Stella Lukas Yani, Michael Keller, Franz Leonard Melzer, Birgit Weinberger, Luca Pangrazzi, Sieghart Sopper, Klemens Trieb, Monia Lobina, Valeria Orrù, Edoardo Fiorillo, Francesco Cucca, Beatrix Grubeck‐Loebenstein,
CD4+ regulatory T cells have been intensively studied during aging, but little is still known about age-related changes of other regulatory T cell subsets. It was therefore the goal of the present study to analyze CD8+HLADR+ T cells in old age, a cell population reported to have suppressive activity and to be connected to specific genetic variants. We demonstrate a strong increase in the number of CD8+HLADR+ T cells with age in a cohort of female Sardinians as well as in elderly male and female ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2018 - Frontiers Media | Frontiers in Immunology
YANI DUAN, Michael D. Webb, Yalin Zhang,
The leafhopper tribe Stenometopiini is revised from China. Two genera are included: Hodoedocus Jacobi with two species and Stirellus Osborn & Ball with thirteen species of which four are new: S. daii sp. nov., S. multipunctatus sp. nov., S. neospeciosus sp. nov., and S. translucidus sp. nov. S. yeongnamensis (Kwon & Lee) is newly recorded for China. Five new synonyms are proposed: Viridomarus brevialatus Xing et al. and Viridomarus laticellus Xing et al. as junior synonyms of S. capitatus (Distant); Aconura ...
Tópico(s): Fossil Insects in Amber
2016 - Q15088586 | Zootaxa
Nam Q. Pham, Seonju Marincowitz, ShuaiFei Chen, Yani Yaparudin, Michael J. Wingfield,
Tópico(s): Plant Pathogenic Bacteria Studies
2022 - Springer Science+Business Media | Mycological Progress
Marge Coahran, Loretta M. Hillier, Lisa Van Bussel, Edward E. Black, Rebekah Churchyard, Iris Gutmanis, Yani Ioannou, Kathleen Michael, Tom Ross, Alex Mihailidis,
RÉSUMÉ Les personnes âgées hospitalisées présentent un haut risque de chute. Le système HELPER est un système de détection des chutes fixé au plafond qui envoie une alerte à un téléphone intelligent lorsqu’une chute est détectée. Cet article décrit la performance du système HELPER, qui a été testé dans un projet pilote mené dans un centre de santé mentale gériatrique. La précision du système pour la détection des chutes a été comparée aux données de l’hôpital liées à la documentation des chutes. ...
Tópico(s): Non-Invasive Vital Sign Monitoring
2018 - Cambridge University Press | Canadian Journal on Aging / La Revue canadienne du vieillissement
M. R. B. A. Rauf, Alistair R. McTaggart, Seonju Marincowitz, Irene Barnes, Yani Japarudin, Michael J. Wingfield,
Tópico(s): Plant and Fungal Interactions Research
2019 - Springer Science+Business Media | Australasian Plant Pathology
Jun‐Yuan Ji, Wayne Miles, Michael Korenjak, Yani Zheng, Nicholas J. Dyson,
Abstract The E2F transcription factors are important regulators of the cell cycle whose function is commonly misregulated in cancer. To identify novel regulators of E2F1 activity in vivo, we used Drosophila to conduct genetic screens. For this, we generated transgenic lines that allow the tissue-specific depletion of dE2F1 by RNAi. Expression of these transgenes using Gal4 drivers in the eyes and wings generated reliable and modifiable phenotypes. We then conducted genetic screens testing the capacity ...
Tópico(s): Cancer-related gene regulation
2012 - Genetics Society of America | G3 Genes Genomes Genetics
YANI DUAN, Chris H. Dietrich, Michael D. Webb, Yalin Zhang,
Two new genera and three new species of the leafhopper tribe Deltocephalini are described from Thailand, viz., Loeia Duan gen. n. with L. tamtipi Duan sp. n. as type species, Phetchabunia Duan gen. n. with P. janteabi Duan sp. n. as type species, and Maiestas subsirii Duan sp. n.. Five new country records for Thailand are also given, viz. Deltocephalus vulgaris Dash & Viraktamath, Maiestas dinghuensis Zhang & Duan, Maiestas scripta (Distant), Paramesodes sp., and Polyamia acicularis Dai, Xing & Li.
