Produção Nacional
Revisado por pares
Victor Aquino Wanderley, Frederico Sampaio Neves, Monikelly do Carmo Chagas Nascimento, Gabriela Queiroz de Melo Monteiro, Natália Siqueira Lobo, Matheus Lima Oliveira, Joao Batista Sobrinho Nascimento Neto, Luciane Farias de Araújo,
The purpose of this study was to compare different high-resolution cone-beam computed tomographic (CBCT) imaging protocols in the diagnosis of incomplete root fractures of endodontically treated teeth.Twenty single-rooted human teeth were endodontically treated, and an incomplete root fracture was induced. The teeth were scanned with the CBCT unit PreXion 3D (Teracom, San Mateo, CA) operating at 2 different protocols: high resolution/standard (HI-STD) (19 seconds and 512 basis images) and high resolution/ ...
Tópico(s): Advanced X-ray and CT Imaging
2017 - Elsevier BV | Journal of Endodontics
Produção Nacional
Revisado por pares
Ana Eloísa Cruz de Oliveira, Isis Milane Batista de Lima, João Agnaldo do Nascimento, Hemílio Fernandes Campos Coêlho, Sérgio Ribeiro dos Santos,
RESUMO Os sistemas de informação têm o propósito de auxiliar os gestores nas tomadas de decisões. O e-SUS AB facilita e contribui para a organização do trabalho dos profissionais de saúde na Atenção Básica. O presente artigo tem o objetivo de apresentar o processo de implantação e desenvolvimento do e-SUS AB no Distrito Sanitário IV de João Pessoa (PB), em 2014. Trata-se de um estudo descritivo, na forma de relato de experiência, o qual aponta as dificuldades e qualidades do sistema. Conclui-se que ...
Tópico(s): Health Education and Validation
2016 - Centro Brasileiro de Estudos de Saúde | Saúde em Debate
Produção Nacional
Revisado por pares
Joana Filomena Magalhães Leite, Ana Maria Sampaio Assreuy, Mário Rogério Lima Mota, Pedro Henrique de Souza Ferreira Bringel, Rodrigo Rodrigues e‐Lacerda, Vinícius M. Gomes, João Batista Cajazeiras, Kyria Santiago Nascimento, Hilzeth de Luna Freire Pessôa, Carlos Alberto de Almeida Gadelha, P. Delatorre, Benildo Sousa Cavada, Tatiane Santi‐Gadelha,
Lectins are proteins that have the ability to bind specifically and reversibly to carbohydrates and glycoconjugates, without altering the structure of the glycosyl ligand. They are found in organisms such as viruses, plants and humans, and they have been shown to possess important biological activities. The objective of this study was to purify and characterize lectins in the seeds of Clitoria fairchildiana, as well as to verify their biological activities. The results indicated the presence of ...
Tópico(s): Essential Oils and Antimicrobial Activity
2012 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Francisco Cleiton Ribeiro Freitas, Nilberto Robson Falcão do Nascimento, João Batista Gadelha de Cerqueira, Michele Morais, Rommel Prata Regadas, Lúcio Flávio Gonzaga-Silva,
Tópico(s): Pain Mechanisms and Treatments
2009 - Springer Nature | International Journal of Impotence Research
Produção Nacional
Revisado por pares
Letícia Serpa Sampaio Moreno, Hélio Vitoriano Nobre Júnior, Anderson Ramos da Silva, Francisca Bruna Stefany Aires do Nascimento, Cecília Rocha da Silva, João Batista de Andrade Neto, Bruno C. Cavalcanti, Manoel Odorico de Moraes, Aurora Pinazo, Lourdes Pérez,
Tópico(s): Antifungal resistance and susceptibility
2021 - Elsevier BV | Colloids and Surfaces B Biointerfaces
Produção Nacional
Revisado por pares
Anderson Ramos da Silva, Hélio Vitoriano Nobre Júnior, Sandro Serpa, Francisca Bruna Stefany Aires do Nascimento, Cecília Rocha da Silva, João Batista de Andrade Neto, Ángeles Manresa, Aurora Pinazo, Bruno C. Cavalcanti, Manoel Odorico de Moraes, Iñaki Ruiz‐Trillo, Meritxell Antó, M. Carmen Morán, Lourdes Pérez,
Nowadays, infections caused by fungi and protists constitute a serious problem for public health services. The limited number of treatment options coupled with the increasing number of resistant microorganisms makes necessary the development of new non-toxic antifungal and antiprotozoal agents. Cationic amino acid-based rhamnolipids have been recently prepared by our group and exhibited good antibacterial activity. In this work, the antifungal, antibiofilm and antiprotozoal activity of these new ...
