... 1–18.https://doi.org/10.1007/BF01581894Rodolphe Dos Santos Ferreira, Philippe Michel Keynes' Aggregate Supply Function and the Principle of ...
Tópico(s): Corporate Taxation and Avoidance
1932 - University of Chicago Press | Journal of Political Economy
Produção Nacional
Revisado por pares
Ana Cláudia F. Amaral, Aline de Souza Ramos, Márcia Reis Pena, José Luiz P. Ferreira, Jean Michel dos Santos Menezes, Geraldo José Nascimento de Vasconcelos, Néliton Marques da Sílva, Jefferson Rocha de Andrade Silva,
To evaluate the acaricidal activity of the essential oil obtained from roots of Derris floribunda (D. floribunda) (Miq.) Benth, and its main constituent nerolidol against the Mexican mite Tetranychus mexicanus (T. mexicanus) (McGregor). The essential oil from the roots of D. floribunda collected in the Amazon region (Brazil) was obtained by hydrodistillation. Its chemical composition was determined by GC–MS analysis. The acaricidal activities of this essential oil and nerolidol, were evaluated by recording ...
Tópico(s): Insect-Plant Interactions and Control
2017 - Medknow | Asian Pacific Journal of Tropical Biomedicine
Produção Nacional
Revisado por pares
Maycon Júnior Ferreira, Michel Pablo dos Santos Ferreira Silva, Danielle da Silva Dias, Nathália Bernardes, Maria Cláudia Irigoyen, Kátia De Angelis,
Objective This study aimed to evaluate whether exercise training could contribute to a better modulation of the neurohumoral mechanisms linked to the pathophysiology of arterial hypertension (AH) in postmenopausal hypertensive rats treated with hydrochlorothiazide (HCTZ). Methods Female spontaneously hypertensive rats (SHR) (150−200g, 90 days old) were distributed into 5 hypertensive groups (n = 7–8 rats/group): control (C), ovariectomized (O), ovariectomized treated with HCTZ (OH), ovariectomized submitted ...
Tópico(s): Circadian rhythm and melatonin
2023 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Igor Frederico da Silveira Ramos, Liana Moreira Magalhães, Cláudia Pessoa, Paulo Michel Pinheiro Ferreira, Márcia dos Santos Rizzo, Josy A. Osajima, Edson C. Silva-Filho, Cláudia Nunes, Maria Filomena de Jesus Raposo, Manuel A. Coimbra, Alessandra Braga Ribeiro, Marcília Pinheiro da Costa,
Mucilage extracted from chia seed (Salvia hispanica L.) (MCHs) has come to prominence in recent studies due to its attractive biological activities, improving the interest in developing Salvia hispanica as an industrial crop for sustainable source of bioactive polysaccharide. In this work, chia mucilage properties were evaluated, including physicochemical, photostability, cytocompatibility, and mucoadhesion characteristics. MCHs exhibited excellent photostability, with a degradation percentage of ...
Tópico(s): Nanocomposite Films for Food Packaging
2021 - Elsevier BV | Industrial Crops and Products
Produção Nacional
Revisado por pares
André Gonzaga dos Santos, Paulo Michel Pinheiro Ferreira, Gerardo Magela Vieira Júnior, Carla Cristina Perez, Aristeu Gomes Tininis, Geraldo Humberto Silva, Vanderlan da Silva Bolzani, Letícia V. Costa‐Lotufo, Cláudia do Ó Pessoa, Alberto José Cavalheiro,
Abstract An EtOH extract of the leaves of Casearia sylvestris afforded new clerodane diterpene, casearin X, together with the known compounds casearins B, D, L, and O, and caseargrewiin F. Casearin X degraded to the corresponding dialdehyde when stored in CDCl 3 . The diterpenes isolated were cytotoxic to human cancer cell lines, with caseargrewiin F being the most active and the new clerodane, casearin X, the second active compound with IC 50 values comparable to the positive control doxorubicin. ...
