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Artigo Acesso aberto Revisado por pares

Deborah L. Stone, Amanda K. Ombrello, Juan I. Aróstegui, Corinne Schneider, Vinh Dang, Adriana de Jesus, Charlotte Girard, Cem Gabay, Wonyong Lee, Jae Jin Chae, Ivona Aksentijevich, Raphaela Goldbach‐Mansky, Daniel L. Kastner, Scott Canna,

... cause a spectrum of autoinflammatory manifestations epitomized by PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome.). The connections between PSTPIP1 and PAPA syndrome are poorly understood, although evidence suggests involvement ... to investigate an association of IL-18 with PAPA syndrome.Clinical and genetic data and serum samples ... referred to institutions due to symptoms indicative of PAPA syndrome. Serum IL-18, IL-18 binding protein ( ... assay.The symptoms of PSTPIP1-positive patients with PAPA syndrome overlapped with those of mutation-negative patients ...

Tópico(s): IL-33, ST2, and ILC Pathways

2021 - Wiley | Arthritis & Rheumatology

Livro

Project Gutenberg

Artigo Revisado por pares

Yuqing Zhou, Yue Gao, Huiliang Wang, Minggui Xia, Qinyan Yue, Zhiyong Xue, Junjiang Zhu, Junxia Yu, Weiyan Yin,

... 3D reduced graphene oxide/poly(amino-phosphonic acid) (PAPA) aerogels (rGO/PAPAs) with different PAPA content were developed by solvothermal reduction of the graphene oxide and cross-linking with PAPA chain, and subsequently employed as versatile adsorbent for ... of the reduced graphene oxide (rGO) sheet and PAPA component, as well as its unique 3D structure, the resultant aerogel (rGO/PAPA-2) gained amphiphilic, ultralight, and multifunctional properties. Thus, ... groups. The uptake of Cr(III) by rGO/PAPA-2 was fitted well with the Langmuir isotherm ...

Tópico(s): Graphene research and applications

2021 - Elsevier BV | The Science of The Total Environment

Carta Acesso aberto Revisado por pares

Andrea Carugno, Daniele Gambini, Francesca Raponi, Pamela Vezzoli, Elisa Robustelli Test, Marco Arosio, Annapaola Callegaro, Paolo Sena,

... org/0000-0002-8231-2205 Dermatology Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, Italy Correspondence Andrea Carugno, Dermatology Unit, ASST Papa Giovanni XXIII Hospital, Piazza OMS, 1 Bergamo (BG), ... Mario Gambini, Daniele Mario Gambini Dermatology Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, ItalySearch for more papers ... this authorFrancesca Raponi, Francesca Raponi Dermatology Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, ItalySearch for more papers ... org/0000-0001-8401-081X Dermatology Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, ItalySearch for more papers ...

Tópico(s): Autoimmune and Inflammatory Disorders Research

2020 - Wiley | Dermatologic Therapy

Documentos governamentais Acesso aberto

Printed copy of a papal document which contains an account of the martyrdom of the Dominican missionaries Jacinto Castañeda and Vicente de la Paz in China; and ...

1776 - Gale Group | World Scholar Latin America

Carta Acesso aberto Revisado por pares

Andrea Carugno, Francesca Raponi, Andrea G. Locatelli, Pamela Vezzoli, Donatella Gambini, Marco Di Mercurio, Elisa Robustelli Test, Paolo Sena,

... org/0000-0002-8231-2205 Dermatology Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, Italy Correspondence: A. Carugno. ... this authorF. Raponi, F. Raponi Dermatology Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, ItalySearch for more papers ... G. Locatelli, A.G. Locatelli Dermatology Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, ItalySearch for more papers ... this authorP. Vezzoli, P. Vezzoli Dermatology Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, ItalySearch for more papers ... M. Gambini, D.M. Gambini Dermatology Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, ItalySearch for more papers ...

Tópico(s): Allergic Rhinitis and Sensitization

2020 - Wiley | Journal of the European Academy of Dermatology and Venereology

Livro

Alexander Street

Primary Document Acesso aberto

Book.

1980 - Gale Group | World Scholar Latin America

Artigo Acesso aberto Revisado por pares

Pragnesh Mistry, Carmelo Carmona‐Rivera, Amanda K. Ombrello, Patrycja Hoffmann, Nickie Seto, Anne Jones, Deborah L. Stone, Faiza Naz, Philip M. Carlucci, Stefania Dell’Orso, Gustavo Gutierrez-Cruz, Hong‐Wei Sun, Daniel L. Kastner, Ivona Aksentijevich, Mariana J. Kaplan,

Objectives Pyogenic arthritis, pyoderma gangrenosum and acne (PAPA) syndrome is characterised by flares of sterile arthritis with neutrophil infiltrate and the overproduction of interleukin (IL)-1β. The purpose of this study ... neutrophil extracellular traps (NET) in the pathogenesis of PAPA. Methods Neutrophils and low-density granulocytes (LDG) were ... cytometry. Circulating NETs were measured by ELISA and PAPA serum was tested for the ability to degrade NETs. The capacity of NETs from PAPA neutrophils to activate macrophages was assessed. Skin biopsies ...

Tópico(s): Immune Response and Inflammation

2018 - BMJ | Annals of the Rheumatic Diseases

Livro

Alexander Street

Documentos governamentais Acesso aberto

Printed copy of a document dealing with a request by King Philip V that the Peruvian Catholic Church contribute one million ducats of silver to help cover the ...

