Produção Nacional
Revisado por pares
José de Souza Andrade, Eduardo Alves Bambirra, Otacílio Jose Bicalho, Antônio Francisco de Souza,
... Infertility Jose de Souza Andrade, Eduardo Alves Bambirra, Otacílio Jose Bicalho, and Antonio Francisco de Souza Jose ... de Souza Andrade , Eduardo Alves BambirraEduardo Alves Bambirra , Otacílio Jose BicalhoOtacílio Jose Bicalho , and Antonio Francisco de ... Eduardo Alves Bambirra More articles by this author Otacílio Jose Bicalho More articles by this author Antonio ...
Tópico(s): Bladder and Urothelial Cancer Treatments
1985 - Lippincott Williams & Wilkins | The Journal of Urology
Produção Nacional
Revisado por pares
Carlos José Mendes, Cíntia Urbano Neves, Ricardo Berger,
... de questionários aos produtores rurais no município de Otacílio Costa (SC). A interpretação dos resultados indica que ... of land owners from the rural city of Otacílio Costa, SC. The Legal Forest Reserve is a ... based on questionnaires applied to the landowners in Otacílio Costa city, Santa Catarina State. The results points ...
Tópico(s): Agricultural and Food Sciences
2012 - UNIVERSIDADE FEDERAL DO PARANÁ | FLORESTA
Produção Nacional
Revisado por pares
Pau Bosch‐Nicolau, Marisa Fernández, Elena Sulleiro, Juan Carlos Villar, José A. Pérez‐Molina, Rodrigo Corrêa‐Oliveira, Sergio Sosa‐Estáni, Adrián Sánchez‐Montalvá, María del Carmen Bangher, Otacílio C. Moreira, Fernando Salvador, Ariela Mota Ferreira, Silvana Maria Elói-Santos, Núria Serre‐Delcor, Juan Carlos Ramı́rez, Aroa Silgado, Inês Oliveira, Oihane Martín, María Luisa Aznar, Antônio Luiz Pinho Ribeiro, Paulo Emílio Clementino Almeida, Sandra Chamorro-Tojeiro, Juan Espinosa‐Pereiro, Alfredo Maurício Batista de Paula, Eliana Vàquiro-Herrera, Carmen Tur, Israel Molina,
Background Treatment with benznidazole for chronic Chagas disease is associated with low cure rates and substantial toxicity. We aimed to compare the parasitological efficacy and safety of 3 different benznidazole regimens in adult patients with chronic Chagas disease. Methods The MULTIBENZ trial was an international, randomised, double-blind, phase 2b trial performed in Argentina, Brazil, Colombia, and Spain. We included participants aged 18 years and older diagnosed with Chagas disease with two ...
Tópico(s): Synthesis and Biological Evaluation
2024 - Elsevier BV | The Lancet Infectious Diseases
Produção Nacional
Revisado por pares
Abraão G. C. Menezes, Mateus M. Araujo, Otacílio M. Almeida, Fábio Rocha Barbosa, Arthur P. S. Braga,
This article describes the use of a decision tree (DT) approach based on computational intelligence (CI) for the analysis and diagnosis of incipient faults in power transformers. The method relies on measuring the combustible gas concentration in parts per million (ppm) from samples of the insulating oil. Currently, the Duval triangle method is one of the most traditional techniques used for the dissolved gas analysis (DGA), but it has limited accuracy. To overcome such conventional performance problems, ...
Tópico(s): Water Quality Monitoring and Analysis
2022 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Dielectrics and Electrical Insulation
Produção Nacional
Revisado por pares
Ludmila Ferreira de Almeida Fiuza, D. G. J. Batista, Roberson Donola Girão, Fabian Hulpia, Paula Finamore-Araújo, Mustafa M. Aldfer, Ehab Kotb Elmahallawy, Harry P. de Koning, Otacílio C. Moreira, Serge Van Calenbergh, Maria de Nazaré Correia Soeiro,
Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is a serious public health problem. Current treatment is restricted to two drugs, benznidazole and nifurtimox, displaying serious efficacy and safety drawbacks. Nucleoside analogues represent a promising alternative as protozoans do not biosynthesize purines and rely on purine salvage from the hosts. Protozoan transporters often present different substrate specificities from mammalian transporters, justifying the exploration of nucleoside analogues ...
