Produção Nacional
Revisado por pares
Moacir Kaiser, Lauren Dockhorn Grünspan, Teresa Dalla Costa, Leandro Tasso,
A simple, accurate and precise high-performance liquid chromatographic method with fluorescence detection was developed and validated for the determination of gemifloxacin (GEM) in rat plasma using furosemide as internal standard (I.S.). Plasma samples were pretreated by direct deproteinization and all samples and standard solutions were chromatographed at 45°C using triethylamine solution (0.5%, v/v, pH 3.0±0.1), methanol and acetonitrile (63:30:7, v/v/v) as the mobile phase. Chromatographic resolution ...
Tópico(s): Pneumonia and Respiratory Infections
2011 - Elsevier BV | Journal of Chromatography B
Produção Nacional
Revisado por pares
Liberato Brum, Manoela Guerra Leal, Flávia De Toni Uchôa, Moacir Kaiser, Sı́lvia Stanisçuaski Guterres, Teresa Dalla Costa,
Tópico(s): Analytical Methods in Pharmaceuticals
2011 - Springer Science+Business Media | Chromatographia
Produção Nacional
Revisado por pares
Moacir Fernandes de Godoy, Hanna Rafaela Ferreira Dalla Pria, Hanna Rafaela Ferreira Dalla Pria,
INTRODUÇÃO: Várias escolas de Medicina do País criaram disciplinas para o ensino de Ética Médica, mas o impacto dessa intervenção não tem sido claramente questionado. OBJETIVO: Mensurar o conhecimento referente ao tema Ética Médica adquirido pelos alunos do curso de Medicina da Faculdade de Medicina de São José do Rio Preto (Famerp). MÉTODOS: Trata-se de estudo transversal descritivo. Os graduandos do ano letivo de 2012 responderam a um questionário autoaplicável com 12 questões objetivas, com três ...
Tópico(s): Innovations in Medical Education
2014 - Associção Brasileira de Educação Médica | Revista Brasileira de Educação Médica
Produção Nacional
Revisado por pares
A.E.D. Vieira, G.L. Araújo, Carolina Galassi, Rodrigo Freitas Rodrigues, G.D. Cassalli, Moacir Kaiser, Teresa Dalla Costa, Heloísa Beraldo, Carlos Alberto Tagliati,
Benzaldehyde semicarbazone (BS) has presented positive results in several pharmacological models, including anticonvulsivant and anti-inflammatory models. The present study evaluated the preclinical toxicity (acute and subchronic), as well as the toxicokinetic and gastroprotective effects of BS against ethanol lesions. Oral doses of 300 and 2000 mg/kg were used in the preclinical acute toxicity study; 100, 200, and 300 mg/kg were used in both the subchronic toxicity evaluation and the gastric study; ...
Tópico(s): Pharmacogenetics and Drug Metabolism
2013 - Elsevier BV | Food and Chemical Toxicology
Produção Nacional
Revisado por pares
Moacir Kaiser, Francine Johansson Azeredo, Flávia De Toni Uchôa, Heloísa Beraldo, Teresa Dalla Costa,
The study aimed to investigate the pharmacokinetics and tissue distribution of the benzaldehyde semicarbazone (BS) a potential antiepileptic drug, administered as a free drug or complexed β-cyclodextrin (BS/β-CD). Free BS and BS/β-CD were administered to male Wistar rats as a 10 mg/kg intravenous bolus dose. For the oral route, 50 mg/kg and 100 mg/kg doses of the free drug and 50 mg/kg of the complex were administrated and plasma concentrations were determinated by a validated HPLC-UV method. Individual ...
Tópico(s): Drug Solubulity and Delivery Systems
2010 - Elsevier BV | European Journal of Pharmaceutical Sciences
The analysis of the short stories “O Cobrador” and “Onze deMaio” (O Cobrador, 1979), of Rubem Fonseca (1925 -), it demonstrates that the postmodernism became an intellectual movement questioner of the social differences. Fonseca's work approaches, with clarity, the disorder, the disaggregation, the absence of defined values, the social crisis and the physical and mental violence, found in the Brazilian cities. The incorporationof the means of mass communication in the narrative is good to evidence the difference ...
