Ernest Newman, Edward Lyttelton, Gerard Hopkins, Yarborough, Jessiel. Smith, Chris Bale, Ralph Straus, Rev. Archibald Fleming, J. L. S., Eric Newton, Norman Crump City Editor, James Agate, Julia Herrick, Milward Kennedy, Diarist, George R. I., D. R. Gent, Desmond MacCarthy, Atticus, Maria S. Steuart, Edward Shanks, Dilys Powell, Austin Reed, W. L. Hosking, E. L. S. Horsburgh, Lord Elton, J. A. F., John Gore, R. C. K. Ensor,
... Well with the Music Hall The Dramatic World Schenker & the Composer The World of Music Christmas Books ... The Compleat Lover. An anthology by William Geoffrey. (Michael Joseph. 7s. 6d.) The Foundations of Empirical Knowledge. ...
1940 - Gale Group | Sunday Times HA GDA
Produção Nacional
Revisado por pares
David P. Carbone, Tudor‐Eliade Ciuleanu, Michael Schenker, Manuel Cobo, Stéphanie Bordenave-Juchereau, Óscar Juan, J. Menezes, Niels Reinmuth, Eduardo Richardet, Ying Cheng, Hideaki Mizutani, Enriqueta Felip, Bogdan Żurawski, Aurelia Alexandru, Luis Paz‐Ares, Shun Lu, Thomas John, Xiaoqing Zhang, Javed Mahmood, Nan Hu, Tuli De, Irene Santi, John R. Penrod, Yong Yuan, Adam Lee, Martin Reck,
Background In CheckMate 9LA, nivolumab plus ipilimumab with chemotherapy prolonged overall survival (OS) versus chemotherapy regardless of tumor PD-L1 expression or histology. We report updated efficacy and safety in all randomized patients with a minimum 4-year follow-up and an exploratory treatment-switching adjustment analysis in all treated patients who received chemotherapy and subsequent immunotherapy. Methods Adults with stage IV/recurrent non-small cell lung cancer (NSCLC), no sensitizing ...
Tópico(s): Pancreatic and Hepatic Oncology Research
2024 - BMJ | Journal for ImmunoTherapy of Cancer
Piaras Beaslai, Ernest Newman, A. B., Mr. Chamberlain, S. W. John Murray, A. T. Johnson, Henry Longhurst, H. S. Shelton, Hon. Lord Hewart, Irwin Bevan, L. A. Pavey, Yarborough, David Hunter-Blair, G. W. Younger, Ralph Straus, L. A. G. Strong, Edward Shoosmith, Herbert Sidebotham, A. Whitworth, Alfred Praga, Mark Kerr, J. M. Bulloch, Richard Clowes, J. C. Squire, R. C., Doreen Wallace, Walter Dexter, Eric Newton, E. V. Lucas, James Stephens, H. Woodward, James Agate, Ernest A. Ebblwehite, Lord Baden-Powell, Ernest Yaldwyn, Milward Kennedy, W. Kent, W. Wilberforch, W. D. H. McCullough, Sydney W. Carroll, E. W. Hendy, Basil Maine, Sir Charles Tegart, D. R. Gent, Desmond MacCarthy, Philip Morrell, A. G. C., Lady Muriel Beckwith, Lord Birkenhead's, H. W. Brekke, J. Hanbury-Williams, C. L., Sir W. Braithwaite, R. L. Hollands, A. E. Sullivan, J. F. Birtwhistle, Edward Shanks, E. D. Telford, G. M. Young, Bruce Bruce-Porter, Newman Flower, Jacques Emile Blanche, H. E. Symons, Pandora, H. F., Hamilton Price, M. A. Mainwaring, John Stainton, J. Henderson Stewart, N. C. W. Edge, K. Clarke,
... Items More about Conducting The World of Music Schenker on Notation Recitals of the Week Jacques String ... 8s. 6d.) Lost Survivor. By L. A. Pavey. (Michael Joseph. 7s. 6d.) The Sailor's Holiday. By ...
