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Antonio Granata, Simeone Andrulli, Fulvio Fiorini, Francesco Logias, Michele Figuera, Renzo Mignani, Antonio Basile, Carmelo Erio Fiore,

Variations in the course of the blood vessels are often incidental findings during clinical examination. Persistent left superior vena cava (PLSVC) is an uncommon anomaly, estimated to be present in about 0.3–0.5% of healthy individuals and in about 3–10% of patients with congenital heart disease. It results from the failure of the left anterior cardinal vein to degenerate during embryological development. Serious complications such as shock, angina and cardiac arrest have been described during catheterization ...

Tópico(s): Central Venous Catheters and Hemodialysis

2009 - SAGE Publishing | The Journal of Vascular Access

Artigo Revisado por pares

Antonio Granata, Antonio Basile, Michele Figuera, Renzo Mignani, C. E. Fiore,

Tuberous sclerosis complex (TSC) is a genetic and systemic disorder characterized by benign hamartomatous tumors that involve multiple organ systems. The classical clinical triad of TSC consists of seizure, adenoma sebaceum (facial angiofibromata) and mental retardation. Renal angiomyolipomas are documented in approximately 40 - 80% of tuberous sclerosis patients and usually are small and asymptomatic. Less frequently nodules are large and lead to retroperitoneal hemorrhage. In these cases diagnosis ...

Tópico(s): Tuberous Sclerosis Complex Research

2009 - Dustri-Verlag | Clinical Nephrology

Artigo Acesso aberto Revisado por pares

Antonio Pisani, Luigi Petruzzelli Annicchiarico, Angela Maria Pellegrino, Dario Bruzzese, Sandro Feriozzi, Massimo Imbriaco, Enrico Tedeschi, Sirio Cocozza, D Rosa, Renzo Mignani, Massimiliano Veroux, Yuri Battaglia, Daniela Concolino, Simona Sestito, Federico Pieruzzi, Leonardo Caroti, Raffaele Manna, Carmela Zizzo, Michele Santangelo, Massimo Sabbatini, Eleonora Riccio,

Fabry's disease (FD) is a rare, multi-organ lysosomal disease, caused by the deficiency of the enzyme α-galactosidase A, and is difficult to diagnose. Although parapelvic cysts (PC) were previously associated with FD, their prevalence and significance are unclear. The present study aimed to: (i) evaluate, by renal ultrasound, the real prevalence of PC and of their determinants in a multicentre, nationwide cohort of FD patients (n = 173, Study 1) and (ii) ascertain whether a greater accuracy of PC detection ...

Tópico(s): Cellular transport and secretion

2017 - Oxford University Press | Nephrology Dialysis Transplantation

Artigo Acesso aberto

Shuang‐Nan Zhang, M. Feroci, A. Santangelo, Yongwei Dong, Hua Feng, F. J. Lu, K. Nandra, Z. S. Wang, S. Zhang, E. Bozzo, S. Brandt, Alessandra De Rosa, Lijun Gou, M. Hernanz, M. van der Klis, Xiang‐Dong Li, Yaqiang Liu, P. Orleański, Giovanni Pareschi, M. Pohl, Juri Poutanen, Jin Qu, S. Schanne, L. Stella, P. Uttley, Anna L. Watts, Renxin Xu, Wenfei Yu, J. J. M. in ’t Zand, Silvia Zane, Laura Álvarez, L. Amati, L. Baldini, Cosimo Bambi, S. Basso, Sudip Bhattacharyya, R. Bellazzini, T. Belloni, P. Bellutti, S. Bianchi, A. Brez, Michal Bursa, V. Burwitz, C. Budtz-Jørgensen, Ilaria Caiazzo, R. Campana, X. L. Cao, P. Casella, C. Y. Chen, Li Chen, Tianxiang Chen, Y. Chen, Y. Chen, Y. P. Chen, M. Civitani, F. Coti Zelati, Wei Cui, W. W. Cui, Z. G. Dai, E. Del Monte, D. de Martino, Sergio Di Cosimo, S. Diebold, Michal Dovčiak, I. Donnarumma, Victor Doroshenko, P. Esposito, Y. Evangelista, Y. Favre, P. Friedrich, F. Fuschino, J. L. Gálvez Sanchez, Zeliang Gao, Mingyu Ge, O. Gevin, D. Goetz, D. W. Han, Jeremy Heyl, Jiří Horák, W. Hu, Feifei Huang, Qunshan Huang, R. Hudec, D. Huppenkothen, G. L. Israel, A. Ingram, V. Karas, D. Karelin, Peter Jenke, L. Ji, S. Korpela, D. Kunneriath, C. Labanti, Gang Li, Xinxi Li, Li Chen, E. W. Liang, Olivier Limousin, L. C.-C. Lin, Z. X. Ling, H. Liu, H. W. Liu, Z. Liu, Bo Lü, N. Lund, Dong Lai, B. Luo, T. Luo, Bin Ma, Simin Mahmoodifar, M. Marisaldi, A. Martindale, Norbert Meidinger, Y. P. Men, M. Michalska, R. Mignani, M. Minuti, S. Motta, Fabio Muleri, J. Neilsen, M. Orlandini, A. T. Pan, Alessandro Patruno, emanuele perinati, A. Picciotto, C. Piemonte, Michele Pinchera, A. Rachevski, M. Rapisarda, N. Rea, Elena M. Rossi, A. Rubini, G. Sala, X. W. Shu, C. Sgrò, Z. X. Shen, P. Soffitta, L. M. Song, G. Spandre, G. Stratta, T. Strohmayer, Liang Sun, Jiří Svoboda, G. Tagliaferri, C. Tenzer, T. M. Hong, R. Taverna, Gabriel Török, R. Turolla, A. Vacchi, Jian Wang, D. Walton, Kai Wang, Junfeng Wang, R. J. Wang, Y. F. Wang, Shanshan Weng, J. Wilms, B. Winter, X. Wu, Xue-Feng Wu, S. L. Xiong, Y. P. Xu, Yongquan Xue, Zhen Yan, S. Yang, Xiaoming Yang, H. J. Yang, Fang-Ting Yuan, W. Yuan, Ye‐Fei Yuan, G. Zampa, N. Zampa, A. A. Zdziarski, C. Zhang, C. L. Zhang, Long Zhang, X. Zhang, Z. Zhang, Wenda Zhang, S. J. Zheng, Ping Zhou, X. Zhou,

