Manuel Ramos‐Casals, R. Pérez-Álvarez, Belchin Kostov, Ricardo Gómez-de-la-Torre, Carlos Feijoo-Massó, J. Chara-Cervantes, Blanca Pinilla, Andrés González García, José Salvador García Morillo, Miguel López-Dupla, B. De-Escalante, Javier Rascón, P. Pérez‐Guerrero, Mariona Bonet, Gracia Cruz-Caparrós, Ana Alguacil, José Luis Callejas‐Rubio, Eva Calvo, Cristina Soler, Ángel Robles‐Marhuenda, Borja de Miguel-Campo, Pedro Oliva‐Nacarino, Jorge Estela-Herrero, Lucio Pallarés, Pilar Brito‐Zerón, Yolanda Blanco, Manuel Ramos‐Casals, R. Pérez-Álvarez, Belchin Kostov, Ricardo Gómez-de-la-Torre, Carlos Feijoo-Massó, J. Chara-Cervantes, Blanca Pinilla, Andrés González García, José Salvador García Morillo, Miguel López-Dupla, B. De-Escalante, Javier Rascón, P. Pérez‐Guerrero, Mariona Bonet, Gracia Cruz-Caparrós, Ana Alguacil, José Luis Callejas‐Rubio, E. Calvo, Cristina Soler, Ángel Robles‐Marhuenda, Borja de Miguel-Campo, Pedro Oliva‐Nacarino, Jorge Estela-Herrero, L Pallarés, Pilar Brito‐Zerón, Yolanda Blanco, Mercedes Pérez-Conesa, Eva Fonseca‐Aizpuru, Miriam Akasbi, G. De-la-Red, E. Peral-Gutiérrez, J.F. Gómez-Cerezo, Sara Rodríguez Fernández, A Gato, Antonio Javier Chamorro Fernández, C. Morcillo, I Ojeda, M.J. Vives, M. Penadés, M. De-Vicente, Xavier Bosch, M. Pérez-de-Lis, Borja Gracia-Tello, Neera Toledo Samaniego, Antoni Sisó‐Almirall,
To analyze the frequency and clinical phenotype of neurosarcoidosis (NS) in one of the largest nationwide cohorts of patients with sarcoidosis reported from southern Europe. NS was evaluated according to the Diagnostic Criteria for Central Nervous System and Peripheral Nervous System Sarcoidosis recently proposed by Stern et al. Pathologic confirmation of granulomatous disease was used to subclassify NS into definite (confirmation in neurological tissue), probable (confirmation in extraneurological ...
Tópico(s): Amyloidosis: Diagnosis, Treatment, Outcomes
2021 - Nature Portfolio | Scientific Reports
Raquel García-Vílchez, Ana M. Añazco-Guenkova, Sabine Dietmann, Judith López, Virginia Morón-Calvente, Silvia D’Ambrosi, Paz Nombela, Kepa Zamacola, Isabel Mendizabal, Saioa García-Longarte, Amaia Zabala-Letona, Ianire Astobiza, Sonia Fernández, Alejandro Paniagua, Borja Miguel‐López, Virginie Marchand, Diego Alonso‐López, Angelika Merkel, Ignacio García‐Tuñón, Aitziber Ugalde‐Olano, Ana Loizaga‐Iriarte, Isabel Lacasa-Viscasillas, Miguel Unda, Mikel Azkargorta, Félix Elortza, Laura Bárcena, Monika González-Lopez, Ana M. Aransay, Tomás Di Domenico, Manuel Sánchez‐Martín, Javier De Las Rivas, Sònia Guil, Yuri Motorin, Mark Helm, Pier Paolo Pandolfi, Arkaitz Carracedo, Sandra Blanco,
Abstract Newly growing evidence highlights the essential role that epitranscriptomic marks play in the development of many cancers; however, little is known about the role and implications of altered epitranscriptome deposition in prostate cancer. Here, we show that the transfer RNA N 7 -methylguanosine (m 7 G) transferase METTL1 is highly expressed in primary and advanced prostate tumours. Mechanistically, we find that METTL1 depletion causes the loss of m 7 G tRNA methylation and promotes the biogenesis ...
