Wesleyan, Traveler, Liberator, Joseph Sturge, Roch. Dem., John P. Raymond, John Jolliffe, Isreal Taylor, A. D., Philip C. Schuyler, Nubia, J. R. J., A. B. S., An Old Practitioner, Wilmington Independent, Norristown Olive Branch, Alice Carey, Horace Greeley, Rev. John Hessel,
... New York, Another batch of claimants to the McDonough estate have sprung up, Slavery as It is "How Long O Lord?", Neal Dow, The Lexington Convention, Just to the Point. ...
1855 - Gale Group | SAS Part 1
Lei Sun, Tiffany Pham, Timothy T. Cornell, Kelli McDonough, Walker McHugh, Neal B. Blatt, Mary K. Dahmer, Thomas P. Shanley,
Abstract Protein phosphatase 2A (PP2A) is a member of the intracellular serine/threonine phosphatases. Innate immune cell activation triggered by pathogen-associated molecular patterns is mediated by various protein kinases, and PP2A plays a counter-regulatory role by deactivating these kinases. In this study, we generated a conditional knockout of the α isoform of the catalytic subunit of PP2A (PP2ACα). After crossing with myeloid-specific cre-expressing mice, effective gene knockout was achieved ...
Tópico(s): interferon and immune responses
2016 - American Association of Immunologists | The Journal of Immunology
Jonathan Northcroft, P B, Waldemar Januszczak, John Dugdale, Hala Jaber, J Norman, Dr David Lowry, David Brown, Helen Davies, Nicholas Rufford, Rob Hughes, John Peter, V S, Emma Moore, Amanda Ursell, Jonathan Miller, Ben Gelbum, George Garland, Adam Zamoyski, Adam Sweeting, J D, Emme Moore, Peter Wade, Roger McGough's, Frank Whitford, Kieran McCarthy, Nicola Venning, Kathryn Cooper, Alasdair Reld, Reland White, Tim Richards, Rory Godson, Gillian Hall, Frederic Raphael, Neil Wormald, E P, Andrew Sullivan, Clive Davis, Guy Dennis, John Lynch, Alice B-B, Richard Herring, Joseph Dunn, Tony Allen-Mills, Simon Wilde, Martin James, Barrie Parr, Tom Walker, Anthony Sattin, Robert Winnett, Tom Rigby, Irwin Stelzer, Sally kinners, Peter Wilson, Rosie Millard, Tom McEnaney, Luclnda Kemeny, David Dougill, John McKay, Neal Baldwin, John Gribbin, Philip Kingsley, John Waples Deputy Business Editor, Philip Kerr, Geraldine Hackett, Alan Frame, Marcus Tanner, David Hewson, Grace Ciappara, Barry Hugill, Cally Law, Jonathon Carr-Brown, Alasdair Reid, Hugh Canning, David Caims, Colin Mehigan, Jeremy Clarkson, Stewart Lee, Edward Porter, Victoria Segal, Joe Swift, Helen Kenny, Richard Events, Eben Black, Liz Edwards, George Perry, Adam Nathan, Nick Gardner, Paul Bailey, Graham Norton, Stefan Holter, Stuart Wavell, Christopher Silvester, George Miller, Alastair Hendy, Vincent Crump, Maria Grachvogel, Joan Lingard, Hugh McIlvanney, Chris Woodhead, Jonathan Todd, Dennis Ruston, Lucinda Kemeny, Peter Small, Jasper Gerard, Paul Driver, Ken Martin, Michael Woodhead, John Humphrys, Charlie Catchpole, Nicholas Hellen, Richard Brooks, John Follain, Johan Cruyff, Ian Hawkey, Simon Fanshawe, Cosmo landesman, Christopher Morgan, David Leppard, John Douce, Katie Hickman, Tony Fearon, Terence Jones, Brenda Maddox, Laurie Graham, Amber Cowan, Mark Edwards, Tilly Bagshawe, Susan Clark, Eben Black Chief Political Correspondent, Danny O'Brien, Stave Grant, Victoria O'Brien, Nigel Freeman, Vicki Clifford, Raymond Keene, Ed Vaizey, Gareth Huw Davies, Cosmo Landesman, Marie Colvin, Diana Wright, David Orr, Debble Atkinson, Stephen Jones, Dominic O'Connell, Alexis Giles, Louise Armitstead, Uzi Mahnaimi, Nick Cain, Peta Bee, Judith Prescott, Natalie Graham, Steven Rose, M J, Kate Rew, Nigel Blagg, Colin McDOWELL, Gordon Musson, David Walsh, Jonas Bernstein, Nicolas Batfour, Stephen Armstrong, John Elliott, Dan Claims, Victoria O'brien, Helen Chrislett, Quentin Peck, Roland White, Garth Alexander, Tom Hunter, Simon Braund, Rory Godson Business Editor, Monica Littleboy, Maurice Chittenden, Bill Gorman, Richard Brooks Arts Editor, Richard Rae, Mark Franchetti, L Cox-Freeman, Ray Hutton, Martin Ivens, James Hughes, Dennis Yates, Louise Armistead, Frank Fitzgibbon, Michael