... In recent years, however, lead singer and songwriter Mikael Åkerfeldt has abandoned death-metal growls and metal riffs ...
Tópico(s): Cultural Industries and Urban Development
2018 - Springer Science+Business Media | International Journal of the Sociology of Leisure
Tord Berggård, Simona Miron, Patrik Önnerfjord, Eva Thulin, Karin S. Åkerfeldt, Jan J. Enghild, Mikael Akke, Sara Linse,
Calbindin D 28k is a member of the calmodulin superfamily of Ca 2+ -binding proteins and contains six EF-hands. The protein is generally believed to function as a Ca 2+ buffer, but the studies presented in this work indicate that it may also act as a Ca 2+ sensor. The results show that Mg 2+ binds to the same sites as Ca 2+ with an association constant of ∼1.4·10 3 m −1 in 0.15 m KCl. The four high affinity sites in calbindin D 28k bind Ca 2+ in a non-sequential, parallel manner. In the presence of ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2002 - Elsevier BV | Journal of Biological Chemistry
Lluís Pérez, Eva-Lis Odenberger, Mikael Schill, Fredrik Niklasson, Pia Åkerfeldt, Mats Oldenburg,
Abstract The demands associated with the production of advanced parts made of nickel-base superalloys are continuously increasing to meet the requirements of current environmental laws. The use of lightweight components in load-carrying aero-engine structures has the potential to significantly reduce fuel consumption and greenhouse gas emissions. Furthermore, the competitiveness of the aero-engine industry can benefit from reduced production costs and shorter development times while minimizing costly ...
Tópico(s): Microstructure and Mechanical Properties of Steels
2021 - Springer Science+Business Media | International Journal of Material Forming
Petra Behnen, Elizabeth A. Olmsted‐Davis, Erin Delaney, Birgitta Frohm, Mikael C. Bauer, Tommy Cedervall, David O’Connell, Karin S. Åkerfeldt, Sara Linse,
Ribosomes are the protein factories of every living cell. The process of protein translation is highly complex and tightly regulated by a large number of diverse RNAs and proteins. Earlier studies indicate that Ca(2+) plays a role in protein translation. Calmodulin (CaM), a ubiquitous Ca(2+)-binding protein, regulates a large number of proteins participating in many signaling pathways. Several 40S and 60S ribosomal proteins have been identified to interact with CaM, and here, we report that CaM binds ...
Tópico(s): Peptidase Inhibition and Analysis
2012 - American Chemical Society | Biochemistry
David O’Connell, Mikael C. Bauer, John O’Brien, Winifred M. Johnson, Catherine A. Divizio, Sara L. O’Kane, Tord Berggård, Alejandro Merino, Karin S. Åkerfeldt, Sara Linse, Dolores J. Cahill,
Calmodulin is an essential regulator of intracellular processes in response to extracellular stimuli mediated by a rise in Ca(2+) ion concentration. To profile protein-protein interactions of calmodulin in human brain, we probed a high content human protein array with fluorophore-labeled calmodulin in the presence of Ca(2+). This protein array contains 37,200 redundant proteins, incorporating over 10,000 unique human neural proteins from a human brain cDNA library. We designed a screen to find high ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2010 - Elsevier BV | Molecular & Cellular Proteomics