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Jonathan Northcroft, Kevin Dunn, Tracey Boles, Slobhan Maguire, Hala Jaber, Waldemar Januszczak, Simon Dickson, John Dugdale, William Kay, Ed Wright, Barbara Hall, Mark Francheti, Nigel Botherway, Barry Lloyd, Gary Portugal, Fred Redwood, Jim Munro, Jon Swain, Sally Brock, Helen Davies, James Brabazon, Trish Lorenz, Rob Hughes, Jason Dawe, John Peter, Colin Scott, Anthony Rhodes, Andrew Longmore, John Waples Business Editor, Lesley White, Michael Carey, Godfrey Holmes, Terry Hope, Gareth Walsh, George Dearsley, Ivo Tennant, Rachel de Thame, Kathryn Cooper, Paul Marinko, P D, David Smith, David Cracknell Political Editor, Eric Nicoli Chairman, Neil Wormald, E P, Cherry Dewey, Clive Davis, Karen Robinson, Martin Jol, Joseph Dunn, Tony Allen-Mills, Martin James, Ariel Leve, Nirpal Singh Dhaliwal, Lord Jacobs, Dipesh Gadher Transport Correspondent, Irwin Stelzer, Adrian Furnham, Peter B Hayward, Peter Wilson, Rosie Millard, Christine Lamb, Graham Rice, Norman, Christopher Hart, Stuart Barnes, Liam O'Sullivan, Jason Webster, H C, Mangal Kapoor, Mike Ryan, Bryan Ferry, Cally Law, Paul Forsyth, Hugh Canning, Isabel Oakeshott, Ian Harkness, Andrew Stone, Jeremy Clarkson, David Cairns, Elizabeth Gow, Victoria Segal, Nicola Smith, Giles Chapman, Michael Portillo, Jim Massey, Lawrence James, Richard Newton, James Brewer, Sarah Dempster, Dave Pollard, Tim Collins, Robert Pires, Richard Fletcher, Susie Boyt, Simon Rogerson, Madeleine Shaer, Jeff Potter, Sarah-Kate Templeton Health Correspondent, Helen McCormack, Colin McDonald, Trefor Llewelyn Davies, Laurence Williams, John Thompson, Stuart Wavell, Paul Donovan, Keith Turner, Simon Hawkesworth, Chris Woodhead, Jasper Gerard, Paul Driver, Iain Miller, Ian Hawkey, Shelley Von Strunckel, Christopher Morgan, Stephen Anderton, Paul Durman, Tim Rayment, Mark Edwards, Charles Levinson, Claran Maher, David Linley, Jesse Norman, Ken Livingstone, Hugh McLlvanney, Nick Rodrigues, Keith Dodsworth, Ayesha Hudson, Heston Blumenthal, Judith Hamilton, Andrew Motion, Hugo Barnacle, Bob Caldwell, Christina Lamb, Sharon Edwards, Bob Graham, Christopher Silverster, Raymond Keene, C L, Rod Liddle, Douglas Alexander, David Cracknell, Cosmo Landesman, Kevin Kerrigan managing director, David Walton, Diana Wright, Christine Mead, Tom Wright, Emma Smith, Stephen Jones, Dominic O'Connell, Andrew Holgate, Barry Flatman, Brian Deer, Louise Armitstead, Colin Page, Oliver James, Amanda Blinkhorn, Caroline Donald, Robert Whelan Deputy Director, Tiffanie Darke, Talib Choudhry, Mervyn, Graham Long, Bryan Appleyard, Andrew Kirby, John Elliott, Isabel Oakeshott Deputy Political Editor, Mark Anstead, Mark Stucklin, Richard Woods, Roland White, Hugh Carthy, Steven Swinford, Mark Palmer, Shane Watson, Abul Taher, Maurice Chittenden, Maurice Fitzpatrick senior tax manager, Richard Brooks Arts Editor, Richard Rae, Mark Franchetti, Lisa Smith, Jon Ungoed-Thomas, Jonathan Leake, Katharine Hibbert, M E, Michael Sheridan, Clare Francis, Michael Smith, John Harlow, Simon Brooke, Dipesh Gadher, Mark Kleinman, John Waples, Des MacHale, Peter O'Reilly, Matthew Campbell, Brian Glanville, Daniel Foggo, Gemma Soames, Simon Jenkins, Stephen Pettitt, Julie Wright, Rory MacLean, Will Iredale, Jonathan Milne, Jessica Bown, Sigrid Morrison, Suzanne Portnoy, David Cameron, Sally Kinnes, Eric Sykes, Sophie Harrison, Brian Doogan, John Aizlewood, Minette Marrin, Clifford Bishop, James Wurzburger, Andrew Frankel, Graham Norwood, Anastasia de Waal, Joe Lovejoy, Jonathan Futrell, P W, Rachel Newsome, Hugh Pearman, Dan Cairns, Ed Habershon, Julian Ryal, Huw Beynon, David Smith Economics Editor, Neil Hanson, Alex Bellos, Malise Ruthven, Joanna Simon, Matthew Goodman, India Knight, Simon Wilde Cricket Correspondent, Kevin Osborne, Dominic Rushe, Micheal Smith, Gary Martin, Helen Stewart,

