Paulo Fonseca, João Almeida, Nuno Bettencourt, Nuno Ferreira, Mónica Carvalho, Wilson Ferreira, Daniel Caeiro, Helena Gonçalves, José Ribeiro, Alberto Rodrigues, Pedro Braga, Vasco Gama,
Vascular access site complications in transfemoral (TF) transcatheter aortic valve implantation (TAVI) are associated with increased morbidity and mortality; however, their incidence and predictors are conflicting between studies. This study sought to assess the incidence and predictors of vascular access site complications in patients undergoing TF TAVI.A total of 140 patients undergoing TF TAVI were included in the study. Minimum iliofemoral diameter and iliofemoral calcium score (CS) were estimated ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2016 - Elsevier BV | Revista Portuguesa de Cardiologia
Nuno Bettencourt, Nuno Ferreira, Amedeo Chiribiri, Andreas Schuster, Francisco Sampaio, Lino Santos, Bruno Melica, Alberto Rodrigues, Pedro Braga, Madalena Teixeira, Adelino Leite‐Moreira, José Silva‐Cardoso, Pedro Portugal, Vasco Gama, Eike Nagel,
Cardiovascular magnetic resonance (CMR) myocardial perfusion imaging (MPI) is a state-of-the-art noninvasive modality for detection of myocardial ischemia and coronary artery disease. Magnetic resonance coronary angiography (MRCA) allows visualization of the coronary tree, but its incremental value as part of a CMR protocol including MPI and late gadolinium enhancement (LGE) is not well established. We aimed to evaluate the additive diagnostic value of a 3-dimensional whole-heart MRCA integration into ...
Tópico(s): Coronary Interventions and Diagnostics
2013 - Lippincott Williams & Wilkins | Circulation Cardiovascular Imaging
Nuno Bettencourt, Nuno Ferreira, Daniel Leite, Mónica Carvalho, Wilson Ferreira, Andreas Schuster, Amedeo Chiribiri, Adelino Leite‐Moreira, José Silva‐Cardoso, Eike Nagel, Vasco Gama,
This study sought to compare computed tomography delayed enhancement (CTDE) against cardiac magnetic resonance (CMR) late gadolinium enhancement (LGE) for detection of ischemic scar and to test the additive value of CTDE as part of a comprehensive multidetector computed tomography (MDCT) stress–rest protocol including computed tomography perfusion (CTP) and computed tomography angiography (CTA) for the diagnosis of significant coronary artery disease (CAD). CTDE has been recently described as a promising ...
Tópico(s): Radiation Dose and Imaging
2013 - Elsevier BV | JACC. Cardiovascular imaging
Pedro A. Sousa, Nuno Bettencourt, Nuno Ferreira, Mónica Carvalho, Daniel Leite, Wilson Ferreira, Ilídio de Jesus, Vasco Gama,
Differentiation of ischemic from non-ischemic etiology in heart failure (HF) patients has both therapeutic and prognostic implications. One possible approach to this differentiation is direct visualization of the coronary tree. Multidetector computed tomography (MDCT) has emerged as an alternative to invasive coronary angiography (ICA), but its performance and additional clinical value are still not well validated in patients with left ventricular (LV) dysfunction. We aimed to assess the value of coronary ...
Tópico(s): Radiation Dose and Imaging
2014 - Elsevier BV | Revista Portuguesa de Cardiologia
Eulália Pereira, Nuno Bettencourt, Nuno Ferreira, Andreas Schuster, Amedeo Chiribiri, João Primo, Madalena Teixeira, Lino Simões, Adelino Leite‐Moreira, José Silva‐Cardoso, Vasco Gama, Eike Nagel,
Cardiac magnetic resonance myocardial perfusion imaging (CMR-MPI) is considered a state-of-the-art non-invasive modality for ischemia detection but its additive value in a multiple-test strategy in patients with suspected coronary artery disease (CAD) is not fully validated. We aimed to evaluate CMR-MPI integration with exercise treadmill test (ETT) for the diagnostic workup of patients with suspected CAD, having invasive fractional flow reserve (FFR) as reference standard.In this prospective single- ...
Tópico(s): Coronary Interventions and Diagnostics
2013 - Elsevier BV | International Journal of Cardiology
Ricardo Ladeiras‐Lopes, Nuno Bettencourt, Nuno Ferreira, Francisco Sampaio, Gustavo Pires‐Morais, Lino Santos, Bruno Melica, Alberto Rodrigues, Pedro Braga, Adelino Leite‐Moreira, José Silva‐Cardoso, Vasco Gama,
High amounts of coronary artery calcium limit image quality and diagnostic accuracy of multidetector computed tomography (MDCT) angiography (CTA) regarding the assessment of obstructive coronary artery disease (CAD). CT myocardial perfusion imaging may represent an opportunity to overcome this limitation.To explore the additive value of CT myocardial perfusion to CTA depending on the patient's calcium score and in comparison to the reference standard of invasive coronary angiography plus fractional ...
