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Primary Document Acesso aberto

Jacobus Philippus, Bergomensis,

Title-vignette. Place of publication, printer's statement and date of imprint from colophon. Attributed to Jacobus Philippus. Book.

0000 - Gale Group | Sabin backfiles 2011

Artigo Acesso aberto Revisado por pares

Tito Cavallo, K Graves, Nancy L. Cole, Thomas Albrecht,

... development and maturation of cytomegalovirus (CMV) nuclear inclusions (NIs) in human embryo thyroid cells at 1 to ... from an initial fibroblastic appearance and contained early NIs. At 24 h, early NIs were larger and better defined. At 48 h, although early NIs were still present, most cells had larger and presumably more mature NIs. These latter NIs consisted of several subunits, each made up of ... At 72 h, in cells with more developed NIs, virus particles were closely associated with the fibrillar network. Between 96 and 144 h, the NIs reached maximum size and were made up of ...

Tópico(s): RNA regulation and disease

1981 - Microbiology Society | Journal of General Virology

Artigo Revisado por pares

Kyung‐Ho Jung, Jin-Young Paik, You La Lee, Yong Jin Lee, Jaetae Lee, Kyung-Han Lee,

Cell preparation procedures injurious to Na/I symporters (NIS) could deter their usefulness for reporter gene assays ... 125)I transport was evaluated using Huh-7/NIS hepatoma cells. The effects of graded concentrations of trypsin and EDTA were assessed on Huh-7/NIS and A431/NIS lung cancer cells. Trypsin-induced NIS proteolysis was investigated by immunoblots of plasma membrane ... and 4 h following administration of Huh-7/NIS cells collected with and without trypsin.(125)I Transport ability of Huh-7/NIS cells was severely impaired within minutes of standard ...

Tópico(s): Ion channel regulation and function

2009 - Elsevier BV | Nuclear Medicine and Biology

Carta Acesso aberto Revisado por pares

Lorri A. Lee, Robert C. Morell,

... second group to use the Nationwide Inpatient Sample (NIS) to determine the prevalence of POVL and its ... groups than did Patil et al.5 The NIS collects data from more than 1000 randomly selected, ... approximately 90% of all US hospital discharges. The NIS is one of many databases that are under ... centralized national information resource on patient care. The NIS was created in 1988 and contains more than ... 4 and Patil et al.5 used the NIS to examine associations with POVL and acknowledge many ... is an association, the process by which the NIS data are collected and entered into the database ...

Tópico(s): Anesthesia and Pain Management

2009 - Lippincott Williams & Wilkins | Anesthesia & Analgesia

Primary Document Acesso aberto

Vespucci, Amerigo, Giocondo, Giovanni,

Title from caption. Collation of original: 4 leaves (Recto of second and fourth leaves paged in ms. 3 and 7 respectively). Black letter. Forty-four lines ...

0000 - Gale Group | Sabin Jan-Jun 2013

Artigo Acesso aberto Revisado por pares

Elizabeth G. Nabel,

... 3We were interested in knowing more about the NIs who have received funding since 2005. We analyzed ... data on the basis of the following definitions. NIs who are within 10 years of completing their ... residency are designated Early Stage Investigators (ESIs), and NIs who are >10 years from their terminal degree ... non-ESIs. To our surprise, only 55% of NIs were ESIs. The remaining 45% were established investigators ... in FY 2009.4 The career stage of NIs will be taken into account when their grant ... to select the same proportion of applications from NIs, including ESIs, as from established investigators for discussion ...

