Produção Nacional
Revisado por pares
Ana Filipa Guedes, Filomena A. Carvalho, C. Santos Moreira, J. Braz Nogueira, Nuno C. Santos,
Arterial hypertension patients present stronger erythrocyte–erythrocyte interactions and high levels of γ′ fibrinogen, which compromise microcirculation and increase the cardiovascular risk.
Tópico(s): Cardiovascular Health and Disease Prevention
2017 - Royal Society of Chemistry | Nanoscale
Produção Nacional
Revisado por pares
Ana Filipa Guedes, C. Santos Moreira, J. Braz Nogueira, Nuno C. Santos, Filomena A. Carvalho,
The stronger fibrinogen binding to erythrocytes from EAH patients may lead to erythrocyte aggregation, representing an important cardiovascular risk factor.
Tópico(s): Cardiovascular Health and Disease Prevention
2019 - Royal Society of Chemistry | Nanoscale
Produção Nacional
Revisado por pares
Mariene R. Amorim, William Marciel de Souza, Antonio Carlos Barros, Daniel A. Toledo-Teixeira, Karina Bispo-dos-Santos, Camila L. Simeoni, Pierina Lorencini Parise, Aline Vieira, Julia Forato, Ingra Morales Claro, Luciana Souto Mofatto, Priscilla P. Barbosa, Natália S. Brunetti, Emerson Salvador Sousa França, Gisele Audrei Pedroso, Barbara F.N. Carvalho, Tânia Regina Zaccariotto, Kamila Cristina Silva Krywacz, André Schwambach Vieira, Marcelo A. Mori, Alessandro S. Farias, Maria Helena Postal Pavan, Luís Felipe Bachur, Luis Guilherme Cardoso, Fernando Rosado Spilki, Éster Cerdeira Sabino, Nuno R. Faria, Magnun Nueldo Nunes Santos, Rodrigo Nogueira Angerami, Patrícia Asfora Falabella Leme, Angélica Zaninelli Schreiber, Maria Luíza Moretti, Fabiana Granja, José Luiz Proença‐Módena,
We documented 4 cases of severe acute respiratory syndrome coronavirus 2 reinfection by non-variant of concern strains among healthcare workers in Campinas, Brazil. We isolated infectious particles from nasopharyngeal secretions during both infection episodes. Improved and continued protection measures are necessary to mitigate the risk for reinfection among healthcare workers.
Tópico(s): COVID-19 and Mental Health
2021 - Centers for Disease Control and Prevention | Emerging infectious diseases
Catarina Pereira, Luísa Barreira, Nuno R. Neng, J.M.F. Nogueira, Cátia F. Marques, Tamára Santos, João Varela, Luísa Custódio,
Aromatic halophyte plants are an outstanding source of bioactive compounds and natural products with potential use in the food industry. This work reports the in vitro antioxidant activity, toxicity, polyphenolic profile and mineral contents of infusions and decoctions from stems, leaves and flowers of Crithmum maritimum L., an aromatic and edible maritime halophyte (sea fennel). Aspalathus linearis (Burm.f.) Dahlg. (rooibos) herbal tea was used as a reference. Sea fennel's tisanes, particularly from ...
Tópico(s): Phytochemical and Pharmacological Studies
2017 - Elsevier BV | Food and Chemical Toxicology
Joana Salta, Alice Martins, Rui Galhano dos Santos, Nuno R. Neng, J.M.F. Nogueira, Jorge Justino, Amélia P. Rauter,
The phenolic profile and the antioxidant activity of Rocha pear, a Portuguese pear cultivar, were determined and compared with the commercially available pear varieties Comice, Abate, General Leclerc and Passe Crassane. Phenolic composition of the methanolic extracts of these pears was determined by high performance liquid chromatography with diode array detection (HPLC-DAD), while antioxidant activities were evaluated using three complementary test systems: DPPH radical scavenging activity, ferric ...
