Limpar
37.840 resultados

Acesso aberto

Tipo do recurso

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Jornais Acesso aberto

From Patrick Brogan, By Tim Albert, By Henry Stanhope Defence Correspondent, By George Clark Political Correspondent, By Our Political Staff, By Hugh Clayton, By Christopher Warman Local Government Correspondent, By Christopher Thomas Labour Reporter, By a Staff Reporter, From Peter Godfrey, From Penny Symon, By Robin Young, From Trevor Fishlock, From Our Correspondent, By Peter Evans Home Affairs Correspondent, By Arthur Reed Air Correspondent, By Our Local Government Correspondent, By Our Education Correspondent, By Our Health Services Correspondent, By Pat Healy Social Services Correspondent, By Peter Waymark Motoring Correspondent, By Robert Parker, By Craig Seton, By Our Agricultural Correspondent, By Pearce Wright Science Editor, By Michael Baily Transport Correspondent, By Our Labour Staff, By John Roper Health Services Correspondent, By Our Social Services Correspondent, By Diana Geddes Education Correspondent, From Michael Hornsby, From Our Own Correspondent, From William Chislett, From Harry Debelius, By Roger Berthoud, From Frank Vogl, From Charles Hargrove, From Robert Fisk, From Michael Knipe, From Moshe Brilliant, From Kuldip Nayar, From Juan de Onis, By Geraldine Norman Sale Room Correspondent, Dan van der Vat, Frank Vogl, By John Woodcock cricket Correspondent, By John Blunsden, By a Special Correspondent, By Michael Phillips Racing Correspondent, By Peter Ryde Golf Correspondent, By John Nicholls, David Robinson, Joan Chissell, Paul Griffiths, Irving Wardle, Stanley Sadie, Ned Chaillet, Paul Moor, Bernard Levin, Michael Shanks, Patrick O'Leary, PHS, William Frankel, TREVOR HUDDLESTON CR, , HAROLD LOCKLEY, , A KENNETH SNOWMAN, , MICHAEL LATHAM, , D. WEDGWOOD, , E. A. BEET, , CARR OF HADLEY, , PETER LILLEY, , OLGA FRANKLIN, , ERIC WINTER, , GORDON McLENNAN, , L. J. BRUCE-CHWATT, , MARY WHITEHOUSE, , JIM SPICER, , EZRA RACHLIN, , By Robin young Consumer Affairs Correspondent, Sir Desmond Heap writes:, By Malcom Brown, By Nicholas Hirst, By Roger Vielvoye, By Our Financial Staff, By Richard Allen, By Derek Harris Commercial Editor, By Clifford Webb, By Arthur Reed, M. E. CORBY, , BERNARD T. CROFT, , PATRICIA COALES, , KENNETH BROWN, , BY THE FINANCIAL EDITOR, By Victor Felstead, By John Brennan, By Christopher Wilkins, By Ashley Druker, By Alison Mitchell, By Michael Clark, Gerald Ely, Henry Stanhope Defence Correspondent, Henry Stanhope, Arthur Reed Air Correspondent, H.S., A.R., Arthur Reed, Charles Gilson defence editor Flight International, Diana Patt,

... Jonathan Swift Gulliver's Travels (u) General release Orca (a) ABC Shaftesbury Avenue Alice in Wonderland (x) ...

1977 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Zhen Shen, Supriya G. Prasanth,

... that a WD repeat containing protein ORC-associated (ORCA/LRWD1) stabilizes the ORC on chromatin and facilitates pre-RC assembly. Further, ORCA levels are cell cycle-regulated, with highest levels ... remains to be elucidated. We now demonstrate that ORCA is polyubiquitinated in vivo, with elevated ubiquitination observed at the G(1)/S boundary. ORCA utilizes lysine-48 (K48) ubiquitin linkage, suggesting that ORCA ubiquitination mediates its regulated degradation. Ubiquitinated ORCA is re-localized in the form of nuclear ...

