Pablo Contreras-Puertas, Manuel Benítez, Amelia Jiménez‐Heffernan, Angel Rebollo-Aguirre, Sonia Cruz-Muñoz,
CONTRERAS-PUERTAS, PABLO M.D.*; BENÍTEZ-SÁNCHEZ, MANUEL M.D.†; JIMÉNEZ-HEFFERNAN, AMELIA M.D.*; REBOLLO-AGUIRRE, ANGEL M. ...
Tópico(s): Central Venous Catheters and Hemodialysis
2002 - Lippincott Williams & Wilkins | Clinical Nuclear Medicine
Belén Gutiérrez‐Gutiérrez, María Dolores del Toro, Alberto M. Borobia, Antonio J. Carcas, Inmaculada Jarrín, María Yllescas, Pablo Ryan, Jerónimo Pachón, Jordi Carratalà, Juan Berenguer, José Ramón Arribas, Jesús Rodríguez‐Baño, Esther Aznar Muñoz, Pedro Gil Divasson, Patricia González Muñiz, Clara Aguirre, Pilar Retamar, Adoración Valiente, Luis Eduardo López-Cortés, Jesús Sojo-Dorado, José María Bravo-Ferrer, Elena Salamanca, Zaira R. Palacios‐Baena, Patricia Pérez‐Palacios, M. Gandullo-Moro, Rocío Ruíz-Hueso, Natalia Moya-González, Agustín Valido-Morales, María Pavón-Masa, Marta Díaz‐Menéndez, Fernando Calle, Marta Arsuaga Vicente, Elena Trigo Esteban, Rosa de Miguel Buckley, Julen Cadiñanos, Carmen Busca, Rafael Micán, Marta Mora-Rillo, Belén Loeches Yagüe, José Ignacio Bernardino, Julio García‐Rodríguez, Rocío Montejano, Beatriz Díaz‐Pollán, Juan Carlos López, Margarita Ramírez-Schacke, Isabel Gutiérrez, Francisco Tejerina, Teresa Aldámiz‐Echevarría, Cristina Díez, Chiara Fanciulli, Leire Pérez‐Latorre, F Parras, Pilar Catalán, María E. García-Leoni, Isabel Pérez-Tamayo, Luís Puente‐Maestu, Jamil Cedeño, A. Such-Díaz, Elena Alba Álvaro-Alonso, Elsa Izquierdo-García, Juan Torres‐Macho, Guillermo Cuevas, Helena Notario, B. Mestre-Gómez, Eva Jiménez, Inés Fernández-Jiménez, Ana Josefa Tebar-Martínez, Fátima Brañas, Jorge Valencia, Mario Pérez, Marta Alvarado, Gabriela Abelenda-Alonso, Carmen Ardanuy, Alba Bergas, Guillermo Cuervo, M.A. Domı́nguez, Miguel Fernández-Huerta, Carlota Gudiol, Laia Lorenzo-Esteller, Jordí Niubó, Sandra Pérez‐Recio, Daniel Podzamczer, Miquel Pujol, Alexander Rombauts, Núria Trullen, José Miguel Cisneros, Cristina Amodeo, Pedro Camacho, Núria Espinosa, Manuel García‐Gutiérrez, Luis Jara‐Palomares, Rocío González-León, José Molina, Maria Martin, María Paniagua, Manuel Poyato Borrego, Ángel Rodríguez-Villodres, Zaida Ruiz de Azua, Celia Salamanca, Mo Antonia Sepúlveda Berrocal, Carmen Busca, Pilar Toledano Sierra, Verónica Cano Llorente, Sadaf Zafar Iqubal-Mirza, Gema Muñiz, Inmaculada Martín Pérez, Helena Mozas Moriñigo, Ana Alguacil, María Paz García Butenegro, Ana Isabel Peláez Ballesta, Elena Morcillo Rodríguez, Josune Goikoetxea, María José Blanco Vidal, Javier Nieto Arana, Mikel Del Álamo Martínez de Lagos, Isabel Hernández, Inés Pérez Zapata, Rafael Silvariño Fernández, Jon Ugalde Espiñeira, María Rivas-Carmenado, Lucía Suárez Pérez, Silvia Suárez Diaz, Carmen Yllera Gutiérrez, Vicente Boix, Marcos Díez Martínez, Melissa Carreres Candela, Cristina Gómez‐Ayerbe, Javier Sánchez-Lora, José Luis Velasco Garrido, María López-Jodar, Jesús Santos González, Jesús Ruiz Aragón, Ianire Virto Peña, Vanessa Castro, Diana Sande Llovo, Sonia Vega Molpeceres, Estel Pons Viñas, Oscar del Río Pérez, Silvia Valero Rovira, Judit Villar-García, Joan Gómez‐Junyent, María Cecilia Cánepa, Silvia Castañeda Espinosa, Emílio Letang, Mar Arenas-Miras, Sílvia Gómez-Zorrilla, Francesca Sánchez, Elisabet Lerma-Chippirraz, Elisa García Vázquez, Encarnación Moral Escudero, Aychel Elena Roura Piloto, Esther García Almodóvar, Carmen Sáez Barberá, Zineb Karroud, José Hernández‐Quero, David Vinuesa García, José Luis