Fitzpatrick, Mr Arafat, Saily Kinnes, Leah Hardy, John Harlow, Mrs Eleanor Coker, Godfrey Smith, Robert Winnett Consumer Affairs Correspondent, Jack Haigh, Bethan Ryder, Barry Collins, Gillian Wilmot, J Blackwell, John Waples, A A Gill, Ros Dodd, Heather Mills, Matthew Campbell, Brian Glanville, John Carey, Robert Barrie, Tom Robbins, Alex Leach, Ray O'Brien, James Hardwick, Jools Holland, Jonathan Carr-Brown, Will Iredale, Mathew Cambell, Maria McErlane, Hazel Curry, Ann McFerran, Jason Corcoran, R H, Naomi Caine, David Wickers, Simon Spilsbury, Hugh Thomson, Michael Clower, Minette Marrin, Alan Scaife, Mark Hodson, Graham Norwood, David Powell, Joe Lovejoy, Jonathan Futrell, Shelley Von Strunckel, Rupert Steiner, Philip Bobbitt, David Budworth, Hugh Pearman, Michael Kerr, Peter Horner, Dea Birkett, David Harbord, Tom Deveson, Julie Brooke, Penny Perrick, Lee Carter, Simon Crerar, Mrs Mills, Martin Ray Philbert, Sarah Baxter, Brian Schofield, Martin Booth, James Wright, Joanna Simon, Chris Feetenby, India Knight, Steve Grant, Simon Bevan, Sandy Gall, Meera Mahida, Dan Pearson, Dominic Rushe, Boris Schapiro,
... Terminator Shakey: Nell Young's Biography by Jimmy McDonough Cape £20 pp786 Lindsey Davis Pulsating A little ...
2002 - Gale Group | Sunday Times HA GDA
Parth Patel, Kaoru Ito, Jon A. L. Willcox, Alireza Haghighi, Min Young Jang, Joshua M. Gorham, Steven R. DePalma, Lien Lam, Barbara McDonough, Renée Johnson, Neal K. Lakdawala, Amy E. Roberts, Paul J.R. Barton, Stuart A. Cook, Diane Fatkin, Christine E. Seidman, Jonathan G. Seidman,
Heterozygous TTN truncating variants cause 10% to 20% of idiopathic dilated cardiomyopathy (DCM). Although variants which disrupt canonical splice signals (ie, invariant dinucleotide of the splice donor site, invariant dinucleotide of the splice acceptor site) at exon-intron junctions are readily recognized as TTN truncating variants, the effects of other nearby sequence variations on splicing and their contribution to disease is uncertain.Rare variants of unknown significance located in the splice ...
Tópico(s): Cardiac Structural Anomalies and Repair
2021 - Wolters Kluwer | Circulation Genomic and Precision Medicine
Robyn J. Hylind, Virginie Beauséjour-Ladouceur, Molly Plovanich, Adam Helms, Eric D. Smith, Emer Joyce, Scott R. Granter, Lynne W. Stevenson, Allison L. Cirino, Barbara McDonough, Arash Mostaghimi, Dominic J. Abrams, Neal K. Lakdawala,
... Stevenson, MD, Allison L. Cirino, MS, Barbara A. McDonough, RN, Arash Mostaghimi, MD, MPA, MPH, Dominic J. Abrams, MD and Neal K. Lakdawala, MD Robyn HylindRobyn Hylind Inherited Cardiac ...
Tópico(s): Sports injuries and prevention
2020 - Wolters Kluwer | Circulation Genomic and Precision Medicine
Miguel A. Trujillo, Michael O’Neal, Sean M. McDonough, Rui Qin, John C. Morris,
The sodium iodide symporter (NIS) directs the uptake and concentration of iodide in thyroid cells. We have extended the use of NIS-mediated radioiodine therapy to other types of cancer, we transferred and expressed the NIS gene into prostate, colon and breast cancer cells using adenoviral vectors. To improve vector efficiency we have developed a conditionally replicating adenovirus (CRAd) in which the E1a gene is driven by the prostate-specific promoter, Probasin and the cassette RSV promoter human ...
Tópico(s): Molecular Biology Techniques and Applications
2010 - Springer Nature | Gene Therapy
María A. Trujillo, Michael O’Neal, Sean M. McDonough, Rui Qin, John C. Morris,
The sodium-iodide symporter (NIS) directs the uptake and concentration of iodide in thyroid cells. We have extended the use of NIS-mediated radioiodine therapy to prostate cancer. We have developed a prostate tumor specific conditionally replicating adenovirus that expresses hNIS (Ad5PB_RSV-NIS). For radiovirotherapy to be effective in humans, the radioiodine dose administered in the pre-clinical animal model should scale to the range of acceptable doses in humans. We performed 131I dose-response ...