Tópico(s): Cancer-related Molecular Pathways

2012 - Taylor & Francis | Cell Cycle

Jornais Acesso aberto

Giles Smith, Andrew Robson, Gabriele Marcotti, David Adams, Joanna Hunter, Christian Buckley Industrial Editor, Andrew Pierce, DJM, Neelam Verjee, Paul Wright, Frances Gibb Legal Editor, B. Solloway, Peter Lansley, Paul Hoggart, Mark Souster, Richard Hobson, Ivo Tennant, Michael Evans Defence Editor, Philip Howard, David Chater, James Bone, Clive Davis, Alexandra Frean Social Affairs Correspondent, Richard Hobson One-Day Cricket Correspondent, Mark Henderson Science Correspondent and Jennifer Pollard, Dr Jonathan Romain Maidenhead Synagogue, Sam Lister and Jenny MacArthur, Geoff Brown, David Sharrock, Ben Webster Transport Correspondent, Pat Gibson, David McVay, Briony Fullenough, Donald Hutera, Robert Gore-Langton, John Denny, Jack Malvern, Dominic Walsh, Ruth Gledhill, Richard Nice, Hilary Weale, Patrick Marmion, Jill Dupleix, Angela Jameson Industrial Correspondent, Ruth Gledhill Religion Correspondent, Jill Prime, Robin Young, Stephen Farrell, Chris French, Jenny MacArthur, David Charter and Adam Fresco, Roland Watson, Alexandra Blair and David Charter, Richard Lloyd Parry, David Hands, Ron Lewis, Stefanie Marsh, Mark Easton, David Charter, Simon Winkworth, Angela Jameson, Simon Tait, Clem Cecil and Richard Beeston, Julia Woodger, Elizabeth, Leyla Sanai, Oliver Kay, John Westerby, Joan Jones, Rick Broadbent, Tim Cooper, Jan Davidson, Philip Arestis (Director of Research, Cambridge Centre for Economic & Public Policy). Gwyneth Dunwoody (Labour MP for Crewe and Nantwich), Caroline Lucas (Green MEP for South-East England), Vince Mills (Director, Trade Union Research Centre, Glasgow Caledonian University), Mark Seddon (Labour Party NEC), Eryl Parry, Gabriel Rozenberg, Neil Harman Tennis Correspondent, Raymond Keene, Adam Sage, Peter M. Richardson, Christine Buckley Industrial Editor, Xan Rice, Jeremy Page, Elizabeth Judge and Rory Watson, Helen Nugent, Christopher Martin-Jenkins Chief Cricket Correspondent, Mick Hume, Roger Boyes, David Mattin, Oliver August, Nick Hasell, David Hands Rugby Correspondent, Tom Dart, William Rees-Mogg, Bruce Beveridge, Amrit Dhillon, Jane Shilling, Tim Hames, Mel Webb, Ian Johns, Brenda Brissenden, Elizabeth Judge and Christine Seib, George Caulkin, Neil Fisher, Ingrid Mansell, Alan Lee, Michael Austin, J. M. L. Stone, Jenny Davey and Elizabeth Judge, David Charter Chief Political Correspondent, David Sinclair, Martin Waller, Chris Ayres, Andrew Stevenson, Producer-director of The Illuminati, Robin Cole-Hamilton, Benedict Nightingale, Angus Batey, Dr Thomas Stuttaford, Stephen Dalton, Ellis Bacon, Richard Morrison, Alyson Rudd, Andrew Fairweather-Tall, Bill Edgar, Keith Fairweather, Roy Salter, S. J. Exeter, Sebastian Smith, Chris Loughran (Consultant radiologist), Kjell Jonevret, Peter Klinger, Christopher Irvine, V. A. Dunn,

... The Times Postcomm chief's compensation challenge Analysis Orca plans sell-off from Emblaze Lloyds TSB Royal ...

2004 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Zhen Shen, Arindam Chakraborty, Ankur Jain, Sumanprava Giri, Taekjip Ha, Kannanganattu V. Prasanth, Supriya G. Prasanth,

... repeat-containing protein, origin recognition complex (ORC)-associated (ORCA/LRWD1), plays a crucial role in stabilizing ORC to chromatin. Here, we find that ORCA is required for the G(1)-to-S- ... human cells. In addition to binding to ORC, ORCA associates with Cdt1 and its inhibitor, geminin. Single-molecule pulldown experiments demonstrate that each molecule of ORCA can bind to one molecule of ORC, one ... of Cdt1, and two molecules of geminin. Further, ORCA directly interacts with the N terminus of Orc2, ...