... post divorce looking for sex One day, Suzanne Portnoy looked in the mirror and saw she'd ...

2006 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Sharon Portnoy, Mike Seed, John G. Sled, Christopher K. Macgowan,

Purpose We propose an analytical method for calculating blood hematocrit ( Hct ) and oxygen saturation ( sO 2 ) from measurements of its T 1 and T 2 relaxation times. Theory Through algebraic substitution, established two‐compartment relationships describing and as a function of hematocrit and oxygen saturation were rearranged to solve for Hct and sO 2 in terms of R 1 and R 2 . Resulting solutions for Hct and sO 2 are the roots of cubic polynomials. Methods Feasibility of the method was established by comparison ...

Tópico(s): MRI in cancer diagnosis

2017 - Wiley | Magnetic Resonance in Medicine

Jornais Acesso aberto

Bruce Bernard, Nicholas Watt Chief Ireland Correspondent, Simon Pepper, John Naughton, Lynne Greenwood, Brendan Martin, Sue Baker, Paul Heiney, Nick Nuttall, John Padden, Patricia Davies, Adrian Lee, Grace Bradberry, Victor Serebriakoff, Jane MacQuitty, Simon Barnes, Bill Frost, Peter Sutton, Alexandra Frean, Media Correspondent, Mark Souster, J. D. Evans, John Diamond, Ivo Tennant, Tony Turnbull, Philip Howard, Michael Plumbe, Chairman, G. V. S. Bucknall, William M. Ballantine, Clive Davis, Nicholas Watt, Chief Ireland Correspondent, Emma Wilkins and John O'leary, Simon Wilde, J. C., Tom Walker, Kevin Eason, Clare Stewart, Robert Miller, Giles Coren, Jonathan Prynn, Transport Correspondent, Martin Fletcher, Margaret Totterdell, Pat Gibson, Robert Sheehan, John Redwood, Hugh Douglas, Peter Capella, Ross Dunn and Christopher Walker, Peter Ball, John McLeod, John Lanchester, Jason Niss?, Ian Morton, Robin Young, Michael Cutler, Peter Millar, Kenneth Mole, Michael Clark, James Landale Political Reporter, Frances Bissell, Quentin Letts, A. H. Green, B. M. M. Hardisty, Les Evans and David Long, Anna Blundy, Jason Nissë, Katherine Baker, Donald Simpson, Peter Barnard, Nicholas Wapshott, Ros Drinkwater, Derwent May, Kate Muir, Patricia Tehan, Banking Correspondent, Alan Hamilton and Stewart Tendler, Lizanne Rose, Russell Kempson, Nigel Williamson, Stephen Anderton, Sarah Johnson, Audrey Magee, Ireland Correspondent, and Michael Kallenbach, Eliza Pakenham, David Miller, Susan Pape, George Plumptre, Michael Hardern Director, Robert Barnard, Christina Koning, Dalya Alberge, Arts Correspondent, J. Griffin, S. Darken, John O'leary, Education Editor, and Andrew Pierce, Raymond Keene, Jonathan Prynn, Ron Sandler, Christine Buckley, Gareth Huw Davies, David Robinson, Leyla Linton, Karen Zagor, Paul Wilkinson, P. H. S, James Allcock, Harriet Paterson, Janet Bush and Robert Miller, Nigel Hawkes, Caroline Merrell, Eric Reguly, Richard Owen, Sara Mcconnell, David Powell, Athletics Correspondent, Oliver Holt, Marcel Berlins, Roger Boyes, Jeremy Paxman, John Gummer, Erica Wagner, Oliver August, John Haldane, Julian Muscat, Marc Jordan, Richard E. Grant, Joanna Pitman, Jack Crossley, Guy Walters, Sara McConnell, Rob Hughes, Football Correspondent, Christopher Walker, James Pringle, Alan Copps, Jonathan Palmer, Adam Fresco and Frances Gibb, Mel Webb, Craig Lord, Paul Divine, Gillian Bowditch, Scotland Correspondent, and Stephen Farrell, Richard Owen Rome Correspondent, A. Brockbank, Bill Jones, Gabrielle Gill, Tim Wapshott, Helen Mound, Helen Pridham, Nicholas Marston, Mark Twells, Alan Lee Cricket Correspondent, Richard Beeston, Jane Laidlaw, Nick Nuttall, Environmental Correspondent, Ben Macintyre, Graham Searjeant, Simon Jenkins, Hattie Ellis, Tim Jones, Kate Bassett, Stuart Birch, Tom Rhodes, Jonathan Meades, Marianne Curphey, Jill Crawshaw, Richard Morrison, Jack Bailey, Stuart Housden Director, Douglas Dow Director, Elizabeth Buchan, Michael Henderson, Fiona Beckett, Alasdair Murray, Jenny Macarthur, Dr Dashboard, Paul Richardson, John Reeve, Marianne Curphey and Caroline Merrell, Walter Ellis, David Long, Colin McQuillan, Mike Rosewell, Rowing Correspondent, Gill Hornby, Jonathan Mirsky, Christopher Irvine, Taras Grescoe,