Tópico(s): Cancer-related molecular mechanisms research
2023 - BioMed Central | Molecular Cancer
Paz Nombela, Borja Miguel‐López, Sandra Blanco,
Abstract RNA modifications have recently emerged as critical posttranscriptional regulators of gene expression programmes. Significant advances have been made in understanding the functional role of RNA modifications in regulating coding and non-coding RNA processing and function, which in turn thoroughly shape distinct gene expression programmes. They affect diverse biological processes, and the correct deposition of many of these modifications is required for normal development. Alterations of ...
Tópico(s): RNA Research and Splicing
2021 - BioMed Central | Molecular Cancer
Lorenzo Romero Carlota, Goacute mez Borja Miguel Aacute ngel, Alej, Mollaacute Descals ro,
As in physical environments, one of the most important research topics is related to the effects of the characteristics of these new interactive virtual environments on different dimensions of human behaviour. This is particularly relevant in the case of consumer shopping behaviour on the internet. In this line, research on webmosphere, and specifically, the impact of utilitarian and hedonic atmospheric dimensions on shopper responses, is an interesting topic to study the more appropriate designs ...
Tópico(s): Spatial Cognition and Navigation
2011 - Academic Journals | AFRICAN JOURNAL OF BUSINESS MANAGEMENT
José Cuesta, Borja López-Nova, Miguel Niño‐Zarazúa,
... Measurement, and a Global EstimateAuthors/Editors: Jose Cuesta, Borja López-Nova, Miguel Niño-ZarazúaJose Cuesta, Borja López-Nova, Miguel Niño-Zarazúahttps://doi.org/10.1596/1813-9450- ...
Tópico(s): Gender, Labor, and Family Dynamics
2022 - | World Bank policy research working paper
Miguel Molina–Borja, Miguel Ángel Rodríguez-Domínguez,
The aim was to study as to how biometric and life-history traits of endemic lacertids in the Canary Islands (genus Gallotia) may have evolved, and possible factors affecting the diversification process of this taxon on successively appearing islands have been deduced. To that end, comparative analyses of sexual dimorphism and scaling of different body, head and life-history traits to body size in 10 species/subspecies of Gallotia have been carried out. Both Felsenstein's independent contrasts and ...
Tópico(s): Species Distribution and Climate Change
2004 - Wiley | Journal of Zoological Systematics & Evolutionary Research
Miguel Molina–Borja, Miguel Ángel Rodríguez-Domínguez, Claribel González-Ortega, Martha L. Bohórquez-Alonso,
We compared sexual dimorphism of body and head traits from adult lizards of populations of Gallotia caesaris living in ecologically different habitats of El Hierro and La Gomera. Males had larger body sizes than females, and sexual size and shape dimorphisms were greater in a population from La Gomera than in three populations from El Hierro. Multivariate analyses of variance, using linear and shape-adjusted traits, showed that the populations differed significantly in body and head traits, with ...
Tópico(s): Plant and animal studies
2010 - The Society for the Study of Amphibians and Reptiles | Journal of Herpetology
Pilar Brito‐Zerón, R. Pérez-Álvarez, Carlos Feijoo-Massó, Borja Gracia-Tello, Andrés González García, Ricardo Gómez-de-la-Torre, Ana Alguacil, Miguel López-Dupla, Ángel Robles‐Marhuenda, José Salvador García Morillo, Mariona Bonet, Gracia Cruz-Caparrós, Eva Fonseca‐Aizpuru, Miriam Akasbi, José Luis Callejas‐Rubio, Borja de Miguel-Campo, M. Pérez-de-Lis, Manuel Ramos‐Casals, B. De-Escalante, J. Chara-Cervantes, Mercedes Pérez-Conesa, Javier Rascón, L Pallarés, P. Pérez‐Guerrero, G. De-la-Red, E. Calvo, Cristina Soler, E. Peral-Gutiérrez, J.F. Gómez-Cerezo, Sara Rodríguez Fernández, Blanca Pinilla, Neera Toledo Samaniego, A Gato, Antonio Javier Chamorro Fernández, C. Morcillo, I Ojeda, M.J. Vives, B. de-Miguel, M. Penadés, M. De-Vicente,
To analyze whether immune-mediated diseases (IMDs) occurs in sarcoidosis more commonly than expected in the general population, and how concomitant IMDs influence the clinical presentation of the disease.We searched for coexisting IMDs in patients included in the SARCOGEAS-cohort, a multicenter nationwide database of consecutive patients diagnosed according to the ATS/ESC/WASOG criteria. Comparisons were made considering the presence or absence of IMD clustering, and odds ratios (OR) and their 95% ...