García Fogeda, José Antonio Peregrina, María Novella Mena, Cristina Hernández Gutiérrez, José Sanz Moreno, Ramón Pérez‐Tanoira, Jorge Navarro, Javier Balsa Vázquez, Aida Gutiérrez-García, Alberto Arranz Caso, Juan Cuadros‐González, Melchor Álvarez‐Mon, Vicente Ferrer Díaz de Brito Fernández, Raimón Sanmartí, Aina Gabarrell‐Pascuet, Daniel Molina Morant, Sergio España Cueto, Jonathan Cámara Fernández, Albert Sabater Gil, Laura López, Ruth Jorge García, Nora Molina Torres, M Sempere, Francisco Javier De Castro Vega, Ignacio de los Santos, Lucio García‐Fraile, Miguel Sampedro Núñez, Ana Barrios Blandino, Carlos Rodríguez Franco, Daniel Useros Brañas, Almudena Villa Martí, Javier Oliver Ortega, Alexia Costanza Espiño Álvarez, Jesús Sanz, María Rexach Fumaña, Guillem Policarpo Torres, Meritxell Ortega Montoliu, Clara Sala Jofre, Susana Casas Rodríguez, Cecilia Tortajada Alamilla, Carmina Oltra, Mar Masiá, Félix Gutiérrez Rodero, María Rosa Oltra Sempere, Sara Vela Berna, Miguel Pedromingo Kus, María Ángeles Garcinuño, Alexandra de la Vega, Sergio Pérez Pinto, Pilar Hernández Machín, Alba Alastrué Violeta, María Carmen Fariñas Álvarez, Claudia González-Rico, Francisco Arnáiz de las Revillas, Jorge Calvo, Mónica Gozalo, Francisco Mora Gómez, Ana Milagro, Miriam Latorre-Millán, Antonio Rezusta López, Ana Martínez Sapiñá, Yolanda Meije, Alba Ribera, Lucía Ortega Enciso, Xavier Salvador, Juan Emilio Losa García, María Velasco, María Teresa Pérez-Rodríguez, Alexandre Pérez‐González, Moncef Belhassen‐García, Beatriz Rodríguez-Alonso, Amparo López‐Bernús, Cristina Carbonell, Rafael Torres Perea, Juan Cantón De Seoane, Blanca Sánchez Alonso, Sara Lidia Kamal, Lucía Cajuela, David Roa, Miguel Cervero, Alberto Oreja, Juan Pablo Avilés, Lidia Martín, Iván Pelegrín Senent, Rosana Rouco Esteves Marques, Jorge Parra-Ruiz, Violeta Ramos-Sesma, Jésica Abadía‐Otero, Juan Salillas Hernando, Robert Torres Sánchez del Arco, Miguel Torralba, Alberto Serrano Martínez, Sergio Gilaberte Reyzábal, Marina Pacheco Martínez-Atienza, Mónica Liébana Gómez, Sara Fernández Rodríguez, Álvaro Varela Plaza, Henar Calvo Sánchez, Patricia Martínez, Patricia González‐Ruano, Eduardo Malmierca, Isabel Rábago Lorite, Beatriz Pérez-Monte Mínguez, Ángeles García Flores, Pere Comas Casanova, Merçe Sirisi, Richard Raitt Rodríguez-Rojas, José Luis Díaz de Tuesta del Arco, Ruth Figueroa Cerón, Ander González Sarria, María Remedios Alemán Valls, María Socas, O. Sanz, Karim Mohamed Ramírez, Melchor Riera Jaume, Helem Vílchez, Francesc Albertí, Ana Isabel Cañabate, Víctor J. Moreno Cuerda, Silvia Álvarez Kaelis, Beatriz Álvarez Zapatero, Alejandro García, Elena Isaba Ares, Covadonga Morcate Fernández, Andrea Rodríguez, Lucía Ramos Merino, Laura Castelo, M Mahia, Mónica González Bardanca, Efrén Sánchez Vidal, Enrique Míguez Rey, Ana Correa Ruiz, José Mo García de Lomas Guerrero, Daniel Daniel López, Rebeca Marinas, Marta Morando, Lucía Gómez García, Lucía Boix Palop, Beatriz Dietl Gómez-Luengo, Iris Pedrola Gorrea,
SummaryBackgroundThe clinical presentation of COVID-19 in patients admitted to hospital is heterogeneous. We aimed to determine whether clinical phenotypes of patients with COVID-19 can be derived from clinical data, to assess the reproducibility of these phenotypes and correlation with prognosis, and to derive and validate a simplified probabilistic model for phenotype assignment. Phenotype identification was not primarily intended as a predictive tool for mortality.MethodsIn this study, we used ...
