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Artigo Acesso aberto Revisado por pares

Davide Tanasi, Robert H. Tykot, Frederick Pirone, Erin McKendry,

... Castelluccian Ware (EBA), and Maltese style Borġ in-Nadur wares were recovered with local Thapsos ceramics (MBA). ... including new examples of Thermi and Borġ in-Nadur wares as well as large amounts of Castelluccian ... produced and three out of four Borġ in-Nadur pieces had a Maltese provenance while one of ...

Tópico(s): Archaeological Research and Protection

2017 - De Gruyter Open | Open Archaeology

Artigo Revisado por pares

Richard Franke,

... household survey in the central Kerala village of Nadur from 1971 (just before the reform was implemented), ...

Tópico(s): Agricultural Economics and Practices

1992 - University of Chicago Press | Journal of Anthropological Research

Artigo Revisado por pares

David Trump,

... correspondingly named after the Tarxien Cemetery, Borġ in-Nadur and Baħrija. In 1956, Evans published a more ... as the only excavations were at Borġ in-Nadur in 1881 (a sketch plan found in a ...

Tópico(s): Historical and Architectural Studies

1961 - Cambridge University Press | Proceedings of the Prehistoric Society

Artigo Acesso aberto Revisado por pares

Jon P. Mitchell,

... on the Neolithic temple site of Borġ-in-Nadur, in Southern Malta, which as well as having ... paper suggests that sites such as Borġ-in-Nadur can be seen as palimpsest landscapes, in which ... Catholic and Neo-pagan engagements with Borġ-in-Nadur, extending Pierre Nora's concept of lieux de ...

Tópico(s): Geographies of human-animal interactions

2020 - Taylor & Francis | Material Religion

Artigo Acesso aberto Revisado por pares

Davide Tanasi, Annamaria Cucina, Vincenzo Cunsolo, Rosaria Saletti, Antonella Di Francesco, Enrico Greco, Salvatore Foti,

... as the final part of the Borġ in-Nadur culture. Proteomic data here reported confirm that one ...

Tópico(s): Maritime and Coastal Archaeology

2021 - Springer Science+Business Media | Amino Acids

Artigo Acesso aberto Revisado por pares

Edgar Carnero Contentti, Pablo A. López, Juan Pablo Pettinicchi, Juan Criniti, Agustín Pappolla, Jimena Míguez, Liliana Patrucco, Edgardo Cristiano, Susana Liwacki, Verónica Tkachuk, María Eugenia Balbuena, Cárlos Vrech, Norma Deri, Jorge Correale, Mariano Marrodán, María Célica Ysrraelit, Felisa Leguizamón, Geraldine Luetic, María Laura Menichini, Darío Tavolini, Carolina Mainella, Gisela Zanga, Marcos Burgos, Javier Hryb, Andrés Barboza, Luciana Lázaro, Ricardo Alonso, Nora Fernández Liguori, Débora Nadur, Aníbal Chertcoff, Ricardo Alonso, Alejandro Caride, Friedemann Paul, Juan Ignacio Rojas,

We aimed to examine treatment interventions implemented in patients experiencing neuromyelitis optica spectrum disorders (NMOSD) attacks (frequency, types, and response). Methods Retrospective study. Data on patient demographic, clinical and radiological findings, and administered treatments were collected. Remission status (complete [CR], partial [PR], no remission [NR]), based on changes in the EDSS score was evaluated before treatment, during attack, and at 6 months. CR was analyzed with a generalized ...

Tópico(s): Systemic Lupus Erythematosus Research

2021 - SAGE Publishing | Multiple Sclerosis Journal - Experimental Translational and Clinical

Revisão Brasil Produção Nacional Revisado por pares

Nathália Fonseca Nadur, Luciana Luiz de Azevedo, Lucas Caruso, Cedric Stephan Graebin, Renata Barbosa Lacerda, Arthur Eugen Kümmerle,

Cyclic nucleotide phosphodiesterases (PDEs) are a superfamily of enzymes known to play a critical role in the indirect regulation of several intracellular metabolism pathways through the selective hydrolysis of the phosphodiester bonds of specific second messenger substrates such as cAMP (3',5'-cyclic adenosine monophosphate) and cGMP (3',5'-cyclic guanosine monophosphate), influencing the hypertrophy, contractility, apoptosis and fibroses in the cardiovascular system. The expression and/or activity ...