1937 - Gale Group | Sunday Times HA GDA
Thierry André, Elena Élez, Eric Van Cutsem, Lars Henrik Jensen, Jaafar Bennouna, Guillermo Méndez, Michael Schenker, Christelle de la Fouchardière, María Luisa Limón, Takayuki Yoshino, Jin Li, Heinz‐Josef Lenz, José Luis Manzano Mozo, Giampaolo Tortora, Rocio García‐Carbonero, Elvis Cela, Yingsi Yang, Ming Lei, Lixian Jin, Sara Lonardi,
LBA768 Background: Patients (pts) with MSI-H/dMMR mCRC have poor outcomes with standard chemo ± targeted therapies. NIVO ± IPI are approved in previously treated pts with MSI-H/dMMR mCRC in many countries, based on the phase 2 CheckMate 142 study. CheckMate 8HW (NCT04008030) is a randomized phase 3 study comparing NIVO + IPI with NIVO or chemo in pts with MSI-H/dMMR mCRC. We report progression-free survival (PFS) by blinded independent central review (BICR) at a prespecified interim analysis for NIVO + IPI ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2024 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Andrew Robson, Phil Yates, Jon Ashworth, Suely Kennedy, Charles Darwin, David Charter Health Correspondent, Helen Studd, Robert Cole, Andrew Pierce, Michael Paul, James Moore, Frances Gibb Legal Editor, Simon Barnes, Robert Thicknesse, Roland Watson and John O'Leary, Claire McDonald, Mark Souster, Martin Richards, David Rhys Jones, Dearbail Jordon, Richard Hobson, Roy Porter, Sally Emerson, Ivo Tennant, Alan C. Newell, Professor, John Ray, Ben Webster and Michael Binyon, Peter Tatchell, Jane Bolton, Philip Howard, David Chater, Michael Binyon, Joanna Bale, James Bone, Penny Wark, James Landale and Allan Hall, Clive Fewins, Gabrielle Starkey, Marion Shoard, Dick Pantlin, Geoff Brown, Pam Giddy, Director, Stewart Tendler and Ian Cobain, Giles Coren, Andrew Norfolk, Joe Joseph, Jonathan Collins, David Lister and Michael Evans Defence Editor, Steve Bird, Philip Hobsbaum, Robert Welding, Alix Ramsay Tennis Correspondent, Tim Reid, Richard Ford Home Correspondent, Alan Hamilton, Oliver Wright, Robert Nye, Muir Hunter, Nick Wyke, Helen Rumbelow and Melissa Kite, Helen Nugant, Tom Baldwin Glen Owen and Dominic Kennedy, Adrian Reynold, H. B. Amin, Richard Turner, Peter Barnard, Mark Court, Clive Mathieson Telecoms Correspondent, Caroline Merrell Banking Correspondent, Rose Rouse, Angela Jameson, Jake Arnott, Russell Kempson, Paula Hawkins, Vanora Bennett, Richard Cork, Geoffrey Alderman, Oliver Kay, Matt Dickinson Football Correspondent, Mark Henderson Science Correspondent, Sam Coates, Christopher Martin-Jenkins, Christopher Irvins, Diana Cambridge, Barry Millington, Ian Brunskill, Simon de Bruxelles, S. Chomet, John Hopkins Golf Correspondent, Rob Wright, Karen Homer, Peter B. Baker, Iain Finlavson, Raymond Keene, Steve Howey, Lewis Smith, Clive Mathieson, John Russell Taylor, Cheryl Taylor, Arnold Wolfendale, President, Philip Webster and Roland Watson, Mary Ann, David Crease, Greg Hurst Parliamentary Correspondent, Stephen d'Antal, Christopher Walker Chief Ireland Correspondent, Sarah Schenker, Steven Rose, Oliver Holt, Richard Owen, Roger Boyes, Ian Cobain and Stewart Tendler, Oliver August, Nick Hasell, Seamus Heaney, Dalya Alberge, Nick Szczepanik, John Goodbody, Anne Ashworth, James Doran, Giles Whittell, Melissa Kite Political Correspondent, Robert Crampton, Tim Hames, Emma Tennant, Ian Johns, Gwenda Brophy, Kevin McCarra, Matthew Parris, Fay Weldon, George Caulkin, Chris McGrath, Russell Jenkins, Dearbail Jordan, Alan Lee, Peter Riddell, Ben MacIntyre, Harry Cayton, Chief Executive, Rachel Campbell-Johnson, Richard Miles, Jason Cowley, Simon Jenkins, Gary Duncan Economics Correspondent, Martin Waller, Chris Ayres, Clive Hawkins, James Jackson, Alan Coren, Nigel Hawkes Health Editor, Laura Peek, John Goodbody Sports Reporter, Graeme Peters, Alyson Rudd, Sam Kiley, Alice Miles, John Phillips, Allan Hall, Alan Lee Racing Correspondent, Tom Baldwin and Andrew Pierce, Jan Raath, Sally Huxley, Patience Wheatcroft, Mant Hargie,
... scheme to put their work in unlikely places. Michael Binyon joins the ride Around the galleries No ...