Tópico(s): Radiation Therapy and Dosimetry
2012 - Springer Nature | Cancer Gene Therapy
Neal Shepherd, Holly B. McDonough,
We have estimated the rate of diffusion of calcium ions in the transverse tubules of isolated cardiocytes by recording changes in peak calcium current ( I Ca ) caused by rapid changes of the extracellular calcium concentration ([Ca] o ) at various intervals just preceding activation of I Ca . Isolated ventricular cells of guinea pig heart and atrial cells from rabbit heart were voltage-clamped (whole cell patch), superfused at a high flow rate, and stimulated continuously with depolarizing pulses (0.5 Hz, 200- ...
Tópico(s): Protein Structure and Dynamics
1998 - American Physical Society | AJP Heart and Circulatory Physiology
Allison L. Cirino, Neal K. Lakdawala, Barbara McDonough, Lauren Conner, Dale Adler, Mark S. Weinfeld, Patrick T. O’Gara, Heidi L. Rehm, Kalotina Machini, Matthew S. Lebo, Carrie L. Blout Zawatsky, Robert C. Green, Calum A. MacRae, Christine E. Seidman, Carolyn Y. Ho,
As DNA sequencing costs decline, genetic testing options have expanded. Whole exome sequencing and whole genome sequencing (WGS) are entering clinical use, posing questions about their incremental value compared with disease-specific multigene panels that have been the cornerstone of genetic testing.Forty-one patients with hypertrophic cardiomyopathy who had undergone targeted hypertrophic cardiomyopathy genetic testing (either multigene panel or familial variant test) were recruited into the MedSeq ...
Tópico(s): Trypanosoma species research and implications
2017 - Lippincott Williams & Wilkins | Circulation Cardiovascular Genetics
Arie Franco, Leonard Allen Yontz, Suash Sharma, Kristopher Neal Lewis, Colleen H. McDonough,
Rosai-Dorfman disease (RDD) involves abnormal proliferations of oddly behaving histocytes that are not derived from the Langerhan's Cell linage. These collections tend to occur within lymph nodes, with occasional extra nodal presentation. While RDD is a rare entity itself, extra nodal cases are even more so, with even fewer reporting cardiac involvement, and previously only in adults. This report describes the disease in a pediatric patient who had the unique feature of an extra nodal cardiac mass. ...
Tópico(s): RNA modifications and cancer
2012 - EduRad Publishing | Journal of Radiology Case Reports
Sheila M. Marcus, Juan F. López, Susan C. McDonough, Michael J. MacKenzie, Heather A. Flynn, Charles R. Neal, Sheila Gahagan, Brenda L. Volling, Niko Kaciroti, Delia M. Vázquez,
To explore the interplay of maternal depressive symptoms on the infant limbic-hypothalamic-pituitary axis (LHPA) and neurological development. Pregnant women were monitored for depressive symptoms using the Beck Depression Inventory (BDI) at 28, 32, and 37 weeks of gestation and at delivery. A mixture growth curve analysis divided the women into three risk groups: low/stable, intermediate, and high/increasing depression based on BDI scores. The infant neuroendocrine system was examined using cord ...
Tópico(s): Infant Development and Preterm Care
2010 - Elsevier BV | Infant Behavior and Development
Miguel A. Trujillo, Michael O’Neal, Samantha J. McDonough, John C. Morris,
We have constructed a prostate tumor-specific conditionally replicating adenovirus (CRAd), named Ad5PB_RSV-NIS, which expresses the human sodium iodine symporter (NIS) gene. LNCaP tumors were established in nude mice and infected with this CRAd to study tumor viral spread, NIS expression, and efficacy. Using quantitative PCR, we found a linear correlation between the viral dose and viral genome copy numbers recovered after tumor infection. Confocal microscopy showed a linear correlation between adenovirus ...
Tópico(s): Sarcoma Diagnosis and Treatment
2012 - Springer Nature | Gene Therapy
Matthew Ashbrook, Kelli McDonough, J J Pituch, Patricia L. Christopherson, Timothy T. Cornell, David T. Selewski, Thomas P. Shanley, Neal B. Blatt,
Summary Citrate, a central component of cellular metabolism, is a widely used anti-coagulant due to its ability to chelate calcium. Adenosine triphosphate (ATP)-citrate lyase, which metabolizes citrate, has been shown to be essential for inflammation, but the ability of exogenous citrate to impact inflammatory signalling cascades remains largely unknown. We hypothesized that citrate would modulate inflammatory responses as both a cellular metabolite and calcium chelator, and tested this hypothesis ...