Tópico(s): Cholinesterase and Neurodegenerative Diseases

2020 - Elsevier BV | European Journal of Medicinal Chemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Matheus de Freitas Silva, Ellen Tardelli Faleiros Lima, Letizia Pruccoli, Newton G. Castro, Marcos Jorge R. Guimarães, Fernanda da Silva, Nathália Fonseca Nadur, Luciana de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent E. Dardenne, Vanessa Silva Gontijo, Andrea Tarozzi, Cláudio Viegas,

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder that involves different pathogenic mechanisms. In this regard, the goal of this study was the design and synthesis of new compounds with multifunctional pharmacological activity by molecular hybridization of structural fragments of curcumin and resveratrol connected by an N-acyl-hydrazone function linked to a 1,4-disubstituted triazole system. Among these hybrid compounds, derivative 3e showed the ability to inhibit acetylcholinesterase ...

Tópico(s): Alzheimer's disease research and treatments

2020 - Multidisciplinary Digital Publishing Institute | Molecules

Artigo Brasil Produção Nacional Revisado por pares

Gabriela Russo Soeiro Campos, Kátia Margareth Bitton de Moura, Ana Maria Barbosa, Luis Fernando Zamuner, Nikele Nadur‐Andrade, Camila Squarzoni Dale, José Marı́a Gutiérrez, Maria Cristina Chavantes, Stella Regina Zamunér,

The therapeutic effect of the Light Emitting Diode (LED) treatment in two wavelengths (635 or 945 nm) was evaluated in the local pathological alterations induced by Bothrops asper snake venom. Mice received irradiation of infrared LED (120 mW, 945 nm) or red LED (110 mW, 635 nm) applied immediately, 1 and 2 h after venom injection. LED treatment reduced edema formation in the plantar region and gastrocnemius muscle and significantly reduced neutrophil migration and hyperalgesia after the venom injection. ...

Tópico(s): Marine Invertebrate Physiology and Ecology

2018 - Elsevier BV | Toxicon

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Nikele Nadur‐Andrade, Camila Squarzoni Dale, Victória Regina da Silva Oliveira, Elaine F. Toniolo, Regiane dos Santos Feliciano, José Antônio Silva, Stella Regina Zamunér,

Envenoming induced by Bothrops snakebites is characterized by drastic local tissue damage that involves an intense inflammatory reaction and local hyperalgesia which are not neutralized by conventional antivenom treatment. Herein, the effectiveness of photobiomodulation to reduce inflammatory hyperalgesia induced by Bothrops moojeni venom (Bmv), as well as the mechanisms involved was investigated.Bmv (1 μg) was injected through the intraplantar route in the right hind paw of mice. Mechanical hyperalgesia ...

Tópico(s): Laser Applications in Dentistry and Medicine

2016 - Public Library of Science | PLoS neglected tropical diseases

Artigo Acesso aberto

Zuzana Čarnická, Branislav Kollár, Pavel Šiarnik, Lucia Krížová, Katarína Klobučníková, Peter Turčáni,

... Multiple Sclerosis in ArgentinaCarnero Contentti E, López P, Nadur D, Balbuena M, Finkelstein A and Tkachuk V ...

Tópico(s): Vestibular and auditory disorders

2015 - American Academy of Sleep Medicine | Journal of Clinical Sleep Medicine

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Nikele Nadur‐Andrade, Camila Squarzoni Dale, Adriano Silvio dos Santos, Andreimar M. Soares, Carlos José de Lima, Stella Regina Zamunér,

The prominent local myotoxic effects induced by Bothrops snake venom are due, in part, to myotoxins This effect is not neutralized by antivenom, which is the main therapy for victims of snakebite. Two basic myotoxins named MjTX-I and MjTX-II were isolated from Bothrops moojeni venom. Both myotoxins have a Lys-49 phospholipase A2 structure devoid of enzymatic activity, but are highly myonecrotic and edema-inducing. In this study, we analyzed the effect of a low-level laser (LLL) at 685 nm, an energy ...

