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Artigo Acesso aberto Revisado por pares

William J. Sandborn, Darrell S. Pardi,

... Scopus (288) Google Scholar, 20Sambuelli A. Boerr L. Negreira S. Gil A. Camartino G. Huernos S. Kogan ... day is described below.20Sambuelli A. Boerr L. Negreira S. Gil A. Camartino G. Huernos S. Kogan ... Scopus (288) Google Scholar, 20Sambuelli A. Boerr L. Negreira S. Gil A. Camartino G. Huernos S. Kogan ... Scopus (288) Google Scholar, 20Sambuelli A. Boerr L. Negreira S. Gil A. Camartino G. Huernos S. Kogan ... for budesonide and metronidazole.20Sambuelli A. Boerr L. Negreira S. Gil A. Camartino G. Huernos S. Kogan ...

Tópico(s): Inflammatory Bowel Disease

2004 - Elsevier BV | Gastroenterology

Artigo Acesso aberto Revisado por pares

Martín Negreira Caamaño, Jesús Piqueras‐Flores, Jorge Martínez-Del-Río, Patricia Nieto-Sandoval-Martín-de-la-Sierra, Daniel Águila‐Gordo, Cristina Mateo-Gómez, Daniel Salas-Bravo, Marta Rodríguez Martínez, Martín Negreira Caamaño,

Concerns have been raised about the possible harmfulness of angiotensin-converter enzyme inhibitors (ACEi) and aldosterone receptor blockers (ARB) in patients with COVID-19. However, few data from a European population have been published, especially from hypertensive patients. To study the association between ACEi or ARB treatments and major adverse outcomes during hospitalisation in COVID-19 patients. We studied 545 consecutive hypertensive patients admitted to our institution due to COVID-19 with ...

Tópico(s): Blood Pressure and Hypertension Studies

2020 - Adis, Springer Healthcare | High Blood Pressure & Cardiovascular Prevention

Artigo Acesso aberto Revisado por pares

Mariann R. Weierich, Christopher I. Wright, Alyson Negreira, Brad C. Dickerson, Lisa Feldman Barrett,

Many neuroscience studies have demonstrated that the human amygdala is a central element in the neural workspace that computes affective value. Emerging evidence suggests that novelty is an affective dimension that engages the amygdala independently of other affective properties. This current study is the first in which novelty, valence, and arousal were systematically examined for their relative contributions to amygdala activation during affective processing. Healthy young adults viewed International ...

Tópico(s): Functional Brain Connectivity Studies

2009 - Elsevier BV | NeuroImage

Artigo Revisado por pares

Noelia Negreira, I. Rodrı́guez, E. Rubí, R. Cela,

A simple, inexpensive sample preparation procedure, based on the matrix solid-phase dispersion (MSPD) technique, for the determination of six UV filters: 2-ethylhexyl salicylate (EHS), 3,3,5-trimethylcyclohexyl salicylate (Homosalate, HMS), 3-(4-methylbenzylidene) camphor (4-MBC), isoamyl-p-methoxycinnamate (IAMC), 2-ethylhexyl-p-methoxycinnamate (EHMC) and octocrylene (OCR), in dust from indoor environments is presented and the influence of several operational parameters on the extraction performance ...

Tópico(s): Air Quality and Health Impacts

2009 - Elsevier BV | Journal of Chromatography A

Artigo Revisado por pares

Noelia Negreira, I. Rodrı́guez, M. Ramil, E. Rubí, R. Cela,

A sensitive procedure for the determination of three UV filters: ethylhexyl salicylate (EHS), 3,3,5-trimethylcyclohexyl salicylate (Homosalate, HMS), 2-hydroxy-4-methoxybenzophenone (BP-3) and two related hydroxylated benzophenones (2,4-dihydroxybenzophenone, BP-1 and 2,2′-dihydroxy-4-methoxybenzophenone, BP-8) in water samples is presented. Analytes were first concentrated on the coating of a solid-phase microextraction (SPME) fibre, on-fibre silylated and then determined using gas chromatography combined ...

Tópico(s): Biosensors and Analytical Detection

2009 - Elsevier BV | Analytica Chimica Acta

Artigo Revisado por pares

Nicolás Benech, Stéfan Catheline, Javier Brum, Thomas Gallot, Carlos Negreira,

One-channel time-reversal (TR) experiments allow focalization of waves in reverberant cavities. According to the Rayleigh criterion, the focal spot width is directly related to the wavelength and therefore depends on the mechanical properties of the medium. Thus, the general idea of this work is to extract quantitative estimations of these mechanical properties using a time-reversal approach based on cross-correlations of the wave field. An external source creates mechanical waves in the audible ...