Tópico(s): Health Sciences Research and Education

2009 - Lippincott Williams & Wilkins | Circulation

Jornais Acesso aberto

Dr Mike Fitzpatrick, Lea Paterson and Clive Mathieson, Cath Urquhart, Stella Shamoon, Richard Whitehead, Portia Colwell, Robert Cole, Anee Ashworth, Catherine Riley, Andrew Pierce, Adam Sherwin Media Reporter, Maggie Alderson, Jane MacQuitty, Simon Barnes, Michael CROUGH(Senior Academic Principal), Jasper Rees, Kate Perera, Robert Thicknesse, SD, Richard Smart, Mark Souster, Pauline Caddick, Richard Hobson, Jonathan Lennie, Michael Evans Defence Editor, Philip Howard, Ian Cobain, Hilary Finch, Lucy Elkins, Maggie Philbin, James Bone, Andy Stephens Football Flutter, Edna Read Neal, Edward Welsh, David Atkinson, John Bungey, Sue Connolly Sports Picture Editor, Credo Stephen Plant, Clare Stewart, Giles Coren, John O'Leary Education Editor, Douglas Rushkoff, Andrew Norfolk and Stewart Tendler, Carl Evans, Antonia Senior, Ian Cobain and Michael Binyon, András Schiff/Matthias Goerne, Peter V. Facey, David McVay, Stephen McClarence, Michael Halpern, Nigel Havers, Hilary Rose, Conal Urquhart, Vinny Lee, Katherine Swift, Dominic Walsh, Ben Christophers Singer-Songwriter, Julie Christie, Trevor LLOYD-HUGHES(Press Secretary to the Prime Minister), Bobby Robson, Jill Dupleix, Grainne Gilmore, Michael Harvey, Martin Barrow, Dalya Alberge Arts Correspondent, Peter Richardson, Michael Mulvihill, Candida Crewe, Jo Morris, Alan Hamilton, Robin Young, Nicholas Roe, Simon Cowell, Jan Raath and Sam Coates, Anthony G. Phillips, Peter Nichols, William Gay, Roland Watson, David Hands, Alex Knisely, Martin Symington, Bryan Storey, Clive Mathieson Telecoms Correspondent, Caroline Merrell Banking Correspondent, Mark Court, Derwent May, Angela Jameson, Kate Muir, Zorro Sidloyi, Paula Hawkins, Alexander Smith, Mary Gold, Oliver Kay, Claire Bowman, Amber Cowan, Stephen Anderton, Mark Atherton, Jane Wheatley, Brenda Polan, Michael Theodoulou, Rick Broadbent, Christopher Meakin, Liz Bird, Sam Coates, John Hopkins, Rob Wright, David Beckham, Sarah Turner, Declan Weir, Alf Hailstone, Mark Dornford, Adam Sage, Matthew Pryor, Cheryl Taylor, Paula George, 33, captain of England rugby team, Lucy Pinney, John McCabe, James Allcock, Christine Buckley Industrial Editor, Peter Stothard, Robin Young and James Doran, Greg Hurst Parliamentary Correspondent, Henry PAVLOVICH(Director and Chief Executive), Dominic Streatfield, John S. Mercer, Cathy Harris, Helen Nugent, Michael Strutt, Damian Whitworth, Chris Ayres and Dominic Walsh, Mick Hume, Will Carling, Emily Davies, Nick Hasell, Tom Baldwin and Philip Webster, Patricia Furley, Graham Searjeant Personal Investor, Alison Kervin Chief Sports Feature Writer, David Hands Rugby Correspondent, James Collard, Adam Fresco, Steve Jelbert, Louise Branson, Nick Szczepanik, John Goodbody, Jack Crossley, Michael Evans Defence Editor and Roland Watson, Dearbáil Jordan, James Doran, Philip Webster Political Editor, Christopher Walker, Robert Crampton, Fontham Meades, Mike Brewer, Kevin McCarra, Matthew Parris, Graham Searjeant Financial Editor, Angus Clarke, Sue Hepworth, Chris McGrath, Terence Crolley, Doug McKinlay, Russell Jenkins, Clarissa Hyman, Alan Lee, Amber Cowan's, Jane Owen, John Angerson, DC, Ben MacIntyre, Christopher Reed, Alison Gibson, Richard Miles, John Naish, Simon Jenkins, Annabelle Thorpe, Toby Litt, Gary Duncan Economics Correspondent, Mark Henderson, Martin Waller, Michael Horsnell, Chris Ayres, David M. Howell, Danny Baker, Carl Mortished International Business Editor, Nigel Hawkes Health Editor, Laura Peek, Benedict Nightingale, Stephen Dalton, Jill Crawshaw, Hugh Thompson, Nicholas Page, David Powell, Tom Chesshyre, Valerie Grove, Jamie Oliver, Michael Evans, Fiona Beckett, Edward Gorman Sailing Correspondent, Paula George's and Miss Abigail, Bill McLaren, Patience Wheatcroft, Peter Blaker, Christopher Irvine, Susan Emmett, David Lister Ireland Correspondent,

... 10", blue eyes,… Good-Looking male, 36,6', Nis many varled… How anyone at any age can ...