Tópico(s): Phagocytosis and Immune Regulation
2015 - Oxford University Press | Clinical & Experimental Immunology
Michael O’Neal, Miguel A. Trujillo, Julia Davydova, Samantha J. McDonough, Masato Yamamoto, John C. Morris,
Prostate cancer (PCa) is the second most commonly diagnosed and sixth leading cause of cancer death in American men and one for which no curative therapy exists after metastasis. To meet this need for novel therapies, our laboratory has previously generated conditionally replicating adenovirus (CRAd) vectors expressing the sodium iodide symporter (hNIS). This virus transduced PCa cells and induced functional NIS expression, allowing for noninvasive tumor imaging and combination therapy with radioiodide, ...
Tópico(s): RNA Interference and Gene Delivery
2012 - Mary Ann Liebert, Inc. | Human Gene Therapy
Produção Nacional
Revisado por pares
Giuliana G. Repetti, Yuri Kim, Alexandre C. Pereira, Jodie Ingles, Mark W. Russell, Neal K. Lakdawala, Carolyn Y. Ho, Sharlene M. Day, Christopher Semsarian, Barbara McDonough, Steven R. DePalma, Daniel Quiat, Eric M. Green, Christine E. Seidman, Jonathan G. Seidman,
Significance Genetics, notably pathogenic genetic variants in sarcomere protein genes, play a major role in development of hypertrophic cardiomyopathy (HCM). However, degree of contribution from epigenetic and environmental factors in clinical presentation of HCM is currently unclear. We investigated phenotypic differences between identical twins with pathogenic sarcomere protein gene variants and demonstrated their discordant HCM presentation despite having virtually identical genomes. Our study ...
Tópico(s): Studies on Chitinases and Chitosanases
2021 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Michael O’Neal, María A. Trujillo, Julia Davydova, Samantha J. McDonough, Masato Yamamoto, John C. Morris,
Our laboratory has investigated replicating adenovirus-human sodium iodide symporter (Ad-hNIS) vectors in a combinatorial oncolytic approach known as radiovirotherapy. However, hNIS-mediated iodide sequestration requires an intact cell membrane, and the enhancement of infectivity may alter the radioiodide accumulation in vivo. To assess these effects, we constructed Ad-NIS vectors expressing NIS from the major late promoter. Viral tropism was altered using a hybrid Ad5/3 fiber, and rates of viral ...
Tópico(s): Cancer Research and Treatments
2013 - Springer Nature | Cancer Gene Therapy
Neal K. Lakdawala, Jens Jakob Thune, Steven D. Colan, Allison L. Cirino, Faranak Farrohi, Jose Rivero, Barbara McDonough, Elizabeth Sparks, E. John Orav, Jonathan G. Seidman, Christine E. Seidman, Carolyn Y. Ho,
Background— Sarcomere mutations cause both dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM); however, the steps leading from mutation to disease are not well described. By studying mutation carriers before a clinical diagnosis develops, we characterize the early manifestations of sarcomere mutations in DCM and investigate how these manifestations differ from sarcomere mutations associated with HCM. Methods and Results— Sixty-two genotyped individuals in families with sarcomeric DCM ...
Tópico(s): Cardiovascular Effects of Exercise
2012 - Lippincott Williams & Wilkins | Circulation Cardiovascular Genetics
Daniel S. Herman, Lien Lam, Matthew R.G. Taylor, Libin Wang, Polakit Teekakirikul, Danos C. Christodoulou, Lauren Conner, Steven R. DePalma, Barbara McDonough, Elizabeth Sparks, Debbie Lin Teodorescu, Allison L. Cirino, Nicholas R. Banner, Dudley J. Pennell, Sharon Graw, Marco Merlo, Andrea Di Lenarda, Gianfranco Sinagra, J. Martijn Bos, Michael J. Ackerman, Richard N. Mitchell, Charles E. Murry, Neal K. Lakdawala, Carolyn Y. Ho, Paul J.R. Barton, Stuart A. Cook, Luisa Mestroni, Jonathan G. Seidman, Christine E. Seidman,
Dilated cardiomyopathy and hypertrophic cardiomyopathy arise from mutations in many genes. TTN, the gene encoding the sarcomere protein titin, has been insufficiently analyzed for cardiomyopathy mutations because of its enormous size.
Tópico(s): Viral Infections and Immunology Research
2012 - Massachusetts Medical Society | New England Journal of Medicine
Bruce D. Gelb, Christine E. Seidman,
... Monafo A, Roberts A, Stryker J, Seidman C, McDonough B, Seidman J, Goldmuntz E, Edman S, Garbarini J, Hakonarson H, Mercer-Rosa L, Mitchell L, Tusi J, White P, Woyciechowski S, Chung W, Warburton D, Awad D, Celia K, Etwaru D, Sond J, Kline J, Korsin R, Lanz A, Marquez E, Williams I, Wilpers A, Yee R, Gelb B, Guevara D, Julian A, Mac Neal M, Mintz C, Peter I, Sachidanandam R, Seiden ...
