Produção Nacional
Revisado por pares
Vanessa Cristine de Souza Carneiro, Soniza Vieira Alves‐Leon, Dmitry José de Santana Sarmento, Wagner Luís da Costa Nunes Pimentel Coelho, Otacílio C. Moreira, Andreza Lemos Salvio, Carlos Henrique Ferreira Ramos, Carlos Henrique Ferreira Ramos Filho, Carla Augusta Barreto Marques, João Paulo da Costa Gonçalves, Luciane Almeida Amado Leon, Vanessa Salete de Paula,
Abstract Background Certain clinical manifestations of coronavirus disease (COVID-19) mimic those associated with human herpesvirus (HHV) infection. In this study, we estimated the prevalence of herpesvirus in patients with COVID-19 and determined if coinfection is associated with poorer outcomes and neurological symptoms. Methods We analyzed samples of 53 patients diagnosed with COVID-19. The samples were evaluated for the presence of alphaherpesviruses, betaherpesviruses, and gammaherpesviruses, ...
Tópico(s): COVID-19 Clinical Research Studies
2022 - BioMed Central | Virology Journal
Produção Nacional
Revisado por pares
Isabela Resende Pereira, Gláucia Vilar-Pereira, Marques Virgínia, Andréa Silva, Bráulia Costa Caetano, Otacílio C. Moreira, Alexandre V. Machado, Oscar Bruña–Romero, Maurício M. Rodrigues, Ricardo T. Gazzinelli, Joseli Lannes-Vieira,
Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is a prototypical neglected tropical disease. Specific immunity promotes acute phase survival. Nevertheless, one-third of CD patients develop chronic chagasic cardiomyopathy (CCC) associated with parasite persistence and immunological unbalance. Currently, the therapeutic management of patients only mitigates CCC symptoms. Therefore, a vaccine arises as an alternative to stimulate protective immunity and thereby prevent, delay progression ...
Tópico(s): Viral Infections and Immunology Research
2015 - Public Library of Science | PLoS Pathogens
Produção Nacional
Revisado por pares
Beatriz Iandra da Silva Ferreira, Natália Lins Silva-Gomes, Wagner Luís da Costa Nunes Pimentel Coelho, Vanessa Duarte da Costa, Vanessa Cristine de Souza Carneiro, Rafael Lopes Kader, Marisa Pimentel Amaro, Lívia Melo Villar, Fábio Miyajima, Soniza Vieira Alves‐Leon, Vanessa Salete de Paula, Luciane Almeida Amado Leon, Otacílio C. Moreira,
The emergence of the COVID-19 pandemic resulted in an unprecedented need for RT-qPCR-based molecular diagnostic testing, placing a strain on the supply chain and the availability of commercially available PCR testing kits and reagents. The effect of limited molecular diagnostics-related supplies has been felt across the globe, disproportionally impacting molecular diagnostic testing in developing countries where acquisition of supplies is limited due to availability. The increasing global demand ...
Tópico(s): Viral gastroenteritis research and epidemiology
2021 - Public Library of Science | PLoS ONE
Alayna de Araújo Rocha Souza, Maria Audenice Saldanha da Silva, Francilene de Sousa Vieira, Hele Sandra Barbosa Dias, Márcia Regina Souza Batista, Otacílio Tavares Fernandes, Rafael Teles de Lima Cardoso, Inecilda da Costa de Araújo, Maria Laura Sales da Silva Matos, Sayonara Nagle da Silveira Carvalho,
Objetivo: Analisar de forma descritiva o monitoramento do câncer de colo de útero no município de São Mateus do Maranhão. Métodos: Ressalta-se que a pesquisa se constitui de um estudo descritivo, de natureza quantitativa, com base me pesquisas realizadas na Coordenação do Programa de Atenção à Saúde da Mulher do Município de São Mateus do Maranhão –MA, bibliotecas digitais. Resultados: A maioria das mulheres que realizou o citopatológico possuía idades de 25 a 29 anos (160 mulheres), o que mostra ...
