
Elisângela Vitória Adôrno, Ângela Zanette, Isa Menezes Lyra, Cyntia Cajado de Souza, Leandro Ferraz Santos, Joelma Figueiredo Menezes, Marie France Dupuit, Mari Ney Tavares Almeida, Mitermayer Galvão dos Reis, Marilda de Souza Gonçalves,
The βS‐globin haplotypes were studied in 78 sickle cell Brazilian patients from Bahia, Northeast Brazil, that has a large population of African origin. Hemoglobin (Hb) profiles were developed by high‐performance liquid chromatography (HPLC), and βS‐globin gene haplotypes were determined by polymerase chain reaction‐restriction fragment length polymorphism (PCR‐RFLP) techniques. We identified 44 (55.0%) patients with the CAR/Ben (Central African Republic/Benin) genotype, 16 (20.0%) Ben/Ben, 13 (16.2%) CAR/ ...
Tópico(s): Iron Metabolism and Disorders
2004 - Taylor & Francis | Hemoglobin

Ana Verena Galvão-Castro, Ney Boa‐Sorte, Ramon A Kruschewsky, Maria Fernanda Rios Grassi, Bernardo Galvão–Castro,
Tópico(s): T-cell and Retrovirus Studies
2011 - Springer Science+Business Media | Quality of Life Research

Ney Boa‐Sorte, Ana Verena Galvão-Castro, Danilo Borba, Renan Barbalho Nunes de Castro Lima, Bernardo Galvão–Castro,
To investigate the role of demographic variables in the relationship between the presence of HAM/TSP and current major depression.
Tópico(s): T-cell and Retrovirus Studies
2015 - Elsevier BV | The Brazilian Journal of Infectious Diseases

G. Sampaio, Jéssica Ramos Ribeiro, Celso Nascimento de Almeida, Ney Boa‐Sorte, Bernardo Galvão‐Castro, Maria Fernanda Rios Grassi, Katia Nunes Sá, Cristiane Maria Carvalho Costa Dias,
In 2012, the number of people infected with human T cell lymphotropic virus type 1 (HTLV-1) was estimated to be 10 million worldwide. Prevalence varies according to geographic location, ethnic factors, sex, age, populations exposed to risk factors, income, and education, reaching countries with the worst socioeconomic scenarios. There is a need to determine the current global prevalence of HTLV-1 and examine its association with countries' human development index (HDI) to provide data for global health ...
Tópico(s): Vector-Borne Animal Diseases
2022 - Mary Ann Liebert, Inc. | AIDS Research and Human Retroviruses

Fábio David Couto, Wendell Vilas Boas, Isa Menezes Lyra, Ângela Zanette, Marie France Dupuit, Mari Ney Tavares Almeida, Mitermayer Galvão dos Reis, Marilda de Souza Gonçalves,
The C677T methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and the G20210A mutation at the 3' untranslated region (3'UTR) of the prothrombin gene may be considered to be genetic risk factors that contribute to the clinical heterogeneity in sickle cell disease. The current study investigated a group of sickle cell (SS) patients from Salvador-Bahia, Northeast Brazil in order to determine the prevalence of these polymorphisms, using the polymerase chain reaction (PCR) and restriction fragment ...
Tópico(s): Iron Metabolism and Disorders
2004 - Taylor & Francis | Hemoglobin

Adenilda Lima Lopes Martins, Maria Fernanda Rios Grassi, Alisson de Aquino Firmino, Jean Paulo Lacerda Araújo, Taiane Silva Paixão, Bernardo Galvão‐Castro, Ney Boa‐Sorte,
Human T-lymphotropic virus (HTLV)-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neurological disorder that mostly affects women. This disease is characterized by a progressive loss of motor function and disruptions in sensory function in the lower limbs. HTLV-1 is also associated with isolated neurologic dysfunctions, overactive bladder, and erectile dysfunction. The occurrence of sexual dysfunction in HTLV-1-infected women remain unclear.To investigate associations between HTLV- ...
Tópico(s): T-cell and Retrovirus Studies
2018 - Elsevier BV | Sexual Medicine

