Elaine S. Krause, E.F. Stumpfl, M.R. Littlewood, Colin Mcintyrg, Douglas Jay, Maureen Duffy, R.E. Benns, P.J.W. Henderson, Donald P. Mazzella, J. Vuillequez, David Stevenson, Saeed Feyz,
... A hammer without a handle? Interunion Banque Linguaphone Minilab Mitsui Trust Cessna/Citation Halifax ICI Dash 7 ...
1976 - Gale Group | The Economist
Global Pharma Health Fund (GPHF) Minilab™, a semi-quantitative thin-layer chromatography (TLC)-based commercially available test kit, is widely used in drug quality surveillance globally, but ... is unclear. We investigated the diagnostic accuracy of Minilab system for antimicrobials, using high-performance liquid chromatography (HPLC) as reference standard. Following the Minilab protocols and the Pharmacopoeia of the People's Republic of China protocols, Minilab-TLC and HPLC were used to test five ... prevalence of poor-quality antimicrobials determined, respectively, by Minilab TLC and HPLC was amoxicillin (0% versus 14. ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2017 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Albert Petersen, Nadja Held, Lutz Heide,
... Africa and Asia were each equipped with a Minilab of the Global Pharma Health Fund (GPHF, Frankfurt, ... medicine samples were tested locally according to the Minilab protocols. Medicines which failed Minilab testing were subjected to confirmatory analysis in a ... all antimalarials). Thin-layer chromatography according to the Minilab protocols was found to be specific and reproducible ... the stated API. Since only samples which failed Minilab testing were subjected to confirmatory testing using pharmacopeial ...
Tópico(s): Intellectual Property and Patents
2017 - Public Library of Science | PLoS ONE
Gesa Gnegel, Christine Häfele-Abah, Richard Neci, Markous Alladjaba, Micha Lächele, Neenodji Grace, Ndilta Djekadoum, Julien Basile Gounouman, Servilien Mpawenimana, Egide Muziganyi, Anastasie Mukamanzi, Jean Claude Zawadi, Tambo Ajong Cletus, Ndze Edward Ngah, Bishnu Chakraborty, Georges Mutombo, Sr Jane Frances Chioke, Esther Okpan, Juliet Ngene, Emmanuel Higenyi, Priscilla Agiro, Titus Uggi, Tumaini Petro Anderson, Pamella Ndakengurutse, Emmanuel Ndayikeza, Stephen Kigera, Mildred Wanyama, Frederick Sowah, Fredrick Kachiponde, Folita Malanda, Dina Pecke Julienne, Fidelis Nyaah, Manyi Pattinora Dohnji, Richard Neci, Gesa Gnegel, Christine Häfele-Abah, Lutz Heide,
... use of the Global Pharma Health Fund (GPHF) Minilab for medicine quality screening by 16 faith-based ... 919 medicine samples were screened using the GPHF Minilab, and samples showing serious quality deficiencies were subjected ... due to the limited sensitivity of the GPHF Minilab. The number of probably falsified products increased during ... alerts. Within this project, the costs for GPHF Minilab analysis resulted as 25.85 € per sample. Medicine quality screening with the GPHF Minilab is a cost-effective way to contribute to ...
Tópico(s): Food Safety and Hygiene
2022 - Nature Portfolio | Scientific Reports
... using the Global Pharma Health Fund e.V. Minilab® protocol. Random sampling of medicines from the two ... counterfeit producers may be adapting products to pass Minilab tests, the results are compared with those from ... February 2010). All samples were tested using the Minilab® protocol, which includes disintegration and active ingredient assays ... to 29% of the 2007 finding using the Minilab® protocol, 53% using Raman spectrometry, and 46% using ... to 54% of the 2007 finding using the Minilab® protocol, 72% using Raman spectrometry, and 90% using ...
