... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios Duetto Nix. Musical work.
0000 - Gale Group | NCCO British Theatre
... pathways converge. In addition, the BNip3-related protein, Nix/BNip3L, has recently been shown to play an ... group of BH3-only proteins that includes BNip3, Nix/BNip3L, and BNip3H.10 In contrast to Bid and Bad, the proapoptotic activity of BNip3 and Nix is regulated through transcriptional mechanisms that involve the ... another HIF-inducible member of the BNip3 family, Nix/BNip3L, has been shown to be upregulated during ... to hypoxia. It is likely that expression of Nix is also upregulated during hypoxia. If its activity ...
Tópico(s): ATP Synthase and ATPases Research
2002 - Lippincott Williams & Wilkins | Circulation Research
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios Pantomime "Nix". Musical work.
0000 - Gale Group | NCCO British Theatre
Efemwonkiekie W. Iyamu, Ernest Turner, Toshio Asakura,
... effects, we investigated the antisickling effect of NIPRISAN (Nix‐0699). We found that Nix‐0699, an ethanol/water extract from indigenous plants, has a strong antisickling effect. The concentration of Nix‐0699 required to inhibit 50% of erythrocyte sickling ... of polymerization, addition of 0·05 μg/ml Nix‐0699 caused a sixfold prolongation of the delay ... deoxy‐Hb S significantly increased upon treatment with Nix‐0699. Analysis of the effect of Nix‐0699 on the Hb S oxygen affinity indicated ... These results suggest that the antisickling properties of Nix‐0699 may involve direct interaction with Hb molecules. ...
Tópico(s): Erythrocyte Function and Pathophysiology
2002 - Wiley | British Journal of Haematology
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios "Score" of Pantomime "Nix". Musical ...
0000 - Gale Group | NCCO British Theatre
Kenneth Lim, Denise Pugash, Jerome Dansereau, R. Douglas Wilson,
... To determine if the ultrasound marker Nuchal Index (NIx) is gestational age independent, and to determine its ... normal karyotype or normal postnatal exam. Nuchal Index (NIx) was defined as 100x (mean nuchal thickness [mm])/( ... analysis group, Pearson coefficient and ANOVA confirm that NIx was independent of gestational age between 14 + 0 ... weeks of gestation. For the analysis group, mean NIx was 7.72, (SD = 2.05) and a ... DS fetuses made up the abnormal group. Mean NIx in this group was 17.9 (SD = 13. ... 00001) compared to the analysis group. Using an NIx threshold of 11.0, sensitivity for any DS ...
Tópico(s): Fetal and Pediatric Neurological Disorders
2002 - Wiley | Prenatal Diagnosis
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios Solo's in Ballet of ...
0000 - Gale Group | NCCO British Theatre
Keith A. Webster, Nanette H. Bishopric,
... More recently, the proapoptotic Bcl-2 family member Nix/BNIP3L (Nix) was identified as a potential downstream effector of Gαq-initiated apoptosis.10 Expression of Nix is induced in the hearts of Gαq-transgenic ... patients.10 Mice with cardiac-targeted overexpression of Nix directed by the α-MHC promoter died within ... overexpressing both Gαq and a dominant negative (truncated) Nix cDNA (sNix) were protected from pressure-overload cardiomyopathy. The identification of Nix as part of the Gαq pathway represents an ...
Tópico(s): Protein Kinase Regulation and GTPase Signaling
2003 - Lippincott Williams & Wilkins | Circulation
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios Musical work.
0000 - Gale Group | NCCO British Theatre
Abhinav Diwan, Scot J. Matkovich, Qunying Yuan, Wen Zhao, Atsuko Yatani, Joan Heller Brown, Jeffery D. Molkentin, Evangelia G. Kranias, Gerald W. Dorn,
Transcriptional upregulation of the proapoptotic BCL2 family protein NIX limits red blood cell formation and can cause ... poorly defined. Here, we show complementary mechanisms for NIX-mediated cell death involving direct and ER/sarcoplasmic ... mediated (ER/SR-mediated) mitochondria disruption. Endogenous cardiac NIX and recombinant NIX localize both to the mitochondria and to the ... stores are proportional to the level of expressed NIX. Whereas Nix ablation was protective in a mouse model of ... correction of the decreased SR calcium content of Nix-null mice restored sensitivity to cell death and ...
