1 and 2 ) were isolated from the fruit oil of Carapa guianensis A UBLET (Meliaceae), a traditional medicine in Brazil and Latin American countries. Their structures were elucidated based on spectroscopic analyses using 1D and 2D NMR techniques, HRFABMS, and X‐ray crystallography. Compounds 1 and 2 were rare chukrasone‐type limonoids that had once been isolated from Chukrasia tabularis . Compounds 1 and 2 were evaluated for their effects ...
Tópico(s): Insect Pest Control Strategies
2018 - Wiley | ChemistrySelect
Jingwei Bi, Shuyuan Hu, Zixi Lin, Zhangyang Ying,
... of the video game industry by taking Shanghai MiHoYo.Network Technology Co. It summarizes the role of ...
Tópico(s): Digital Games and Media
2024 - | Highlights in Business Economics and Management
Tópico(s): E-commerce and Technology Innovations
2025 - | Highlights in Business Economics and Management
Tópico(s): Digital Games and Media
2025 - | Highlights in Business Economics and Management
2025 - | Highlights in Business Economics and Management
Tópico(s): Digital Games and Media
2024 - Atlantis Press | Advances in economics, business and management research/Advances in Economics, Business and Management Research
Shinya Harusawa, Mihoyo Fujitake, Takushi Kurihara, Zhengyun Zhao, David M.J. Lilley,
Abstract Nucleoside phosphoramidites are the most widely used building blocks in contemporary solid‐phase synthesis of oligonucleotides. The accurate molecular weight measurements of such molecules, which are acid‐labile compounds, may be easily determined by mass spectrometry using a matrix system, triethanolamine/NaCl, on a liquid secondary ion mass spectrometer (LSIMS) or fast‐atom bombardment (FAB) MS equipped with a double‐focusing mass spectrometer. The present method rapidly and easily measures ...
Tópico(s): Mass Spectrometry Techniques and Applications
2006 - Wiley | Current Protocols in Nucleic Acid Chemistry
... flow and revenue of Tencent games, Netease games, Mihoyo games. Through analysis, this paper analyzes the financial ...
Tópico(s): Business Strategy and Innovation
2024 - | Highlights in Business Economics and Management
Hardianto Rahardjo, Dinda Gayatri,
Genshin Impact is a video game developed by miHoYo, a Shanghai based video game developer and animation ...
2021 - | Review of International Geographical Education Online
Hideyasu China, Hotaka Yatabe, Nami Kageyama, Mihoyo Fujitake, Kotaro Kikushima, Toshifumi Dohi,
Tópico(s): Alkaloids: synthesis and pharmacology
2020 - Springer Science+Business Media | Russian Chemical Bulletin
室，ESR 室および数種の分析機器を備えた三つ の測定室などとともに，中央機器研究施設に設けられてい ます．NMR 室と MS 室はそれぞれ専任の教員が管理して おりますが，他は各研究室単独または共同で購入され，他 の教員や学生さんにも開放されています． 質量分析装置としては，MS 室に設置している日本電子 JMS-700 (2)二重収束質量分析計(写真 1)に加え，マト リックス支援レーザー脱離イオン化飛行時間型質量分析 計，ultra performance liquid chromatograph tandem mass spectrometer(UPLC-MS/MS) ， ガスクロマトグラフ質量 分 析 計(gas chromatograph mass spectrometer: GC-MS) ， 誘導結合プラズマ質量分析計がありますが，本稿では，私 が担当する MS 室について私の採用時に遡って紹介させて いただきたいと思います． 2. 大阪薬科大学移転前の質量分析室 私が大阪薬科大学 薬品化学(現，医薬分子化学)研究室に採用された三十数年前，共同研究センターのような形態は なく，各種機器は離れた部屋に点在しており， ...
Tópico(s): Synthesis and biological activity
2018 - Mass Spectrometry Society of Japan | Journal of the Mass Spectrometry Society of Japan
Showa KASHIWAGI, Momoka Matsushita, Kanako Miyachi, Mamiko Asano, Mihoyo Fujitake, Takako Yamaguchi, Hitoshi Matsumura, Yoshikazu Fujita,
A novel spectrophotometric method was established for the determination of spermine based on color complex formation among vanillylfluorone, cobalt(II) and spermine in the presence of stearyltrimethylammonium chloride. In the determination of spermine, Beer's low was obeyed in the range of 0.04 - 1.0 μg mL−1. The effective molar absorptivity at 615 nm and the relative standard deviation were 2.2 × 105 L mol−1 cm−1 and 2.5 % (n = 5), respectively.
Tópico(s): Protein Hydrolysis and Bioactive Peptides
2016 - Japan Society for Analytical Chemistry | BUNSEKI KAGAKU
Mihoyo Fujitake, Shinya Harusawa,
Nucleoside phosphoramidites (PAs) are the most widely used building blocks in the contemporary solid-phase synthesis of oligonucleotides. Accurate molecular weight measurements of such acid-labile compounds may be easily determined in a matrix system comprising triethanolamine (TEOA)-NaCl by liquid secondary ionization mass spectrometry (LSIMS) or fast atom bombardment mass spectrometry (FABMS), using a double-focusing mass spectrometer. The present method rapidly and easily measures the accurate MWs ...
Tópico(s): RNA Interference and Gene Delivery
2013 - Pharmaceutical Society of Japan | YAKUGAKU ZASSHI
Aki Harada, Sayaka Ito, Kimiye Baba, Toshiki Koda, Tomoki Suizu, Mihoyo Fujitake, Takako Yamaguchi, Yoshikazu Fujita,
アシタバ含有カルコン誘導体の4-Hydroxyderricin（以後｛Hy｝とする）及びXanthoangelol（以後｛Xa｝とする）を用いるチタン（IV）の新規吸光光度法を開発した．｛Hy｝の場合，モル吸光係数（ε）は，ε＝6.24×104 L mol－1 cm－1，相対標準偏差（RSD）は0.65％（n＝6），｛Xa｝の場合ε＝6.02×104 L mol－1 cm－1，RSD＝0.53％（n＝6）であった．｛Hy｝と｛Xa｝は共に，従来のチタン（IV）吸光光度法に比べ，共存物質の影響も極めて受けにくく，選択性にも優れている．また，本法を，酸化チタン含有用品中のチタン（IV）分析に応用したところ，測定値，回収率とも良好な結果が得ることができた．これらの天然色素が分析用有機試薬として十分利用できることを認めた．
Tópico(s): Synthesis of Organic Compounds
2009 - Japan Society for Analytical Chemistry | BUNSEKI KAGAKU