2002 - Gale Group | TDA

Artigo Revisado por pares

Kathrin Klutz, Verena Ruß, Michael J. Willhauck, Nathalie Wunderlich, Christian Zach, Franz Josef Gildehaus, Burkhard Göke, Ernst Wagner, Manfred Ogris, Christine Spitzweg,

... mouse models following transcriptionally targeted sodium iodide symporter (NIS) gene transfer. These studies showed the high potential of NIS as a novel diagnostic and therapeutic gene for ... a next crucial step towards clinical application of NIS-mediated radionuclide therapy we aim at systemic delivery of the NIS gene to target extrathyroidal tumors even in the ... tumor affinity (G2-HD-OEI) to target a NIS-expressing plasmid (CMV-NIS-pcDNA3) to neuroblastoma (Neuro2A) cells. Results: Incubation with NIS-containing polyplexes (G2-HD-OEI/NIS) resulted in ...

Tópico(s): Cancer Research and Treatments

2009 - American Association for Cancer Research | Clinical Cancer Research

Primary Document Acesso aberto

Cajetan, Tommaso de Vio,

... m]pressioni dedit expensis honesti viri Joa[n]nis Petit ... anno d[omi]ni 1511, 3 nonas ...

0000 - Gale Group | The Making of Modern World

Artigo Acesso aberto Revisado por pares

Charlotta Lundh, Ulrika Lindencrona, Per Postgård, Therese Carlsson, Mikael Nilsson, Eva Forssell‐Aronsson,

... downregulating the expression of the sodium iodide symporter (NIS). The rationale for this study was therefore to study effects on iodide transport and NIS messenger RNA (mRNA) expression in thyrocytes exposed to ... or 211 At, all being radionuclides transported via NIS, in the culture medium for 6 h, or ... 123 I or 131 I for 48 h. NIS mRNA expression was analyzed using quantitative reverse-transcriptase polymerase chain reaction. Results: Iodide transport and NIS mRNA expression were reduced by all radionuclides. At ...

Tópico(s): Radiation Dose and Imaging

2009 - Society of Nuclear Medicine and Molecular Imaging | Journal of Nuclear Medicine

Jornais Acesso aberto

Giles Smith, Andrew Robson, Joanna Hines, Gary Jacob and Russell Kempson, Roger Boyes and Anthony Browne, Carol Lewis, Peter Sainsbury, Robert Cole, Adam Sherwin Media Reporter, Alan King-Hamilton, Greg Hurst Political Correspondent, Frances Gibb Legal Editor, Simon Barnes, Christopher Wood, Mark Souster, Jim Newman, Anthony Lloyd, Ivo Tennant, Philip Howard, Hannah Betts, Christine Seib, David Chater, Rachel Campbell-Johnston, James Bone, Nic Hopkins, Maxim Jakubowski, Clive Davis, Alexandra Frean Social Affairs Correspondent, Richard Hobson One-Day Cricket Correspondent, Elizabeth Judge, Richard Irving, Sam Marlowe, Wendy Ide, Jim Cowley, Kevin Eason, Nick Hasell Stock Markets, Daniel McGrory and Richard Ford, Ben Webster Transport Correspondent, Pat Gibson, Valerie Elliott Countryside Editor, Daniel McGrory and Michael Evans, Dominic Walsh, Tom Bawden, James Doran Wall Street Correspondent, B. M. Boyd, Debra Craine, Angela Jameson Industrial Correspondent, Ruth Gledhill Religion Correspondent, Phoebe Greenwood, Richard Ford Home Correspondent, David Dover, Alan Hamilton, Gabriel Rozenberg and Patrick Hosking, Anatole Kaletsky, Christopher Mayer, Roland Watson, Dominic Walsh and Jenny Davey, Charles Bremner, Ian Newbery, Robert Smith, Russell Kempson, Lauren Goldstein Crowe, L. J. Jones, Oliver Kay, Gerard Baker, Martin Johnson, John Westerby, Neil Harman, Patrick Hosking Investment Editor, Tom Baldwin, Ann Treneman, Simon de Bruxelles, Geoffrey Dean, Mark Hunter, Neil Harman Tennis Correspondent, David Powell Athletics Correspondent, Boris Becker, Raymond Keene, Michelle Henery Enterprise, Sean MacAulay, Bryan Owram, David Willetts, Rosemary Bennett Deputy Political Editor, Helen Rumbelow and Charles Bremner, Marc Aspland, Caroline Merrell, Chris Campling, Bronwen Maddox, Carolina Merrell Banking Correspondent, Patrick Hosking, Richard Owen, Shane Warne, Rick Breadbent, Richard Mills, David Hands Rugby Correspondent, Kevin Maher, Julian Muscat, John Kennedy, Alan Lee Racing Journalist of the Year, Mike Sackett, James Doran, Philip Webster Political Editor, Tosin Sulaiman, John Trowell, Peter Klinger and Rory Watson, Ian Johns, Des Dearlove, Ashling O'connor, L. L. Blake, Esther Walker, Neil Fisher, Michael Austin, Peter Riddell, Ben MacIntyre, Steven Levitt, Tony Dawe, Carly Chynoweth, Susie Symes, Mark Henderson, Martin Waller, Michael Horsnell, Chris Ayres, Carl Mortished International Business Editor, Richard Horton, Mark Baldwin, Ashling O'Connor, Dr Thomas Stuttaford, Stephen Dalton, Alexandra Frean and Toain Sulaiman, Leo Lewis, Richard Morrison, James Christopher, Jenny Davey, A. Morgan, Peter Klinger, Sam Lister Health Correspondent, Patience Wheatcroft, Nick Meo, Joe Bolger, Ross Anderson, Elizabeth Judge Telecoms Correspondent, Simon Farrell, Barbara Lawrence,