eXTP is a science mission designed to study the state of matter under extreme conditions of density, gravity and magnetism. Primary goals are the determination of the equation of state of matter at supra-nuclear density, the measurement of QED effects in highly magnetized star, and the study of accretion in the strong-field regime of gravity. Primary targets include isolated and binary neutron stars, strong magnetic field systems like magnetars, and stellar-mass and supermassive black holes. The ...

Tópico(s): Astronomical Observations and Instrumentation

2016 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE

Artigo Acesso aberto Revisado por pares

Daniela Zizioli, Simona Bernardi, Marco Varinelli, Mirko Farina, Luca Mignani, Katia Bosio, Dario Finazzi, Eugenio Monti, Nicola Polverelli, Michele Malagola, Elisa Borsani, Giuseppe Borsani, Domenico Russo,

Zebrafish has proven to be a versatile and reliable experimental in vivo tool to study human hematopoiesis and model hematological malignancies. Transgenic technologies enable the generation of specific leukemia types by the expression of human oncogenes under specific promoters. Using this technology, a variety of myeloid and lymphoid malignancies zebrafish models have been described. Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasia characterized by the BCR-ABL1 fusion gene, ...

Tópico(s): Cancer-related gene regulation

2021 - Multidisciplinary Digital Publishing Institute | Cells

Artigo Revisado por pares

S. Artioli, E Mignani, Michele Guerra,

Tópico(s): Hepatitis C virus research

1998 - Elsevier BV | Journal of Hepatology

Revisão Acesso aberto Revisado por pares

Giuseppe Felice Mangiatordi, Maria Maddalena Cavalluzzi, Pietro Delre, Giuseppe Lamanna, Maria Cristina Lumuscio, Michele Saviano, Jean‐Pierre Majoral, Serge Mignani, Andrea Duranti, Giovanni Lentini,

The endocannabinoid system (ECS) plays a very important role in numerous physiological and pharmacological processes, such as those related to the central nervous system (CNS), including learning, memory, emotional processing, as well pain control, inflammatory and immune response, and as a biomarker in certain psychiatric disorders. Unfortunately, the half-life of the natural ligands responsible for these effects is very short. This perspective describes the potential role of the inhibitors of the ...

