Dalal Al‐Johar, Neptune Shinwari, Jamal M. Arif, Nasser Al‐Sanea, Alaa Abdul Jabbar, Raafat El-Sayed, Abdullah Mashhour, Grisellhi Billedo, Inaam El‐Doush, Iman Al‐Saleh,
Abstract This study examined the chemopreventive effect of Nigella sativa and some of its antioxidant constituents on a number of colon cancer biomarkers in rats induced with azoxymethane (AOM). Sixty male Sprague‐Dawley rats were randomly assigned into ten subgroups: vehicle (1–5) and experimental (6–10). The rats in each group were fed one of the following diets: basal diet, (200 mg/kg) Nigella sativa , (0.2 mg/kg) selenium, (1.2 mg/kg) all‐ trans ‐retinol plus (100 mg/kg) dl ‐ α ‐tocopherol and (10 mg/kg) ...
Tópico(s): Bioactive Compounds and Antitumor Agents
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