Tópico(s): Legionella and Acanthamoeba research
2020 - Elsevier BV | Colloids and Surfaces B Biointerfaces
Produção Nacional
Revisado por pares
Paula Cristina Batista de Faria, Angela Aparecida Servino Sena, Rafael Nascimento, Washington João Carvalho, Adriano Mota Loyola, Sindeval José Silva, Antônio Francisco Durighetto, Amanda Ribeiro de Oliveira, Sônia Maria Oliani, Luíz Ricardo Goulart,
Several studies have been suggesting annexin A1 protein as an active player in tumorigenesis of many organs. Nevertheless, its tumor biomarker role has been mainly studied in tissues by immunohistochemistry or cell culture. Hence, in this investigation, the peripheral blood from 27 oral squamous cell carcinoma (OSCC) patients and 25 negative control individuals were examined by quantitative real-time PCR. Down-regulated ANXA1 expression at mRNA level was observed in OSCC samples (p = 0.026). Significantly ...
Tópico(s): Biomarkers in Disease Mechanisms
2009 - Elsevier BV | Oral Oncology
Produção Nacional
Revisado por pares
Cristina W. Nogueira, Félix Alexandre Antunes Soares, Paulo Cı́cero do Nascimento, Daniel Curvello de Mendonça Müller, João Batista Teixeira da Rocha,
Compounds derived from Dimercaprol, such as meso-2,3-dimercaptosuccinic acid (DMSA) and 2,3-dimercaptopropane-1-sulfonic acid (DMPS), are becoming common agents for treating humans exposed to heavy metals. Heavy metals such as Pb(2+), Hg(2+) and Cd(2+) can inhibit delta-aminolevulinate dehydratase (delta-ALA-D) activity. Delta-ALA-D catalyzes the condensation of two delta-aminolevulinic acid (delta-ALA) molecules with the formation of porphobilinogen, a heme precursor. The effects of DMSA and DMPS alone ...
Tópico(s): Neonatal Health and Biochemistry
2002 - Elsevier BV | Toxicology
Produção Nacional
Revisado por pares
Lívia Gurgel do Amaral Valente Sá, Cecília Rocha da Silva, João Batista de Andrade Neto, Francisca Bruna Stefany Aires do Nascimento, Fátima Daiana Dias Barroso, Lisandra Juvêncio da Silva, Vitória Pessoa de Farias Cabral, Amanda Dias Barbosa, Jacilene Silva, Emmanuel Silva Marinho, Manoel Odorico de Moraes, Maria Erivanda França Rios, Bruno C. Cavalcanti, Iri Sandro Pampolha Lima, Hélio Vitoriano Nobre Júnior,
This study evaluated the effect of etomidate against biofilms of Candida spp. and analysed through molecular docking the interaction of this drug with ALS3, an important protein for fungal adhesion. Three fluconazole-resistant fungi were used: Candida albicans, Candida parapsilosis and Candida tropicalis. Growing biofilms were exposed to etomidate at 31.25-500 µg ml-1. Then, an ALS3 adhesive protein from C. albicans was analysed through a molecular mapping technique, composed of a sequence of algorithms ...
Tópico(s): Fungal Infections and Studies
2020 - Microbiology Society | Journal of Medical Microbiology
Produção Nacional
Revisado por pares
P. Delatorre, B.A.M. Rocha, C.A.A. Gadelha, Tatiane Santi‐Gadelha, João Batista Cajazeiras, Emmanuel Prata de Souza, Kyria Santiago Nascimento, V. N. Freire, Alexandre Holanda Sampaio, Walter Filgueira de Azevedo, Benildo Sousa Cavada,
Tópico(s): Galectins and Cancer Biology
2006 - Elsevier BV | Journal of Structural Biology
Produção Nacional
Revisado por pares
João Manoel Miranda Magalhães Santos, Brunna Clemente Oliveira, José de Arimateia Batista Araújo-Filho, Antonildes Nascimento Assunção-Jr, Felipe Augusto de M. Machado, Camila Carlos Tavares Rocha, João V. Horvat, Marcos Roberto de Menezes, Natally Horvat,
Tópico(s): Renal cell carcinoma treatment
2019 - Springer Nature | Abdominal Radiology
Produção Nacional
Revisado por pares
Antônia Sâmia Fernandes do Nascimento, Ana C. S. Gondim, João Batista Cajazeiras, Jorge Luís Almeida Correia, Alana de Freitas Pires, Kyria Santiago Nascimento, André Luis C. da Silva, Celso Shiniti Nagano, Ana Maria Sampaio Assreuy, Benildo Sousa Cavada,
A lectin from seeds of Dioclea lasiocarpa (DLL) was purified in a single step by affinity chromatography in a Sephadex G‐50 column. DLL haemagglutinated rabbit erythrocytes showing stability even after 1 h of exposure to a different pH values (optimal between pH 6.0 and 8.0) but was inhibited after incubation with d ‐mannose and d ‐glucose. The pure protein possessed a molecular weight of 25 kDa by sodium dodecyl sulfate polyacrylamide gel electrophoresis and 25,410Da by mass spectrometry. The results ...