Tópico(s): IgG4-Related and Inflammatory Diseases
2021 - Elsevier BV | Joint Bone Spine
R. Pérez-Álvarez, Pilar Brito‐Zerón, Belchin Kostov, Carlos Feijoo-Massó, G. Fraile, Ricardo Gómez-de-la-Torre, B. De-Escalante, Miguel López-Dupla, Ana Alguacil, J. Chara-Cervantes, Mercedes Pérez-Conesa, Javier Rascón, José Salvador García Morillo, P. Pérez‐Guerrero, Eva Fonseca‐Aizpuru, Miriam Akasbi, Mariona Bonet, José Luis Callejas‐Rubio, L Pallarés, Manuel Ramos‐Casals, R. Pérez-Álvarez, Pilar Brito‐Zerón, Belchin Kostov, Carlos Feijoo-Massó, G. Fraile, Ricardo Gómez-de-la-Torre, B. De-Escalante, Miguel López-Dupla, Ana Alguacil, J. Chara-Cervantes, Mercedes Pérez-Conesa, Javier Rascón, José Salvador García Morillo, P. Pérez‐Guerrero, Eva Fonseca‐Aizpuru, Miriam Akasbi, Mariona Bonet, José Luis Callejas‐Rubio, G. De-la-Red, E. Calvo, Cristina Soler, E. Peral-Gutiérrez, J.F. Gómez-Cerezo, Gracia Cruz-Caparrós, Sara Rodríguez Fernández, Blanca Pinilla, A Gato, Antonio Javier Chamorro Fernández, C. Morcillo, Ángel Robles‐Marhuenda, I Ojeda, M.J. Vives, Borja de Miguel-Campo, M. Penadés, M. De-Vicente, Xavier Bosch, M. Pérez-de-Lis, Andrés González García, C. Yllera, Borja Gracia-Tello, Alexandre Pérez‐González, M. Pedrosa-Aragón, Carles Tolosa, Antoni Sisó‐Almirall, L Pallarés, Manuel Ramos‐Casals,
Background To analyze the association between Scadding radiological stages of sarcoidosis at diagnosis and the disease phenotype (epidemiology, clinical presentation and extrathoracic involvement) in one of the largest cohorts of patients with sarcoidosis reported from southern Europe. Methods The SARCOGEAS-Study Group includes a multicenter database of consecutive patients diagnosed with sarcoidosis according to the WASOG 1999 criteria. Extrathoracic disease at diagnosis was defined according to ...
