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Artigo Acesso aberto Revisado por pares

Sergey Aganezov, Sara Goodwin, Rachel M. Sherman, Fritz J. Sedlazeck, Gayatri Arun, Sonam Bhatia, Isac Lee, Melanie Kirsche, Robert Wappel, Melissa Kramer, Karen Kostroff, David L. Spector, Winston Timp, W. Richard McCombie, Michael C. Schatz,

Improved identification of structural variants (SVs) in cancer can lead to more targeted and effective treatment options as well as advance our basic understanding of the disease and its progression. We performed whole-genome sequencing of the SKBR3 breast cancer cell line and patient-derived tumor and normal organoids from two breast cancer patients using Illumina/10x Genomics, Pacific Biosciences (PacBio), and Oxford Nanopore Technologies (ONT) sequencing. We then inferred SVs and large-scale allele- ...

Tópico(s): Genomics and Rare Diseases

2020 - Cold Spring Harbor Laboratory Press | Genome Research

Artigo Acesso aberto Revisado por pares

Steven Singh, Robert DiBianco, Michael Davidov, John S. Gottdiener, W L Johnson, Atul Laddu, Ross D. Fletcher,

... date: 1-May-1985. Singh S, DiBlanco R, Kostroff L and Fletcher R (1984) Lorcainide for high- ...

Tópico(s): Cardiac Arrhythmias and Treatments

1982 - Lippincott Williams & Wilkins | Circulation