Jeffrey G. Shaffer, Frances J. Mather, Mamadou Wélé, Jian Li, Cheick Oumar Tangara, Yaya Kassogué, Sudesh Srivastav, Oumar Thiero, Mahamadou Diakité, Modibo Sangaré, Djénéba Dabitao, Mahamoudou Touré, Abdoulaye Djimdé, Sékou F. Traorè, Brehima Diakité, Mamadou B. Coulibaly, Yaozhong Liu, Michelle Lacey, John J. Lefante, Ousmane Koïta, John S. Schieffelin, Donald J. Krogstad, Seydou Doumbia,
Bioinformatics and data science research has boundless potential across Africa due to its high levels of genetic diversity and disproportionate burden of infectious diseases, including malaria, tuberculosis, HIV/AIDS, Ebola virus disease, and Lassa fever. This work lays out an incremental training approach for engaging underserved populations in bioinformatics and data science research at the University of Sciences, Techniques and Technologies of Bamako, Mali (USTTB). Two informatics training programs ...
Tópico(s): Biomedical and Engineering Education
2019 - Frontiers Media | Frontiers in Genetics
Tanya Guenther, Salim Sadruddin, Tiyese Chimuna, Bias Sichamba, Kojo Yeboah‐Antwi, Bamody Diakite, Modibo Bamadio, Eric Swedberg, David Marsh,
Health planners commonly use geographic proximity to define access to health services. However, effective access to case management requires reliable access to a trained, supplied provider. We defined effective access as the proportion of the study population with geographic access, corrected for other barriers, staffing patterns, and medicine availability. We measured effective access through a cross-sectional survey of 32 health facilities in Malawi, Mali, and Zambia and modeled the potential ...
Tópico(s): Child Nutrition and Water Access
2012 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Stéphane Ranque, Innocent Safeukui, Belco Poudiougou, Abdoulaye Traoré, Modibo Keita, Diamori Traoré, Mahamadou Diakité, Mahamadou B. Cissé, Marouf M. Keita, Ogobara K. Doumbo, Alain Dessein,
The predominant manifestations of severe malaria in African children are cerebral malaria (CM) and severe malarial anemia (SMA). As a first step toward a family-based approach to identify the environmental and genetic pathways that contribute to severe malaria, we tested whether it aggregates within families.Family history of severe malaria was explored during face-to-face interviews with parents. Logistic regression was used to determine whether CM and SMA aggregate within individuals and within ...
Tópico(s): Mosquito-borne diseases and control
2005 - Oxford University Press | The Journal of Infectious Diseases
T. Sidibé, H Sangho, Seydou Doumbia, M. Sylla, Modibo Keita, Haoua Dembélé Keïta, Bangaly Diakité, Abdelaye Keita, Ghislain Franck Houndjahoue,
Tópico(s): Global Health and Epidemiology
2006 - Elsevier BV | Journal de Pédiatrie et de Puériculture
Modibo Sangaré, Hamza B. Toure, Amadou Abdourhamane Touré, Adama Karembe, Housseini Dolo, Yaya Ibrahim Coulibaly, Modibo Kouyate, Kadiatou Traoré, Seidina A. S. Diakité, Souleymane Coulibaly, Arouna Togora, Cheick O. Guinto, Gordon A. Awandare, Seydou Doumbia, Mahamadou Diakité, Daniel H. Geschwind,
Early screening is crucial for early autism spectrum disorders (ASD) diagnosis and intervention. ASD screening tools have mostly been constructed based on the Western cultural context. We hypothesized that their use in Mali may require a prior validation.To validate the modified checklist for autism in toddlers-Revised (M-CHAT-R) and the social communication questionnaire (SCQ) in the Malian sociocultural context for ASD screening.We administered M-CHAT-R and SCQ in 947 toddlers aged 16-30 months old ...