Tópico(s): Geophysical Methods and Applications

2009 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control

Artigo Revisado por pares

Xiaoxing Ke, Sara Bals, Ainhoa Romo Negreira, Thomas Hantschel, H. Bender, Gustaaf Van Tendeloo,

A powerful method to study carbon nanotubes (CNTs) grown in patterned substrates for potential interconnects applications is transmission electron microscopy (TEM). However, high-quality TEM samples are necessary for such a study. Here, TEM specimen preparation by focused ion beam (FIB) has been used to obtain lamellae of patterned samples containing CNTs grown inside contact holes. A dual-cap Pt protection layer and an extensive 5 kV cleaning procedure are applied in order to preserve the CNTs and ...

Tópico(s): Force Microscopy Techniques and Applications

2009 - Elsevier BV | Ultramicroscopy

Artigo Acesso aberto Revisado por pares

Alicia M. Sambuelli, Luis A. Boerr, Silvia Negreira, Ángel Gil, G Camartino, Sergio P. Huernos, Zulema Kogan, Ana Cabanne, A Graziano, H.A. Peredo, Ivan Doldan, Ofelia González, Emilia Sugai, M Lumi, Jie Bai,

Background: Pouchitis has been suggested to be a recurrence of ulcerative colitis in a colon‐like mucosa. Topical steroids are a valid therapeutic alternative for distal forms of ulcerative colitis. Aim: To investigate the efficacy and tolerability of budesonide enema in the treatment of pouchitis compared with oral metronidazole. Materials and methods: Twenty‐six patients with an active episode of pouchitis (defined as a pouchitis disease activity index score ≥ 7) and no treatment during the previous ...

Tópico(s): Helicobacter pylori-related gastroenterology studies

2002 - Wiley | Alimentary Pharmacology & Therapeutics

Artigo Revisado por pares

Gabriel Montaldo, Philippe Roux, Arnaud Derode, Carlos Negreira, Mathias Fink,

The building of high-power ultrasonic sources from piezoelectric ceramics is limited by the maximum voltage that the ceramics can endure. We have conceived a device that uses a small number of piezoelectric transducers fastened to a cylindrical metallic waveguide. A one-bit time- reversal operation transforms the long-lasting low-level dispersed wave forms into a sharp pulse, thus taking advantage of dispersion to generate high-power ultrasound. The pressure amplitude that is generated at the focus ...

Tópico(s): Ultrasound and Cavitation Phenomena

2002 - American Institute of Physics | Applied Physics Letters

Carta Acesso aberto Revisado por pares

Alberto Avolio,

... Florio L, Olascoaga A, Brum J, Alallón W, Negreira C, Lluberas R and Armentano R (2011) Integrated ...

Tópico(s): Heart Rate Variability and Autonomic Control

2008 - Lippincott Williams & Wilkins | Hypertension

Artigo Revisado por pares

Sebastian Diecke, Angel Quiroga‐Negreira, Torben Redmer, Daniel Besser,

Human embryonic stem cells (hESCs) can be maintained undifferentiated (pluripotent) or differentiated to basically all functional cell types, depending on the culture conditions used. Culture of hESCs in the presence of medium conditioned by mouse embryonic fibroblasts (MEFs) can be used to keep hESCs undifferentiated. This observation suggests that MEFs produce factors required for the pluripotency of hESCs. The data presented here show that fibroblast growth factor 2 (FGF2) treatment of MEFs is crucial ...

Tópico(s): Mesenchymal stem cell research

2008 - Karger Publishers | Cells Tissues Organs

Artigo Acesso aberto Revisado por pares

Christopher I. Wright, Alyson Negreira, Andrea L. Gold, Jennifer C. Britton, Danielle M. Williams, Lisa Feldman Barrett,

The human amygdala preferentially responds to objects of potential value, such as hedonically valenced and novel stimuli. Many studies have documented age-related differences in amygdala responses to valenced stimuli, but relatively little is known about age-related changes in the amygdala's response to novelty. This study examines whether there are differences in amygdala novelty responses in two different age groups. Healthy young and elderly adults viewed both young and elderly faces that were ...

Tópico(s): Aging and Gerontology Research

2008 - Elsevier BV | NeuroImage

Artigo Revisado por pares

Javier Brum, Stéfan Catheline, Nicolás Benech, Carlos Negreira,

In this work the shear elasticity of soft solids is measured from the surface wave speed estimation. An external source creates mechanical waves which are detected using acoustic sensors. The surface wave speed estimation is extracted from the complex reverberated elastic field through a time-reversal analysis. Measurements in a hard and a soft gelatin-based phantom are validated by independent transient elastography estimations. In contrast with other elasticity assessment methods, one advantage ...