Tópico(s): Plant-Derived Bioactive Compounds
2010 - Wiley | Chemistry & Biodiversity
Valéria Papa, Solange Guizilini, Caroline Bublitz, Isadora S. Rocco, Camila Quaglio Bertini, Vivian Bertoni Xavier, Rodrigo Boemio Jaenisch, Eliana Vieira Moderno, Vanessa Marques Ferreira, Vera Lúcia dos Santos Alves, Michel Silva Reis,
Tópico(s): Heart Rate Variability and Autonomic Control
2020 - | Revista da Sociedade de Cardiologia do Estado de São Paulo
Produção Nacional
Revisado por pares
Paulo Michel Pinheiro Ferreira, André Gonzaga dos Santos, Aristeu Gomes Tininis, Patrícia Marçal da Costa, Alberto José Cavalheiro, Vanderlan da Silva Bolzani, Manoel Odorico de Moraes, Letícia V. Costa‐Lotufo, Raquel Carvalho Montenegro, Cláudia Pessoa,
Clerodane diterpenes have demonstrated cytotoxic, antiplasmodial and anti-ulcer properties. In the present work, we determined the cytotoxic effect of casearin L (Cas L), O (Cas O) and X (Cas X) and (−)-hardwickiic acid isolated from Casearia sylvestris leaves, and investigated the underlying mechanisms involved in in vitro cell death induced by Cas X in HL-60 leukemia cells (0.7, 1.5 and 3.0 μM). Cytotoxicity tests demonstrated that Cas X was the most active compound studied, showing greater cytotoxic ...
Tópico(s): Biological Stains and Phytochemicals
2010 - Elsevier BV | Chemico-Biological Interactions
Produção Nacional
Revisado por pares
Rosália Maria Tôrres de Lima, Antonielly Campinho dos Reis, José Victor de Oliveira Santos, José Roberto de Oliveira Ferreira, Antônio Lima Braga, José Williams Gomes de Oliveira Filho, Ag‐Anne Pereira Melo de Menezes, Ana Maria Oliveira Ferreira da Mata, Marcus Vinícius Oliveira Barros de Alencar, Débora Caroline do Nascimento Rodrigues, Paulo Michel Pinheiro Ferreira, Teresinha de Jesus Aguiar dos Santos Andrade, Juan Carlos Ramos Gonçalves, Felipe Cavalcanti Carneiro da Silva, João Marcelo de Castro e Sousa, Ana Amélia de Carvalho Melo Cavalcante,
Gingerol - [6]-gingerol ((S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone; [6]-G) - is a phenolic compound with several pharmacological properties. Herein, the aim of the study was to evaluate the toxicogenic effects of [6]-G on Artemia salina nauplii, Allium cepa, HL-60 cell line and Sarcoma 180 (S-180) ascitic fluid cells.For toxic and genotoxic analysis, it was used [6]-G concentrations of 5, 10, 20 and 40 μg mL-1. For cytotoxic evaluation using the MTT test (3- [4,5-dimethyl-thiazol-2-yl] -2,5-diphenyl ...
Tópico(s): Drug Transport and Resistance Mechanisms
2019 - Elsevier BV | Biomedicine & Pharmacotherapy
Produção Nacional
Revisado por pares
T.M.Q. Seregheti, Ana Paula Resende Pinto, Marlucy da Cruz Gonçalves, Amanda dos Santos Antunes, Wanessa da Silva de Almeida, Ranyelison Silva Machado, Jurandy do Nascimento Silva, Paulo Michel Pinheiro Ferreira, Cláudia Pessoa, Viviane Martins Rebello dos Santos, Andréa Mendes do Nascimento,
In this paper, we complement our previous study on the antiproliferative activity of Calea fruticosa (Asteraceae) by isolating the compounds apigenin-4',7-dimethyl ether (1), budlein A (2), quercetin (3), and cichoriin (4) from the plant's aerial parts. The antiproliferative activity of these compounds was evaluated by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method against human tumor cell lines. Compound 3 displayed moderate antiproliferative activity in three cell lines ( ...