Augusto Mota, Ceuci Nunes, Adriana Suely de Oliveira Melo, Maura Romeo, Ney Boa‐Sorte, Inês Dourado, Luíz Carlos Júnior Alcântara, Bernardo Galvão–Castro,
Previous data suggest that Salvador, the capital of the State of Bahia, a northeastern state of Brazil, has the highest prevalence of HTLV infection in blood donors among Brazilian cities. The aim of this case-control study was to identify the determinants of risk for HTLV infection among blood donors in the city of Salvador. Between January 2000 and December 2003, 504 blood donors with positive screening tests for HTLV infection (unconfirmed prevalence of 0.48%) were invited to participate in our ...
Tópico(s): Rural Development and Agriculture
2006 - Elsevier BV | Revista Brasileira de Hematologia e Hemoterapia

Andréa Mendonça Gusmão Cunha, Adele Caterino‐de‐Araujo, S.C.B. Costa, Elizabeth de los Santos‐Fortuna, Ney Boa‐Sorte, Marilda de Souza Gonçalves, F. F. Costa, Bernardo Galvão–Castro,
Human herpesvirus 8 (HHV-8) seroprevalences were determined in two isolated Amazon Amerindian tribes, according to age, gender and familial aggregation. Plasma and serum samples obtained from 982 Amazon Amerindians (664 Tiriyó and 318 Waiampi) were tested for antibodies against lytic and latent HHV-8 antigens by using 'in-house' immunofluorescence assays. Overall, HHV-8 seroprevalence was 56.8 % (57.4 % in the Tiriyó tribe and 55.7 % in the Waiampi tribe). Seroprevalence was independent of gender and increased ...
Tópico(s): Parvovirus B19 Infection Studies
2005 - Microbiology Society | Journal of General Virology

José Veríssimo Fernandes, Thales Allyrio Araújo de Medeiros Fernandes, Jenner Chrystian Veríssimo de Azevedo, Ricardo Ney Cobucci, Maria Goretti Freire de Carvalho, Vânia Sousa Andrade, Josélio Maria Galvão de Araújo,
Inflammation is a defense strategy against invading agents and harmful molecules that is activated immediately following a stimulus, and involves the release of cytokines and chemokines, which activate the innate immune response. These mediators act together to increase blood flow and vascular permeability, facilitating recruitment of effector cells to the site of injury. Following resolution of the injury and removal of the stimulus, inflammation is disabled, but if the stimulus persists, inflammation ...
Tópico(s): Reproductive System and Pregnancy
2015 - Spandidos Publishing | Oncology Letters

Vanessa Da Silva Brito, Fred Luciano Neves Santos, Noilson Lázaro Gonçalves, Théssika Hialla Almeida Araújo, Davi Silva Vale Nascimento, Felicidade Mota Pereira, Ney Boa‐Sorte, Maria Fernanda Rios Grassi, Adele Caterino‐de‐Araujo, Bernardo Galvão–Castro,
Serological screening for human T-cell lymphotropic virus type 1 (HTLV-1) is usually performed using enzyme-linked immunosorbent assay (ELISA), particle agglutination, or chemiluminescence assay kits. Due to an antigen matrix improvement entailing the use of new HTLV antigens and changes in the format of HTLV screening tests, as well as newly introduced chemiluminescence assays (CLIAs), a systematic evaluation of the accuracy of currently available commercial tests is warranted.
Tópico(s): Animal Disease Management and Epidemiology
2018 - American Society for Microbiology | Journal of Clinical Microbiology

Paulo Magalhães, Cleine Aglacy Nunes Miranda, Érika Galvão Lima, Raíza Nara Cunha Moizéis, Diego Breno Soares de Lima, Ricardo Ney Cobucci, Thales Allyrio Araújo de Medeiros Fernandes, Jenner Chrystian Veríssimo de Azevedo, Paulo Roberto Medeiros de Azevedo, Josélio Maria Galvão de Araújo, José Veríssimo Fernandes,
Tópico(s): Genital Health and Disease
2014 - Springer Science+Business Media | Archives of Gynecology and Obstetrics