Tópico(s): Science and Education Research
2018 - Revista Eletronica Acervo Saude | Revista Eletrônica Acervo Saúde
Produção Nacional
Revisado por pares
Vanessa Cristine de Souza Carneiro, Otacílio C. Moreira, Wagner Luís da Costa Nunes Pimentel Coelho, Beatriz Chan Rio, Dmitry José de Santana Sarmento, Andreza Lemos Salvio, Soniza Vieira Alves‐Leon, Vanessa Salete de Paula, Luciane Almeida Amado Leon,
Human herpesviruses (HHVs) can establish latency and be reactivated, also are neurotropic viruses that can trigger neurological disorders. HHV-6 is a herpesvirus that is associated with neurological disorders. Studies have reported the detection of HHV-6 in patients with COVID-19 and neurological manifestations. However, specific diagnoses of the neurological disorders caused by these viruses tend to be invasive or difficult to interpret. This study aimed to establish a relationship between miRNA ...
Tópico(s): Extracellular vesicles in disease
2023 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Produção Nacional
Revisado por pares
Lucas Lima Da, Luciane Almeida Amado Leon, Otacilio Da Cruz, Wagner Luis Da Costa Nunes Pimentel, Vanessa Duarte, Claudia Alexandra Pontes, Lia Lewis Laura, Vanessa Salete, Bárbara Vieira, Livia Villar Melo,
Covid-19 presents as a multisystemic disease with described liver impact. MicroRNAs (miRNAs) are small non- coding RNAs which regulate different pathological processes, including hepatic conditions associated with SARS-CoV-2 infection. This study aimed to investigate serum miRNAs expression in patients with liver diseases according to the presence of SARS-CoV-2 infection. Serum were obtained from 70 individuals from 4 groups: (i) hepatitis/Covid-19 (n=11); (ii) hepatitis-only (n=20); (iii) Covid- 19-only ( ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2024 - Elsevier BV | Annals of Hepatology
Produção Nacional
Igor Cardoso Costa, Marineide Jardim Rodrigues, Jeanne Vieira Soares, Diego Alves Souza, Eliane Macedo Sobrinho Santos, Hércules Otacílio Santos, Kattyanne de Souza Costa,
Resumo : O trabalho teve como objetivo relatar a experiencia dos alunos do 5° periodo do Curso de Tecnologia em Gestao Ambiental do IFNMG – Campus Aracuai em elaborar artigos cientificos de revisao sistematica de literatura, que e uma investigacao de cunho cientifico, e, consequentemente, apresenta-los em formato de posteres. Esta apresentacao ocorreu na I Mostra de Artigos Cientificos da Gestao Ambiental que foi idealizada e organizada como parte das exigencias da disciplina de Metodologia Cientifica. ...
Tópico(s): Business and Management Studies
2017 - | Caderno de Ciências Agrárias
Credigar Gonçalves Moreira, Aline Marchiori Crespo, Geisa Corrêa Louback, Maurício Novaes Souza, Aparecida de Fátima Madella de Oliveira, Bruno de Lima Preto, Ana Cláudia Hebling Meira, Otacílio José Passos Rangel, Ana Paula Cândido Gabriel Berilli, Roberta Cunha Vieira, Rodrigo Leonardo de Paula Dias Mendonça, Taís Neves Calabianqui, Natália Cassa Feleti, Larissa Guilhermina Campos Cardozo, Abel Lopes Costa,
O córrego Horizonte, localizado no distrito de Rive, Alegre- ES, é mais um dos cursos hídricos que foram poluídos em decorrência da ausência de uma visão sustentável do ambiente. Devido à falta da aplicabilidade de políticas públicas, quanto de priorização na utilização de recursos, tornam-se necessárias a adoção de medidas de proteção ambiental voltadas para esse recurso hídrico, sendo uma das alternativas, o Pagamento por Serviços Ambientais (PSA), que consiste no reconhecimento de boas práticas ...
Tópico(s): Environmental Sustainability and Education
2024 - Servicios Academicos Intercontinentales | OBSERVATÓRIO DE LA ECONOMÍA LATINOAMERICANA
Produção Nacional
Revisado por pares
Daiany Augusta Paes Martins, Ana Carla Lanzarini, Carine Farias Heinz, Francielle Santos Vieira, Rafael Angelo Bonatto, Maria Raquel Kanieski,
... solo de um fragmento florestal no município de Otacílio Costa, SC, com a finalidade de avaliar a viabilidade ...