Tópico(s): Child Development and Digital Technology
2019 - Elsevier BV | eNeurologicalSci
Innocent Safeukui-Noubissi, Stéphane Ranque, Belco Poudiougou, Modibo Keita, Abdoulaye Traoré, Diamori Traoré, Mahamadou Diakité, Mahamadou B. Cissé, Marouf M. Keita, Alain Dessein, Ogobara K. Doumbo,
The aim of this case-control study was to identify epidemiological risk factors for severe malaria among children living in Bamako, a malaria-endemic area. For this, 260 healthy community controls were matched to 130 patients with severe malaria. Conditional multiple logistic regression analysis indicated that all examined independent factors associated with severe malaria are directly related to characteristics of the child's mother, with the exception of the child's own yellow fever vaccination ...
Tópico(s): Global Maternal and Child Health
2004 - Elsevier BV | Microbes and Infection
Liv Elin Torheim, Ingrid Barikmo, Anne Hatløy, M Diakité, Kari Solvoll, Modibo M Diarra, Arne Oshaug,
The purpose of this study was to validate a quantitative food-frequency questionnaire (QFFQ) created for assessing the usual intake of foods and nutrients in the prevailing season in Western Mali.Intake of foods and nutrients over the week preceding the interview was measured with a 69-item QFFQ. Intakes were compared with intakes as measured with 2-day combined weighed and recalled diet records.A rural village in Western Mali, West Africa.Twenty-seven men and 48 women (15-59 years of age) representing ...
Tópico(s): Child Nutrition and Water Access
2001 - Cambridge University Press | Public Health Nutrition
A Togo, Abdoulaye Traoré, L Kanté, Y. Coulibaly, Djibo Diango, Modibo Keita, S. Diallo, Dembele B.T., I. Diakité, Noor Diani, B Samaké, Traore B.A., Gayo Diallo,
Nosocomial infections (NI) or hospital-acquired diseases are indicators of the quality of care. This study conducted in Mali aimed to determine the frequency of nosocomial infections, to recognize the risk factors, to identify the pathogens and their sensitivity to antibiotics and to determine the additional cost of care. The study lasted 6 months from January to June 2007, and the diagnosis of nosocomial infections was based on criteria from the USA C.D.C (Center for Disease Control). We identified ...
Tópico(s): Surgical site infection prevention
2010 - Bentham Science Publishers | The Open Biology Journal
Stéphane Ranque, Belco Poudiougou, Abdoulaye Traoré, Modibo Keita, Aboubacar Alassane Oumar, Innocent Safeukui, Sandrine Marquet, Sandrine Cabantous, Mahamadou Diakité, Daouda Mintha, Mahamadou B. Cissé, Marouf M. Keita, Alain J. Dessein, Ogobara K. Doumbo,
Background: The population exposed to malaria within African cities has steadily increased. However, comprehensive data on life-threatening malaria features and risk factors in children from urban areas with seasonal malaria transmission, such as in Bamako (Mali), are lacking. Methods: Children admitted to the Gabriel Touré Hospital in Bamako with severe malarial anemia (SMA) and/or cerebral malaria (CM) were prospectively included in the study. Indicators of either SMA or CM were analyzed using logistic ...
Tópico(s): Parasites and Host Interactions
2008 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
Seidina A. S. Diakité, Karim Traoré, Ibrahim Sanogo, Taane G. Clark, Susana Campino, Modibo Sangaré, Djénéba Dabitao, Antoine Dara, Drissa Konaté, Fousseyni Doucouré, Amadou Cissé, Bourama Keïta, Mory Doumbouya, Merepen A. Guindo, Mahamoudou Touré, Nafomon Sogoba, Seydou Doumbia, Gordon A. Awandare, Mahamadou Diakité,
Drug resistance is one of the greatest challenges of malaria control programme in Mali. Recent advances in next-generation sequencing (NGS) technologies provide new and effective ways of tracking drug-resistant malaria parasites in Africa. The diversity and the prevalence of Plasmodium falciparum drug-resistance molecular markers were assessed in Dangassa and Nioro-du-Sahel in Mali, two sites with distinct malaria transmission patterns. Dangassa has an intense seasonal malaria transmission, whereas ...