Tópico(s): Linguistics and Education Research
2005 - Costa Rica Institute of Technology | Trama Revista de Ciencias Sociales y Humanidades
Produção Nacional
Jéssica de Almeida, Moacir Dalla Palma,
O presente artigo propõe analisar como se dá a representação da violência social nos contos “Onze de Maio” e “Anjos das Marquises” de Rubem Fonseca, o qual é um dos maiores escritores brasileiros a versar sobre violência e vozes marginalizadas. Para tal, buscou-se analisar a relação entre violência e literatura, além de discutir questões referentes às representações sociais acerca de indivíduos marginalizados no Brasil. Ao se observar a violência tão presente na sociedade brasileira, torna-se importante ...
Tópico(s): Youth, Drugs, and Violence
2023 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Letras
Produção Nacional
Revisado por pares
Felipe K. Hurtado, Moacir Kaiser, Leandro Tasso, Teresa Dalla Costa,
A fast, simple, and sensitive reversed-phase high-performance liquid chromatography (RP-HPLC) method has been developed and fully validated for the determination of moxifloxacin (MXF) in rat plasma. MXF and gatifloxacin (internal standard, I.S.) were extracted from plasma by single-step protein precipitation with acidified acetonitrile. Chromatographic separation was accomplished in less than 8 min on an Atlantis ® T3 column with 0.4% aqueous triethylamine–methanol–acetonitrile (60:35:5, v / v / v ) solution ...
Tópico(s): Pneumonia and Respiratory Infections
2015 - University of Silesia in Katowice | Acta Chromatographica
Produção Nacional
Revisado por pares
Gustavo C. Ferreira, Carolina Maso Viegas, Patrícia Fernanda Schuck, Anelise Miotti Tonin, César Augusto João Ribeiro, Daniella de Moura Coelho, Teresa Dalla Costa, Alexandra Latini, Ângela Terezinha de Souza Wyse, Clóvis Milton Duval Wannmacher, Carmen Regla Vargas, Moaçir Wajner,
Tópico(s): Metabolomics and Mass Spectrometry Studies
2005 - Springer Science+Business Media | Neurochemical Research
Produção Nacional
Revisado por pares
Lauren Dockhorn Grünspan, Moacir Kaiser, Felipe K. Hurtado, Teresa Dalla Costa, Leandro Tasso,
Tópico(s): Analytical Methods in Pharmaceuticals
2012 - Springer Science+Business Media | Chromatographia
Produção Nacional
Revisado por pares
Camila Pires, Moacir Kaiser, Lauren Dockhorn Grünspan, Fabiano Barreto, Adrine Maria Innocente, Simone Cristina Baggio Gnoatto, João Víctor Laureano, Bibiana Verlindo de Araújo, Teresa Dalla Costa, Leandro Tasso,
An accurate and reliable LC—MS/MS assay was firstly developed and validated for quantitative determination of a new antimalarial prototype drug, 3β-hydroxyurs-12-en-28-oic acid (LAFIS 01), in rat plasma. Dexamethasone was employed as internal standard. Simple protein precipitation by acetonitrile for the sample preparation was used. Effective separation was achieved with Phenomenex Luna C 18 (50 × 2 mm, 5 μm) column. The mobile phase consisted of (A) water and (B) acetonitrile, both containing 0.1% acetic ...