Tópico(s): Research on Leishmaniasis Studies
2022 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Vanessa Cristine de Souza Carneiro, Soniza Vieira Alves‐Leon, Dmitry José de Santana Sarmento, Wagner Luís da Costa Nunes Pimentel Coelho, Otacílio C. Moreira, Andreza Lemos Salvio, Carlos Henrique Ferreira Ramos, Carlos Henrique Ferreira Ramos Filho, Carla Augusta Barreto Marques, João Paulo da Costa Gonçalves, Luciane Almeida Amado Leon, Vanessa Salete de Paula,
Abstract Background Certain clinical manifestations of coronavirus disease (COVID-19) mimic those associated with human herpesvirus (HHV) infection. In this study, we estimated the prevalence of herpesvirus in patients with COVID-19 and determined if coinfection is associated with poorer outcomes and neurological symptoms. Methods We analyzed samples of 53 patients diagnosed with COVID-19. The samples were evaluated for the presence of alphaherpesviruses, betaherpesviruses, and gammaherpesviruses, ...
Tópico(s): COVID-19 Clinical Research Studies
2022 - BioMed Central | Virology Journal
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Philipp Schwabl, Mariana Côrtes Boité, Giovanni Bussotti, Arne Jacobs, Björn Andersson, Otacílio C. Moreira, Anita Leocádio Freitas-Mesquita, José Roberto Meyer‐Fernandes, Erich Loza Telleria, Yara Maria Traub-Csekö, Slavica Vaselek, Tereza Leštinová, Petr Volf, Fernanda N. Morgado, Renato Porrozzi, Martin Llewellyn, Gérald F. Späth, Elisa Cupolillo,
Leishmania infantum causes visceral leishmaniasis, a deadly vector-borne disease introduced to the Americas during the colonial era. This non-native trypanosomatid parasite has since established widespread transmission cycles using alternative vectors, and human infection has become a significant concern to public health, especially in Brazil. A multi-kilobase deletion was recently detected in Brazilian L. infantum genomes and is suggested to reduce susceptibility to the anti-leishmanial drug miltefosine. ...
Tópico(s): Parasites and Host Interactions
2021 - Nature Portfolio | Communications Biology
Produção Nacional
Revisado por pares
Marcelo Teixeira de Holanda, Mauro Felippe Felix Mediano, Alejandro Marcel Hasslocher‐Moreno, Beatriz Matheus de Souza Gonzaga, Anna Cristina Calçada Carvalho, Roberto Rodrigues Ferreira, Luciana Ribeiro Garzoni, Fernanda Sant’Ana Pereira-Silva, Luis O. Pimentel, Marcelo Oliveira Mendes, Marcos José de Azevedo, Constança Britto, Otacílio C. Moreira, Alice Gomes Fernandes, Carolina Santos, Jéssica Constermani, Vitor Barreto Paravidino, Erica Rodrigues Maciel, Fernanda Martins Carneiro, Sérgio Salles Xavier, Gilberto M. Sperandio da Silva, Priscila F. Santos, Henrique Horta Veloso, Pedro Emmanuel Alvarenga Americano do Brasil, Andréa Silvestre de Sousa, Maria G. Bonecini-de-Almeida, Paula Simplício da Silva, Luiz Henrique Conde Sangenis, Roberto Magalhães Saraiva, Tânia Cremonini de Araújo-Jorge,
Chagas disease (caused by Trypanosoma cruzi infection) evolves to chronic chagasic cardiomyopathy (CCC) affecting 1.8 million people worldwide. This is the first randomized, placebo-controlled, double-blinded, clinical trial designed to estimate efficacy and safety of selenium (Se) treatment in CCC.66 patients with CCC stages B1 (left ventricular ejection fraction [LVEF] > 45% and no heart failure; n = 54) or B2 (LVEF < 45% and no heart failure; n = 12) were randomly assigned to receive 100 mcg/day sodium selenite ( ...