Tópico(s): Diverse Scientific Research Studies
2010 - BioMed Central | Malaria Journal
JaCinta S. Batson, Daniel K. Bempong, Patrick Lukulay, Nicola Ranieri, R. Duane Satzger, Leigh Verbois,
... screening technologies—TruScan™ Portable Raman spectrometer and GPHF Minilab®. A total of 84 anti-malarial test samples ... 00 in detecting counterfeit/substandard products compared to Minilab (0.79) and TruScan (0.79). CD3+ had ... authentic products compared to the specificities reached by Minilab (0.99) and TruScan (1.00). High sensitivity ... 1.00) and specificity (0.99); and the Minilab provided sensitivity (1.00) and specificity (1.00). ... Using a combination of CD3+, with either the Minilab or TruScan, to screen for medicine quality will ...
Tópico(s): Identification and Quantification in Food
2016 - BioMed Central | Malaria Journal
Peter Risha, Zera Msuya, Malcolm Clark, Keith Johnson, Margareth Ndomondo-Sigonda, Thomas Layloff,
... Food and Drugs Authority piloted the use of Minilab® kits, a thin-layer-chromatographic based drug quality ... market. After 1 week training of inspectors on Minilab® screening techniques, they were stationed at key Ports- ... process. Over 1200 samples were tested using the Minilab® outside the central quality control laboratory (QCL), almost ... of substandard medicines into market. The use of Minilab® for quality screening was inexpensive and provided a ...
Tópico(s): Biosimilars and Bioanalytical Methods
2008 - Elsevier BV | Health Policy
... published in the Global Pharma Health Fund (GPHF) Minilab Manual and U.S. Food and Drug Administration ( ... screening methods for counterfeit pharmaceutical products in the Minilab Manual and FDA Compendium to HPTLC-densitometry using ... methods for pharmaceutical products not included in the Minilab Manual or FDA Compendium using the model process ... Supplemental FDA Compendium TLC screening methods; and modified Minilab methods with simplified detection based on heating of ...
Tópico(s): Chromatography in Natural Products
2019 - Taylor & Francis | Journal of Liquid Chromatography &Related Technologies
Kui-Xiang Ma, Tobias Ekblad, M. Klein Koerkamp, Henry Kelderman, Melchior van Wijlen, Ankur Duarah, Junqi Yue, Lifeng Zhang, Mark Vee-Meng Wong, Mong Hoo Lim,
... water has been developed and validated for the MiniLab™ system from Optiqua Technologies. This biosensor-based analytical ... known amounts of BPA and tested with the MiniLab™ system. The working range of the BPA inhibition ... effective system that can be field deployed, the MiniLab™ system enables target-specific assays currently only available ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2015 - Taylor & Francis | International Journal of Environmental & Analytical Chemistry
Benjamin J Visser, Janneke Meerveld-Gerrits, Daniëlle Kroon, Judith Mougoula, Rieke Vingerling, Emmanuel B. Bache, Jimmy Boersma, Michèle van Vugt, Selidji T Agnandji, Harparkash Kaur, Martin P. Grobusch,
... was conducted using the Global Pharma Health Fund Minilab® tests, following the Medicine Quality Assessment Reporting Guidelines. ... 84%). Two out of 432 samples failed the MiniLab® semi-quantitative TLC test, of which a suspected ... malarial drugs at a pharmacy. Using the GPHF Minilab®, the prevalence of poor-quality anti-malarial drugs ...
Tópico(s): Pharmaceutical Economics and Policy
2015 - BioMed Central | Malaria Journal
Kwabena F.M. Opuni, Henry Nettey, Marvin Adjei Larbi, Salome Naa Amerley Amartey, Gifty Akpene Nti, Abraham Dzidonu, Patrick Owusu-Danso, Nicholas Amoah Owusu, Alexander K. Nyarko,
... Ghana were analysed using three screening methods (GPHF Minilab, Colorimetry and Counterfeit Drug Indicator) and one confirmatory ... no active ingredient (0%), respectively. The sensitivity of Minilab, colorimetric, CoDI, and the combined screening methods at ... 83 ± 0.33, respectively. Also, the specificity of Minilab, colorimetric, CoDI, and the combined screening methods at ...