Tópico(s): Plant Physiology and Cultivation Studies
2010 - Elsevier BV | Journal of Functional Foods
Marina Baessa, Maria João Rodrigues, Catarina Pereira, Tamára Santos, Nuno R. Neng, J.M.F. Nogueira, Luísa Barreira, João Varela, Haroon Ahmed, Saira Asif, Sofiene Boukhari, Waqas Khan Kayani, Khawaja Shafique Ahmad, Gökhan Zengin, Adriano Mollica, Luísa Custódio,
Infusions, decoctions and tinctures were prepared from flowers of Butea monosperma (Lam.) Taub. and Sesbania grandiflora (L.) Poiret and evaluated for in vitro inhibition of enzymes implicated on the onset of neurological diseases (acetylcholinesterase: AChE and butyrylcholinesterase: BuChE), diabetes (α-glucosidase and α-amylase), obesity (lipase) and skin hyperpigmentation (tyrosinase). Extracts were also appraised for radical scavenging activity (RSA) on 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′- ...
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2018 - Elsevier BV | South African Journal of Botany
Maria João Martins, Ana Margarida Pinto, Paula Castilho, A. Macedo, A.T. Pereira, M. Bajouco, R. Almeida Leite, Ondina Matos, Sofia Morais, Nuno Madeira, Vasco Nogueira, C. Roque, Prazeres Santos, Telma Santos, Tiago Santos, Vítor Santos, Ana Filipa Troia, Célia Barreto Carvalho,
Antipsychotic medication non-adherence is a complex and multifaceted problem that may hinder recovery in psychosis-spectrum disorders. Therefore, it warrants an early and comprehensive assessment. Current self-report measures focus entirely on behavioral and attitudinal barriers to adherence, failing to provide insight about key psychosocial drivers such as shame and stigma that may also account for non-adherence. This study's main goals were to develop a brief scale for measuring antipsychotic ( ...
Tópico(s): Mental Health Treatment and Access
2019 - Elsevier BV | Psychiatry Research
Produção Nacional
Revisado por pares
Flávia Barreto dos Santos, Fernanda B Nogueira, María G. Castro, Priscila CG Nunes, Ana María Bispo de Filippis, Nuno R. Faria, Jaqueline BS Simões, Simone Alves Sampaio, Clarice R Santos, Rita Maria Ribeiro Nogueira,
In Brazil dengue has been a major public health problem since DENV-1 introduction and spread in 1986. After a low or silent co-circulation, DENV-1 re-emerged in 2009 causing a major epidemic in the country in 2010 and 2011. In this study, the phylogeny of DENV-1 strains isolated in RJ after its first introduction in 1986 and after its emergence in 2009 and 2010 was performed in order to document possible evolutionary patterns or introductions in a re-emergent virus. The analysis of the E gene sequences ...
Tópico(s): Vector-borne infectious diseases
2011 - BioMed Central | Virology Journal
Produção Nacional
Revisado por pares
Marta Oliveira, Maria João Rodrigues, Catarina Pereira, Rubens Lima do Monte‐Neto, Policarpo Ademar Santos, Nuno R. Neng, J.M.F. Nogueira, João Varela, Luísa Barreira, Luísa Custódio,
This work reports for the first time the in vitro anti Leishmania infantum activity of acetone and dichloromethane (DCM) extracts from 25 extremophile plants from Southern Portugal. DCM extracts from Inula chritmoides and Spergularia rubra were active against axenic promastigotes and intracellular amastigotes, had anti-inflammatory properties on lipopolysaccharide (LPS)-stimulated macrophages, inhibited acetylcholinesterase and had no haemolytic activity on human erythrocytes. Eleven phenolics were ...