Tópico(s): RNA modifications and cancer
2012 - Lippincott Williams & Wilkins | Circulation Cardiovascular Genetics
Ivan Crozier, Susan Hardy, D.B. Rutledge, Niall Shanks, Ian J. Slater, Daryn Lehoux, Alan Chalmers, Shaughan Lavine, Richard McDonough, Paul Redding, Katherine Neal, David J. Stump, Nicolas Rasmussen, Fa‐ti Fan, David Oldroyd, Iain Davidson, Hanne Andersen, Vassiliki Betty Smocovitis, Ivan Crozier, Anjan Chakravartty, King’s College, John Laurent, Ian Tyrell, Susan Spath, Roy MacLeod,
2001 - Springer Science+Business Media | Metascience
Ray R. Larson, Jerome McDonough, Paul O’Leary, Lucy Kuntz, Ralph H. Moon,
... 4600.Search for more papers by this authorJerome McDonough, Jerome McDonough School of Information Management and Systems, University of ... 4600.Search for more papers by this authorJerome McDonough, Jerome McDonough School of Information Management and Systems, University of ... Using online catalogs: A nationwide survey. New York: Neal-Schuman Publishers. Ousterhout, J. K. (1994). Tcl and ...
Tópico(s): Mathematics, Computing, and Information Processing
1996 - Wiley | Journal of the American Society for Information Science
Anita T. Layton, Jennifer C. Sullivan,
... Allen AM, Haase VH, Snouwaert JN, Le TH, McDonough AA, Koller BH, Coffman TM. AT1A angiotensin receptors ... 00543.2015. Link | ISI | Google Scholar18. Li Q, McDonough AA, Layton HE, Layton AT. Functional implications of ... RC, Pastor-Soler N, Arranz CT, Yu ASL, McDonough AA. Sexual dimorphic pattern of renal transporters and ... Riquier-Brison, Wilhelm Kriz, Brigitte Kaissling, Christopher R. Neal, Kenton P. Arkill, Nariman Ahmadi, Inderbir S. Gill, ...
Tópico(s): Birth, Development, and Health
2018 - American Physical Society | AJP Renal Physiology
Julia Davydova, Miguel A. Trujillo, Michael O’Neal, Samantha J. McDonough, Stephen Nelson, Joohee Han, John C. Morris, Selwyn M. Vickers, Masato Yamamoto,
Tópico(s): Animal Genetics and Reproduction
2012 - Elsevier BV | Gastroenterology
Julia Davydova, María A. Trujillo, Michael O’Neal, Samantha J. McDonough, Joohee Han, Selwyn M. Vickers, John C. Morris, Masato Yamamoto,
Circulating polymorphonuclear leukocytes (PMNLs) may contribute to development of organ dysfunction in acute pancreatitis (AP). We outlined aberrations in PMNL signaling profiles in patients with AP complicated by organ dysfunction and immune suppression.Study comprised 13 patients treated at intensive care unit due to severe AP complicated by vital organ dysfunction. Mean proportion (SEM) of HLA-DR-positive monocytes was 55.0% (4.1%). 13 healthy volunteers served as reference subjects. Phosphorylation ...
Tópico(s): Phagocytosis and Immune Regulation
2013 - Elsevier BV | Pancreatology
Sabrina Paganoni, Fabiola De Marchi, James Chan, Sara Thrower, Nathan P. Staff, Neil Datta, Yaz Y. Kisanuki, Vivian E. Drory, Christina N. Fournier, Erik P. Pioro, Stephen A. Goutman, Nazem Atassi, Maryangel Jeon, Sarah Caldwell, Timothy McDonough, Caroline Gentile, Jianing Liu, M.F. Turner, Carol Denny, Kevin J. Felice, Misty Green, Stephanie Scarberry, Saad Abu-Saleh, Beatrice Nefussy, Debbie Hastings, S. K. Kim, Blake Swihart, Ximena Arcila-Londono, Daniel S. Newman, Michael G. Silverman, Angela Genge, Kristiana Salmon, Lauren Elman, Leo McCluskey, Kelly Almasy, Marc Gotkine, Kimberly Goslin, A. J. CUMMINGS, Eli K. Edwards, Michael H. Rivner, Kristy Bouchard, Brandy Quarles, Justin Kwan, Matthew Jaffa, Robert H. Baloh, Peggy Allred, David Walk, Samuel Maiser, Georgios Manousakis, Valerie Ferment, J. Americo Fernandes, Pariwat Thaisetthawatkul, Deborah Heimes, Melissa Phillips, Laura Sams, Melissa Kahler, Alecia Corcoran, Daniel G. Larriviere, Sadie Chotto, Gracy Juba,
Primary lateral sclerosis (PLS) is a neurodegenerative disease characterized by progressive upper motor neuron dysfunction. Because PLS patients represent only 1 to 4% of patients with adult motor neuron diseases, there is limited information about the disease's natural history. The objective of this study was to establish a large multicenter retrospective longitudinal registry of PLS patients seen at Northeast ALS Consortium (NEALS) sites to better characterize the natural progression of PLS. Methods: ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2020 - Taylor & Francis | Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
... doi.org/10.1111/1467-9256.00077 Kevin McDonough Can the Liberal State Support Cultural Identity Schools?, ... 397–420.https://doi.org/10.2307/3235313Patrick Neal Perfectionism With a Liberal Face? Nervous Liberals and ...