Tópico(s): Identification and Quantification in Food
2019 - BioMed Central | Malaria Journal
Yiru Gu, Bingsong Zeng, J. Sherma,
... published in the Global Pharma Health Fund (GPHF) Minilab Manual designed for identification of counterfeit and substandard ... which TLC screening methods are published for the Minilab, but HPTLC–densitometry procedures were developed for them ...
Tópico(s): Chromatography in Natural Products
2019 - University of Silesia in Katowice | Acta Chromatographica
Jacob Strock, Nguyễn Thị Tuyết, J. Sherma,
... thin-layer chromatography (TLC) Global Pharma Health Fund Minilab mobile kit protocols for detecting fake pharmaceutical products ... visual zone comparison that do not allow the Minilab TLC procedures to support regulatory compliance actions. These ...
Tópico(s): Computational Drug Discovery Methods
2015 - University of Silesia in Katowice | Acta Chromatographica
Cong Wang, Jing Wang, Chenyang Yu, Bingtian Wu, Wang Ya, Wenguang Li,
Abstract HAAKE MiniLab is an apparatus specially designed for compounding polymer material and on-line testing of rheological properties. For the ... the steady-state torque with rotation speed. Therefore, MiniLab would be a very useful tool in exploring ...
Tópico(s): Injection Molding Process and Properties
2013 - Elsevier BV | Polymer Testing
... of methods by Kenyon and Layloff and/or Minilab method manuals from Global Pharma Health Fund E. ... hydrochloride, for which there was no Compendium or Minilab method that could be transferred. These quantitative methods ... comparison that do not allow the Compendium and Minilab TLC procedures to support regulatory compliance actions. These ...
Tópico(s): Pesticide Residue Analysis and Safety
2013 - Taylor & Francis | Journal of Liquid Chromatography &Related Technologies
Simon Schäfermann, Cathrin Hauk, Emmanuel Wemakor, Richard Neci, Georges Mutombo, Edward Ngah Ndze, Tambo Ajong Cletus, Fidelis Nyaah, Manyi Pattinora, Dorothee Wistuba, Irina Helmle, Christine Häfele-Abah, Harald Gross, Lutz Heide,
... DR Congo with the Global Pharma Health Fund Minilab (thin-layer chromatography and disintegration testing). The three falsified medicines were readily detected in Minilab analysis. However, substandard samples were detected with low ...
Tópico(s): Intellectual Property and Patents
2020 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Serena Vickers, Matthew C. Bernier, Stephen C. Zambrzycki, Facundo M. Fernández, Paul N. Newton, Céline Caillet,
... Only six devices had been field-tested (GPHF-Minilab, CD3/CD3+, TruScan RM, lateral flow dipstick immunoassay, ... semi)-quantitatively required consumables and were destructive (GPHF-Minilab, PharmaChk, aPADs, lateral flow immunoassay dipsticks, paper-based ...
Tópico(s): Biosensors and Analytical Detection
2018 - BMJ | BMJ Global Health
Mirza Lalani, Harparkash Kaur, Nader Mohammed, Naiela Mailk, Albert van Wyk, Sakhi Jan, Rishtya Meena Kakar, Mohammed Khalid Mojadidi, Toby Leslie,
... screened using the Global Pharma Health Fund (GPHF) MiniLab® in Kabul with 33/126 (26%) samples failing the MiniLab® disintegration test. The quality of a subsample (N = ...
Tópico(s): Pharmaceutical Economics and Policy
2015 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Ifeyinwa Fadeyi, Mirza Lalani, Naiela Mailk, Albert van Wyk, Harparkash Kaur,
... was assessed using German Pharma Health Fund (GPHF) MiniLab® as the screening tool-two capsules of amoxicillin ( ... for co-trimoxazole and amoxicillin samples using the MiniLab® TLC tests. This highlights the need to invest ...
Tópico(s): Antibiotic Use and Resistance
2015 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Jacob Strock, Nguyễn Thị Tuyết, Joseph Sherma,
... transfer of TLC screening methods contained in the Minilab manual from Global Pharma Health Fund E.V. ...