Tópico(s): Advanced X-ray and CT Imaging
2016 - Elsevier BV | Journal of cardiovascular computed tomography
Dipak Kotecha, Jeroen J. Bax, Céline Carrera, Barbara Casadei, Béla Merkely, Stefan D. Anker, Panos Vardas, Peter Kearney, Marco Roffi, Michelle Ros, Alec Vahanian, Franz Weidinger, Rоnen Beeri, Andrzej Budaj, Paolo Calabrò, Katarzyna Czerwińska, Flavio D’Ascenzi, Tom De Potter, Kevin Fox, Juha Hartikainen, Brendan McAdam, Davor Miličić, Agnés Pasquet, Alessandro Sionís, S.M. Afzal Sohaib, Costas Tsioufis, Patrick M.J. Verhorst, Paulus Kirchhof, Armağan Altun, Manuel Anguita, Rusudan Agladze, Stephan Baldus, Nuno Bettencourt, Alexander Borg, Haran Burri, David Carballo, Milica Dekleva, Aurel Demiraj, Jaan Eha, Andrejs Ērglis, Norbert Frey, Anna Freyschuss, Carmen Ginghină, Lino Gonçalves, Julia Grapsa, José Ramón González‐Juanatey, Róbert Hatala, Þórdís Jóna Hrafnkelsdóttir, Richard Isnard, Line Joubert, Aušra Kavoliūnienė, Alina Kerimkulova, Elena Kinova, Jesper Kjærgaard, Eleni Kletsiou, А. V. Kontsevaya, Ulf Landmesser, Dorin Lîsîi, Julia Mascherbauer, Mohamed Sami Mourali, Joseph Moutiris, Barbara J.M. Mulder, Gamela Nasr, E. G. Nesukay, Latifa Oukerraj, Lidija Poposka, Susanna Price, Regina Ribeiras, Svein Rotevatn, Rafael Sádaba, Per Anton Sirnes, Russell E.A. Smith, Dragan Lović, Felix C. Tanner, Ivo A.C. van der Bilt, Olivier Varenne, Stephan von Haehling, Marco Zavatta, Aurel Demiraj, Rоnen Beeri, Julia Mascherbauer, Paolo Calabrò, Franz Weidinger, Flavio D’Ascenzi, Agnés Pasquet, Alina Kerimkulova, Tom De Potter, Andrejs Ērglis, Dragan Lović, Iveta Bajāre, Russell Smith, Aušra Kavoliūnienė, Afzal Sohaib, Lidija Poposka, Elena Kinova, Alexander Borg, Davor Miličić, Dorin Lîsîi, Joseph Moutiris, Latifa Oukerraj, Jesper Kjærgaard, Patrick M.J. Verhorst, Gamela Nasr, Svein Rotevatn, Gamal M. Shaban, Andrzej Budaj, Jaan Eha, Katarzyna Czerwińska, Juha Hartikainen, Nuno Bettencourt, Richard Isnard, Carmen Ginghină, Rusudan Agladze, Yulia Balanova, Norbert Frey, Marco Zavatta, Stefan D. Anker, Milica Dekleva, Anastasia Kitsiou, Róbert Hatala, Costas Tsioufis, Manuel Anguita, Christina Chrysoou, Anna Freyschuss, Zoltán Csanádi, David Carballo, Þórdís Jóna Hrafnkelsdóttir, Þórarinn Guðnason, Brendan McAdam, Barbra Dalton, Mohamed Sami Mourali, Armağan Altun, E. G. Nesukay,
The provision of high-quality education allows the European Society of Cardiology (ESC) to achieve its mission of better cardiovascular practice and provides an essential component of translating new evidence to improve outcomes.The 4th ESC Education Conference, held in Sophia Antipolis (December 2016), brought together ESC education leaders, National Directors of Training of 43 ESC countries, and representatives of the ESC Young Community. Integrating national descriptions of education and cardiology ...
Tópico(s): Innovations in Medical Education
2018 - Oxford University Press | European Heart Journal
Natércia Guerra Simões, Ana Bettencourt, Nuno Monge, Isabel Ribeiro,
Multiple strategies have been recommended for prevention and control of antibacterial resistance. Solutions will need to be found soon if we are not to run the serious risk of losing the ability to treat bacterial infections, especially the ones arising from multi-resistant strains. Deep knowledge of the resistance mechanisms followed by novel therapeutic drugs and vaccines are needed. A consolidated, multidisciplinary and regulated strategy is required by this challenge.This review will be focused ...
Tópico(s): Biochemical and Structural Characterization
2016 - Bentham Science Publishers | Mini-Reviews in Medicinal Chemistry
Paulo Fonseca, B. Henriques de Figueiredo, Carla Almeida, João Almeida, Nuno Bettencourt, Francisco Sampaio, Nuno Ferreira, Helena Gonçalves, Pedro Braga, Vasco Gama Ribeiro,
Objective This study sought to evaluate the impact of aortic valve (AV) and left ventricle outflow tract (LVOT) calcium on paravalvular regurgitation (PVR) and need for balloon post‐dilatation (BPD) during transcatheter aortic valve implantation (TAVI). Methods The overall study population comprised 152 patients. Calcium mass and volume of AV and LVOT were estimated from contrast‐enhanced multislice computed tomography imaging, using 3 thresholds for calcium detection [650, 850, and 1,050 Hounsfield units ( ...
