Gerardo Guinto, Moisés Mercado, Miguel Abdo, Elisa Nishimura, Norma Aréchiga, Bárbara Nettel-Rueda,
Guinto, Gerardo MD; Mercado, Moises MD; Abdo, Miguel MD; Nishimura, Elisa MD; Aréchiga, Norma MD; Nettel, Barbara MD Author Information
Tópico(s): Amyloidosis: Diagnosis, Treatment, Outcomes
2007 - Lippincott Williams & Wilkins | Contemporary Neurosurgery
Daniel Zamora‐Valdés, Alan G. Contreras, Miguel Ángel Mercado,
Zamora-Valdés, Daniel MD; Contreras, Alan G. MD; Mercado, Miguel A. MD Author Information
Tópico(s): Esophageal and GI Pathology
2014 - Lippincott Williams & Wilkins | Journal of the American College of Surgeons
Viviana Soto‐Mercado, Miguel Mendivil‐Perez, Marlene Jiménez-Del-Río, Javier E. Fox, Carlos Velez‐Pardo,
T-cell acute lymphoblastic leukemia (T-ALL) is a highly heterogeneous malignant hematological disorder arising from T-cell progenitors. This study was aimed to evaluate the cytotoxic effect of CP55940 on human peripheral blood lymphocytes (PBL) and on T-ALL cells (Jurkat). PBL and Jurkat cells were treated with CP55940 (0−20 μM), and morphological changes in the cell nucleus/ DNA, mitochondrial membrane potential (ΔΨm), and intracellular reactive oxygen species levels were determined by fluorescence ...
Tópico(s): Epigenetics and DNA Methylation
2020 - Elsevier BV | Leukemia Research
Viviana Soto‐Mercado, Miguel Mendivil‐Perez, Marlene Jiménez-Del-Río, Carlos Velez‐Pardo,
Alzheimer's disease (AD) is characterized by structural damage, death, and functional disruption of cholinergic neurons (ChNs) as a result of intracellular amyloid-β (Aβ) aggregation, extracellular neuritic plaques, and hyperphosphorylation of protein tau (p-Tau) overtime.To evaluate the effect of the synthetic cannabinoid CP55940 (CP) on PSEN1 E280A cholinergic-like nerve cells (PSEN1 ChLNs)-a natural model of familial AD.Wild type (WT) and PSEN1 ChLNs were exposed to CP (1μM) only or in the presence of ...
Tópico(s): Biochemical effects in animals
2020 - IOS Press | Journal of Alzheimer s Disease
Viviana Soto‐Mercado, Miguel Mendivil‐Perez, Carlos Velez‐Pardo, Francisco Lopera, Marlene Jiménez-Del-Río,
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and cognitive disturbance as a consequence of the loss of cholinergic neurons in the brain, neuritic plaques and hyperphosphorylation of TAU protein. Although the underlying mechanisms leading to these events are unclear, mutations in presenilin 1 (PSEN1), e.g., E280A (PSEN1 E280A), are causative factors for autosomal dominant early-onset familial AD (FAD). Despite advances in the understanding of the physiopathology ...
Tópico(s): Mitochondrial Function and Pathology
2020 - Public Library of Science | PLoS ONE
Ana I. Álvarez‐Mercado, Miguel Navarro-Oliveros, Cándido Robles-Sánchez, Julio Plaza‐Díaz, María José Sáez‐Lara, Sergio Muñoz‐Quezada, Luis Fontana, Francisco Abadía‐Molina,
Specific microbial profiles and changes in intestinal microbiota have been widely demonstrated to be associated with the pathogenesis of a number of extra-intestinal (obesity and metabolic syndrome) and intestinal (inflammatory bowel disease) diseases as well as other metabolic disorders, such as non-alcoholic fatty liver disease and type 2 diabetes. Thus, maintaining a healthy gut ecosystem could aid in avoiding the early onset and development of these diseases. Furthermore, it is mandatory to evaluate ...
Tópico(s): Diet and metabolism studies
2019 - Multidisciplinary Digital Publishing Institute | Microorganisms
Dmitri Fabrikov, José Luis Guil‐Guerrero, María José González‐Fernández, Ignacio Rodríguez‐García, Francisco Gómez Mercado, Miguel Urrestarazu, María Teresa Lao, Miguel Ángel Rincón‐Cervera, Juan E. Álvaro, Svetlana Lyashenko,
Endemic Borago species contain notably high amounts of γ-linolenic acid (GLA, 18:3n6), the main bioactive fatty acid of borage oil. However, little is known about the occurrence of nutritionally relevant phytochemicals in seed oil of such plants. This work was designed to test the occurrence of important phytochemicals (tocopherols, sterols and squalene) in the seed oil of Borago species. To this end, seeds of endemic-wild and farmed Borago species were collected and analyzed. All compounds were analyzed ...
