Nami Hattori, Tamaki Hayashi, Ken Nakachi, H. Ichikawa, Chiho Goto, Shinkan Tokudome, Kiyonori Kuriki, Hideki Hoshino, K. Shibata, N. Yamada, Mizuho Tokudome, Sadao Suzuki, Tsutomu Nagaya, Mariko Kobayashi, Shinkan Tokudome,
To assess oxidative stress (OS) induced by endurance exercise, concentrations of serum reactive oxygen species (ROS) were determined in 70 Japanese male amateur runners completing a two-day ultra-marathon race. Serum ROS levels were analyzed at three time points: before the race (baseline), after the 1st day race (mid-race), and after the 2nd day race (goal) (post-race). The means (SE) of ROS were 151.4(3.7) (U. CARR.), 168.7(4.4), and 156.8(4.4), respectively. Significant positive trends were noted between ...
Tópico(s): Sports Performance and Training
2009 - Thieme Medical Publishers (Germany) | International Journal of Sports Medicine
Keita Hara, Takuya Tanabe, Tomoki Aomatsu, Nao Inoue, Hirohumi Tamaki, Nami Okamoto, Keisuke Okasora, Takahiro Morimoto, Hiroshi Tamai,
To clarify the clinical impact of influenza A on the development of febrile seizures (FS), consecutive FS patients brought to our hospital between October 2003 and September 2004 were prospectively surveyed. Patients infected with influenza A (influenza A patients) and those uninfected with influenza (non-influenza patients) were compared with regard to clinical characteristics of FS. Influenza infection was determined by rapid antigen test and/or serologically. Associations of influenza A with atypical ...
Tópico(s): Influenza Virus Research Studies
2006 - Elsevier BV | Brain and Development
K. Tamaki, Nami Yasaka, Atsushi Osada, Naotaka Shibagaki, Masutaka Furue,
Journal Article Successful treatment of pigmented purpuric dermatosis with griseoiulvin Get access K. Tamaki, K. Tamaki Department of Dermatology, Yamanashi Medical University, 1110 Shimokato, Tamaho, Nakakoma, Yamanashi 409‐38, Japan Search for other works by this author on: Oxford Academic Google Scholar N. Yasaka, N. Yasaka Department of Dermatology, Yamanashi Medical University, 1110 Shimokato, Tamaho, Nakakoma, Yamanashi 409‐38, Japan Search for other works by this author on: Oxford Academic ...
Tópico(s): Eosinophilic Disorders and Syndromes
1995 - Oxford University Press | British Journal of Dermatology
Kunihiko Tamaki, Nami Yasaka, Chung‐Hsing Chang, Naoto OHTAKE, Atsushi Saitoh, Koichiro Nakamura, Masutaka Furue,
Using immunofluorescence on dermal sheets of mouse ear, we identified novel Thy-1+ dermal dendritic cells in murine skin. These cells are resistant to topical corticosteroid treatment. The number of these dermal Thy-1+ dendritic cells is not altered with aging of the mice or with 3 d of culture. Dermal Thy-1+ dendritic cells have melanosomes in their cytoplasm; hence, phagocytic activity is likely to be present. Double immunofluorescence revealed that most of these dermal Thy-1+ dendritic cells ...