Tópico(s): Cardiac Imaging and Diagnostics
2016 - Wiley | Journal of Interventional Cardiology
Marta Viana, Olga Laszczyńska, Sandra Mendes, Fernando Friões, Patrícia Lourenço, Paulo Bettencourt, Nuno Lunet, Ana Azevedo,
Adherence to medication is crucial to improve clinical outcomes in patients with heart failure (HF). However, at least 1 out of 4 patients is nonadherent to his or her medication. Several studies have quantified medication adherence in HF patients, monitoring only 1 drug with the Medication Event Monitoring System (MEMS). Some authors have argued that monitoring 1 drug reflects the whole adherence behavior, although there is some evidence of important differences in adherence to distinct drug classes. ...
Tópico(s): Heart Failure Treatment and Management
2014 - Academy of Managed Care Pharmacy | Journal of Managed Care Pharmacy
Nuno Bettencourt, João Rocha, Nuno Ferreira, Gustavo Pires‐Morais, Mónica Carvalho, Daniel Leite, Bruno Melica, Lino Santos, Alberto Rodrigues, Pedro Braga, Madalena Teixeira, Lino Simões, Adelino Leite‐Moreira, Silva Cardoso, Eike Nagel, Vasco Gama,
Background Preliminary studies have shown the potential of myocardial computed tomography perfusion (CTP) analysis for ischemia detection in both animals and humans. Objective To provide validation data on stress-rest CTP protocols as additive tools to improve the accuracy of multidetector computed tomography (MDCT) for coronary artery disease (CAD) in symptomatic patients. Methods Ninety symptomatic patients with suspected CAD (62 ± 8 years, 66% males) underwent both MDCT and invasive coronary angiography ( ...
Tópico(s): Advanced X-ray and CT Imaging
2011 - Elsevier BV | Journal of cardiovascular computed tomography
Luís M. A. Bettencourt, Nuno D. Antunes, Wojciech H. Zurek,
The Ginzburg temperature has historically been proposed as the energy scale of formation of topological defects at a second order symmetry breaking phase transition. More recently alternative proposals which compute the time of formation of defects from the critical dynamics of the system, have been gaining both theoretical and experimental support. We investigate, using a canonical model for string formation, how these two pictures compare. In particular we show that prolonged exposure of a critical ...
Tópico(s): Theoretical and Computational Physics
2000 - American Physical Society | Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D. Particles and fields
Francisco Sampaio, Pablo Lamata, Nuno Bettencourt, Sophie Charlotte Alt, Nuno Ferreira, Johannes T. Kowallick, Joana Pimenta, Shelby Kutty, José Carlos Soares de Fraga, Michael Steinmetz, Paulo Bettencourt, Vasco Gama, Andreas Schuster,
Liver cirrhosis has been shown to affect cardiac performance. However cardiac dysfunction may only be revealed under stress conditions. The value of non-invasive stress tests in diagnosing cirrhotic cardiomyopathy is unclear. We sought to investigate the response to pharmacological stimulation with dobutamine in patients with cirrhosis using cardiovascular magnetic resonance.
Tópico(s): Liver Disease and Transplantation
2015 - BioMed Central | Journal of Cardiovascular Magnetic Resonance
Ricardo Ladeiras‐Lopes, Francisco Sampaio, Nuno Bettencourt, Ricardo Fontes‐Carvalho, Nuno Ferreira, Adelino Leite‐Moreira, Vasco Gama,
Tópico(s): Adipose Tissue and Metabolism
2017 - Elsevier BV | Revista Española de Cardiología
Ricardo Ladeiras‐Lopes, Francisco Sampaio, Nuno Bettencourt, Ricardo Fontes‐Carvalho, Nuno Ferreira, Adelino Leite‐Moreira, Vasco Gama,
Tópico(s): Cardiovascular Function and Risk Factors
2016 - Elsevier BV | Revista Española de Cardiología (English Edition)
Nuno Bettencourt, Amedeo Chiribiri, Andreas Schuster, Nuno Ferreira, Francisco Sampaio, Gustavo Pires‐Morais, Lino Santos, Bruno Melica, Alberto Rodrigues, Pedro Braga, Luís Filipe Azevedo, Madalena Teixeira, Adelino Leite‐Moreira, José Silva‐Cardoso, Eike Nagel, Vasco Gama,
This study sought to compare the diagnostic performance of a multidetector computed tomography (MDCT) integrated protocol (IP) including coronary angiography (CTA) and stress-rest perfusion (CTP) with cardiac magnetic resonance myocardial perfusion imaging (CMR-Perf) for detection of functionally significant coronary artery disease (CAD). MDCT stress-rest perfusion methods were recently described as adjunctive tools to improve CTA accuracy for detection of functionally significant CAD. However, only a ...