Tópico(s): RNA Research and Splicing

2012 - Taylor & Francis | Molecular and Cellular Biology

Jornais Acesso aberto

Giles Smith, Andrew Robson, Amanda Andrews, James Christopher Chief Film Critic, Sam Wardill, Phil Yates, Christina Hardyment, Vivian Russell, Charles Scanlan, Dwight Longenecker, Robert Cole, Mrs M I Postlethwaite, Matthew Syed, Neelam Verjee, Caroline Stacey, Nick Broomfield, Louise Roddon, David Aaronovitch, Amanda Ursell, Simon Barnes, Brian Martelli, Jane MacQuitty, James Harding, Simon Hills, Paul Hoggart, Aidan Hartley, Mark Frary, John Mulvey, Clare Lazaro, Tony Turnbull, Brian Davies, Philip Howard, Hannah Betts, Carol Midgley, Sarah Dunn, B. L. Pooley, David Chater, Angela Court, Kate Wighton, Joanna Bale, James Bone, Michael Binyon, Melissa Katsoulis, Clive Davis, Richard Hobson One-Day Cricket Correspondent, Elizabeth Judge, Keith Nolan, Gabrielle Starkey, Lucia Van Der Post, Bob Stanley, Dean Temple, Graham Stewart, Martin Aston, Sam Marlowe, Wendy Ide, John Bungey, Philip Parkin General Secretary, Geoff Brown, Lucy Bannerman, Gerald Davies, Chris Sullivan, Andrew Norfolk, Robin Pagnamenta, Rosie Millard, Giles Coren, Vivienne Parry, Charlotte Vincent Director, Nancy Durrant, Stephen McClarence, Jane MacArtney, Vinny Lee, Valerie Elliott, Siobhan Kennedy, Tyler Wetherall, Jack Malvern, Tom Bawden, Dominic Walsh, Dan Sabbagh Media Editor, Debra Craine, Gary Jacob, Les Webb, Mike Pattenden, Tom Charity, Allan Simmons, Dr Jane Collins, Tim Reid, Daniel Finkelstein, Jeanette Winterson, Roy Henderson, Dalya Alberge Arts Correspondent, Robert Harris, Tom Gatti, Richard Ford Home Correspondent, Jo Morris, Phoebe Greenwood, Alan Hamilton, Peter Millar, Norah Jones, Ben Machell, Nick Wyke, Michael Burnside, Juliette Kellow, Nicholas Dobson, Dakar Rally, Valerie Elliott Consumer Editor, Tina Gaudoin, Jon Lusk, Charles Bremner, Mi Postlethwaite, Jonathan Richards, Martin Symington, Helen Rumbelow, Liz Chong, Lucy Sweeney, Tim Teeman, Hugo Rifkind, Rosemary Summerfield, Derwent May, Kate Muir, Theo Wells, Paula Hawkins, Nigel Williamson, Daniel McGrory, Ed Potton, Oliver Kay, Gerard Baker, Oleg Gordievsky, Stephen Anderton, Amber Cowan, Sarah Vine, Mark Atherton, Lisa Armstrong, Jenny Lewis, Jane Wheatley, James Harding Business Editor, Rick Broadbent, Tom Baldwin, Jonathan Clayton Africa Correspondent, Morgan Falconer, Chris Power, GrÁinne Gilmore Deputy Personal Finance Editor, Sally Baker, Lily Tomlin, Pete Paphides, Ann Treneman, Rob Yorke, Simon de Bruxelles, Rob Wright, ZoË Strimpel, Christina Koning, Magnus Grimond, Christine Holt, Neil Harman Tennis Correspondent, David Powell Athletics Correspondent, Raymond Keene, Suzi Godson, Kate Saunders, John Russell Taylor, Ron Lee, Richard Brass, Matt Hughes, Rebecca O'Connor, Selina Scott, Gordon Ramsay, Lesley Falconer, Kaveh Solhekol, Nigel Hawkes, Rick Jones, Peta Bee, Andrew G. Marshall, Burhan Wazir, Chris Campling, M. M. Allan, Laura Deeley, Damian Whitworth, Marcus Leroux, Rebecca O'connor, ChloË Bryan-Brown, Ross Leckie, James Charles, Peter Dixon, Nick Hasell, Thomasina Miers, Chloë Bryan-Brown, Graham Searjeant Personal Investor, Margaret Reynolds, David Hands Rugby Correspondent, Kevin Maher, Paul Simons, Adam Fresco, Nicholas Clee, Caroline Flint Minister for Public Health, Nigel Kendall, Anne Ashworth, Joanna Pitman, Muir Vidler, Philip Webster Political Editor, Robert Crampton, Jane Shilling, Philippa Pearce, Tim Hames, Nigel Macnicol, Ian Johns, Dominic Maxwell, Anthony Browne Chief Political Correspondent, Matthew Parris, Virginia Blackburn, Jennai Cox, Thomas Catan, Amanda Craig, John Staples, George Caulkin, Angela Neustatter, Russell Jenkins, Caitlin Moran, Neil Fisher, Iain Finlayson, Peter Riddell, Ben MacIntyre, Bess Twiston Davies, Rob Nash, Philip Webster, Pauline Rowson, David Sanderson, Matthew Dennison, John Naish, The Rev Dr Nigel Scotland, Martin Waller, Chris Ayres, Michael Horsnell, Giles Foden, James Jackson, Carl Mortished International Business Editor, Nigel Hawkes Health Editor, Sarah Butler, Ashling O'Connor, Benedict Nightingale, Charlotte Phillips, Jane Fearnley, Anna Shepard, Christopher Andrew, Louise Cohen, Angus Batey, Dr Thomas Stuttaford, Jill Crawshaw, Stephen Dalton, John (Jeremy Robert) Naish, Adrian Milledge, Tim Lawson-Cruttenden, Tom Chesshyre, Tony Halpin, Alice Miles, Philip Nelson, Richard Morrison, Adam Sherwin, James Christopher, Michael Evans, Lucy Cowan, Cath Urquhart Travel Editor, Olav Bjortomt, Stephen DAlton, Will Hide, John Caton, Daphne Lockyer, David Robertson, India Knight, Bryce Elder, Elizabeth Judge Telecoms Correspondent, Donny Tourette,