Tópico(s): Plant-based Medicinal Research
2015 - Taylor & Francis | Journal of Liquid Chromatography &Related Technologies
Sam Douthwaite, Charlotte Walker, Elisabeth J Adams, Catherine Mak, Andres I. Vecino‐Ortiz, Nuria Martinez-Alier, Simon Goldenberg,
ABSTRACT The performance of the Enigma MiniLab assay for influenza A and B viruses and respiratory syncytial virus (RSV) was compared to a centralized laboratory respiratory virus panel. The ...
Tópico(s): Influenza Virus Research Studies
2015 - American Society for Microbiology | Journal of Clinical Microbiology
Nguyễn Thị Tuyết, Joseph Sherma,
... Compendium developed by Kenyon and Layloff and GPHF Minilab manuals for use in countries with limited resources. ... CAMAG Scanner 3. Attempts to transfer Compendium and Minilab TLC methods for amoxicillin according to the model ...
Tópico(s): Pharmacological Effects of Natural Compounds
2014 - Taylor & Francis | Journal of Liquid Chromatography &Related Technologies
Peter Risha, Zera Msuya, Margareth Ndomondo-Sigonda, Thomas Layloff,
... in poor resource settings. We have established routine Minilab test procedures to screen product quality and a ... were given to inspectors for quality screening using Minilab procedures. In round 1 of the proficiency test, ...
Tópico(s): Biosimilars and Bioanalytical Methods
2006 - Oxford University Press | Journal of AOAC International
... concepts by hands-on experimentation — the concept-centered minilab — and lists possible minilabs for use in introductory physics courses. We have used minilabs successfully at Rutgers for 15 years. They are ...
Tópico(s): Experimental and Theoretical Physics Studies
2000 - American Association of Physics Teachers | The Physics Teacher
Ochekpe Nelson A, Agbowuro Ayodeji A, Attah Saadatu E,
... were analysed using the World Health Organization (WHO) minilab basic testing procedures and the results alongside their ...
Tópico(s): Pharmaceutical Quality and Counterfeiting
2010 - | International Journal of Drug Development and Research
Bingsong Zeng, Yiru Gu, Kaitlin Nguyen, Joseph Sherma,
... chromatography (TLC) Global Pharma Health Fund E.V. Minilab Manual and U.S. Food and Drug Administration ( ... and pantoprazole that are not included in the Minilab Manual or FDA Compendium. The new methods involved ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2019 - Taylor & Francis | Journal of Liquid Chromatography &Related Technologies
Ellen M. Armour, Joseph Sherma,
... in the Global Pharma Health Fund E.V. Minilab manual for the identification of counterfeit drugs to ... drugs with TLC screening methods published in the Minilab manual and/or Compendium of Unofficial Methods for ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2017 - Taylor & Francis | Journal of Liquid Chromatography &Related Technologies
Sinmisola Oladeji, Valentyn Mohylyuk, D. Stephen Charnock‐Jones, Gavin P. Andrews,
... provides a tailored drug release profile. HME (HAAKE MiniLab) and FDM-3DP (MakerBot) were used to prepare ...
Tópico(s): Injection Molding Process and Properties
2022 - Elsevier BV | International Journal of Pharmaceutics
Cathrin Hauk, Mark Boss, Julia Gabel, Simon Schäfermann, Hendrik P. A. Lensch, Lutz Heide,
... procedures of the Global Pharma Health Fund (GPHF) Minilab was carried out, following international guidelines and assessing ...
Tópico(s): Biosimilars and Bioanalytical Methods
2022 - Nature Portfolio | Scientific Reports
Francis Kachidza Chiumia, Happy Magwaza Nyirongo, Elizabeth Kampira, Adamson S. Muula, Felix Khuluza,
... methods provided in the Global Pharma Health Fund minilab ® for the screening purposes. We conducted confirmatory test ...
Tópico(s): Antibiotic Use and Resistance
2022 - Public Library of Science | PLoS ONE