Gustave Silbermann, M. F. L. De Laporte, M. Aug. Chevrolat, M. Aug. Chevrolat, M. F. L. De Laporte, M. Duponchel, L. P. Cantener, Charles Geyer, G. Silbermann, B. W. Westermann, M. F. L. De Laporte, A. Kefebstein, A. Keferstein, E. F. Germar, M. Le Comte Mannerheim, G. Cuvier,
... James Francis Stephens, Gen. Monochamus, Megerle Tridentatus, Chevrolat.— Pl. 7, M. Zimmermann, De Halle, a Publié Une Monographie ...
1833 - Gale Group | NCCO-STM 1of2
Yoshioki Yamasaki, Hidehiro Yamada, Toshiko Nozaki, Jun Akaogi, Cody Nichols, Robert Lyons, Anthony Chin Loy, Edward K. L. Chan, Westley H. Reeves, Minoru Satoh,
... RNA synthetases, such as histidyl (Jo‐1), threonyl (PL‐7), alanyl (PL‐12), glycyl (EJ), and isoleucyl (OJ), ... studies, including studies of Japanese subjects. However, anti–PL‐7 was found in 17% of patients, in contrast ... P < 0.02–0.0002). The 6 anti–PL‐7–positive patients were not related, and no skewing ... of antisynthetase‐positive patients. The patients with anti–PL‐7 had lower serum muscle enzyme levels and milder ... with anti–Jo‐1–positive patients. Conclusion Anti–PL‐7 was found at an unusually high frequency in ...
Tópico(s): Muscle Physiology and Disorders
2006 - Wiley | Arthritis & Rheumatism
Ane Labirua‐Iturburu, Albert Selva-O’Callaghan, Melinda Vincze, Katalin Dankó, Jiří Vencovský, Benjamin A. Fisher, P. Charles, Maryam Dastmalchi, Ingrid E. Lundberg,
... patients with myositis; anti-threonyl-tRNA synthetase (anti-PL-7) is one of the rarest. We describe the ... laboratory characteristics of a cohort of European anti-PL-7 patients, and compare them with previously reported cases. This multicenter study of patients positive for anti-PL-7, identified between 1984 and 2011, derives from the ... exact tests. Eighteen patients, 15 women, were anti-PL-7 antibody positive. Median follow-up was 5.25 ... literature review the most common manifestations of anti-PL-7 antisynthetase syndrome were interstitial lung disease (77%), myositis ( ...
Tópico(s): Viral Infections and Immunology Research
2012 - Wolters Kluwer | Medicine
M Tomonaga, Noriho Sakamoto, Yuji Ishimatsu, Tomoyuki Kakugawa, Tatsuhiko Harada, Shota Nakashima, Atsuko Hara, Shintaro Hara, Yoshihiro Horai, Atsushi Kawakami, Hiroshi Mukae, Shigeru Kohno,
Anti-PL-7 is an anti-tRNA synthetase antibody, and interstitial lung disease (ILD) is the most frequent complication of anti-PL-7-associated antisynthetase syndrome. However, the features of ILD ... and 15 patients who were positive for anti-PL-7 and anti-Jo-1 antibodies, respectively. The features ... higher in the Jo-1 than in the PL-7 group. High-resolution computed tomography revealed nonspecific interstitial pneumonia in all patients in the PL-7 group and organizing pneumonia in four of the ... pulmonary complications slightly differ between patients expressing anti-PL-7 and anti-Jo-1 antibodies. Further studies are ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
2014 - Springer Science+Business Media | Lung
Akira Inoue, Chieco Mashino, Toshiki Uji, Naotsune Saga, Koji Mikami, Takao Ojima,
Alginate lyases belonging to polysaccharide lyase family-7 (PL-7) are the most well studied on their structures ... functions among whole alginate lyases. However, all characterized PL-7 alginate lyases are from prokaryotic bacteria cells. Here we report the first identification of eukaryotic PL-7 alginate lyase from marine red alga Pyropia yezoensis. ... of bacterial characterized alginate lyases classified into family PL-7. Recombinant PyAly protein, rPyAly, which was produced with ... PyAly is an endolytic alginate lyase belonging to PL-7. Moreover, we found that the PyAly gene is ...