... on renewed bid rumours Large caps Suitor boosts Orca Interactive Small caps Gilts Why savers, too, could ...

2007 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Bea Pauw, Frédérique Hilliou, Virginia Martin, Guillaume Chatel, Cocky J.F. de Wolf, Antony Champion, Martial Pré, Bert van Duijn, Jan W. Kijne, Leslie van der Fits, Johan Memelink,

... yeast extract; STR, strictosidine synthase; TDC, tryptophan decarboxylase; ORCA, octadecanoid-responsive Catharanthus AP2 domain; AP2, APETALA2; ERF, ... 129-136Crossref PubMed Scopus (38) Google Scholar). The ORCA transcription factors 2J. Memelink, unpublished results. or the ... in a ratio of 1:4 (GUS:ZCT/ORCA). In the case of co-bombardment with both ORCA and zinc finger cDNAs, the ratio was 1:4:4 (GUS:ZCT:ORCA). Each plasmid combination was bombarded in triplicate, where ... growth on medium lacking histidine. No cDNAs encoding ORCA or CrBPF1 proteins were recovered, which is consistent ...

Tópico(s): Plant and fungal interactions

2004 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Wen‐Liang Dong, J. H. van Ginkel, Kam Y. Au, Ramón Alemany, J. J. M. Meulenberg, Victor W. van Beusechem,

... lines derived from different tumor types demonstrated that ORCA-010 is more potent than Ad5-Δ24RGD or ONYX-015. As ORCA-010 will initially be developed for the treatment ... experiments were performed using primary human prostate cells. ORCA-010 killed cancer cells more effectively than these ... In both primary prostate fibroblasts and epithelial cells, ORCA-010 was as safe as Ad5-Δ24RGD. Evaluation of ORCA-010 in in vivo xenograft tumor models in nude mice showed that ORCA-010 significantly inhibited growth of prostate, lung, and ...

Tópico(s): RNA Interference and Gene Delivery

2014 - Mary Ann Liebert, Inc. | Human Gene Therapy

Jornais Acesso aberto

Otto Von Friesen, Carl Cederström, Otto Torell,

... Kongl. Vetenskaps- Akademiens Förhandlingar. Essay: Anteckningar Angående En Orca, Som Anträffats Vid Bohuslänska Kusten I December 1871 ...