Elsevier BV
Pablo S. Contreras, Pablo Tapía, Lila González-Hódar, Ivana Peluso, Chiara Soldati, Gennaro Napolitano, Maria Matarese, Macarena Las Heras, Cristian Valls, Alexis Martínez, Elisa Balboa, Juan Francisco Castro, Nancy Leal, Frances M. Platt, Andrzej Sobota, Dominic Winter, Andrés D. Klein, Diego L. Medina, Andrea Ballabio, Alejandra Álvarez, Silvana Zanlungo,
The transcription factor EB (TFEB) has emerged as a master regulator of lysosomal biogenesis, exocytosis, and autophagy, promoting the clearance of substrates stored in cells. c-Abl is a tyrosine kinase that participates in cellular signaling in physiological and pathophysiological conditions. In this study, we explored the connection between c-Abl and TFEB. Here, we show that under pharmacological and genetic c-Abl inhibition, TFEB translocates into the nucleus promoting the expression of its target ...
Tópico(s): Cellular transport and secretion
2020 - Cell Press | iScience
Juan Berenguer, Pablo Ryan, Jesús Rodríguez‐Baño, Inmaculada Jarrín, Jordi Carratalà, Jerónimo Pachón, María Yllescas, José Ramón Arriba, Esther Aznar Muñoz, Pedro Gil Divasson, Patricia González Muñiz, Clara Aguirre, Juan Carlos López, Margarita Ramírez-Schacke, Isabel Gutiérrez, Francisco Tejerina, Teresa Aldámiz‐Echevarría, Cristina Díez, Chiara Fanciulli, Leire Pérez‐Latorre, F Parras, Pilar Catalán, María E. García-Leoni, Isabel Pérez-Tamayo, Luís Puente‐Maestu, Jamil Cedeño, Juan Berenguer, Marta Díaz‐Menéndez, Fernando Calle, Marta Arsuaga Vicente, Elena Trigo Esteban, Ma del Mar Lago Núñez, Rosa de Miguel Buckley, Julen Cadiñanos, Carmen Busca, Alfredo Mican, Marta Mora-Rillo, Juan Carlos Ramos Ramos, Belén Loeches Yagüe, José Ignacio Bernardino, Julio García‐Rodríguez, José Ramón Arribas, Ana Such Díaz, Elena Álvaro Alonso, Elsa Izquierdo-García, Juan Torres Macho, Guillermo Cuevas, Jesús Troya, Beatriz Mestre Gómez, Eva Jiménez, Inés Fernández Jiménez, A. J. Martinez, Fátima Brañas Baztán, Jorge Valencia de la Rosa, Mario Pérez, Marta Alvarado, Pablo Ryan, Ma Antonia Sepúlveda Berrocal, Carmen Busca, Pilar Toledano Sierra, Verónica Cano Llorente, Sadaf Zafar Iqubal-Mirza, Gema Muñiz, Inmaculada Martín Pérez, Helena Mozas Moriñigo, Ana Alguacil, María Paz García Butenegro, Ana Isabel Peláez Ballesta, Elena Morcillo Rodríguez, Josune Goikoetxea, María José Blanco Vidal, Javier Nieto Arana, Mikel Del Álamo Martínez de Lagos, Isabel Hernández, Inés Pérez Zapata, Rafael Silvariño Fernández, Jon Ugalde Espiñeira, Víctor Asensi, Lucía Suárez Pérez, Silvia Suárez Díaz, Carmen Yllera Gutiérrez, Vicente Boix, Marcos Díez Martínez, Melissa Carreres Candela, Cristina Gómez‐Ayerbe, Javier Sánchez-Lora, José Luis Velasco Garrido, María López-Jodar, Jesús Santos González, Jesús Ruiz Aragón, Ianire Virto Peña, Vanessa Castro, Ruth Brea Aparicio, Sonia Vega Molpeceres, Estel Pons Viñas, Oscar del Río Pérez, Silvia Valero Rovira, Judit Villar-García, Joan Gómez‐Junyent, Hernando Knobel, María Cecilia Cánepa, Silvia Castañeda Espinosa, Luisa