Raffaella Origa, Antonio Piga, Immacolata Tartaglione, Giuseppina Della Corte, Gian Luca Forni, Andreas Bruederle, Chiara Castiglioni, Jackie Han,
... 7 Vicenzo Caruso,8 Silvana Guzzardi,8 Raffaella Origa,9 Antonietta Zappu,10 Maria Rita Gamberini,11 ... Presidio Osp. A. Perrino- ASL BR, Brindisi. R. Origa reports honoraria from Novartis and ApoPharma, Inc. A. ... G. Della Corte have nothing to disclose. Raffaella Origa, Antonio Piga, Immacolata Tartaglione, Giuseppina Della Corte and ...
Tópico(s): Erythropoietin and Anemia Treatment
2018 - Wiley | American Journal of Hematology
Khaled M. Musallam, Susanna Barella, Raffaella Origa, Giovanni Battista Ferrero, Roberto Lisi, A Pasanisi, Filomena Longo, Barbara Gianesin, Gian Luca Forni,
... author on: This Site PubMed Google Scholar Raffaella Origa, Raffaella Origa Ospedale Microcitemico A.Cao-University of Cagliari, Cagliari, ... Site Citation Khaled M. Musallam, Susanna Barella, Raffaella Origa, Giovanni Battista Ferrero, Roberto Lisi, Annamaria Pasanisi, Filomena ...
Tópico(s): Neonatal Health and Biochemistry
2023 - Elsevier BV | Blood
Muhammad Naseer Bajwa, Muhammad Imran Malik, Shoaib Ahmed Siddiqui, Andreas Dengel, Faisal Shafait, Wolfgang Neumeier, Sheraz Ahmed,
... publicly available datasets for disc localization and on ORIGA dataset, which is the largest publicly available dataset ... the-art results previously obtained for classification on ORIGA. Once trained on carefully annotated data, Deep Learning ... algorithms. Our empirical evaluation of glaucoma classification on ORIGA reveals that reporting only AUC, for datasets with ...
Tópico(s): Digital Imaging for Blood Diseases
2019 - BioMed Central | BMC Medical Informatics and Decision Making
Faizan Abdullah, Rakhshanda Imtiaz, Hussain Ahmad Madni, Haroon Ahmed Khan, Tariq M. Khan, Mohammad A. U. Khan, Syed S. Naqvi,
... that are manually annotated by six ophthalmologists. H. ORIGA-LIGHTThe retinal fundus images present in the ORIGA-light dataset are collected by the Singapore Malay ... annotated these 650 images that exist in the ORIGA-light dataset. I. ACRIMAThis dataset consists of 705 ...
Tópico(s): Glaucoma and retinal disorders
2021 - Institute of Electrical and Electronics Engineers | IEEE Access
Abdelali Elmoufidi, Ayoub Skouta, Said Jai Andaloussi, Ouail Ouchetto,
... four other public datasets, which are RIM-ONE, ORIGA-light, Drishti-GS1, and sjchoi86-HRF. The overall ... 60% is obtained on ACRIMA, REFUGE, RIM-ONE, ORIGA-light, Drishti-GS1, and sjchoi86-HRF datasets, respectively, ... is obtained in the ACRIMA, REFUGE, RIM-ONE, ORIGA-light, Drishti-GS1, and sjchoi86-HRF datasets, respectively, ...
Tópico(s): Retinal Diseases and Treatments
2022 - World Scientific | International Journal of Image and Graphics
Alì Taher, Khaled M. Musallam, John C. Wood, Maria Domenica Cappellini,
... Curr Opin Hematol 2007; 14: 183– 190. 5 Origa R,Galanello R,Ganz T, et al. Liver ... thalassemia major. Haematologica 2006; 91: 809– 812. 10 Origa R,Barella S,Argiolas GM, et al. No ...
Tópico(s): Iron Metabolism and Disorders
2009 - Wiley | American Journal of Hematology
Huazhu Fu, Jun Cheng, Yanwu Xu, Damon Wing Kee Wong, Jiang Liu, Xiaochun Cao,
... the-art OD and OC segmentation result on ORIGA data set. Simultaneously, the proposed method also obtains ... screening performances with calculated CDR value on both ORIGA and SCES datasets.