1872 - Gale Group | NCCO-STM 1of2

Artigo Acesso aberto Revisado por pares

Yating Wang, Abid Khan, Anna B. Marks, Owen K. Smith, Sumanprava Giri, Yo-Chuen Lin, Rachel L. Creager, David M. MacAlpine, Kannanganattu V. Prasanth, Mirit I. Aladjem, Supriya G. Prasanth,

... of the cell cycle. The ORC-associated protein (ORCA/LRWD1) stabilizes ORC on chromatin. Here, we evaluated the genome-wide distribution of ORCA using ChIP-seq during specific time points of G1. ORCA binding sites on the G1 chromatin are dynamic and temporally regulated. ORCA association to specific genomic sites decreases as the ... progressed towards S-phase. The majority of the ORCA-bound sites represent replication origins that also associate ... chromatin marks H3K9me3 and methylated-CpGs, consistent with ORCA-bound origins initiating DNA replication late in S- ...

Tópico(s): Genomics and Chromatin Dynamics

2016 - Oxford University Press | Nucleic Acids Research

Jornais Acesso aberto

A. E. Nordenskiöld, A. W. Malm, A. Sinuosæ,

... Sp, Bullæ Tympani, Hæmapophyses, Scapulæ, Humerus, Radius & Ulna, Orca Eschrichtii Forma Beringensis Malm, Vertebræ Colli, Lamina Marginalis ...

1883 - Gale Group | NCCO SciTechMed 2 of 2

Artigo Acesso aberto Revisado por pares

Henri E. Bal, R.A.F. Bhoedjang, Rutger F. H. Hofman, Ceriel J. H. Jacobs, Koen Langendoen, Tim Rühl, M. Frans Kaashoek,

Orca is a portable, object-based distributed shared memory (DSM) system. This article studies and evaluates the design choices made in the Orca system and compares Orca with other DSMs. The article gives a quantitative analysis of Orca's coherence protocol (based on write-updates with ... the trade-offs made in the design of Orca and show that essentially the right design decisions ... update protocol with function shipping is effective for Orca, especially since it is used in combination with ... group communication on application performance is low. The Orca system is able to make near-optimal decisions ...

Tópico(s): Parallel Computing and Optimization Techniques

1998 - Association for Computing Machinery | ACM Transactions on Computer Systems

Artigo Acesso aberto Revisado por pares

Shaun D. Jackman, Tatyana Mozgacheva, Susie Chen, Brendan O’Huiginn, Lance R. Bailey, İnanç Birol, Steven J.M. Jones,

The ORCA bioinformatics environment is a Docker image that contains hundreds of bioinformatics tools and their dependencies. The ORCA image and accompanying server infrastructure provide a comprehensive bioinformatics environment for education and research. The ORCA environment on a server is implemented using Docker ... may not yet have familiarity with managing containers. ORCA has been used successfully to provide a private ... to-go bioinformatics suite for a hackathon. Using ORCA eliminates time that would be spent debugging software ...

Tópico(s): Scientific Computing and Data Management

2019 - Oxford University Press | Bioinformatics

Artigo Acesso aberto Revisado por pares

Frank Neese, Frank Wennmohs, Ute Becker, Christoph Riplinger,

... contribution to the special software-centered issue, the ORCA program package is described. We start with a ... go on to discuss its current feature set. ORCA has grown into a rather comprehensive general-purpose ... neighboring disciplines such as materials sciences and biochemistry. ORCA features density functional theory, a range of wavefunction ... featured as well as a complete intrinsic to ORCA quantum mechanics/molecular mechanics engine. A specialty of ORCA always has been a focus on transition metals ...

Tópico(s): Advanced NMR Techniques and Applications

2020 - American Institute of Physics | The Journal of Chemical Physics

Artigo Revisado por pares

John Totterdell, Rebecca Wellard, Isabella Reeves, Brodie Elsdon, Pia Markovic, Machi Yoshida, Ashleigh Fairchild, Gemma C. Sharp, Robert L. Pitman,

... The first three records of killer whales (Orcinus orca) killing and eating blue whales (Balaenoptera musculus) John ... WA, Cetacean Research Centre, Esperance, Western Australia Project ORCA, Orca Research and Conservation Australia, Perth, Western Australia Contribution: ... WA, Cetacean Research Centre, Esperance, Western Australia Project ORCA, Orca Research and Conservation Australia, Perth, Western Australia Centre ... Fairchild orcid.org/0000-0002-0247-714X Project ORCA, Orca Research and Conservation Australia, Perth, Western Australia ...