Tópico(s): Cardiovascular Issues in Pregnancy
2021 - Elsevier BV | EClinicalMedicine
Produção Nacional
Revisado por pares
Gláucia Vilar-Pereira, Leda Castaño Barrios, Andréa Silva, Angélica Martins Batista, Isabela Resende Pereira, Otacílio C. Moreira, Constança Britto, Hílton Antônio Mata dos Santos, Joseli Lannes-Vieira,
Memory impairment has been associated with chronic Chagas disease (CD), a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi . In degenerative diseases, memory loss has been associated with increased oxidative stress, revealed as enhanced lipid peroxidation, in the cerebral cortex. Benznidazole (Bz), a trypanocidal drug efficient to reduce blood parasite load in the acute and chronic phases of infection, showed controversial effects on heart disease progression, the main clinical ...
Tópico(s): Parasites and Host Interactions
2021 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Beatriz Iandra da Silva Ferreira, Natália Lins Silva-Gomes, Wagner Luís da Costa Nunes Pimentel Coelho, Vanessa Duarte da Costa, Vanessa Cristine de Souza Carneiro, Rafael Lopes Kader, Marisa Pimentel Amaro, Lívia Melo Villar, Fábio Miyajima, Soniza Vieira Alves‐Leon, Vanessa Salete de Paula, Luciane Almeida Amado Leon, Otacílio C. Moreira,
The emergence of the COVID-19 pandemic resulted in an unprecedented need for RT-qPCR-based molecular diagnostic testing, placing a strain on the supply chain and the availability of commercially available PCR testing kits and reagents. The effect of limited molecular diagnostics-related supplies has been felt across the globe, disproportionally impacting molecular diagnostic testing in developing countries where acquisition of supplies is limited due to availability. The increasing global demand ...
Tópico(s): Viral gastroenteritis research and epidemiology
2021 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Jaisson Agne Estrázulas, Jansen Atier Estrázulas, Kelly de Jesus, Karla de Jesus, Rubens Alexandre da Silva, João Otacílio Libardoni dos Santos,
To systematically review the literature analyzing the reliability and characteristics of the protocols of isokinetic and isometric evaluation of the trunk flexor and extensor muscles with isokinetic dynamometer. This is a systematic review using PubMed, CENTRAL, LILACS, PEDro and SCOPUS databases, searching the oldest records up to December 2019. The risk of bias, the methodological quality and the level of evidence were evaluated using the COSMIN checklist. Fourteen articles have met the criteria ...
Tópico(s): Motor Control and Adaptation
2020 - Elsevier BV | Physical Therapy in Sport
Produção Nacional
Revisado por pares
Marco Antonio Prates Nielebock, Otacílio C. Moreira, Samanta Cristina das Chagas Xavier, Luciana de Freitas Campos Miranda, Ana Carolina Bastos de Lima, Thayanne Oliveira de Jesus Sales Pereira, Alejandro Marcel Hasslocher‐Moreno, Constança Britto, Luiz Henrique Conde Sangenis, Roberto Magalhães Saraiva,
Background The specific roles of parasite characteristics and immunological factors of the host in Chagas disease progression and prognosis are still under debate. Trypanosoma cruzi genotype may be an important determinant of the clinical chronic Chagas disease form and prognosis. This study aimed to identify the potential association between T . cruzi genotypes and the clinical presentations of chronic Chagas disease. Methodology/principal findings This is a retrospective study using T . cruzi isolated ...