Tópico(s): Geography and Environmental Studies
2017 - UNIVERSIDADE FEDERAL DO PARANÁ | FLORESTA
Produção Nacional
Revisado por pares
Marcelo Meuser-Batista, José R. Corrêa, Vinícius Frias Carvalho, Constança Britto, Otacílio C. Moreira, Marcos Meuser Batista, Maurílio José Soares, Francisco Alves Farias Filho, Patrı́cia Silva, Joseli Lannes-Vieira, Robson Coutinho‐Silva, Andrea Henriques‐Pons,
Although the roles of mast cells (MCs) are essential in many inflammatory and fibrotic diseases, their role in Trypanosoma cruzi–induced cardiomyopathy is unexplored. In this study, we treated infected CBA mice with cromolyn, an MC stabilizer, and observed much greater parasitemia and interferon-γ levels, higher mortality, myocarditis, and cardiac damage. Although these data show that MCs are important in controlling acute infection, we observed MC apoptosis in the cardiac tissue and peritoneal cavity ...
Tópico(s): Trypanosoma species research and implications
2011 - Elsevier BV | American Journal Of Pathology
Produção Nacional
Revisado por pares
Luciane Almeida Amado Leon, Wagner Luís da Costa Nunes Pimentel Coelho, Arthur Daniel Rocha Alves, Vanessa Cristine de Souza Carneiro, Otacílio C. Moreira, Vanessa Salete de Paula, Andreza Lemos Salvio, Larissa Araújo Duarte, Elisa Gouvea Gutman, Fabrícia Lima Fontes-Dantas, João Paulo da Costa Gonçalves, Carlos Henrique Ferreira Ramos, Carlos Henrique Ferreira Ramos Filho, Marta Guimarães Cavalcanti, Marisa Pimentel Amaro, Rafael Lopes Kader, Roberto de Andrade Medronho, Dmitry José de Santana Sarmento, Soniza Vieira Alves‐Leon,
Since COVID-19 was declared a pandemic, Brazil has become one of the countries most affected by this disease. A year into the pandemic, a second wave of COVID-19 emerged, with a rapid spread of a new SARS-CoV-2 lineage of concern. Several vaccines have been granted emergency-use authorization, leading to a decrease in mortality and severe cases in many countries. However, the emergence of SARS-CoV-2 variants raises the alert for potential new waves of transmission and an increase in pathogenicity. ...
Tópico(s): Long-Term Effects of COVID-19
2023 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Evaristo Villalba‐Alemán, Mariáurea Matias Sarandy, Mônica Morais‐Santos, Rômulo Dias, Vilela Gonçalves, Marianne Rocha-Hasler, Jemima Araujo, Raiza Brandão Peres, P Da Silva, Marcos Meuser Batista, L De Azevedo, Maria de Lourdes Bastos, Mirleide Chaar Bahia, Núbia Boechat, Maria de Nazaré Correia Soeiro, Priscilla L. Zangrandi, André Faria Mendonça, Ariovaldo Pereira, Rudy Boonstra, Emerson Monteiro Vieira, Diana Minardi, David J. Studholme, Birgit Oidtmann, Tobia Pretto, Mark van der Giezen, Håkon Holand, Henrik Jensen, Thomas Kvalnes, Jarle Tufto, Henrik Pärn, BE Sæther, Thor Harald Ringsby, Justyna Kubacka, Alina Gerlée, Julien Foucher, Judith Korb, Edyta Podmokła, Seyma Kilinc, Harun Kaya, Sami Şimşek, M. C. ROCHA, Constança Britto, Cynthia Machado Cascabulho, Gabriel de., Melo Oliveira, Aline Nefertiti da Gama, Cristiane França da Silva, Karine Lima da Costa, Paula Araújo, Jerônimo Diego, Souza Campos, Cristina Kelly, Otacílio Demarque, Cruz Da, Helena Moreira, Correia De Nazaré, César Gómez‐Hernández, Sergio G. Pérez, Karine Rezende-Oliveira, Cecília de Aquino Barbosa, Eliane Lages-Silva, Luı́s Eduardo Ramı́rez, Juan David Ramírez, Karina M. Rebello, Lívia Almeida Uehara, Vítor Ennes-Vidal, Aline dos Santos Garcia-Gomes, Patrı́cia Azambuja, Rubem F. S. Menna‐Barreto, André Luis Souza dos Santos, Marta H. Branquinha, Avila-Levy, Therese A. Catanach, Kevin P. Johnson, Ben Marks, Robert G. Moyle, Michel P. Valim, Jason D. Weckstein, Mélanie Clerc, Andy Fenton, Simon A. Babayan, Amy B. Pedersen, Brenda Solórzano‐García, Amanda Melin, Filippo Aureli, Gerardo Pérez‐Ponce de León,
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2019 - Cambridge University Press | Parasitology