... Police remove ten speed cameras over safety fears NIS Nature British troops to Afganistan Blair apologises to ...

2005 - Gale Group | TDA

Artigo Revisado por pares

Joon‐Kee Yoon, Bok-Nam Park, Jin-Young Paik, Kyung‐Ho Jung, Bong-Ho Ko, Kyung-Han Lee,

... 7 cells that express endogenous sodium/iodide symporter (NIS) and SNU-C5 cells adenovirally transduced with the human NIS gene (SNU-C5/NIS) were treated with 10−7–2 × 10−4 ... and then, radioiodide uptake and retention were measured. NIS expression was assessed by immunohistochemistry and Western blot analysis, using an antihuman NIS monoclonal antibody. Results: Theophylline at 10−6–2 × ... 6–10−5 mol/L in SNU-C5/NIS cells, without affecting radioiodide efflux. Abrogation by KClO4− ... iodide transport. Immunohistochemistry revealed dose-dependent increases of NIS staining in MCF-7 and SNU-C5/NIS ...

Tópico(s): Renal and related cancers

2009 - Mary Ann Liebert, Inc. | Cancer Biotherapy and Radiopharmaceuticals

Jornais Acesso aberto

Jacquey Visick, Waldemar Januszczak, John Dugdale, Michael Prescott, Pete Bradley, Katerini, Mary Anne Fitzgerald, Alexander Goehr, Barbara Hall, Richard Ellis, Judge Stephen Tumim, Peter McKay, I Rauta, John Davison, Norman Rose, Judith Baron, Geoffrey Giuliano, John Peter, Fraser Marr, Mark Reason, John Harlow Transport Correspondent, Jonathan Miller, Eric Dymock, Norman MacRae, Julie Cohen Education Reporter, Colm Halloran, A M Cassandre, Susan d'Arcy, Janice Broxup, Graham Rose, Sheridan Morley, George Charlton, Christa D'souza, Mike Watkinson, Sally Payne, Lucy Hughes-Hallett, David Smith, Sydney Waissel, Adam Nicolson, Nomavenida Mathiane, David Schwartz, Ahmed Rashid, Alysen Miller, Mary Wilson, Linda Davies, Graeme Jardin, Geordie Greig, Tony Allen-Mills, Neville Hodgkinson, Martin James, Robert Sandall, Iain Johnstone, Boris Yeltsin, Nilgin Yusuf, Irwin Stelzer, Robert Hewison, Ivan Fallon, Peter Wilson, Deryk Brown, David Dougill, John Mortimer, Rev D J Brecknell, Mariella Frostrup, Mark Vandevelde, Makbool Javaid, Harvey Porlock, Captain Peter Collinson, Margarette Driscoll, Hugh Mcllvanney, Leon Simons, Jeremy Clarkson, Richard Sharman, Louise Taylor, David Coleman, David Lloyd, Chris Dodd, Geoff Whitten, John Taylor, Andrew Varley, Caroline Lees, Goldman Sachs, Pauline Bousquet, Ranulph Fiennes, Jane Urquhart, Peter Kellner, Liz Jones, George Perry, Sue Mott, Glyn Maxwell, Peter Cole, Nick Gardner, Christine Klein-Braley Senior Lecturer, Shelley von Strunckel, Stewart Roberts, Ardyn Bernoth, Jonathan Margolis, Rob Steen, Bernard Cafferty, Stuart Wavell, Maggie Gee, Paul Donovan, Emma Robertson, Peter Lewis, Sue Lawrence, Mary Loudon, Jeff Randall, Harry Lovelock, Lisa Jardine, Finstat, James Bethell, Paul Driver, James Adams, N Marshall, Liz Lightfoot, Ian Chadband, Richard Bath, David Leppard, Tim Rayment, Peter Plant, A White, Mark Edwards, Kirstie Hamilton, Fiona Lafferty, Rufus Olins, Chris Gilchrist, Gerry Howard Chief Organiser, David Lawrenson, Nigel Bowden, Corinne Coleman, Dave Thomas, Ian Hodge, Charles Hymas Education Correspondent, Christopher Lloyd, B Hall, David Woods, Sean Newsom, Christa D'Sonza, John Karter, Kate Saunders, Barbara Amiel, Malcolm Winton, Stanley Stewart, Marie Colvin, Claire Galea, Kipper Williams, Craig Brown, Norman Parkinson, Michael Bell, Los Angeles, Stephen Jones, Paul Nuki Deputy Personal Finance Editor, M Dennett, Andrew Grice Chief Political Correspondent, Paul Zeal, Paul Nuki, Andrew Grice, Susan Howatch, Sally Soames, Martin Searby, Keith Wheatley, Claire Oldfield, Christine Toomey Colon, Nell MacLean, Anthony Fraser, Martin Keatman, Ian Burrell, Liz Brooks, Andrew Lorenz Associate Business Editor, Bernard Fitzsimons, Graham Phillips, G R Hughes, E A Henderson, Richard Woods, Clive Everton, Garth Alexander, Roland White, Peter Johnson, Rachel Cooke, Antony Worrall Thompson, Mark Dampier, David Churchill, Kevin Pratt, Roger Lewis, Julie Burchill, Dr L Hill, J L Ginnerver, David Hunn, D J Taylor, Mihir Bose, Jonathan Rendall, John Harlow, Matthew Lynn, Michael Austin, Neil A Stevens, Robert Frost, Humphrey Burton, Andrew Alderson, John Waples, McEnroe, A A Gill, Andrew Malone, Matthew Campbell, Stan Levenson, W Midlands, John Carey, Norman Macrae, Chris Dighton, Peter Wilkinson, Adrian Dannatt, Anna Pukas, Alex Spillus, Gilbert Adair, Andrew Lorenz, Sean O'brien, Liam Clarke, David Wickers, Alan Ruddock, Bramall Lane, Elizabeth Buchan, Nigel Roebuck, Chris Lightbown, Vince Wright, Jeff Randall City Editor, Richard Caseby, Tom Hiney, Rupert Sheldrake, Hugh Pearman, Penny Perrick, Susan Ellicott, Tony Hetherington, Anthony Howard, Emma Forrest, Peter Roebuck, Walter Ellis, Stephen Boyd, Joanna Simon, Steve Grant, Chris Brasher, Lynn Barber, Pete Anderson, Dominic Rushe, Sarah Alexander, Boris Schapiro,

... MacLed Talisman Group of Companies Ltd North Warwickshire Nis Trust Charterhouse Executives JP Morgan Fletcher Hunt PLC ...

1994 - Gale Group | Sunday Times HA GDA

Revisão Revisado por pares

Cornelia Schmutzler, Josef Köhrle,

The recently cloned sodium-iodide symporter (NIS) represents a key molecule for thyroid function by efficiently accumulating iodide from the circulation into the thyrocyte against an electrochemical gradient. This ... TSH, the main hormone regulating thyroid-specific functions. NIS mutations are found in congenital hypothyroidism, and potential defects in the NIS gene, its expression, or function of the NIS protein are currently under investigation in various thyroid diseases. Increased NIS expression has been found in autonomous adenoma and ...

Tópico(s): Thyroid Cancer Diagnosis and Treatment

2009 - Thieme Medical Publishers (Germany) | Experimental and Clinical Endocrinology & Diabetes

Jornais Acesso aberto

Anthony Harris, Nicholas Hinton President and Chief Executive, Jon Ashworth, Andrew Pierce, Political Correspondent, Martin Baker, Philip Ziegler, Iain R. Webb, George Guise (Prime Miniser's Policy Unit), Dan McGrory, Jeremy Laurance and David Charter, Adrian Lee, Richard Ford, Home Correspondent, Philip Webster and James Landale, Robert Vincent, Magnus Linklater, Richard Thomson, Inigo Gilmore, Alan Hamilton and Valerie Elliott, Harvey Elliott, Richard Hobson, Philip Howard, Carol Midgley, Jeremy Kingston, James Bone, Nigel Harris, Clive Davis, Dominique Searle and Michael Evans, Defence Correspondent, Carl Mortished, Morag Preston, Nigel L. Denton, Simon Wilde, Roger Maynard, Stewart Tendler, Crime Correspondent, Christine Buckley Industrial Correspondent, Mike Carter, Patrick Moore, Clare Stewart, Robert Sheehan, Bridge Correspondent, Peter Brown, Jonathan Prynn, Transport Correspondent, Mike Horsnell, Joanna Bale and Bill Frost, Ivor Davies, Peter Ball, Shirley English, Raymond Keene Chess Correspondent, Rachel Kelly, Ross Dunn, John H. Lamb, Ruth Gledhill Religion Correspondent, Stephen Farrell, N. Grewal, Amanda Loose, Jeremy Laurance, Health Correspondent, John Young, Nigella Lawson, Robert Miller Banking Correspondent, Brian Grove, Russell Jenkins and Marcus Binney, Harvey Elliott, Air Correspondent, Nigel Williamson, Stuart Sanders, Nigel Hawkes and Quentin Letts, Belinda Archer, Lin Jenkins, James Wood (National Chairman), Barry Millington, Arthur Leathley, Political Correspondent, Raymond Keene, Peter Davalle, Alan Lee, Cricket Correspondent, Jonathan Prynn Transport Correspondent, Alix Ramsay, Paul Wilkinson, P. H. S, Paul Griffiths, Chris Lockwood, Nigel Hawkes, Bronwen Maddox, Jill Sherman, Eric Reguly, Richard Owen, Oliver Holt, Damian Whitworth, Adrian Rogers, Janet Bush and Clare Stewart, Roger Boyes, Sarah Cunningham, Oliver August, Andrew Pierce Political Correspondent, David Hands Rugby Correspondent, Julian Muscat, Richard Duce, Ian Murray, Community Correspondent, Christopher Thomas, Anne Ashworth, David Churchill, Guy Walters, Philip Webster Political Editor, Iola Smith, Rob Hughes, Football Correspondent, Christopher Walker, Julia Lewis, Paul Nathanson, Jason Nissé, Kathryn Knight, Gerald Larner, Peter Riddell, Ben MacIntyre, Tony Dawe, Richard Beeston, John Spiers Chairman, Jennifer Wood, Tim Jones, Michael Evans Defence Correspondent and our Foreign Staff, A. J. Lucking, Nigel Hawkes Science Editor, Alan Coren, Rachel Bridge and Alasdair Murray, Benedict Nightingale, Jon Ashworth and Robert Bruce, Tom Rhodes, Marianne Curphey, James Landale and Dominique Searle, Richard Morrison, George Edwards, David Maddock, A. G. Alexander, Christine Buckley, Industrial Correspondent, John Watson,

... award judges media portrayal of the disabled, Jason Nis reports F Foxtons North of the Thames Multiple ...

1996 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Emi Ohashi, Takahiko Kogai, Hiroyuki Kagechika, Gregory A. Brent,

... breast is mediated by the sodium/iodide symporter (NIS). NIS activation is used for radioiodide imaging and therapeutic ablation of thyroid carcinoma. NIS is expressed in >70% of breast cancers ... radioiodine treatment. All-trans retinoic acid (tRA) induces NIS gene expression and functional iodide uptake in human ... PI3K) signal transduction pathway that mediates tRA-induced NIS expression in MCF-7 breast cancer cells. MCF- ... previously identified RARβ and RXRα as important for NIS induction by tRA. Treatment with LY294002, the PI3K ...

Tópico(s): Thyroid Disorders and Treatments

2009 - American Association for Cancer Research | Cancer Research

Periodico

OECD iLibrary

Jornais Acesso aberto

By Julian Haviland, Political Editor, By Our Political Editor, By Paul Routledge, Labour Editor, By Rupert Morris, Michael Hornsby, By Derek Harris, Commercial Editor, By David Walker, From Roger Boyes, By Hugh Clayton, Environment Correspondent, By Peter Evans, Home Affairs Correspondent, By Donald Macintyre, David Hewson, By Alan Hamilton, From Harry Golombek, Chess Correspondent, By Anthony Bevins Political Correspondent, By Geraldine Norman, Sale Room Correspondent, By Michael Baily Transport Editor, By Christopher Warman Arts Correspondent, By Anthony Bevins, Political Correspondent, From Michael Hamlyn, By Nicholas Timmins, By David Hewson, From Arthur Osman, By Kenneth Gosling, By Frances Williams Economics Correspondent, By Rodney Cowton Defence Correspondent, By Peter Evans Home Affairs Correspondent, By Frances Gibb, Legal Affairs Correspondent, From Christopher Follett, From Ian Murray, From George Clark, From Dianal Geddes, From Richard Owen, From Nicholas Ashford, From Stephen Taylor, From Zoriana Pysariwsky, From Michael Hornsby, From Andrew Thompson, From Neil Kelly, Trevor Fishlock, Olivia Timbs, Lorraine Fraser, By Henry Stanhope, Diplomatic Correspondent, From Jacqueline Reditt, PHS, Paul Routledge Labour Editor, David Watt, Philip Howard, TREVOR WEST, DAVID MORRISON, DONALD TEBBIT, TOM CROSS, CHRISTOPHER BLISS, DAVID SERPELL, F. M. M. STEINER, CLIVE THOMAS, KATHRYN DAVIS, LESLIE F. CURTIS, JAMES RUSBRIDGER, GRAHAM ZELLICK, NIGEL SAUL, M. A. CLARK., Edward Mortimer, Robert Bailey, RB, Penelope Turing, Peter Ackroyd, David Robinson, John Percival, Ned Chaillet, Nicholas Kenyon, Stephen Pettitt, John Gill, City Editor Anthony Hilton, By Our Financial Staff, Sally White, By Sally White, By Frances Williams, Economics Correspondent, By Jonathan Clare, By Our Economics Correspondent, By Our Banking Correspondent, By Peter Wilson-Smith Banking Correspondent, By Bill Johnstone Electronics Correspondent, Michael Clark, Jeremy Warner, C. Gordon Tether, By Stuart Jones, Football Correspondent, By Peter Ball, From Athole Still, By Paul Newman, By Clive White, By Pamela Macgregor-Morris, From Bryan John, From John Woodcock, Cricket Correspondent, Hobart, From Sydney Friskin, By a Special Correspondent, By Derek Wyatt, By Gerald Davies, By Michael Seely, By Joyce Whitehead, By Keith Macklin, BY Our Racing Staff, Motoring by Clifford Webb, Edited by Peter Lee, By Edward Mortimer, By Rodney Cowton, Defence Correspondent,

... Money Markets, MPs urge priority for cut in NIS, Company News In Brief, Reed shares down 8p ...

1982 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Florian Gaertner, Franziska Rohde, Jan Mueller, Birgit Blechert, Klaus–Peter Janssen, Markus Essler,

Abstract The sodium iodide symporter (NIS) mediates iodide uptake into the thyroid. Because of this mechanism, differentiated thyroid cancer is susceptible for radioiodine therapy. Functional NIS expression in extrathyroidal tumors has been reported mainly in breast cancer. We screened colorectal tumors for NIS expression and investigated the mechanisms regulating NIS activity. Cell lines were screened for iodide uptake in vitro and NIS expression was evaluated by real‐time RT‐PCR, ... gene adenomatous‐polyposis coli (APC) were screened for NIS expression by RT‐PCR. In vitro , functional NIS ...

Tópico(s): Cancer-related Molecular Pathways

2009 - Wiley | International Journal of Cancer