Tópico(s): Research on Leishmaniasis Studies
2020 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Alessandra Juliê Schuster, Raissa Micaella Marcello‐Machado, Amália Machado Bielemann, Anna Paula da Rosa Possebon, Otacílio Luiz Chagas Júnior, Fernanda Faot,
Abstract Background The use of immediate loading (IML) is still poorly explored in elderly patients and implant‐retained mandibular overdenture (IMO) wearers. For this reason, more comparisons to conventional loading (CL) are required. Purpose To evaluate the clinical, biological, functional, and oral health‐related quality of life (OHRQOL) influence of CL and IML loading on elders wearing IMO retained by the Facility‐Equator system up to 1 year after implant installation. Material and Methods Twenty ...
Tópico(s): Dental materials and restorations
2020 - Wiley | Clinical Implant Dentistry and Related Research
Produção Nacional
Revisado por pares
Karine Batista dos Santos, Vítor Otacílio de Almeida, Jéssica Weiler, Ivo Schneider,
This work evaluates the benefits of a complementary treatment step of acid mine drainage (AMD) using the algae Scenedesmus sp. in terms of algae biomass production, residual metal removal, and the toxicity of the discharged water. Conventional treatment by neutralization/precipitation of an AMD from a coal mine in Brazil was conducted with Ca(OH)2 at pH 8.7. Algal growth studies were performed in the treated AMD, with and without a nutrient supply. The raw effluent and treatments were compared in ...
Tópico(s): Geochemistry and Elemental Analysis
2020 - Multidisciplinary Digital Publishing Institute | Minerals
Produção Nacional
Revisado por pares
Talita Carneiro Brandão Pereira, Karine Batista dos Santos, William Lautert-Dutra, Lílian de Souza Teodoro, Vítor Otacílio de Almeida, Jéssica Weiler, Ivo Schneider, Maurı́cio Reis Bogo,
Acid mine drainage (AMD) represents a major problem in the mining industry worldwide due to the risk of water and soil pollution. Its active treatment involves the addition of alkaline reagents such as NaOH or Ca(OH)2 to increase the pH and precipitate the dissolved metals, although substantial amounts of dissolved ions might persists. Under a remediation approach, the aim of this work was to assess the chemical and physical characteristics of treated effluent and to evaluate its ecotoxicological ...
Tópico(s): Tailings Management and Properties
2020 - Elsevier BV | Chemosphere
Produção Nacional
Revisado por pares
Vítor Otacílio de Almeida, Ivo Schneider,
This work aimed at producing a ferric chloride coagulant from an iron ore tailing. The investigated variables were temperature, hydrochloric acid concentration, and heating time. The results indicated increasing solubilization of iron as a function of HCl concentration and temperature. Leaching carried out with a 10.8 mol L-1 of HCl at a temperature of 80° for 120 min resulted in a 94% recovery of iron present in the iron ore tailing. The leachate presented 11% Fe in its composition and a low concentration ...
Tópico(s): Mine drainage and remediation techniques
2020 - Elsevier BV | Minerals Engineering
Produção Nacional
Revisado por pares
Vinícius Capistrano, Paulo Nobre, Sandro F. Veiga, Renata G. Tedeschi, Josiane Silva, Marcus Jorge Bottino, Manoel Baptista da Silva, Otacílio Leandro Menezes Neto, Silvio Nilo Figueroa, José Paulo Bonatti, Paulo Yoshio Kubota, Júlio Pablo Reyes Fernández, Emanuel Giarolla, Jessica Vial, Carlos A. Nobre,
Abstract. The main features of climate change patterns, as simulated by the coupled ocean–atmosphere version 2.5 of the Brazilian Earth System Model (BESM), are compared with those of 25 other CMIP5 models, focusing on temperature, precipitation, atmospheric circulation, and radiative feedbacks. The climate sensitivity to quadrupling the atmospheric CO2 concentration was investigated via two methods: linear regression (Gregory et al., 2004) and radiative kernels (Soden and Held, 2006; Soden et al., ...