Tópico(s): War, Ethics, and Justification
1989 - University of Chicago Press | Ethics
Taylor M. Triolo, Alexandra Fouts, Laura Pyle, Liping Yu, Peter A. Gottlieb, Andrea K. Steck, Carla J. Greenbaum, Mark A. Atkinson, David A. Baidal, Manuela Battaglia, Dorothy J. Becker, P. J. Bingley, Emanuele Bosi, Jane H. Buckner, Mark A. Clements, Peter G. Colman, Linda A. DiMeglio, Stephen E. Gitelman, Robin Goland, Peter A. Gottlieb, Kevan C. Herold, Mikael Knip, J. Krischer, Åke Lernmark, W. Moore, Antoinette Moran, Andrew Muir, James L. Palmer, Mark Peakman, Louis H. Philipson, P. Raskin, María J. Redondo, Henry Rodriguez, William E. Russell, Lisa M. Spain, Desmond Schatz, Jay M. Sosenko, John M. Wentworth, Diane K. Wherrett, Darrell M. Wilson, William E. Winter, Anette‐Gabriele Ziegler, Mark S. Anderson, Peter A. Antinozzi, Christophe Benoist, Janice S. Blum, Katarzyna Bourcier, Peter Chase, Michael Clare‐Salzler, Raphael Clynes, George S. Eisenbarth, C. Garrison Fathman, Gilman D. Grave, Bernhard J. Hering, Richard A. Insel, Francine Kaufman, Tom Kay, Ellen W. Leschek, J. Mahon, Jennifer B. Marks, Kirsti Näntö‐Salonen, Gerald T. Nepom, Tihamer Orban, Robertson Parkman, Mark D. Pescovitz, John Peyman, Alberto Pugliese, Bart O. Roep, Maria Grazia Roncarolo, Peter J. Savage, Olli Simell, Robert Sherwin, Mark Siegelman, Jay S. Skyler, Andrea K. Steck, James W. Thomas, Massimo Trucco, J. Richard Wagner, Jeffrey P. Krischer, Ellen W. Leschek, Lisa Rafkin, Katarzyna Bourcier, Catherine C. Cowie, Mary A. Foulkes, Richard A. Insel, Heidi Krause‐Steinrauf, John M. Lachin, Saúl Malozowski, John Peyman, J P Ridge, Peter J. Savage, Jay S. Skyler, Stephanie J. Zafonte, Lisa Rafkin, Jay M. Sosenko, Norma S. Kenyon, Irene Santiago, Jeffrey P. Krischer, Brian N. Bundy, Michael Abbondondolo, Timothy E. Adams, Darlene Amado, Ilma Asif, Matthew Boonstra, Cristina Burroughs, David Cuthbertson, Mary Deemer, Christopher Eberhard, Steve Fiske, Julie Ford, Jennifer Garmeson, Heather Guillette, Susan Geyer, Brian Hays, Courtney Henderson, Martha Henry, Kathleen Heyman, Belinda Hsiao, Christina Karges, Nichole Keaton, Amanda Kinderman, Pat Law, Ashely Leinbach, Shu Liu, Jennifer Lloyd, Jamie Malloy, Kristin Maddox, Julie Martin, Jessica Miller, Éric Milliot, Margaret Moore, Sarah Müller, Thuy Trang Nguyen, Ryan O’Donnell, Amy L. Roberts, Kelly Sadler, Tina Stavros, Roy Tamura, Keith Wood, Ping Xu, Kenneth C. Young, Persida Alies, Franz Badias, Aaron Baker, Monica Bassi, Craig A. Beam, David Boulware, London Bounmananh, Susan Bream, Doug Freeman, Jessica Gough, Jinin Ginem, Moriah Granger, Mary Holloway Michelle Kieffer, Page Lane, Cristin Linton, Lavanya Nallamshetty, Vanessa Oduah, Yazandra Parrimon, Kate Paulus, Jennifer Pilger, Joy Ramiro, AQesha Luvon Ritzie, Archana Sharma, Audrey Shor, Xiaohong Song, AMANDA M. TERRY, Jeanne Weinberger, Margaret