Tópico(s): Hepatitis C virus research
2019 - BioMed Central | Malaria Journal
Mariam Sylla, Fatoumata Dicko-Traoré, A Doumbia, Aminata Coulibaly, Abdoul Aziz Diakité, Modibo Sangaré, Pierre Togo, Fousseyni Traoré, Amadou Touré, D Konaté, Karamoko Sacko, Belco Maïga, Fatoumata Léonie Diakité, Lala N’Drainy Sidibé, Mohamed Cissé, Adama Dembélé, Hawa Diall, Oumar Coulibaly, Ibrahim Hamadou, Leyla Maïga, Issiaka Koné, B Togo, Toumani Sidibé,
Introduction: Acute post-infectious glomerulonephritis (APIGN) can be serious due to its complications that still occur in our countries. In this work, we aimed to study the epidemiological, clinical, biological and evolutionary aspects of APIGN. Patients and methods: We conducted a retrospective, descriptive study from January 1st, 2015 to December 31st, 2017 in the pediatric ward of the Gabriel Touré Teaching Hospital in Bamako. All children hospitalized for APIGN were included. Results: In two ...
Tópico(s): Renal Diseases and Glomerulopathies
2018 - Scientific Research Publishing | Open Journal of Pediatrics
Modibo Sangaré, B T Dembélé, Amadou Abdourhamane Touré, Seidina A. S. Diakité, Gordon A. Awandare, Modibo Kouyate, Seydou Doumbia, Mahamadou Diakité, Arouna Togora, Souleymane Coulibaly, Housseini Dolo,
Background: Autism spectrum disorders (ASD) are stigmatizing in Africa and traditional medical practitioners occupy the first line of diagnosis and treatment due to the cultural perception of ASD, and the scarcity of conventional health services in Mali. We aimed to assess the knowledge, attitudes, and practices (KAP) concerning autism among traditional medical practitioners in Bamako, Mali. Methods: We conducted a 6-week cross-sectional survey following a 1-day autism awareness seminary on September 9 th , 2017 ...
Tópico(s): Child Nutrition and Feeding Issues
2019 - Faculty of 1000 | AAS Open Research
Modibo Diakité, Brahima Sacko, Youssouf Gouro Diall, Amadou Séry, Mahamadou Konte, Sekouba Bengaly,
This study carried out between September and November 2023, in the Kangaba circle aimed to determine the prevalence of trypanosomiasis. Blood samples taken from 219 cattle comprising 142 females and 77 males examined for trypanosomes. Trypanosomes identified using the Buffy coat technique. This work made it possible to obtain a prevalence of 35.16% bovine trypanosoma. Statistical analysis revealed a statistically significant difference (p<0.05) between the prevalence rates observed in the different ...
Tópico(s): Trypanosoma species research and implications
2024 - | World Journal of Biology Pharmacy and Health Sciences
Modibo Diakité, Brahima Sacko, Catherine Traoré, Youssouf Gouro Diall, Amadou Séry, Maryam Diarra, Oumar Marico, F Sissoko, Sekouba Bengaly,
This study conducted between September and December 2022 in six municipalities in the Kita circle, with the aim of determining the prevalence of bovine trypanosomiasis. A sample of 450 cattle had their blood taken to test for trypanosomes. The cattle examined consisted of 239 females and 211 males. The different species of trypanosomes identified using the Buffy coat technique. This technique made it possible to obtain a prevalence of trypanosomes of 22.67%. This prevalence varied depending on sex ( ...