Tópico(s): Advanced X-ray and CT Imaging
2013 - Elsevier BV | Journal of the American College of Cardiology
Nuno Bettencourt, Amedeo Chiribiri, Andreas Schuster, Nuno Ferreira, Francisco Sampaio, Ricardo Duarte, Lino Santos, Bruno Melica, Alberto Rodrigues, Pedro Braga, Madalena Teixeira, Lino Simões, Adelino Leite‐Moreira, José Silva‐Cardoso, Eike Nagel, Pedro Portugal, Vasco Gama,
Tópico(s): Coronary Interventions and Diagnostics
2012 - Elsevier BV | International Journal of Cardiology
Andrew J. Einstein, Cole B. Hirschfeld, Michelle C. Williams, João V. Vítola, Nathan Better, Todd C. Villines, Rodrigo Cerci, Leslee J. Shaw, Andrew D. Choi, Sharmila Dorbala, Ganesan Karthikeyan, Bin Lü, В. Е. Синицын, Alexey Ansheles, Takashi Kudo, Chiara Bucciarelli‐Ducci, Bjarne Linde Nørgaard, Pál Maurovich‐Horvat, Roxana Campisi, Elisa Milan, Lizette Louw, Adel H. Allam, Mona Bhatia, Lorenzo R. Sewanan, Eli Malkovskiy, Yosef Cohen, Michael Randazzo, Jagat Narula, Olga Morozova, Thomas N.B. Pascual, Yaroslav Pynda, Maurizio Dondi, Diana Páez, Andrew J. Einstein, Diana Páez, Maurizio Dondi, Nathan Better, Rodrigo Cerci, Sharmila Dorbala, Ganesan Karthikeyan, Thomas N.B. Pascual, Leslee J. Shaw, Todd C. Villines, João V. Vítola, Michelle C. Williams, Yaroslav Pynda, Gerd Hinterleitner, Yao Lu, Olga Morozova, Zhuoran Xu, Cole B. Hirschfeld, Yosef Cohen, Ikenna Erinne, Eli Malkovskiy, Michael Randazzo, Lorenzo R. Sewanan, Mrinali Shetty, Andrew D. Choi, Juan Lopez‐Mattei, Purvi Parwani, A Goda, E Shirka, S.E. Bouyoucef, Lydia Chelghoum, Farouk Mansouri, Abdelkader Medjahedi, Qaïs Naïli, M. Ridouh, Diego Alasia, Lucia Alberghina, Natalia Aramayo, Diego Buchara, Franco Gabriel Busso, Jose Javier Bustos Rivadero, Jorge Camilletti, Hugo Campanelli, Roxana Campisi, Ricardo Belisario Castro, Mariana Daicz, Horacio del Riego, Laura Dragonetti, Diego Echazarreta, Juan Erriest, Fernando Faccio, Adolfo Facello, Hugo Gallegos, Ricardo Geronazzo, H. Glait, Victor Hasbani, Victor C.L. de Jager, Julio Manuel Lewkowicz, Jose Maria Lotti, Neiva Maciel, Osvaldo Masoli, Edgardo Mastrovito, Maria Medus, Maria Fernanda Merani, Susana Molteni, Marcos Montecinos, Gustavo Parisi, Claudio Pereyra Sueldo, Diego Pérez de Arenaza, Luís F. Quintana, Alejandro Radzinschi, Marcela Redruello, Marina Rodríguez, Horacio Rojas, Arturo Romero Acuña, Daniel Schere, Sonia Traverso, Gustavo Vázquez, Susana Zeffiro, Mari Sakanyan, Scott Beuzeville, Raef Boktor, Michael J. Crowley, D'Arne Downie, Girish Dwivedi, Barry Elison, Omar Farouque, Kim Jasper, S. Joshi, Joseph Lee, Kenneth Lee, Elaine Lui, Peter Mcconachie, Joanne Meaker, Dee Nandurkar, Johanne Neill, Edward J. OʼRourke, P. O'Sullivan, George Pandos, Manuja Premaratne, David L. Prior, Natalie Rutherford, Connor Saunders, Kim Taubman, A. Tauro, Andrew J. Taylor, J. Theuerle, Paul V. Thomas, Jonathan Tow, Anthony Upton, Shankar Vamadevan, Victor S. Wayne, Eva A. Wegner, David Wong, J. Younger, Dietrich Beitzke, Gudrun Feuchtner, Oliver Sommer, Konrad Weiß, N. Maroz-Vadalazhskaya, Uladzimir Tserakhau, Filip Homans, Caroline M. Van De Heyning, Raúl Araujo, Valentina Soldat-Stanković, Siniša Stanković, Augusto Almeida, Carlos Anselmi, Guilherme S.A. Azevedo, Márcio Sommer Bittencourt, Diego Bromfman Pianta, Estêvan Vieira Cabeda, Lara Cristiane Terra Ferreira Carreira, Rodrigo Cerci, Igor Machado Coelho, Fernando Fernandes, Andrea De Lorenzo, Roberta Delgado, Fernanda Erthal, Fábio Fernandes, Juliano Lara Fernandes, Thiago Ferreira de Souza, Murilo Foppa, Wilson Furlan Matos Alves, Cibele Gontijo, Ilan Gottlieb, Gabriel Blacher Grossman, Maria Helena Albernaz Siqueira, César Higa Nomura, Kátia Hiromoto Koga, Ronaldo de Souza Leão Lima, Rafael Willain Lopes, Hugo Humberto Marçal Filho, Paulo César Masiero, Luiz Eduardo Mastrocola, Maria Eduarda Menezes de Siqueira, Cláudio Tinoco Mesquita, Danilo Naves, Filipe Penna, Ibraim Pinto, Thércio Rocha, Juliana Leal Rocha, Alfredo