Tópico(s): Orthoptera Research and Taxonomy
2017 - Q15088586 | Zootaxa
Huiyan Ma, Giske Ursin, Xinxin Xu, Eunjung Lee, Kayo Togawa, Kathleen E. Malone, Polly A. Marchbanks, Jill A. McDonald, Michael S. Simon, Suzanne G. Folger, Yani Lu, Jane Sullivan‐Halley, Dennis Deapen, Michael F. Press, Leslie Bernstein,
Although it has been well-documented that obesity is associated with decreased risk of premenopausal breast cancer and increased risk of postmenopausal breast cancer, it is unclear whether these associations differ among breast cancer subtypes defined by the tumor protein expression status of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). We evaluated the associations of body mass index (BMI) at age 18 years and recent BMI in relation to risk ...
Tópico(s): Metastasis and carcinoma case studies
2018 - BioMed Central | Breast Cancer Research
Renata Conger, Yani Chen, Silvia Fornaciari, Carmen Faso, Michael Held, Luciana Renna, Federica Brandizzí,
Eukaryotic cells use COPII-coated carriers for endoplasmic reticulum (ER)-to-Golgi protein transport. Selective cargo capture into ER-derived carriers is largely driven by the SEC24 component of the COPII coat. The Arabidopsis genome encodes three AtSEC24 genes with overlapping expression profiles but it is yet to be established whether the AtSEC24 proteins have overlapping roles in plant growth and development. Taking advantage of Arabidopsis thaliana as a model plant system for studying gene function ...
Tópico(s): Photosynthetic Processes and Mechanisms
2011 - Oxford University Press | Journal of Experimental Botany
Bismillah Shah, Hassan Naveed, Michael D. Webb, YANI DUAN,
The grassland leafhopper genus Maiestas Distant is reviewed from Pakistan with the description and illustrations of one new species, Maiestas sinuata Shah Duan sp. n., and two new records, i.e., Maiestas maculata n. rec. and Maiestas trispinosa n. rec. A checklist of the known species of Maiestas from Pakistan is also given together with a key for their separation (males).
Tópico(s): Hymenoptera taxonomy and phylogeny
2021 - Q15088586 | Zootaxa
Djordje Grujić, Gwladys Govin, Laurie Barrier, Bodo Bookhagen, Isabelle Coutand, Beth Cowan, Michael T. Hren, Yani Najman,
Abstract We measure the oxygen and hydrogen stable isotope composition of authigenic clays from Himalayan foreland sediments (Siwalik Group), and from present day small stream waters in eastern Bhutan to explore the impact of uplift of the Shillong Plateau on rain shadow formation over the Himalayan foothills. Stable isotope data from authigenic clay minerals (<2 μm) suggest the presence of three paleoclimatic periods during deposition of the Siwalik Group, between ∼7 and ∼1 Ma. The mean δ 18 O value ...
Tópico(s): Hydrocarbon exploration and reservoir analysis
2018 - Wiley | Geochemistry Geophysics Geosystems
Gabrielle R. Budziszewski, Yani Zhao, Cathy J. Spangler, Katarzyna M. Kedziora, Michael R. Williams, Dalal N. Azzam, Aleksandra Skrajna, Yuka Koyama, Andrew P. Cesmat, Holly C. Simmons, Eyla C. Arteaga, Joshua D. Strauss, Dmitri Kireev, Robert K. McGinty,
A key role of chromatin kinases is to phosphorylate histone tails during mitosis to spatiotemporally regulate cell division. Vaccinia-related kinase 1 (VRK1) is a serine-threonine kinase that phosphorylates histone H3 threonine 3 (H3T3) along with other chromatin-based targets. While structural studies have defined how several classes of histone-modifying enzymes bind to and function on nucleosomes, the mechanism of chromatin engagement by kinases is largely unclear. Here, we paired cryo-electron ...