... and Warrior By Valerie Windsor Viking, £13.50 Portnoy minor Plains talking Mystery Ride By Robert Boswell ...

1996 - Gale Group | TDA

Artigo Revisado por pares

В. В. Кузин, Sergey N. Grigoriev, M. Yu. Fedorov, Mike Portnoy, V. N. Ermolin,

Technological features of pulsed laser machining of yttriastabilized tetragonal zirconia polycrystal (Y-TZP) were studied. The connection between the laser power, scanning speed, laser beam steps and surface state of zirconia ceramic was established. The results of the research showed that pulsed laser machining of this material is an effective tool to control surface modification process and presents an attractive alternative to conventional techniques.

Tópico(s): Advanced machining processes and optimization

2015 - Trans Tech Publications | Applied Mechanics and Materials

Artigo Revisado por pares

В. В. Кузин, Sergey N. Grigoriev, Mike Portnoy,

The typical defect based on the experimental study of the ceramic surfaces was defined. Finite element numerical model was used to compute stresses which develop in the ceramic surface layer with single typical defect under the action of thermal loading. The relationship between heat flow and stresses in the defective surface layer of oxide ceramics is identified.

Tópico(s): Advanced ceramic materials synthesis

2016 - Trans Tech Publications | Applied Mechanics and Materials

Artigo Revisado por pares

Sharon Portnoy, Natasha Milligan, Mike Seed, John G. Sled, Christopher K. Macgowan,

To characterize the magnetic susceptibility and relaxation times (T1 and T2 ) of fetal blood at 3 T as a function of the hematocrit (Hct) and oxygen saturation (sO2 ).Susceptibility and relaxometry measurements were performed on cord blood specimens (N = 90, derived from six caesarean deliveries) with a range of hematocrits and oxygen saturations (0.09 < Hct < 0.82, 7 < sO2 < 100%). To obtain simple, analytic relationships between MRI properties and blood properties, data were fit to established two-compartment (plasma ...

Tópico(s): Cardiovascular Function and Risk Factors

2017 - Wiley | Magnetic Resonance in Medicine

Artigo Acesso aberto Revisado por pares

Sharon Portnoy, Mark Osmond, Meng Yuan Zhu, Mike Seed, John G. Sled, Christopher K. Macgowan,

To characterize the MRI relaxation properties of human umbilical cord blood at 1.5 Tesla.Relaxometry measurements were performed on cord blood specimens (N = 88, derived from six caesarean deliveries) spanning a broad range of hematocrits (Hct = 0.19-0.76) and oxygen saturations (sO2 = 4-100%), to characterize the dependence of T1 and T2 on these blood properties. Adult blood data (N = 31 specimens, derived from two volunteers) were similarly studied to validate our experimental methods by comparison with existing ...

Tópico(s): Advanced NMR Techniques and Applications

2016 - Wiley | Magnetic Resonance in Medicine

Artigo Revisado por pares

Ditte Staub Jørgensen, Niels Vejlstrup, Line Rode, C. K. Ekelund, Christopher K. Macgowan, Lisa Neerup Jensen, Lone Nikoline Nørgaard, Sharon Portnoy, Mike Seed, Karin Sundberg, Kirsten Søgaard, Julie Lyng Forman, Ann Tabor,

<b><i>Introduction:</i></b> The false-positive rate in the prediction of fetal anemia is 10–15%. We investigated if a new, noninvasive MRI method used as a supplement to ultrasound could improve the prediction. <b><i>Methods:</i></b> Fetuses suspected of anemia and controls were scanned in a 1.5-tesla MRI scanner 1–4 times during pregnancy. Cases were scanned before and after intrauterine blood transfusion with a T1-mapping MRI sequence in a cross-section ...