Tópico(s): Algal biology and biofuel production
2015 - | Current Biotechnology
Produção Nacional
Fernando Henrique Carlos de Souza, Marcela Gran Pina Cruellas, Maurício Levy‐Neto, Samuel Katsuyuki Shinjo,
... pacientes com síndrome antissintetase (SAS) do tipo anti-PL-7, PL-12 e EJ. Estudo de coorte, retrospectivo, envolvendo 20 pacientes com SAS (8 com anti-PL-7, 6 com PL-12, 6 com EJ), em ... ocasião do diagnóstico da doença. A SAS (anti-PL-7, PL-12 e EJ) afetou predominantemente mulheres brancas. ... of a series of patients with the anti-PL-7, PL-12 and EJ types of antisynthetase syndrome ( ... of 20 patients with ASS (8 with anti- PL-7, 6 with PL-12, 6 with EJ) monitored ... cancer at the time of diagnosis. ASS (anti-PL-7, PL-12 and EJ) was found to predominantly ...
Tópico(s): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
2013 - Elsevier BV | Revista Brasileira de Reumatologia
Ira N. Targoff, Frank C. Arnett, Morris Reichlin,
... clinical correlations of antithreonyl–transfer RNA synthetase (anti–PL‐7), as well as the relationship of anti–PL‐7 to anti–histidyl–transfer RNA synthetase (anti–Jo‐ ... threonine aminoacylation was used to screen for anti–PL‐7. Sera from 3 patients, 2 with polymyositis and ... dermatomyositis, which was previously found to contain anti–PL‐7, inhibited >90% of activity (3.7% of 109 ... enzyme that was either affinity purified with anti–PL‐7 or was biochemically purified. There was no indication ... most sera, by enzyme‐linked immunosorbent assay. Anti–PL‐7 is an uncommon myositis‐associated antibody that is ...
Tópico(s): Neurogenetic and Muscular Disorders Research
1988 - Wiley | Arthritis & Rheumatism
Yasuhito Hamaguchi, Manabu Fujimoto, Takashi Matsushita, Kenzo Kaji, Kazuhiro Komura, Minoru Hasegawa, Masanari Kodera, Eiji Muroi, Keita Fujikawa, Mariko Seishima, Hidehiro Yamada, Ryo Yamada, Shinichi Sato, Kazuhiko Takehara, Masataka Kuwana,
... anti-Jo-1 (36%), anti-EJ (23%), anti-PL-7 (18%), anti-PL-12 (11%), anti-KS (8%), ... for one serum Ab that had both anti-PL-7 and PL-12 reactivity. Myositis was closely associated with anti-Jo-1, anti-EJ, and anti-PL-7, while interstitial lung disease (ILD) was correlated with ... patients with anti-Jo-1, anti-EJ, anti-PL-7, and anti-PL-12. Therefore, most clinical diagnoses ... for anti-Jo-1, anti-EJ, and anti-PL-7; clinically amyopathic DM or ILD for anti-PL- ... with anti-Jo-1, anti-EJ, and anti-PL-7 developed myositis later if they had ILD alone ...
Tópico(s): RNA Research and Splicing
2013 - Public Library of Science | PLoS ONE
Xi Zhan, Wei Yan, Ying Wang, Qing Li, Xuhua Shi, Yanli Gao, Qiao Ye,
... recruited. 33 were JO-1 positive, 30 were PL-7 positive, 23 were EJ positive, 13 were PL- ... difference was observed among the 5 groups. The PL-7 (+) group had a higher frequency of UIP pattern ( ... 78.2%), which was significantly higher than the PL-7 (+) (P < 0.001) and PL-12 (+) groups (P = ... other 3 groups (P < 0.05), and the PL-7 group had the lowest FVC improvement (P < 0. ... other 3 groups (P < 0.05). Conclusion Anti PL-7 antibody had the same frequency as anti-JO- ... to steroid therapies, with or without immunosuppressants. The PL-7 (+) group had the highest occurrence of UIP pattern, ...