José Rodrigues, Leila Salioni, Adelina Sanches, Marcelo Henrique dos Santos, Leonardo Sara Da Silva, Paulo R. Schvartzman, Cristina Sebastião Matushita, Tiago Senra, Marcelo Silva, Carlos Eduardo Lopes Soares, Bernardo Spiro, Carlos Eduardo Suaide Silva, Rafael Torres, Guilherme Urpia Monte, Andréa Andrade Vilela, Alexandre Volney Villa, João V. Vítola, Themissa Voss, Roberto Waltrick, Marcello Zapparoli, Hamid Naseer, Marina Garcheva-Tsacheva, Tiémégna Florence Ouattara, Sarameth Thou, Soley Varoeun, Gad Abikhzer, Rob Beanlands, Michael Chetrit, Dominique DaBreo, Carole Dennie, Matthias G. Friedrich, Mohmmed Nassoh Hafez, Kate Hanneman, Robert J.H. Miller, Anastasia Oikonomou, Idan Roifman, Gary R. Small, Vikas Tandon, Adwait Trivedi, James R. White, Katherine Zukotynski, Rita Alay, Carmen Concha, Teresa Massardo, Pedro Abad, Luz Kelly Anzola, Harold Arturo, Luis Benitez, Alberto Cadena, Carlos Caicedo Zamudio, Antonio Calderón, Claudia T. Gutierrez Villamil, Claudia Jaimes, Juan L. Londono, Nelson Loyola López, Sonia Merlano-Gaitan, Ramon Murgieitio-Cabrera, Manuel Valencia, Damiana Vergel, Alejandro Zuluaga Santamaria, Felix Solis, Tonči Batinić, Maja Franceschi, Maja Hrabak Paar, Marina Prpic, Cuba Juan Felipe Batista, Lázaro O. Cabrera, Amalia Peix, Yamilé Peña, Luis Manuel Rochela Vázquez, Ioannis Ntalas, Milan Kamínek, Vladimír Kincl, Otto Lang, Jawdat Abdulla, Morten Bøttcher, Martin Busk, Uka Geisler, Lars Christian Gormsen, Nicolaj C. Hansson, Søren Hess, Jens D. Hove, Lars Thorbjoern Jensen, Magnus T. Jensen, Kristian Kragholm, Bjarne Linde Nørgaard, Kristian Altern Øvrehus, Jan Rasmussen, Niels Peter Rønnow Sand, Hanne Maare Søndergaard, Tomás Zaremba, Herwin Speckter, Nelson Amores, Mayra Sanchez Velez, Taghreed Abd Alrahman, Sherif Abd Elsamad, Alia Abdelfattah, Adel H. Allam, Sameh Elkaffas, Mona Hassan, Elshaymaa Mohamed Hussein,
The extent to which health care systems have adapted to the COVID-19 pandemic to provide necessary cardiac diagnostic services is unknown. The aim of this study was to determine the impact of the pandemic on cardiac testing practices, volumes and types of diagnostic services, and perceived psychological stress to health care providers worldwide. The International Atomic Energy Agency conducted a worldwide survey assessing alterations from baseline in cardiovascular diagnostic care at the pandemic' ...
Elsevier BV
Cole B. Hirschfeld, Leslee J. Shaw, Michelle C. Williams, Ryan Lahey, Todd C. Villines, Sharmila Dorbala, Andrew D. Choi, Nishant R. Shah, David A. Bluemke, Daniel S. Berman, Ron Blankstein, Maros Ferencik, Jagat Narula, David E. Winchester, Eli Malkovskiy, Benjamin Goebel, Michael Randazzo, Juan Lopez‐Mattei, Purvi Parwani, João V. Vítola, Rodrigo Cerci, Nathan Better, Paolo Raggi, Bin Lü, В. Б. Сергиенко, В. Е. Синицын, Takashi Kudo, Bjarne Linde Nørgaard, Pál Maurovich‐Horvat, Yosef Cohen, Thomas N.B. Pascual, Yaroslav Pynda, Maurizio Dondi, Diana Páez, Andrew J. Einstein, Andrew J. Einstein, Diana Páez, Maurizio Dondi, Nathan Better, Rodrigo Cerci, Sharmila Dorbala, Thomas N.B. Pascual, Paolo Raggi, Leslee J. Shaw, Todd C. Villines, João V. Vítola, Michelle C. Williams, Yaroslav Pynda, Gerd Hinterleitner, Yao Lu, Olga Morozova, Zhuoran Xu, Cole B. Hirschfeld, Yosef Cohen, Benjamin Goebel, Eli Malkovskiy, Michael Randazzo, Andrew D. Choi, Juan Lopez‐Mattei, Purvi Parwani, Mohammad Nawaz Nasery, A Goda, E Shirka, Rabie Benlabgaa, S.E. Bouyoucef, Abdelkader Medjahedi, Qais Nailli, Mariela Agolti, Roberto Agüero, Maria del Carmen Alak, Lucia Graciela Alberguina, Guillermo Arroñada, Andrea Astesiano, Alfredo Astesiano, Carolina Bas Norton, Pablo Benteo, Juan Blanco, Juan Manuel Bonelli, Jose Javier Bustos, Raul Cabrejas, Jorge Cachero, Roxana Campisi, Alejandro Canderoli, Silvia Carames, Patrícia Carrascosa, Ricardo Castro, Oscar Cendoya, Luciano Martin Cognigni, Carlos Collaud, Carlos Collaud, Claudia P. Cortés, Javier