Tópico(s): Parvovirus B19 Infection Studies

2019 - Karger Publishers | Fetal Diagnosis and Therapy

Artigo Revisado por pares

В. В. Кузин, M. Yu. Fedorov, Predrag Dašić, Mike Portnoy,

Modelling is necessary for the control of exploitation process of ceramic details to achieve improved reliability and high productivity. Of most importance in exploitation of nitride ceramic details is the establishment of models that relates external loading with stress-strain state through consideration of mechanical and thermal interactions between the ceramic structural elements. This paper evaluates several interrelationships between heat flow and stress inhomogeneity in nitride ceramics which ...

Tópico(s): Advanced materials and composites

2015 - Trans Tech Publications | Applied Mechanics and Materials

Artigo Revisado por pares

Jiawei Xu, An Qi Duan, Davide Marini, Jessie Mei Lim, Johannes Keunen, Sharon Portnoy, John G. Sled, Brian W. McCrindle, John‏ Kingdom, Christopher K. Macgowan, Mike Seed,

Doppler ultrasound measurements of the peak systolic velocity of the middle cerebral artery can be used to noninvasively diagnose fetal anemia but are less precise following fetal blood transfusion and in late gestation. We have previously demonstrated the feasibility of estimating fetal hematocrit in vitro using magnetic resonance imaging relaxation times. Here we report the use of magnetic resonance imaging as a noninvasive tool to accurately detect fetal anemia in vivo.This study has 2 objectives: ( ...

Tópico(s): Fetal and Pediatric Neurological Disorders

2019 - Elsevier BV | American Journal of Obstetrics and Gynecology

Revisão Revisado por pares

Liqun Sun, Christopher K. Macgowan, Sharon Portnoy, John G. Sled, Shi‐Joon Yoo, Lars Grosse‐Wortmann, Edgar Jaeggi, John‏ Kingdom, Mike Seed,

Until recently, our modern understanding of fetal circulatory physiology has been largely based on invasive measurements made in fetal sheep. However, new MRI technology developed by our group has provided equivalent information about the distribution of blood flow and oxygen transport noninvasively. The initial findings largely confirm prior estimates about the human fetal circulation extrapolated from fetal sheep data and human ultrasound data. Here we describe the hemodynamics of the normal late ...

Tópico(s): Congenital Heart Disease Studies

2017 - Wiley | Echocardiography

Artigo Revisado por pares

Meng Yuan Zhu, Natasha Milligan, Sarah Keating, Rory Windrim, Johannes Keunen, Varsha Thakur, Annika Öhman, Sharon Portnoy, John G. Sled, Edmond Kelly, Shi‐Joon Yoo, Lars Gross-Wortmann, Edgar Jaeggi, Christopher K. Macgowan, John‏ Kingdom, Mike Seed,

Background Late-onset intrauterine growth restriction (IUGR) results from a failure of the placenta to supply adequate nutrients and oxygen to the rapidly growing late-gestation fetus. Limitations in current monitoring methods present the need for additional techniques for more accurate diagnosis of IUGR in utero. New magnetic resonance imaging (MRI) technology now provides a noninvasive technique for fetal hemodynamic assessment, which could provide additional information over conventional Doppler ...

Tópico(s): Fetal and Pediatric Neurological Disorders

2015 - Elsevier BV | American Journal of Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

Liqun Sun, Joshua van Amerom, Davide Marini, Sharon Portnoy, Fu‐Tsuen Lee, Brahmdeep S. Saini, Jessie Mei Lim, Julien Aguet, Edgar Jaeggi, John‏ Kingdom, Christopher K. Macgowan, Steven P. Miller, Guoying Huang, Mike Seed,

To characterize, using magnetic resonance imaging (MRI), the distribution of blood flow and oxygen transport in human fetuses with subtypes of congenital heart disease (CHD) that present with neonatal cyanosis.Blood flow was measured in the major vessels of 152 late-gestation human fetuses with CHD and 40 gestational-age-matched normal fetuses, using cine phase-contrast MRI. Oxygen saturation (SaO2 ) was measured in the major vessels of 57 fetuses with CHD and 40 controls.Compared with controls, we found ...