Tópico(s): Eosinophilic Disorders and Syndromes
2021 - BioMed Central | BMC Pulmonary Medicine
S. Mazurek, F Hugo, Klaus Failing, E. Eigenbrodt,
... 5.0, and a p36-associated form with pl 7.8. The mitochondrial form comprises the mature mitochondrial ... precursor form (pl 8.9). Refocusing of the pl 7.8 form of malate dehydrogenase also gave rise to the mitochondrial isoenzyme. Thus, the pl 7.8 form of malate dehydrogenase is actually the ... focusing column induced a quantitative shift of the pl 7.8 form of malate dehydrogenase to the mitochondrial ... phosphorylated in tyrosine. Kinetic measurements revealed that the pl 7.8 form of malate dehydrogenase has the lowest ...
Tópico(s): Metabolism and Genetic Disorders
1996 - Wiley | Journal of Cellular Physiology
Masayuki Yamasaki, Satoko Moriwaki, Osamu Miyake, Wataru Hashimoto, Kousaku Murata, Bunzo Mikami,
... and -7 based on their primary structures. Family PL-7 enzymes are still poorly characterized especially in structural properties. Among family PL-7, a gene coding for a hypothetical protein (PA1167) ... specificity. The first crystal structure of the family PL-7 alginate lyase was determined at 2.0 A ... difference between the beta-sandwich PA1167 of family PL-7 and alpha/alpha-barrel AlgL of family PL- ...
Tópico(s): Lipid Membrane Structure and Behavior
2004 - Elsevier BV | Journal of Biological Chemistry
Michael B. Mathews, Morris Reichlin, Graham R.V. Hughes, Robert M. Bernstein,
An autoantibody known as PL-7 was found in the serum of four patients with myositis and one with a systemic lupus erythematosus-like syndrome. The PL-7 antigen is an 80,000 dalton polypeptide that coprecipitates with transfer RNA. In aminoacylation reactions, PL-7 IgG inhibited the charging of tRNA with threonine ... but tRNA was not coprecipitated. We conclude that PL-7 antibody is directed at threonyl-tRNA synthetase, and ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
1984 - Rockefeller University Press | The Journal of Experimental Medicine
Frieda C. Paterson, Philip S. Rudland,
... three polypeptides of molecular weights (MW) 35 kD (pl = 7.7), 45 kD (pl = 7.5) and 33 kD (pl = 7.7) increase dramatically in radioactive abundance. These increases ... 9), 27 kD (pl = 6.2), 30 kD (pl = 7.2), and the same 33 kD polypeptide as ...
Tópico(s): Glycosylation and Glycoproteins Research
1985 - Wiley | Journal of Cellular Physiology
Aryeh Fischer, Jeffrey J. Swigris, Roland M. du Bois, David A. Lynch, Gregory P. Downey, Gregory P. Cosgrove, Stephen K. Frankel, Evans R. Fernández Pérez, Joann Zell Gillis, Kevin K. Brown,
... syndrome based on clinical features and positive anti-PL-7 or PL-12 antibodies.MethodsOver a 24-month ... of other anti-tRS antibodies (seven with anti-PL-7, two with anti-PL-12 antibodies). All presented ... were variable, but some subjects clearly improved.ConclusionAnti-PL-7 and PL-12 antibodies may be more common ... research is needed to advance understanding of anti-PL-7 or anti-PL-12-positive AS syndrome, including ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
2009 - Elsevier BV | Respiratory Medicine
Go Saito, Masato Kono, Akari Tsutsumi, Yu Koyanagi, Koichi Miyashita, Takeshi Kobayashi, Hironao Hozumi, Yoshihiro Miki, Yoshifumi Arai, Yoshiro Otsuki, Dai Hashimoto, Tomoyuki Fujisawa, Tõru Nakamura, Takafumi Suda, Hidenori Nakamura,
... clinical course. She was finally diagnosed with anti-PL-7 antisynthetase syndrome (ASS) based on the presence of anti-PL-7 antibody, and she fulfilled the diagnostic criteria for ... be one of the characteristic features of anti-PL-7 ASS.