2001 - Gale Group | TDA
Produção Nacional
Revisado por pares
Yelena Y. Janjigian, Jaffer A. Ajani, Markus Moehler, Lin Shen, Marcelo Garrido, Carlos Gallardo, Lucjan Wyrwicz, Kensei Yamaguchi, James M. Cleary, Elena Elimova, Michalis V. Karamouzis, Ricardo Brugés, Tomasz Skoczylas, Arinilda Bragagnoli, Tianshi Liu, Mustapha Tehfé, Thomas Zander, Rubén Dario Kowalyszyn, Roberto Pazo-Cid, Michael Schenker, Kynan Feeny, Rui Wang, Ming Lei, Clara Chen, Raheel Nathani, Kohei Shitara,
JCO
Tópico(s): Cancer Immunotherapy and Biomarkers
2024 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Michael Schenker, Mauricio Burotto, Martin Eduardo Richardet, Tudor‐Eliade Ciuleanu, Anthony Gonçalves, Neeltje Steeghs, Patrick Schöffski, Paolo A. Ascierto, Michele Maio, Iwona Ługowska, Lorena Lupinacci, Alexandra Léary, Jean‐Pierre Delord, Julieta Grasselli, David S.P. Tan, Jennifer Friedmann, Jacqueline Vuky, Marina Tschaika, Somasekhar Konduru, Sai Vikram Vemula, Ruta Slepetis, Georgia Kollia, Misena Pacius, Quyen Duong, Ning Huang, Parul Doshi, Jonathan Baden, Massimo Di Nicola,
Checkpoint inhibitor therapy has demonstrated overall survival benefit in multiple tumor types. Tumor mutational burden (TMB) is a predictive biomarker for response to immunotherapies. This study evaluated the efficacy of nivolumab+ipilimumab in multiple tumor types based on TMB status evaluated using either tumor tissue (tTMB) or circulating tumor DNA in the blood (bTMB).
Tópico(s): Lung Cancer Treatments and Mutations
2024 - BMJ | Journal for ImmunoTherapy of Cancer
Matthew D. Galsky, J. Alfred Witjes, Jürgen E. Gschwend, Matthew I. Milowsky, Michael Schenker, Begoña P. Valderrama, Yoshihiko Tomita, Aristotelis Bamias, Thierry Lebrét, Shahrokh F. Shariat, Se Hoon Park, Mads Agerbæk, Gautam Jha, Frank Stenner, Dingwei Ye, Fabio Giudici, Santanu Dutta, Margarita Askelson, Federico Nasroulah, Joshua Zhang, Lynne Brophy, Dean F. Bajorin,
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has already been reported . CheckMate 274 is a phase III, randomized, double-blind trial of adjuvant nivolumab ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2024 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Produção Nacional
Revisado por pares
Peter R. Galle, Thomas Decaens, Masatoshi Kudo, Shukui Qin, Leonardo Goliatt, Bruno Sangro, Hatim Karachiwala, Joong‐Won Park, Edward Gane, Matthias Pinter, David Tai, Armando Santoro, Gonzalo Pizarro, Chang‐Fang Chiu, Michael Schenker, Aiwu Ruth He, Qi Wang, Caitlyn Stromko, Joseph Hreiki, Thomas Yau,
LBA4008 Background: First-line therapies based on programmed death ligand 1 (PD-L1) inhibitors are standard of care (SOC) in uHCC and demonstrate improved outcomes over SOR; however, prognosis remains poor and there is an unmet need for alternative therapies with long-term benefits. Second-line NIVO + IPI demonstrated clinically meaningful efficacy and manageable safety in SOR-treated patients (pts) with HCC in CheckMate 040, leading to its accelerated approval in the United States. We report first results ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2024 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Thierry André, Elena Élez, Eric Van Cutsem, Lars Henrik Jensen, Jaafar Bennouna, Guillermo Méndez, Michael Schenker, Christelle de la Fouchardière, María Luisa Limón, Takayuki Yoshino, Jin Li, Heinz‐Josef Lenz, José Luis Manzano Mozo, Giampaolo Tortora, Rocio García‐Carbonero, Laëtitia Dahan, Myriam Chalabi, Rohit Joshi, Eray Goekkurt, Maria Ignez Braghiroli, Timuçin Çil, Elvis Cela, Tian Chen, Ming Lei, Matthew Dixon, Sandzhar Abdullaev, Sara Lonardi,
BackgroundPatients with microsatellite-instability–high (MSI-H) or mismatch-repair–deficient (dMMR) metastatic colorectal cancer have poor outcomes with standard chemotherapy with or without targeted therapies. Nivolumab plus ipilimumab has shown clinical benefit in nonrandomized studies of MSI-H or dMMR metastatic colorectal cancer.MethodsIn this phase 3 open-label trial, we randomly assigned patients with unresectable or metastatic colorectal cancer and MSI-H or dMMR status according to local testing ...