Tópico(s): Autoimmune and Inflammatory Disorders
2019 - Elsevier BV | European Journal of Internal Medicine
Produção Nacional
Revisado por pares
Soledad Retamozo, Nihan Acar‐Denizli, Ildikó Fanny Horváth, Wan‐Fai Ng, Astrid Rasmussen, Dong Xu, Xiaomei Li, Chiara Baldini, Peter Olsson, Roberta Priori, Raphaèle Séror, Jacques-Éric Gottenberg, Aike A. Kruize, Gabriela Hernández‐Molina, Arjan Vissink, Pulukool Sandhya, Berkan Armağan, Luca Quartuccio, Agata Sebastian, Sonja Praprotnik, Elena Bartoloni, Seung‐Ki Kwok, Marika Kvarnström, Maureen Rischmueller, Roser Soláns-Laqué, D. Sène, Sandra Gofinet Pasoto, Yasunori Suzuki, David Isenberg, Valéria Valim, Gunnel Nordmark, Hideki Nakamura, Virgínia Fernandes Moça Trevisani, Benedikt Hofauer, Antoni Sisó‐Almirall, Roberto Giacomelli, Valérie Devauchelle‐Pensec, Stefano Bombardieri, Fabiola Atzeni, Daniel Hammenfors, B. Maure, Steven E. Carsons, Tamer A. Gheita, Isabel Sánchez‐Berná, Miguel López-Dupla, Jacques Morel, Nevsun İnanç, Eva Fonseca‐Aizpuru, C. Morcillo, Cristina Vollenweider, Sheila Melchor, Marcos Vázquez, Ericka Díaz-Cuiza, Sandra Consani-Fernández, Borja De-Miguel-Campo, Antónia Szántó, Stefano Bombardieri, Angelica Gattamelata, Anneline C. Hinrichs, Jorge Sánchez‐Guerrero, Debashish Danda, Levent Kılıç, Salvatore De Vita, Piotr Wiland, Roberto Gerli, Sung‐Hwan Park, Marie Wahren‐Herlenius, Hendrika Bootsma, Xavier Mariette, Manuel Ramos‐Casals, Pilar Brito‐Zerón,
To analyse how the main components of the disease phenotype (sicca symptoms, diagnostic tests, immunological markers and systemic disease) can be driven by the age at diagnosis of primary Sjögren's syndrome (pSS).By January 2021, the participant centres had included 12,753 patients from 25 countries that fulfilled the 2002/2016 classification criteria for pSS. The age at diagnosis was defined as the time when the attending physician confirmed fulfilment of the criteria. Patients were clustered according ...
Tópico(s): Inflammasome and immune disorders
2021 - Springer Vienna | Clinical and Experimental Rheumatology
Produção Nacional
Revisado por pares
Gabriela Hernández‐Molina, Belchin Kostov, Pilar Brito‐Zerón, Arjan Vissink, Thomas Mandl, Anneline C. Hinrichs, Luca Quartuccio, Chiara Baldini, Raphaèle Séror, Antónia Szántó, David Isenberg, Roberto Gerli, Gunnel Nordmark, Astrid Rasmussen, Roser Soláns-Laqué, Benedikt Hofauer, D. Sène, Sandra Gofinet Pasoto, Maureen Rischmueller, Sonja Praprotnik, Tamer A. Gheita, Debashish Danda, Berkan Armağan, Yasunori Suzuki, Valéria Valim, Valérie Devauchelle‐Pensec, Soledad Retamozo, Marika Kvarnström, Agata Sebastian, Fabiola Atzeni, Roberto Giacomelli, Steven E. Carsons, Seung‐Ki Kwok, Hideki Nakamura, Virgínia Fernandes Moça Trevisani, Alejandra Flores-Chávez, Xavier Mariette, Manuel Ramos‐Casals, Pilar Brito‐Zerón, Alejandra Flores-Chávez, Manuel Ramos‐Casals, Ildikó Fanny Horváth, Antónia Szántó, Tünde Tarr, F Ng, Astrid Rasmussen, Darise Farris, Dong Xu, Yan Zhang, Xingyuan Li, Baoshan Xu, Chiara Baldini, Stefano Bombardieri, Thomas Mandl, Peter Olsson, Roberta Priori, Federico Giardina, Raffaella Izzo, Raphaèle Séror, Xavier Mariette, Jacques-Éric Gottenberg, Aike A. Kruize, Anneline C. Hinrichs, Hendrika Bootsma, Arjan Vissink, Debashish Danda, Pulukool Sandhya, Gabriela Hernández‐Molina, Jorge Sánchez‐Guerrero, Berkan Armağan, Levent Kılıç, Umut Kalyoncu, Luca Quartuccio, Saviana Gandolfo, Salvatore De Vita, Sonja Praprotnik, Agata Sebastian, Piotr Wiland, Roberto Gerli, Elena Bartoloni, S-K Kwok, So Hyun Park, Marika Kvarnström, Marie Wahren‐Herlenius, Maureen Rischmueller, Sarah Downie‐Doyle, Roser Soláns-Laqué, D. Sène, Sandra Gofinet Pasoto, Yasunori Suzuki, M Kawano, David Isenberg, Gunnel Nordmark, Valéria Valim, Hideki Nakamura, Toshimasa Shimizu, Shinya Nishihata, Takashi Nakamura, Yukinori Takagi, Virgínia Fernandes Moça Trevisani, Soledad Retamozo, Benedikt Hofauer, Andreas Knopf, G. Fraile, Roberto Giacomelli, Valérie Devauchelle‐Pensec, Alain Saraux, Stefano Bombardieri, Elisa Astorri, Fabiola Atzeni, Daniel Hammenfors, Johan G. Brun, Steven E. Carsons, B. Maure Noia, A. Filgueira, Tamer A. Gheita, Isabel Sánchez Berná, Miguel López-Dupla, R. Rojas, A M Febrer Nafria, Jérôme Morel, Eva Fonseca Aizpuru, Samuel Seoane, Pilar Brito‐Zerón, C. Morcillo, Sheila Melchor Díaz, Patrícia Carreira, Cristina Vollenveider, Marcos Vázquez, P Ericka Díaz Cuiza, B E Herrera, Sandra Consani, A Comotto, Borja de Miguel Campo, Belchin Kostov, Antoni Sisó‐Almirall, Belchin Kostov, Nihan Acar‐Denizli,
To characterize 414 patients with primary SS who developed haematological malignancies and to analyse how the main SS- and lymphoma-related features can modify the presentation patterns and outcomes.By January 2021, the Big Data Sjögren Project Consortium database included 11 966 patients fulfilling the 2002/2016 classification criteria. Haematological malignancies diagnosed according to the World Health Organization (WHO) classification were retrospectively identified.There were 414 patients (355 ...
Tópico(s): Salivary Gland Tumors Diagnosis and Treatment
2022 - Oxford University Press | Lara D. Veeken
S. Tehuacanero, R. Herrera, M. Ávalos‐Borja, Miguel José Yacamán,
Tópico(s): Electron and X-Ray Spectroscopy Techniques
1992 - Elsevier BV | Acta Metallurgica et Materialia
Borja de Miguel, G. Todd Pharr, Chuji Wang,
Feline aminopeptidase N (fAPN) has been shown to serve as a receptor for feline, canine, porcine and human coronaviruses. Our objective was to determine if fAPN can serve as a receptor for infectious bronchitis virus (IBV). Feline kidney cells that express fAPN and hamster kidney fibroblasts that do not express fAPN were inoculated with IBV and monitored for replication by indirect fluorescent assay and confocal microscopy and in chicken embryonated eggs. The results showed that the feline cells were ...
Tópico(s): Virus-based gene therapy research
2002 - Springer Science+Business Media | Archives of Virology
Ichiro Tsuda, Hiroshi Fujii, Satoru Tadokoro, Takuo Yasuoka, Yutaka Yamaguti,
... bursts in networks of coupled map neuronsGouhei Tanaka, Borja Ibarz, Miguel A. F. Sanjuan and Kazuyuki Aihara1 Mar 2006 | ...
Tópico(s): Nonlinear Dynamics and Pattern Formation
2004 - Imperial College Press | Journal of Integrative Neuroscience
Violeta Sicilia, Pilar Borja, Miguel Baya, José M. Casas,
Complexes [{Pt(bzq)(μ-C 7 H 4 NS 2 -κN,S)} 2 ] and [{Pt(bzq)(μ-C 7 H 4 NOS-κN,S)} 2 ] are two new selective colorimetric and turn-off phosphorescent chemosensors for Hg 2+ in DMSO–H 2 O solution.
Tópico(s): Luminescence and Fluorescent Materials
2015 - Royal Society of Chemistry | Dalton Transactions
Sandra Paola Viaña-Borja, Miguel Ortega‐Sánchez,
Due to the importance of coastline detection in coastal studies, different methods have been developed in recent decades in accordance with the evolution of measuring techniques such as remote sensing. This work proposes an automatic methodology with new water indexes to detect the coastline from different multispectral Landsat images; the methodology is applied to three Spanish deltas in the Mediterranean Sea. The new water indexes use surface reflectance rather than top-of-atmosphere reflectance ...
Tópico(s): Coastal wetland ecosystem dynamics
2019 - Multidisciplinary Digital Publishing Institute | Remote Sensing
Imanol Touzón, Vincenzo Nava, Borja de Miguel, V. Petuya,
This paper analyses the numerical outcome of applying three different well-known mooring design approaches to a floating wave energy converter, moored by means of four catenary lines. The approaches include: a linearized frequency domain based on a quasistatic model of the mooring lines, a time domain approach coupled with an analytic catenary model of the mooring system, and a fully coupled non-linear time domain approach, considering lines’ drag and inertia forces. Simulations have been carried ...
Tópico(s): Coastal and Marine Dynamics
2020 - Multidisciplinary Digital Publishing Institute | Journal of Marine Science and Engineering
Isabel Miralles, Rocío Soria, Manuel Esteban Lucas‐Borja, Miguel Soriano, Raúl Ortega,
This study analyzed the influence of biocrusts on the chemical properties and bacterial diversity and community composition in the underlying soils along a depth gradient (the biocrust (C1), middle (S2) and deep (S3) soil layers) in two semi-arid Mediterranean ecosystems. Organic carbon, pH, electric conductivity and calcium carbonate content were estimated by wet oxidation, potentiometrically (pHmeter), with a conductivity-meter and volumetrically with a Bernard calcimeter, respectively. Bacterial diversity ...
Tópico(s): Microbial Community Ecology and Physiology
2020 - Elsevier BV | The Science of The Total Environment
Antonio Lalueza, Jaime Lora‐Tamayo, C. de la Calle, Javier Sayas Catalán, Estíbaliz Arrieta, Guillermo Maestro de la Calle, Mikel Mancheño‐Losa, Álvaro Marchán-López, Raquel Díaz‐Simón, Rocío García-García, M. Catalán, Ana García‐Reyne, Borja de Miguel-Campo, Carlos Lumbreras,
El presente estudio retrospectivo observacional tiene como objetivo analizar la utilidad de las escalas SOFA (Sequential Organ Failure Assessment), qSOFA (Quick SOFA), NEWS (National Early Warning Score ) y Quick NEWS para predecir el fallo respiratorio y la muerte en pacientes con COVID-19 atendidos fuera de la Unidad de Cuidados Intensivos (UCI). Se incluyeron 237 adultos con COVID-19 hospitalizados seguidos durante un mes o hasta su fallecimiento. El fallo respiratorio se definió como un cociente PaO2/ ...
Tópico(s): Intensive Care Unit Cognitive Disorders
2020 - Elsevier BV | Revista Clínica Española
Cristina de la Calle, Antonio Lalueza, Mikel Mancheño‐Losa, Guillermo Maestro de la Calle, Jaime Lora‐Tamayo, Estíbaliz Arrieta, Ana García‐Reyne, Irene Losada, Borja de Miguel, Raquel Díaz‐Simón, Francisco López‐Medrano, Mario Fernández‐Ruiz, Octavio Carretero, Rafael San Juan, José María Aguado, Carlos Lumbreras,
The aim of our study was to elucidate if SARS-CoV-2 viral load on admission, measured by real-time reverse transcriptase–polymerase chain reaction (rRT-PCR) cycle threshold (Ct) value on nasopharyngeal samples, was a marker of disease severity. All hospitalized adult patients with a diagnosis of SARS-CoV-2 infection by rRT-PCR performed on a nasopharingeal sample from March 1 to March 18 in our institution were included. The study population was divided according to the Ct value obtained upon admission ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Springer Science+Business Media | European Journal of Clinical Microbiology & Infectious Diseases
Andreu Fernández‐Codina, Blanca Pinilla, Iago Pinal-Fernández, Iago Carballo, Carlos Feijoo-Massó, María Toledano‐Macías, Borja de Miguel-Campo, Eva Fonseca‐Aizpuru, Luis Sáez‐Comet, Miguel López-Dupla, José Hernández‐Rodríguez, Fernando Martínez‐Valle,
Several IgG4-related disease (IgG4-RD) phenotypes have been proposed and the first set of classification criteria have been recently created. Our objectives were to assess the phenotype distribution and the performance of the classification criteria in Spanish patients as genetic and geographical differences may exist.We performed a cross-sectional multicentre study (Registro Español de Enfermedad Relacionada con la IgG4, REERIGG4) with nine participating centres from Spain. Patients were recruited ...
Tópico(s): Neuroendocrine Tumor Research Advances
2020 - Oxford University Press | Lara D. Veeken
Ana M. Añazco-Guenkova, Borja Miguel‐López, Óscar Monteagudo-García, Raquel García-Vílchez, Sandra Blanco,
Abstract Recent advancements have illuminated the critical role of RNA modifications in post-transcriptional regulation, shaping the landscape of gene expression. This review explores how tRNA modifications emerge as critical players, fine-tuning functionalities that not only maintain the fidelity of protein synthesis but also dictate gene expression and translation profiles. Highlighting their dysregulation as a common denominator in various cancers, we systematically investigate the intersection ...
Tópico(s): RNA and protein synthesis mechanisms
2024 - Oxford University Press | NAR Cancer
Ana C. Durán, Miguel A. López‐Unzu, Cristina Rodrı́guez, Borja Fernández, Miguel Lorenzale, Andrea Linares, Francisca Salmerón, Valentín Sans‐Coma,
Abstract It was generally assumed that the ventricle of the primitive vertebrate heart was composed of trabeculated, or spongy, myocardium, supplied by oxygen‐poor luminal blood. In addition, it was presumed that the mixed ventricular myocardium, consisting of a compacta and a spongiosa, and its supply through coronary arteries appeared several times throughout fish evolution. Recent work has suggested, however, that a fully vascularized, mixed myocardium may be the primitive condition in gnathostomes. ...
Tópico(s): Ichthyology and Marine Biology
2015 - Wiley | Journal of Anatomy
R. Borja, Miguel de la Guárdia, Amparo Salvador, J.L. Burguera, M. Burguera,
Tópico(s): Advanced Chemical Sensor Technologies
1990 - Springer Science+Business Media | Fresenius Journal of Analytical Chemistry
Borja de Miguel, C Wang, William R. Maslin, R.W. Keirs, J R Glisson,
A total of 1300 birds in flock of breeder Pharaoh quail (Coturinix coturnix) experienced a moderate rate of mortality (13%) during a 7-day period. Clinical signs included depression, ruffled feathers, prostration, lameness, inapetence, diarrhea, and periorbital sinus swelling with mucoid discharge and lameness. Gross lesions observed in dead quail were emaciation, carcass congestion, mild hepatomegaly with green discoloration, congested intestinal mucosa, caseous purulent arthritis-osteomyelitis, ...
Tópico(s): Vector-borne infectious diseases
1998 - American Association of Avian Pathologists | Avian Diseases
Antonio Lalueza, Jaime Lora‐Tamayo, C. de la Calle, Javier Sayas Catalán, Estíbaliz Arrieta, Guillermo Maestro de la Calle, Mikel Mancheño‐Losa, Álvaro Marchán-López, Raquel Díaz‐Simón, Rocío García-García, M. Catalán, Ana García‐Reyne, Borja de Miguel-Campo, Carlos Lumbreras,
This observational retrospective study aimed to investigate the usefulness of Sequential Organ Failure Assessment (SOFA), Quick SOFA (qSOFA), National Early Warning Score (NEWS), and quick NEWS in predicting respiratory failure and death among patients with COVID-19 hospitalized outside of intensive care units (ICU). We included 237 adults hospitalized with COVID-19 who were followed-up on for one month or until death. Respiratory failure was defined as a PaO2/FiO2 ratio ≤200mmHg or the need for mechanical ...
Tópico(s): Intensive Care Unit Cognitive Disorders
2021 - Elsevier BV | Revista Clínica Española (English Edition)
C Wang, Borja de Miguel, F. W. Austin, R.W. Keirs,
Indirect fluorescent antibody (IFA) assay and reverse transcription-polymerase chain reaction (RT-PCR) are two current methods commonly used for the detection of infectious bronchitis virus (IBV) and its serotypes. The objectives of this study were to compare the two methods relative to detecting IBV in chicken embryos that were artificially inoculated with Mass41, Ark99, or Mass41/Ark99 in serial embryo passages and in tracheas and cecal tonsils collected from vaccinated commercial flocks with and ...
Tópico(s): Virus-based gene therapy research
1999 - American Association of Avian Pathologists | Avian Diseases
Cristina de la Calle, Francisco López‐Medrano, José L. Pablos, Jaime Lora‐Tamayo, Guillermo Maestro de la Calle, Marcos Sánchez-Fernández, Mario Fernández‐Ruiz, María Asunción Pérez‐Jacoiste Asín, José Manuel Caro‐Teller, Rocío García-García, M. Catalán, Joaquín Martínez‐López, Ángel Sevillano, Julia Origüen, M. Ripoll, Rafael San Juan, Antonio Lalueza, Borja de Miguel, Octavio Carretero, Fernando Aguilar-Rodríguez, Carlos F. Gómez, Estela Paz‐Artal, Héctor Bueno, Carlos Lumbreras, José María Aguado,
A subgroup of patients with SARS-CoV-2 infection was thought to have developed cytokine release syndrome and were treated with tocilizumab; however, a significant percentage of patients evolved. This study aimed to determine the usefulness of anakinra as a rescue treatment for patients with tocilizumab-refractory COVID-19 disease.A prospective cohort of patients with COVID-19 pneumonia who received anakinra as salvage therapy after failure of tocilizumab were compared (1:1) with selected controls ...
Tópico(s): Inflammasome and immune disorders
2021 - Elsevier BV | International Journal of Infectious Diseases
Rafael San Juan, Mario Fernández‐Ruiz, Francisco López‐Medrano, Octavio Carretero, Antonio Lalueza, Guillermo Maestro de la Calle, María Asunción Pérez‐Jacoiste Asín, Héctor Bueno, José Manuel Caro‐Teller, M. Catalán, Cristina de la Calle, Rocío García-García, Carlos F. Gómez, Rocío Laguna‐Goya, Manuel Lizasoaín, Joaquín Martínez‐López, Julia Origüen, Ángel Sevillano, Eduardo Gutiérrez, Borja de Miguel, Fernando Aguilar-Rodríguez, Patricia Parra, M. Ripoll, Tamara Ruiz-Merlo, Hernando Trujillo, José L. Pablos, Estela Paz‐Artal, Carlos Lumbreras, José María Aguado,
Controversy remains about the efficacy of tocilizumab (TCZ) for the treatment of severe COVID-19. We aimed to analyze the profile of TCZ-respondent patients.We retrospectively analyzed a cohort of patients with severe COVID-19 who received off-label TCZ after recommendation by a local committee and were admitted to the University Hospital "12 de Octubre" until May 2020. The primary end point was a significant clinical improvement (SCI) on day 14 after administration of TCZ. Factors independently related ...
Tópico(s): Long-Term Effects of COVID-19
2022 - Elsevier BV | International Journal of Infectious Diseases
Amparo Miguel, Mariano Linares, A Miguel, José M. Miguel-Borja,
Tópico(s): Inflammatory Biomarkers in Disease Prognosis
1988 - Karger Publishers | Acta Haematologica