Tópico(s): Atmospheric chemistry and aerosols
2020 - Copernicus Publications | Geoscientific model development
Produção Nacional
Revisado por pares
Camila Patrício Braga Filgueira, Otacílio C. Moreira, Lilian Motta Cantanhêde, Heloísa Martins Teixeira de Farias, Renato Porrozzi, Constança Britto, Mariana Côrtes Boité, Elisa Cupolillo,
Leishmaniasis is a worldwide neglected disease, encompassing asymptomatic infections and different clinical forms, such as American Tegumentary Leishmaniasis (ATL) which is part of the complex of diseases caused by protozoan parasites from Leishmania genus, transmitted by sand fly vectors. As a neglected disease, much effort is still needed in treatment and diagnosis. Currently, ATL diagnosis is mainly made by parasite detection by microscopy. The sensitivity of the method varies, and factors such ...
Tópico(s): Trypanosoma species research and implications
2020 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Aymbiré Angeletti da Fonseca, Danilo Andrade Santos, Renato Ribeiro Passos, Felipe Vaz Andrade, Otacílio José Passos Rangel,
Abstract The low efficiency of phosphorus fertilization in weathered soils can limit plant development. The application of biochars in these areas has been seen as an important way to increase the efficiency of phosphorus fertilization and to promote better plant growth. However, biochars are alkaline materials that can increase soil pH and thus change the nutrient dynamics, which has been often ignored in studies of this nature. Here, all treatments had their pH standardized at 6.1 to eliminate ...
Tópico(s): Soil Management and Crop Yield
2020 - Wiley | Soil Use and Management
Produção Nacional
Revisado por pares
Fernanda Faot, Amália Machado Bielemann, Alessandra Juliê Schuster, Raissa Micaella Marcello‐Machado, Altair Antoninha Del Bel Cury, Gustavo G. Nascimento, Otacílio Luiz Chagas Júnior,
To evaluate the influence of primary insertion torque (IT) values of narrow dental implants on the peri-implant health, implant stability, immunoinflammatory responses, bone loss, and success and survival rates.Thirty-one edentulous patients received two narrow implants (2.9x10mm, Facility NeoPoros) to retain mandibular overdentures. The implants were categorized in four groups according to their IT: (G1) IT > 10 Ncm; (G2) IT ≥ 10Ncm and ≤ 30 Ncm; (G3) IT >30Ncm and < 45Ncm; (G4) IT ≥ 45Ncm, and all implants were ...
Tópico(s): Periodontal Regeneration and Treatments
2019 - Hindawi Publishing Corporation | BioMed Research International
Produção Nacional
Revisado por pares
Eliane Macedo Sobrinho Santos, Anna Christina de Almeida, Hércules Otacílio Santos, Alex Sander Rodrigues Cangussu, Kattyanne Souza Costa, Janainne Nunes Alves, Luiz Carlos Bertucci Barbosa, Raimundo Wagner de Souza Aguiar,
Bovine mastitis affects dairy cattle worldwide and, despite the existing therapeutic measures, is not totally under control, leading to the need to develop alternative strategies. Brassica oleracea is a phytochemical commonly used in the control and prevention of human and animal diseases. The use of this plant in the treatment of infectious bovine mastitis has been little referenced in the literature and its molecular mechanism of action in this disease has not been clarified yet. This study aimed ...