Tópico(s): Edible Oils Quality and Analysis
2019 - Elsevier BV | Journal of Food Composition and Analysis
C. Tomás, Ana M. Larrán, E. de Mercado, Miguel Ángel Sanz-Calvo, David Hernández, Berta Riaño, María Cruz García-González,
In the last decade substantial innovation in feeds has led to a significant reduction in fishmeal inclusion rates in feed for aquaculture. Nevertheless, to maintain the current growth of aquaculture, the demand of nutrient will increase at the same rate. So finding a sustainable alternative protein source to replace fish meal in fish feed continues being an important issue to supply the growing market demand of aquaculture products. This study has been conducted to examine the feasibility of partially ...
Tópico(s): Aquatic life and conservation
2018 - Elsevier BV | Aquaculture
Beatriz I. Fernández-Gil, Ahmed E. Abdel Moneim, Francisco Ortiz, Yingqiang Shen, Viviana Soto‐Mercado, Miguel Mendivil‐Perez, Ana Guerra‐Librero, Darío Acuña‐Castroviejo, Maria Micaela Molina‐Navarro, José Manuel García‐Verdugo, Ramy K. A. Sayed, Javier Florido, Juan de Dios Luna, Luís C. López, Germaine Escames,
Radiotherapy-induced gut toxicity is among the most prevalent dose-limiting toxicities following radiotherapy. Prevention of radiation enteropathy requires protection of the small intestine. However, despite the prevalence and burden of this pathology, there are currently no effective treatments for radiotherapy-induced gut toxicity, and this pathology remains unclear. The present study aimed to investigate the changes induced in the rat small intestine after external irradiation of the tongue, ...
Tópico(s): Oral health in cancer treatment
2017 - Public Library of Science | PLoS ONE
José Luis Guil‐Guerrero, Rebeca P. Ramos‐Bueno, Francisco Gómez Mercado, Miguel Ángel Rincón‐Cervera,
Abstract In this work, several oils and PUFA‐producing species have been analyzed to know the positional distribution of fatty acids within the triacylgycerol structure. Positional distribution was determined in terrestrial oils by means of enzymatic hydrolysis, while 13 C‐NMR was used for marine and processed oils, which contain long‐chain PUFA. In addition to several already known sources, other new ones have been characterized; i.e., α‐linolenic acid was high in the subcutaneous fat of Galician ...
Tópico(s): Lipid metabolism and biosynthesis
2014 - Wiley | European Journal of Lipid Science and Technology
Francisco Javier Molina‐Hidalgo, Antonio Rodríguez-Franco, Carmen Villatoro, Laura Medina‐Puche, José A. Mercado, Miguel Angel Galina Hidalgo, Amparo Monfort, José L. Caballero, Juan Muñoz‐Blanco, Rosario Blanco‐Portales,
Pectins are essential components of primary plant cell walls and middle lamellae, and are related to the consistency of the fruit and its textural changes during ripening. In fact, strawberries become soft as the middle lamellae of cortical parenchyma cells are extensively degraded during ripening, leading to the observed short post-harvest shelf life. Using a custom-made oligonucleotide-based strawberry microarray platform, a putative rhamnogalacturonate lyase gene (FaRGlyase1) was identified. Bioinformatic ...
Tópico(s): Plant Physiology and Cultivation Studies
2013 - Oxford University Press | Journal of Experimental Botany
Kimon Divaris, Ana Cristina Mafla, Laura Villa‐Torres, Marisol Sánchez-Molina, Clara Liliana Gallego Gómez, Luis Fernando Vélez-Jaramillo, Julián Andrés Tamayo-Cardona, David Pérez-Cepeda, Martha Ligia Vergara-Mercado, Miguel Simancas‐Pallares, Argy Polychronopoulou,
Links between the demanding nature of studies in the health sciences, students' personality traits and psychological distress have been well-established. While considerable amount of work has been done in medicine, evidence from the dental education arena is sparse and data from Latin America are lacking. The authors conducted a large-scale investigation of psychological distress among dental students in Colombia and sought to determine its curriculum and student-level correlates. The Spanish version ...
Tópico(s): Innovations in Medical Education
2013 - BioMed Central | BMC Medical Education
Esther Guadalupe Corona-Sánchez, José Francisco Muñoz‐Valle, Laura González-López, Julia Dolores Sanchez-Hernandez, Mónica Vázquez-Del Mercado, Heriberto Ontiveros-Mercado, Miguel Huerta, Xóchitl Trujillo, Alberto Daniel Rocha-Muñoz, Alfredo Celis, Ricardo Ortega-Flores, Jorge Iván Gámez-Nava,
Tópico(s): Psoriasis: Treatment and Pathogenesis
2011 - Springer Science+Business Media | Rheumatology International
Rafael Sesmero, John R. Mitchell, José A. Mercado, Miguel A. Quesada,
The present study is focused on the characteristics of juice made from transgenic strawberry fruits with a 90% reduction on pectate lyase mRNA expression. No differences of soluble solids, pH or solid volume fraction were found between control and transgenic juices. Total sugar content of the serum fraction was also similar but a slightly higher content of large molecular mass polyuronides was observed in transgenic juice. The solid fraction of transgenic juice contained larger particles than did ...