Tópico(s): Photoacoustic and Ultrasonic Imaging

2008 - Acoustical Society of America | The Journal of the Acoustical Society of America

Artigo Revisado por pares

Stéfan Catheline, Nicolás Benech, Javier Brum, Carlos Negreira,

When a scalar far-field wave is time reversed, it starts to converge toward its initial point source location, then collapses and finally diverges. Without evanescent waves, the symmetric focus spot is limited by the Rayleigh criterion. We present an experimental observation of a time-reversal elastic wave in a soft solid cavity using the transient elastography technique. It is observed that the time-reversed far field wave collapses and gives birth to near fieldlike effects. Elastodynamic Green' ...

Tópico(s): Microwave Imaging and Scattering Analysis

2008 - American Physical Society | Physical Review Letters

Carta Acesso aberto Revisado por pares

Michael F. O’Rourke,

... FiguresReferencesRelatedDetailsCited By Bernal M, Saldarriaga J, Cabeza C, Negreira C, Bustamante J and Brum J (2019) Development ...

Tópico(s): Dementia and Cognitive Impairment Research

2008 - Lippincott Williams & Wilkins | Hypertension

Artigo Acesso aberto Revisado por pares

Liang Wang, Alyson Negreira, Peter S. LaViolette, Akram Bakkour, Reisa A. Sperling, Bradford C. Dickerson,

Abstract When given challenging episodic memory tasks, young adults demonstrate notable individual differences in performance. Recent evidence suggests that individual differences in human behavior may be related to the strength of functional connectivity of large‐scale functional networks as measured by spontaneous fluctuations in regional brain activity during quiet wakefulness (the “resting state”), in the absence of task performance. In this study, we sought to determine whether individual differences ...

Tópico(s): Neural dynamics and brain function

2010 - Wiley | Hippocampus

Artigo Acesso aberto

Javier Brum, Daniel Bia, Nicolás Benech, G. Balay, Ricardo L. Armentano, Carlos Negreira,

In this work a circulating loop capable of mimicking the physiological pressure and flow conditions inside a vessel is set up. The circulating loop consists of an artificial heart coupled to a perfusion line made of polyethylene and silicon. The artificial heart is driven by a pneumatic pump which provides the desired heart rate, pressure values and length of the systolic and diastolic period of each cycle. To measure the changes in diameter of the segment under study, an ultrasonic probe in pulse ...

Tópico(s): Cardiovascular Function and Risk Factors

2010 - Elsevier BV | Physics Procedia

Artigo Revisado por pares

Noelia Negreira, I. Rodrı́guez, E. Rubí, R. Cela,

This work presents an effective sample preparation method for the determination of eight UV filter compounds, belonging to different chemical classes, in freeze-dried sludge samples. Pressurized liquid extraction (PLE) and gas chromatography–mass spectrometry (GC–MS) were selected as extraction and determination techniques, respectively. Normal-phase, reversed-phase and anionic exchange materials were tested as clean-up sorbents to reduce the complexity of raw PLE extracts. Under final working conditions, ...

Tópico(s): Photodynamic Therapy Research Studies

2010 - Elsevier BV | Journal of Chromatography A

Artigo Revisado por pares

Nicolás Benech, Carlos Negreira,

In this paper 1D transient elastography was employed in fresh bovine skeletal muscle samples to assess the shear elastic modulus mu while the tissue was locally heated by means of an electrical resistance. The investigation is based on the study of the time shift of the shear wave propagation produced by the local temperature variation. The experiments show that the thermal expansion contribution to the time shift is negligible when compared with the shear wave speed variation. In such a case, the ...

Tópico(s): Photoacoustic and Ultrasonic Imaging

2010 - IOP Publishing | Physics in Medicine and Biology

Artigo Acesso aberto Revisado por pares

Yoshiya Moriguchi, Alyson Negreira, Mariann R. Weierich, Rebecca Dautoff, Bradford C. Dickerson, Christopher I. Wright, Lisa Feldman Barrett,

Emerging evidence indicates that stimulus novelty is affectively potent and reliably engages the amygdala and other portions of the affective workspace in the brain. Using fMRI, we examined whether novel stimuli remain affectively salient across the lifespan, and therefore, whether novelty processing--a potentially survival-relevant function--is preserved with aging. Nineteen young and 22 older healthy adults were scanned during observing novel and familiar affective pictures while estimating their ...