Tópico(s): Colorectal Cancer Treatments and Studies
2024 - Massachusetts Medical Society | New England Journal of Medicine
Michiel S. van der Heijden, Guru Sonpavde, Thomas Powles, Andrea Necchi, Mauricio Burotto, Michael Schenker, Juan Pablo Sade, Aristotelis Bamias, Philippe Beuzeboc, Jens Bedke, Jan Oldenburg, Gurkamal Chatta, Yüksel Ürün, Dingwei Ye, Zhisong He, Begoña P. Valderrama, Ja Hyeon Ku, Yoshihiko Tomita, Jeiry Filian, Lily Wang, Daniela Purcea, M. PATEL, Federico Nasroulah, Matthew D. Galsky,
No new agent has improved overall survival in patients with unresectable or metastatic urothelial carcinoma when added to first-line cisplatin-based chemotherapy.In this phase 3, multinational, open-label trial, we randomly assigned patients with previously untreated unresectable or metastatic urothelial carcinoma either to receive intravenous nivolumab (at a dose of 360 mg) plus gemcitabine-cisplatin (nivolumab combination) every 3 weeks for up to six cycles, followed by nivolumab (at a dose of 480 ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2023 - Massachusetts Medical Society | New England Journal of Medicine
Produção Nacional
Revisado por pares
Thierry André, Elena Élez, Heinz‐Josef Lenz, Lars Henrik Jensen, Yann Touchefeu, Eric Van Cutsem, Rocio García‐Carbonero, David Tougeron, Guillermo Ariel Mendez, Michael Schenker, Christelle de la Fouchardière, María Luisa Limón, Takayuki Yoshino, Jin Li, José Luis Manzano Mozo, Laëtitia Dahan, Giampaolo Tortora, Myriam Chalabi, Eray Goekkurt, Maria Ignez Braghiroli, Rohit Joshi, Timuçin Çil, F. Aubin, Elvis Cela, Tian Chen, Ming Lei, Lixian Jin, Steven I. Blum, Sara Lonardi,
Tópico(s): Cancer Immunotherapy and Biomarkers
2025 - Elsevier BV | The Lancet
Produção Nacional
Revisado por pares
Martin Reck, Tudor‐Eliade Ciuleanu, Michael Schenker, Stéphanie Bordenave-Juchereau, Manuel Cobo, Óscar Juan, Niels Reinmuth, Eduardo Richardet, Enriqueta Felip, J. Menezes, Ying Cheng, Hideaki Mizutani, Bogdan Żurawski, Aurelia Alexandru, David P. Carbone, Shun Lu, Thomas John, Takekazu Aoyama, Diederik J. Grootendorst, Nan Hu, Laura J. Eccles, Luis Paz‐Ares,
We report 5-year efficacy and safety outcomes from CheckMate 9LA in patients with metastatic non-small cell lung cancer (mNSCLC) and exploratory analyses in key patient subgroups.
Tópico(s): Lung Cancer Treatments and Mutations
2024 - Elsevier BV | European Journal of Cancer
Georgina V. Long, Dirk Schadendorf, Michele Del Vecchio, James Larkin, Victoria Atkinson, Michael Schenker, Jacopo Pigozzo, Helen Gogas, Stéphane Dalle, Nicolás Meyer, Paolo A. Ascierto, Shahneen Sandhu, Thomas Eigentler, Ralf Gutzmer, Jessica C. Hassel, Caroline Robert, Matteo S. Carlino, Anna Maria Di Giacomo, Marcus O. Butler, Eva Muñoz‐Couselo, Michael P. Brown, Piotr Rutkowski, Andrew Haydon, Jean‐Jacques Grob, Jacob Schachter, Paola Queirolo, Alexander Menzies, Sandra Re, Tuba Öcek Baş, Veerle de Pril, Daniel J. Tenney, Hao Tang, Jeffrey S. Weber,
... Schadendorf, Michele Del Vecchio, James Larkin, Victoria Atkinson, Michael Schenker, Jacopo Pigozzo, Helen J. Gogas, Stéphane Dalle, Nicolas Meyer, Paolo A. Ascierto, Shahneen Sandhu, Thomas Eigentler, Ralf Gutzmer, Jessica C. Hassel, Caroline Robert, Matteo Carlino, Anna Maria Di Giacomo, Marcus O. Butler, Eva Muñoz-Couselo, Michael P. Brown, Piotr Rutkowski, Andrew Haydon, Jean-Jacques ...
Tópico(s): Immunotherapy and Immune Responses
2021 - American Association for Cancer Research | Cancer Research
Anushree Tripathi, Michael Spedding, Esther Schenker, Michael Didriksen, Arnaud Cressant, Thérèse M. Jay,
Abstract Genetic microdeletion at the 22q11 locus is associated with very high risk for schizophrenia. The 22q11.2 microdeletion (Df(h22q11)/+) mouse model shows cognitive deficits observed in this disorder, some of which can be linked to dysfunction of the prefrontal cortex (PFC). We used behavioral ( n = 10 per genotype), electrophysiological ( n = 7 per genotype per group), and neuroanatomical ( n = 5 per genotype) techniques to investigate schizophrenia-related pathology of Df(h22q11)/+ mice, which showed ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2020 - Springer Nature | Translational Psychiatry
Michael Schenker, Mauricio Burotto, Martin Eduardo Richardet, Tudor‐Eliade Ciuleanu, Anthony Gonçalvès, Neeltje Steeghs, Patrick Schöffski, Paolo A. Ascierto, Michele Maio, Iwona Ługowska, Lorena Lupinacci, Alexandra Léary, Jean‐Pierre Delord, Julieta Grasselli, David S.P. Tan, Jennifer Friedmann, Jacqueline Vuky, Marina Tschaika, Ruta Slepetis, Georgia Kollia, Misena Pacius, Ning Huang, Parul Doshi, Jonathan Baden, Massimo Di Nicola,
... survival; tTMB, tissue tumor mutational burden. Citation Format: Michael Schenker, Mauricio Burotto, Martin Richardet, Tudor Ciuleanu, Anthony Goncalves, ...