Tópico(s): Morinda citrifolia extract uses
2020 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Paulo Michel Pinheiro Ferreira, Denise Barbosa Santos, Jurandy do Nascimento Silva, Amanda Freitas Goudinho, Carla Lorena Silva Ramos, Patrícia Canteri de Souza, Ricardo Sérgio Almeida, Diego Sousa Moura, Rhaul Oliveira, César Koppe Grisólia, Alberto José Cavalheiro, Ana Amélia de Carvalho Melo Cavalcante, José Roberto de Oliveira Ferreira, Manoel Odorico de Moraes, Cláudia Pessoa,
Extracts, essential oils and molecules from Casearia sylvestris have popularly shown pharmacological actions against chronic diseases, as anxiety, inflammation, cancer and dyslipidemia. In the context of antitumoral therapy, we investigated in vitro, ex vivo and in vivo toxicological changes induced by a Fraction with Casearins (FC) and its component Casearin X isolated from C. sylvestris on animal and vegetal cells, and upon invertebrates and mammals. Cytotoxicity was carried out using normal lines ...
Tópico(s): Plant-Derived Bioactive Compounds
2019 - Elsevier BV | Journal of Ethnopharmacology
Produção Nacional
Revisado por pares
Mário León Silva-Vergara, Zoilo Pires dè Camargo, Patricia Ferreira Silva, Michel Reis Abdalla, Ricardo Nilsson Sgarbieri, Anderson Messias Rodrigues, Keila Cristina dos Santos, Cristina Hueb Barata, Kennio Ferreira‐Paim,
Disseminated sporotrichosis occurs in individuals with impaired cellular immunity, such as in cases of neoplasia, transplantation, diabetes, and especially, acquired immunodeficiency syndrome. This report presents a 32-year-old Brazilian human immunodeficiency virus (HIV)-infected patient who developed a protracted condition of disseminated sporotrichosis with endocarditis, bilateral endophthalmitis, and lymphatic involvement. He needed cardiac surgery to replace the mitral valve. Sporothrix brasiliensis ...
Tópico(s): Parasitic Infections and Diagnostics
2012 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Produção Nacional
Revisado por pares
Carlos Eduardo Moreira Rodrigues, Maria Emília de Lima Tostes, Ubiratan Holanda Bezerra, Thiago Mota Soares, Edson Ortiz de Matos, Lázaro Serra Soares Filho, Elaine Cristina dos Santos Silva, Michel Ferreira Rendeiro, Carlos Jeferson da Silva Moura,
Energy losses are a fundamental issue in the electricity distribution sector, being an inevitable consequence of transporting energy from supplying sources to consumers’ installations and are becoming one of the factors to be considered in planning and operation of electrical distribution networks. So, electrical distribution losses must be continuously monitored so that they are kept within acceptable levels to ensure the business profitability as well as the good power quality of supplied energy. ...
Tópico(s): Islanding Detection in Power Systems
2021 - Multidisciplinary Digital Publishing Institute | Energies
Rodolphe Dos Santos Ferreira, Philippe Michel,
ABSTRACT The paper presents a simple loglinear macroeconomic model designed to discuss the essentials of Keynes' dynamic analysis in the General Theory and in the Treatise on Money . The model has a conventional static Aggregate Demand—Aggregate Supply block plus a three‐dimensional dynamic system involving the money wage and the expected level and rate of change of the output price. It illustrates Keynes' ideas, in particular on the nature of unemployment and on the stabilizing nature of money (as ...
Tópico(s): Monetary Policy and Economic Impact
2012 - Wiley | Metroeconomica
Produção Nacional
Revisado por pares
Janaína de Oliveira Brito-Monzani, Filipe Fernandes Stoyell‐Conti, Tânia Plens Shecaira, Michel Pablo dos Santos Ferreira Silva, Danielle da Silva Dias, Nathália Bernardes, Kátia De Angelis,
Cardiovascular autonomic dysfunction is associated with end organ damage and increased risk of mortality. Menopause and metabolic syndrome increase the risk for cardiorenal complications. In this study, we investigated the effects of aerobic or resistance exercise training on autonomic control of circulation and renal oxidative stress in a model of menopause and metabolic syndrome. Female Wistar rats and spontaneously hypertensive rats (SHR) were divided into 5 groups (n = 8): control (C), hypertensive ( ...