Tópico(s): Virus-based gene therapy research
2022 - Oxford University Press | Nucleic Acids Research
Jeremy Brawner, Yani Japarudin, Mahadir Lapammu, Redzuan Rauf, D. I. Boden, Michael J. Wingfield,
AbstractA dramatic rise in the incidence of a serious canker and wilt disease of Acacia mangium has led to the replacement of thousands of hectares of plantation forests in eastern Sabah. A disease screening program was initiated to evaluate levels of disease resistance and tolerance to the causative fungus, Ceratocystis acaciivora, in an A. mangium breeding population. Resistance was evaluated as the presence or absence of external symptoms in two open-pollinated progeny trials. In addition, tolerance ...
Tópico(s): Plant and Fungal Interactions Research
2015 - Taylor & Francis | Southern Forests a Journal of Forest Science
Yani Najman, Stuart D. Burley, Alex Copley, Michael J. Kelly, Kaushal Pander, Premanand Mishra,
Abstract A well‐developed late Eocene to Miocene unconformity, termed the base Miocene unconformity (BMU), is found throughout the intraplate basins of northwestern India and has previously been ascribed to Himalayan tectonics. This hypothesis is investigated by first describing the nature and age of the BMU in the northwest (NW) Indian intraplate basins and then reconstructing the location of the BMU relative to the Himalayan deformation front at the time it formed. We suggest that formation of the ...
Tópico(s): Geological and Geochemical Analysis
2018 - Wiley | Tectonics
Huiyan Ma, Xinxin Xu, Giske Ursin, Michael S. Simon, Polly A. Marchbanks, Kathleen E. Malone, Yani Lu, Jill A. McDonald, Suzanne G. Folger, Linda K. Weiss, Jane Sullivan‐Halley, Dennis Deapen, Michael F. Press, Leslie Bernstein,
Abstract Convincing epidemiologic evidence indicates that physical activity is inversely associated with breast cancer risk. Whether this association varies by the tumor protein expression status of the estrogen receptor ( ER ), progesterone receptor ( PR ), human epidermal growth factor receptor 2 ( HER 2), or p53 is unclear. We evaluated the effects of recreational physical activity on risk of invasive breast cancer classified by the four biomarkers, fitting multivariable unconditional logistic regression ...
Tópico(s): Physical Activity and Health
2015 - Wiley | Cancer Medicine
Yani Zhou, Sarah L. Wynia‐Smith, Shalise M. Couvertier, Kelsey Kalous, Michael A. Marletta, Brian C. Smith, Eranthie Weerapana,
S-Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins, thereby regulating diverse protein functions. Quantitative proteomic methods are necessary to establish which cysteine residues are most sensitive to GSNO-mediated transnitrosation. Here, a competitive cysteine-reactivity profiling strategy was implemented to quantitatively measure the sensitivity of >600 cysteine residues to transnitrosation by GSNO. This platform identified ...
Tópico(s): Adenosine and Purinergic Signaling
2016 - Elsevier BV | Cell chemical biology
Huiyan Ma, Giske Ursin, Xinxin Xu, Eunjung Lee, Kayo Togawa, Lei Duan, Yani Lu, Kathleen E. Malone, Polly A. Marchbanks, Jill A. McDonald, Michael S. Simon, Suzanne G. Folger, Jane Sullivan‐Halley, Dennis Deapen, Michael F. Press, Leslie Bernstein,
Early age at menarche, nulliparity, late age at first completed pregnancy, and never having breastfed, are established breast cancer risk factors. However, among breast cancer subtypes, it remains unclear whether all of these are risk factors for triple-negative breast cancer (TNBC). We evaluated the associations of these reproductive factors with TNBC, in 2658 patients with breast cancer (including 554 with TNBC) and 2448 controls aged 20–64 years, who participated in one of the three population- ...
Tópico(s): Cancer-related Molecular Pathways
2017 - BioMed Central | Breast Cancer Research
Euna Yoo, Christopher J. Schulze, Barbara H. Stokes, Ouma Onguka, Tomas Yeo, Sachel Mok, Nina F. Gnädig, Yani Zhou, Kenji L. Kurita, Ian T. Foe, Stephanie M. Terrell, Michael J. Boucher, Piotr Cieplak, Krittikorn Kümpornsin, Lee M, Roger G. Linington, Jonathan Z. Long, Anne‐Catrin Uhlemann, Eranthie Weerapana, David A. Fidock, Matthew Bogyo,
Salinipostin A (Sal A) is a potent antiplasmodial marine natural product with an undefined mechanism of action. Using a Sal A-derived activity-based probe, we identify its targets in the Plasmodium falciparum parasite. All of the identified proteins contain α/β serine hydrolase domains and several are essential for parasite growth. One of the essential targets displays a high degree of homology to human monoacylglycerol lipase (MAGL) and is able to process lipid esters including a MAGL acylglyceride ...
Tópico(s): Synthesis and Catalytic Reactions
2020 - Elsevier BV | Cell chemical biology
Van Vo, Anthony Harrington, Ching-Lan Chang, Hayley Baker, Michael A. Moshi, Nabih Ghani, Jose Yani Itorralba, Richard Tillett, Elizabeth Dahlmann, Natnael Basazinew, Richard Gu, Tiffany D. Familara, Sage Boss, Fritz Vanderford, Moonis Ghani, Austin J. Tang, Alice Matthews, Katerina Papp, Eakalak Khan, Carolina Koutras, Horng-Yuan Kan, Cassius Lockett, Daniel Gerrity, Edwin C. Oh,
Real-time surveillance of infectious diseases at schools or in communities is often hampered by delays in reporting due to resource limitations and infrastructure issues. By incorporating quantitative PCR and genome sequencing, wastewater surveillance has been an effective complement to public health surveillance at the community and building-scale for pathogens such as poliovirus, SARS-CoV-2, and even the monkeypox virus. In this study, we asked whether wastewater surveillance programs at elementary ...
Tópico(s): Viral gastroenteritis research and epidemiology
2023 - Elsevier BV | The Science of The Total Environment
Huiyan Ma, Yani Lu, Polly A. Marchbanks, Suzanne G. Folger, Brian L. Strom, Jill A. McDonald, Michael S. Simon, Linda K. Weiss, Kathleen E. Malone, Ronald T. Burkman, Jane Sullivan‐Halley, Dennis Deapen, Michael F. Press, Leslie Bernstein,
Abstract Introduction The association of breast cancer patients’ mortality with estrogen receptor (ER) status (ER + versus ER-) has been well studied. However, little attention has been paid to the relationship between the quantitative measures of ER expression and mortality. Methods We evaluated the association between semi-quantitative, immunohistochemical staining of ER in formalin-fixed paraffin-embedded breast carcinomas and breast cancer-specific mortality risk in an observational cohort of invasive ...
Tópico(s): Global Cancer Incidence and Screening
2013 - BioMed Central | Breast Cancer Research
Produção Nacional
Revisado por pares
Saura R. Silva, Danillo Oliveira Alvarenga, Yani Aranguren, Helen Alves Penha, Camila C. Fernandes, Daniel Guariz Pinheiro, Marcos T. Oliveira, Todd P. Michael, Vitor F. O. Miranda, Alessandro M. Varani,
The carnivorous plants of the family Lentibulariaceae have attained recent attention not only because of their interesting lifestyle, but also because of their dynamic nuclear genome size. Lentibulariaceae genomes span an order of magnitude and include species with the smallest genomes in angiosperms, making them a powerful system to study the mechanisms of genome expansion and contraction. However, little is known about mitochondrial DNA (mtDNA) sequences of this family, and the evolutionary forces ...
Tópico(s): Plant Diversity and Evolution
2017 - Public Library of Science | PLoS ONE
Yani Lu, Huiyan Ma, Kathleen E. Malone, Sandra A. Norman, Jane Sullivan‐Halley, Brian L. Strom, Michael S. Simon, Polly A. Marchbanks, Jill A. McDonald, Dee W. West, Katherine D. Henderson, Dennis Deapen, Giske Ursin, Leslie Bernstein,
Abstract Background: Oral contraceptives (OC) are widely used in the United States. Although the relation between OC use and breast cancer incidence has been widely studied, the few studies examining associations between OC use prior to breast cancer diagnosis and survival are inconsistent. Methods: Women with invasive breast cancer participating in the Women's Contraceptive and Reproductive Experiences (CARE) Study, a population-based case–control study (4565 women ages 35–64 years), and the California ...