Tópico(s): Autophagy in Disease and Therapy
2008 - American Society for Clinical Investigation | Journal of Clinical Investigation
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Héctor Sandoval, Perumal Thiagarajan, Swapan K. Dasgupta, Armin Schumacher, Josef T. Prchal, Min Chen, Jin Wang,
... that a member of the Bcl-2 family, Nix/Bnip3L, helps eliminate organelles by by autophagy (or 'eating') of the mitochondria. Nix−/− mice developed anaemia with reduced mature erythrocytes and ... erythroid precursors. Erythrocytes in the peripheral blood of Nix−/− mice exhibited mitochondrial retention and reduced lifespan in ... that a member of the Bcl-2 family, Nix, helps eliminate organelles by autophagy of the mitochondria. Erythrocytes in the peripheral blood of Nix−/− mice exhibited mitochondrial retention and reduced lifespan in ...
Tópico(s): Hemoglobinopathies and Related Disorders
2008 - Nature Portfolio | Nature
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Yun Chen, William Lewis, Abhinav Diwan, Emily H. Cheng, Scot J. Matkovich, Gerald W. Dorn,
... observed regulation of intracellular calcium stores by reticular Nix. Here, we report effects of Nix targeting to mitochondria or ER on cell death pathways and heart failure progression. Nix-deficient fibroblasts expressing mitochondrial-directed or ER-directed Nix mutants exhibited similar cytochrome c release, caspase activation, ... V and TUNEL labeling, and cell death. ER-Nix cells, but not mitochondrial-Nix cells, showed dissipation of mitochondrial inner membrane potential, ... implicating the mitochondrial permeability transition pore (MPTP). ER-Nix cells were not protected from death by caspase ...
Tópico(s): ATP Synthase and ATPases Research
2010 - National Academy of Sciences | Proceedings of the National Academy of Sciences
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Michael Wilhelm, Zhiheng Xu, Nickolay V. Kukekov, Stephen Gire, Lloyd A. Greene,
Nix, a pro-apoptotic BH3-only protein, promotes apoptosis of non-neuronal cells, although the mechanisms involved ... bait, we identified an interaction between POSH and Nix. Co-immunoprecipitation and in vitro binding studies confirmed a direct interaction between POSH and Nix in mammalian cells. When overexpressed in HEK293 cells, Nix promotes apoptosis along with enhanced phosphorylation/activation of ... effects appear to be dependent on POSH because Nix does not promote either JNK/c-Jun phosphorylation ...
Tópico(s): Nuclear Receptors and Signaling
2006 - Elsevier BV | Journal of Biological Chemistry
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Yuntao Lu, Leyu Wang, Minyi He, Wenhua Huang, Hong Li, Yongkui Wang, Jiming Kong, Songtao Qi, Jun Ouyang, Xiaozhong Qiu,
Previous reports indicate that the NIX/BNIP3L gene acts as a pro-apoptotic factor by interacting with BCL2 and BCL-XL, playing an important role in hypoxia- ... tumor suppressor. However, many studies also showed that NIX is linked to a protective role and cell ... activation inhibitor) expression, but a greater expression of Nix and p-NF-κB proteins in the Nix-wt U251 cells, which was not observed in the Nix-kn cells under hypoxic conditions. Using electrophoretic mobility ... of NF-κB was detected only in the Nix-wt U251 cells with hypoxia. These data imply ...
Tópico(s): Cancer-related molecular mechanisms research
2012 - Public Library of Science | PLoS ONE
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Jui‐Lee A. Birse‐Archbold, Lorraine E. Kerr, Paul A. Jones, James McCulloch, John Sharkey,
Nix, a hypoxia-sensitive member of the Bcl-2 family, is upregulated at the mRNA level during ... its promoter sequence. However, the mechanism(s) regulating Nix protein activation remain unclear. The present studies examine Nix protein expression and subcellular distribution in response to ... apoptotic stimuli in vitro. Upregulation and translocation of Nix (by day 5) in hypoxic/serum-deprived CHO- ... initiation of cell death in vitro is a Nix-independent event. In contrast, an early Nix response (upregulation and translocation to the mitochondria) was ...
Tópico(s): ATP Synthase and ATPases Research
2005 - SAGE Publishing | Journal of Cerebral Blood Flow & Metabolism
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Anita Gálvez, Eric W. Brunskill, Yehia Marreez, Bonnie J. Benner, Kelly M. Regula, Lorrie A. Kirschenbaum, Gerald W. Dorn,
Up-regulation of myocardial Nix and BNip3 is associated with apoptosis in cardiac hypertrophy and ischemia, respectively. To identify mechanisms of gene regulation for these critical cardiac apoptosis effectors, the determinants of Nix and BNip3 promoter activation were elucidated by luciferase ... 100 nm), or isoproterenol (10 μm). In contrast, Nix transcription was increased by phenylephrine but not by ... but not PKCϵ or dominant negative PKCα, increased Nix transcription. Multiple Nix promoter GC boxes bound transcription ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2005 - Elsevier BV | Journal of Biological Chemistry
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Mitinori Saitou, Kazuki Kurimoto,
... For example, Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... of 148 bpHammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... data from Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... Scholar and Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... protocol by Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... genic regions (Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... previous reports (Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ...
Tópico(s): Renal and related cancers
2014 - Elsevier BV | Developmental Cell
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios Concertes Finale. Musical work.
0000 - Gale Group | NCCO British Theatre
Weili Liu, Xinxing Wang, Jingbo Gong, Zhusong Mei, Xiujie Gao, Yun Zhao, Jing Ma, Lingjia Qian,
... to exert fibrogenic actions in the injured organ. Nix plays a critical role in pressure overload-induced ... apoptosis. However, cardiac remodeling also includes fibrosis. Whether Nix is involved in stress-induced fibrosis remains unclear. ... study was designed to determine the role of Nix in NE-induced NIH/3T3 fibroblasts. The results showed that Nix was upregulated and closely associated with cell proliferation, ... NIH/3T3 fibroblasts following NE treatment. Overexpression of Nix promoted collagen and fibronectin expression, whereas the suppression ...
Tópico(s): Cardiac Structural Anomalies and Repair
2014 - Springer Science+Business Media | Cell Stress and Chaperones
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Roxanne Stiglitz, Elena A. Mikhailova, Christopher J. Post, Mark A. Schlautman, Julia L. Sharp,
... and preference for such innovations among users. The Nix Pro color sensor, an inexpensive mobile color sensor, ... resources) had a hands-on experience with the Nix Pro color sensor and the Munsell color chart ... methods of color determination (Munsell color chart and Nix Pro). Students then filled out a survey providing ... percent of the students preferred to use the Nix Pro color sensor over the Munsell color chart, 76% judged the Nix Pro to be less subjective to environmental conditions, and 91% believed the Nix Pro to be less subjective to user sensitivities. ...
Tópico(s): Genetics, Bioinformatics, and Biomedical Research
2016 - Wiley | Natural sciences education
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Chen Gao, Jeannick Cizeau, Christine Vande Velde, Jae Hoon Park, Gracjan Bozek, Shay‐Lee Bolton, Lianfa Shi, D. Dubik, Arnold H. Greenberg,
We have identified Nix, a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Nip3. Human and murine Nix have a 56 and 53% amino acid identity ... and murine Nip3, respectively. The carboxyl terminus of Nix, including a transmembrane domain, is highly homologous to ... Nip3 maps to chromosome 14q11.2–q12, whereas Nix/BNip3L was found on 8q21. Nix encodes a 23.8-kDa protein but it ... that it homodimerizes similarly to Nip3. Following transfection, Nix protein undergoes progressive proteolysis to an 11-kDa ...
Tópico(s): Hepatitis B Virus Studies
1999 - Elsevier BV | Journal of Biological Chemistry