Tópico(s): Hormonal and reproductive studies
2016 - University of Silesia in Katowice | Acta Chromatographica
R. M. Bateman, Michael D. Sharpe, Justin E. Jagger, Chiara Ellis, Jordi Solé‐Violán, M. López Rodríguez, Estefanía Herrera‐Ramos, JA Ruiz-Hernández, Luis Borderías, Juan Pablo Horcajada, N. González-Quevedo, Olga Rajas, Ma Luisa Briones, Felipe Rodrı́guez de Castro, Claudio Gallego, Figen Esen, Günseli Orhun, Perihan Ergin Özcan, Evren Şentürk, Canan Uğur Yılmaz, Nurcan Orhan, Nadir Arıcan, M. Kaya, Melike Küçükerden, Murat Giriş, Uğur Akcan, Sema Bilgiç Gazioğlu, Eray Tüzün, Reut Riff, Oshri Naamani, Amos Douvdevani, Ryosuke Takegawa, Hisao Yoshida, Tomoya Hirose, Naoki Yamamoto, Hideharu Hagiya, Masahiro Ojima, Yukihiro Akeda, Osamu Tasaki, Kazunori Tomono, Takeshi Shimazu, Satoshi Ono, Toshio Kubo, S Suda, Takuya Ueno, T. Ikeda, Tomoya Hirose, Hiroshi Ogura, Hiroki Takahashi, Masahiro Ojima, J. Kang, Youhei Nakamura, Takashi Kojima, Takeshi Shimazu, T. Ikeda, S Suda, Yoshito Izutani, Takuya Ueno, Satoshi Ono, Tadatsugu Taniguchi, M. O, C. Dinter, J. Lotz, Beth Eilers, C. Wissmann, Rex S. Lott, Marc Meili, Philipp Schüetz, Hassan Hawa, Moh’d A. Sharshir, M. Aburageila, Nawal Salahuddin, Vasiliki Chantziara, Sophia Georgiou, Angeliki M. Tsimogianni, Panagiotis Alexandropoulos, A. Vassi, F. Lagiou, M. Valta, Georgia Micha, E. Chinou, G. Michaloudis, A. Kodaira, T. Ikeda, Satoshi Ono, Takuya Ueno, S Suda, Yoshito Izutani, Hitoshi Imaizumi, María Victoria de la Torre-Prados, A García-de la Torre, Alfredo Enguix-Armada, A Puerto-Morlán, V. Perez-Valero, Ángel García-Alcántara, N. Bolton, J. Dudziak, Samantha Bonney, Ascanio Tridente, Patrick Née, Gerry A. F. Nicolaes, Maryse A. Wiewel, MJ Schultz, K. Wildhagen, Janneke Horn, Roy Schrijver, Tom van der Poll, Chris Reutelingsperger, Suresh Pillai, G. Davies, Graham Mills, R. Aubrey, K. Morris, P. Williams, P. Evans, Étienne Gayat, Julian P. Struck, Alain Cariou, Nicolas Deye, Bertrand Guidet, S. Jabert, Jean‐Marie Launay, M Legrand, Marc Léone, Matthieu Resche‐Rigon, Éric Vicaut, Antoine Vieillard‐Baron, Amel Mebazâa, R. Arnold, Müge Capan, Adam Linder, Per Åkesson, M. Popescu, Dana Tomescu, Charles L. Sprung, Ricardo Morales, G Munteanu, Efrat Orenbuch‐Harroch, Phillip D. Levin, Harvey L. Kasdan, Austin Reiter, T. Volker, Y. Himmel, Yves Cohen, Julien Meissonnier, Louis Girard, Fabien Rebeaud, I. F. Herrmann, Benjamin Delwarde, Estelle Peronnet, Enrico Cerrato, Fabienne Venet, Alain Lepape, Thomas Rimmelé, Guillaume Monneret, Julien Textoris, Beloborodova Nv, V. Moroz, A. А. Osipov, A. Yu. Bedova, Y. Sarshor, Alisa Pautova, A. E. Sergeev, Ekaterina Chernevskaya, Jonas Odermatt, Rebekka Bolliger, Lara Hersberger, M. Ottiger, Mirjam Christ‐Crain, B. Mueller, Philipp Schüetz, Narendra Kumar Sharma, A. K. Tashima, Milena Karina Coló Brunialti, Flávia Ribeiro Machado, M. Assuncao, Otelo Rigato, Reinaldo Salomão, Sara Cajander, Gail E. Rasmussen, Elisabet Tina, Bo Söderquist, Jeremy Kallman, Kristoffer Strålin, A. L. Lange, Jonas Sundén‐Cullberg, Anders Magnuson, Olof Hultgren, G. Davies, Suresh Pillai, Graham Mills, R. Aubrey, K. Morris, P. Williams, P. Evans, Suresh Pillai, G. Davies, Graham Mills, R. Aubrey, K. Morris, P. Williams, P. Evans, Suresh Pillai, G. Davies, Graham Mills, R. Aubrey, K. Morris, Paul Williams, P. Evans, P. Van der Geest, Mostafa Mohseni, Jo Linssen, Rogier de Jonge, Servet Duran, Johan Groeneveld, R. Miller, Bert K. Lopansri, Leo McHugh, A. Seldon, J. P. Burke, J. Johnston, Rosie Reece-Anthony, A. Bond, A. Molokhia, Christopher McGrath, E. Nsutebu, Peter Bank Pedersen, Daniel Pilsgaard Henriksen, Søren Mikkelsen, Annmarie Touborg Lassen, R.C. Tincu, Cristian Cobilinschi, Dana Tomescu, Z. Ghiorghiu, Radu Alexandru Macovei, Maryse A. Wiewel, Matthew B.A. Harmon, Lonneke A. van Vught, Brendon P. Scicluna, Arie J. Hoogendijk, Janneke Horn, A. H. Zwinderman, Olaf L. Cremer, Marc J. M. Bonten, MJ Schultz, Tom van der Poll, N. P. Juffermans, W. Joost Wiersinga, Gülay Eren, Y. Tekdos, Mustafa Hakan Dogan, Özlem Acicbe, Ergün Barış Kaya, Oya Hergünsel, Sami Alsolamy, Ghassan Al Ghamdi, Lolowa Alswaidan, Saleh Alharbi, F. Alenezi, Yaseen M. Arabi, J. D. Heaton, Adam Boyce, Lea Nolan, J. Johnston, A. Dukoff-Gordon, A. Dean, A. Molokhia, T. Mann Ben Yehudah, C. Fleischmann, Daniel Thomas-Rüddel, C. Haas, U. Dennler, Konrad Reinhart, Onnicha Suntornlohanakul, Bodin Khwannimit, F. Breckenridge, Alex Puxty, Petr Szturz, P. Folwarzcny, Jan Švancara, Roman Kula, P. Sevcik, Luca Caneva, Alberto Casazza, E. Bellazzi, Serena Marra, Laura Pagani, M. Lo Vetere, R. Vanzino, D. Ciprandi, R. Preda, R. Boschi, L Carnevale, Victor Lopez, M. Aguilar Arzapalo, L. Barradas,
P001 - Sepsis impairs the capillary response within hypoxic capillaries and decreases erythrocyte oxygen-dependent ATP efflux R. M. Bateman, M. D. Sharpe, J. E. Jagger, C. G. Ellis P002 - Lower serum immunoglobulin G2 level does not predispose to severe flu. J. Solé-Violán, M. López-Rodríguez, E. Herrera-Ramos, J. Ruíz-Hernández, L. Borderías, J. Horcajada, N. González-Quevedo, O. Rajas, M. Briones, F. Rodríguez de Castro, C. Rodríguez Gallego P003 - Brain protective effects of intravenous immunoglobulin ...
BioMed Central
Produção Nacional
Revisado por pares
Moacir Kaiser, Francine Johansson Azeredo, Heloísa Beraldo, Teresa Dalla Costa,
Abstract A simple, rapid, and sensitive high performance liquid chromatographic method using UV detection (HPLC-UV) for the determination of benzaldehyde semicarbazone (BS) in rat plasma was developed and validated using sodium diclofenac as an internal standard (IS). Analyses were performed on an HPLC system using a C18 column and isocratic elution with mobile phase composed of water-methanol-acetonitrile (65:30:5, v/v/v) (pH 9.0), at a flow rate of 1.1 mL/min. The eluate was monitored using a UV detector ...
Tópico(s): Pharmacological Effects of Natural Compounds
2010 - Taylor & Francis | Journal of Liquid Chromatography &Related Technologies
Author et al, R. M. Bateman, Michael D. Sharpe, Justin E. Jagger, Chiara Ellis, Jordi Solé‐Violán, M. López Rodríguez, Estefanía Herrera‐Ramos, JA Ruiz-Hernández, Luis Borderías, Juan Pablo Horcajada, N. González-Quevedo, Olga Rajas, Ma Luisa Briones, Felipe Rodrı́guez de Castro, Claudio Gallego, Figen Esen, Günseli Orhun, Perihan Ergin Özcan, Evren Şentürk, Canan Uğur Yılmaz, Nurcan Orhan, Nadir Arıcan, M. Kaya, Melike Küçükerden, Murat Giriş, Uğur Akcan, Sema Bilgiç Gazioğlu, Erdem Tüzün, Reut Riff, Oshri Naamani, Amos Douvdevani, Ryosuke Takegawa, Hisao Yoshida, Tomoya Hirose, Naoki Yamamoto, Hideharu Hagiya, Masahiro Ojima, Yukihiro Akeda, Osamu Tasaki, Kazunori Tomono, Takeshi Shimazu, Satoshi Ono, Toshihide Kubo, S Suda, Takuya Ueno, T. Ikeda, Tomoya Hirose, Hiroshi Ogura, Hiroki Takahashi, Masahiro Ojima, J. Kang, Youhei Nakamura, Takashi Kojima, Takeshi Shimazu, Toshiaki Ikeda, S Suda, Yoshito Izutani, Takuya Ueno, Satoshi Ono, Tadatsugu Taniguchi, M. O, C. Dinter, Jan Lotz, Beth Eilers, C. Wissmann, Rex S. Lott, Marc Meili, Philipp Schüetz, Hassan Hawa, Moh’d A. Sharshir, M. Aburageila, Nawal Salahuddin, Vasiliki Chantziara, Sophia Georgiou, Angeliki M. Tsimogianni, Panagiotis Alexandropoulos, Avgi Vassi, F. Lagiou, M. Valta, Georgia Micha, E. Chinou, G. Michaloudis, A. Kodaira, Toshiaki Ikeda, Satoshi Ono, Takuya Ueno, S Suda, Yoshito Izutani, Hitoshi Imaizumi, María Victoria de la Torre-Prados, A García-de la Torre, Alfredo Enguix-Armada, A Puerto-Morlán, V. Perez-Valero, Ángel García-Alcántara, N. Bolton, J. Dudziak, Samantha Bonney, Ascanio Tridente, Patrick Née, Gerry A. F. Nicolaes, Maryse A. Wiewel, MJ Schultz, K. Wildhagen, Janneke Horn, Roy Schrijver, Tom van der Poll, Chris Reutelingsperger, Suresh Pillai, G. Davies, Graham Mills, R. Aubrey, K. Morris, Paul Williams, P. Evans, Étienne Gayat, Julian P. Struck, Alain Cariou, Nicolas Deye, Bertrand Guidet, S. Jabert, Jean‐Marie Launay, M Legrand, Marc Léone, Matthieu