Tópico(s): Dermatology and Skin Diseases
1996 - Elsevier BV | Journal of Investigative Dermatology
Kenji Wakai, Nobuyuki Hamajima, Rieko Okada, Mariko Naito, M. Emi, Asahi Hishida, Sayo Kawai, Kazuko Nishio, Guang Yin, Yatami Asai, Keitaro Matsuo, Satoyo Hosono, Hidemi Ito, Miki Watanabe, Takakazu Kawase, Takeshi Suzuki, Kazuo Tajima, Keitaro Tanaka, Yasuki Higaki, Megumi Hara, Takeshi Imaizumi, Naoto Taguchi, Kazuyo Nakamura, Hinako Nanri, Tatsuhiko Sakamoto, Mikako Horita, Koichi Shinchi, Yoshikuni Kita, Tanvir Chowdhury Turin, Nahid Rumana, Kenji Matsui, Katsuyuki Miura, Hirotsugu Ueshima, Naoyuki Takashima, Yasuyuki Nakamura, Sadao Suzuki, Ryosuke Ando, Akihiro Hosono, Nahomi Imaeda, Kiyoshi Shibata, Chiho Goto, Nami Hattori, Mitsuru Fukatsu, Tamaki Yamada, Shinkan Tokudome, Toshiro Takezaki, Hideshi Niimura, Kazuyo Hirasada, Akihiko Nakamura, Masaya Tatebo, Shin Ogawa, Noriko Tsunematsu, Shirabe Chiba, Haruo Mikami, Suminori Kono, Keizo Ohnaka, Ryoichi Takayanagi, Yoshiyuki Watanabe, Etsuko Ozaki, Masako Shigeta, Nagato Kuriyama, Aya Yoshikawa, Daisuke Matsui, Isao Watanabe, Kaoru Inoue, Kotaro Ozasa, Satoko Mitani, Kokichi Arisawa, Hirokazu Uemura, Mineyoshi Hiyoshi, Hidenobu Takami, Miwa Yamaguchi, Mariko Nakamoto, H. TAKEDA, Michiaki Kubo, Hideo Tanaka,
Background: Most diseases are thought to arise from interactions between environmental factors and the host genotype. To detect gene–environment interactions in the development of lifestyle-related diseases, and especially cancer, the Japan Multi-institutional Collaborative Cohort (J-MICC) Study was launched in 2005.Methods: We initiated a cross-sectional study to examine associations of genotypes with lifestyle and clinical factors, as assessed by questionnaires and medical examinations. The 4519 ...
Tópico(s): Genetic Associations and Epidemiology
2011 - Japan Epidemiological Association | Journal of Epidemiology
Nami Yasaka, Masutaka Furue, Kunihiko Tamaki,
Cutaneous lymphocyte-associated antigen (CLA) defined by monoclonal antibody (MoAb) HECA-452 has been shown to be preferentially expressed on cutaneous T cells. The CLA expression has been regarded as a homing molecule of T cells to the skin in various inflammatory cutaneous disorders. In this paper we investigated the significance of CLA expression on Langerhans cells (LC) and found that, in normal skin, some epidermal LC express CLA, and that most dermal CD1a positive cells express CLA. When normal ...
Tópico(s): Autoimmune Bullous Skin Diseases
1996 - Elsevier BV | Journal of Dermatological Science
Nami Yasaka, Masutaka Fume, Kunihiko Tamaki,
We saw a patient with a Spitz nevus surrounded by a halo of depigmentation. Although the halo phenomenon is often seen in pigmented melanocytic nevus, an association of this phenomenon with Spitz nevus seems to be rare. Moreover, histopathological findings showed focal lym-phoid infiltration in the epidermis of the depigmented halo and marked infiltration in dermal epithelioid nevus cell nests. Thus, it is suggested that identical mechanisms are involved in the destruction of epidermal melanocytes ...
Tópico(s): Cutaneous Melanoma Detection and Management
1995 - Lippincott Williams & Wilkins | American Journal of Dermatopathology
Nami Yasaka, Masutaka Furue, Kunihiko Tamaki,
Abstract CD44 is thought to be a principal cell surface receptor for hyaluronic acid. Although the distribution of hyalulonic acid has been studied, little is known about the distribution of the CD44 molecule in the human skin and skin tumors. This study was undertaken to investigate the distribution of the CD44 molecule in normal human skin as well as in benign and malignant skin tumors. In normal skin, CD44 was expressed on 1) keratinocyte cell surfaces throughout the epidermis except for the ...
Tópico(s): Fibroblast Growth Factor Research
1995 - Wiley | The Journal of Dermatology
Yuzuru Nagaoka, Koichiro Nakamura, Takahiro Watanabe, Akihiko Asahina, Kunihiko Tamaki, Nami Yasaka,
CD23 is a low-affinity receptor for immunoglobulin E and expressed on various hemopoietic cells. Although human epidermal cultured Langerhans cells express CD23, the study to identify CD23 on murine Langerhans cells has so far failed. In this study, using highly enriched (> 95%) Langerhans cells from murine epidermis obtained by the panning method, we investigated whether murine Langerhans cells express CD23. As the result of a series of experiments using fluorescence activated cell sorter analysis ...
Tópico(s): Cell Adhesion Molecules Research
2002 - Elsevier BV | Journal of Investigative Dermatology
Chihiro Akiyama, Atsushi Osada, K Sou, Nami Yasaka, Naoto OHTAKE, Masutaka Furue, K. Tamaki,
No Abstract available
Tópico(s): Genetic Syndromes and Imprinting
1997 - Soc for Publication of Acta Dermato-Venereologica | Acta Dermato Venereologica
K. Tamaki, Atsushi Saitoh, Nami Yasaka,
Journal Article Differential effect of griseofulvin on interferon‐γ‐induced HLA‐DR and intercellular adhesion molecule‐1 expression of human keratinocytes Get access K. TAMAKI, K. TAMAKI Department of Dermatology, Yamanashi Medical College, 1110 Shimokatoh, Tamaho‐cho, Nakakoma‐gun, Yamanashi‐ken 409‐38, Japan Dr K. Tamaki. Search for other works by this author on: Oxford Academic Google Scholar A. SAITOH, A. SAITOH Department of Dermatology, Yamanashi Medical College, 1110 Shimokatoh, Tamaho‐cho, ...
Tópico(s): Mycotoxins in Agriculture and Food
1992 - Oxford University Press | British Journal of Dermatology
Chie Akiyama, K Sou, T Furuya, Atsushi Saitoh, Nami Yasaka, Naoto OHTAKE, Yasuo Kubota, Shinji Shimada, Kunihiko Tamaki,
Tópico(s): Skin Diseases and Diabetes
1993 - Elsevier BV | Journal of the American Academy of Dermatology
Naoyuki Iwahashi, Yoko Deguchi, Yuko Horiuchi, Tomoko Noguchi, Tamaki Yahata, Nami Ota, Kazuhiko Ino, Ken‐Ichi Furukawa,
Papillary thyroid carcinoma arising from ovarian mature cystic teratoma is clinically rare. We herein present a case of live birth following two laparoscopic surgeries for papillary thyroid carcinoma arising in a mature ovarian cystic teratoma. A 30‑year‑old female patient, gravida 1 para 1, was treated by laparoscopic bilateral ovarian cystectomy for suspicion of bilateral mature cystic teratoma. The diagnosis of papillary thyroid carcinoma arising from right ovarian mature cystic teratoma was ...
Tópico(s): Ovarian function and disorders
2018 - Spandidos Publishing | Molecular and Clinical Oncology
Koichiro Nakamura, Nami Yasaka, Akihiko Asahina, Mitsuyasu Kato, Kohei Miyazono, Masutaka Furue, Kunihiko Tamaki,
CD68 is a myelomonocytic marker identified in human dermal macrophages. Although the existence of CD68 + dendritic epidermal cells has been reported, their characteristics have not been well elucidated. Cutaneous lymphocyte-associated antigen (CLA) is a homing receptor of cutaneous inflammatory T cells. Our recent report suggested that CLA was a homing molecule of CD1a+ Langerhans cells (LC) in the skin. In the present study we tested whether CD68 and CLA+ dendritic epidermal cells were present in skin ...
Tópico(s): T-cell and B-cell Immunology
1998 - Elsevier BV | Journal of Dermatological Science
Nobuharu Tamaki, Masayuki Kurosaki, Yutaka Yasui, Nami Mori, Keiji Tsuji, Chitomi Hasebe, Koji Joko, Takehiro Akahane, Koichiro Furuta, Haruhiko Kobashi, Hiroyuki Kimura, Hitoshi Yagisawa, Hiroyuki Marusawa, Masahiko Kondo, Yuji Kojima, Hideo Yoshida, Yasushi Uchida, Rohit Loomba, Namiki Izumi,
Abstract Background It is unclear whether the fibrosis 4 index (FIB-4), a marker of liver fibrosis, at baseline and change in FIB-4 after sustained virological response (SVR) is associated with incident hepatocellular carcinoma (HCC) risk. In this study, we examined the association of incident HCC risk with baseline FIB-4 and sustained high FIB-4 (>3.25) at any time point after SVR. Methods A total of 3823 patients who received direct-acting antiviral treatment and achieved SVR were enrolled. The ...
Tópico(s): Hepatitis B Virus Studies
2020 - Oxford University Press | Clinical Infectious Diseases
Kumiko Nakata, Naoyuki Iwahashi, Hitomi Matsukawa, Tomoko Noguchi, Tamaki Yahata, Nami Ota, Yasushi Mabuchi, Kazuhiko Ino,
Castleman's disease is a rare benign disorder of unknown etiology characterized by proliferation of lymphoid tissues. Castleman's disease arising from pelvic retroperitoneum is clinically rare. The present case report describes a rare case of laparoscopically resected Castleman's disease in the pelvic retroperitoneum associated with benign ovarian cyst. A 47-year-old woman, gravida 5, para 3, was referred to to the Department of Obstetrics and Gynecology of Wakayama Medical University with a suspected ...
Tópico(s): Ovarian cancer diagnosis and treatment
2019 - Spandidos Publishing | Molecular and Clinical Oncology
Koichiro Nakamura, Kunihiko Tamaki, Atsushi Saitoh, Nami Yasaka, Masutaka Furue,
The murine epidermis contains two types of dendritic cells (DC), Thy-1+ dendritic epidermal T cells (DETC) and Langerhans cells. In this review, we introduce our data obtained using a skin organ culture system to examine the migratory capacity of DETC and Langerhans cells into the epidermis. DETC or Langerhans cells were depleted by topical application ofclobetazole propionate (CP) solution onto the murine ears. CP-treated or untreated ear skin was co-cultured with syngeneic (semi-syngeneic, or allogenic, ...
Tópico(s): NF-κB Signaling Pathways
1999 - Elsevier BV | Journal of Investigative Dermatology Symposium Proceedings
Yasushi Mabuchi, Tamaki Yahata, Aya Kobayashi, Yuko Tanizaki, Michihisa Shiro, Nami Ota, Shigetaka Yagi, Sawako Minami, Kazuhiko Ino,
The aim of this study was to clarify the clinicopathologic factors of stages IB to IIB cervical adenocarcinoma.Several clinicopathologic factors were compared between 35 patients who underwent radical hysterectomy and pelvic lymphadenectomy due to cervical adenocarcinoma stages IB to IIB and 77 patients with squamous cell carcinoma (SCC).In patients with adenocarcinoma, univariate analysis demonstrated that International Federation of Gynecology and Obstetrics stage, tumor size, and lymphovascular ...
Tópico(s): Colorectal and Anal Carcinomas
2015 - BMJ | International Journal of Gynecological Cancer
Nami Yasaka, Ken Iozumi, Kiyoko Nashiro, Tetsuya Tsuchida, Yoshihito Seki, Masutaka Furue, Osami Takayama, Shinji Shimada, Kunihiko Tamaki,
Abstract We saw four patients showing identical features as cystic lesions on the bilateral external canthi. Histological examination showed cystic cavities in the dermis. Histological and enzyme histochemical findings suggest that these cystic tumors are of eccrine origin. Thus we diagnosed these cytic tumors as eccrine hidrocystoma with characteristic clinical feature. The recognition of this feature would help to correctly diagnose these eccrine hidrocystoma.
Tópico(s): Hedgehog Signaling Pathway Studies
1994 - Wiley | The Journal of Dermatology
Toshifumi Tada, Masayuki Kurosaki, Nobuharu Tamaki, Yutaka Yasui, Nami Mori, Keiji Tsuji, Chitomi Hasebe, Koji Joko, Takehiro Akahane, Koichiro Furuta, Haruhiko Kobashi, Hiroyuki Kimura, Hitoshi Yagisawa, Hiroyuki Marusawa, Masahiko Kondo, Yuji Kojima, Hideo Yoshida, Yasushi Uchida, Shinichiro Nakamura, Namiki Izumi,
The pathogenic process underlying the development of hepatocellular carcinoma (HCC) is not yet clear in patients with hepatitis C virus (HCV) who have received direct-acting antiviral (DAA) therapy and achieved sustained virological response (SVR). This study validated a composite predictive model for HCC in these patients.This study included 3058 patients in whom HCV was eradicated with DAA therapy. After DAAs recommendation for surveillance (ADRES) score, which is based on sex, FIB-4 index, and α-fetoprotein, ...
Tópico(s): Hepatitis B Virus Studies
2021 - Wiley | JGH Open
Nobuharu Tamaki, Masayuki Kurosaki, Yutaka Yasui, Nami Mori, Keiji Tsuji, Chitomi Hasebe, Kouji Joko, Takehiro Akahane, Koichiro Furuta, Haruhiko Kobashi, Hiroyuki Kimura, Hitoshi Yagisawa, Hiroyuki Marusawa, Masahiko Kondo, Yuji Kojima, Hideo Yoshida, Yasushi Uchida, Toshifumi Tada, Shinichiro Nakamura, Satoshi Yasuda, Hidenori Toyoda, Rohit Loomba, Namiki Izumi,
The identification of patients with advanced fibrosis who do not need any further hepatocellular carcinoma (HCC) surveillance after the eradication of hepatitis C is pivotal. In this study, we developed a simple serum‐based risk model that could identify patients with low‐risk HCC. This was a nationwide multicenter study involving 16 Hospitals in Japan. Patients with advanced fibrosis (1,325 in a derivation cohort and 508 in a validation cohort) who achieved sustained virological responses at 24 weeks ...
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
2021 - Lippincott Williams & Wilkins | Hepatology Communications
Nami Sawada, Tamaki Morohashi, Tomokazu Mutoh, Tsukasa Kuwana, Junko Yamaguchi, Kosaku Kinoshita, Ichiro Morioka, Hiroyuki Hao,
Abstract Moraxella lacunata ( M. lacunata ) is a Gram-negative bacterium, which rarely causes serious infection. This is a rare case report of acute glomerulonephritis diagnosed by pathological findings in a child accompanied by M. lacunata infection. The patient showed hematuria, proteinuria and hyperkalemia requiring emergency hemodialysis. After hospitalization, M. lacunata bacteremia became apparent. Pathological findings showed an increase in glomerulus inflammatory cells and glomerular C3 deposition ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2020 - De Gruyter Open | Open Medicine
Kunihiko Tamaki, Atsushi Saitoh, Anthony A. Gaspari, Nami Yasaka, Masutaka Furue,
Tópico(s): Cell Adhesion Molecules Research
1994 - Elsevier BV | Journal of Investigative Dermatology
Makoto Sugaya, Koichiro Nakamura, Takahiro Watanabe, Akihiko Asahina, Nami Yasaka, Yoh‐ichi Koyama, Masashi Kusubata, Yuko K. Ushiki, Kumiko KIMURA, Akira Morooka, Shinkichi Irie, Takashi Yokoyama, Keiichi Inoue, Shigeyosi Itohara, Kunihiko Tamaki,
Transmissible spongiform encephalopathies are characterized by the accumulation of a proteinase-resistant isoform of the cellular prion-related protein (PrP(c)) within the central nervous system (CNS). The accumulation of scrapie-associated PrP (PrP(Sc)) within cells of the lymphoreticular system prior to its accumulation in the CNS is regarded as important for the development of neurological diseases after peripheral inoculation. Little, however, is known as to which cells are the targets for peripheral ...
Tópico(s): Neurological diseases and metabolism
2002 - Elsevier BV | Journal of Dermatological Science
Nami Yasaka, N Otake, Masutaka Furue, K. Tamaki,
We report a 50-year-old Japanese woman with a 3-year history of systemic lupus erythematosus treated with prednisolone, who had diffuse plane yellowish macules mainly on the upper arm. The lesion was clinically diagnosed as diffuse plane xanthomatosis. However, the histopathological findings from both the yellowish macules and the normal-appearing skin revealed a heavy degeneration of collagen fibers with membranocystic structure throughout the entire dermis and the collagenous septum of the subcutaneous ...
Tópico(s): Nuclear Structure and Function
1997 - Karger Publishers | Dermatology
Nami Yasaka, Kenichi Kawabe, Masutaka Furue, K Tamaki, Y. Ishibashi,
Tópico(s): Cancer and Skin Lesions
1994 - Elsevier BV | Journal of Dermatological Science
Nami Mori, Nobuharu Tamaki, Shintaro Takaki, Keiji Tsuji, Toshifumi Tada, Shinichiro Nakamura, Hironori Ochi, Toshie Mashiba, Masao Doisaki, Hiroyuki Marusawa, Haruhiko Kobashi, Hideki Fujii, Chikara Ogawa, Michiko Nonogi, Hirotaka Arai, Yasushi Uchida, Naohito Urawa, Ryoichi Narita, Takehiro Akahane, Masahiko Kondo, Yutaka Yasui, Kaoru Tsuchiya, Namiki Izumi, Masayuki Kurosaki,
Tópico(s): Liver Disease Diagnosis and Treatment
2024 - Springer Science+Business Media | Investigational New Drugs
Yasushi Mabuchi, Yoshihiro Takiguchi, Tamaki Yahata, Mika Mizoguchi, Noriyuki Sasaki, Nami Ota, Sawako Minami, Kazuhiko Ino,
The aim of the present study was to clarify the feasibility and efficacy of helical tomotherapy during concurrent chemoradiotherapy for treating cervical cancer. The medical records of 13 patients who underwent oncurrent chemoradiotherapy using helical tomotherapy for cervical cancer at Wakayama Medical University Hospital between 2013 and 2015 were retrospectively reviewed. A total of 15 patients who underwent oncurrent chemoradiotherapy using conventional radiotherapy (CRT) between 2008 and 2013 ...
Tópico(s): Management of metastatic bone disease
2019 - Spandidos Publishing | Molecular and Clinical Oncology
Nami Yasaka, Mayumi Fujimoto, Kunihiko Tamaki,
... for more papers by this authorKunihiko Tamaki, Kunihiko Tamaki Department of Dermatology, Yamanashi Medical College, Yamanashi-ken, JapanSearch for more papers by this author Nami Yasaka, Corresponding Author Nami Yasaka Department of Dermatology, Yamanashi Medical College, Yamanashi-ken, JapanReprint requests to: Nami Yasaka, M.D., Department of Dermatology, Yamanashi Medical College, 1110 Shimokatoh, Tamaho-cho, Nakakoma-gun, Yamanashi-ken 409-38, Japan.Search for more papers by this authorMayumi Fujimoto, Mayumi Fujimoto Department of Dermatology, Yamanashi Medical College, Yamanashi-ken, JapanSearch for more papers by this authorKunihiko Tamaki, Kunihiko Tamaki Department of Dermatology, Yamanashi Medical College, ...
Tópico(s): Dermatological and Skeletal Disorders
1992 - Wiley | The Journal of Dermatology
Chihiro Akiyama, Naotaka Shibagaki, Nami Yasaka, Naoto OHTAKE, Y. Kuhota, Osamu Takayama, Ryohei Katoh, Shinji Shimada, Masutaka Furue, K. Tamaki,
A 71-year-old Japanese woman had two dome-shaped tumors on her right buttock with several surrounding papules. Histological examination revealed that large anaplastic cells and atypical lymphoid cells densely infiltrated the entire dermis. On immunohistochemical examination, Ki-1, HLA-DR, CD25 (IL-2 receptor alpha), CD122 (IL-2 receptor beta), CD4, CD11c and CD68 were all positive in the tumor cells, whereas CD1a, CD3, CD5, CD8 and CD19 were negative. Neither rearrangement of the T-cell receptor beta, ...
Tópico(s): Fungal Infections and Studies
1995 - Karger Publishers | Dermatology