1721 - Gale Group | World Scholar Latin America

Artigo Acesso aberto Revisado por pares

Behrouz Mohammadi Nargesi, Natalie Trachtmann, Georg A. Sprenger, Jung-Won Youn,

... aromatic amino acid, p-amino-L-phenylalanine (L-PAPA) is a high-value product with a broad field of applications. In nature, L-PAPA occurs as an intermediate of the chloramphenicol biosynthesis ... grafting approaches to result in an improved L-PAPA producing strain.Escherichia coli K-12 cells were genetically engineered for the production of L-PAPA from glycerol as main carbon source. To do ... ca. 43 ± 2 mg l-1 of L-PAPA from 5 g l-1 glycerol. By expression ... in a tyrR deletion strain, an improved L-PAPA producer was obtained which gave a titer of ...

Tópico(s): Bacterial Genetics and Biotechnology

2018 - BioMed Central | Microbial Cell Factories

Artigo Acesso aberto Revisado por pares

Emily E. Wroblewski, Lisbeth A. Guethlein, Paul J. Norman, Yingying Li, Shawna C. Willey, Alex S. Han, Jean-Bosco N. Ndjango, Steve Ahuka‐Mundeke, Alexander V. Georgiev, Martine Peeters, Beatrice H. Hahn, Peter Parham,

... on the human condition. We defined polymorphism of Papa-B, the bonobo ortholog of HLA-B, for six wild bonobo populations. Sequences for Papa-B exon 2 and 3 were determined from ... fecal samples, minimally representing 110 individuals. Twenty-two Papa-B alleles were defined, each encoding a different Papa-B protein. No Papa-B is identical to any chimpanzee Patr-B, ... chimpanzee, and gorilla. Bonobo populations have 3-14 Papa-B allotypes. Three Papa-B are in all populations, and they are ... having neither epitope. For population Malebo, these three Papa-B are the only Papa-B allotypes. Although ...

Tópico(s): Reproductive System and Pregnancy

2017 - American Association of Immunologists | The Journal of Immunology

Primary Document Acesso aberto

Nuzzi, Ferdinando, Gabrielli, Angelo, marchese, Rezzonico, Carlo,

"Con licenza de' superiori." Also filmed as item no. 12400.6. Book.

0000 - Gale Group | The Making of Modern World

Artigo Acesso aberto Revisado por pares

Vaheshta Sethna, Emily Perry, Jill Domoney, Jane Iles, Lamprini Psychogiou, Natasha E.L. Rowbotham, Alan Stein, Lynne Murray, Paul Ramchandani,

... their young children. La calidad de las interacciones papá-niño se ha convertido en el enfoque de ... niño. Examinamos la potencial contribución de las interacciones papá-niño a los 3 y a los 24 ... usaron las medidas de observación de las interacciones papá-niño a los 3 y a los 24 ... de la crianza en el caso de los papás (n = 192). A los 24 meses, el Índice ... del infante y sensibilidad materna. Los niños cuyos papás presentaban conductas más despegadas y depresivas en las interacciones papá-infante a los 3 meses, obtuvieron un puntaje ...

Tópico(s): Child and Adolescent Psychosocial and Emotional Development

2017 - Wiley | Infant Mental Health Journal

Primary Document Acesso aberto

Adélia Carvalho,

Book.

1979 - Gale Group | World Scholar Latin America

Artigo Acesso aberto Revisado por pares

C. Ross Schmidtlein, Yizun Lin, Si Li, Andrzej Król, Bradley J. Beattie, John L. Humm, Yuesheng Xu,

Purpose Performance of the preconditioned alternating projection algorithm ( PAPA ) using relaxed ordered subsets ( ROS ) with a non‐ ... data is introduced. Methods A ROS version of PAPA with HOTV penalty ( ROS ‐ HOTV ‐ PAPA ) for PET image reconstruction was developed and implemented. ... per support voxel were reconstructed using ROS ‐ HOTV ‐ PAPA . The patients’ brain and whole body PET data ... of‐fight and were reconstructed using ROS ‐ HOTV ‐ PAPA and available clinical ordered‐subset expectation‐maximization ( OSEM ) ... convergence rates were also investigated. Results ROS ‐ HOTV ‐ PAPA converged rapidly, in comparison to non‐ ROS ‐ HOTV ‐ ...

Tópico(s): MRI in cancer diagnosis

2017 - Wiley | Medical Physics

Livro

Project Gutenberg

Documentos governamentais Acesso aberto

Printed copy of a papal document which contains an account of the martyrdom of the Dominican missionaries Jacinto Castañeda and Vicente de la Paz in China; and ...

1776 - Gale Group | World Scholar Latin America

Errata Acesso aberto Revisado por pares

Qing He, Feng Wang, Shiheng Liu, Deyu Zhu, Hengjiang Cong, Fei Gao, Bingqing Li, Hongwei Wang, Lin Zong, Jun Liao, Lichuan Gu,

... water molecule between the two Mn2+ ions and pApA-like molecule. In molecule B, water molecule is ... two AMPs (Fig. 10). As a precaution, both pApA and AMP were fitted in the active site ... be predominant in molecule B and that a pApA fits into the electron density better than two ... even though molecule A contains a mixture of pApA and AMP, pApA still outweighs AMP (Fig. 11). Thus, in the final model, a pApA is placed in the active site of molecule ... ray diffraction data collection and refinement statisticsRv2837c-C/pApA, AMPData collectionWavelength (Å)0.9791Space groupP212121Unit cell parametersa, ...

Tópico(s): Chemical Reactions and Isotopes

2016 - Elsevier BV | Journal of Biological Chemistry