Sorlí Redó, Robert Güerri‐Fernández, M. Montero, Juan Pablo Horcajada, Elisa García Vázquez, Encarnación Moral Escudero, Alicia Hernández Torres, Esther García Almodóvar, Carmen Sáez Barberá, Zineb Karroud, José Hernández‐Quero, David Vinuesa García, José Luis García Fogeda, José Antonio Peregrina, María Novella Mena, Cristina Hernández Gutiérrez, José Sanz Moreno, Ramón Pérez‐Tanoira, Rodrigo Sierra Rodríguez, David Alonso, Aida Gutiérrez-García, Alberto Arranz Caso, Juan Cuadros‐González, Melchor Álvarez‐Mon, Vicente Ferrer Díaz de Brito Fernández, Montserrat Sanmartí, Aina Gabarrell‐Pascuet, Daniel Molina Morant, Sergio España Cueto, Jonathan Cámara Fernández, Albert Sabater Gil, Laura López, Paula Sáez Escolano, Esperanza Bejarano Tello, M Sempere, Salvador Álvarez Martin, Ignacio de los Santos, Lucio García‐Fraile, Miguel Sampedro Núñez, Ana Barrios Blandino, Carlos Rodríguez Franco, Daniel Useros Brañas, Almudena Villa Martí, Javier Oliver Ortega, Alexia Costanza Espiño Álvarez, Jesús Sanz, María Rexach Fumaña, Ivette Abascal Cambras, Ana del Cielo Pérez Jaén, Clara Sala Jofre, Susana Casas Rodríguez, Cecilia Tortajada Alamilla, Carmina Oltra, Mar Masiá, Félix Gutiérrez Rodero, Ana Ferrer Ribera, Carlos Bea Serrano, Miguel Pedromingo Kus, María Ángeles Garcinuño, Silvana Fiorante, Sergio Pérez Pinto, Pilar Hernández Machín, Alba Alastrué Violeta, María Carmen Fariñas Álvarez, Claudia González-Rico, Francisco Arnáiz de las Revillas, Jorge Calvo, Mónica Gozalo, Francisco Mora Gómez, Ana Milagro, Miriam Latorre-Millán, Antonio Rezusta López, Ana Martínez Sapiñá, Yolanda Meije, Alejandra Duarte Borges, Júlia Pareja Coca, Mercedes Clemente Presas, Juan Emilio Losa García, Ana Vegas Serrano, María Teresa Pérez-Rodríguez, Alexandre Pérez‐González, Moncef Belhassen‐García, Beatriz Rodríguez-Alonso, Amparo López‐Bernús, Cristina Carbonell, Rafael Torres Perea, Juan Cantón de Seoane, Blanca Sánchez Alonso, Sara Lidia Kamal, Lucía Cajuela, David Roa, Miguel Cervero, Alberto Oreja, Juan Pablo Avilés, Lidia Martín, Iván Pelegrín Senent, Rosana Rouco Esteves Marques, Jorge Parra-Ruiz, Violeta Ramos-Sesma, Jessica Abadia Otero, Juan Salillas Hernando, Robert Torres Sánchez del Arco, Miguel Torralba, Alberto Serrano Martínez, Sergio Gilaberte Reyzábal, Marina Pacheco Martínez-Atienza, Mónica Liébana Gómez, Sara Fernández Rodríguez, Álvaro Varela Plaza, Henar Calvo Sánchez, Patricia Martínez, Patricia González‐Ruano, Eduardo Malmierca, Isabel Rábago Lorite, Beatriz Pérez-Monte Mínguez, Ángeles García Flores, Pere Comas Casanova, Merçe Sirisi, Richard Raitt Rodríguez-Rojas, José Luis Díaz de Tuesta del Arco, Ruth Figueroa Cerón, Ander González Sarria, María Remedios Alemán Valls, María Socas, O. Sanz, Karim Mohamed Ramírez, Melchor Riera Jaume, Helem Vílchez, Francesc Albertí, Ana Isabel Cañabate, Víctor J. Moreno Cuerda, Silvia Álvarez Kaelis, Beatriz Álvarez Zapatero, Alejandro García, Elena Isaba Ares, Covadonga Morcate Fernández, Andrea Rodríguez, Lucía Ramos Merino, Laura Castelo, M