... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios Duetto Nix. Musical work.
0000 - Gale Group | NCCO British Theatre
Min Chen, Peng Li, Ping Gong, Xiaoli Zheng, Tao Sun, Xiaoqiao Zhang, Jiangtao Huo,
... rats. The targeting relation between miR-30b and NIX was predicted and verified. Then, sh-NIX was transfected into PD rats, and the effects of miR-30b and NIX on MMP, LC3, and P62 were assessed. When miR-30b was overexpressed using agomiR-30b, the NIX and BNIP3 levels were detected. Baicalein increased the ... inhibited miR-30b expression and miR-30b targeted NIX. miR-30b upregulation or NIX silencing reversed the effect of baicalein on MMP and mitochondrial autophagy. Baicalein upregulated NIX and BNIP3 expressions, while miR-30b overexpression inhibited ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2021 - Hindawi Publishing Corporation | Biochemistry Research International
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios Pantomime "Nix". Musical work.
0000 - Gale Group | NCCO British Theatre
Mashun Onishi, Koji Yamano, Miyuki Sato, Noriyuki Matsuda, Koji Okamoto,
... interacting protein 3 BNIP3L Nip3-like protein X (NIX)/BNIP3-like protein CCCP Carbonyl cyanide m-chlorophenylhydrazone ... mitophagy receptors BNIP3, BCL2L13, FKBP8 (C), FUNDC1, and NIX (D) bind to ATG8 family proteins and then ... group includes BNIP3 and BNIP3L (also known as NIX) (Boyd et al, 1994; Matsushima et al, 1998; ... FKBP proteins (Bhujabal et al, 2017). BNIP3 and NIX BNIP3 is required for efficient turnover of mitochondria ... LC3 interactions (Zhu et al, 2013) (Fig 2C). NIX shows homology to BNIP3 (53–56% amino acid ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2021 - Springer Nature | The EMBO Journal
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios "Score" of Pantomime "Nix". Musical ...
0000 - Gale Group | NCCO British Theatre
Juyi Zhang, Guiqiang Yuan, Tianyu Liang, Pengjie Pan, Xiang Li, Haiying Li, Haitao Shen, Zhong Wang, Gang Chen,
Nix is located in the outer membrane of mitochondria, mediates mitochondrial fission and implicated in many neurological diseases. However, the association between Nix and subarachnoid hemorrhage (SAH) has not previously been ... study was designed to evaluate the expression of Nix and its role in early brain injury (EBI) ... blood into the prechiasmatic cistern. The expression of Nix was investigated by Western blot and immunohistochemistry. Next, Nix-specific overexpression plasmids and small interfering RNAs (siRNAs) ...
Tópico(s): Intracerebral and Subarachnoid Hemorrhage Research
2020 - Frontiers Media | Frontiers in Neuroscience
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios Solo's in Ballet of ...
0000 - Gale Group | NCCO British Theatre
Sinsuk Han, Yu Young Jeong, Preethi Sheshadri, Xiao Su, Qian Cai,
... Rheb mediates mitophagy initiation in axons that requires Nix A, B. Representative kymographs (A) and quantitative analysis ( ... images (G) and quantitative analysis (H) showing that Nix RNAi reduces mitochondrial recruitment of Rheb in axons ... white arrows) in axons expressing scrambled shRNA or Nix shRNA was quantified (H). I, J. Impaired biogenesis of mitophagosomes within CCCP-treated axons expressing Nix shRNA. Note that Rheb-associated mitophagosomes are markedly decreased following Nix RNAi. The number of Rheb-targeted autophagic vacuoles ( ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2020 - Springer Nature | EMBO Reports
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios Musical work.
0000 - Gale Group | NCCO British Theatre
J. C. Cook, C. M. Dalle Ore, S. Protopapa, Richard P. Binzel, Richard Cartwright, D. P. Cruikshank, A. M. Earle, W. M. Grundy, Kimberly Ennico, C. J. A. Howett, Donald E. Jennings, Allen Lunsford, C. B. Olkin, A. H. Parker, Philippe Sylvain, Dennis C. Reuter, B. Schmitt, J. A. Stansberry, S. A. Stern, A. Verbiscer, H. A. Weaver, L. A. Young,
... imager, New Horizons obtained the first spectra of Nix, Hydra, and Kerberos and detected the 1.5 ... of H2O-ice on all three satellites. On Nix and Hydra, New Horizons also detected bands at ... a definitive conclusion. We use the observations of Nix and Hydra to estimate the surface temperature and ... K ( < 150 K with 1-σ error) for Nix and Hydra, respectively. We find crystalline H2O-ice fractions of 78−22+12% and > 30% for Nix an Hydra, respectively. New Horizons observed Nix and Hydra twice, about 2–3 hours apart, ...
Tópico(s): Space Satellite Systems and Control
2018 - Elsevier BV | Icarus
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Dan Xu, Panpan Chen, Bao Wang, Yanzhe Wang, Naijun Miao, Fan Yin, Qian Cheng, Zhuanli Zhou, Hongyan Xie, Li Zhou, Jun Liu, Xiaoxia Wang, Roy Zent, Limin Lü, Wei Zhang,
... experiment, the role of NIP3-like protein X (NIX)-mediated mitophagy was investigated in proteinuria-induced renal injury. In this study, we demonstrated that NIX expression was reduced in renal tubules and correlated ... of the proteinuria in patients. In proteinuric mice, NIX-mediated mitophagy was significantly suppressed. Meanwhile, the proteinuric ... mitochondrial fragmentation, and tubular cell apoptosis. Overexpression of NIX attenuated those disruptions in proteinuric mice. In cultured ... tubular epithelial cells, albumin induced a decrease in NIX-mediated mitophagy and an increase in cell apoptosis. ...
Tópico(s): Autophagy in Disease and Therapy
2018 - American Physical Society | AJP Renal Physiology
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Roxanne Stiglitz, Elena A. Mikhailova, Christopher J. Post, Mark A. Schlautman, Julia L. Sharp,
... and preference for such innovations among users. The Nix Pro color sensor, an inexpensive mobile color sensor, ... resources) had a hands-on experience with the Nix Pro color sensor and the Munsell color chart ... methods of color determination (Munsell color chart and Nix Pro). Students then filled out a survey providing ... percent of the students preferred to use the Nix Pro color sensor over the Munsell color chart, 76% judged the Nix Pro to be less subjective to environmental conditions, and 91% believed the Nix Pro to be less subjective to user sensitivities. ...
Tópico(s): Genetics, Bioinformatics, and Biomedical Research
2016 - Wiley | Natural sciences education
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Mitinori Saitou, Kazuki Kurimoto,
... For example, Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... of 148 bpHammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... data from Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... Scholar and Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... protocol by Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... genic regions (Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ... previous reports (Hammoud et al., 2009Hammoud S.S. Nix D.A. Zhang H. Purwar J. Carrell D. ...
Tópico(s): Renal and related cancers
2014 - Elsevier BV | Developmental Cell
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Weili Liu, Xinxing Wang, Jingbo Gong, Zhusong Mei, Xiujie Gao, Yun Zhao, Jing Ma, Lingjia Qian,
... to exert fibrogenic actions in the injured organ. Nix plays a critical role in pressure overload-induced ... apoptosis. However, cardiac remodeling also includes fibrosis. Whether Nix is involved in stress-induced fibrosis remains unclear. ... study was designed to determine the role of Nix in NE-induced NIH/3T3 fibroblasts. The results showed that Nix was upregulated and closely associated with cell proliferation, ... NIH/3T3 fibroblasts following NE treatment. Overexpression of Nix promoted collagen and fibronectin expression, whereas the suppression ...
Tópico(s): Cardiac Structural Anomalies and Repair
2014 - Springer Science+Business Media | Cell Stress and Chaperones
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Yuntao Lu, Leyu Wang, Minyi He, Wenhua Huang, Hong Li, Yongkui Wang, Jiming Kong, Songtao Qi, Jun Ouyang, Xiaozhong Qiu,
Previous reports indicate that the NIX/BNIP3L gene acts as a pro-apoptotic factor by interacting with BCL2 and BCL-XL, playing an important role in hypoxia- ... tumor suppressor. However, many studies also showed that NIX is linked to a protective role and cell ... activation inhibitor) expression, but a greater expression of Nix and p-NF-κB proteins in the Nix-wt U251 cells, which was not observed in the Nix-kn cells under hypoxic conditions. Using electrophoretic mobility ... of NF-κB was detected only in the Nix-wt U251 cells with hypoxia. These data imply ...
Tópico(s): Cancer-related molecular mechanisms research
2012 - Public Library of Science | PLoS ONE
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Yun Chen, William Lewis, Abhinav Diwan, Emily H. Cheng, Scot J. Matkovich, Gerald W. Dorn,
... observed regulation of intracellular calcium stores by reticular Nix. Here, we report effects of Nix targeting to mitochondria or ER on cell death pathways and heart failure progression. Nix-deficient fibroblasts expressing mitochondrial-directed or ER-directed Nix mutants exhibited similar cytochrome c release, caspase activation, ... V and TUNEL labeling, and cell death. ER-Nix cells, but not mitochondrial-Nix cells, showed dissipation of mitochondrial inner membrane potential, ... implicating the mitochondrial permeability transition pore (MPTP). ER-Nix cells were not protected from death by caspase ...
Tópico(s): ATP Synthase and ATPases Research
2010 - National Academy of Sciences | Proceedings of the National Academy of Sciences
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Héctor Sandoval, Perumal Thiagarajan, Swapan K. Dasgupta, Armin Schumacher, Josef T. Prchal, Min Chen, Jin Wang,
... that a member of the Bcl-2 family, Nix/Bnip3L, helps eliminate organelles by by autophagy (or 'eating') of the mitochondria. Nix−/− mice developed anaemia with reduced mature erythrocytes and ... erythroid precursors. Erythrocytes in the peripheral blood of Nix−/− mice exhibited mitochondrial retention and reduced lifespan in ... that a member of the Bcl-2 family, Nix, helps eliminate organelles by autophagy of the mitochondria. Erythrocytes in the peripheral blood of Nix−/− mice exhibited mitochondrial retention and reduced lifespan in ...
Tópico(s): Hemoglobinopathies and Related Disorders
2008 - Nature Portfolio | Nature
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios Concertes Finale. Musical work.
0000 - Gale Group | NCCO British Theatre
Abhinav Diwan, Scot J. Matkovich, Qunying Yuan, Wen Zhao, Atsuko Yatani, Joan Heller Brown, Jeffery D. Molkentin, Evangelia G. Kranias, Gerald W. Dorn,
Transcriptional upregulation of the proapoptotic BCL2 family protein NIX limits red blood cell formation and can cause ... poorly defined. Here, we show complementary mechanisms for NIX-mediated cell death involving direct and ER/sarcoplasmic ... mediated (ER/SR-mediated) mitochondria disruption. Endogenous cardiac NIX and recombinant NIX localize both to the mitochondria and to the ... stores are proportional to the level of expressed NIX. Whereas Nix ablation was protective in a mouse model of ... correction of the decreased SR calcium content of Nix-null mice restored sensitivity to cell death and ...
Tópico(s): Autophagy in Disease and Therapy
2008 - American Society for Clinical Investigation | Journal of Clinical Investigation
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Michael Wilhelm, Zhiheng Xu, Nickolay V. Kukekov, Stephen Gire, Lloyd A. Greene,
Nix, a pro-apoptotic BH3-only protein, promotes apoptosis of non-neuronal cells, although the mechanisms involved ... bait, we identified an interaction between POSH and Nix. Co-immunoprecipitation and in vitro binding studies confirmed a direct interaction between POSH and Nix in mammalian cells. When overexpressed in HEK293 cells, Nix promotes apoptosis along with enhanced phosphorylation/activation of ... effects appear to be dependent on POSH because Nix does not promote either JNK/c-Jun phosphorylation ...
Tópico(s): Nuclear Receptors and Signaling
2006 - Elsevier BV | Journal of Biological Chemistry
... Oscar Barrett. 'Overture and full score to Pantomime 'Nix''. Complete orchestral score for 'Nix'. Dated 23rd December 1872/73 and marked with ... monogram. 40Mm. thick. 'Solos in Ballet of Pantomime 'Nix'' Full score. folios
0000 - Gale Group | NCCO British Theatre
Anita Gálvez, Eric W. Brunskill, Yehia Marreez, Bonnie J. Benner, Kelly M. Regula, Lorrie A. Kirschenbaum, Gerald W. Dorn,
Up-regulation of myocardial Nix and BNip3 is associated with apoptosis in cardiac hypertrophy and ischemia, respectively. To identify mechanisms of gene regulation for these critical cardiac apoptosis effectors, the determinants of Nix and BNip3 promoter activation were elucidated by luciferase ... 100 nM), or isoproterenol (10 microM). In contrast, Nix transcription was increased by phenylephrine but not by ... PKC epsilon or dominant negative PKC alpha, increased Nix transcription. Multiple Nix promoter GC boxes bound transcription ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2005 - Elsevier BV | Journal of Biological Chemistry