Tópico(s): Congenital Diaphragmatic Hernia Studies

2021 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

Brahmdeep S. Saini, Jack R. T. Darby, Davide Marini, Sharon Portnoy, Mitchell C. Lock, Jia Yin Soo, Stacey L. Holman, Sunthara Rajan Perumal, Rachel M. Wald, Rory Windrim, Christopher K. Macgowan, John‏ Kingdom, Janna L. Morrison, Mike Seed,

Human placental function is evaluated using non-invasive Doppler ultrasound of umbilical and uterine artery pulsatility indices as measures of resistance in placental vascular beds, while measurement of placental oxygen consumption ( VO2 ) is only possible during Caesarean delivery. This study shows the feasibility of using magnetic resonance imaging (MRI) in utero to measure blood flow and oxygen content in uterine and umbilical vessels to calculate oxygen delivery to and VO2 by the gravid uterus, uteroplacenta ...

Tópico(s): Prenatal Screening and Diagnostics

2021 - Wiley | The Journal of Physiology

Artigo Acesso aberto Revisado por pares

Brahmdeep S. Saini, Jack R. T. Darby, Sharon Portnoy, Liqun Sun, Joshua van Amerom, Mitchell C. Lock, Jia Yin Soo, Stacey L. Holman, Sunthara Rajan Perumal, John‏ Kingdom, John G. Sled, Christopher K. Macgowan, Janna L. Morrison, Mike Seed,

Key points Human fetal Doppler ultrasound and invasive blood gas measurements obtained by cordocentesis or at the time of delivery reveal similarities with sheep (an extensively used model for human fetal cardiovascular physiology). Oxygen saturation (SO 2 ) measurements in human fetuses have been limited to the umbilical and scalp vessels, providing little information about normal regional SO 2 differences in the fetus. Blood T2 MRI relaxometry presents a non‐invasive measure of SO 2 in the major fetal ...

Tópico(s): Pregnancy and preeclampsia studies

2020 - Wiley | The Journal of Physiology

Artigo Acesso aberto Revisado por pares

Neil McIntosh, Sara Portnoy, Mike Berger, Helena Crockford, P Hamilton,

A randomised double blind study of 2 PAA solutions given to 64 neonates showed better survival and more normal plasma aminograms in the group receiving M (McIntosh 8 Mitchell 1990). 23 on M and 25 on V completed the study. At 3 years (range 2.5-3.5) 32 survivors were identified (19 M, 13 V). 17 M and 10 V were psychometrically tested without knowledge of the original course of illness or aminoacid regimen. (2 M and 2 V could not be obtained for testing and 1 V infant was untestable). 2 of 17 M and 4 ...

Tópico(s): Metabolism and Genetic Disorders

1991 - Springer Nature | Pediatric Research

Artigo Revisado por pares

В. В. Кузин, Sergey V. Fedorov, Predrag Dašić, Mike Portnoy,

The laser processing has the ability for effective machining of ceramic materials because of high energy beam acting on a very small area. The stress-strain state of surface layer of Si 3 N 4 ceramics in laser processing was investigated with the use of finite element method to compute the temperature and stress fields. The effect of heat flow on thermal stresses was discussed in terms of the results of the numerical experiment.

Tópico(s): Advanced machining processes and optimization

2015 - Trans Tech Publications | Applied Mechanics and Materials

Carta Acesso aberto Revisado por pares

Mike Strickland,

... paper by Bush et al.1Bush R.K. Portnoy J.M. Saxon A. Terr A.l. Wood ... paper by Bush et al.1Bush R.K. Portnoy J.M. Saxon A. Terr A.l. Wood ...

Tópico(s): Air Quality and Health Impacts

2006 - Elsevier BV | Journal of Allergy and Clinical Immunology

Carta Acesso aberto Revisado por pares

Bernhard T. Baune,

... 805.LinkGoogle Scholar7 West CG, Gildengorin G, Haegerstrom-Portnoy G, Schneck ME, Lott L, Brabyn JA. Is ... A, Shenhar-Tsarfaty S, Aizenstein O, Hallevi H, Mike A, Shopin L, Bornstein N, Bashat D and ... Aizenstein O, Soreq H, Katz N, Solomon Z, Mike A, Usher S, Hausdorff J, Auriel E, Shapira ...

Tópico(s): Blood Pressure and Hypertension Studies

2009 - Lippincott Williams & Wilkins | Stroke

Artigo Acesso aberto Revisado por pares

Brahmdeep S. Saini, Meng Yuan Zhu, Sharon Portnoy, Prashob Porayette, Jessie Mei Lim, Abing Duan, John G. Sled, Rachel M. Wald, Rory Windrim, Christopher K. Macgowan, John‏ Kingdom, Mike Seed,

To investigate the use of MRI to assess placental function in terms of placental-fetal oxygen (O2) transport in utero. Eight women with normal pregnancies were scanned using a 1.5 T Siemens MRI system. To measure placental-fetal O2 transport, blood flow (Q) and oxygen content (C) were measured in blood vessels supplying (uterine arteries and fetal descending aorta) and draining (uterine, ovarian and umbilical veins) the placenta. Phase contrast MRI was used to measure Q. Vascular blood T1 and T2 MRI ...