Tópico(s): Memory and Neural Mechanisms

2010 - The MIT Press | Journal of Cognitive Neuroscience

Artigo Acesso aberto

Javier Brum, G. Balay, Daniel Bia, Nicolás Benech, A. Ramos, Ricardo L. Armentano, Carlos Negreira,

In this work the radial displacement of the arterial wall is measured using a cross correlation algorithm. An elastic model for static pressure conditions is developed, fit to the boundary conditions of the physical problem. Measuring the wall displacements as pressure changes the biomechanical behavior of the arterial wall can be characterized. Validation measurements were performed in a calibrated latex tube. The obtained experimental results are in good agreement with the theoretical model. Human ...

Tópico(s): Ultrasound Imaging and Elastography

2010 - Elsevier BV | Physics Procedia

Artigo Acesso aberto Revisado por pares

Marta German-Diaz, Rosa Pavo-Garcia, Judit Díaz-Díaz, Elisa Giangaspro-Corradi, Sagrario Negreira-Cepeda,

Neurologic complications have been described previously in association with seasonal influenza A or B viruses, but the frequency with which these occur with novel influenza A (H1N1) virus infection is unknown. We describe a case of an adolescent with a bizarre neuropsychiatric picture associated with novel influenza A (H1N1) virus infection.

Tópico(s): Viral Infections and Immunology Research

2010 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal

Artigo Acesso aberto Revisado por pares

Daisy Sapolsky, Akram Bakkour, Alyson Negreira, P. Nalipinski, Sandra Weıntraub, M.‐Marsel Mesulam, David Caplan, Bradford C. Dickerson,

To test the validity and reliability of a new measure of clinical impairment in primary progressive aphasia (PPA), the Progressive Aphasia Severity Scale (PASS), and to investigate relationships with MRI-based cortical thickness biomarkers for localizing and quantifying the severity of anatomic abnormalities.Patients with PPA were rated using the PASS and underwent performance-based language testing and MRI scans that were processed for cortical thickness measures.The level of impairment in PASS fluency, ...

Tópico(s): Acute Ischemic Stroke Management

2010 - Lippincott Williams & Wilkins | Neurology

Artigo Revisado por pares

Noelia Negreira, P. Canosa, I. Rodrı́guez, M. Ramil, E. Rubí, R. Cela,

This work studies the stability of three UV filters: 2-ethylhexyl salicylate (ES), 2-ethylhexyl 4-(dimethylamino) benzoate (EHPABA) and 2-hydroxy-4-methoxybenzophenone (BP-3), in water samples containing low concentrations of free chlorine. Moreover, 2,4-dihydroxybenzophenone (2,4-DHBP), a metabolite of BP-3, was also included in some of the performed assays. Experiments were carried out considering free chlorine and analytes concentrations at the μg mL−1 and ng mL−1 level, respectively. Gas chromatography ...

Tópico(s): Photodynamic Therapy Research Studies

2007 - Elsevier BV | Journal of Chromatography A

Artigo Revisado por pares

Juan J. Picazo, Jesús Ruíz-Contreras, Juan Casado‐Flores, Sagrario Negreira, Fernando del Castillo, Teresa Hernández‐Sampelayo, Mercedes Bueno, Cristina Calvo, Esther Ríos, Cristina Méndez,

In October 2006, the heptavalent pneumococcal conjugate vaccine was included in the Madrid vaccination calendar, warranting serotype (St) surveillances in pneumococcal pediatric parapneumonic empyema (PPE).A prospective 2-year (May 2007-April 2009) laboratory-confirmed PPE surveillance was performed in 22 hospitals. All isolates (for serotyping) and culture-negative pleural fluids were sent to the reference laboratory for polymerase chain reaction (PCR) analysis.We identified 138 PPEs. Pneumococcal etiology ...

Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment

2011 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal

Artigo Revisado por pares

Noelia Negreira, I. Rodrı́guez, E. Rubí, R. Cela,

Tópico(s): Advanced Chemical Sensor Technologies

2011 - Springer Science+Business Media | Analytical and Bioanalytical Chemistry

Artigo Revisado por pares

Jennifer Wilcox, Erik C. Rupp, Samantha C. Ying, Dong–Hee Lim, Ana Suarez Negreira, Abby Kirchofer, Feng Feng, Kyoungjin Lee,

Preventing the release of mercury from coal-fired power plants continues to be a challenge. The design of effective and affordable control strategies depends upon the speciation of mercury from the high temperature region of the boiler to the lower temperature environment of the stack. Both homogeneous and heterogeneous oxidation pathways play a role in determining mercury's speciation over the temperature range of coal-fired flue gas. This review explores the current state of knowledge associated ...

Tópico(s): Toxic Organic Pollutants Impact

2011 - Elsevier BV | International Journal of Coal Geology