Ney Boa‐Sorte, Antônio Purificação, Tatiana Amorim, Lorena Assunção, Alan Reis, Bernardo Galvão‐Castro,
Screening for vertically transmitted infection is mandatory and must be conducted at the first prenatal consultation. The most vulnerable women's groups are those at the lowest socio-economic level. Dried blood spot testing on filter paper could represent a secure way to screen pregnant women in the prenatal period.A cross-sectional study was conducted between November 2009 and March 2010, in the Metropolitan Region of Salvador, Bahia, Brazil, to compare the accuracy of the dried blood spot in filter ...
Tópico(s): HIV/AIDS Research and Interventions
2014 - Elsevier BV | The Brazilian Journal of Infectious Diseases

Marco Antônio Gomes Mello, Aline Oliveira da Conceição, Sandra Mara Bispo Sousa, Luíz Carlos Júnior Alcântara, Lauro Juliano Marin, Mônica Regina da Silva Raiol, Ney Boa‐Sorte, Lucas Pereira Souza Santos, Maria da Conceição Chagas de Almeida, Tâmara Coutinho Galvão, Raquel Gois Bastos, Noilson Lázaro, Bernardo Galvão–Castro, Sandra Rocha Gadelha,
As the most frequent pathway of vertical transmission of HTLV-1 is breast-feeding, and considering the higher prevalence in women, it is very important to perform screening examinations for anti-HTLV-1 antibodies as part of routine prenatal care. So far, no studies of HTLV-1 seroprevalence in pregnant women in the Southern region of Bahia, Brazil, have been described. Pregnant women were selected at the two regional reference centers for health care from Southern Bahia. A total of 2766 pregnant ...
Tópico(s): Animal Disease Management and Epidemiology
2014 - BioMed Central | Virology Journal

Regina Helena Rathsam-Pinheiro, Ney Boa‐Sorte, Cristina Castro-Lima-Vargens, Carlos Aldir Pinheiro, Humberto Castro‐Lima, Bernardo Galvão‐Castro,
In order to determine the prevalence of ocular lesions in HTLV-1 infected patients in Salvador Bahia, a transversal study was conducted on 140 HTLV-1 infected patients (90 asymptomatic and 50 tropical spastic paraparesis/HTLV-1-associated myelopathy) between June 2004 and November 2005. The ophthalmological examination included visual acuity measurement, ocular motility, biomicroscopy of the anterior and posterior chambers, intraocular pressure and evaluation of lachrymal secretion. Observation verified ...
Tópico(s): Rural Development and Agriculture
2009 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical

Ivanoska Moxoto, Ney Boa‐Sorte, Ceuci Nunes, Augusto Mota, A. M. Dumas, Inês Dourado, Bernardo Galvão‐Castro,
O objetivo foi descrever as características sociodemográficas, epidemiológicas e comportamentais de mulheres infectadas (64) e não infectadas (66) pelo HTLV-1 em Salvador, Bahia. O diagnóstico sorológico foi obtido por ELISA, WB e Imunofluorescência. Dados epidemiológicos e sociodemográficos foram coletados utilizando questionário padronizado. O Qui-quadrado ou teste de Fisher foi usado para dados categóricos e ANOVA ou Kruskall Wallis (3 grupos) e teste T ou Mann Whitney (2 grupos) para os dados contínuos. ...
Tópico(s): Animal Disease Management and Epidemiology
2007 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical

Fernanda Mara Fernandes, Anderson Rocha Aguiar, Laryssa Pinheiro Costa Silva, Thiago Senna, Ingrid Ney Kramer de Mello, Thaís de Oliveira, Samuel Galvão de Freitas, Wendeo Ferreira da Silveira, Fábio Ribeiro Braga, Jackson Víctor de Araújo,
This study aimed to evaluate the efficacy of the association of the nematophagous fungi (Duddingtonia flagrans-AC001); (Pochonia chlamydosporia-VC4) and (Arthrobotrys robusta-I31) in a pelletised formulation of a sodium alginate matrix. The viability and activity of pellet germination and fungal activity (after encapsulation) were evaluated using in vitro and in vivo tests. Next, 12 heads of cattle, Dutch mestizo x zebu, with an average age of 12 months were dewormed with an anthelmintic. Next, 20 days ...
Tópico(s): Rabbits: Nutrition, Reproduction, Health
2017 - Taylor & Francis | Biocontrol Science and Technology