Tópico(s): Advanced Breast Cancer Therapies
2022 - American Association for Cancer Research | Cancer Research
Michele Maio, Ronnie Shapira‐Frommer, Timothy A. Yap, Tudor‐Eliade Ciuleanu, Henry Gómez, Andrew G. Hill, Iwona Ługowska, Özgür Özyılkan, Karina Vera, Seock‐Ah Im, Anna Kryzhanivska, S. A. Lysenko, Michael Schenker, Salomon M. Stemmer, Sanatan Saraf, Rǎzvan Cristescu, Fan Jin, Alexander Gozman, Miguel Quintela‐Fandino,
... Vera, Seock-Ah Im, Anna Kryzhanivska, Serhii Lysenko, Michael Schenker, Salomon M. Stemmer, Sanatan Saraf, Razvan Cristescu, PhD, ...
Tópico(s): Economic and Financial Impacts of Cancer
2021 - American Association for Cancer Research | Cancer Research
E. Randy Craven, Thomas R. Walters, William C. Christie, Douglas G. Day, Richard A. Lewis, Margot L. Goodkin, Michelle Chen, Veronica Wangsadipura, Michael R. Robinson, Marina Bejanian, Tin Aung, Allen D. Beck, James D. Branch, William C. Christie, Michael Coote, Charles J. Crane, E. Randy Craven, Andrew Crichton, Douglas G. Day, Steven James Day, F. Jane Durcan, Richard Evans, William J. Flynn, Sébastien Gagné, Damien F. Goldberg, Jack V. Greiner, Paul Jeppsen, Delan Jinapriya, C. Starck Johnson, Shimon Kurtz, Richard A. Lewis, Steven L. Mansberger, Joseph R. Martel, Shamira Perera, Michael H. Rotberg, Robert M. Saltzmann, Howard I. Schenker, Michael Tepedino, Maria Imelda R. Yap-Veloso, Harvey S. Uy, Thomas R. Walters,
The objective of this study was to evaluate the safety and intraocular pressure (IOP)-lowering effects over 24 months of biodegradable bimatoprost sustained-release implant (Bimatoprost SR) administration versus topical bimatoprost 0.03% in patients with open-angle glaucoma (OAG).This was a phase I/II, prospective, 24-month, dose-ranging, paired-eye controlled clinical trial. At baseline following washout, adult patients with OAG (N = 75) received Bimatoprost SR (6, 10, 15, or 20 µg) intracamerally in ...
Tópico(s): Corneal surgery and disorders
2019 - Adis, Springer Healthcare | Drugs
Richard A. Lewis, William C. Christie, Douglas G. Day, E. Randy Craven, Thomas R. Walters, Marina Bejanian, Susan S. Lee, Margot L. Goodkin, Jane Zhang, Scott M. Whitcup, Michael R. Robinson, Tin Aung, Allen D. Beck, William C. Christie, Michael Coote, Charles J. Crane, E. Randy Craven, Andrew Crichton, Douglas G. Day, F. Jane Durcan, William J. Flynn, Sébastien Gagné, Damien F. Goldberg, Delan Jinapriya, C. Starck Johnson, Shimon Kurtz, Richard A. Lewis, Steven L. Mansberger, Shamira Perera, Michael H. Rotberg, Robert M. Saltzmann, Howard I. Schenker, Michael Tepedino, Maria Imelda R. Yap-Veloso, Harvey S. Uy, Thomas R. Walters,
PurposeTo evaluate the safety and intraocular pressure (IOP)-lowering effect of a biodegradable bimatoprost sustained-release implant (Bimatoprost SR).DesignPhase I/II, prospective, 24-month, dose-ranging, paired-eye controlled clinical trial.MethodsAt baseline following washout, open-angle glaucoma patients (n = 75) were administered Bimatoprost SR (6 μg, 10 μg, 15 μg, or 20 μg) intracamerally in the study eye; the fellow eye began topical bimatoprost 0.03% once daily. Rescue topical IOP-lowering medication ...