Tópico(s): Digital Imaging for Blood Diseases
2018 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Medical Imaging
Qing Liu, Xiaopeng Hong, Shuo Li, Zailiang Chen, Guoying Zhao, Beiji Zou,
... segmentation method on two public datasets, i.e., ORIGA and DRISHTI. Based on the segmentation masks, we ... of the glaucoma is validated on the dataset ORIGA.
Tópico(s): Intraocular Surgery and Lenses
2019 - Elsevier BV | Neurocomputing
Yan Huang, Chenhui Ding, Puping Liang, Duanduan Li, Yu Tang, Meng Wei, Hongwei Sun, Hongyu Lu, Yu Chen, Xueying Chen, Qunshan Huang, Jian‐Pei Fang, Canquan Zhou, Shihua Yang, Junjiu Huang,
... affects approximately 1.5% of the global population (Origa, 2017).In southern China, the carrier rate of ... rare dominant mutations, most HBB mutations are recessive (Origa, 2017).Depending on the mutation type, the β- ...
Tópico(s): Drug Transport and Resistance Mechanisms
2019 - Springer Science+Business Media | Protein & Cell
Poonguzhali Elangovan, Malaya Kumar Nath,
... The proposed network is tested on DRISHTI–GS1, ORIGA, RIM–ONE2 (release 2), ACRIMA, and large–scale ... 64% are obtained on DRISHTI–GS1, RIM–ONE2, ORIGA, LAG, and ACRIMA databases, respectively. The proposed method ...
Tópico(s): Digital Imaging for Blood Diseases
2020 - Wiley | International Journal of Imaging Systems and Technology
Santosh Kumar Sharma, Debendra Muduli, Rojalina Priyadarshini, Rakesh Ranjan Kumar, Abhinav Kumar, Jitesh Pradhan,
... model deployed on two standard datasets, G1020 and ORIGA. The experimental results show that the proposed computer- ... 80% and 98.46% on the G1020 and ORIGA datasets, respectively. The customized CNN model outperforms as ...
Tópico(s): Glaucoma and retinal disorders
2023 - Elsevier BV | Engineering Applications of Artificial Intelligence
Rashmi Panda, Niladri B. Puhan, Bappaditya Mandal, Ganapati Panda,
... on publicly available DRISHTI-GS, RIM-ONE and ORIGA-light datasets. The experimental results for optic disc ... 0.8106 in DRISHTI-GS, RIM-ONE and ORIGA-light, respectively. Finally, the glaucoma risk index is ...
Tópico(s): Digital Imaging for Blood Diseases
2021 - Springer Nature | SN Computer Science
Ömer Deperlioğlu, Utku Köse, Deepak Gupta, Ashish Khanna, Fabio Giampaolo, Giancarlo Fortino,
... hybrid solution was tested with the Drishti-GS, ORIGA−Light and HRF retinal image datasets through a ... the highest mean values were found with the ORIGA−Light dataset (with accuracy: 93.5%, sensitivity/ recall: ...
Tópico(s): Acute Ischemic Stroke Management
2021 - Elsevier BV | Future Generation Computer Systems
Jahanzaib Latif, Shanshan Tu, Chuangbai Xiao, Sadaqat Ur Rehman, Azhar Imran, Yousaf Latif,
... maps are evaluated on five public retinal datasets (ORIGA, HRF, DRIONS-DB, DR-HAGIS, and RIM-ONE) ... results demonstrate that the proposed ODGNet evaluated on ORIGA for glaucoma diagnosis is the most predictive model ...
Tópico(s): Digital Imaging for Blood Diseases
2022 - Springer Nature | SN Applied Sciences
Poonguzhali Elangovan, Malaya Kumar Nath,
... databases are modified (such as: DRISHTI‐GS1‐R, ORIGA‐R, RIM‐ONE2‐R, LAG‐R, and ACRIMA‐ ... 5%, and 99.6% in DRISHTI‐GS1‐R, ORIGA‐R, RIM‐ONE2‐R, ACRIMA‐R, and LAG‐ ...