Tópico(s): Vector-Borne Animal Diseases
2024 - | World Journal of Biology Pharmacy and Health Sciences
Modibo Diakité, Brahima Sacko, Amadou Séry, Sekouba Bengaly,
This study, carried out between June 2019 and September 2020 in the localities of Kadiolo, Dioïla and Diéma, aimed to determine the prevalence of Babesia bovis and Babesia bigemina. It involved blood analysis of 648 cattle samples (327 females and 321 males) and tick collection for Babesia bigemina and Babesia bovis parasites and their vectors. During the dry season, 72 cattle tested positive for Babesia bovis out of a total of 324 examined, giving a prevalence rate of 22.22%. On the other hand, ...
Tópico(s): Agriculture and Rural Development Research
2023 - | World Journal of Biology Pharmacy and Health Sciences
Modibo Diakité, Brahima Sacko, Amadou Séry,
The study took place from June 2019 to September 2020 in the Sudanoguinean, Sudanian and Sahelian ecoclimatic zones of Mali. Its aim was to determine the prevalence of Babesia bovis and Babesia bigemina in each of these zones. A sample of 648 cattle, including 327 females and 321 males, examined for Babesia bigemina and Babesia bovis parasites and their vectors, using blood and tick sampling. Microscopic examination of the blood smears revealed the presence of the Babesia bovis parasite in 200 cattle ...
Tópico(s): Vector-borne infectious diseases
2023 - | World Journal of Biology Pharmacy and Health Sciences
Modibo Sangaré, Fluoribert Fousso, Amadou Abdourhamane Touré, Vignon Ghislan, Kadiatou Traoré, Souleymane Coulibaly, Boubacar Maïga, Modibo Kouyate, Oumar Sidibé, Seidina A. S. Diakité, Housseini Dolo, Siaka Yamoussa Coulibaly, Gordon A. Awandare, Souleymane Coulibaly, Arouna Togora, Seydou Doumbia, Yaya Ibrahim Coulibaly, Daniel H. Geschwind,
Background: The prevalence of autism spectrum disorders (ASD) is 1-2% worldwide, 1 in 68 in the U.S, and unknown in Africa. ASD is under-diagnosed in Mali due to stigma and the lack of appropriate human resources and infrastructure. Objective: To determine the ASD frequency and potential risk factors in Mali. Methods: We identified all the health facilities and community-based organizations involved in the ASD diagnosis and management in Bamako. We established an ASD research and awareness platform ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2019 - African Journals OnLine | African Journal of Neurological Sciences
Sory Ibrahima Diawara, Drissa Konaté, Kassoum Kayentao, Jules Mihigo, Jeffrey G. Shaffer, Modibo Sangaré, Protais Ndabamenye, Eric Swedberg, Lyndsey W. Garg, Nathalie Gamache, Bourama Keïta, Beh Kamaté, Philbert Ndaruhutse, Diakalia Koné, Vincent Sanogo, Moctar Tounkara, Mahamadou Diakité, Seydou Doumbia, Erin Eckert,
Seasonal malaria chemoprevention (SMC) has been widely expanded in Mali since its recommendation by the the World Health Organization in 2012. SMC guidelines currently target children between three months and five years of age. The SMC initiative has been largely successful. Children at least five years of age are not currently covered by current SMC guidelines but bear a considerable portion of the malaria burden. For this reason, this study sought to determine the feasibility and effectiveness ...
Tópico(s): Parasites and Host Interactions
2022 - Elsevier BV | Parasite Epidemiology and Control
Karim Traoré, Seidina A. S. Diakité, Sékou Bah, Drissa Konaté, Djénéba Dabitao, Ibrahim Sanogo, Modibo Sangaré, Souleymane Dama, Bourama Keïta, Mory Doumbouya, Merepen A. Guindo, Seydou Doumbia, Mahamadou Diakité,
In 2006, the National Malaria Control Program in Mali recommended artemisinin-based combination therapy as the first-line treatment for uncomplicated malaria. Since the introduction of artemisinin-based combination therapy, few reports are available on the level of resistance of Plasmodium falciparum to the most common anti-malarial drugs in Mali. From 2016 to 2017, we assessed the ex-vivo drug sensitivity of P. falciparum isolates in Kéniéroba, a village located in a rural area of southern Mali. ...