Tópico(s): Muscle and Compartmental Disorders
2018 - The Japanese Society of Internal Medicine | Internal Medicine
Produção Nacional
Fernando Henrique Carlos de Souza, Marcela Gran Pina Cruellas, Maurício Levy‐Neto, Samuel Katsuyuki Shinjo,
... of a series of patients with the anti-PL-7, PL-12 and EJ types of antisynthetase syndrome ( ... of 20 patients with ASS (8 with anti-PL-7, 6 with PL-12, 6 with EJ) monitored ... cancer at the time of diagnosis. ASS (anti-PL-7, PL-12 and EJ) was found to predominantly ... pacientes com síndrome antissintetase (SAS) do tipo anti-PL-7, PL-12 e EJ. Estudo de coorte, retrospectivo, envolvendo 20 pacientes com SAS (8 com anti-PL-7, 6 com PL-12, 6 com EJ), em ... ocasião do diagnóstico da doença. A SAS (anti-PL-7, PL-12 e EJ) afetou predominantemente mulheres brancas. ...
Tópico(s): Eosinophilic Disorders and Syndromes
2013 - Elsevier BV | Revista Brasileira de Reumatologia (English Edition)
Taiga Kuga, Yoshiyuki Abe, Masakazu Matsushita, Kurisu Tada, Ken Yamaji, Naoto Tamura,
... be related to idiopathic inflammatory myopathies (IIM). Anti-PL-7 antibody is anti-threonyl-tRNA synthetase antibody associated with antisynthetase syndrome (ASS). Since anti-PL-7 antibody is rare (mostly 1-4% of myositis, ... 1). Objectives To analyze clinical characteristics of anti-PL-7 positive IIM patients. Methods Anti-PL-7 antibody was detected by EUROLINE Myositis Profile 3. ... or Bohan And Peter classification (3). Eleven anti-PL-7 antibody positive adult patients (all female), age at ... complicated with malignancy in this study. Conclusion Anti-PL-7 antibody positive IIM patients frequently complicated with ILD. ...
Tópico(s): Systemic Sclerosis and Related Diseases
2019 - BMJ | Annals of the Rheumatic Diseases
Chi V. Dang, Eng M. Tan, Jolinda A. Traugh,
... analyze the epitopes of threonyl-tRNA synthetase. The PL-7 autoantibody reacted with the native but not the ... denatured forms of the enzyme. In addition, the PL-7 autoantibody specifically inhibited threonyl-tRNA synthetase activity whereas ... on aminoacylation. Thus, the epitopes recognized by the PL-7 autoantibody are formed by the tertiary structure of ...
Tópico(s): RNA Research and Splicing
1988 - Wiley | The FASEB Journal
Yoshioki Yamasaki, Minoru Satoh, Machiko Mizushima, Takahiro Okazaki, Hiroko Nagafuchi, Seido Ooka, Tomohiko Shibata, Hiromasa Nakano, Hitoshi Ogawa, Kohei Azuma, Akihiko Maeda, Kumiko Tonooka, Hiroshi Ito, Yukiko Takakuwa, Makoto Inoue, Hirofumi Mitomi, Tomofumi Kiyokawa, Kosei Tsuchida, Hiromi Matsushita, Hidenori Mikage, Yoshihiko Murakami, Jason Chan, Shoichi Ozaki, Hidehiro Yamada,
... 1%), except for a high prevalence of anti-PL-7 (12%), which allowed us to characterize patients carrying ... 3000 IU/l was less common in anti-PL-7-positive patients (57%) than anti-Jo-1-positive ... 57% in anti-Jo-1, 67% in anti-PL-7) (vs. 21% in anti-ARS-negative, p < 0. ...
Tópico(s): Viral Infections and Immunology Research
2015 - Oxford University Press | Modern Rheumatology
Tomoyuki Fujisawa, Hironao Hozumi, Masato Kono, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, Ran Nakashima, Yoshitaka Imura, Tsuneyo Mimori, Takafumi Suda,
... and a higher positive rate for the anti-PL-7 antibody. Multivariate logistic regression analysis revealed that a positive anti-PL-7 antibody test and a lower %FVC were independently ... long-term follow-up. The presence of anti-PL-7 antibody and a lower %FVC at initial diagnosis ...