Tópico(s): Ocular Surface and Contact Lens
2016 - Elsevier BV | American Journal of Ophthalmology
... PATH TO ALCOHOLIC LIVER INJURY? Steven Schenker, Steven Schenker Department of Medicine Division of Gastroenterology and Nutrition University of Texas Health Science Center at San Antonio 7703 Floyd Curl Drive San Antonio, Texas 78284-7878Search for more papers by this authorMichael K. Bay, Michael K. Bay Department of Medicine Division of Gastroenterology ... more papers by this author Steven Schenker, Steven Schenker Department of Medicine Division of Gastroenterology and Nutrition University of Texas Health Science Center at San Antonio 7703 Floyd Curl Drive San Antonio, Texas 78284-7878Search for more papers by this authorMichael K. Bay, Michael K. Bay Department of Medicine Division of Gastroenterology ...
Tópico(s): Alcoholism and Thiamine Deficiency
1995 - Wiley | Alcoholism Clinical and Experimental Research
Produção Nacional
Revisado por pares
David P. Carbone, Tudor‐Eliade Ciuleanu, Michael Schenker, Manuel Cobo, Stéphanie Bordenave-Juchereau, Óscar Juan, J. Menezes, Niels Reinmuth, Eduardo Richardet, Ying Cheng, Hideaki Mizutani, Luis Paz‐Ares, Shun Lu, Thomas John, Xiaoqing Zhang, Nan Hu, David Balli, Vipul Baxi, Jaclyn Neely, Martin Reck,
LBA9023 Background: In CheckMate 9LA (NCT03215706), 1L N + I + C demonstrated durable survival benefit in pts with mNSCLC vs C alone. Here, we report updated efficacy and safety with a 4-y minimum (min) follow-up (f/u) as well as exploratory analyses of efficacy by THS, a known prognostic indicator for NSCLC. Methods: Adults with stage IV/recurrent NSCLC (no known sensitizing EGFR/ALK alterations) and ECOG PS ≤ 1 were randomized 1:1 to N 360 mg Q3W + I 1 mg/kg Q6W + 2 cycles of C (n = 361) or 4 cycles of C alone ( ...
Tópico(s): Lung Cancer Treatments and Mutations
2023 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Gerard P. Slobogean, Sheila Sprague, Jeffrey Wells, Mohit Bhandari, Jean-Claude D’Alleyrand, Anthony Harris, Daniel C. Mullins, Lehana Thabane, Amber Wood, Gregory J. Della Rocca, Joan Hebden, Kyle J. Jeray, Lucas S. Marchand, Lyndsay M. O’Hara, Robert Zura, Michael J. Gardner, Jenna Blasman, Jonah Davies, Stephen Y. Liang, Monica Taljaard, P.J. Devereaux, Gordon Guyatt, Debra Marvel, Jana Palmer, Jeff Friedrich, Nathan N. O’Hara, Ms. Frances Grissom, Ida Leah Gitajn, Saam Morshed, Robert V. O’Toole, Brad Petrisor, Megan Camara, Franca Mossuto, Manjari Joshi, Justin Fowler, Jessica C. Rivera, Max Talbot, Shannon Dodds, Alisha Garibaldi, Silvia Li, Uyen Nguyen, David Pogorzelski, Alejandra Rojas, Taryn Scott, Gina Del Fabbro, Olivia P. Szasz, Diane Heels‐Ansdell, Paula McKay, Andrea Howe, Joshua Rudnicki, Haley K. Demyanovich, Kelly Little, Eric Kettering, Diamond Hale, Andrew Eglseder, Aaron J. Johnson, Christopher G. Langhammer, Christopher Lebrun, Theodore Mandon, Jason W. Nascone, Ebrahim Paryavi, Raymond A. Pensy, Andrew N. Pollak, Marcus F. Sciadini, Yasmin Degano, Haley K. Demyanovich, Katherine Joseph, Herman Johal, Bill Ristevski, Dale Williams, Matthew Denkers, Krishan Rajaratnam, Jamal Al-Asiri, Jordan Leonard, Francesc Marcano-Fernández, Jodi Gallant, Federico Pérsico, Marko Gjorgjievski, Roman M. Natoli, Greg E. Gaski, Todd O. McKinley, Walter W. Virkus, Anthony T. Sorkin, J. Szatkowski, Joseph R. Baele, Brian Mullis, Lauren C. Hill, Andrea Hudgins, Patrick M. Osborn, Sarah N. Pierrie, Eric Martinez, Joseph Kimmel, John D. Adams, Michael L. Beckish, Christopher C. Bray, Timothy R. Brown, Andrew W. Cross, Timothy Dew, Gregory K. Faucher, Richard W. Gurich, David E. Lazarus, S. John Millon, M. Jason Palmer, Scott E. Porter, Thomas M. Schaller, Michael