Tópico(s): Aquaculture disease management and microbiota
2019 - Elsevier BV | Microbial Pathogenesis
Produção Nacional
Revisado por pares
Roberto Rodrigues Ferreira, Rayane da Silva Abreu, Gláucia Vilar-Pereira, Wim Degrave, Marcelo Meuser-Batista, Nilma Valéria Caldeira Ferreira, Otacílio C. Moreira, Natália Lins da Silva Gomes, Elen Mello de Souza, Isalira Peroba Ramos, Sabine Bailly, Jean‐Jacques Feige, Joseli Lannes-Vieira, Tânia Cremonini de Araújo-Jorge, Mariana Caldas Waghabi,
TGF-β involvement in Chagas disease cardiomyopathy has been clearly demonstrated. The TGF-β signaling pathway is activated in the cardiac tissue of chronic phase patients and is associated with an increase in extracellular matrix protein expression. The aim of this study was to investigate the effect of GW788388, a selective inhibitor of TβR1/ALK5, on cardiac function in an experimental model of chronic Chagas' heart disease. To this end, C57BL/6 mice were infected with Trypanosoma cruzi (102 parasites ...
Tópico(s): Signaling Pathways in Disease
2019 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Iaci Menezes Penteado, Ana Claudeíse Silva do Nascimento, Dávila Suelen Souza Corrêa, Edila Arnaud Ferreira Moura, Roberto Zilles, Maria Cecília Rosinski Lima Gomes, Felipe Jacob Pires, Otacílio Soares Brito, Josenildo Frazão da Silva, Ademir Vilena Reis, A. dos S. Souza, Amanda Cristina Nunes Pacífico,
Using Actor-Network Theory, this article analyzes the process by which a solar-powered food storage technology was implemented in an isolated floodplain community in the Brazilian Amazon (Amazonas state, Brazil), as part of the Solar Ice Project headed by the Mamirauá Institute for Sustainable Development. Our study describes the sociotechnical network that entangles the human and nonhuman actors involved in this initiative and reflects on the complexity of the implementation process. Our discussion ...
Tópico(s): Innovative Human-Technology Interaction
2019 - Elsevier BV | Energy Research & Social Science
Produção Nacional
Revisado por pares
Susana Portillo, Brenda G. Zepeda, Eva Iniguez, Janet J. Olivas, Nasim H. Karimi, Otacílio C. Moreira, Alexandre F. Marques, Katja Michael, Rosa A. Maldonado, Igor C. Almeida,
Chagas disease (ChD), caused by the hemoflagellate parasite Trypanosoma cruzi, affects six to seven million people in Latin America. Lately, it has become an emerging public health concern in nonendemic regions such as North America and Europe. There is no prophylactic or therapeutic vaccine as yet, and current chemotherapy is rather toxic and has limited efficacy in the chronic phase of the disease. The parasite surface is heavily coated by glycoproteins such as glycosylphosphatidylinositol (GPI)- ...
Tópico(s): Toxin Mechanisms and Immunotoxins
2019 - Nature Portfolio | npj Vaccines
Produção Nacional
Revisado por pares
João Cláudio Machado, Daniel Barreira, Israel Teoldo, Bruno Travassos, João Bosco Júnior, João Otacílio Libardoni dos Santos, Alcides José Scaglia,
Purpose: This study aimed to investigate if player tactical skill level and age category influence team performance and player exploratory behavior in tasks with different difficulty levels. Method: In total, 48 youth male soccer players participated in the study (U15, n = 24, mean age = 13.06 ± 1.53 years; U17, n = 24, mean age = 16.89 ± 0.11 years). Player tactical skills were evaluated through the System of Tactical Assessment in Soccer (FUT-SAT), allowing them to be organized into three groups according to ...
Tópico(s): Sports injuries and prevention
2019 - Taylor & Francis | Research Quarterly for Exercise and Sport
Produção Nacional
Francisca Hildemagna Guedes da Silva, Denise da Gama Jaén Batista, Cristiane França da Silva, Beatriz Philot Pavão, Marcos Meuser Batista, Otacílio C. Moreira, Letícia R. Q. Souza, Constança Britto, Girish Rachakonda, Fernando Villalta, Galina I. Lepesheva, Maria de Nazaré Correia Soeiro,
Up to now, no vaccines are available for Chagas disease, and the current therapy is largely unsatisfactory. Novel imidazole-based scaffolds of protozoan sterol 14α-demethylase (CYP51) inhibitors have demonstrated potent antiparasitic activity with no acute toxicity. Presently our aim was to investigate the effectiveness of the experimental 14α-demethylase inhibitor VFV in the mouse models of Trypanosoma cruzi infection using a naturally drug-resistant Colombiana strain, under monotherapy and in association ...