Tópico(s): Cardiovascular and exercise physiology
2020 - Elsevier BV | Experimental Gerontology
Produção Nacional
Revisado por pares
Rosália Maria Tôrres de Lima, Antonielly Campinho dos Reis, José Victor de Oliveira Santos, José Roberto de Oliveira Ferreira, José Williams Gomes de Oliveira Filho, Ana Carolina Soares Dias, Ag‐Anne Pereira Melo de Menezes, Ana Maria Oliveira Ferreira da Mata, Marcus Vinícius Oliveira Barros de Alencar, Teresinha de Jesus Aguiar dos Santos Andrade, Márcia Fernanda Correia Jardim Paz, Débora Caroline do Nascimento Rodrigues, Paulo Michel Pinheiro Ferreira, João Marcelo de Castro e Sousa, Siddhartha Kumar Mishra, Muhammad Torequl Islam, Ana Amélia de Carvalho Melo Cavalcante,
Abstract Background [6]-Gingerol [(S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone] is a phenolic substance reported for several ethnopharmacological usage by virtue of its antioxidant, antiemetic, anti-inflammatory and anticancer properties. This study assessed the antitumoral effects of [6]-Gingerol in primary cells of Sarcoma 180 as well as in peripheral blood lymphocytes of mice. Methods The effect of [6]-Gingerol was assessed by applying cytogenetic biomarkers as indicative of genotoxicity, ...
Tópico(s): Natural Compounds in Disease Treatment
2020 - Elsevier BV | Biomedicine & Pharmacotherapy
Rodolphe Dos Santos Ferreira, Philippe Michel,
Summary The principle of effective demand decomposes in two distinct propositions, one pertaining to the analysis of actual, the other to the analysis of equilibrium states. The authors suggest that Keynes' apparatus of aggregate supply and demand decomposes correspondingly in two pairs of aggregate functions. They thus extend to the supply side a duality which had already been noticed on the demand side. Such an extension leads to a reconsideration of the debate between two conflicting views of ...
Tópico(s): Political Economy and Marxism
1991 - | Recherches économiques de Louvain
Produção Nacional
Revisado por pares
Valéria Fernandes de Oliveira Sousa, Alberto Salgado Bandeira, Michel Douglas Santos Ribeiro, José Jaciel Ferreira dos Santos, Gisele Lopes dos Santos, Rosilene Agra da Silva, Patrício Borges Maracajá, José Eldo Costa,
O uso de plantas medicinais mostra-se como uma alternativa, para o tratamento e prevenção de doenças que acometem os animais, visto que, é um método de baixo custo e de fácil aquisição ao produtor. Desta forma, objetivou-se avaliar o conhecimento populacional no semiárido paraibano, a respeito do emprego de plantas com propriedades curativas para animais. A pesquisa foi realizada na 14ª Região Administrativa da Empresa de Assistência Técnica e Extensão Rural da Paraíba, sediada em Pombal-PB, promovendo- ...
Tópico(s): Bee Products Chemical Analysis
2020 - Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências | Research Society and Development
Produção Nacional
Revisado por pares
Lívia Queiroz de Sousa, Kátia da Conceição Machado, Samara Ferreira de Carvalho Oliveira, Lidiane da Silva Araújo, Evaldo dos Santos Monção-Filho, Ana Amélia de Carvalho Melo Cavalcante, Gerardo Magela Vieira Júnior, Paulo Michel Pinheiro Ferreira,
Amphibians present pharmacologically active aliphatic, aromatic and heterocyclic molecules in their skin as defense against microorganisms, predators and infections, such as steroids, alkaloids, biogenic amines, guanidine derivatives, proteins and peptides. Based on the discovered bioactive potential of bufadienolides, this work reviewed the contribution of amphibians, especially from members of Bufonidae family, as source of new cytotoxic and antitumor molecules, highlighting the mechanisms responsible ...