Tópico(s): Cancer Risks and Factors
2011 - American Association for Cancer Research | Cancer Epidemiology Biomarkers & Prevention
Produção Nacional
Revisado por pares
Saura R. Silva, Yani Aranguren, Helen Alves Penha, Daniel Guariz Pinheiro, Camila C. Fernandes, Vitor F. O. Miranda, Todd P. Michael, Alessandro M. Varani,
Lentibulariaceae is the richest family of carnivorous plants spanning three genera including Pinguicula, Genlisea, and Utricularia. Utricularia is globally distributed, and, unlike Pinguicula and Genlisea, has both aquatic and terrestrial forms. In this study we present the analysis of the chloroplast (cp) genome of the terrestrial Utricularia reniformis. U. reniformis has a standard cp genome of 139,725bp, encoding a gene repertoire similar to essentially all photosynthetic organisms. However, an ...
Tópico(s): Protist diversity and phylogeny
2016 - Public Library of Science | PLoS ONE
Michael Duvall, John W.F. Waldron, Laurent Godin, Yani Najman,
Significance The Himalayan mountain belt results from continuing convergence between the Indian Plate and Asia. Damaging earthquakes occur on major thrust faults north of the Main Frontal Thrust (MFT). To the south, the Ganga foreland basin is typically described as undeformed. We show that active thrust and strike-slip faults, with accumulated slip up to ∼100 m, pass under the trace of the MFT into the foreland basin in eastern Nepal, leading to propagation of deformation at least ∼37 km into the ...
Tópico(s): High-pressure geophysics and materials
2020 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Shona C. Moore, Rebekah Penrice-Randal, Muhannad Alruwaili, Nadine Randle, Stuart D. Armstrong, Catherine Hartley, Sam Haldenby, Xiaofeng Dong, Abdulrahman Alrezaihi, Mai Almsaud, Eleanor G. Bentley, Jordan J. Clark, Isabel García-Dorival, Paul Gilmore, Ximeng Han, Benjamin Jones, Lisa Luu, Parul Sharma, Ghada T. Shawli, Yani Sun, Qin Zhao, Steven T. Pullan, Daniel Carter, Kevin R. Bewley, Jake Dunning, En‐Min Zhou, Tom Solomon, Michael Beadsworth, James Cruise, Derrick W. Crook, David A. Matthews, Andrew D. Davidson, Zana H. Mahmood, Waleed Aljabr, Julian Druce, Richard Vipond, Lisa F. P. Ng, Laurent Rénia, Peter Openshaw, J. Kenneth Baillie, Miles W. Carroll, James P. Stewart, Alistair C. Darby, Malcolm G. Semple, Lance Turtle, Julian A. Hiscox,
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). Sequencing the viral genome as the outbreak progresses is important, particularly in the identification of emerging isolates with different pathogenic potential and to identify whether nucleotide changes in the genome will impair clinical diagnostic tools such as real-time PCR assays. Although single nucleotide polymorphisms and point mutations occur during the replication of ...
Tópico(s): Animal Virus Infections Studies
2020 - Multidisciplinary Digital Publishing Institute | Viruses
Christian France‐Lanord, V. Spieß, Adam Klaus, Rishi R. Adhikari, Swostik K. Adhikari, Jang J. Bahk, Alan T. Baxter, Jarrett W. Cruz, Satyabrata Das, Petra Dekens, Wânia Duleba, Lyndsey Fox, Αlbert Galy, Valier Galy, J. Ge, James D. Gleason, Babu Gyawali, Pascale Huyghe, Guodong Jia, Hendrik Lantzsch, M. C. Manoj, Y. Martos Martin, Laure Meynadier, Yani Najman, A. Nakajima, Camilo Ponton, Brendan T. Reilly, Kimberly G. Rogers, J.F. Savian, T. Schwenk, Peter A. Selkin, Michael E Weber, Trevor Williams, Kohki Yoshida,
Tópico(s): Hydrocarbon exploration and reservoir analysis
2016 - | Proceedings of the International Ocean Discovery Program. Expedition reports
Christian France‐Lanord, V. Spieß, Adam Klaus, Rishi R. Adhikari, Swostik K. Adhikari, Jang J. Bahk, Alan T. Baxter, Jarrett W. Cruz, Satyabrata Das, Petra Dekens, Wânia Duleba, Lyndsey Fox, Αlbert Galy, Valier Galy, J. Ge, James D. Gleason, Babu Gyawali, Pascale Huyghe, Guodong Jia, Hendrik Lantzsch, M. C. Manoj, Y. Martos Martin, Laure Meynadier, Yani Najman, A. Nakajima, Camilo Ponton, Brendan T. Reilly, Kimberly G. Rogers, J.F. Savian, T. Schwenk, Peter A. Selkin, Michael E Weber, Trevor Williams, Kohki Yoshida,
Tópico(s): Geological and Geochemical Analysis
2016 - | Proceedings of the International Ocean Discovery Program. Expedition reports
Christian France‐Lanord, V. Spieß, Adam Klaus, Rishi R. Adhikari, Swostik K. Adhikari, Jang J. Bahk, Alan T. Baxter, Jarrett W. Cruz, Satyabrata Das, Petra Dekens, Wânia Duleba, Lyndsey Fox, Αlbert Galy, Valier Galy, J. Ge, James D. Gleason, Babu Gyawali, Pascale Huyghe, Guodong Jia, Hendrik Lantzsch, M. C. Manoj, Y. Martos Martin, Laure Meynadier, Yani Najman, A. Nakajima, Camilo Ponton, Brendan T. Reilly, Kimberly G. Rogers, J.F. Savian, T. Schwenk, Peter A. Selkin, Michael E Weber, Trevor Williams, Kohki Yoshida,
Tópico(s): Methane Hydrates and Related Phenomena
2016 - | Proceedings of the International Ocean Discovery Program. Expedition reports
Christian France‐Lanord, V. Spieß, T. Schwenk, Adam Klaus, Rishi R. Adhikari, Swostik K. Adhikari, Jang J. Bahk, Alan T. Baxter, Jarrett W. Cruz, Satyabrata Das, Petra Dekens, Wânia Duleba, Lyndsey Fox, Αlbert Galy, Valier Galy, J. Ge, James D. Gleason, Babu Gyawali, Pascale Huyghe, Guodong Jia, Hendrik Lantzsch, M. C. Manoj, Y. Martos Martin, Laure Meynadier, Yani Najman, A. Nakajima, Camilo Ponton, Brendan T. Reilly, Kimberly G. Rogers, J.F. Savian, Peter A. Selkin, Michael E Weber, Trevor Williams, Kohki Yoshida,
International Ocean Discovery Expedition 354 to 8°N in the Bay of Bengal drilled a seven site, 320 km long transect across the Bengal Fan.Three deep-penetration and an additional four shallow holes give a spatial overview of the primarily turbiditic depositional system that comprises the Bengal deep-sea fan.Sediments originate from Himalayan rivers, documenting terrestrial changes of Himalayan erosion and weathering, and are transported through a delta and shelf canyon, supplying turbidity currents ...
Tópico(s): Geological formations and processes
2015 - | Preliminary report
Produção Nacional
Revisado por pares
Yani Aranguren, Alessandro M. Varani, Todd P. Michael, Vitor F. O. Miranda,
Genlisea aurea A.St.-Hil. is a carnivorous plant endemic species to Brazil in the Lentibulariaceae family. Very few studies have addressed the genetic structure and conservation status of G. aurea and the Lentibulariaceae. Microsatellites markers are advantageous tools that can be employed to predict the vulnerability of Lentibulariaceae species. Therefore, the development of molecular markers focusing the population analyses of Genlisea for future genetic studies and conservation actions are essential. ...
Tópico(s): Plant Parasitism and Resistance
2017 - Springer Nature | Molecular Biology Reports