Mahia, Mónica González Bardanca, Efrén Sánchez Vidal, Enrique Míguez Rey, Javier de la Torre, José María García de Lomas Guerrero, Elena Morte, Silvia Loscos, Ana M. Camon, Lucía Gómez García, Lucía Boix Palop, Beatriz Dietl Gómez-Luengo, Iris Pedrola Gorrea, Amparo Blasco Claramunt, Cristina López Mestanza, Esther Fraile Villarejo, Tomás Tosco Núñez, María Aroca Ferri, José Tomás Algado Rabasa, Ana María Garijo Saiz, Concepción Amador Prous, Jesús Rodríguez‐Baño, Pilar Retamar, Adoración Valiente, Luis Eduardo López-Cortés, Jesús Fernández‐Sojo, Belén Gutiérrez‐Gutiérrez, José María Bravo-Ferrer, Elena Salamanca, Zaira Palacios, Patricia Pérez‐Palacios, Enrique Peral, Jose Antonio Pérez de León, Jesús Sánchez-Gómez, Lucía Marín-Barrera, Domingo García-Jiménez, Jordi Carratalà, Gabriela Abelenda-Alonso, Carmen Ardanuy, Alba Bergas, Guillermo Cuervo, M.A. Domı́nguez, Miguel Fernández-Huerta, Carlota Gudiol, Laia Lorenzo-Esteller, Jordí Niubó, Sandra Pérez‐Recio, Daniel Podzamczer, Miquel Pujol, Alexander Rombauts, Núria Trullen, Miguel Salavert, Iván Castro Hernández, Adriana Hernández Belmonte, Raquel Martínez Goñi,
ObjectivesTo analyse the characteristics and predictors of death in hospitalized patients with coronavirus disease 2019 (COVID-19) in Spain.MethodsA retrospective observational study was performed of the first consecutive patients hospitalized with COVID-19 confirmed by real-time PCR assay in 127 Spanish centres until 17 March 2020. The follow-up censoring date was 17 April 2020. We collected demographic, clinical, laboratory, treatment and complications data. The primary endpoint was all-cause mortality. ...
Elsevier BV
Pedro Cuesta Valiño, Pablo Gutiérrez Rodríguez, Pablo Contreras-Contreras,
La búsqueda de la felicidad es la explicación más general del comportamiento humano. A lo largo de los años se ha intentado establecer enfoques de medición que faciliten su análisis. Un primer paso es la necesidad de entender el bienestar de las personas a través de la idea de “sentirse mejor” que ha llevado a la medición de la salud subjetiva y no sólo biológica. Este artículo pretende comprender mejor los orígenes del concepto de felicidad del consumidor, sus enfoques y las escalas de medición. ...
Tópico(s): Logistics and Transportation Systems
2023 - Editorial Universidad de Sevilla | Anduli
Produção Nacional
Revisado por pares
Valentina Fritz, Gonzalo Tereucán, Christian Santander, Boris Contreras, Pablo Cornejo, Paulo Ademar Avelar Ferreira, Antonieta Ruíz,
In potato (Solanum tuberosum) crops, the use of fungicides to control some diseases is widespread; however, it has been reported that this practice can modify the potato polyphenolic content, and new strategies oriented to the potato defense system are necessary. One alternative is the use of arbuscular mycorrhizal fungi (AMF) to improve the defense mechanisms of plants. In this study, phenolic profiles and antioxidant activities in leaves of three potato genotypes (CB2011-509, CB2011-104, and VR808) ...
