Produção Nacional
Revisado por pares
Ingrid Aguilar-Be, Renata da Silva Zardo, Edilma Paraguai de Souza, Gulnara Patrı́cia Borja-Cabrera, Miguel Rosado‐Vallado, Mirza Mut‐Martín, María del Rosario García‐Miss, M Palatnik, Eric Dumonteil,
The fucose-mannose ligand (FML) complex of Leishmania donovani is a promising vaccine candidate against murine and canine visceral leishmaniasis, and its main component is a 36-kDa nucleoside hydrolase (NH36). In this study, we tested the immune response and protection induced by the purified FML, the recombinant NH36 (rNH36), and NH36 DNA vaccines against the agents of visceral (L. chagasi) and cutaneous (L. mexicana) leishmaniasis in BALB/c mice. Mice developed weak humoral response to the vaccines ...
Tópico(s): T-cell and Retrovirus Studies
2005 - American Society for Microbiology | Infection and Immunity