S. Sridhar, John Sanders, L. Edwin Rudisill, Michael J. Garitty, Andrew S. Poole, Michael L. Sims, Clark M. Walker, Robert Carlisle, Erin Adams-Hofer, Brandon S. Huggins, Michael D. Hunter, W. A. Marshall, Shea Bielby Ray, Cory D. Smith, Kyle M. Altman, Julia C. Bedard, Markus F. Loeffler, Erin R. Pichiotino, Austin A. Cole, Ethan J. Maltz, Wesley Parker, T. Bennett Ramsey, Alex Burnikel, Michael Colello, Russel Stewart, Jeremy Wise, Stephanie L. Tanner, Rebecca G. Snider, Christine E. Townsend, Kayla H. Pham, Abigail Martin, Emily Robertson, Utku Kandemir, Meir Mormor, Amir Matityahu, R. Trigg McClellan, Eric Meinberg, Theodore Miclau, David Shearer, Paul Toogood, Anthony Ding, Erin Donohue, Tigist Belaye, Eleni Berhaneselase, Alexandra Paúl, Kartik Garg, Joshua L. Gary, Stephanie J. Warner, John W. Munz, Andrew M. Choo, Timothy S. Schor, Milton L. Chip Routt, Mayank Rao, Guillermo Pechero, Adam S. Miller, Jennifer E. Hagen, Matthew Patrick, Kalia Sadasivan, Chris Koenig, Daniel P. Bailey, Daniel Wentworth, Chi Van, Justin T. Schwartz, Clifford B. Jones, Jessica Watson, Michael D. McKee, Niloofar Dehghan, A Karim, Michael Talerico, Debra L. Sietsema, Alyse Williams, Tayler Dykes, William T. Obremsky, A. Alex Jahangir, Manish K. Sethi, Robert Boyce, Daniel J. Stinner, Karen Trochez, Andrés Rodríguez, Vamshi Gajari, Olivia M. Knoll, Charles Pritchett, Christina Boulton, Jason Lowe, Jason R. Wild, John T. Ruth, Michel Taylor, Andrea Seach, Sabina Saeed, Hunter Culbert, Alejandro Francisco‐Cruz, Thomas R. Knapp, Colin Hurkett, Maya Lowney, Michael J. Prayson, Indresh Venkatarayappa, Brandon Horne, Jennifer Jerele, Linda Clark, Kammie Snure, Mara L. Schenker, Michael Maceroli, W. Michael Reisman, Clifton Meals, Thomas J. Moore, Brent Wise, Diane Payne, Christopher K. Sadlack, Erika Ortega, Nicholas M. Romeo, Heather A. Vallier, Mary A. Breslin, Joanne Fraifogl, Eleanor S. Wilson, Leanne K. Wadenpfuhl, Darius G. Viskontas, Kelly Apostle, Dory Boyer, Farhas O. Moola, Bertrand H. Perey, Trevor Stone, H. Michael Lemke, Mauri Zomar, Ella Spicer, Chen “Brenda” Fan, Krysten Payne, Kevin D. Phelps, Michael J. Bosse, Madhav A. Karunakar, Laurence B. Kempton, Stephen H. Sims, Joseph R. Hsu, Rachel B. Seymour, Christine Churchill, Claire Bartel, Robert Miles Mayberry, Mary Brownrigg, K. Brown, Ada Mayfield, Robert A. Hymes, Cary C. Schwartzbach, Jeff E. Schulman, Arjan Malekzadeh, Michael A. Holzman, Lolita Ramsey, James S. Ahn, Farhanaz Panjshiri, Sharon Haaser, Jaslynn Cuff, Holly Pilson, Eben A. Carroll, Jason J. Halvorson, Sharon Babcock, J. Brett Goodman, Martha B. Holden, Debra Bullard, Wendy R. Williams, Thomas F. Higgins, Justin M. Haller, David L. Rothberg, Ashley Neese, Mark Russell, Marcus P. Coe, Kevin Dwyer, Devin S. Mullin, Cliff Reilly, Peter DePalo, Marilyn Heng, Mitchel B. Harris, R. M. Smith, David W. Lhowe, John G. Esposito, Mira Bansal, Patrick F. Bergin, George V. Russell, Matthew L. Graves, John Morellato, LaRita C. Jones, Heather K. Champion, Leslie N. Johnson, Susan Q. Allbritton, Samir Mehta, Derek Donehan, Jaimo Ahn, Annamarie D. Horan, K. Reed Clark, Mary Dooley, Justina Toma, Ashley Kuczinski, David A. Potter, Robert VanDemark,
The risk of developing a surgical site infection after extremity fracture repair is nearly 5 times greater than in most elective orthopedic surgical procedures. For all surgical procedures, it is standard practice to prepare the operative site with an antiseptic solution; however, there is limited evidence to guide the choice of solution used for orthopedic fracture repair.To compare the effectiveness of iodophor vs chlorhexidine solutions to reduce surgical site infections and unplanned fracture- ...