Resche‐Rigon, Éric Vicaut, Antoine Vieillard‐Baron, Amel Mebazâa, R. Arnold, Müge Capan, Adam Linder, Per Åkesson, M. Popescu, Dana Tomescu, Charles L. Sprung, Ricardo Morales, G Munteanu, Efrat Orenbuch‐Harroch, Phillip D. Levin, Harvey L. Kasdan, Austin Reiter, T. Volker, Y. Himmel, Yves Cohen, Julien Meissonnier, Louis Girard, Fabien Rebeaud, I. F. Herrmann, Benjamin Delwarde, Estelle Peronnet, Enrico Cerrato, Fabienne Venet, Alain Lepape, Thomas Rimmelé, Guillaume Monneret, Julien Textoris, Beloborodova Nv, V. Moroz, A. А. Osipov, A. Yu. Bedova, Y. Sarshor, Alisa Pautova, A. E. Sergeev, Ekaterina Chernevskaya, Jonas Odermatt, Rebekka Bolliger, Lara Hersberger, M. Ottiger, Mirjam Christ‐Crain, B. Mueller, Philipp Schüetz, Narendra Kumar Sharma, A. K. Tashima, Milena Karina Coló Brunialti, FR Machado, M. Assuncao, Otelo Rigato, Reinaldo Salomão, Sara Cajander, Gail E. Rasmussen, Elisabet Tina, Bo Söderquist, JK Källman, Kristoffer Strålin, A. L. Lange, Jonas Sundén‐Cullberg, Anders Magnuson, Olof Hultgren, G. Davies, Suresh Pillai, Graham Mills, R. Aubrey, K. Morris, Paul Williams, P. Evans, Suresh Pillai, G. Davies, Graham Mills, R. Aubrey, K. Morris, Paul Williams, P. Evans, Suresh Pillai, G. Davies, Graham Mills, R. Aubrey, K. Morris, Paul Williams, P. Evans, P. Van der Geest, Mostafa Mohseni, Jo Linssen, Rogier de Jonge, Servet Duran, Johan Groeneveld, R. Miller, Bert K. Lopansri, Leo McHugh, A. Seldon, J. P. Burke, J. Johnston, Rosie Reece-Anthony, A. Bond, A. Molokhia, Christopher McGrath, Emmanuel Nsutebu, Peter Bank Pedersen, Daniel Pilsgaard Henriksen, Søren Mikkelsen, Annmarie Touborg Lassen, R.C. Tincu, Cristian Cobilinschi, D. Tomescu, Z. Ghiorghiu, Radu Alexandru Macovei, Maryse A. Wiewel, Matthew B.A. Harmon, Lonneke A. van Vught, Brendon P. Scicluna, Arie J. Hoogendijk, Janneke Horn, A. H. Zwinderman, Olaf L. Cremer, Marc J. M. Bonten, MJ Schultz, Tom van der Poll, N. P. Juffermans, W. Joost Wiersinga, Gülay Eren, Y. Tekdos, Mustafa Hakan Dogan, Özlem Acicbe, Ergün Barış Kaya, Oya Hergünsel, Sami Alsolamy, Ghassan Al Ghamdi, Lolowa Alswaidan, Shmeylan Alharbi, F. Alenezi, Yaseen M. Arabi, J. D. Heaton, Adam Boyce, Lea Nolan, J. Johnston, A. Dukoff-Gordon, A. Dean, A. Molokhia, T. Mann Ben Yehudah, Carolin Fleischmann-Struzek, Daniel Thomas-Rüddel, C. Haas, U. Dennler, Konrad Reinhart, Onnicha Suntornlohanakul, Bodin Khwannimit, F. Breckenridge, Alex Puxty, Petr Szturz, P. Folwarzcny, Jan Švancara, Roman Kula, Pavel Ševčík, Luca Caneva, Alberto Casazza, E. Bellazzi, Serena Marra, Laura Pagani, M. Lo Vetere, R. Vanzino, D. Ciprandi, R. Preda, R. Boschi, L Carnevale, Victor Lopez, M. Aguilar Arzapalo,
[This corrects the article DOI: 10.1186/s13054-016-1208-6.].
BioMed Central