Wootten, John M. Lachin, Mary A. Foulkes, Pamela Harding, Heidi Krause‐Steinrauf, Susan McDonough, Paula McGee, Kimberly Owens Hess, Donna Phoebus, Scott Quinlan, Erica Raiden, Emily Batts, Chris Buddy, Kristin Kirpatrick, Mary Ramey, Ann Shultz, Chris Webb, Melita Romesco, Judith Fradkin, Ellen W. Leschek, Lisa M. Spain, Peter J. Savage, Sean Aas, Emily A. Blumberg, Gerald J. Beck, David J. Brillon, Rose Gubitosi‐Klug, Lori M. Laffel, Robert A. Vigersky, D. H. Wallace, Jonathan Braun, Åke Lernmark, Bernard C. Lo, Herman Mitchell, Ali Naji, Jørn Nerup, Trevor J. Orchard, Michael W. Steffes, Anastasios A. Tsiatis, Robert M. Veatch, Bernard Zinman, Brett Loechelt, Lindsey R. Baden, Michael J. Green, Adriana Weinberg, Santica Marcovina, Jerry P. Palmer, Adriana Weinberg, Liping Yu, Sunanda Babu, William E. Winter, George S. Eisenbarth, Polly J. Bingley, Raphael Clynes, Linda A. DiMeglio, George S. Eisenbarth, Brian Hays, Ellen W. Leschek, Jennifer B. Marks, Della Matheson, Lisa Rafkin, Henry Rodriguez, Lisa M. Spain, Darrell M. Wilson, María J. Redondo, David Gómez, Andrene McDonald, Sandra Lidia Peralta Peña, Massimo Pietropaolo, Kathy Shippy, Emily Batts, Tyler Brown, Jane H. Buckner, Angela Dove, Marissa Hammond, Deborah Hefty, Jani Klein, Kristen Kuhns, McKenzie Letlau, Sandra Lord, Marli McCulloch‐Olson, Lisa M. Miller, Gerald T. Nepom, Jared Odegard, Mary Ramey, Elaine Sachter, Marissa St. Marie, Kimberly Stickney, Dana VanBuecken, Ben Vellek, Christine A. Webber, Laurie Allen, Jenna Bollyk, Nicole Hilderman, Hebatullah Ismail, Steve Lamola, Srinath Sanda, Heather Vendettuoli, David Tridgell, Roshanak Monzavi, Meredith Bock, Lynda K. Fisher, Mary Halvorson, Debra Jeandron, Mimi S. Kim, Jamie Wood, Mitchell E. Geffner, Francine Kaufman, Robertson Parkman, Christine Salazar, Robin Goland, Raphael Clynes, Steve Cook, Matthew Freeby, Mary Gallagher, Rachelle Gandica, Ellen Greenberg, Amy Kurland, Sarah Pollak, Amy Wolk, Mary Chan, Linda Koplimae, Elizabeth Levine, Kelly Smith, Jeniece Trast, Linda A. DiMeglio, Janice S. Blum, Carmella Evans‐Molina,
OBJECTIVE There are variable reports of risk of concordance for progression to islet autoantibodies and type 1 diabetes in identical twins after one twin is diagnosed. We examined development of positive autoantibodies and type 1 diabetes and the effects of genetic factors and common environment on autoantibody positivity in identical twins, nonidentical twins, and full siblings. RESEARCH DESIGN AND METHODS Subjects from the TrialNet Pathway to Prevention Study (N = 48,026) were screened from 2004 ...
American Diabetes Association
Daniel W. Jones, Friedrich C. Luft, Paul K. Whelton, Michael H. Alderman, John E. Hall, Eric D. Peterson, Robert M. Califf, David A. McCarron,
... Dec-2019. Frame A, Farquhar W, Latulippe M, McDonough A, Wainford R and Wynne B (2019) Moving ...