Tópico(s): Lysosomal Storage Disorders Research
2012 - Wiley | Journal of Molecular Recognition
Produção Nacional
Gilmar da Silva Nunes, Thaís Aparecida Vitoriano Dantas, Wennia Rafaely Souza Figueiredo, MARCELLA STHEFÂNIA CAFÉ DE SOUZA, Izabela Nunes do Nascimento, João Luı́s Ferreira Batista,
Diamondback moth, Plutella xylostella, is considered the most important pest species of brassica crops and Euborellia annulipes can exhibit potential for its control. This work recorded the consumption of 4th-instar larvae and pupae of P. xylostella by nymphs and adult females of the ring-legged earwig E. annulipes at different ages: 2, 4, 6, 8 and 10 days old. Nymphs in the 3rd-instar and females of E. annulipes consumed daily more P. xylostella larvae than pupae. The consumption of diamondback ...
Tópico(s): Insect Pest Control Strategies
2018 - UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO | Revista Brasileira de Ciências Agrárias - Brazilian Journal of Agricultural Sciences
Produção Nacional
Revisado por pares
Kifayat Ullah Khan, Andressa Tellechea Rodrigues, Cleber Menegasso Mansano, Daniel de Almeida, Nilva Kazue Sakomura, Rafael de Souza Romaneli, Thiago Torres do Nascimento, João Batista Kochenborger Fernandes,
Supplementing high levels of dietary crude protein in the absence of amino acid balance and enough energy in fish diets may results in reduced growth, improper feed intake and poor protein utilization efficiency coupled with unviable feed costs and adverse environmental effects due to high nitrogen excretion. It is necessary to improve the dietary protein quality to avoid unnecessary nitrogen excretion, and the use of protein as an energy source by fish, quality and determine proper dietary protein ...
Tópico(s): Aquaculture disease management and microbiota
2019 - Escuela de Ciencias del Mar, Facultad de Recursos Naturales, Pontificia Universidad Católica de Valparaíso | Latin American Journal of Aquatic Research
Produção Nacional
Nadège Bouchonneau, Adauto R. de Carvalho, Antonio Roberto L. de Macedo, Lílian U. Viana, Adriana P. do Nascimento, João Batista Furlan Duarte, Antônio Roberto Menescal de Macêdo,
Polímeros expandidos são bastante competitivos para serem utilizados como materiais de flutuabilidade, devido a sua baixa densidade. Em particular, eles se apresentam muito eficientes no desenvolvimento de módulos de flutuabilidade de robôs submarinos do tipo ROV (Remote Operated Vehicle). Este trabalho descreve um estudo da absorção de água em dois diferentes tipos de polímeros expandidos (poliuretano e poliestireno expandido), em diferentes meios aquosos (água do mar e água destilada). Estudo sobre ...
Tópico(s): Tribology and Wear Analysis
2010 - Associação Brasileira de Polímeros | Polímeros
Produção Nacional
Revisado por pares
Guilherme Augusto Foizer, Vagner Clayton de Paiva, Rodrigo Domingues do Nascimento, Carlos Górios, Alberto Cliquet, João Batista de Miranda,
Objective To access the possibility that higher degrees of disc degeneration lead to higher levels of pain and dysfunction. Methods Magnetic resonance imaging (MRI) scans of 85 patients with low back pain lasting for more than 12 weeks were evaluated, and the degree of disc degeneration was quantified according to the Pfirrmann grading system. The Pfirrmann degree in each disc space from L1-L2 to L5-S1, the maximum degree of Pfirrmann (Pfirrmann-max) between the lumbar discs, and the sum of Pfirrmann ( ...
Tópico(s): Pregnancy-related medical research
2021 - Thieme Medical Publishers (Germany) | Revista Brasileira de Ortopedia
Produção Nacional
Revisado por pares
Radigya M. Correia, Renato Nunes de Andrade, Flávia Tosato, Mariana T. Nascimento, Lucas Louzada Pereira, João Batista Silva Araújo, Fernanda E. Pinto, Denise Coutinho Endringer, Maria da Penha Padovan, Eustáquio Vinícius Ribeiro de Castro, Fábio Luiz Partelli, Paulo R. Filgueiras, Valdemar Lacerda, Wanderson Romão,
Abstract Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI(±)FT-ICR MS) and portable micro near-infrared spectroscopy (microNIR), coupled to sensory analysis, were used to propose a new analytical methodology to observe the characteristics of Robusta coffees cultivated in agroforestry systems (AFS). Principal component analysis (PCA) chemometric models provided excellent discrimination of the samples analyzed by ESI(±)FT-ICR mass spectra for the ground coffee grains. ...
Tópico(s): Meat and Animal Product Quality
2020 - Elsevier BV | Journal of Food Composition and Analysis
Produção Nacional
Revisado por pares
Jorge Luís Almeida Correia, Antônia Sâmia Fernandes do Nascimento, João Batista Cajazeiras, Ana C. S. Gondim, Ronniery Ilário Pereira, Bruno Lopes de Sousa, André Luiz Coelho da Silva, Wanius García, Edson Holanda Teixeira, Kyria Santiago Nascimento, B.A.M. Rocha, Celso Shiniti Nagano, Alexandre Holanda Sampaio, Benildo Sousa Cavada,
Lectin from the seeds of Dioclea sclerocarpa (DSL) was purified in a single step by affinity chromatography on a Sephadex G-50 column. The primary sequence, as determined by tandem mass spectrometry, revealed a protein with 237 amino acids and 81% of identity with ConA. DSL has a molecular mass of 25,606 Da. The β and γ chains weigh 12,873 Da and 12,752 Da, respectively. DSL hemagglutinated rabbit erythrocytes (both native and treated with proteolytic enzymes), showing stability even after one hour ...
Tópico(s): Transgenic Plants and Applications
2011 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Cassiano Francisco Weege Nonaka, Alexandre Pinto Maia, George João Ferreira do Nascimento, Roseana de Almeida Freitas, Lélia Batista de Souza, Hébel Cavalcanti Galvão,
Our aim was to assess and compare the immunoexpression of vascular endothelial growth factor (VEGF) in periapical granulomas (PGs), radicular cysts (RCs), and residual radicular cysts (RRCs), relating it to the angiogenic index and the intensity of the inflammatory infiltrate.Twenty PGs, 20 RCs, and 10 RRCs were evaluated by immunohistochemistry using anti-VEGF antibody. Angiogenic index was determined by microvessel count (MVC) using anti-von Willebrand factor antibody.The PGs and RCs showed higher ...
Tópico(s): Bone Tumor Diagnosis and Treatments
2008 - Elsevier BV | Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
Produção Nacional
Revisado por pares
Jefferson Costa de Siqueira, Nilva Kazue Sakomura, DÊNISSON DAVID GOMES DO NASCIMENTO, João Batista Kochenborger Fernandes,
O objetivo neste estudo foi avaliar diferentes modelos ajustados às respostas de ganho de peso obtidas em experimento com aves da linhagem ISA Label no período de 1 a 28 dias de idade. Foram utilizados 480 pintos de ambos os sexos, distribuídos em delineamento inteiramente casualizado, em arranjo fatorial 4 X 2 (níveis de lisina X sexo), com três repetições, com 20 aves por unidade experimental. Uma ração basal foi formulada para atender às exigências das aves, exceto em lisina. Essa ração foi suplementada ...
Tópico(s): Economic and Environmental Valuation
2009 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia
Produção Nacional
Revisado por pares
David F. N. Oliveira, Lúcio F. Vismari, Alexandre Nascimento, Jorge Rady de Almeida, Paulo Sérgio Cugnasca, João Batista Camargo, Leandro P. F. de Almeida, Rafael Gripp, Marcelo A. S. Neves,
Despite the superior performance in modeling complex patterns to address challenging problems, the black-box nature of Deep Learning (DL) methods impose limitations to their application in real-world critical domains. The lack of a smooth manner for enabling human reasoning about the black-box decisions hinder any preventive action to unexpected events, in which may lead to catastrophic consequences. To tackle the unclearness from black-box models, interpretability became a fundamental requirement ...
Tópico(s): Adversarial Robustness in Machine Learning
2021 - Institute of Electrical and Electronics Engineers | IEEE Access
Produção Nacional
Revisado por pares
Raniel Lustosa de Moura, Maria do Perpétuo Socorro C. B. Nascimento, Marcônio Martins Rodrigues, Maria Elizabete de Oliveira, João Batista Lopes,
The aim of this research study was to evaluate the bromatological composition and leaf-to-stem ratio of Campo-Grande stylo, at five regrowth ages, with and without phosphorus. The investigation was carried out in a randomized blocks experimental design, with four replications in a 2 x 5 factorial arrangement – two levels of phosphorus (with or without) and five cutting ages (30, 35, 40, 45 and 50 days). Phosphorus was applied as a single superphosphate, equivalent to 50 kg ha-1 P2O5. The leaf-to-stem ...
Tópico(s): Soil Management and Crop Yield
2011 - Editora da Universidade Estadual de Maringá (Eduem) | Acta Scientiarum Animal Sciences
Produção Nacional
Revisado por pares
Vanir Reis Pinto‐Junior, Mayara De Santiago, Vinicius José Silva Osterne, J. Pinto Correia, Francisco N. Pereira‐Junior, João Batista Cajazeiras, Mayron Alves de Vasconcelos, Edson Holanda Teixeira, Antônia Do Nascimento, Thaiz Batista Azevedo Rangel Miguel, Emilio Miguel, Alexandre Holanda Sampaio, Kyria Do Nascimento, Celso Shiniti Nagano, Benildo Sousa Cavada,
Lectin from the seeds of Dioclea lasiophylla (DlyL) was purified in a single step by affinity chromatography on a Sephadex® G-50 column. DlyL strongly agglutinated rabbit erythrocytes and was inhibited by monosaccharides (D-mannose and α-methyl-D-mannoside) and glycoproteins (ovalbumin and fetuin). Similar to other Diocleinae lectins, DlyL has three chains, α, β and γ, with mass of 25,569 ± 2, 12,998 ± 1 and 12,588 ± 1 Da, respectively, and has no disulfide bonds. The hemagglutinating activity of DlyL was ...
Tópico(s): Chromosomal and Genetic Variations
2013 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Felipe Alves Batista, Sabryna Brena Cunha Fontele, Lubna Karine Beserra Santos, Lívia Alves Filgueiras, Steffane Q. Nascimento, João Marcelo de Castro e Sousa, Juan Carlos Ramos Gonçalves, Anderson Nogueira Mendes,
The development of systems for transport and release of drugs, also known as Drug delivery system (DDS), and are being used as strategies to combat cancer. These systems can maintain drug delivery at therapeutic levels and protect it from premature degradation in the biological environment, minimizing adverse effects. Based on this, α-terpineol was encapsulated in the polymer matrix of Poly(methyl methacrylate) (PMMA) in the form of nanoparticles. Preliminarily the computational analysis of parameters ...
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2019 - Elsevier BV | Materials Today Communications
Produção Nacional
Revisado por pares
Leilane Rocha Barros Dourado, Nilva Kazue Sakomura, DÊNISSON DAVID GOMES DO NASCIMENTO, Juliano César de Paula Dorigam, Simara Márcia Marcato, João Batista Kochenborger Fernandes,
Este trabalho foi realizado para avaliar o crescimento e desempenho de duas linhagens de aves pescoço pelado. Foram utilizadas 400 aves, distribuídas em um delineamento inteiramente casualizado, os tratamentos consistiram de um esquema fatorial 2 x 2 (linhagens x sexo), com cinco repetições de 20 aves cada. Foram utilizadas aves Pescoço Pelado das linhagens Sasso e ISA Label. As aves receberam rações formuladas à base de milho e de farelo de soja para atender às exigências nutricionais. Foi determinado ...
Tópico(s): Genetic and phenotypic traits in livestock
2009 - UNIVERSIDADE FEDERAL DE LAVRAS | Ciência e Agrotecnologia
Produção Nacional
Revisado por pares
Alberto Jorge Oliveira Lopes, Cleydlenne Costa Vasconcelos, João Batista Santos Garcia, Myssa Sued Dória Pinheiro, Francisco Assis Nascimento Pereira, Darleno de Sousa Camelo, Sebastião Vieira de Morais, José Roberto Brito Freitas, Cláudia Quintino da Rocha, Maria Nilce de Sousa Ribeiro, Maria do Socorro de Sousa Cartágenes,
Bees are of great importance for plant diversity for being an important pollinating agents. Stingless bees such as Scaptotrigona affinis postica, is cultivated largely due to the products offered by it. Pollen is one of these products, which has been highlighted for exhibit various therapeutic properties. Considering the bioactivity of this natural product, this study investigated the antioxidant, anti-inflammatory, antinociceptive activities, and elucidated the chemical composition of pollen collected ...
Tópico(s): Plant and animal studies
2020 - Multidisciplinary Digital Publishing Institute | Antioxidants
Produção Nacional
Revisado por pares
Gustavo Pereira Calado, Alberto Jorge Oliveira Lopes, Lívio Martins Costa, Francisco das Chagas Alves Lima, Lucilene A. Silva, Wanderson S. Pereira, Flávia Maria Mendonça do Amaral, João Batista Santos Garcia, Maria do Socorro de S. Cartágenes, Flávia Raquel Fernandes do Nascimento,
The chronicity of osteoarthritis (OA), characterized by pain and inflammation in the joints, is linked to a glutamate receptor, N-methyl-D-aspartate (NMDA). The use of plant species such as Chenopodium ambrosioides L. (Amaranthaceae) as NMDA antagonists offers a promising perspective. This work aims to analyze the antinociceptive and anti-inflammatory responses of the crude hydroalcoholic extract (HCE) of C. ambrosioides leaves in an experimental OA model. Wistar rats were separated into six groups ( ...
Tópico(s): Ethnobotanical and Medicinal Plants Studies
2015 - Public Library of Science | PLoS ONE
Produção Nacional
Sandro Serpa, Cecília Rocha da Silva, Rosana de Sousa Campos, Francisca Bruna Stefany Aires do Nascimento, João Batista de Andrade Neto, Lisandra J da Silva, Brenda S. Gaspar, Helaine Almeida Queiroz, Fátima Daiana Dias Barroso, Jacó Ricarte Lima de Mesquita, Manoel Odorico de Moraes, Bruno C. Cavalcanti, Hemerson I. F. Magalhães, Iri Sandro Pampolha Lima, Hélio Vitoriano Nobre Júnior,
Over the past few decades, researches have reported an increased incidence of invasive candidiasis and suggested that the majority of infections produced by this pathogen are associated with biofilm growth, which are more resistant to antimicrobial agents than planktonic cells. In addition to these problems, there are few antifungal agents available and it is necessary the development of novel therapeutic strategies. In that context, this study aimed to assess the antifungal potential of ibuprofen ...
Tópico(s): Bacterial biofilms and quorum sensing
2018 - Excellent Publishers | International Journal of Current Microbiology and Applied Sciences
Produção Nacional
Revisado por pares
Clauber Mota De Sousa, Alexandre Havt, Cláudia Ferreira Santos, Francisco J. Arnaud-Batista, Karina M.A. Cunha, João Batista Gadelha de Cerqueira, Manassés Claudino Fonteles, Nilberto Robson Falcão do Nascimento,
Receptors for natriuretic peptides have been demonstrated as potential targets for the treatment of male erectile dysfunction.This study investigates the relaxant effects of the atrial natriuretic peptide (ANP) and uroguanylin (UGN), and expression of natriuretic peptide receptors on strips of human corpora cavernosa (HCC).Quantitative analysis of natriuretic receptor expression and relaxation of precontracted strips were used to assess the membrane-bound guanylate cyclase-cyclic guanosine monophosphate ( ...
Tópico(s): Urinary Bladder and Prostate Research
2010 - Elsevier BV | The Journal of Sexual Medicine
Produção Nacional
Revisado por pares
João Osvaldo Silva Campos, Francisco Wendel Batista de Aquino, Ronaldo Ferreira do Nascimento, José Galberto Martins da Costa, Denis De Keukeleire, Antônio Renato Soares de Casimiro,
Tópico(s): Plant biochemistry and biosynthesis
2004 - Elsevier BV | Journal of Food Composition and Analysis