Cleine Aglacy Nunes Miranda, Érika Galvão Lima, Diego Breno Soares de Lima, Ricardo Ney Cobucci, Maria da Conceição de Mesquita Cornetta, Thales Allyrio Araújo de Medeiros Fernandes, Paulo Roberto Medeiros de Azevedo, Jenner Chrystian Veríssimo de Azevedo, Josélio Maria Galvão de Araújo, José Veríssimo Fernandes,
Objective. To evaluate the prevalence of HSV-1 and HSV-2 in pregnant and nonpregnant women, testing the correlation between DNA of the viruses with colposcopic and/or cytological changes, and evaluate association with sociodemographic characteristics and sexual activity. Methods. Included in this study were 106 pregnant and 130 nonpregnant women treated at primary health care units of Natal, Brazil, in the period 2010-2011. The patients were examined by colposcopy, and two cervical specimens were ...
Tópico(s): Vector-Borne Animal Diseases
2014 - Hindawi Publishing Corporation | ISRN Obstetrics and Gynecology

Cristina Castro-Lima Vargens, Maria Fernanda Rios Grassi, Ney Boa‐Sorte, Regina Helena Rathsam-Pinheiro, Viviana Nilla Olavarria, Ramon de Almeida Kruschewsky, Bernardo Galvão‐Castro,
A high HTLV-1 proviral load is found in HTLV-1-associated diseases, mainly HAM/TSP. However, the association between proviral load and keratoconjunctivitis sicca (KCS) has not been well established. To verify the association between KCS and HTLV-1 proviral load. 104 HTLV-1 infected patients (51 asymptomatic and 52 with HAM/TSP) from the HTLV reference center in Salvador, Brazil were followed from June 2008 to May 2010. Evaluation of tear secretion was performed by BUT (break-up time), Rose Bengal and ...
Tópico(s): Vector-Borne Animal Diseases
2011 - Elsevier BV | Journal of Clinical Virology

Ney Augusto Dumont, TATIANA GALVÃO KURZ,
This paper introduces a formulation for 3D potential and linear elasticity problems that end up with the analytical handling of all regular, improper, quasi-singular, singular and hypersingular integrals of an implementation using linear triangle (T3) elements.The extension to flat Q4 and T6 elements is almost straightforward.Results at arbitrarily located internal points are also given analytically.The formulation is based on a generalized transformation to subtriangle coordinates that simplifies ...
Tópico(s): Numerical methods in engineering
2019 - WIT Press | WIT transactions on engineering sciences

José Veríssimo Fernandes, Ricardo Ney Cobucci, Carlos André Nunes Jatobá, Thales Allyrio Araújo de Medeiros Fernandes, Judson Welber Veríssimo de Azevedo, Josélio Maria Galvão de Araújo,
Epigenetic disorders such as point mutations in cellular tumor suppressor genes, DNA methylation and post-translational modifications are needed to transformation of normal cells into cancer cells. These events result in alterations in critical pathways responsible for maintaining the normal cellular homeostasis, triggering to an inflammatory response which can lead the development of cancer. The inflammatory response is a universal defense mechanism activated in response to an injury tissue, of ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2015 - Springer Science+Business Media | Pathology & Oncology Research

Daniel C. Lins, Josemberg Marins Campos, Patrícia Souza de Paula, Manoel Galvão Neto, Eduardo Pachu, Ney Cavalcanti, Álvaro Antônio Bandeira Ferraz,
Obesity and type 2 diabetes mellitus are associated to inflammatory state, which can be set off by the adipose tissue, once it is a metabolically active organ that can cause a chronic mild inflammatory state.To evaluate the correlation between preoperative C-reactive protein and postoperative complications risk in obese patients (grades II and III) after Roux-en-Y gastric bypass, with and without type 2 diabetes mellitus.Between 2008 and 2013 were analysed 209 patients (107 with diabetes), presenting ...
Tópico(s): Diet and metabolism studies
2015 - Colégio Brasileiro de Cirurgia Digestiva | ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