Tópico(s): Neurobiology and Insect Physiology Research

2014 - Springer Science+Business Media | Photochemical & Photobiological Sciences

Artigo Brasil Produção Nacional Revisado por pares

Nikele Nadur‐Andrade, Stella Regina Zamunér, Elaine F. Toniolo, Carlos José de Lima, José Carlos Cogo, Camila Squarzoni Dale,

Envenoming induced by Bothrops snakes is characterized by drastic local tissue damage involving hemorrhage, myonecrosis and proeminent inflammatory and hyperalgesic response. The most effective treatment is antivenom therapy, which is ineffective in neutralizing the local response. Herein, it was evaluated the effectiveness of light-emitting diode (LED) at wavelengths of 635 and 945 nm in reducing inflammatory hyperalgesia induced by Bothrops moojeni venom (BmV) in mice, produced by an subplantar ...

Tópico(s): Entomological Studies and Ecology

2013 - Wiley | Photochemistry and Photobiology

Artigo Acesso aberto Revisado por pares

Filippo Stanco, Davide Tanasi,

... of a virtual reconstruction of the Borg in-Nadur megalithic temple, carried out by Archeomatica Project of ...

Tópico(s): Archaeological Research and Protection

2013 - Hindawi Publishing Corporation | Journal of Electrical and Computer Engineering

Artigo Brasil Produção Nacional

Ludmila Guimarães Souza, Camila Squarzoni Dale, Nikele Nadur‐Andrade, Ana Maria Barbosa, José Carlos Cogo, Stella Regina Zamunér,

Tópico(s): Entomological Studies and Ecology

2012 - International Scientific Information Inc. | Clinical and Experimental Medical Letters

Artigo Brasil Produção Nacional Revisado por pares

Simone Nadur Motta Leduc, João Paulo Naldi Silva, Marı́lia Gaspar, Cláudio José Barbedo, Rita de Cássia L. Figueiredo-Ribeiro,

Seeds of Caesalpinia echinata fill up to physiological maturation phase ~60 days after anthesis (DAA) in the field. These seeds are desiccation tolerant to 0.08 gH2O gDW–1 and can be stored for 2 years under freezing temperatures without losing germinability. Starch (40–50%), soluble carbohydrates (10–15%, mainly sucrose and cyclitols), in addition to traces of raffinose and stachyose detected early at maturation, are supposed to be related to the acquisition of desiccation tolerance. In the present ...

Tópico(s): Plant Stress Responses and Tolerance

2012 - CSIRO Publishing | Australian Journal of Botany

Artigo Brasil Produção Nacional Revisado por pares

Nikele Nadur‐Andrade, Ana Maria Barbosa, Fernando Pereira Carlos, Carlos José de Lima, José Carlos Cogo, Stella Regina Zamunér,

Tópico(s): Healthcare and Venom Research

2011 - Springer Science+Business Media | Lasers in Medical Science

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Edmir Vicente Lamarca, Simone Nadur Mota Leduc, Cláudio José Barbedo,

O teste de tetrazólio é importante componente para a avaliação da qualidade fisiológica de sementes, possibilitando fornecer rápida avaliação do vigor e do estado de deterioração. Objetivou-se desenvolver metodologia do teste de tetrazólio para sementes de Caesalpinia echinata Lam. (pau-brasil). Sementes colhidas por ocasião de sua maturidade fisiológica foram incubadas, com ou sem tegumento, em soluções de tetrazólio em concentrações que variaram de 0,05% a 1,00%, por períodos que variaram de 1 ...

Tópico(s): Agricultural and Food Sciences

2009 - Springer Science+Business Media | Revista Brasileira de Botânica

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Anna Laeticia Trindade Barbosa, Ricardo Junqueira Del Carlo, Hayala Castro Gomes, Aécio Carlos de Oliveira, Betânia Souza Monteiro, Brunna Nadur Del Carlo,

As plaquetas chegam rapidamente ao local da ferida e liberam múltiplos fatores de crescimento (FC) e citocinas que contribuem para a reparação óssea e aumentam a vascularização local. O Plasma Rico em Plaquetas (PRP) concentra as plaquetas e os FC liberados por elas, aceleram a formação óssea e melhora a qualidade do trabeculado. Este trabalho apresenta um protocolo para confecção de PRP e demonstra alguns aspectos da sua utilização na reparação óssea de cães. O protocolo foi desenvolvido a partir ...

Tópico(s): Dental Implant Techniques and Outcomes

2008 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural

Revisão Acesso aberto Revisado por pares

P. R. Shashank, Nadur L. Naveena, N. N. RAJGOPAL, Tyler A. Elliott, Kolla Sreedevi, Sunil Sunil, Naresh M. Meshram,

Insect fauna occupy the largest proportion of animal biodiversity on earth, but the assessment or quantification in terms of species diversity is far from complete. Several recent studies have demonstrated the rapid pace at which insect population decline is occurring. There is an urgent need to document and quantify the diversity of insect fauna for a proper understanding of terrestrial ecosystems. This can be achieved by using modern technology to identify species much faster than relying on traditional ...

Tópico(s): Plant and animal studies

2022 - Springer Nature | Molecular Biology Reports

Artigo Revisado por pares

Simona Raneri, Germana Barone, Paolo Mazzoleni, Davide Tanasi, Emanuele Costa,

... Middle Bronze Age pottery of Malta (Borġ in-Nadur, half of 15th – early 12th century BC) to ...

Tópico(s): Archaeology and ancient environmental studies

2015 - | Periodico di mineralogia

Artigo

M. A. Murray,

Tópico(s): Metallurgy and Cultural Artifacts

1923 - Royal Anthropological Institute of Great Britain and Ireland | Man

Artigo Brasil Produção Nacional Revisado por pares

Edgar Carnero Contentti, Pablo A. López, Juan Criniti, Juan Pablo Pettinicchi, Edgardo Cristiano, Liliana Patrucco, Elisa Bribiesca Contreras, Enrique Gómez‐Figueroa, José Flores‐Rivera, Edgar Patricio Correa‐Díaz, Ana María Toral Granda, Maria Yepez, Wilson Alfredo Gualotuña Pachacama, Jefferson Santiago Piedra Andrade, Lorna Galleguillos, Verónica Tkachuk, Débora Nadur, Vanessa Daccach Marques, Ibis Soto de Castillo, Magdalena Casas, Leila Cohen, Ricardo Alonso, Alejandro Caride, Marco Aurélio Lana–Peixoto, Juan Ignacio Rojas,

Optic neuritis (ON) is often the initial symptom of neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein-associated disease (MOGAD). We aimed to compare the frequency and pattern of chiasmatic lesions in MOGAD-related ON (MOGAD-ON) and NMOSD-related ON (NMOSD-ON) using conventional brain imaging (magnetic resonance imaging [MRI]) in Latin America (LATAM).We reviewed the medical records and brain MRI (≤30 days from ON onset) of patients with a first event of MOGAD-ON and NMOSD- ...

Tópico(s): Systemic Lupus Erythematosus Research

2021 - Wiley | European Journal of Neurology

Artigo

Geraldine Luetic, María Laura Menichini, Cárlos Vrech, Agustín Pappolla, Liliana Patrucco, Edgardo Cristiano, Mariano Marrodán, María Célica Ysrraelit, Marcela Fiol, Jorge Correale, Leila Cohen, Ricardo Alonso, Berenice Silva, Magdalena Casas, Orlando Garcea, Norma Deri, Marcos Burgos, Susana Liwacki, Verónica Tkachuk, Andrés Barboza, Raúl Piedrabuena, Patricio Blaya, Judith Steinberg, Alejandra Martínez, Adriana Carrá, Darío Tavolini, Pablo A. López, Eduardo Knorre, Pedro Nofal, Gabriel Volman, Edgar Carnero Contentti, Amelia Alves Pinheiro, Felisa Leguizamón, Emanuel Silva, Javier Hryb, María Eugenia Balbuena, Gisela Zanga, Matías Kohler, Aníbal Chertcoff, Luciana Lázaro, Santiago Tizio, Carolina Mainela, Edgardo Reich, Luciano Recchia, Jorge Blanche, Marcela Parada Marcilla, María E. Fracaro, Gustavo Sgrilli, Pablo Divi, Miguel Jacobo, Mariela Cabrera, Fátima Pagani Cassara, Vladimiro Sinay, Celeste Curbelo, Jimena Míguez, Mariano Coppola, Nora Fernández Liguori, Iván Martos, Juan Pablo Pettinicchi, Juan Pablo Viglione, Gustavo José, Santiago Bestoso, Rubén Manzi, Guido Vázquez, Débora Nadur, Carlos Martínez, Ricardo Alonso, Juan Ignacio Rojas,

In multiple sclerosis demographics there is a well-known female prevalence and male patients have been less specifically evaluated in clinical studies, though some clinical differences have been reported between sexes.The objective of this study was to assess clinical and demographic differences between male and female patients included in the national Argentine MS Registry-RelevarEM.This study was observational, retrospective, and was based on the data of 3099 MS patients included as of 04 April ...

Tópico(s): Rheumatoid Arthritis Research and Therapies

2021 - Elsevier BV | Multiple Sclerosis and Related Disorders

Artigo Acesso aberto

Gustavo Plotnikow, Amelia Matesa, Juan Nadur, Marcelo Alonso, Ignacio García Núñez, Gabriel Vergara, Maria J. Alfageme, Agustin Vitale, Marco Gil, Valeria Kinzler, Marianela Melia, Florencia Pugliese, Mariana Donnianni, Joana Pochettino, Ignacio Brozzi, José Luis Scapellato,

OBJECTIVE: A novel coronavirus emerged this year as a cause of viral pneumonia. The main characteristics of the virus are rapid transmission, high contagion capacity and potential severity. The objective of this case series study is to describe the clinical characteristics of patients with confirmed coronavirus disease (COVID-19) admitted to different intensive care units in Argentina for mechanical ventilation. METHODS: A descriptive, prospective, multicenter case series study was conducted between ...

Tópico(s): SARS-CoV-2 and COVID-19 Research

2020 - Associação de Medicina Intensiva Brasileira | Revista Brasileira de Terapia Intensiva

Revisão Brasil Produção Nacional Revisado por pares

Lucas Caruso, Nathália Fonseca Nadur, Marina Brandão da Fonseca, Larissa A. Ferreira, Renata Barbosa Lacerda, Cedric Stephan Graebin, Arthur Eugen Kümmerle,

Abstract: Cardiovascular diseases (CVDs) comprise a group of diseases and disorders of the heart and blood vessels, which together are the number one cause of death worldwide, being associated with multiple genetic and modifiable risk factors, and that may directly arise from different etiologies. For a long time, the search for cardiovascular drugs was based on the old paradigm “one compound - one target”, aiming to obtain a highly potent and selective molecule with only one desired molecular target. ...

Tópico(s): Receptor Mechanisms and Signaling

2022 - Bentham Science Publishers | Current Topics in Medicinal Chemistry

Artigo Revisado por pares

Edgar Carnero Contentti, Pablo A. López, Verónica Tkachuk, Cárlos Vrech, María Agustina Zárate, Jorge Correale, Norma Deri, Geraldine Luetic, Mariano Marrodán, Fátima Pagani Cassara, Darío Tavolini, María Célica Ysrraelit, María Eugenia Balbuena, Javier Hryb, Edson Chiganer, Felisa Leguizamón, Eduardo Knorre, Gisela Zanga, Claudia Pestchanker, Andrés Barboza, Débora Nadur, Edgardo Cristiano, Liliana Patrucco, Ricardo Alonso, Ricardo Alonso, Friedemann Paul, Juan Ignacio Rojas,

We aimed to assess the frequency of new asymptomatic lesions on brain and spinal imaging (magnetic resonance imaging (MRI)) and their association with subsequent relapses in a large cohort of neuromyelitis optica spectrum disorder (NMOSD) patients in Argentina.We retrospectively reviewed 675 MRI (225 performed during an attack and 450 during the relapse-free period (performed at least 3 months from the last attack)) of NMOSD patients who had at least 2 years of clinical and MRI follow-up since disease ...

Tópico(s): Systemic Lupus Erythematosus Research

2023 - SAGE Publishing | Multiple Sclerosis Journal

Artigo Acesso aberto Revisado por pares

Edgar Carnero Contentti, Pablo A. López, Débora Nadur, María Eugenia Balbuena, Ana Mariel Finkelstein, Verónica Tkachuk,

Restless legs syndrome (RLS) frequency, and its association with depression, anxiety, sleep disorders, and fatigue, has not been previously studied in Latin American patients with multiple sclerosis (MS). We aimed to assess RLS frequency in patients with MS living in Argentina and to examine potential associations with depression, anxiety, and sleep disorders.A cross-sectional study (n = 427) was conducted using a self-administered questionnaire, including International RLS Study Group criteria, to compare ...

Tópico(s): Sleep and Wakefulness Research

2018 - | International Journal of MS Care