Tópico(s): Eosinophilic Disorders and Syndromes
2017 - Elsevier BV | Respiratory Investigation
... well. Here, the preparation of native and recombinant PL-7 alginate lyases and the methods for evaluation of enzymatic activity are summarized. Examples of PL-7 alginate lyase applications are also described.
Tópico(s): Enzyme Production and Characterization
2018 - Academic Press | Methods in enzymology on CD-ROM/Methods in enzymology
Minna Jiang, Xin Dong, Yi Zheng,
... antibodies included anti-Jo-1 (42.86%), anti-PL-7 (26.19%), anti-PL-12 (10.71%), anti- ... positive to antibodies of anti-Jo-1, anti-PL-7, and anti-EJ, organizing pneumonia was the main ... patients with ILD positive to antibodies of anti-PL-7, anti-Jo-1, and anti-EJ. The incidence ...
Tópico(s): Sarcoidosis and Beryllium Toxicity Research
2021 - Wolters Kluwer | Medicine
John W Williams, T. C. Marshall,
... the concentrations of CK) are denoted as a (pl 7.55), b (pl 7.35), c (pl 7.25), d (pl 7.05), e (pl 6.85), f (pl 6. ...
Tópico(s): Cardiac Imaging and Diagnostics
1988 - American Association for Clinical Chemistry | Clinical Chemistry
M. Soledade C. Pedras, Yang Yu,
... of L. maculans. Incorporations of deuterium into sirodesmin PL (7) and its precursor phomamide (4) were determined using ... 2 ]phomamide (4a) were incorporated efficiently into sirodesmin PL (7). Interestingly, an unexpected “twist” revealed that one of ... 1a) was exchanged stereospecifically before incorporation into sirodesmin PL (7). As well, our studies revealed that O-prenyl- ... the first committed precursor en route to sirodesmin PL (7).
Tópico(s): Natural product bioactivities and synthesis
2009 - NRC Research Press | Canadian Journal of Chemistry
... f. wiss. Zool., Bd. 112, S. 239–290, pls. 7, 8. Harvey, E. N. (1914) On the chemical ... the Insecta. Psyche, Vol. 6, pp. 253–258, pl. 7. Williams, F. X. (1915) The luminous organ of ...
Tópico(s): Forest Insect Ecology and Management
1922 - Wiley | Journal of Morphology
... Proc. U.S. nat. Mus. 95: 411–520, pls. 7–17. 10.5479/si.00963801.95-3184.411 ... Öfvers Vetensk. Akad. Forh., Stockh. 27: 607–776, pls. 7–9. Google Scholar Uhler, P. R., 1895, An ...
Tópico(s): Banana Cultivation and Research
1952 - Royal Entomological Society | Transactions of the Royal Entomological Society of London
... buds of Quercus. Bot. Gas. 84, 187–199, pls. 7–9. 10.1086/333776 Google Scholar Leendertz, Jani ... und Zweck der Stipeln. Linnaea, 17, 193–234, pls. 7–8. Google Scholar Reinke, J. (1897). “Untersuchungen über ...
Tópico(s): Plant and animal studies
1928 - Wiley | Biological reviews/Biological reviews of the Cambridge Philosophical Society
... Austin, 1954. vii + 582 pp., 7 figs., 134 pls. $7.50. - Volume 22 Issue 3
Tópico(s): Botany, Ecology, and Taxonomy Studies
1957 - Cambridge University Press | American Antiquity
John L. Paradiso, George Gilbert. Goodwin, Arthur M. Greenhall,
... Art. 3, pp. 187-302, fig. 1-113, pl. 7–46. 26 June 1961. Price, $4.00. Get ... Art. 3, pp. 187–302, fig. 1–113, pl. 7–46. 26 June 1961. Price, $4.00. John ...
Tópico(s): Rabies epidemiology and control
1961 - Oxford University Press | Journal of Mammalogy
Gerald E. Coe, G. J. Hogaboam,
... Sugarbeet Parental Line SP 6322-01 (Reg. No. PL 7) Gerald E. Coe, Gerald E. CoeSearch for more ...
Tópico(s): Sugarcane Cultivation and Processing
1971 - Wiley | Crop Science