Tópico(s): Hormonal Regulation and Hypertension
2018 - Lippincott Williams & Wilkins | Hypertension
Produção Nacional
Revisado por pares
Arthur Pancioli, Opeolu Adeoye, Pamela Schmit, Jane Khoury, Steven R. Levine, Thomas A. Tomsick, Heidi Sucharew, Claudette E. Brooks, Todd J. Crocco, Laurie Gutmann, Thomas Hemmen, Scott E. Kasner, Dawn Kleindorfer, William A. Knight, Sharyl Martini, James S. McKinney, William J. Meurer, Brett C. Meyer, Alexander Schneider, Phillip Scott, Sidney Starkman, Steven Warach, Joseph P. Broderick, Arthur Pancioli, Opeolu Adeoye, Joseph P. Broderick, Pamela Schmit, Jane Khoury, Heidi Sucharew, Scott Janis, Thomas A. Tomsick, Claudette E. Brooks, Todd J. Crocco, Thomas Hemmen, Scott E. Kasner, James S. McKinney, William J. Meurer, Alex Schneider, Sidney Starkman, Steven Warach, Steven R. Levine, Claudia S. Moy, K.M.A. Welch, Gretchen E. Tietjen, William R. Clarke, Jordan Bonomo, Erin McDonough, Simona Ferioli, Felipe de los Rios De la Rosa, Sharyl Martini, Daniel Woo, Rachel Garvin, Dawn Kleindorfer, Pooja Khatri, Anna Gensic, Matthew L. Flaherty, Daniel Kanter, Brett Kissela, Brian Stettler, Jason Mackey, Rhonda Cadena, Shannon Kohake, Laura Heitsch, Samir Belagaje, Achala Vagal, John M. Hallenbeck, Richard Benson, Amie W. Hsia, Rakesh Jaitly, Lawrence L. Latour, John Lynch, José Luís Merino, Ravi S. Menon, Jason Freeman, Alejandro Magadán, Nandakumar Magaraja, Jennifer Jothen, Bonanle Famakin, Shlee Song, Alex Katcheves, Zurab Nadareishvili, C L Ritter, William G. Barsan, Devin Brown, Lewis B. Morgenstern, Robert Silbergleit, Venkatakrishna Rajajee, Lesli Rusche-Skolarus, J. R. Burke, Jeffrey J. Fletcher, Eric E. Adelman, Michael Ke Wang, Darin Zahuranec, Brett Cucchiara, Steven R. Messé, Christina Wilson, Koto Ishida, Michael Mullen, Jonathan M. Raser, Swaroop Pawar, David Rose, Neelofer Shafi, Igor Rybinnik, Michael McGavery, Lauren A. Beslow, Lauren Sansing, Latisha K. Ali, Hermelinda Abcede, Peter G. Adamczyk, William Buxton, Michael T. Froehler, Doojin Kim, David S. Liebeskind, Bruce Ovbiagele, Verna R. Porter, Venkatakrishna Rajajee, Neal Rao, Radoslav Raychev, Sarah Song, Jeffrey L. Saver, Matthew Tenser, Shamsha Velani, Anil Yallapragada, Brett C. Meyer, Any Guzik, Kiet Loc, Dawn Meyer, Gilda Tafreshi, Jessica Choe, Ajeet Sodhi, Patrick Delaney, Sean Evans, Omar Ghausi, Nhu Bruce, Will Neil, Brank Huisa, Andrew Stemer, Reid Taylor, Jeanette Larson, Seth Larson, Rodney Leacock, Subasisni Dash, Robert Eisenstein, Raffi Kapitanyan, Ugo Paolucci, Chirag Shah, Win Toe, John Brick, O. Ll. Lander, Hollynn Larrabee, Laurie Gutmann, Joseph Minardi, Allison Tadros, Roger Tillotson, Charles Whiteman, Debra J. Paulson, Rosanna Sikora, Christopher Cummings, John Burt Foster, Janice Carrozzella, Traci Doellman, Irene Ewing, Jamey Frasure, Gerald Goodall, Pamela Kimmel, Judith Spilker, Robert Tamer, Peggy Waymeyer, Joyce Zeigler, Lisa Davis, Saman Farsad, Teresa Morella, Allison M. Kade, Shirley Frederiksen, Mary Liz, Jean M. Luciano, Judy Guzy, Ileana Grunberg, Teresa Rzesiewicz, Karen Rapp, Tracy Nanney, Leslie E. Shell, Margaret Perkins, Cindy Benton, Robin Jones, Lynne C. Hampton, Claudine Cuento, Rachel Alosky, Stephanie A. Shepard, Michelle Moccio, Catherine Albrecht, Yaritza Rosario, D. Caputo, Stephen M. Davis, Patricia Altemus, Martha Power, Reyna VanGilder, Jay Sherman, Taura L. Barr,
In a previous study, 0.3 and 0.45 mg/kg of intravenous recombinant tissue plasminogen activator (rt-PA) were safe when combined with eptifibatide 75 mcg/kg bolus and a 2-hour infusion (0.75 mcg/kg per minute). The Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke-Enhanced Regimen (CLEAR-ER) trial sought to determine the safety of a higher-dose regimen and to establish evidence for a phase III trial.CLEAR-ER was a multicenter, double-blind, randomized safety study. ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2013 - Lippincott Williams & Wilkins | Stroke
Barry Castro, Kenneth Weingarten,
... 10.1007/978-4-431-71307-4_2Terrence McDonough Of Rats and Economists, Journal of the History ...
Tópico(s): Software Engineering Research
1970 - University of Chicago Press | Journal of Political Economy