Tópico(s): Mosquito-borne diseases and control
2020 - Adis, Springer Healthcare | Drugs in R&D
Amadou Kassogué, Idrissa Sissoko, Daouda Sangaré, Moussa Diallo, Hamed Sylla, Mahamadou Traoré, Boureima Coulibaly, Salia Coulibaly, M. L Diakité, Modibo Togola, Fadima Tall, Ilias Guindo, Ben Naoum Kamel, Mamadou Diakité,
Introduction: Ureteroscopy is a minimally invasive endoscopic surgery which provides access to the ureter, pyelon and calyceal cavities via the urethra and the bladder. Laser ureteroscopy uses the laser as an energy source to treat the stone and eliminate it naturally. Minimally invasive endoscopic methods are struggling to become popular in sub-Saharan African countries, especially for the upper urinary tract. The objective of our work was to report the results of our first laser ureteroscopy experience ...
Tópico(s): Gallbladder and Bile Duct Disorders
2024 - Scientific Research Publishing | Open Journal of Urology
Amagana Dolo, B. Maïga, A. Guindo, Seidina A. S. Diakité, M. Diakite, Amadou Tapily, Mohamed Traoré, B. Sangaré, Charles Arama, Modibo Daou, O Doumbo,
Cette étude avait pour objectif de déterminer la fréquence du déficit en G6PD érythrocytaire (A-376/202)dans trois groupes ethniques au Mali et de vérifier si cette fréquence observée chez les Peulh expliquerait leur protection particulière précédemment décrite contre le paludisme. Les études ont été menées au Mali, en zone sahélienne où les Dogon et les Peulh vivent en sympatrie, puis en zone de savane soudanienne dans une population de Malinké. L'échantillon d'étude était constitué de 90 Dogon, ...
Tópico(s): Biochemical and Molecular Research
2014 - Springer Science+Business Media | Bulletin de la Société de pathologie exotique
A Togo, Y. Coulibaly, Modibo Keita, Abdoulaye Traoré, L Kanté, I. Diakité, Benoit Dembélé, A Maïga, S. Diallo, Mohamed Traoré, Gayo Diallo,
Déterminer la fréquence des infections nosocomiales, identifier leurs facteurs de risque et déterminer les germes en cause et leurs sensibilités. Il s’agissait d’une étude prospective réalisée de 1er janvier au 31 décembre 2007 sur tous les patients hospitalisés dans le service de chirurgie pédiatrique pendant au moins 48 heures. Les enfants dont l’hospitalisation était inférieure à 48 heures et les patients perdus de vue n’ont pas été inclus. L’infection nosocomiale a été identifiée selon les critères ...
Tópico(s): Urinary Tract Infections Management
2009 - Elsevier BV | Journal de Pédiatrie et de Puériculture
Karim Traoré, Bourama Keïta, Abdouramane Traoré, Ibrahim Sanogo, Fatoumata Diarra, Drissa Konaté, Modibo Sangaré, Seidina AS. Diakité, Sékou Bah, Mahamadou Diakité,
Opioids are medications with analgesic properties used primarily as painkillers. Nowadays, off-label uses (non-medical use, prolonged use, misuse and use without a medical supervision) are common inducing drug dependence with harmful consequences including substance-induced psychosis or pharmacopsychosis. In a cross-sectional study from February to June 2021, we used a questionnaire to collect information on the knowledge of interns and doctors trained in the Faculty of Medicine and Dental Medicine ...