Tópico(s): Coral and Marine Ecosystems Studies

2022 - Wiley | Marine Mammal Science

Artigo Acesso aberto Revisado por pares

Caspian Oliai, Rasmus T. Hoeg, Anna Pavlova, Arpita Gandhi, Lori Muffly, Rohtesh S. Mehta, Samer A. Srour, Edmund K. Waller, Robert Lowsky, Sagar S. Patel, Bhagirathbhai Dholaria, Carlos Bachier, Jeremy Pantin, Amandeep Salhotra, Joseph P. McGuirk, Nathaniel B. Fernhoff, James Scott McClellan, Mehrdad Abedi, Robert S. Negrin, Everett Meyer,

... long been a key goal in the field. Orca-T is a high-precision, immunotherapy consisting of ... regulatory T cells to control alloreactive immune responses. Orca-T has demonstrated a favorable safety profile and ... of 15 July 2022, 180 patients have received Orca-T. Of those patients, 127 have ≥180 days ... or high risk MDS (n=15). Patients received Orca-T as part of a single-center Phase ... n=98; TBI-based, n=29) prior to Orca-T, followed by single-agent GVHD prophylaxis with ... DRI score and MRD status is ongoing. RESULTS Orca-T was successfully manufactured in a single, centralized ...

Tópico(s): CAR-T cell therapy research

2022 - Elsevier BV | Blood

Artigo Revisado por pares

William P. Cochlan, Deborah A. Bronk, Kenneth H. Coale,

... layer at two stations: a continental shelf station—Orca, and a high NO3−, low chlorophyll (HNLC) station ... sampled repeatedly during an 8-day period at Orca, and a 13-day period at Blue for ... chlorophyll a (chl a), was relatively high at Orca (chl a=2.31 μg l−1), whereas ... biomass. Chl a increased 2–3-fold at Orca and 4–5-fold at Blue; these increases ... biomass accumulation and nitrate drawdown were observed at Orca. Rates of biomass (particulate nitrogen) specific NO3−-uptake ... site, and only a 30–40% increase at Orca with the highest Fe enrichments. These results clearly ...

Tópico(s): Mercury impact and mitigation studies

2002 - Elsevier BV | Deep Sea Research Part II Topical Studies in Oceanography

Artigo Acesso aberto Revisado por pares

Ioanna Milenova, Marta López González, Dafne C.A. Quixabeira, João M. Santos, Víctor Cervera-Carrascón, Wen‐Liang Dong, Akseli Hemminki, Victor W. van Beusechem, Rieneke van de Ven, Tanja D. de Gruijl,

... myeloid regulatory cells in the tumor microenvironment (TME). ORCA-010 is a novel oncolytic adenovirus that selectively ... and lyses, cancer cells. We previously showed that ORCA-010 can activate melanoma-exposed conventional dendritic cells (cDCs). To study the effect of ORCA-010 on melanoma-conditioned macrophage development, we used ... Oncolysis of these melanoma cell lines, effected by ORCA-010, activated the resulting macrophages and converted them ... T cell response. To assess the effect of ORCA-010 on myeloid subset distribution and activation in ...

Tópico(s): Immunotherapy and Immune Responses

2021 - Mary Ann Liebert, Inc. | Human Gene Therapy

Artigo Acesso aberto Revisado por pares

Jennifer Kononowech, Hildi Hagedorn, Carmen Hall, Christian D. Helfrich, Anne Lambert‐Kerzner, Susan C. Miller, Anne Sales, Laura J. Damschroder,

... quantitative measures. The Organizational Resource and Context Assessment (ORCA) is a quantitative measurement instrument that was developed ... The aim of this work was to map ORCA survey items to CFIR constructs to enable direct ... findings across studies using the CFIR and/or ORCA. Methods Two distinct, independent research teams, each used ... and consensus to map individual items from the ORCA to the five domains and 39 constructs of CFIR. Results ORCA items were mapped primarily to three of five ... their mappings aligned for 62.2% of the ORCA items. Conclusions Mapping results reveal that the ORCA ...