Tópico(s): Fungal Biology and Applications
2022 - Multidisciplinary Digital Publishing Institute | Plants
Gerardo Zapata-Sifuentes, Luis Guillermo Hernández-Montiel, Jorge Sáenz‐Mata, Manuel Fortis-Hernández, Eduardo Blanco-Contreras, Roberto Gregorio Chiquito-Contreras, Pablo Preciado-Rangel,
Cucumber fruit is rich in fiber, carbohydrates, protein, magnesium, iron, vitamin B, vitamin C, flavonoids, phenolic compounds, and antioxidants. Agrochemical-based production of cucumber has tripled yields; however, excessive synthetic fertilization has caused problems in the accumulation of salts in the soil and has increased production costs. The objective of this study was to evaluate the effect of three strains of plant growth-promoting rhizobacteria (PGPR) on cucumber fruit growth and quality ...
Tópico(s): Nematode management and characterization studies
2022 - Multidisciplinary Digital Publishing Institute | Plants
Alonso Bucarey, Dante Contreras, Pablo Muñoz,
We study the labor market returns to a state-guaranteed loan used to finance university degrees in Chile. Using a regression discontinuity design, we show that marginally eligible students forgo vocational education in favor of university education but reduce their probability of graduation. Even though university loan takers accumulate more student debt, their labor market outcomes are not different from those of ineligible students. We find suggestive evidence that the lower quality of the receiving ...
Tópico(s): School Choice and Performance
2019 - University of Chicago Press | Journal of Labor Economics
Manuel Alonso Dos Santos, Orlando Llanos‐Contreras, Pablo Farías,
Abstract The purpose of this study is to determine whether the image transfer theory and the elaboration likelihood model can provide a theoretical framework capable of assessing the influence of consumers’ product involvement and family firms’ identity communication through websites on consumer responses. This research conducted an experiment using an eye‐tracking technique measuring attention to family and nonfamily corporate websites. The procedure involved 120 participants. Consistent with the ...
Tópico(s): Consumer Behavior in Brand Consumption and Identification
2019 - Wiley | Psychology and Marketing
Katherine Márquez, David Contreras, Pablo Salgado, Claudia Mardones,
Exposure of white wine to oxygen can cause detrimental effects, such as loss of sensorial characteristics. New antecedents, to the oxidation of wine, establish the importance of the formation of metallic complexes with compounds with adjacent hydroxyls. These complexes could reduce iron, promoting the formation of radicals through the Fenton reaction. The formation of hydroxyl radical (OH) induced by air was found in all 18 white wines analysed by electronic paramagnetic resonance (EPR) spectroscopy. ...
Tópico(s): Horticultural and Viticultural Research
2018 - Elsevier BV | Food Chemistry
Antonieta Ruíz, Ariel Aguilera, Stefano Ercoli, José Luis Parada Rodríguez, Peter Winterhalter, Boris Contreras, Pablo Cornejo,
Phenolic composition of potatoes (Solanum tuberosum) with colored flesh has been previously reported, highlighting their anthocyanin composition. However, there is less information available about the profiles and concentrations of hydroxycinnamic acid derivatives (HCADs) in these potatoes. In pigmented potatoes from Southern Chile, three HCADs have been detected, corresponding to the trans isomers of 3-, 4- and 5-caffeoylquinic acid. It is remarkable that after frying, the HCAD concentrations increased ...
Tópico(s): Tea Polyphenols and Effects
2018 - Elsevier BV | Food Chemistry
María Belén Carboneras Contreras, Pablo Cañizares, Manuel A. Rodrigo, José Villaseñor, F.J. Fernández,
In this work, a combination of electrochemical and biological technologies is proposed to remove clopyralid from Soil Washing Effluents (SWE). Firstly, soil washing was carried out to extract clopyralid from soil. After that, four different anodes-Ir-MMO, Ru-MMO, pSi-BDD and Carbon Felt (CF)-were evaluated in order to increase the biodegradability of the SWE. CF was selected because was the only one able to transform the pesticide to a more biodegradable compounds without completely mineralizing it. ...