Tópico(s): Pharmaceutical Practices and Patient Outcomes
2024 - Society of Pharmaceutical Tecnocrats | Journal of Drug Delivery and Therapeutics
Modibo Sangaré, Fatoumata Doumbia, Oumar Sidibé, Aboubacar Alassane Oumar, Sékou Bah, Modibo Kouyate, Seidina S. Diakite, Karim Traoré, Adama Karembe, Mohamed S Haidara, Souleymane Papa Coulibaly, Souleymane Papa Coulibaly, Arouna Togora, Housseini Dolo, Drissa Traoré, Seydou Doumbia, Mahamadou Diakité, Youssoufa Maiga, Amadou Diawara, Callixte Kuaté, Hyung‐Goo Kim, Gordon A. Awandare,
Background and Purpose:The indication and benefit of plasma level of antiepileptic (AEDs) has been debating in the monitoring of people living with epilepsy and the epilepsy treatment gap has largely been documented in developed countries.This study was aimed to highlight the epilepsy treatment gap between rural and urban Mali.Methods: We conducted a pilot study on AEDs treatment from September 2016 to May 2019.For 6 months, 120 children and young adults living with epilepsy (rural site, 90; urban ...
Tópico(s): Drug Transport and Resistance Mechanisms
2020 - | Journal of Epilepsy Research
Amagana Dolo, Boubacar Maïga, Abdoulaye Guindo, Seidina A. S. Diakité, Mandiou Diakité, Amadou Tapily, Maminata Traoré, B. Sangaré, Charles Arama, Modibo Daou, O Doumbo,
Erythrocyte G6PD deficiency is the most common worldwide enzymopathy. The aim of this study was to determine erythrocyte G6PD deficiency in 3 ethnic groups of Mali and to investigate whether erythrocyte G6PD deficiency was associated to the observed protection against malaria seen in Fulani ethnic group. The study was conducted in two different areas of Mali: in the Sahel region of Mopti where Fulani and Dogon live as sympatric ethnic groups and in the Sudanese savannah area where lives mostly the ...
Tópico(s): Blood disorders and treatments
2014 - Springer Science+Business Media | Bulletin de la Société de pathologie exotique
Mahamadou Ballo, Karim Traoré, S Sidibé, Seidina A. S. Diakité, Abdoulaye Guindo, Fatoumata Daou, Modibo Sangaré, Drissa Konaté, Mahamadou Diakité, Estelle Youl, Sékou Bah,
Malaria infections in pregnancy should be treated promptly with safe and efficacious antimalarial drugs to prevent harmful effects on the mother and fetus. To succeed, the Malian has developed NMCP guidelines for the management of malaria cases in pregnant women. The study aimed at the analysis of the prescription of antimalarial drugs based on the Mali's NMCP guidelines. We conducted a cross-sectional study during malaria transmission season from June to August 2020. The sampling concerned all ...
Tópico(s): Healthcare Systems and Practices
2021 - Society of Pharmaceutical Tecnocrats | Journal of Drug Delivery and Therapeutics
Martin Faye, Ndack Ndiaye, Etienne Kouame Kouadjo, Seydou Camara, Sékou Solano, Ousmane Kébé, Niouma Nestor, Balkissa Modibo, D. Keita, Bangaly Diakité, K Sidibé, Mouctar Kande, Dadja Essoya Landoh, Mohamed Sylla, Sadou Sow, Annick Dosseh, Julius Ebua Chia, Ousmane M. Diop, Abdourahmane Sow, Ndongo Dia, Amadou Alpha Sall, Guéladio Cissé, Ousmane Faye, Kfuthwah Anfumbom, Jean Marie Kipela,
Tópico(s): SARS-CoV-2 and COVID-19 Research
2025 - Elsevier BV | The Lancet Infectious Diseases
Tounkara Idrissa, Diarra Abdoulaye, Traoré Amadou, Coulibaly B. Bakary, Abdoulaye Kanté, Dembélé Dabéré Ives, Souleymane Thiam, Ouattara Kassoum, Kanté Lassana, Madiassa Konaté, Assitan Koné, Oumar Ongoïba, Sangaré Modibo, Dembélé Bakary Tiètiki, Diakité Ibrahim, Sidibé Boubacar Yoro, Amadou Bah, Yakaria Coulibaly, Togo Adégné, Diallo Gangaly,
The diverticulum of the female urethra or sub-urethral pouch is in the form of a cul-de-sac lined with mucous membrane through the muscular layer of the urethra. Thus, it is a site of stasis, urinary infection, formation of calculus or even malignant tumor. The diverticula of the urethra or sub-urethral pouches in women have a prevalence of 0.5% to 6% depending on the series. We report the case of a 61-year-old patient operated for a diverticulum on fistulized urethra complicated lithiasis. Our ...