Tópico(s): Postharvest Quality and Shelf Life Management
2009 - Elsevier BV | Food Chemistry
Nieves Santiago‐Dómenech, S. Jimenez-Bemudez, Antonio J. Matas, Jocelyn K. C. Rose, Juan Muñoz‐Blanco, José A. Mercado, Miguel A. Quesada,
Cell wall disassembly in softening fruits is a complex process involving the cumulative action of many families of wall-modifying proteins on interconnected polysaccharide matrices. One strategy to elucidate the in vivo substrates of specific enzymes and their relative importance and contribution to wall modification is to suppress their expression in transgenic fruit. It has been reported previously that inhibiting the expression of pectate lyase genes by antisense technology in strawberry (Fragaria ...
Tópico(s): Plant Reproductive Biology
2008 - Oxford University Press | Journal of Experimental Botany
Juliana Gil, Paula Pavía, Marleny Montilla, Astrid C. Florez, Claudia Quintero, Marcela Mercado, Miguel Vacca, Santiago Nicholls, Concepción J. Puerta,
Diagnosis of Chagas disease in its latent and chronic phase is difficult because of the low parasitemia levels. Therefore, serological and molecular techniques are necessary to achieve an appropriate diagnosis.The polymerase chain reaction based on the amplification of the SIRE element inserted into H2A encoding genes was compared with classical serological tests for the diagnosis of Chagas disease in Colombian patients.An agreement study was carried out by comparing the PCR with ELISA (enzyme linked ...
Tópico(s): Synthesis and Biological Evaluation
2007 - National Institute of Health | Biomédica
Albert Premkumar, José A. Mercado, Miguel A. Quesada,
The levels of two subunits of chloroplast ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco), total soluble proteins, carbon and leaf nitrogen content, and photosynthetic pigments in various plants (avocado, oak, olive, and strawberry) grown in vitro and ex vitro were analysed. Compared to ex vitro grown plants, micropropagated avocado, oak, and strawberry showed a markable decrease in large subunit Rubisco. However, the small subunit only decreased in strawberry and oak. Contrary to this, ...
Tópico(s): Plant tissue culture and regeneration
2001 - Elsevier BV | Journal of Plant Physiology
Eva Domínguez, José A. Mercado, Miguel A. Quesada, Antonio Heredia,
Tópico(s): Photosynthetic Processes and Mechanisms
1999 - Springer Science+Business Media | Sexual Plant Reproduction
Eva Domínguez, José A. Mercado, Miguel A. Quesada, Antonio Heredia,
We report the use of anhydrous hydrogen fluoride as a new procedure to extract intact exine from a range of species. Pollen samples were incubated in anhydrous HF in pyridine for 5 hours at 40°C. Exines were recovered after several washes in water and ethanol. The quality of the exine obtained by this method has been followed by SEM micrographs and FT‐IR spectroscopy. The morphology of the pollen grains as determined by SEM was maintained after hydrogen fluoride treatment. FT‐IR spectra revealed ...
Tópico(s): Photosynthetic Processes and Mechanisms
1998 - Taylor & Francis | Grana
José A. Mercado, Miguel Ángel Ladero Quesada, Michael S. Reid, Victoriano Valpuesta, Marita Cantwell,
1995 - International Society for Horticultural Science | Acta Horticulturae
Stephen A. Poon, Carl K. Gjertson, Miguel Ángel Mercado, Peter M. Raimondi, Kristin Kozakowski, Kenneth I. Glassberg,
... Managed Expectantly Stephen A. Poon, Carl K. Gjertson, Miguel A. Mercado, Peter M. Raimondi, Kristin A. Kozakowski, and Kenneth ... Connecticut 06030-3955. More articles by this author Miguel A. Mercado More articles by this author Peter M. Raimondi ...
Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
2009 - Lippincott Williams & Wilkins | The Journal of Urology
Viviana Soto‐Mercado, Miguel Mendivil‐Perez, Carlos Velez‐Pardo, Marlene Jiménez-Del-Río,
Alzheimer’s disease (AD) is a complex neurodegenerative disease characterized by functional disruption, death of cholinergic neurons (ChNs) because of intracellular and extracellular Aβ aggregates, and hyperphosphorylation of protein TAU (p-TAU). To date, there are no efficient therapies against AD. Therefore, new therapies for its treatment are in need. The goal of this investigation was to evaluate the effect of the polyphenol epigallocatechin-3-gallate (EGCG) on cholinergic-like neurons (ChLNs) bearing ...