Tópico(s): Digital Imaging for Blood Diseases
2022 - Wiley | International Journal of Imaging Systems and Technology
Maria Domenica Cappellini, Vip Viprakasit, Alì Taher, Pencho Georgiev, Kevin H.M. Kuo, Thomas D. Coates, Ersi Voskaridou, Hong Keng Liew, Idit Pazgal-Kobrowski, Gian Luca Forni, Silverio Perrotta, Abderrahim Khélif, Ashutosh Lal, Antonis Kattamis, Efthymia Vlachaki, Raffaella Origa, Yeşim Aydınok, Mohamed Béjaoui, P. Joy Ho, Lee Ping Chew, Ping Chong Bee, Soo Min Lim, Meng‐Yao Lu, Adisak Tantiworawit, Penka Ganeva, Liana Gercheva, Farrukh Shah, Ellis J. Neufeld, Abderrahmane Laadem, Jeevan K. Shetty, Jun Zou, Dimana Miteva, Tatiana Zinger, Peter G. Linde, Matthew L. Sherman, Olivier Hermine, John B. Porter, Antonio Piga,
... Consultancy, Honoraria; Novartis: Consultancy, Honoraria. Vlachaki:Novartis: Honoraria. Origa:Cerus Corporation: Research Funding; Bluebird Bio: Consultancy; Novartis: ...
Tópico(s): Erythrocyte Function and Pathophysiology
2018 - Elsevier BV | Blood
M. Cau, Rita Congiu, Raffaella Origa, R. Galanello, Marco Melis, A Nucaro,
... Cagliari, ItalySearch for more papers by this authorR. Origa, R. Origa Dipartimento di Scienze Biomediche e Biotecnologie, Università di ... Cagliari, ItalySearch for more papers by this authorR. Origa, R. Origa Dipartimento di Scienze Biomediche e Biotecnologie, Università di ...
Tópico(s): Congenital Ear and Nasal Anomalies
2005 - Wiley | American Journal of Medical Genetics Part A
K. Kodaira, Kazumi Nakano, Akira Taketo,
... 5. From the oriAA, a revertant-like phage oriGA occurred spontaneously with a high-frequency of about ...
Tópico(s): RNA and protein synthesis mechanisms
1989 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
Raffaella Origa, Antonio Piga, Giovanni Quarta, Gian Luca Forni, Filomena Longo, Angela Melpignano, R. Galanello,
Background Recent advances in the management of thalassemia have significantly improved life expectancy and quality of life of patients with this hemoglobinopathy, with a consequent increase in their reproductive potential and desire to have children.Design and Methods We describe the methods of conception and delivery, as well as the course and outcome of pregnancy including transfusions, iron overload and chelation in 46 women with thalassemia major (58 pregnancies) and in 11 women with thalassemia ...
Tópico(s): Prenatal Screening and Diagnostics
2009 - Ferrata Storti Foundation | Haematologica
Ersi Voskaridou, Eleni Plata, Maroussa Douskou, Manousos Papadakis, Eleni‐Evangelia Delaki, Dimitrios Christoulas, Evangelos Terpos,
... iron loading has not been documented in TI (Origa et al, 2008). In agreement with these observations, ...
Tópico(s): Iron Metabolism and Disorders
2009 - Wiley | British Journal of Haematology
Antonio Macciò, Clelia Madeddu, Paola Chessa, Giovanni Mantovani, Renzo Galanello,
... health of the mother and the developing foetus (Origa et al, 2007). Pre-eclampsia, congestive heart failure, ...
Tópico(s): Erythropoietin and Anemia Treatment
2009 - Wiley | British Journal of Haematology
Raffaella Origa, S. Satta, Gildo Matta, R. Galanello,
The heart is the target lethal organ for iron accumulation in thalassaemia major (TM) and heart failure secondary to iron overload is still the main cause of death in transfusion-dependent patients. Currently, magnetic resonance imaging (MRI) is the only non-invasive method with the potential to assess myocardial iron. The MRI T2* parameter has proven to be a fast, simple, robust parameter and, although it has not been calibrated with chemical measurements of endomyocardial iron in humans, growing ...