Tópico(s): Urologic and reproductive health conditions
2019 - Scientific Research Publishing | Surgical Science
Tounkara Idrissa, Diarra Abdoulaye, Traoré Amadou, Coulibaly B. Bakary, Abdoulaye Kanté, Dembélé Dabéré Ives, Souleymane Thiam, Ouattara Kassoum, Kanté Lassana, Madiassa Konaté, Assitan Koné, Oumar Ongoïba, Sangaré Modibo, Dembélé Bakary Tiètiki, Diakité Ibrahim, Sidibé Boubacar Yoro, Amadou Bah, Yakaria Coulibaly, Togo Adégné, Diallo Gangaly,
Umbilical endometriosis, also called Villar’s nodule, has rarely been described in the literature. It represents only 0.5% to 1% of all cases of endometriosis. We report a case in a 28-year-old nulligest, nulliparous woman who consulted at the CSREF CII in Bamako. The diagnosis was suspected with the presence of umbilical swelling with cyclic, painful, dark hemorrhage of firm consistency. We performed an omphalectomy with an uncomplicated postoperative course. She was released from the hospital ...
Tópico(s): Endometriosis Research and Treatment
2019 - Scientific Research Publishing | Surgical Science
Issaka Sagara, Abdoul Habib Béavogui, Issaka Zongo, Issiaka Soulama, Isabelle Borghini-Fuhrer, Bakary Fofana, Aliou Traoré, Nouhoum Diallo, Hamadoun Diakité, Amadou Hamidou Togo, Sekou Koumaré, Mohamed Kéïta, Daouda Camara, Anyirékun Fabrice Somé, Aboubacar Coulibaly, Oumar Traoré, Souleymane Dama, Siaka Goïta, Moussa Djimdé, Amadou Bamadio, Niawanlou Dara, Hamma Maiga, Bouran Sidibé, François Dao, Moctar Coulibaly, Mohamed Lamine Alhousseini, Hamidou Niangaly, Boubou Sangare, Modibo Diarra, Samba Coumaré, Moïse Kaboré, San Maurice Ouattara, Aïssata Barry, Désiré Kargougou, Amidou Diarra, Noelie Henry, Soré Harouna, Edith C. Bougouma, Ismaila Théra, Yves Daniel Compaoré, Colin J. Sutherland, Malick Minkael Sylla, Frédéric Nikièma, Alpha Diallo, Alassane Dicko, Stéphane Picot, Steffen Borrmann, Stephan Duparc, Robert M. Miller, Ogobara K. Doumbo, Jangsik Shin, José Pedro Gil, Anders Björkman, Jean‐Bosco Ouédraogo, Sodiomon B. Sirima, Abdoulaye Djimdé,
Artemether-lumefantrine and artesunate-amodiaquine are used as first-line artemisinin-based combination therapies (ACTs) in west Africa. Pyronaridine-artesunate and dihydroartemisinin-piperaquine are potentially useful for diversification of ACTs in this region, but further safety and efficacy data are required on malaria retreatment.We did a randomised, multicentre, open-label, longitudinal, controlled phase 3b/4 clinical trial at seven tertiary centres in Burkina Faso, Guinea, and Mali. Eligible ...
Tópico(s): Computational Drug Discovery Methods
2018 - Elsevier BV | The Lancet