Tópico(s): Pregnancy and preeclampsia studies

2016 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

Meng Yuan Zhu, Sarah Keating, Natasha Milligan, Rory Windrim, Sharon Portnoy, John G. Sled, Christopher K. Macgowan, John‏ Kingdom, Mike Seed,

To compare fetal hemodynamic measurements by Doppler and MRI in IUGR fetuses versus non-IUGR fetuses. Fetal body and brain weight, blood flow and oxygen saturations were measured using our previously published MRI technique1. Fetal O2 delivery (DO2) and consumption (VO2) were calculated using an estimated [Hb]2. We obtained MCA PI, UA PI and cerebroplacental ratio (CPR). IUGR patients were identified based on clinical data. The sensitivity and specificity of MRI and Doppler markers in IUGR detection ...

Tópico(s): Pregnancy and preeclampsia studies

2015 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

Joyce Lim, Prakash Muthusami, Sujana Madathil, Meng Yuan Zhu, Brahmdeep S. Saini, Prashob Porayette, Vann Chau, Sharon Portnoy, Christopher K. Macgowan, John G. Sled, John‏ Kingdom, Mike Seed, Steven P. Miller,

To investigate the relationship between fetal hemodynamics and brain growth and maturation in congenital heart disease (CHD) fetuses using magnetic resonance imaging (MRI). Fetal and newborn brain MRI was performed at 37 ± 1 and 40 ± 1.5 weeks respectively on a 1.5 T scanner. Fetal hemodynamics were assessed using our previously published technique, consisting of blood flow measures and T2 based oximetry. We measured fetal combined ventricular output (CVO), umbilical vein (UV) flow, oxygen content (estimated ...

Tópico(s): Pregnancy and preeclampsia studies

2016 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

Fu‐Tsuen Lee, Liqun Sun, Joshua van Amerom, Sharon Portnoy, Davide Marini, Amandeep Saini, Natasha Milligan, Jessie Mei Lim, Brahmdeep S. Saini, Thiviya Selvanathan, Vanna Kazazian, Renée Sananes, Edgar Jaeggi, John‏ Kingdom, Christopher K. Macgowan, Linh Ly, Vann Chau, Steven P. Miller, Mike Seed,

Fetuses with cyanotic congenital heart disease (CHD) exhibit profound fetal circulatory disturbances that may affect early outcomes. This study sought to investigate the relationship between fetal hemodynamics and early survival and neurodevelopmental (ND) outcomes in patients with cyanotic CHD. In this longitudinal observational study, fetuses with cyanotic CHD underwent late gestational fetal cardiovascular magnetic resonance (CMR) to measure vessel blood flow and oxygen content. Superior vena cava ( ...