American Medical Association
Produção Nacional
Revisado por pares
Daniel Shao-Weng Tan, Enriqueta Felip, Gilberto de Castro, Benjamin Solomon, Alastair Greystoke, Byoungchul Cho, Manuel Cobo, Tae Min Kim, Sandip Ganguly, Enric Carcereny, Luis Paz‐Ares, Jaafar Bennouna, Marina Chiara Garassino, Michael Schenker, Sang‐We Kim, Bijoyesh Mookerje, Vanessa Q. Passos, Stéphanie Deudon, Bharani Dharan, Yuanbo Song, Rafael Caparica, Bruce E. Johnson,
... Carcereny, Luis Paz-Ares, Jaafar Bennouna, Marina Garassino, Michael Schenker, Sang-We Kim, Bijoyesh Mookerje, Vanessa Q. Passos, ...
Tópico(s): Lung Cancer Diagnosis and Treatment
2022 - American Association for Cancer Research | Cancer Research
Diana Toubassi, Carly Schenker, Michael Roberts, Milena Forte,
Trainee distress and burnout continue to be serious concerns for educational programs in medicine, prompting the implementation of numerous interventions. Although an expansive body of literature suggests that the experience of meaning at work is critical to professional wellbeing, relatively little attention has been paid to how this might be leveraged in the educational milieu. We propose that professional identity formation (PIF), the process by which trainees come to not only attain competence, ...
Tópico(s): Healthcare professionals’ stress and burnout
2022 - Springer Science+Business Media | Advances in Health Sciences Education
Clary J. Foote, Paul Tornetta, Aleksi Reito, Khalid Al-Hourani, Mara L. Schenker, Michael J. Bosse, Chad P. Coles, Anthony Bozzo, Andrew Furey, Ross Leighton,
Update This article was updated on February 9, 2021, because of a previous error. On page 269, in the Note at the end of the article, the surname that had read “Merner” now reads “Mener.” An erratum has been published: J Bone Joint Surg Am. 2021 Mar 17;103(6):e25. Background: Open fractures are one of the leading causes of disability worldwide. The threshold time to debridement that reduces the infection rate is unclear. Methods: We searched all available databases to identify observational studies ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2020 - Wolters Kluwer | Journal of Bone and Joint Surgery
Hanno Schenker, Michael Wild, Björn Rath, Markus Tingart, Arne Driessen, Valentin Quack, Marcel Betsch,
Tópico(s): Osteoarthritis Treatment and Mechanisms
2017 - Springer Science+Business Media | Der Orthopäde
Robert E. Becker, Urs Braun, Adam J. Schwarz, Natalia Gass, Janina I. Schweiger, Wolfgang Weber‐Fahr, Esther Schenker, Michael Spedding, Christian Clemm von Hohenberg, Céline Risterucci, Zhenxiang Zang, O. Grimm, Heike Tost, Alexander Sartorius, Andreas Meyer‐Lindenberg,
Abstract Species-conserved (intermediate) phenotypes that can be quantified and compared across species offer important advantages for translational research and drug discovery. Here, we investigate the utility of network science methods to assess the pharmacological alterations of the large-scale architecture of brain networks in rats and humans. In a double-blind, placebo-controlled, cross-over study in humans and a placebo-controlled two-group study in rats, we demonstrate that the application ...
Tópico(s): Tryptophan and brain disorders
2016 - Springer Nature | Translational Psychiatry
Anushree Tripathi, Esther Schenker, Michael Spedding, Thérèse M. Jay,
Tópico(s): Stress Responses and Cortisol
2015 - Springer Science+Business Media | Brain Structure and Function
O. Grimm, Natalia Gass, Wolfgang Weber‐Fahr, Alexander Sartorius, Esther Schenker, Michael Spedding, Céline Risterucci, Janina I. Schweiger, Andreas Böhringer, Zhenxiang Zang, Heike Tost, Adam J. Schwarz, Andreas Meyer‐Lindenberg,
Tópico(s): Tryptophan and brain disorders
2015 - Springer Science+Business Media | Psychopharmacology
Antonio Baici, Patricia Schenker, Michael P. Wachter, Peter Rüedi,
Abstract magnified image A systematic survey of the acetylcholine‐mimetic 2,4‐dioxa‐3‐phosphadecalins as irreversible inhibitors of acetylcholinesterase revealed hitherto overlooked properties as far as the kinetic mechanisms of interaction are concerned. As a support to past and future work in this field, we describe the kinetics of eight reaction schemes that may be found in irreversible enzyme modification and compare them with two mechanism of reversible, slow‐binding inhibition. The relevant ...
Tópico(s): Organophosphorus compounds synthesis
2009 - Wiley | Chemistry & Biodiversity