Tópico(s): Sesquiterpenes and Asteraceae Studies
2017 - Elsevier BV | Toxicon
Produção Nacional
Revisado por pares
Michel Pablo dos Santos Ferreira Silva, Maycon Júnior Ferreira, Tânia Plens Shecaira, Danielle da Silva Dias, Débora Conte Kimura, Maria Cláudia Irigoyen, Guiomar Nascimento Gomes, Kátia De Angelis,
Objective In this study, we aimed to investigate the effects of the concurrent exercise training (CET) associated with the enalapril maleate on blood pressure variability (BPV) and renal profile in an experimental model of arterial hypertension (AH) and postmenopause. Methods Female ovariectomized spontaneously hypertensive rats (SHR) were distributed into 4 groups (n = 8/group): sedentary (SO), sedentary + enalapril (SOE), trained (TO) and trained + enalapril (TOE). Both enalapril (3mg/kg) and CET (3 days/week) ...
Tópico(s): Cardiovascular and exercise physiology
2024 - Public Library of Science | PLoS ONE
Produção Nacional
Vivianne Rodrigues Amorim, Débora Caroline do Nascimento Rodrigues, Jurandy do Nascimento Silva, Carla Lorena Silva Ramos, Lívia Maria Nunes de Almeida, Antônia Amanda Cardoso de Almeida, Flaviano Ribeiro Pinheiro-Neto, Fernanda Regina de Castro Almeida, Márcia dos Santos Rizzo, Joilane Alves Pereira-Freire, Paulo Michel Pinheiro Ferreira,
Mauritia flexuosa L., traditionally known as “buriti”, exhibits chemoprotective properties including antioxidant, antithrombotic, and nutritional actions. The aim of this study was to examine the oral anti-inflammatory activity of epicarp, mesocarp and endocarp obtained from M. flexuosa fruits using in vivo models to verify physiological benefits. The anti-edematogenic action was determined using phlogistic agents to induce paw edema and peritonitis. Pro-inflammatory cytokines, cell migration of ...
Tópico(s): Phytochemistry and Bioactive Compounds
2021 - Taylor & Francis | Journal of Toxicology and Environmental Health
Produção Nacional
Edmar Vinícius de Carvalho, Joênes Mucci Pelúzio, Weder Ferreira dos Santos, Flávio Sérgio Afférri, Michel Antônio Dotto,
Objetivou-se com este trabalho estudar a estabilidade fenotípica de cultivares de soja, quanto à produção de grãos, em oito ensaios, quatro na cidade de Gurupi-TO e, quatro na cidade de Palmas - TO, conduzidos durante os anos de 2008 a 2012. Os ensaios foram instalados com delineamento em blocos casualizados, com quatro repetições, e onze cultivares de soja. Foram utilizadas as metodologias de análise de estabilidade de Eberhart e Russell (1966), Lin e Binns (1988) modificado por Carneiro (1998), e Annicchiarico ( ...
Tópico(s): Genetics and Plant Breeding
2013 - FUNDAÇÃO UNIVERSIDADE FEDERAL DE RORAIMA | Revista Agro mbiente On-line
Produção Nacional
Revisado por pares
Zaher Jabbour, Cássio do Nascimento, Bruna Gabriela dos Santos Kotake, Michel El‐Hakim, Janet E. Henderson, Rubens Ferreira de Albuquerque,
This study aimed to evaluate the capacity of whole-genome DNA probes prepared from human oral bacteria to cross-react with bacteria from the oral cavity of rats, and to assess the influence of alcohol ingestion on the animals' oral biofilm. Twenty four mature Wistar rats were equally divided in two groups. One group (control) was fed balanced diet of rat pellets and water. The alcohol-treated group (AT) received the same diet and 20% ethanol solution. Upon euthanasia after 30 days, bacterial samples ...