Tópico(s): Congenital heart defects research

2024 - Elsevier BV | Journal of the American College of Cardiology

Artigo Acesso aberto Revisado por pares

Mohammad A. Alsayegh, Hanan Alshamali, Mousa Khadada, A Ciccolini, Anne K. Ellis, Diana Quint, William Powley, Laurie Lee, Yahya Fiteih, Shairaz Baksh, Harissios Vliagoftis, Sebastien K. Gerega, Brad Millson, Katia Charland, Stéphane Barakat, Xichun Sun, Ricardo Jimenez, Susan Waserman, Mark J. Fitzgerald, Jacques Hébert, Josiane Cognet-Sicé, Kevin E. Renahan, Saiful Huq, Rishma Chooniedass, Scott Sawyer, Hans Pasterkamp, Allan B. Becker, Steven G. Smith, Shi‐Yuan Zhang, K. M. P. D. Jayasundara, Claire E. Tacon, Alexander Simidchiev, Gilbert Nadeau, Necdet B. Gunsoy, Hana Müllerová, Frank C. Albers, Young Woong Kim, Casey P. Shannon, Amrit Singh, Helen Neighbour, Mark Larché, Scott J. Tebbutt, Annika Klopp, Lorena Vehling, Allan B. Becker, Padmaja Subbarao, Piush J. Mandhane, Stuart E. Turvey, Malcolm R. Sears, Meghan B. Azad, Keely Loewen, Barret A. Monchka, Salaheddin M. Mahmud, Geert ‘t Jong, Cristina Longo, Gillian Bartlett, Francine M. Ducharme, Tibor Schuster, Brenda MacGibbon, Tracie A. Barnett, Michelle L. North, Jeff Brook, Elizabeth Lee, Vanessa Omana, Jenny Thiele, Lisa M. Steacy, Greg J. Evans, Miriam L. Diamond, Gordon Sussman, Yann Amistani, Kathy Abiteboul, Mark W. Tenn, Chenxi Yang, Christopher Carlsten, Edward M. Conway, Douglas P. Mack, Rofina Yasmin Othman, Colin Barber, Chrystyna Kalicinsky, Andrea E. Burke, Mary Messieh, Parameswaran Nair, Tae‐Wook Chun, Lindsay Douglas, Joel Liem, Lucy Duan, Charlotte Miller, Pascale Dupuis, Lori Connors, Michael Fein, Joseph Shuster, Hani Hadi, Brooke I. Polk, Nikita Raje, Roxane Labrosse, Philippe Bégin, Louis Paradis, Anne Des Roches, Jonathan Lacombe‐Barrios, Sanju Mishra, Gina Lacuesta, Meredith Chiasson, Babar Haroon, Kara Robertson, Thomas B. Issekutz, Desmond Leddin, Stephen Couban, Lori Connors, Adrienne M. Roos, Amin Kanani, Edmond S. Chan, R. Robert Schellenberg, Lana Rosenfield, Anna Cvetkovic, K. N. Woodward, Jaclyn Quirt, Wade Watson, Edson Castilho, Jennifer A. Sullivan, Beverley Temple, Donna Martin, Victoria E. Cook, C. A. Mills, Élodie Portales-Casamar, Lisa Fu, Alexander Ho, Jeffrey S. Zaltzman, Lucy Chen, Peter Vadas, Sofianne Gabrielli, Ann E. Clarke, Harley Eisman, Judy Morris, Lawrence Joseph, Sebastien LaVieille, Moshe Ben‐Shoshan, François Graham, Charles S. Barnes, Jay M. Portnoy, Vincent Stagg, Elinor Simons, Diana L. Lefebvre, David Dai, Piush J. Mandhane, Malcolm R. Sears, Herman Tam, F. Estelle R. Simons, Dhaifallah S Alotaibi, Bassel Dawod, Matthew Tunis, Jean S. Marshall, Marylin Desjardins, Marianne Béland, Duncan Lejtenyi, Jean-Phillipe Drolet, Martine Lemire, Christos Tsoukas, Francisco Noya, Reza Alizadehfar, Christine McCusker, Bruce Mazer, Danay Maestre‐Batlle, Evelyn Gunawan, Christopher F. Rider, Anette Kocbach Bølling, Olga M. Pena, Daniel Suez, Isaac Melamed, Iftikhar Hussain, Mark R. Stein, Sudhir Gupta, Kenneth Paris, Sandor Fritsch, Christelle Bourgeois, Heinz Leibl, Barbara McCoy, Martin Noël, Leman Yel, Ori Scott, Brenda Reid, Adelle Atkinson, Vy Hong-Diep Kim, Chaim M. Roifman, Eyal Grunebaum, Eiman Al‐Selahi, Fernando Alemán, Amber Oberle, Mike Trus, Gordon Sussman, Amin Kanani, Olivier Chambenoi, Sima Chiva-Razavi, Savannah Grodecki, Nikhil Joshi, Peter Menikefs, David Holt, Teresa Pun, Damian Tworek, Raphael Hanna, Delia Heroux, Elli Rosenberg, Leah T. Stiemsma, Stuart E. Turvey, Judah A. Denburg, Christopher P. Mill, Timothy Teoh, Preeti Zimmer, Vishal Avinashi, Mihaela Paina, Ahmed A. Darwish Hassan, John Paul Oliveria, Chris Olesovsky, Gail M. Gauvreau, Linda Pedder, Paul K. Keith, Greg Plunkett, Michelle L. Bolner, Persia Pourshahnazari, Donald Stark, Kateryna Vostretsova, Andrew A. Moses, A. Maurice Wakeman, Alexander Singer, Thomas Gerstner, Elissa M. Abrams, Sara F. Johnson, Roberta L. Woodgate,

Background: Multiple animal antigens, spores and pollens were collected and identified from the Kuwaiti atmosphere.The role for these antigens in mediating allergic rhinitis for Kuwaiti residents needs to be evaluated.Objective: To investigate the causes (both indoors and outdoors) of allergic rhinitis for Kuwaiti residents.Method: This is a retrospective study of all positive skin tests that we obtained in our Allergy clinic in Mubarak Alkabeer Hospital in Kuwait, during the period between May 2013 ...