Tópico(s): Neurotransmitter Receptor Influence on Behavior

2023 - Multidisciplinary Digital Publishing Institute | Biomedicines

Artigo Acesso aberto Revisado por pares

L. Amati, P. T. O’Brien, D. Götz, E. Bozzo, C. Tenzer, F. Frontera, G. Ghirlanda, C. Labanti, J. P. Osborne, G. Stratta, N. R. Tanvir, R. Willingale, Primo Attinà, R. Campana, A. J. Castro‐Tirado, Cristiano Contini, F. Fuschino, A. Gomboc, R. Hudec, P. Orleański, E. Renotte, Tomaž Rodič, Z. Bagoly, A. W. Blain, Paul X. Callanan, S. Covino, Andrea Ferrara, E. Le Floc’h, M. Marisaldi, S. Mereghetti, P. Rosati, A. Vacchi, P. D’Avanzo, P. Giommi, S. Piranomonte, L. Piro, V. Reglero, A. Rossi, A. Santangelo, R. Salvaterra, G. Tagliaferri, S. D. Vergani, S. Vinciguerra, M. S. Briggs, E. Campolongo, R. Ciolfi, V. Connaughton, B. Cordier, B. Morelli, M. Orlandini, C. Adami, A. Argan, J. L. Atteia, N. Auricchio, L. G. Balázs, G. Baldazzi, S. Basa, Rupal Basak, P. Bellutti, M. G. Bernardini, G. Bertuccio, J. Braga, M. Branchesi, S. Brandt, E. Brocato, C. Budtz‐Jørgensen, A. Bulgarelli, L. Burderi, J. B. Camp, Salvatore Capozziello, Joseph Caruana, P. Casella, B. Cenko, P. Chardonnet, B. Ciardi, S. Colafrancesco, Maria Giovanna Dainotti, V. D’Elia, D. de Martino, M. De Pasquale, E. Del Monte, M. Della Valle, A. Drago, Y. Evangelista, M. Feroci, F. Finelli⋆, M. Fiorini, J. P. U. Fynbo, A. Gal‐Yam, B. Gendre, G. Ghisellini, A. Grado, C. Guidorzi, M. Hafizi, L. Hanlon, J. Hjorth, L. Izzo, L. L. Kiss, P. Kumar, I. Kuvvetli, Michèle Lavagna, T. Li, F. Longo, Maxim Lyutikov, Umberto Maio, E. Maiorano, P. Malcovati, D. Malesani, R. Margutti, A. Martín-Carrillo, N. Masetti, S. McBreen, R. Mignani, G. Morgante, C. G. Mundell, H.U. Nargaard-Nielsen, L. Nicastro, E. Palazzi, S. Paltani, F. Panessa, Giovanni Pareschi, Asaf Pe’er, A. V. Penacchioni, E. Pian, E. Piedipalumbo, Tsvi Piran, G. Rauw, M. Razzano, A. Read, L. Rezzolla, P. Romano, R. Ruffini, S. Savaglio, V. Sguera, P. Schady, Warrent Skidmore, L. M. Song, E. R. Stanway, R. L. C. Starling, M. Topinka, E. Troja, M. van Putten, E. Vanzella, S. Vercellone, C. Wilson‐Hodge, Daisuke Yonetoku, G. Zampa, Nicola Zampa, B. Zhang, B.B. Zhang, S. Zhang, Shuang‐Nan Zhang, L. A. Antonelli, Federica Bianco, Sonila Boçi, M. Boër, M. T. Botticella, O. Boulade, R. C. Butler, S. Campana, Fiamma Capitanio, A. Celotti, Y. Chen, M. Colpi, A. Comastri, Jean-Gabriel Cuby, M. Dadina, A. De Luca, Yuxin 雨欣 Dong 董, S. Ettori, P. Gandhi, E. Geza, J. Greiner, S. Guiriec, J. Harms, M. Hernanz, A. Hornstrup, Ian Hutchinson, G. L. Israel, P. G. Jonker, Yuki Kaneko, N. Kawai, K. Wiersema, Seppo A. Korpela, V. LeBrun, F. J. Lu, Andrew MacFadyen, G. Malaguti, L. Maraschi, A. Melandri, M. Modjaz, David C. Morris, N. Omodei, A. Paizis, Petr Páta, V. Petrosian, A. Rachevski, James E. Rhoads, F. Ryde, L. Sabau-Graziati, N. Shigehiro, M. R. Sims, J. Soomin, Dorottya Szécsi, Y. Urata, M. Uslenghi, L. Valenziano, G. Vianello, S. Vojtech, D. Watson, Jan H. Zicha,

THESEUS is a space mission concept aimed at exploiting Gamma-Ray Bursts for investigating the early Universe and at providing a substantial advancement of multi-messenger and time-domain astrophysics. These goals will be achieved through a unique combination of instruments allowing GRB and X-ray transient detection over a broad field of view (more than 1sr) with 0.5-1 arcmin localization, an energy band extending from several MeV down to 0.3 keV and high sensitivity to transient sources in the soft ...

Tópico(s): Astrophysics and Cosmic Phenomena

2018 - Elsevier BV | Advances in Space Research