Courtis, Daniel Cragnolino, Mariana Daicz, Alejandro De La Vega, Silvia Teresa De Maria, Horacio del Riego, Fernando Dettori, Alejandro Deviggiano, Laura Dragonetti, Mario Embón, Ruben Emilio Enriquez, Jorge Ensinas, Fernando Faccio, Adolfo Facello, Diego Garofalo, Ricardo Geronazzo, Natalia Gonza, Lucas Gutiérrez, Miguel Angel Guzzo, Miguel Angel Guzzo, Victor Hasbani, Melina Huerín, Victor C.L. de Jager, Julio Manuel Lewkowicz, Maria Nieves A. López De Munaín, Jose Maria Lotti, Alejandra Marquez, Osvaldo Masoli, Osvaldo Masoli, Edgardo Mastrovito, Matias Mayoraz, Graciela Eva Melado, Aníbal Mele, Maria Fernanda Merani, Alejandro Meretta, Susana Molteni, Marcos Montecinos, Eduardo Noguera, Carlos Novoa, Claudio Pereyra Sueldo, Sebastian Perez Ascani, Pablo Pollono, Maria Paula Pujol, Alejandro Radzinschi, Gustavo Antônio Raimondi, Marcela Redruello, Marina Rodríguez, Matías Rodríguez, Romina Lorena Romero, Arturo Romero Acuña, Federico Rovaletti, Lucas San Miguel, Lucrecia Solari, Bruno Strada, Sonia Traverso, Sonia Simona Traverzo, Maria del Huerto Velazquez Espeche, Juan Sebastian Weihmuller, Juan Wolcan, Susana Zeffiro, Mari Sakanyan, Scott Beuzeville, Raef Boktor, Patrick Butler, Jennifer Calcott, L. Carr, Virgil Chan, C. Chao, Woon H. Chong, Mark Dobson, D'Arne Downie, Girish Dwivedi, Barry Elison, Jean Engela, Roslyn J. Francis, Anand Gaikwad, Ashok Gangasandra Basavaraj, Bruce Goodwin, Robert Greenough, Christian Hamilton‐Craig, Victar Hsieh, S. Joshi, K. Lederer, Kenneth Lee, Joseph Lee, John Magnussen, Nghi Mai, Gordon Mander, Fiona Murton, Dee Nandurkar, Johanne Neill, Edward J. OʼRourke, P. O'Sullivan, George Pandos, Kunthi Pathmaraj, Alexander Pitman, Rohan Poulter, Manuja Premaratne, David L. Prior, Lloyd J Ridley, Natalie Rutherford, Hamid Salehi, Connor Saunders, Luke Scarlett, Sujith Seneviratne, Deepa Shetty, Ganesh Shrestha, J. Shulman, Vijay Solanki, Tony Stanton, M Stuart, Michael E. Stubbs, I. P. Swainson, Kim Taubman, Andrew J. Taylor, Paul V. Thomas, Steven Unger, Anthony Upton, Shankar Vamadevan, W. van Gaal, Johan Verjans, Demetrius Voutnis, Victor S. Wayne, Peter G. Wilson, David Wong, Kirby Wong, J. Younger, Gudrun Feuchtner, Siroos Mirzaei, Konrad Weiß, N. Maroz-Vadalazhskaya, Olivier Gheysens, Filip Homans, Rodrigo Moreno‐Reyes, Agnés Pasquet, Véronique Roelants, Caroline M. Van De Heyning, Raúl Araujo Ríos, Valentina Soldat-Stanković, Siniša Stanković, Maria Helena Albernaz Siqueira, Augusto Almeida, Paulo Henrique Alves Togni, Jose Henrique Andrade, Luciana Nalone Andrade, Carlos Anselmi, Roberta Araújo, Guilherme Coelho de Azevedo, Sabbrina Bezerra, Rodrigo Biancardi, Gabriel Blacher Grossman, Simone Cristina Soares Brandão, Diego Bromfman Pianta, Lara Cristiane Terra Ferreira Carreira, Bruno Castro, Tien Chang, Fernando Cunali, Roberto C. Cury, Roberto Nery Dantas, Fernando Fernandes, Andrea De Lorenzo, Robson De Macedo Filho, Fernanda Erthal, Fábio Fernandes, Juliano Lara Fernandes, Fábio Fernandes, Thiago Ferreira de Souza, Wilson Furlan Matos Alves, Bruno Galafassi Ghini, Luiz M. G. Gonçalves, Ilan Gottlieb, Marcelo Hadlich, Vinícius Kameoka, Ronaldo de Souza Leão Lima, Adna Lima, Rafael Willain Lopes, Ricardo Machado e Silva, Tiago Magalhães, Fábio Martins Silva, Luiz Eduardo Mastrocola, Fabio Hecht Castro Medeiros, José Cláudio Meneghetti, Vania Naue, Danilo Naves, Roberto Nolasco, César Higa Nomura, Joao Bruno Oliveira, E. Paixão, Filipe Penna de Carvalho, Ibraim Pinto, Priscila Possetti, Mayra Quinta, Rodrigo Rizzo Nogueira Ramos, Ricardo Rocha, Alfredo José Rodrigues, Carlos Rodrigues, Leila Romantini, Adelina Sanches, Sara Santana, Leonardo Sara da Silva, Paulo R. Schvartzman, Cristina Sebastião Matushita, Tiago Senra, Afonso Akio Shiozaki, Maria Eduarda Menezes de Siqueira,
This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-U.S. institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Data were submitted ...