Tópico(s): Research on Leishmaniasis Studies
2019 - American Chemical Society | ACS Infectious Diseases
Produção Nacional
Revisado por pares
Rita de Cássia Pontello Rampazzo, Ana Cláudia Graziani, Keren Kariene Leite, Jhully Anni Surdi, Cheysa A. Biondo, Maykon L.N. Costa, Thiago Jacomasso, Marco Cereda, Marco Fazio, M Bianchessi, Otacílio C. Moreira, Constança Britto, Joana D’Arc Neves Costa, Viviane Monteiro Góes, Alexandre J. da Silva, Marco Aurélio Krieger, Alexandre Dias Tavares Costa,
Although molecular diagnostics is well established in clinical laboratories, its full potential has not been extended to field settings. Typically, diagnostic real-time quantitative PCR (qPCR) reagents require temperature-controlled transportation and storage. Furthermore, thermocyclers are bulky and fragile, requiring good infrastructure for optimal operation. These major hurdles strongly limit use of molecular-based tests in low-resource scenarios. Herein, Trypanosoma cruzi or Plasmodium spp. DNA ...
Tópico(s): Parasitic Diseases Research and Treatment
2019 - Elsevier BV | Journal of Molecular Diagnostics
Ranit Mukherjee, Mohammad Habibi, Ziad T. Rashed, Otacilio Berbert, Xiangke Shi, Jonathan B. Boreyko,
Porous surfaces impregnated with a liquid lubricant exhibit minimal contact angle hysteresis with immiscible test liquids, rendering them ideal as self-cleaning materials. Rather than roughening a solid substrate, an increasingly popular choice is to use an absorbent polymer as the "porous" material. However, to date the polymer choices have been limited to expensive silicone-based polymers or complex assemblies of polymer multilayers on functionalized surfaces. In this paper, we show that hydrocarbon- ...
Tópico(s): Adhesion, Friction, and Surface Interactions
2018 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Daniella Alchaar D’Ávila, Lúcia Maria da Cunha Galvão, Giovane Rodrigo Sousa, Constança Britto, Otacílio C. Moreira, Égler Chiari,
Background Despite the improvements in diagnostic tools for detection of Trypanosoma cruzi in human blood samples, the isolation of parasite from bloodstream in the chronic phase of Chagas disease is challenging. Thus, there is an increasing interest in the development of strategies that allow an accurate monitoring of the parasite load in bloodstream of Chagas disease patients. Given that, the comparison of a classical diagnostic method such as blood culture and multiplex quantitative real-time ...
Tópico(s): Insect symbiosis and bacterial influences
2018 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Ícaro Rodrigues-dos-Santos, Myllena F. A. D. Melo, Liane de Castro, Alejandro Marcel Hasslocher‐Moreno, Pedro Emmanuel Alvarenga Americano do Brasil, Andréa Silvestre de Sousa, Constança Britto, Otacílio C. Moreira,
Chagas disease is still a major public health issue in many Latin American countries. One of the current major challenges is to find an association between Trypanosoma cruzi discrete typing units (DTUs) and clinical manifestations of the disease. In this study, we used a multilocus conventional PCR and quantitative real time PCR (qPCR) approaches to perform the molecular typing and parasite load quantification directly from blood specimens of 65 chronic Chagas disease patients. All patients were recruited ...
Tópico(s): Research on Leishmaniasis Studies
2018 - Public Library of Science | PLoS neglected tropical diseases