Tópico(s): Cynara cardunculus studies
2017 - Taylor & Francis | Natural Product Research
Gabriel Filipe Satoto, Ana S. Fernandes, Nuno Saraiva, F. J. V. Santos, Nuno R. Neng, J.M.F. Nogueira, Tânia Santos de Almeida, Maria Eduarda Araújo,
Ximenia (Ximenia americana L.) is a shrub, or small tree, native from Africa and spread across different continents. In Angola, the seeds oil is used by local populations, to prevent sunburn, to smooth and hydrate the skin, and to give it a pleasant color and elasticity, to prevent stretch marks, in pregnant woman, and also as hair conditioner. Herein, an oil sold in the region (LPO), and two others extracted in laboratory, from seeds collected in the same region, were investigated in terms of their ...
Tópico(s): Phytochemistry Medicinal Plant Applications
2019 - Multidisciplinary Digital Publishing Institute | Biomolecules
Andreia Noites, Anabela Moreira, Cristina Melo, Maria Fernanda de Oliveira Faria, Rui Vilarinho, Carla Patrícia Freitas, Pedro Monteiro, Paulo Carvalho, Nuno Adubeiro, Manuela Amorim, Luísa Nogueira, Rubim Santos,
Tópico(s): Physical Activity and Health
2016 - Elsevier BV | European Journal of Integrative Medicine
Sofia Brito, Nuno Santos Carneiro, Conceição Nogueira,
The present work intends to analyse how pre-school aged children experience the re/construction of a 'gender identity' and the processes that create it as an essential, factual, and unchangeable reality – therefore, suspect. Given the growing importance of 'gender identity development' in child development literature, as well as the arising voices of 'gender non-conforming' childhoods, this theme seems particularly relevant when faced with the limitations imposed by macrosocial discourses of cisheteronormativity. ...
Tópico(s): Gender, Sexuality, and Education
2021 - Routledge | Ethnography & Education
Liliana Rodrigues, Nuno Santos Carneiro, Conceição Nogueira,
Resumo Neste artigo, apresenta-se um breve enquadramento histórico das abordagens científicas, médicas e psicológicas sobre as transexualidades, tecendo um conjunto de considerações sobre a forma como tal enquadramento foi fundacional da noção de patologia associada às pessoas trans e como tem sido responsável pela manutenção da patologização destes indivíduos no imaginário coletivo. Para atingir tal objetivo, é desenhado um mapa cronológico dos acontecimentos que têm vindo a marcar, ao longo da ...
Tópico(s): African Sexualities and LGBTQ+ Issues
2021 - UNIVERSIDADE DE SÃO PAULO | Saúde e Sociedade
Marta M. Alves, Luísa Marques, Isabel Nogueira, Catarina Santos, Sara B. Salazar, S. Eugénio, Nuno P. Mira, M.F. Montemor,
Zinc (Zn) has been proposed as an alternative metallic biodegradable material to support transient wound-healing processes. Once a Zn piece is implanted inside the organism the degradation will depend upon the physiological surrounding environment. This, by modulating the composition of the surface layers formed on Zn devices, will govern the subsequent interactions with the surrounding living cells (e.g. biocompatibility and/or antifungal behaviour). In silico simulation of an implanted Zn piece ...
Tópico(s): Magnesium Alloys: Properties and Applications
2018 - Elsevier BV | Applied Surface Science
Ricardo Ladeiras‐Lopes, Alexandre Kirchhofer Pereira, Amanda Nogueira, Tiago Pinheiro-Torres, Isabel Pinto, Ricardo Santos-Pereira, Nuno Lunet,
Tópico(s): Diet, Metabolism, and Disease
2008 - Springer Science+Business Media | Cancer Causes & Control
M. C. d'Orey, Mário Mateus, Hercília Guimara ̃es, Cristina Miguel, María José Costeira, Rosete Nogueira, Nuno Montenegro, Norberto T. Santos, P Maroteaux,
Tópico(s): Skin Protection and Aging
1997 - Springer Science+Business Media | Pediatric Radiology
Produção Nacional
Revisado por pares
Teresa Monjardino, Ana Henriques, Carla Moreira, Teresa Rodrigues, Nuno Adubeiro, Luísa Nogueira, Cyrus Cooper, Ana Cristina Santos, Raquel Lucas,
ABSTRACT Weight management strategies during pregnancy reduce child cardiometabolic risk. However, because maternal weight has an overall positive correlation with offspring bone mass, pregnancy weight management could adversely affect child bone health. We aimed to estimate associations between gestational weight gain (GWG) and bone mineralization in the offspring at 7 years of age, and test early pregnancy body mass index (BMI) as an effect modifier. We analyzed prospective data from 2167 mother- ...
Tópico(s): Bariatric Surgery and Outcomes
2018 - Oxford University Press | Journal of Bone and Mineral Research
Produção Nacional
Revisado por pares
Mariana Sequetin Cunha, Nuno R. Faria, Giovana Santos Caleiro, Darlan Silva Candido, Sarah C. Hill, Ingra Morales Claro, Antônio Charlys da Costa, Juliana Silva Nogueira, Adriana Yurika Maeda, Fernanda Gisele da Silva, Renato Pereira de Souza, Roberta Spínola, Rosa Maria Tubaki, Regiane Maria Tironi de Menezes, Leandro Abade, Luís Filipe Mucci, María do Carmo Sampaio Tavares Timenetsky, Esther Cerdeira Sabino,
The southeastern region of Brazil has recently experienced the largest yellow fever disease outbreak in decades. Since July 2016 epizootic events were reported in São Paulo state's north region, where 787 Culicidae were captured as part of public health surveillance efforts and tested using real-time quantitative PCR. One Aedes scapularis pool collected in November 2016 in an agriculture area in Urupês city tested positive for YFV-RNA. Using a validated multiplex PCR approach we were able to recover ...
Tópico(s): Viral Infections and Vectors
2020 - Elsevier BV | Acta Tropica
Isabel Oliveira, Cíntia Oliveira, Juliana da Silva Nogueira Carvalho, Nuno Rebelo dos Santos, Ana Torres,
Enquadramento: a violência doméstica é um problema de saúde pública. O enfermeiro de família, enquanto contacto privilegiado com mulheres e famílias, pode desempenhar um papel relevante na abordagem à mulher vítima de violência. Objetivo: identificar os conhecimentos, atitudes e barreiras dos enfermeiros de família na abordagem às mulheres vítimas de violência doméstica. Metodologia: desenho quantitativo, exploratório, descritivo e transversal, numa amostra não probabilística por conveniência, constituída ...
Tópico(s): Male Reproductive Health Studies
2020 - | Revista de Investigação & Inovação em Saúde
Viana Castañeda-Loaiza, Marta Oliveira, Tamára Santos, Lisa Schüler, Alexandre R. Lima, Florinda Gama, Miguel Salazar, Nuno R. Neng, J.M.F. Nogueira, João Varela, Luísa Barreira,
Some halophyte plants are currently used in gourmet cuisine due to their unique organoleptic properties. Moreover, they exhibit excellent nutritional and functional properties, being rich in polyphenolics and vitamins. These compounds are associated to strong antioxidant activity and enhanced health benefits. This work compared the nutritional properties and antioxidant potential of three species (Mesembryanthemum nodiflorum, Suaeda maritima and Sarcocornia fruticosa) collected in saltmarshes from ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2020 - Elsevier BV | Food Chemistry
Produção Nacional
Revisado por pares
Jéssica Franzon Cruz do Espirito Santo, Caique Z. Kirilo, Marcelo Nogueira, Nuno Santos, Ricardo J. Machado, Luiz Carlos Machi Lozano, Álvaro André Colombero Prado, Juliana Vieira de Carvalho,
In an effort to reduce the crises of people with autism spectrum disorder and increase their safety, a study was conducted on home automation so that, through a medical protocol, it will be possible to configure situations and actions that should be put into practice when the system identifies that the autistic stress level is high. In addition, some studies were necessary to understand how the autistic mind works, based on the literature and interviews with specialists in the field. Through the ...
Tópico(s): Language Acquisition and Education
2021 - Springer Science+Business Media | Lecture notes in computer science
Produção Nacional
Revisado por pares
Jaqueline Góes de Jesus, Karina Rocha Dutra, Flavia Cristina da Silva Sales, Ingra Morales Claro, Ana Carolina Bernardes Terzian, Darlan da Silva Cândido, Sarah C. Hill, Julien Thézé, Celeste Torres, Tatiana Lang D’Agostini, Alvina Clara Félix, Alessandra Reis, Luíz Carlos Júnior Alcântara, André Luiz de Abreu, Júlio HR Croda, Wanderson Kleber de Oliveira, Ana Maria Bispo de Filipis, Maria do Carmo Rodrigues dos Santos Camis, Camila Malta Romano, Nicholas J. Loman, Oliver G. Pybus, Éster Cerdeira Sabino, Maurício Lacerda Nogueira, Nuno R. Faria,
BACKGROUND Despite efforts to mitigate the impact of dengue virus (DENV) epidemics, the virus remains a public health problem in tropical and subtropical regions around the world. Most DENV cases in the Americas between January and July 2019 were reported in Brazil. São Paulo State in the southeast of Brazil has reported nearly half of all DENV infections in the country. OBJECTIVES To understand the origin and dynamics of the 2019 DENV outbreak. METHODS Here using portable nanopore sequencing we ...
Tópico(s): Insect symbiosis and bacterial influences
2020 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Ana Figueiredo, Maria Amélia Almeida, Teresa Almodôvar, Paula M. Alves, António Araújo, D. Morchón Araujo, Fernando Barata, Lourdes Barradas, Ana Barroso, U Brito, E. Camacho, Dolores Canário, T Cardoso, A. Chaves, Luís Costa, J. Cunha, J Duarte, F. Estevinho, M. Felizardo, João Paulo S. Fernandes, L. Ferreira, L. Ferreira, Paula Fidalgo, Carolina Saliba de Freitas, P. Garrido, Nuno Gil, Direndra Hasmucrai, Eduarda Eugênia Dias de Jesus, José António Lopes, Joana Martins‐Macedo, A. Meleiro, R. Nêveda, Fábio César Sousa Nogueira, M. Pantorotto, B. Parente, Alice Pêgo, Maria João Rocha, João Roque, Carlos Roberto dos Santos, João Tomé Saraiva, Eike Lawrence Nascimento Soares e Silva, S. Silva, Sérgio Simões, Michellia Pereira Soares, E. Teixeira, T. Timóteo, Venceslau Hespanhol,
The main aim of the study was to evaluate the efficacy and safety profile of Nivolumab, an immune-checkpoint-inhibitor antibody, in advanced, previously treated, Non-Small Cell Lung Cancer (NSCLC) patients, in a real world setting. We performed a retrospective, multicentre data analysis of patients who were included in the Portuguese Nivolumab Expanded Access Program (EAP). Eligibility criteria included histologically or citologically confirmed NSCLC, stage IIIB and IV, evaluable disease, sufficient ...
Tópico(s): Lung Cancer Diagnosis and Treatment
2019 - Elsevier BV | Pulmonology
Renato dos Santos, Ângelo Rocha, Ana A. Matias, Catarina M.M. Duarte, Isabel Sá‐Nogueira, Nuno M. T. Lourenço, João Paulo Borges, Pedro Vidinha,
We report a method to obtain electrospun fibers based on ionic liquids and gelatin, exhibiting antimicrobial properties.
Tópico(s): Microplastics and Plastic Pollution
2013 - Royal Society of Chemistry | RSC Advances
Nuno Cabanelas, Mário Oliveira, Manuel Nogueira da Silva, Pedro Silva Cunha, Bruno Valente, Ana Lousinha, Sofia Santos, Luísa Moura Branco, Rui Cruz Ferreira,
The demonstrated benefits of cardiac resynchronization therapy (CRT) in reducing mortality and hospitalizations for heart failure, improving NYHA functional class and inducing reverse remodeling have led to its increasing use in clinical practice. However, its potential contribution to complex ventricular arrhythmias is controversial. We present the case of a female patient with valvular heart failure and severe systolic dysfunction, in NYHA class III and under optimal medical therapy, without previous ...
Tópico(s): Neurological disorders and treatments
2014 - Elsevier BV | Revista Portuguesa de Cardiologia (English Edition)
Nuno V. Álvaro, Francisco Wallenstein, Ana I. Neto, Euler Melo Nogueira, Jéssica Ferreira, Catarina I. Santos, A. F. Amaral,
Sampling benthic communities usually requires intensive field and lab work which is generally performed by skilled staff. In algal dominated communities, like those on the shores of the Azores, biotope characterization studies focused on the more conspicuous algae categories, thus reducing the skills required for species identification. The present study compares in situ quadrat quantifications done by a skilled reader, with computer based quadrat quantifications using digital photographic records ...
Tópico(s): Coral and Marine Ecosystems Studies
2007 - Springer Science+Business Media | Hydrobiologia
Daniel Pereira da Silva, Cristina Nogueira‐Silva, Jorge Lima, António Braga, J Saraiva, Fernanda Águas, Nuno Nogueira-Martins, Susana Santo, José Furtado, Maria do Céu Almeida, Cristina Guerreiro, Carlos Veríssimo, João Bernardes,
The demographic and professional characteristics of specialists in Obstetrics and Gynecology registered in Portugal are presented and current and future needs assessed.An analysis of the data from Instituto Nacional de Estatística, Ordem dos Médicos and a survey sent to the directors of the departments of Obstetrics and Gynecology of Portuguese hospitals was perfomed. In order to calculate the necessary number of specialists, established indicators of the activity of the specialty were used.In 2018, ...
Tópico(s): Global Health Care Issues
2022 - Ordem dos Médicos | Acta Médica Portuguesa
Ana Helena Barbosa Fachada, Joana Aidos, Joana Santos, Nuno Nogueira Martins,
Introduction: Laparoscopic female sterilization (LFS) is a surgical procedure that permanently prevents pregnancy by total occlusion of the fallopian tubes. The first case was performed in Switzerland by Bösch in 1936, and it is the most used method to provide definitive contraception to women. The main indication is patient's desire and the few contra-indications include: the patient is unable to understand its intended permanence; a medical condition requiring hysterectomy or bilateral oophorectomy; ...
Tópico(s): Gynecological conditions and treatments
2019 - Elsevier BV | European Journal of Obstetrics & Gynecology and Reproductive Biology
Produção Nacional
Revisado por pares
Gabriel de A. Batista, Marcelo Nogueira, Nuno Santos, Ricardo J. Machado,
Skin cancer is the most common among all cancers and its early diagnosis increases the patient's chances of healing. One of the ways to make this diagnosis is through dermatoscopy. Dermatoscopy is a technique that consists of recognizing structures present in the skin, not visible to the naked eye. Therefore, for assisting the use of dermatoscopy by health professionals, this work presents a device to support skin cancer recognition using the histogram of oriented gradients and machine learning, ...
Tópico(s): Video Surveillance and Tracking Methods
2020 - Springer Science+Business Media | Lecture notes in computer science
Produção Nacional
Revisado por pares
Igor Braga, Marcelo Nogueira, Nuno Santos, Ricardo J. Machado,
Tópico(s): Digital Transformation in Industry
2020 - Springer Science+Business Media | Lecture notes in computer science