Tópico(s): Community Health and Development

2021 - BioMed Central | Implementation Science Communications

Artigo Acesso aberto

Gary R. Winkler,

The Orca Group is a thick, complexly deformed, sparsely fossiliferous sequence of flysch-like sedimentary and tholeiitic volcanic rocks ... Sound region and the adjacent Chugach Mountains. The Orca Group also probably underlies a large part of ... called the Ghost Rocks and Sitkalidak Formations. The Orca Group was pervasively faulted, tightly folded, and metamorphosed ... In eastern Prince William Sound, 95% of the Orca sedimentary rocks are interbedded feldspathic and lithofeldspathic sandstone, ... the sedimentary rocks, and constitute 15-20% of Orca outcrops in eastern Prince William Sound. The basalt ...

Tópico(s): Methane Hydrates and Related Phenomena

1976 - United States Department of the Interior | Antarctica A Keystone in a Changing World

Artigo Acesso aberto Revisado por pares

Hildi Hagedorn, Paul W Heideman,

The Organizational Readiness to Change Assessment (ORCA) is a measure of organizational readiness for implementing practice change in healthcare settings that is organized based on the core elements and ... for the reliability and factor structure of the ORCA has been reported. However, no published study has examined the utility of the ORCA in a clinical setting. The purpose of the ... study was to examine the relationship between baseline ORCA scores and implementation of hepatitis prevention services in ...

Tópico(s): Evaluation and Performance Assessment

2010 - BioMed Central | Implementation Science

Artigo Acesso aberto Revisado por pares

Sumanprava Giri, Vasudha Aggarwal, Julien Pontis, Zhen Shen, Arindam Chakraborty, Abid Khan, Craig A. Mizzen, Kannanganattu V. Prasanth, Slimane Ait‐Si‐Ali, Taekjip Ha, Supriya G. Prasanth,

... pre-replication complex protein, origin recognition complex-associated (ORCA/LRWD1), preferentially localizes to heterochromatic regions in post- ... cells. Its role in heterochromatin organization remained elusive. ORCA recognizes methylated H3K9 marks and interacts with repressive ... manner. Single-molecule pull-down assays demonstrate that ORCA-ORC (Origin Recognition Complex) and multiple H3K9 KMTs exist in a single complex and that ORCA stabilizes H3K9 KMT complex. Cells lacking ORCA show alterations in chromatin architecture, with significantly reduced ...

Tópico(s): DNA Repair Mechanisms

2015 - eLife Sciences Publications Ltd | eLife

Artigo Revisado por pares

Annemarie Schaeffer Senders, Klaus E. Andersen, Carsten Bindslev‐Jensen, Charlotte G. Mørtz,

... Odense C, Denmark Odense Research Centre for Anaphylaxis (ORCA), Odense University Hospital, 5000 Odense C, DenmarkSearch for ... Odense C, Denmark Odense Research Centre for Anaphylaxis (ORCA), Odense University Hospital, 5000 Odense C, DenmarkSearch for ... Odense C, Denmark Odense Research Centre for Anaphylaxis (ORCA), Odense University Hospital, 5000 Odense C, DenmarkCorrespondence: Charlotte ... and Allergy Centre, Odense Research Centre for Anaphylaxis (ORCA), Odense University Hospital, University of Southern Denmark, Sdr. ...

Tópico(s): Drug-Induced Adverse Reactions

2016 - Wiley | Contact Dermatitis

Artigo Revisado por pares

Seán O'Sullivan, Keith D. Mullin,

... Issue 1 p. 141-147 KILLER WHALES (ORCINUS ORCA) IN THE NORTHERN GULF OF MEXICO Seán O' ... M. 1982. An assessment of killer whale (Orcinus orca) stocks off Vancouver Island, British Columbia. Report of ... organization and genealogy of resident killer whales (Orcinus orca) in the coastal waters of British Columbia and ... Siebenaler. 1956. Notes on a killer whale, Orcinus orca, from the northeastern Gulf of Mexico. Quarterly Journal ... whales: the natural history and genealogy of Orcinus orca in British Columbia and Washington state. University of ...

Tópico(s): Animal Vocal Communication and Behavior

1997 - Wiley | Marine Mammal Science

Artigo Revisado por pares

John Jett, Ingrid N. Visser, Jeffrey Ventre, J. A. Waltz, Carolina Loch,

... result of oral stereotypies is evident in captive orca, yet little research on the topic exists. This ... duration of captivity and other factors in captive orca.We evaluated mandibular and maxillary teeth from dental images of 29 captive orca owned by a US-based theme park. Each ... captured and captive-born orcas and between captive orca at four facilities. We also evaluated how dental ... evidence of having been drilled. Four of five orca with the highest age-adjusted tooth pathology indices ... a young age. Oral stereotypies exhibited by captive orca contributed to the observed dental damage. By making ...

Tópico(s): Animal Nutrition and Physiology

2017 - Elsevier BV | Archives of Oral Biology

Artigo Revisado por pares

James P. Kennett, K Elmstrom, N. Penrose,

Anoxic sediments in Orca Basin, northern Gulf of Mexico (water depth 2400 m) provide late Quaternary planktonic foraminiferal and paleoclimatic records of remarkably ... Black, organic-rich, strongly laminated, unbioturbated muds of Orca Basin contrast with grayish, organic-poor, bioturbated sediments ... their preservation does not match those from the Orca Basin. Planktonic foraminiferal assemblages have been counted in two piston cores from Orca Basin that are as old as 29 kyrs ... This meltwater effect is strongly recorded in the Orca Basin sequence. Faunal and stable-isotope changes have ...

Tópico(s): Isotope Analysis in Ecology

1985 - Elsevier BV | Palaeogeography Palaeoclimatology Palaeoecology

Artigo Acesso aberto Revisado por pares

Henri E. Bal, M. Frans Kaashoek, Andrew S. Tanenbaum,

Orca is a language for implementing parallel applications on loosely coupled distributed systems.Unlike most languages for ... user-defined abstract data types.The implementation of Orca takes care of the physical distribution of objects ... This paper gives a detailed description of the Orca language design and motivates the design choices.Orca is intended for applications programmers rather than systems ... The paper discusses three example parallel applications in Orca, one of which is described in detail.It ...

Tópico(s): Distributed and Parallel Computing Systems

1992 - IEEE Computer Society | IEEE Transactions on Software Engineering

Artigo Acesso aberto Revisado por pares

Robert R. Edelman, Pippa Storey, Eugene Dunkle, Wei Li, Andrés Carrillo, Anthony T. Vu, Timothy J. Carroll,

... MRA, which we call “off‐resonance contrast angiography” (ORCA). Unlike standard contrast‐enhanced (CE) MR angiography (MRA), ORCA contrast depends not on T 1 but on ... oxide contrast agent (CA). With the use of ORCA, complete background suppression was obtained without image subtraction. ... Gd dilutions proved to be highly conspicuous in ORCA projection images. This feature may make ORCA particularly attractive for passive catheter tracking during MR‐ ... and found to be in the expected range. ORCA was used to create angiograms of forearm veins ...

Tópico(s): MRI in cancer diagnosis

2007 - Wiley | Magnetic Resonance in Medicine

Artigo Revisado por pares

A. Schulte, Nigel Pitts,

... are changing, the European Organisation for Caries Research (ORCA) responded to an increasing demand to provide its ... task for future dentists. Thus, in 2006, the ORCA Board nominated several senior colleagues from different European ... Inspired by the feedback from the returned questionnaires, ORCA and the Association of Dental Education in Europe (ADEE) decided to cooperate so that the ORCA Cariology Curriculum Committee became a joint ORCA/ADEE project. One milestone of this fruitful cooperation ... development of a European Curriculum for Cariology. This ORCA/ADEE workshop was held between 27th and 30th ...

Tópico(s): Dental Research and COVID-19

2011 - Wiley | European Journal Of Dental Education

Artigo Revisado por pares

G. Lang Farmer, Robert A. Ayuso, George Plafker,

... the Late Cretaceous and early Tertiary Valdez and Orca Groups in southern Alaska to determine the flysch provenance. Argillites and greywackes from the Orca Group, as well as compositionally similar but higher ... 204Pb= 38.677–39.209), and in the Orca Group the samples generally become more radiogenic with ... tonalite clast and a rhyodacite clast in the Orca Group (εNd = −4.9and−0.9, respectively). However, trondjemitic clasts in the Orca Group have significantly lower εNd ( ∼ −10) and require ... Pb isotopic compositions of both the Valdez and Orca Groups overlap the values determined for intrusive igneous ...

Tópico(s): Geochemistry and Geologic Mapping

1993 - Elsevier BV | Earth and Planetary Science Letters