Andrew Robson, Terence Wilkerson, Jon Ashworth, Raymond Snoddy Media Editor, Alicia Collinson, Charles Darwin, Carl Philpott, Robert Cole, Nick Turner, Nigel Hawkes and David Charter, Joy Kay, DJM, James Moore, Adam Sherwin Media Reporter, Sarah Potter, Frances Gibb Legal Editor, Judy Linton, Neil Inkley, Magnus Linklater, John Phillips and Dragan Petrovic, Philip Webster Political Editor and Lea Paterson Economics Editor, Our Sports Staff, Mark Souster, Richard Hobson, Philip Howard, Ian Cobain, David Chater, Tracy Ruddle, Helen Rambelow, Alexandra Frean Social Affairs Correspondent, Elizabeth Judge, Lisa Crooks, Richard Irving, Gabrielle Starkey, Barbara Ellen, Richard Heaslip, Geoff Brown, Sam Lister, Irwin Stelzer, Caroline Gluck, Andrew Norfolk, John O'Leary Education Editor, Joe Joseph, Antonia Senior, Jason Roach, medical student, Ben Webster Transport Correspondent, Pat Gibson, Valerie Elliott Countryside Editor, David McVay, Steve Keenan, Stewart Tendler Crime Correspondent, Ian Lamont, Jack Malvern, Dominic Walsh, Shirley English, Ian Timberlake, John Bithell, John Street, Tim Reid, Daniel Finkelstein, Richard Ford Home Correspondent, Stephen Farrell, Oliver Wright, Robin Young, Michael Backman, Jenny MacArthur, Anatole Kaletsky, Julian Elliott, Valentin Dobrev, David Hands, P. B., Charles Bremner, Christopher Martin Jenkins, Helen Rumbelow, Matt Dickinson Chief Football Correspondent, Helen Nugent and Paula Hawkins, David Charter, Mark Court, Patience Wheatcroft Business Editor, Derwent May, Caroline Merrell Banking Correspondent, Stuart Crainer, Angela Jameson, William Shawcross, Kate Muir, Dr Stuttaford, Fiona Cameron, Peter Paphides, Robert Cole City Correspondent, Vanora Bennett, Mark Tweedle, Oliver Kay, Dora Carrington, Mark Atherton, Rick Broadbent, Abe Rhodes, Stephen Burgen, Mark Henderson Science Correspondent, Jill Sherman Whitehall Editor, Sam Coates, Michael Horsnell and Ruth Gledhill, Peter Wheeler, Simon de Bruxelles, Sean Macaulay, Rob Wright, Geoffrey Dean, Neil Harman Tennis Correspondent, David Powell Athletics Correspondent, Raymond Keene, Rebecca Naden, Adam Sage, Lewis Smith, Patrick Wolf, Richard Pohle, Philip Whiteley, Dr John Canning, General Practitioner, William Swadling, Tamsin Forman, Chris Partridge, H. M. Debenham, Greg Hurst Parliamentary Correspondent, Nigel Hawkes, Peta Bee, Martin Winter, Bronwen Maddox, Russell Hotten, Jill Sherman, Richard Owen, Damian Whitworth, Donald Haigh, Ruth Taplin, Parviz Habibi, Oliver August, Nick Hasell, Stewart Tendler, Ashley Mote, Tom Venables, Alan Hamilton and Claire McDonald, Paul Simons, Anne Ashworth, John Goodbody, James Doran, Melissa Kite Political Correspondent, Tim Hames, Ian Johns, Kevin McCarra, Mike Rosewell, Chris McGrath, George Caulkin, Alan Lee, Marion Crawford, Anthony Loyd, Peter Riddell, Lea Paterson Economics Editor, Mark Court Health Industries Correspondent, Vicky Flett, John Goodbody Sports News Correspondent, Dominic Walsh and Jon Ashworth, Tony Dawe, Richard Beeston Diplomatic Editor, Ben Macintyre, David Charter Chief Political Correspondent, Michael Dynes, Veronica Kirby, Gary Duncan Economics Correspondent, Martin Waller, B. Cymerman, Michael Horsnell, Chris Ayres, Carl Mortished International Business Editor, Peter Gardner, Laura Peek, Nigel Hawkes Health Editor, Daniel Rosenthal, Benedict Nightingale, Michael Rich, Linsey McNeill, Jonathan Meades, Dr Thomas Stuttaford, Stephen Dalton, David Harounoff, Bill Edgar, Richard Morrison, Tom Chesshyre, James Christopher, Alice Miles, Susan MacDonald, Tom Baldwin Deputy Political Editor, Larry Rushton, George Steele, Sally Patten, John Rippier, Jan Raath, Edward Gorman Sailing Correspondent, David Hands, Rugby Correspondent, Chris Brasher, Sally Patten Retail Correspondent, Patience Wheatcroft, Jim Sillars, Janine di Giovanni, Susan Emmett, David Lister Ireland Correspondent,
... inspired letter-writer, lived in a singular m?nage ? trois with Ralph Partridge and Lytton Strachey, to ...
2002 - Gale Group | TDA
Michael J. Rogers, Tadaaki Ohgi, Jackie Plumbridge, Dieter Söil,
... acetylglucosamine (GlcNAc) uptake and metabolism (nagA, nagB, and nagE) are located next to glutaminyl-tRNA synthetase gene ( ... genome. We determined the nucleotide sequence of the nagE (ptsN) gene, encoding the GlcNAc-specific enzyme II (NagE) of the phosphoenolpyruvate: sugar phosphotransferase system, and the ... S 1 mapping identified the mRNA transcript for nagE, indicating that nagE might be a sole constituent of the nagE operon, and divergent transcripts which are probably of ... evaluation of the hydrophobic and hydrophilic properties of NagE shows characteristics of a membrane protein. Also, NagE ...
Tópico(s): RNA and protein synthesis mechanisms
1988 - Elsevier BV | Gene
Tung‐Kwang Lee, Kevin O’Brien, Weidong Wang, Chao Sheng, Tao Wang, Roberta M. Johnke, Ron R. Allison,
... impact of a standardized North American ginseng extract (NAGE) on 137 Cs-induced oxidative stress in human ... h and 24 h before irradiation), we applied NAGE (250 -1000 µg ml -1 ) to mononuclear cell ... PBL.We found that at both time points, NAGE significantly reduced the MN yields in PBL after ... also found that before irradiation the presence of NAGE in the culture medium resulted in a significant ... 0.02 -0.004).However, the presence of NAGE in the culture medium significantly increased the TAC ... in PBL (P<0.001).Our findings that NAGE is effective in protecting human PBL against radiation- ...
Tópico(s): Effects of Radiation Exposure
2009 - Bentham Science Publishers | The Open Nuclear Medicine Journal
Produção Nacional
Revisado por pares
Ramdane Almansba, Émerson Franchini, S Sterkowicz, Rodney Imamura, Michel Calmet, Saı̈d Ahmaı̈di,
... for each subject. In addition, three trials of Nage-komi exercise, each comprised of a set of Osoto-gari (15s), Uchi-mata (15s) and Seoi-nage (15s) throws were performed by each subject to ... throws (p < 0.05) executed during the Seoi-nage (p < 0.01) and Uchi-mata (p < 0. ... the heavier category using the arm technique (Seoi-nage), while the heavier category has more speed using ... pour chaque sujet. En outre, trois essais de Nage-komi, chaque essai est composé d’une série ... Osoto-gari (15s), Uchi-mata (15s) et Seoi-nage (15s) ont été accordés à chaque sujet pour ...
Tópico(s): Sports injuries and prevention
2008 - Elsevier BV | Science & Sports
... pFDY226; lanes 4 and 5, R1279/pFDX3293 (bglG, nagE)/pFDY226; lanes 6 and 7, R1279/pFDX3295 (bglG, ... bglF); lanes 11 and 12, R1279/ pFDX3293 (bglG, nagE)/pFDX3283 (bglF); lanes 13 and 14, R1279/pFDX3295 ( ... 1, 2 and 3, respectively. Neither overexpression of nagE (encoding EIINag) nor that of mtlA (encoding EIIMtl) ... this pattern did not alter, when in addition, nagE (lane 11) or mtlA (lane 13) was expressed ... controlled expression of different EIIs (where indicated): pFDX3297 (nagE; EIINag), pFDX3298 (mtlA; EIIMtl), pFDX3299 (bglF; EIIBgl). Given ...
Tópico(s): Protein Structure and Dynamics
1999 - Springer Nature | The EMBO Journal
... derivatives were overproduced in LM1, a crr and nagE E.coli strain. Membranes were incubated with [32P] ... LM1, a strain deleted for the crr and nagE genes (and thus not expressing the IIAglc and ... strains which are wild-type for crr and nagE (Mahadevan et al., 1987), and also isogenic strains defective in the crr and nagE genes which we have constructed (see Materials and ... F2 C24S 30 36 30 59 PPA546 (crr, nagE) pMN5 wild-type 5 100 3 324 pCQ- ... F2 C24S 68 152 73 133 PPA547 (crr, nagE) pMN5 wild-type 4 82 5 283 pCQ- ...
Tópico(s): RNA and protein synthesis mechanisms
1997 - Springer Nature | The EMBO Journal
Jacqueline Plumbridge, Annie Kolb,
... repressor binds to two sites in the intergenic nagE-B region overlapping the divergently expressed nagE and nagB promoters. In addition the NagC repressor ... advantage of the fact that repression of the nagE and nagB genes requires the formation of a ... between molecules of the repressor bound to the nagE and nagB operators. The nagE operator was systematically mutagenised and the effect of ... with considerably higher affinity than the wide-type nagE operator both in vitro and in vivo, a " ... allow a higher level of repression of the nagE promoter compared to the nagB, presumably due to ...
Tópico(s): RNA Interference and Gene Delivery
1995 - Elsevier BV | Journal of Molecular Biology
Takanori Ishii, Michiyoshi Ae, Yuta Suzuki, Yasuto Kobayashi,
... determine fast and skilful execution of the seoi-nage (shoulder throw) technique by comparing kinematics between elite ... and seven male college judo athletes performed seoi-nage. No significant difference was found in motion phase ... not necessarily a factor contributing quickness in seoi-nage. The maximum relative velocity of the whole body ... drive and turning motion reflects high skill seoi-nage. Coaches should recognise the relative forward velocity as ... factor that may contribute to a successful seoi-nage when teaching the judo throw technique.
Tópico(s): Shoulder Injury and Treatment
2017 - Taylor & Francis | Sports Biomechanics
Alireza Nasirzade, Alireza Ehsanbakhsh, Hamed Argavani, Azade Sobhkhiz, Mahdi Aliakbari,
... nageurs de sexe masculin sur un 50 m nage libre. Différentes caractéristiques anthropométriques ont été mesurées, comme ... été réalisées au cours d'un 50 m nage libre chez 23 jeunes nageurs d'un âge ... à 84 % les meilleures performances au 50 m nage libre. L'architecture musculaire et les caractéristiques anthropométriques expliquent moins complètement les performances en nage libre (respectivement 52 % et 22 %). De même, les ... de la variabilité des performances au 50 m nage libre entre les jeunes nageurs. Les résultats obtenus ...
Tópico(s): Sport Psychology and Performance
2014 - Elsevier BV | Science & Sports
Misagh Alipour, Abdelwahab Omri, Zacharias E. Suntres,
... extract of Panax quinquefolius from North American ginseng (NAGE) root against Pseudomonas aeruginosa . The minimum inhibitory concentrations ... by a standard agar-dilution method. At subinhibitory NAGE concentrations, the secretion of virulence factors, motility on ... O1 strain. At suprainhibitory concentrations, the activity of NAGE against mature biofilm complexes formed in the Calgary ... Device and the Stovall flow cell were assessed. NAGE possessed an antibacterial activity against all the Pseudomonas ...
Tópico(s): Mycobacterium research and diagnosis
2011 - NRC Research Press | Canadian Journal of Physiology and Pharmacology
Tung‐Kwang Lee, Kevin O’Brien, Weidong Wang, Roberta M. Johnke, Chao Sheng, S Benhabib, Tao Wang, Ron R. Allison,
... effect of a standardized North American ginseng extract (NAGE, total ginsenoside content: 11.7%) on DNA damage ... 90 minutes postirradiation. Design: With the application of NAGE (250–1000 μg mL−1) at 90 minutes ... oxygen species (ROS). Results: The significant effect of NAGE against 137Cs-induced micronuclei (MN) in lymphocytes is concentration dependent. NAGE (750 μg mL−1) reduced MN yield by ... of WR-1065. Furthermore, we also found that NAGE reduces MN yield and ROS but increases TAC in lymphocytes. Conclusions: Our results suggest that NAGE is a relatively nontoxic natural compound that holds ...
Tópico(s): Biological Activity of Diterpenoids and Biflavonoids
2010 - Mary Ann Liebert, Inc. | The Journal of Alternative and Complementary Medicine
Tung‐Kwang Lee, Weidong Wang, Kevin O’Brien, Roberta M. Johnke, Tao Wang, Ron R. Allison, Angelica L. Diaz,
... effect of a standardized North American ginseng extract (NAGE) on human peripheral blood lymphocytes (PBL), a micronuclei ( ... was conducted in PBL obtained from 12 volunteers. NAGE (50–1000 µg/mL) and WR‐1065 (1 ... 2) MN yields declined with increasing concentrations of NAGE and WR‐1065. Even at 90 min post‐ ... maximum level of MN reduction rate caused by NAGE and WR‐1065 was 53.8% and 59. ... Poisson distribution in all cases; and (4) both NAGE and WR‐1065 showed no significant effect on ... proliferation index of lymphocytes. The results indicate that NAGE is a relatively non‐toxic natural product, which ...
Tópico(s): DNA Repair Mechanisms
2008 - Wiley | Phytotherapy Research
Thomas K. H. Chang, Jie Chen, Salete Benetton,
... standardized Panax quinquefolius (or North American ginseng) extract (NAGE), and individual ginsenosides (Rb1, Rb2, Rc, Rd, Re, ... assessed by 7-ethoxyresorufin O -dealkylation. G115 and NAGE decreased human recombinant CYP1A1, CYP1A2, and CYP1B1 activities ... the other cases. A striking finding was that NAGE was 45-fold more potent than G115 in inhibiting CYP1A2. Compared with G115, NAGE also preferentially inhibited 7-ethoxyresorufin O -dealkylation activity ... in an inhibitory concentration (100 μg/ml) of NAGE or G115, did not influence CYP1 activities. However, ...
Tópico(s): Traditional Chinese Medicine Analysis
2002 - American Society for Pharmacology and Experimental Therapeutics | Drug Metabolism and Disposition
... system (PTS) genes in Escherichia coli. NagC represses nagE, encoding the N-acetylglucosamine-specific transporter, while Mlc ... for most native NagC sites, but not the nagE operator, which thus looks like a potential Mlc target. The nagE operator does exhibit a higher affinity for Mlc than NagC, but no regulation of nagE by physiological concentrations of Mlc was detected in vivo. Regulation of wild-type nagE by NagC is achieved because of the chelation ...
Tópico(s): Bacteriophages and microbial interactions
2001 - Oxford University Press | Nucleic Acids Research
Repression of the divergent nagE-B operons requires NagC binding to two operators which overlap the nagE and nagB promoters, resulting in formation of a ... CAP activator to its site, adjacent to the nagE operator, stabilizes the DNA loop in vitro. The DNA of the nagE-B intergenic region is intrinsically bent, with the ... CAP complex is necessary for activation of the nagE-B promoters. In this case protein-protein contacts ...
Tópico(s): RNA Interference and Gene Delivery
1998 - Oxford University Press | Nucleic Acids Research
Krishna G. Peri, Hughes Goldie, E. Bruce Waygood,
... utilization in Escherichia coli: enzyme II nag (gene nagE), N-acetylglucosamine-6-phosphate deacetylase (gene nagA), and ... coli strains with mutations in nagA, nagB, and nagE. The gene products from the 5.7-kb ... had the following relative masses (M r s: nagE, 62 000; nagA, 45 000; nagB, 29 000. ... protein binding site that may control nagB and nagE, putative rho-independent terminator sites for nagB and nagE, and sequence homologies for RNA polymerase binding sites ... 40 954; nagB, 29 657; nagC, 44 664; nagE, 68 356. No role is known for nagC, ...
Tópico(s): Carbohydrate Chemistry and Synthesis
1990 - NRC Research Press | Biochemistry and Cell Biology
Wei Dai, Jian Wu, Danyang Wang, Jinke Wang,
... therapy strategy named NF-κB-activated gene expression (Nage), which could induce the death of cancer cells ... cells, but had no effects on normal cells. Nage was consisted of an NF-κB-specific promoter ... then tested the cancer cell specificity of the Nage vector by expressing the reporter gene ZsGreen in ... vitro cultivated cells. We next demonstrated that the Nage vector could be used to express CRISPR/Cas9 ... telomeric DNA and induced cancer cell death. The Nage vector expressing Cas9/sgRNA could be packaged into ...
Tópico(s): RNA Interference and Gene Delivery
2020 - Springer Nature | Gene Therapy
Haruo Murayama, Masahito Hitosugi, Yasuki Motozawa, Masahiro Ogino, Katsuhiro Koyama,
... person thrown forward by the judo technique 'Seoi-nage'. A judo expert threw an anthropomorphic test device ( ... gravity of the dummy's head. When Seoi-nage was performed, the dummy fell forward accompanied by ... angular accelerations in all axes observed in Seoi-nage were high and the resultant value was approximately ... mechanism of acute subdural hematoma caused by Seoi-nage is that a large angular acceleration causes large ...
Tópico(s): Musculoskeletal pain and rehabilitation
2019 - Japan Neurological Society | Neurologia medico-chirurgica
Lavinia M. Scherf, Antti J. Karttunen, Oliver Pecher, Pieter C. M. M. Magusin, Clare P. Grey, Thomas F. Fässler,
Abstract The novel ternary Zintl phase Li 3 NaGe 2 comprises alkali‐metal cations and [Ge 2 ] ... the unperturbed, ligand‐free dumbbell in Li 3 NaGe 2 , the π‐ bonding p y and p ... type bands of the neat solid Li 3 NaGe 2 cross the Fermi level, resulting in metallic properties. Li 3 NaGe 2 was synthesized from the elements as well ...
Tópico(s): Inorganic Chemistry and Materials
2015 - Wiley | Angewandte Chemie International Edition
Lavinia M. Scherf, Antti J. Karttunen, Oliver Pecher, Pieter C. M. M. Magusin, Clare P. Grey, Thomas F. Fässler,
Abstract The novel ternary Zintl phase Li 3 NaGe 2 comprises alkali‐metal cations and [Ge 2 ] ... the unperturbed, ligand‐free dumbbell in Li 3 NaGe 2 , the π‐ bonding p y and p ... type bands of the neat solid Li 3 NaGe 2 cross the Fermi level, resulting in metallic properties. Li 3 NaGe 2 was synthesized from the elements as well ...
Tópico(s): Inorganic Chemistry and Materials
2015 - Wiley | Angewandte Chemie
... the research methodology, probes into the use of nage (literally “that”) as a practice of managing awkward, ... and turn manipulation, the caller uses stand-alone nage, either as a pronoun referring to a sex ... sex organs or sex-related problems. In addition, nage also makes a compounded occurrence as “nage+noun.” Both in the stand-alone form and the compounded form, nage as a delicate issue managing practice in some ...
Tópico(s): Multilingual Education and Policy
2014 - Taylor & Francis | Discourse Processes
Jia‐Xi Zhou, Wang Jing-song, Dezhi Yang, Jinhai Liu,
Abstract: The Nage Cu‐Pb deposit, a new found ore deposit in the southeast Guizhou province, southwest China, is located on ... Massive and disseminated Cu‐Pb ores from the Nage deposit occur as either veinlets or disseminations in ... of ore‐forming fluids and metals for the Nage Cu‐Pb deposit. The δCu NBS values of ... geology, indicating that the ore genesis of the Nage Cu‐Pb deposit is post‐magmatic hydrothermal type.
Tópico(s): earthquake and tectonic studies
2013 - Wiley | Acta Geologica Sinica - English Edition
Laurent K. Blais, Francis Trilles,
... d’efficacite necessaires a l’execution de Seoi Nage. Au-dela d’une analyse empirique de cette ... de cette technique) dans l’execution de Seoi Nage sous forme de nage komi. Notre outil cinematographique (5 cameras videos a ... action fondamentaux (ou habiletes techniques fondamentales) de Seoi Nage.
Tópico(s): Martial Arts: Techniques, Psychology, and Education
2004 - EDP Sciences | Science & Motricité
North American ginseng (Panax quinquefolium) root extract (NAGE) with known ginsenosides composition was examined for its affinity to stimulate human tumour necrosis factor α (TNF-α) production in human peripheral blood ... mononuclear cells were incubated with varying concentrations of NAGE for up to 72 h and culture media ... mononuclear cell TNF-α production in vitro by NAGE occurred as early as 6 h with 200 μg NAGE/mL. The stimulation of TNF-α production was ... These interesting results show the immunostimulating activity of NAGE components in reference to TNF-α production. This ...
Tópico(s): Immune Cell Function and Interaction
2002 - NRC Research Press | Canadian Journal of Physiology and Pharmacology
Denise K. Hawkins, Thomas P. Quinn,
Nous avons calcule les vitesses critiques de nage pour deux stocks d'elevage de truite fardee (Oncorhynchus clarki clarki), un stock d'elevage de truite arc-en-ciel anadrome (Oncorhynchus mykiss) ... en-ciel anadrome presentait la vitesse critique de nage la plus elevee (7,69 longueurs corporelles/s), ... Conformement aux differences significatives dans la performance de nage, l'analyse des composantes principales a revele que ... poissons sauvages des resultats sur la performance de nage. Si les poissons sauvages etaient en general plus ...
Tópico(s): Fish Biology and Ecology Studies
1996 - Canadian Science Publishing | Canadian Journal of Fisheries and Aquatic Sciences
Jacqueline Plumbridge, Annie Kolb,
The divergent nagE-BACD operons located at 15.5 min on the Escherichia coli chromosome encode genes involved in the uptake ... investigate the binding of repressor to the intergenic nagE-B regulatory region. Two binding sites have been detected, overlapping the promoters of the nagE and nagB genes. NagC binding produces a series ... 61.5 and -71.5 relative to the nagE and nagB transcription start sites. CAP and NagC ...
Tópico(s): Bacteriophages and microbial interactions
1991 - Elsevier BV | Journal of Molecular Biology
... activité précoce se traduit par un comportement de nage contre le courant pour maintenir une position stable. Au début, ce comportement de nage statique est effectué en séquences brèves. Ensuite, les alevins exécutent des séquences de nage statique de plus en plus longues et de moins en moins nombreuses. Le comportement de nage statique précède le comportement territorial.
Tópico(s): Soil erosion and sediment transport
1978 - EDP Sciences | Annales de Limnologie - International Journal of Limnology
Tomoyuki Nakanishi, Masahito Hitosugi, Haruo Murayama, Arisa Takeda, Yasuki Motozawa, Masahiro Ogino, Katsuhiro Koyama,
... device (POLAR dummy) using three throwing techniques (Seoi-nage, Osoto-gari, and Ouchi-gari). The dummy’s ... and beam criterion were also calculated. In Seoi-nage, the anterior and parietal regions of the dummy’ ... injury scale score ≥2 were shown in Seoi-nage than in either Ouchi-gari or Osoto-gari. In judo, when thrown by the Seoi-nage technique, serious neck injuries can occur as a ...
Tópico(s): Traumatic Ocular and Foreign Body Injuries
2021 - Multidisciplinary Digital Publishing Institute | Healthcare
Caridad Rodríguez, Eugenio Hardy,
... LPS) aggregates separated by native agarose gel electrophoresis (NAGE). As a result, a new staining procedure was ... is applicable to two-dimensional LPS separation using NAGE/SDS-PAGE, while at the same time confirming ... of this stain to the detection of different NAGE-separated LPS aggregates (e.g., from E. coli ... double-staining process to enable the use of NAGE for investigating the interaction of cationic proteins and ...
Tópico(s): Advanced Biosensing Techniques and Applications
2015 - Elsevier BV | Analytical Biochemistry
Izumi Orita, Reiko Iwazawa, Satoshi Nakamura, Toshiaki Fukui,
... its upstream region identified a missense mutation in nagE corresponding to Gly265Arg in the EIIC-EIIB component, ... attributed to extended sugar specificity of the mutated NagE and derepression of nagFE expression by inactivation of NagR. The mutation in nagE and disruption of nagR were then introduced onto ... homologous recombination. The resulting engineered strain C. necator nagE_G265R∆nagR exhibited comparable growth and poly(3- ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2011 - Elsevier BV | Journal of Bioscience and Bioengineering