Elsevier BV
Francisco Vasques‐Nóvoa, Tiago L. Laundos, António J. Madureira, Nuno Bettencourt, José Pedro L. Nunes, Fátima Carneiro, José Artur Paiva, Perpétua Pinto‐do‐Ó, Diana S. Nascimento, Adelino Leite‐Moreira, Roberto Roncon‐Albuquerque,
ABSTRACT Septic cardiomyopathy is an increasingly relevant topic in clinical management of septic shock. However, pathophysiological mechanisms and long-term consequences of sepsis-induced myocardial injury are still poorly understood. Herein, new clinical and histological evidence is provided suggesting an association of myocardial edema formation with tissue injury and subsequent remodeling in septic shock patients. This preliminary data supports myocardial edema as a potentially relevant and ...
Tópico(s): Mechanical Circulatory Support Devices
2019 - Lippincott Williams & Wilkins | Shock
Produção Nacional
Revisado por pares
Robert Haase, Peter Schlattmann, Pascal Guéret, Daniele Andreini, Gianluca Pontone, Hatem Alkadhi, Jörg Hausleiter, Mario J. García, Sebastian Leschka, Willem B. Meijboom, Elke Zimmermann, Bernhard Gerber, U. Joseph Schoepf, Abbas Arjmand Shabestari, Bjarne Linde Nørgaard, Matthijs F.L. Meijs, Akira Sato, Kristian Altern Øvrehus, Axel Diederichsen, Shona M. M. Jenkins, Juhani Knuuti, Ashraf Hamdan, Bjørn Halvorsen, Vladimir Mendoza-Rodríguez, Carlos Eduardo Rochitte, Johannes Rixe, Yung Liang Wan, Christoph Langer, Nuno Bettencourt, Eugenio Martuscelli, Saïd Ghostine, Ronny R. Buechel, Konstantin Nikolaou, Hans Mickley, Lin Yang, Zhaqoi Zhang, Marcus Y. Chen, David A. Halon, Matthias Rief, Kai Sun, Beatrice Hirt-Moch, Hiroyuki Niinuma, Roy P. Marcus, Simone Muraglia, Réda Jakamy, Benjamin J.W. Chow, Philipp A. Kaufmann, Jean‐Claude Tardif, César Higa Nomura, Klaus F. Kofoed, Jean-Pierre Laissy, Armin Arbab‐Zadeh, Kakuya Kitagawa, Roger J. Laham, Masahiro Jinzaki, John Hoe, Frank J. Rybicki, Arthur J. Scholte, Narinder Paul, Swee Yaw Tan, Kunihiro Yoshioka, Robert Röhle, Georg M. Schuetz, Sabine Schueler, Maria H Coenen, Viktoria Wieske, Stephan Achenbach, Matthew J. Budoff, Michael Laule, David E. Newby, Marc Dewey,
To determine whether coronary computed tomography angiography (CTA) should be performed in patients with any clinical probability of coronary artery disease (CAD), and whether the diagnostic performance differs between subgroups of patients.
Tópico(s): Advanced X-ray and CT Imaging
2019 - BMJ | BMJ
Bernardo P. de Almeida, André Filipe Vieira, Joana Paredes, Mónica Bettencourt‐Dias, Nuno L. Barbosa‐Morais,
Centrosome amplification (CA) is a common feature of human tumours and a promising target for cancer therapy. However, CA's pan-cancer prevalence, molecular role in tumourigenesis and therapeutic value in the clinical setting are still largely unexplored. Here, we used a transcriptomic signature (CA20) to characterise the landscape of CA-associated gene expression in 9,721 tumours from The Cancer Genome Atlas (TCGA). CA20 is upregulated in cancer and associated with distinct clinical and molecular ...
Tópico(s): Single-cell and spatial transcriptomics
2019 - International Society for Computational Biology | PLoS Computational Biology
Eike Nagel, John P. Greenwood, Gerry P. McCann, Nuno Bettencourt, Ajay M. Shah, Shazia Hussain, Divaka Perera, Sven Plein, Chiara Bucciarelli‐Ducci, Matthias Paul, Mark Westwood, Michael Marber, Wolf-Stefan Richter, Valentina O. Püntmann, Carsten Schwenke, Jeanette Schulz‐Menger, Rajiv Das, Joyce Wong, Derek J. Hausenloy, Henning Steen, Colin Berry,
In patients with stable angina, two strategies are often used to guide revascularization: one involves myocardial-perfusion cardiovascular magnetic resonance imaging (MRI), and the other involves invasive angiography and measurement of fractional flow reserve (FFR). Whether a cardiovascular MRI-based strategy is noninferior to an FFR-based strategy with respect to major adverse cardiac events has not been established.We performed an unblinded, multicenter, clinical-effectiveness trial by randomly ...
Tópico(s): Coronary Interventions and Diagnostics
2019 - Massachusetts Medical Society | New England Journal of Medicine
Nelson Pinho, Luísa Costa Sousa, Catarina F. Castro, Carlos Alberto Conceição António, Marcelo Addas‐Carvalho, W. Ferreira, Ricardo Ladeiras‐Lopes, Nuno Ferreira, Pedro Braga, Nuno Bettencourt, S.I.S. Pinto,
Tópico(s): Cardiovascular Health and Disease Prevention
2019 - Springer Science+Business Media | Cardiovascular Engineering and Technology
Jennifer Mâncio, António S. Barros, Glória Conceição, Guilherme Pessoa-Amorim, Cátia Santa, Carla Bartosch, Wilson Ferreira, Mónica Carvalho, Nuno Ferreira, Luís Vouga, Isabel M. Miranda, Rui Vitorino, Bruno Manadas, Inês Falcão‐Pires, Vasco Gama Ribeiro, Adelino Leite‐Moreira, Nuno Bettencourt,
Background & aims The role of epicardial adipose tissue (EAT) in the pathophysiology of late stage-coronary artery disease (CAD) has not been investigated. We explored the association of EAT volume and its proteome with advanced coronary atherosclerosis. Methods The EPICHEART Study prospectively enrolled 574 severe aortic stenosis patients referred to cardiac surgery. Before surgery, EAT volume was quantified by computed tomography (CT). During surgery, epicardial, mediastinal (MAT) and subcutaneous (SAT) ...
Tópico(s): Circular RNAs in diseases
2019 - Elsevier BV | Atherosclerosis
Adriana Villa, Laura Corsinovi, Ioannis Ntalas, Xenios Milidonis, Cian M. Scannell, Gabriella Di Giovine, Nicholas Child, Catarina Ferreira, Muhummad Sohaib Nazir, Júlia Karády, Esmeralda Eshja, Viola De Francesco, Nuno Bettencourt, Andreas Schuster, Tevfik F. Ismail, Reza Razavi, Amedeo Chiribiri,
Clinical evaluation of stress perfusion cardiovascular magnetic resonance (CMR) is currently based on visual assessment and has shown high diagnostic accuracy in previous clinical trials, when performed by expert readers or core laboratories. However, these results may not be generalizable to clinical practice, particularly when less experienced readers are concerned. Other factors, such as the level of training, the extent of ischemia, and image quality could affect the diagnostic accuracy. Moreover, ...
Tópico(s): Ultrasound and Hyperthermia Applications
2018 - BioMed Central | Journal of Cardiovascular Magnetic Resonance
Nelson Pinho, Catarina F. Castro, Carlos Alberto Conceição António, Nuno Bettencourt, Luísa Costa Sousa, S.I.S. Pinto,
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2018 - Springer Science+Business Media | Medical & Biological Engineering & Computing
Guilherme Pessoa-Amorim, Jennifer Mâncio, Luís Vouga, José Ribeiro, Vasco Gama, Nuno Bettencourt, Ricardo Fontes‐Carvalho,
La disfunción de la aurícula izquierda en la estenosis aórtica puede preceder a la dilatación y predecir la aparición de fibrilación auricular (FA). Para analizar esta hipótesis, se estudió la función auricular izquierda y se determinó su impacto en la incidencia de FA tras recambio valvular aórtico. Se estudió mediante ecocardiografía con speckle-tracking a 149 pacientes (74 ± 8,6 años; el 51% varones) con estenosis aórtica grave sin FA previa. La función auricular izquierda se evaluó con el pico de ...
Tópico(s): Cardiac Arrhythmias and Treatments
2018 - Elsevier BV | Revista Española de Cardiología
Jennifer Mâncio, Diana C. S. Azevedo, Mariana Fragão-Marques, Inês Falcão‐Pires, Adelino Leite‐Moreira, Nuno Lunet, Ricardo Fontes‐Carvalho, Nuno Bettencourt,
Many studies have explored the hypothesis that epicardial adipose tissue (EAT) accumulation adversely affects cardiac remodeling. We assessed, through a systematic review and meta-analysis, whether EAT is linked to left atrial (LA) and left ventricular (LV) structure and function, irrespective of global or abdominal visceral adiposity. We searched MEDLINE, Scopus, and Web of Science for studies evaluating the association of EAT volume quantified by computed tomography with cardiac morphology and function. ...
Tópico(s): Cardiovascular Effects of Exercise
2018 - Elsevier BV | The American Journal of Cardiology
Produção Nacional
Revisado por pares
Ricardo Ladeiras‐Lopes, Henrique Turin Moreira, Nuno Bettencourt, Ricardo Fontes‐Carvalho, Francisco Sampaio, Bharath Ambale‐Venkatesh, Colin O. Wu, Kiang Liu, Alain G. Bertoni, Pamela Ouyang, David A. Bluemke, João A.C. Lima,
The relationship of metabolic syndrome (MetS) and insulin resistance (one of its key pathophysiological mediators) with diastolic dysfunction and myocardial fibrosis is not well understood. This study aimed to evaluate the association of MetS with diastolic function and myocardial extracellular matrix (ECM) using cardiac MRI (CMRI) in a large community-based population. This cross-sectional analysis included 1,582 participants from the Multi-Ethnic Study of Atherosclerosis (MESA) with left ventricular ...
Tópico(s): Advanced MRI Techniques and Applications
2018 - American Diabetes Association | Diabetes