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2021 - Multidisciplinary Digital Publishing Institute | Biomolecules
Jason Van Batavia, Angela M. Fast, Shannon N. Nees, Miguel Ángel Mercado, Anthony Gaselberti, Kenneth I. Glassberg,
... Van Batavia, Angela M. Fast, Shannon N. Nees, Miguel A. Mercado, Anthony Gaselberti, and Kenneth I. Glassberg Jason P. ... Shannon N. Nees More articles by this author Miguel A. Mercado Current address: Department of Urology, Baylor College of ...
Tópico(s): Urologic and reproductive health conditions
2013 - Lippincott Williams & Wilkins | The Journal of Urology
Miguel Ángel Mercado, Alexandra Rueda de Leon, J. Cisneros-Correa,
Mercado, Miguel A. MD; Rueda De Leon, Alexandra MD; Cisneros-Correa, Julio MD Author Information
Tópico(s): Oral and gingival health research
2020 - Lippincott Williams & Wilkins | Journal of the American College of Surgeons
Mario Hidalgo‐Ruiz, Susana Mejia-López, Rosa Martha Pérez‐Serrano, Guadalupe Zaldívar‐Lelo de Larrea, Sabrina Ganzinelli, Mónica Florin‐Christensen, Carlos E. Suárez, Rubén Hernández-Ortíz, Miguel Mercado-Uriostegui, Angelina Rodríguez, Bertha Isabel Carvajal-Gamez, Minerva Camacho-Nuez, Silvina Elizabeth Wilkowsky, Juan Mosqueda,
Tópico(s): vaccines and immunoinformatics approaches
2022 - Elsevier BV | Vaccine
Jorge Manuel Mercado–Colmenero, Miguel Ángel Rubio–Paramio, M. Dolores La Rubia, David Lozano-Arjona, Cristina Martín–Doñate,
Tópico(s): Innovations in Concrete and Construction Materials
2019 - Springer Science+Business Media | The International Journal of Advanced Manufacturing Technology
Jorge Manuel Mercado–Colmenero, Miguel Ángel Rubio–Paramio, F. Guerrero-Villar, Cristina Martín–Doñate,
This paper presents the numerical-experimental study carried out on a new rotor adapted from a Savonius rotor. Aesthetic, ergonomic and functional requirements have been incorporated into it in order to be part of sustainable consumer products. The new rotor consists of a parametric model adaptable to the dimensions and geometry of the products which it will be part of. A set of translation, symmetry, rotation and scaling operations have been applied to the bucket sections of the Savonius rotor ...
Tópico(s): Aerospace Engineering and Energy Systems
2018 - Elsevier BV | Energy Conversion and Management
Jorge Manuel Mercado–Colmenero, Miguel Ángel Rubio–Paramio, Peter Karlinger, Cristina Martín–Doñate,
Tópico(s): Additive Manufacturing and 3D Printing Technologies
2018 - Springer Science+Business Media | The International Journal of Advanced Manufacturing Technology
Mario Hidalgo‐Ruiz, Carlos E. Suárez, Miguel Mercado-Uriostegui, Rubén Hernández-Ortíz, Juan Alberto Ramos, Edelmira Galindo‐Velasco, Gloria León-Ávila, José Manuel Hernández, Juan Mosqueda,
Babesia bovis belongs to the phylum Apicomplexa and is the major causal agent of bovine babesiosis, the most important veterinary disease transmitted by arthropods. In apicomplexan parasites, the interaction between AMA1 and RON2 is necessary for the invasion process, and it is a target for vaccine development. In B. bovis, the existence of AMA1 has already been reported; however, the presence of a homolog of RON2 is unknown. The aim of this study was to characterize RON2 in B. bovis.The B. bovis ...
Tópico(s): vaccines and immunoinformatics approaches
2018 - BioMed Central | Parasites & Vectors
Jorge Manuel Mercado–Colmenero, Miguel Ángel Rubio–Paramio, Juan de Juanes Marquez-Sevillano, Cristina Martín–Doñate,
This paper presents a new method for the automatic design of the cooling system in injection molds, based on the discrete geometry of the plastic part. In a first phase the new algorithm recognizes the discrete topology of the part, obtaining its depth map and detecting flat, concave regions and slender details which are difficult to cool. The algorithm performs an automatic analysis of the heat transfer, taking into account functional parameters, in order to guarantee a uniform cooling of the part. ...
Tópico(s): Additive Manufacturing and 3D Printing Technologies
2018 - Elsevier BV | Computer-Aided Design