Camila Cristina Guimarães Nobre, Josélio Maria Galvão de Araújo, Thales Allyrio Araújo de Medeiros Fernandes, Ricardo Ney Cobucci, Daniel Carlos Ferreira Lanza, Vânia Sousa Andrade, José Veríssimo Fernandes,
Macrophage migration inhibitory factor (MIF) emerged in recent years as an important inflammation mediator, playing a prominent role in the pathogenesis of various types of malignant neoplasm. MIF is a glycoprotein that presents a wide spectrum of biological activities and exerts a complex interaction with various cellular signaling pathways, causing imbalance of homeostasis. Experimental and clinical studies show that high levels of MIF are found in almost all types of human cancers and are implicated ...
Tópico(s): Nuclear Receptors and Signaling
2016 - Springer Science+Business Media | Pathology & Oncology Research

David da Costa Nunes, Ney Boa‐Sorte, Maria Fernanda Rios Grassi, Graham P. Taylor, Maria Glória Teixeira, Maurício L. Barreto, Inês Dourado, Bernardo Galvão‐Castro,
Salvador is the city with the highest number of HTLV-1 infected individuals in Brazil, yet the main route of HTLV-1 transmission is unknown.To investigate the association of syphilis infection as a proxy for sexual transmission of HTLV-1 infection in the general population of this city.A cross sectional population-based study was conducted with 3,451 serum samples obtained by a representative simple random sampling. Data on gender, age, income, and years of education were collected by questionnaire ...
Tópico(s): Animal Disease Management and Epidemiology
2017 - Public Library of Science | PLoS ONE

Dayse Cury, Ney Boa‐Sorte, Isa Menezes Lyra, Ângela Zanette, Humberto Castro‐Lima, Bernardo Galvão‐Castro, Marilda de Souza Gonçalves,
OBJETIVO: O presente estudo teve como objetivo descrever as alterações oculares em pacientes portadores de doença falciforme, na Bahia, um estado do Nordeste, que tem a maior prevalência da doença no Brasil. MÉTODOS: Nós conduzimos um estudo de corte transversal em um grupo de 146 (292 olhos) pacientes com Doença Falciforme (90 HBSS e 56 HBSC). Para exame oftalmológico foi realizada oftalmoscopia binocular indireta complementada pela retinografia fluorescente para detecção de lesões retinianas decorrentes ...
Tópico(s): Iron Metabolism and Disorders
2010 - Sociedade Brasileira de Oftalmologia | Revista Brasileira de Oftalmologia

Ana Verena Galvão-Phileto, Ney Boa‐Sorte, Ramon A Kruschewsky, Bernardo Galvão‐Castro,
Material and methods A cross-sectional study was carried out from March to November, 2009 in Salvador, Brazil. The instruments used were a questionnaire for the collection of clinical and epidemiological data, the Mini International Neuropsychiatric Interview, Brazilian Version 5.0.0 (M.I.N.I.) to estimate the rate of depression and the short version of the WHO quality of life scale (WHOQOL-BREF).
Tópico(s): T-cell and Retrovirus Studies
2011 - BioMed Central | Retrovirology
Gílson Soares Feitosa, José Carlos Nicolau, Adalberto Menezes Lorga, Adalberto Lorga Filho, André d’Ávila, Anis Rassi, Ângelo A. V. de Paola, Anísio Pedrosa, Álvaro Barros da Costa, Ayrton Peres, César Grupi, Cláudio Cirenza, Dalmo Antônio Ribeiro Moreira, Dário Celestino Sobral Filho, Denise Hachul, Eduardo D'Andréa, Eduardo Sosa, Epotamênides Maria Good God, Fábio Sândoli de Brito, Fernando Cruz, Guilherme Fenelon, Gustavo Glotz de Lima, Hélio Brito, Ivan G. Maia, Jacob Atié, José Carlos Moura Jorge, José Carlos de Andrade, José Carlos Pachón Mateos, José Carlos Ribeiro, João Paulo Pimenta, José Tarcísio de Vasconcelos, Júlio César Gizzi, Leandro Ioschpe Zimerman, Luiz Antonio Teno Castilho, Márcio Fagundes, Márcio Jansen de Oliveira Figueiredo, Martino Martinelli Filho, Maurício Scanavacca, Ney Valente, Paulo Medeiros, Paulo Slud Brofman, Reynaldo Castro Miranda, Roberto Costa, Ricardo Kunyioshi, Roberto Novaes de Sá, Sérgio Gabriel Rassi, Sérgio Siqueira, Silas Galvão, Silvana Nishioka, Tereza Grillo, Thiago da Rocha Rodrigues, Washington Maciel,
to hemodinâmico, é fundamental na indicação do método e no sucesso da investigação [14][15][16] .Os sintomas relacionados a fatores desencadeantes deverão ser avaliados sob a ação desses estímulos.Quando os sintomas forem severos, colocando em risco a vida do paciente, deverão ser investigados em regime de internação hospitalar.
Tópico(s): Cardiac pacing and defibrillation studies
2002 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia

Regina Helena Rathsam-Pinheiro, Ney Boa‐Sorte, Maria Fernanda Rios Grassi, Úrsula Cury Copello, Karla Tayrine Silva Guimarães Rios, Théssika Hialla Almeida Araújo, Bernardo Galvão–Castro,
The prevalence of keratoconjunctivitis sicca (KCS) associated with Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) (HTLV-1/KCS) has been estimated at around 37%, but its clinical manifestations are poorly described.To determine the prevalence and associated factors of HTLV-1/KCS in a large cohort of HTLV-1-infected individuals living in Salvador, Brazil.A cross-sectional study was conducted between June 2004 and September 2017 at the Integrative and Multidisciplinary Center for HTLV in Salvador, Bahia- ...
Tópico(s): Animal Disease Management and Epidemiology
2019 - Elsevier BV | The Brazilian Journal of Infectious Diseases

Carolina Rosadas, K. Senna, Milene da Costa, Tatiane Assone, Jorge Casseb, Youko Nukui, Lucy Cook, Lívia Mariano, Bernardo Galvão‐Castro, Maria Fernanda Rios Grassi, Augusto César Penalva de Oliveira, Adele Caterino-de-Araújo, Bassit Malik, Ney Boa‐Sorte, Paula Peixoto, Marzia Puccioni-Sohler, Marisa Santos, Graham P. Taylor,
Background Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that causes severe diseases, such as aggressive cancer or progressive neurological disease.HTLV-1 affects mainly people in areas with low human development index and can be transmitted from mother to child, primarily through breastfeeding.Refraining from breastfeeding is an effective intervention to reduce the risk of infection in infants.However, HTLV-1 antenatal screening is not offered globally.According to WHO, the scarcity ...
Tópico(s): Animal Disease Management and Epidemiology
2023 - Elsevier BV | The Lancet Global Health
Tópico(s): Brazilian Legal Issues
1964 - Fundacao Getulio Varagas | Revista de Direito Administrativo

Caroline Landim, Cristiane Maria Carvalho Costa Dias, Celso Nascimento de Almeida, Ana Lúcia Barbosa Góes, Théssika Hialla Almeida Araújo, Adriele Ribeiro, Francisco Tiago Oliveira de Oliveira, Humberto Castro‐Lima, Ney Boa‐Sorte, Bernardo Galvão‐Castro,
Flexibility is crucial to the harmonious execution of joint movements. While skeletal muscle dysfunction in patients with HTLV-1 can interfere with mobility, it is unclear whether these patients experience reduced flexibility.To evaluate the differences in flexibility between HTLV-1-infected individuals with and without myelopathy compared with uninfected controls. We also investigated whether age, sex, body mass index (BMI), physical activity level, or lower back pain influence flexibility in HTLV- ...
Tópico(s): Fibromyalgia and Chronic Fatigue Syndrome Research
2023 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria