Limpar
118.219 resultados

Acesso aberto

Tipo do recurso

Tipo de base de dados

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Artigo Acesso aberto Revisado por pares

Meizi Liu, Ran An, Zitong Wu, Leping Dai, Qiaomiao Zeng, Wenfeng Chen,

Background: Oral mucositis (OM) is a common and severe side effect of radiotherapy in head and neck cancer (HNC). The study aimed to investigate the longitudinal changes in OM and its influencing factors in patients with HNC ... patients with HNC undergoing radiation therapy were enrolled. OM, oral hygiene, oral infections, oral pain, feeding route, ... measured at 7 times. The influencing factors of OM were analyzed using generalized estimation equations (GEEs). Results: ... included in this study. The prevalence of severe OM at T0, T1, T2, T3, T4, T5, and ...

Tópico(s): Dysphagia Assessment and Management

2024 - SAGE Publishing | Ear Nose & Throat Journal

Livro
4. Om

Alexander Street

Artigo Acesso aberto Revisado por pares

Ziwei Lan, Fengbo Tan, Jialin He, Jianyang Liu, Ming Lu, Zhiping Hu, Yi Zhuo, Junjiang Liu, Xiangqi Tang, Zheng Jiang, Aojie Lian, Yongheng Chen, Yan Huang,

... properties of olfactory mucosa-derived mesenchymal stem cells (OM-MSCs) in intracerebral hemorrhage. Yet, the potential neuroprotective capacity of curcumin-pretreated OM-MSCs (CUR-OM-MSCs) on reducing PANoptotic neuronal death during cerebral ... enhanced the proliferation and anti-inflammatory capacity of OM-MSCs. The CUR-OM-MSCs group experienced a more pronounced reduction in ... a better recovery of neurological function than the OM-MSCs group. Bioinformatic analysis revealed that microRNA-423- ... 423-5p) expression was obviously upregulated in CUR-OM-MSCs compared to OM-MSCs. CUR-OM-MSCs ...

Tópico(s): Curcumin's Biomedical Applications

2024 - Elsevier BV | Phytomedicine

Periodico Acesso aberto Revisado por pares

Directory of Open Access Journals (DOAJ)

Artigo Acesso aberto Revisado por pares

Amit Saraf, Rohan Gurjar, Swarnendu Kaviraj, Aishwarya Kulkarni, Durgesh Kumar, Ruta Kulkarni, Rashmi G. Virkar, Jayashri Krishnan, Anjali Yadav, Ekta Baranwal, Ajay Singh, Arjun Raghuwanshi, Praveen Agarwal, Laxman Savergave, Sanjay Singh, Himanshu Pophale, Prakash Shende, Ravindra Baban Shinde, Vikram B Vikhe, Abhishek Karmalkar, B. T. Deshmukh, Krishna Giri, Shrikant Deshpande, Ajay Bulle, Md Sabah Siddiqui, Swapnav Borthakur, Venkateswara Reddy Tummuru, Aparna Rao, Dhaiwat Shukla, Manish Kumar Jain, Pankaj Bhardwaj, Pravin Dinkar Supe, Manoja Kumar Das, Manoj Lahoti, Vijaykumar Bhagwan Barge,

... 529), monovalent, thermostable, self-amplifying mRNA vaccine, GEMCOVAC-OM, when administered intradermally as a booster in healthy ... doses of BBV152 or ChAdOx1 nCoV-19. GEMCOVAC-OM was well tolerated with no related serious adverse ... phase 2, the safety and immunogenicity of GEMCOVAC-OM was compared with our prototype mRNA vaccine GEMCOVAC- ... anti-spike (BA.1) IgG antibodies with GEMCOVAC-OM ( P < 0.0001) and GEMCOVAC-19 ( P < 0. ... primary endpoint) and seroconversion were higher with GEMCOVAC-OM ( P < 0.0001). In phase 3, GEMCOVAC-OM ...

Tópico(s): Animal Virus Infections Studies

2024 - Nature Portfolio | Nature Medicine

Artigo Acesso aberto Revisado por pares

Marcelo Bonomi, Dukagjin M. Blakaj, Rafi Kabarriti, Kyle Colvett, Vinita Takiar, Matthew C. Biagioli, Voichita Bar‐Ad, Sharad Goyal, Brian C. Muzyka, Kenneth J. Niermann, Nacer Abrouk, Bryan Oronsky, Tony Reid, Scott Caroen, Stephen T. Sonis, David J. Sher,

... Drug Administration-approved intervention exists for oral mucositis (OM) from chemoradiotherapy (CRT) used to treat head and ... directed molecule that affects key pathways involved in OM pathogenesis. This phase 2a, multi-institutional trial was ... patients treated with CRT alone. Trained evaluators assessed OM using a standardized data collection instrument twice weekly during treatment and then until resolution. OM severity was scored centrally using World Health Organization ... cohorts appeared to demonstrate a similar or lower OM duration relative to control; arm 1 had the ...

Tópico(s): Cancer Diagnosis and Treatment

2023 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics

Artigo Acesso aberto Revisado por pares

Nakajohn Thewasano, Edward M. Germany, Yuki Maruno, Yukari Nakajima, Takuya Shiota,

The outer membrane (OM) of gram-negative bacteria is populated by various outer membrane proteins (OMPs) that fold into a unique β-barrel transmembrane domain. Most OMPs are assembled into the OM by the β-barrel assembly machinery (BAM) complex. ... the development of new antibiotics. The outer membrane (OM) of gram-negative bacteria is populated by various ... transmembrane domain. Most OMPs are assembled into the OM by the β-barrel assembly machinery (BAM) complex. ... antibiotics. Gram-negative bacteria contain an outer membrane (OM), a permeable barrier, and an inner (cytoplasmic) membrane. ...

Tópico(s): Enzyme Structure and Function

2023 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Spyros Angelopoulos, Elliot Bendoly, Jan C. Fransoo, Kai Hoberg, Carol Xiaojuan Ou, Antti Tenhiälä,

... digital technologies across all aspects of operations management (OM) has enabled shifts in decision making, shaping new ... associated scholarly discussions in information systems (IS) and OM span digital manufacturing (e.g., Roscoe et al., 2019), the digitalization of OM and supply chain management (e.g., Holmström et ... are increasingly treated in both the IS and OM literature as an ongoing process rather than an ... widely adopted definitions of DT in IS and OM (e.g., Vial, 2019), as well as from ... we characterize the specific role of DT in OM as follows: through DT endeavors, digital technologies have ...

Tópico(s): Quality and Supply Management

2023 - Wiley | Journal of Operations Management

Jornais Acesso aberto

Frontmatter: Om O-Aminobenzolsulfonsyreamid, Derivat till Densamma Och Om Diazsulfoninföreningar. Essay: O-Aminobenzolsulfonsyran Framställdes Först Af Limpricht Och Berndsen ...

1902 - Gale Group | NCCO SciTechMed 2 of 2

Artigo Acesso aberto Revisado por pares

Tinkara Tinta, Zihao Zhao, Barbara Bayer, Gerhard J. Herndl,

... largely overlooked source of labile organic matter (jelly-OM) in the ocean, characterized by a high protein ... biogeochemical models, the interactions between microbes and jelly-OM have yet to be fully characterized. We conducted jelly-OM enrichment experiments in microcosms to simulate the scenario ... on the metabolic network operated by the jelly-OM degrading bacterial consortium.Our analysis revealed that OM released during the decay of jellyfish blooms triggers ... amino acid catabolism-related enzymes in the jelly-OM degrading community dominated by Pseudoalteromonadaceae, Alteromonadaceae and Vibrionaceae, ...

Tópico(s): Metabolomics and Mass Spectrometry Studies

2023 - BioMed Central | Microbiome

Jornais Acesso aberto

Frontmatter: Några Ord Om Körtelinnervationer Och Körtelkapillarer Hos Lepidopterlarver Samt Om Ett Egendomligt Muskelslag Hos Dessa Senares Sfinkterbildningar Ett Förelöpande Meddelande. Essay: Under ...

1893 - Gale Group | NCCO-STM 1of2

Artigo Acesso aberto Revisado por pares

M. R. Raven, Peter W. Crockford, Malcolm S.W. Hodgskiss, Timothy W. Lyons, Christopher J. Tino, Samuel M. Webb,

... rocks generally contain low concentrations of organic matter (OM), there are key exceptions to this rule, including the relatively OM-rich Arctic Bay shales from Baffin Island, Canada ( ... Basin, ∼1.05 Ga). The mechanisms driving elevated OM concentrations in these and other Proterozoic shales remain ... sulfurization can be a major driver of enhanced OM burial across a range of redox conditions comparable ... we evaluate the role of sulfurization in driving OM preservation in the Mesoproterozoic Borden Basin and discuss ...

Tópico(s): Geochemistry and Elemental Analysis

2023 - Elsevier BV | Geochimica et Cosmochimica Acta

Jornais Acesso aberto

Frontmatter: Om Betydelsen Af Lefvande Kraftens Princip for Frågan Om Dynamiska Systems Stabilitet. Essay: Till En Stor Grupp Af ...

1887 - Gale Group | NCCO-STM 1of2

Artigo Revisado por pares

Chan Lu, Qin Li, Zipeng Qiao, Yanling Liu, Faming Wang,

... evidence linking outdoor air pollution with otitis media (OM), the role of air pollutant(s) exposure during which critical window(s) on childhood OM remains unknown.We sought to identify the key ... associated with the onset and recurrent attacks of OM in kindergarten children.A combined cross-sectional and ... IDW) method. The relationship between air pollution and OM in kindergarten children was studied using multiple logistic regression models.Childhood lifetime OM was associated with PM2.5, SO2 and NO2, ...

Tópico(s): Noise Effects and Management

2023 - Elsevier BV | Journal of Hazardous Materials

Revisão Revisado por pares

Chuan Cai, Jingong Cai, Huiming Liu, Xuejun Wang, Xiang Zeng, Yongshi Wang,

... mudstones implies the association between sedimentary organic matter (OM) and clay minerals. However, the traditional classification of OM, including insoluble kerogen and soluble OM (SOM), ignores the role of minerals, significantly limiting the understanding of the role of mineral-OM interactions in OM preservation and evolution. This paper reviews the mineral and OM characteristics and their relationship in argillaceous sediments and rocks and classifies sedimentary OM into three forms of occurrence, namely free SOM ( ...

Tópico(s): Methane Hydrates and Related Phenomena

2023 - Elsevier BV | Chemical Geology