Tópico(s): Trace Elements in Health
2008 - Wiley | British Journal of Haematology
Raffaella Origa, Susanna Barella, G. Argiolas, Patrizio Bina, Annalisa Agus, R. Galanello,
No evidence of cardiac iron in 20 never-or minimally-transfused
Tópico(s): Iron Metabolism and Disorders
2008 - Ferrata Storti Foundation | Haematologica
Renzo Galanello, Raffaella Origa,
The increasing use of blood transfusions, combined with extended patient survival, has led to an increase in the number of patients at risk of developing transfusional iron overload. Clinical data have shown that the once-daily oral iron chelator deferasirox is effective in adults and children with various transfusion-dependent anemias, including β-thalassemia and the myelodysplastic syndromes. Deferasirox has a defined, clinically manageable safety profile. The most common treatment-related adverse ...
Tópico(s): Erythropoietin and Anemia Treatment
2008 - Taylor & Francis | Expert Review of Clinical Pharmacology
Maud Kamatenesi‐Mugisha, Hannington Oryem‐Origa, Olwa Odyek, D.W. Makawiti,
Abstract In Uganda, bacterial and fungal infections are prevalent especially, the sexually transmitted diseases including HIV/AIDS. Because of low socio‐economic empowerment, traditional beliefs and cultural barriers, the suffering people resort to use of herbal remedies in search of cure especially for rural women who rarely discuss/disclose diseases affecting secretive body parts. The study documented 67 medicinal plants distributed among 27 families and 51 genera used to treat fungal and bacterial ...
Tópico(s): Essential Oils and Antimicrobial Activity
2008 - Wiley | African Journal of Ecology
John C. Wood, Raffaella Origa, Annalisa Agus, Gildo Matta, Thomas D. Coates, R. Galanello,
We reviewed cardiac T2* assessments from 77 thalassemia major patients between the ages of 2.5 and 18 years to study optimal timing of cardiac iron screening by magnetic resonance imaging. No patient under 9.5 years of age showed detectable cardiac iron in contrast to 36% of patients between the ages of 15-18 years old, corresponding to an odds-ratio of 1.28 (28%) per year. All patients with cardiac iron had received at least 35 grams of transfusional iron. Liver iron and ferritin failed to predict ...
Tópico(s): Autopsy Techniques and Outcomes
2008 - Ferrata Storti Foundation | Haematologica
Petter Portin, Mirja Rantanen,
... Der. 3: 1113– 1129. Knust, E. and Campos-Origa, J. A. 1989. TV molecular genei-ics of ...
Tópico(s): Plant Reproductive Biology
2008 - BioMed Central | Hereditas
Raffaella Origa, Renzo Galanello, Lucia Perseu, Dario Tavazzi, Maria Domenica Cappellini, Laura Terenzani, Gian Luca Forni, Giovanni Quarta, Tatiana Boetti, Antonio Piga,
Aim of this study was to evaluate prevalence and characteristics of cholelithiasis in a large population of patients with thalassemia major (TM).Data from 858 consecutive patients with transfusion-dependent thalassemia at five major Italian centers were analyzed. In these centers, a complete abdomen ultrasonography is performed yearly after the beginning of the transfusion regimen. The role of co-inheriting Gilbert's syndrome genotype was investigated studying the promoter region of the UGT1-A1 gene ...
Tópico(s): Gallbladder and Bile Duct Disorders
2008 - Wiley | European Journal Of Haematology
Pasquale Ena, D. Origa, Giovannino Massarelli,
Two men, aged in their 20s, presented with multiple, soft, rounded papules on the prepuce. The lesions were centrally umbilicated, resembling molluscum contagiosum, but clearly distinct from Tyson's glands. Surface microscopy showed well-defined, milky-white, bag-shaped structures, which under histological examination were found to be sebaceous glands with various features of hyperplasia. A lymphocytic T-cell infiltrate, closely associated with progressive degeneration and destruction of the sebocytes, ...
Tópico(s): Cancer and Skin Lesions
2008 - Oxford University Press | Clinical and Experimental Dermatology
Asher Winder, Rafi Lefkowitz, Hussam Ghoti, Merav Leiba, Tomas Ganz, Elizabeta Nemeth, Eliezer A. Rachmilewitz,
... presumably due to transfusions which decrease erythropoietic drive (Origa et al, 2007). The present study investigated whether ...
Tópico(s): Erythropoietin and Anemia Treatment
2008 - Wiley | British Journal of Haematology