Tópico(s): Alcohol Consumption and Health Effects
2012 - Elsevier BV | Archives of Oral Biology
Produção Nacional
Revisado por pares
Éverton José Ferreira de Araújo, Guilherme Antônio Lopes de Oliveira, Lívia Queiroz de Sousa, Vanderlan da Silva Bolzani, Alberto José Cavalheiro, Adriana da Rocha Tomé, Ana Paula Peron, André Gonzaga dos Santos, Antônia Maria das Graças Lopes Citó, Cláudia Pessoa, Rivelilson Mendes de Freitas, Paulo Michel Pinheiro Ferreira,
Casearia sylvestris Swartz is a medicinal plant widely distributed in Brazil. It has anti-inflammatory, antiulcer and antitumor activities and is popularly used to treat snakebites, wounds, diarrhea, flu and chest colds. Its leaves are rich in oxygenated tricyclic cis-clerodane diterpenes, particulary casearins. Herein, we evaluated the antioxidant activities of a fraction with casearins (FC) isolated from C. sylvestris and histological changes on the central nervous system and livers of Mus musculus ...
Tópico(s): Pharmacology and Obesity Treatment
2015 - Brazilian Academy of Sciences | Anais da Academia Brasileira de Ciências
Produção Nacional
Revisado por pares
Andreza Portella Ribeiro, Ana Maria Graciano Figueiredo, José Osman dos Santos, Paulo Alves de Lima Ferreira, Gustavo Silveira Graudenz, Mauro Silva Ruiz, Michel Michaelovitch de Mahiques, Rubens César Lopes Figueira, Julio César Wasserman,
Purpose – The purpose of this paper is to address the case of toxic metal contamination of Sepetiba Bay caused by the Ingá Company. The paper reviews the history of the contamination and discusses the current presence of metals in the bay sediments, demonstrating that the toxic metals are clearly enriched. Sepetiba Bay is prone to significant dredging activities that make metals available in the food chain, affecting human populations, mainly fishermen communities. Design/methodology/approach – The ...
Tópico(s): Environmental and Social Impact Assessments
2015 - Emerald Publishing Limited | Management of Environmental Quality An International Journal
Produção Nacional
Revisado por pares
Evaldo dos Santos Monção Filho, Mariana Helena Chaves, Paulo Michel Pinheiro Ferreira, Cláudia Pessoa, Daisy Jereissati Barbosa Lima, Sarah Sant’ Anna Maranhão, Domingos de Jesus Rodrigues, Gerardo Magela Vieira Júnior,
Tópico(s): Cancer therapeutics and mechanisms
2021 - Elsevier BV | Toxicon
Produção Nacional
Revisado por pares
Gustavo Barreto Melo, Natasha Ferreira Santos da Cruz, Lydianne Lumack do Monte Agra, Geoffrey G. Emerson, Luiz H. Lima, Vaida Linkuvienė, Maurício Maia, Michel Eid Farah, John F. Carpenter, Eduardo B. Rodrigues, Christine Probst,
Abstract Purpose This study aimed to quantify the amount of silicone oil (SO) released across a variety of syringe and needle models routinely used for intravitreal injection. Methods The release of SO was assessed in eight models of syringes, two of which were reported to be ‘SO‐free’, and eleven models of needles with unknown SO content. To evaluate SO release within the context of anti‐VEGF therapeutics, syringes were evaluated using aflibercept, bevacizumab, buffer, ziv‐aflibercept and formulation ...
Tópico(s): Systemic Lupus Erythematosus Research
2021 - Wiley | Acta Ophthalmologica
Produção Nacional
Revisado por pares
José Williams Gomes de Oliveira Filho, Muhammad Torequl Islam, Eunüs S. Ali, Shaikh Jamal Uddin, José Victor de Oliveira Santos, Marcus Vinícius Oliveira Barros de Alencar, Antônio Luíz Gomes Júnior, Márcia Fernanda Correia Jardim Paz, Maria dos Remédios Mendes de Brito, João Marcelo de Castro e Sousa, Subrata Shaw, Maria das Graças Freire de Medeiros, Sandra Maria Mendes de Moura Dantas, Hercília Maria Lins Rolim, Paulo Michel Pinheiro Ferreira, Mohammad Amjad Kamal, Magdalena D. Pieczynska, Niranjan Das, Vijai Kumar Gupta, Andrei Mocan, Teresinha de Jesus Aguiar dos Santos Andrade, Brahma N. Singh, Siddhartha Kumar Mishra, Atanas G. Atanasov, Ana Amélia de Carvalho Melo Cavalcante,
Citrinin (CIT) is a mycotoxin which causes contamination in the food and is associated with different toxic effects. A web search on CIT has been conducted covering the timespan since 1946. The accumulated data indicate that CIT is produced by several fungal strains belonging to Penicillium, Aspergillus and Monascus genera, and is usually found together with another nephrotoxic mycotoxin, ochratoxin A. Although, it is evident that CIT exposure can exert toxic effects on the heart, liver, kidney, ...
Tópico(s): Plant tissue culture and regeneration
2017 - Elsevier BV | Food and Chemical Toxicology
Produção Nacional
Revisado por pares
Marcus Vinícius Oliveira Barros de Alencar, Muhammad Torequl Islam, Rosália Maria Tôrres de Lima, Márcia Fernanda Correia Jardim Paz, Antonielly Campinho dos Reis, Ana Maria Oliveira Ferreira da Mata, José Williams Gomes de Oliveira Filho, Gilberto Santos Cerqueira, Paulo Michel Pinheiro Ferreira, João Marcelo de Castro e Sousa, Mohammad S. Mubarak, Ana Amélia de Carvalho Melo Cavalcante,
Abstract Phytol (PHY) (3,7,11,15‐tetramethylhexadec‐2‐en‐1‐ol) exhibits various pharmacological properties including toxicity and cytotoxicity, and exerts antitumor activity. Owing to the urgent need of new pharmaceutical formulations for breast cancer therapy, this study aimed at the evaluation of antitumor activity of PHY in 7,12‐dimethylbenzanthracene‐cancer‐induced animal model. Comet assay was employed to evaluate the cytogenetics, DNA repair, and antigenotoxic activities of PHY in neoplastic ( ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2018 - Wiley | IUBMB Life
Produção Nacional
Revisado por pares
Cícero Úrban, Luciano Fernandes Chala, Selma di Pace Bauab, Marcela Brisighelli Schaefer, Radiá Pereira dos Santos, Norma Médicis de Albuquerque Maranhão, Ana Lucia Kefalas, José Michel Kalaf, Carlos Alberto Pecci Ferreira, Ellyete de Oliveira Canella, Joäo Emílio Peixoto, Heverton Leal Ernesto de Amorim, Helio Sebastião Amâncio de Camargo,
To present the current recommendations for breast cancer screening in Brazil, as devised by the Brazilian College of Radiology and Diagnostic Imaging, the Brazilian Breast Disease Society, and the Brazilian Federation of Gynecological and Obstetrical Associations.We analyzed scientific studies available in the Medline and Lilacs databases. In the absence of evidence, the recommendations reflected the consensus of a panel of experts.Annual mammography screening is recommended for women 40-74 years ...
Tópico(s): Breast Cancer Treatment Studies
2017 - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem | Radiologia Brasileira
Produção Nacional
Revisado por pares
Cícero Úrban, Luciano Fernandes Chala, Selma di Pace Bauab, Marcela Brisighelli Schaefer, Radiá Pereira dos Santos, Norma Médicis de Albuquerque Maranhão, Ana Lucia Kefalas, José Michel Kalaf, Carlos Alberto Pecci Ferreira, Ellyete de Oliveira Canella, Joäo Emílio Peixoto, Heverton Leal Ernesto de Amorim, Helio Sebastião Amâncio de Camargo,
In several countries, organized screening programs have led to a reduction in breast cancer mortality.[1] [2] In Brazil, despite all efforts, there has been an increase in the incidence of and mortality associated with breast cancer.[3] [4] [5] One peculiarity of breast cancer in Brazil and in other developing countries is that its incidence in women between 40 and 50 years of age is proportionately higher than that reported for developed countries.[6] [7] [8]
Tópico(s): Colorectal Cancer Screening and Detection
2017 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia