Åke Lernmark, Anne H. Nathans, Donald F. Steiner,
Methods have been developed for the isolation on a semi-micro scale of a plasma membrane-enriched fraction from rat islets of Langerhans. An important feature of these experiments is the use of 125I-labeled wheat germ agglutinin as a specific probe for plasma membrane-containing fractions. The partly purified plasma membrane fraction had a density in sucrose of about 1.10 and was enriched in the activities of 5'-nucleotidase, alkaline phosphatase, sodium-potassium, and magnesium-dependent ATPase ...
Tópico(s): Diabetes and associated disorders
1976 - Rockefeller University Press | The Journal of Cell Biology
David B. Sacks, Mark A. Arnold, George L. Bakris, David E. Bruns, Andrea R. Horvath, Åke Lernmark, Boyd E. Metzger, David M. Nathan, M. Sue Kirkman,
BACKGROUND Numerous laboratory tests are used in the diagnosis and management of diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. APPROACH An expert committee compiled evidence-based recommendations for laboratory analysis in screening, diagnosis, or monitoring of diabetes. The overall quality of the evidence and the strength of the recommendations were evaluated. The draft consensus recommendations were evaluated by invited reviewers ...
Tópico(s): Pancreatic function and diabetes
2023 - American Diabetes Association | Diabetes Care
Peter Bunting, Åke Rosenqvist, Lammert Hilarides, Richard Lucas, Nathan Thomas,
This study presents an updated global mangrove forest baseline for 2010: Global Mangrove Watch (GMW) v2.5. The previous GMW maps (v2.0) of the mangrove extent are currently considered the most comprehensive available global products, however areas were identified as missing or poorly mapped. Therefore, this study has updated the 2010 baseline map to increase the mapping quality and completeness of the mangrove extent. This revision resulted in an additional 2660 km2 of mangroves being mapped yielding ...
Tópico(s): Plant and Fungal Species Descriptions
2022 - Multidisciplinary Digital Publishing Institute | Remote Sensing
Peter Bunting, Åke Rosenqvist, Lammert Hilarides, Richard Lucas, Nathan Thomas, Takeo Tadono, Thomas A. Worthington, Mark Spalding, Nicholas Murray, Lisa‐Maria Rebelo,
Mangroves are a globally important ecosystem that provides a wide range of ecosystem system services, such as carbon capture and storage, coastal protection and fisheries enhancement. Mangroves have significantly reduced in global extent over the last 50 years, primarily as a result of deforestation caused by the expansion of agriculture and aquaculture in coastal environments. However, a limited number of studies have attempted to estimate changes in global mangrove extent, particularly into the ...
Tópico(s): Tropical and Extratropical Cyclones Research
2022 - Multidisciplinary Digital Publishing Institute | Remote Sensing
Thomas A. Worthington, Dominic A. Andradi‐Brown, Radhika Bhargava, Christina A. Buelow, Peter Bunting, Clare Duncan, Temilola Fatoyinbo, Daniel A. Friess, Liza Goldberg, Lammert Hilarides, David Lagomasino, Emily Landis, Kate Longley-Wood, Catherine E. Lovelock, Nicholas Murray, Siddharth Narayan, Åke Rosenqvist, Michael Sievers, Marc Simard, Nathan Thomas, P. van Eijk, Chris Zganjar, Mark Spalding,
Mangrove forests are found on sheltered coastlines in tropical, subtropical, and some warm temperate regions. These forests support unique biodiversity and provide a range of benefits to coastal communities, but as a result of large-scale conversion for aquaculture, agriculture, and urbanization, mangroves are considered increasingly threatened ecosystems. Scientific advances have led to accurate and comprehensive global datasets on mangrove extent, structure, and condition, and these can support ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2020 - Elsevier BV | One Earth
David B. Sacks, Mark A. Arnold, George L. Bakris, David E. Bruns, Andrea R. Horvath, M. Sue Kirkman, Åke Lernmark, Boyd E. Metzger, David M. Nathan,
BACKGROUND Multiple laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. APPROACH An expert committee compiled evidence-based recommendations for the use of laboratory analysis in patients with diabetes. A new system was developed to grade the overall quality of the evidence and the strength of the recommendations. A draft of the guidelines was posted on the Internet, ...
Tópico(s): Hyperglycemia and glycemic control in critically ill and hospitalized patients
2011 - American Diabetes Association | Diabetes Care
David B. Sacks, Mark A. Arnold, George L. Bakris, David E. Bruns, Andrea R. Horvath, M. Sue Kirkman, Åke Lernmark, Boyd E. Metzger, David M. Nathan,
BACKGROUND Multiple laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. APPROACH An expert committee compiled evidence-based recommendations for the use of laboratory analysis in patients with diabetes. A new system was developed to grade the overall quality of the evidence and the strength of the recommendations. A draft of the guidelines was posted on the Internet, ...
Tópico(s): Diet and metabolism studies
2011 - American Association for Clinical Chemistry | Clinical Chemistry
David B. Sacks, Mark A. Arnold, George L. Bakris, David E. Bruns, Andrea R. Horvath, M. Sue Kirkman, Åke Lernmark, Boyd E. Metzger, David M. Nathan,
BACKGROUND Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these tests varies substantially. APPROACH An expert committee compiled evidence-based recommendations for the use of laboratory testing for patients with diabetes. A new system was developed to grade the overall quality of the evidence and the strength of the recommendations. Draft guidelines were posted on the Internet and presented ...
Tópico(s): Diet and metabolism studies
2011 - American Diabetes Association | Diabetes Care
David B. Sacks, Mark A. Arnold, George L. Bakris, David E. Bruns, Andrea R. Horvath, M. Sue Kirkman, Åke Lernmark, Boyd E. Metzger, David M. Nathan,
Multiple laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially.An expert committee drafted evidence-based recommendations for the use of laboratory analysis in patients with diabetes. An external panel of experts reviewed a draft of the guidelines, which were modified in response to the reviewers' suggestions. A revised draft was posted on the Internet and was presented ...
Tópico(s): Pancreatic function and diabetes
2011 - American Association for Clinical Chemistry | Clinical Chemistry
Tuan Duc Nguyen, Nathan Hawley, Mantha S. Phanikumar,
Abstract Winter circulation exerts a strong control on the release and timing of nutrients and contaminants from bays into the adjoining lakes. To estimate winter residence times of solutes in the presence of ice cover, we used an ice model coupled to hydrodynamic, thermal and solute transport models of Saginaw Bay and Lake Huron for two low (2010 and 2013) and two high (2009 and 2014) ice years. The models were tested using temperature data from thermistor chains and current data from ADCP moorings ...
Tópico(s): Marine and coastal ecosystems
2016 - Wiley | Limnology and Oceanography
Jade E. Keehn, Nathan C. Nieto, C. Richard Tracy, C. M. Gienger, Chris R. Feldman,
Abstract Patterns of body size evolution on islands provide compelling cases of rapid and dramatic phenotypic evolution in terrestrial vertebrates, yet debate remains over the relative roles of predation and resource availability in driving such evolution. We compared the morphology of five reptile species (four lizards, one snake) from A naho I sland, a desert island in P yramid L ake, Nevada, and the nearby mainland, using museum and live‐caught animals. We also examined head‐shape allometries ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2013 - Wiley | Journal of Zoology
Peter Bunting, Åke Rosenqvist, Richard Lucas, Lisa‐Maria Rebelo, Lammert Hilarides, Nathan Thomas, Andrew Hardy, Takuya Itoh, Masanobu Shimada, C. Max Finlayson,
This study presents a new global baseline of mangrove extent for 2010 and has been released as the first output of the Global Mangrove Watch (GMW) initiative. This is the first study to apply a globally consistent and automated method for mapping mangroves, identifying a global extent of 137,600 km 2 . The overall accuracy for mangrove extent was 94.0% with a 99% likelihood that the true value is between 93.6–94.5%, using 53,878 accuracy points across 20 sites distributed globally. Using the geographic ...
Tópico(s): Coastal and Marine Dynamics
2018 - Multidisciplinary Digital Publishing Institute | Remote Sensing
John Bally, Nathaniel Cunningham, Nickolas Moeckel, Michael Burton, Nathan Smith, Adam Frank, Åke Nordlund,
The explosive BN/KL outflow emerging from OMC1 behind the Orion Nebula may have been powered by the dynamical decay of a non-hierarchical multiple system $\sim$500 years ago that ejected the massive stars I, BN, and source n, with velocities of about 10 to 30 km s$^{-1}$. New proper motion measurements of H$_2$ features show that within the errors of measurement, the outflow originated from the site of stellar ejection. Combined with published data, these measurements indicate an outflow age of $\sim$ ...
Tópico(s): Astro and Planetary Science
2011 - IOP Publishing | The Astrophysical Journal
Thomas A. Worthington, Dominic A. Andradi‐Brown, Radhika Bhargava, Christina A. Buelow, Peter Bunting, Clare Duncan, Temilola Fatoyinbo, Daniel A. Friess, Liza Goldberg, Lammert Hilarides, David Lagomasino, Emily Landis, Kate Longley-Wood, Catherine E. Lovelock, Nicholas Murray, Siddharth Narayan, Åke Rosenqvist, Michael Sievers, Marc Simard, Nathan Thomas, P. van Eijk, Chris Zganjar, Mark Spalding,
(One Earth 2, 429–443; May 22, 2020) In the preparation of the originally published perspective, text from an internal Nature Conservancy working document was unfortunately included without proper attribution to its authors, who are not co-authors of this paper. In the online version of the article, the section “Prioritization of Conservation and Rehabilitation” has now been corrected to cite the framework developed by McGowan et al. (as reference 113) and include minor text edits. In addition, the ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2020 - Elsevier BV | One Earth
Åke Lernmark, Shu Jin Chan, Rosa K. Choy, Anne H. Nathans, Raymond J. Carroll, Howard S. Tager, Arthur H. Rubenstein, Hewson H. Swift, Donald F. Steiner,
This chapter contains section titled: Early Stages in Insulin Biosynthesis-Is There a Pre-Proinsulin? Regulation of Insulin Biosynthesis and Secretion New Secretory Products of the β-Cell Precursors of Glucagon and Other Peptide Hormones Acknowledgements References Discussion References
Tópico(s): Diabetes Treatment and Management
1976 - Wiley | Novartis Foundation symposium
David B. Sacks, Mark A. Arnold, George L. Bakris, David E. Bruns, Andrea R. Horvath, Åke Lernmark, Boyd E. Metzger, David M. Nathan, M. Sue Kirkman,
BACKGROUND Numerous laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. An expert committee compiled evidence-based recommendations for laboratory analysis in patients with diabetes. The overall quality of the evidence and the strength of the recommendations were evaluated. The draft consensus recommendations were evaluated by invited reviewers and presented for ...
Tópico(s): Diet and metabolism studies
2023 - American Diabetes Association | Diabetes Care
Produção Nacional
Revisado por pares
Richard Lucas, Lisa‐Maria Rebelo, Temilola Fatoyinbo, Åke Rosenqvist, Takuya Itoh, Masanobu Shimada, Marc Simard, Pedro Walfir Martins e Souza Filho, Nathan Thomas, Carl Trettin, Arnon Accad, João M. B. Carreiras, Lammert Hilarides,
Information on the status of and changes in mangroves is required for national and international policy development, implementation and evaluation. To support these requirements, a component of the Japan Aerospace Exploration Agency’s (JAXA) Kyoto and Carbon (K&C) initiative has been to design and develop capability for a Global Mangrove Watch (GMW) that routinely monitors and reports on local to global changes in the extent of mangroves, primarily on the basis of observations by Japanese L-band ...
Tópico(s): Environmental Changes in China
2014 - CSIRO Publishing | Marine and Freshwater Research
David B. Sacks, Mark A. Arnold, George L. Bakris, David E. Bruns, Andrea R. Horvath, Åke Lernmark, Boyd E. Metzger, David M. Nathan, M. Sue Kirkman,
Abstract Background Numerous laboratory tests are used in the diagnosis and management of diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. Approach An expert committee compiled evidence-based recommendations for laboratory analysis in screening, diagnosis, or monitoring of diabetes. The overall quality of the evidence and the strength of the recommendations were evaluated. The draft consensus recommendations were evaluated by invited ...
Tópico(s): Diet and metabolism studies
2023 - American Association for Clinical Chemistry | Clinical Chemistry
Gary M. Leong, Sofia Movérare, Jesena Brce, Nathan Doyle, Klara Sjögren, Karin Dahlman‐Wright, Jan-Åke Gustafsson, Ken K. Y. Ho, Claes Ohlsson, Kin‐Chuen Leung,
Suppressors of cytokine signaling (SOCS) are important negative regulators of cytokine action. We recently reported that estrogen stimulates SOCS-2 expression and inhibits GH signaling in kidney cells. The effects of estrogen on SOCS expression in other tissues are unclear. The aim of this study was to investigate in vivo and in vitro whether estrogen affected SOCS expression in the liver, a major target organ of GH. The in vivo hepatic effects of estrogen on ovariectomized mice lacking estrogen ...
Tópico(s): Endometriosis Research and Treatment
2004 - Oxford University Press | Endocrinology
Nathan J. Proudman, Marcin Churski, Jakub W. Bubnicki, Jan-Åke Nilsson, Dries P. J. Kuijper,
Abstract ContextUngulate prey can use increased vigilance to reduce their risk of predation, but little is known of the combined and interactive risk effects from humans and wolves in determining ungulate behaviour across time and space. Understanding the interplay between these risk effects is increasingly important, considering the recolonisation of several large carnivores to more human-dominated landscapes in Europe. AimThe aim of the present study was to assess the vigilance behaviour expressed ...
Tópico(s): Ecology and biodiversity studies
2020 - CSIRO Publishing | Wildlife Research
Nathan Thomas, Peter Bunting, Richard Lucas, Andrew Hardy, Åke Rosenqvist, Temilola Fatoyinbo,
This study demonstrates a globally applicable method for monitoring mangrove forest extent at high spatial resolution. A 2010 mangrove baseline was classified for 16 study areas using a combination of ALOS PALSAR and Landsat composite imagery within a random forests classifier. A novel map-to-image change method was used to detect annual and decadal changes in extent using ALOS PALSAR/JERS-1 imagery. The map-to-image method presented makes fewer assumptions of the data than existing methods, is ...
Tópico(s): Plant and Fungal Species Descriptions
2018 - Multidisciplinary Digital Publishing Institute | Remote Sensing
Nathan Thomas, Richard Lucas, Peter Bunting, Andrew Hardy, Åke Rosenqvist, Marc Simard,
For the period 1996-2010, we provide the first indication of the drivers behind mangrove land cover and land use change across the (pan-)tropics using time-series Japanese Earth Resources Satellite (JERS-1) Synthetic Aperture Radar (SAR) and Advanced Land Observing Satellite (ALOS) Phased Array-type L-band SAR (PALSAR) data. Multi-temporal radar mosaics were manually interpreted for evidence of loss and gain in forest extent and its associated driver. Mangrove loss as a consequence of human activities ...
Tópico(s): Plant and Fungal Species Descriptions
2017 - Public Library of Science | PLoS ONE
Richard Harding, Åke Mattsson, Michael Nathan, James G. Kavanaugh,
Tópico(s): Early Childhood Education and Development
1979 - Elsevier BV | General Hospital Psychiatry
Julia K. Morgan, Evan A. Solomon, Åke Fagereng, H. M. Savage, Maomao Wang, Francesca Meneghini, Philip M. Barnes, Rebecca Bell, Melodie French, Nathan L. Bangs, Hiroko Kitajima, D. M. Saffer, Laura Wallace,
IODP Site U1518, drilled during IODP Expeditions 372 and 375, penetrated a large-offset (∼6 km) thrust, the Pāpaku fault, rising from a megathrust that hosts recurring slow slip events along the Hikurangi margin. Although drilling intersected the fault zone at only ∼300 m below the seafloor within porous silty mudstone, it exhibits intense tectonic ductile deformation, including finely banded mudstones contorted into decimeter-scale folds; elongate mudstone clasts with grain tail complexes; stacked ...
Tópico(s): Methane Hydrates and Related Phenomena
2022 - Elsevier BV | Earth and Planetary Science Letters
Nathan Hilbert, Jennifer Evans-Cowley, Jason Reece, Christy Rogers, Wendy Ake, Casey W. Hoy,
We present a new method for analyzing spatial variation in the cost of a balanced diet, as an alternative to food desert classification. Our specific hypothesis is that the cost of a balanced diet varies according to where one lives, as a function of travel and food item costs. We collected price data for the USDA Thrifty Food Plan from approximately 30 percent of food retail outlets of various kinds in the three Gulf Coast counties of Mississippi, and these prices were extrapolated to the remaining ...
Tópico(s): Obesity, Physical Activity, Diet
2014 - Thomas A. Lyson Center for Civic Agriculture and Food Systems | Journal of Agriculture Food Systems and Community Development
Nathan Thomas, Richard Lucas, Takuya Itoh, Marc Simard, Temilola Fatoyinbo, Peter Bunting, Åke Rosenqvist,
Tópico(s): Flood Risk Assessment and Management
2014 - Springer Science+Business Media | Wetlands Ecology and Management
Produção Nacional
Revisado por pares
Jonathan Lazar, Julio Abascal, Simone Diniz Junqueira Barbosa, Jeremy Barksdale, Batya Friedman, Jens Großklags, Jan Gulliksen, JEFF JOHNSON, Tom McEwan, Loïc Martínez Normand, Wibke Michalk, Janice Tsai, Gerrit C. van der Veer, Hans von Axelson, Åke Walldius, Gill Whitney, Marco Winckler, Volker Wulf, Elizabeth F. Churchill, Lorrie Faith Cranor, Janet Davis, Alan Hedge, Harry Hochheiser, Juan Pablo Hourcade, Clayton Lewis, Lisa P. Nathan, Fabio Paternò, Blake E. Reid, Whitney Quesenbery, Ted Selker, Brian Wentz,
This monograph lays out a discussion framework for understanding the role of human–computer interaction HCI in public policymaking. We take an international view, discussing potential areas for research and application, and their potential for impact. Little has been written about the intersection of HCI and public policy; existing reports typically focus on one specific policy issue or incident. To date, there has been no overarching view of the areas of existing impact and potential impact. We ...
Tópico(s): Usability and User Interface Design
2016 - Now Publishers | Foundations and Trends® in Human–Computer Interaction
Klarie M. Ake, Nathan D’Amico, Katelyn E. Grimes, Megan E. Mormile, Douglas W. Powell, Thomas A. Buckley, Barry A. Munkasy, Nicholas G. Murray,
Dual-task (DT) scenarios, which increase cognitive load, may be a method of assessing gait abnormalities in concussed athletes during walking. This may be a means of objectively differentiating between healthy and concussed athletes during the acute phase of recovery. PURPOSE: The purpose of this study was to examine the effect of DT scenarios on gait in concussed athletes (CA) within 48 hours of the concussive injury as compared to a group of healthy athletes. METHODS: Gait parameters of 24 collegiate ...
Tópico(s): Cardiovascular Effects of Exercise
2016 - Lippincott Williams & Wilkins | Medicine & Science in Sports & Exercise
Katelyn E. Grimes, Eric D. Shiflett, Barry A. Munkasy, Klarie M. Ake, Nathan D’Amico, Megan E. Mormile, Douglas W. Powell, Thomas A. Buckley, Nicholas G. Murray,
PURPOSE: The purpose of this study was to investigate the potential differences of cumulative and mean linear acceleration magnitudes (LA) over the course of a single football season between positions (line vs. skill) and participation settings (games vs. practice). METHODS: Thirty-two NCAA Division I football players were fitted with Head Impact Telemetry (HIT) System sensors to measure acceleration forces associated with a head impact (player vs. player or contact with ground). LA were recorded for ...
Tópico(s): Traumatic Brain Injury Research
2016 - Lippincott Williams & Wilkins | Medicine & Science in Sports & Exercise
Nicholas G. Murray, Eric D. Shiflett, Barry A. Munkasy, Katelyn E. Grimes, Klarie E. Ake, Nathan D’Amico, Megan E. Mormile, Douglas W. Powell, Thomas A. Buckley,
Evidence suggests that a concussive blow negatively impacts the postural control system post-injury. However, little is known regarding the role of repetitive head impacts on posture over the course of one athletic season. PURPOSE: The purpose of this study was to investigate changes in the postural control system after a season of repetitive head impacts (RHI) in Division 1 football athletes using traditional and nontraditional measures of posture. METHODS: Fourteen Division I football players (CON) ( ...
Tópico(s): Traumatic Brain Injury Research
2016 - Lippincott Williams & Wilkins | Medicine & Science in Sports & Exercise