Tópico(s): Immunodeficiency and Autoimmune Disorders

2017 - BioMed Central | Allergy Asthma and Clinical Immunology

Artigo Acesso aberto Revisado por pares

Anqi Duan, Meng Yuan Zhu, Sharon Portnoy, Natasha Milligan, Jessie Mei Lim, Johannes Keunen, Christopher K. Macgowan, John G. Sled, John‏ Kingdom, Mike Seed,

Fetal brain to liver weight ratio has been identified as a useful diagnostic tool of intrauterine growth restrictions (IUGR) in a study of stillborn babies and neonatal deaths [1]. We sought to investigate whether fetal brain to liver volume ratio (BLVR), measured by MRI, could be used as a potential indicator of IUGR in vivo in live fetuses. This study included 16 fetuses in the normal group and 15 fetuses in the IUGR group between 32 and 39 weeks gestation. Meeting ≥ 2 of the 4 criteria proposed by ...

Tópico(s): Fetal and Pediatric Neurological Disorders

2016 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Revisado por pares

Liqun Sun, Fu‐Tsuen Lee, Joshua F van Ameron, Sharon Portnoy, Jessie Mei Lim, Brahmdeep S. Saini, Edgar Jaeggi, John‏ Kingdom, Christopher K. Macgowan, Steven P. Miller, Mike Seed,

Introduction: Abnormal fetal growth and development are evident in patients with cyanotic congenital heart disease (cCHD). However, the relationship between growth and fetal oxygenation is unknown. We sought to investigate the relationship between fetal hemodynamics and fetal growth in cCHD using fetal cardiovascular Magnetic Resonance Imaging (MRI). Hypothesis: The impaired fetal oxygenation would be associated with diminished fetal brain and body growth in cCHD. Methods: We performed a prospective ...

Tópico(s): Cardiovascular Issues in Pregnancy

2021 - Lippincott Williams & Wilkins | Circulation

Artigo Acesso aberto Revisado por pares

Anqi Duan, Johannes Keunen, Sharon Portnoy, Meng Yuan Zhu, C. Anastasiadis, Greg Ryan, Prashob Porayette, Brahmdeep S. Saini, John G. Sled, Christopher K. Macgowan, Mike Seed,

The detection of fetal anemia by middle cerebral artery peak systolic velocity is less reliable with advancing gestational age (GA) and prior transfusion. We sought to investigate the feasibility and accuracy of a new MRI method for measuring fetal hematocrit (Hct) in vivo in anemic fetuses. We recruited 4 pregnant women suspected of carrying anemic fetuses between 19 and 38 weeks GA. Two fetuses had Rh alloimmunisation, one had alpha-thalassemia and two had twin anemia-polycythemia sequence. The ...

Tópico(s): Parvovirus B19 Infection Studies

2016 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Revisado por pares

Liqun Sun, Fu‐Tsuen Lee, Adrienn Szabo, Mika Saito, Nathaniel Barber, Joshua van Ameron, Sharon Portnoy, Davide Marini, Brahmdeep S. Saini, Diana Balmer‐Minnes, Vitor Guerra, Varsha Thakur, Christopher K. Macgowan, Steven P. Miller, Edgar Jaeggi, Mike Seed,

Introduction: The presence of a restrictive atrial septum in the setting of transposition of the great arteries (TGA) is associated with a high risk of hypoxic ischemic injury upon transition to postnatal circulation. Fetal cardiovascular magnetic resonance (CMR) measures of vessel flow and oxygen saturation provide a unique opportunity to study fetal TGA hemodynamics at baseline and during acute maternal hyperoxygenation. Methods: Thirty-one pregnant mothers with fetuses diagnosed with TGA and an ...

Tópico(s): Fetal and Pediatric Neurological Disorders

2023 - Lippincott Williams & Wilkins | Circulation

Editorial Acesso aberto Revisado por pares

Arturo Casadevall,

... Pontes David L. Popham Matteo Porotto Daniel A. Portnoy Christopher Power Rajendra Prasad Andrew Preston Jeffrey W. ...

Tópico(s): Information Retrieval and Data Mining

2021 - American Society for Microbiology | mBio

Artigo Acesso aberto Revisado por pares

Harold L. Drake,

... Pope Holly Popham Georgy Popov Rachel Poretsky Daniel Portnoy Robert Potter Vittal Prakash Mirja Puolakkainen Alexandra Purdy ...

Tópico(s): Islamic Finance and Banking Studies

2020 - American Society for Microbiology | Applied and Environmental Microbiology