Tópico(s): Microbial Fuel Cells and Bioremediation
2017 - Elsevier BV | Bioresource Technology
Manuel Sánchez‐Moreno, Fernando Gómez-Contreras, Pablo Navarro, Clotilde Marı́n, Inmaculada Ramírez-Macías, M.J. Rosales, Lucrecia Campayo, Carolina Cano, Ana María Sanz, María J. R. Yunta,
The in vitro leishmanicidal activity of a series of imidazole-containing phthalazine derivatives 1-4 was tested on Leishmania infantum, Leishmania braziliensis and Leishmania donovani parasites, and their cytotoxicity on J774·2 macrophage cells was also measured. All compounds tested showed selectivity indexes higher than that of the reference drug glucantime for the three Leishmania species, and the less bulky monoalkylamino substituted derivatives 2 and 4 were clearly more effective than their ...
Tópico(s): Synthesis and Biological Evaluation
2015 - Cambridge University Press | Parasitology
Julián Brañes, Héctor R. Contreras, Pablo Cabello, Vlado Antonic, Leonardo Guiloff, Manuel Brañes,
Background Application of extracorporeal shockwave therapy (ESWT) induces an improvement in tissue healing associated with augmented tissue perfusion. The present study aimed to investigate the responses of human rotator cuff tissue to the application of ESWT. Methods Thirty-one consecutive patients with symptomatic rotator cuff tendinopathy with complete tears were approached and enrolled in the present study. Before surgical resolution, a single treatment of focused ESWT was offered to all patients. ...
Tópico(s): Myofascial pain diagnosis and treatment
2012 - SAGE Publishing | Shoulder & Elbow
Marcela Franco, Carolina Contreras, Pablo A. Cortés, Mark A. Chappell, Mauricio Soto‐Gamboa, Roberto F. Nespolo,
During periods of cold, small endotherms depend on a continuous supply of food and energy to maintain euthermic body temperature (T(b)), which can be challenging if food is limited. In these conditions, energy-saving strategies are critical to reduce the energetic requirements for survival. Mammals from temperate regions show a wide arrange of such strategies, including torpor and huddling. Here we provide a quantitative description of thermoregulatory capacities and energy-saving strategies in Dromiciops ...
Tópico(s): Evolution and Paleontology Studies
2012 - The Company of Biologists | Biology Open
Marco Contreras, Pablo Billeke, Sergio Vicencio, Carlos Madrid, Guetón Perdomo, Marcela González, Fernando Torrealba,
Drug craving critically depends on the function of the interoceptive insular cortex, and may be triggered by contextual cues. However, the role of the insula in the long-term memory linking context with drug craving remains unknown. Such a memory trace probably resides in some neocortical region, much like other declarative memories. Studies in humans and rats suggest that the insula may include such a region. Rats chronically implanted with bilateral injection cannulae into the high-order rostral ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2012 - Springer Nature | Neuropsychopharmacology
Mauricio Canals, Daniela Figueroa, C. Alfaro, Tatiana Hideko Kawamoto, Hugo Torres‐Contreras, Pablo Sabat, Claudio Veloso,
The metabolic and water evaporation strategies in spiders may be part of a set of physiological adaptations to tolerate low or unpredictable food availability, buffering spiders against environmental fluctuations such as those of the high mountains of the central Andes. The aim of this study is to analyze experimentally the variations in metabolic rate and the rate of evaporative water with food and/or water restriction in a high mountain mygalomorph spider population (Paraphysa sp.). We found that ...
Tópico(s): Animal Behavior and Reproduction
2011 - Elsevier BV | Journal of Insect Physiology
José Octavio, Jesús Ruíz-Contreras, Pablo Amair, Bernardo Octavio, Domenico Fabiano, Federico Moleiro, Stefano Omboni, Antonella Groppelli, Grzegorz Bilo, Giuseppe Mancia, Gianfranco Parati,
Background Conventional calculation of mean 24-h ambulatory blood pressure (BP), SBP and DBP based on the average of all BP readings disregards the fact that a larger number of measurements is usually scheduled during the daytime than at night, an imbalance possibly leading to an overestimation of 24-h average BP. The aim of our study was to quantify this possible bias and to explore its determinants. Methods Four hundred and fifty untreated individuals were subdivided into three groups (150 individuals ...
Tópico(s): Cardiovascular Syncope and Autonomic Disorders
2010 - Lippincott Williams & Wilkins | Journal of Hypertension
Ángel Castro-Vázquez, Irene Espinosa-Gutiérrez, Patricia Rodríguez-Contreras, Pablo Santos‐Iglesias,
As the interest on the factors related to the perception of health is growing, the present ex post facto study analyzes the relationship between the self-perception of health and different indicators which can influence it. The relationship between the
Tópico(s): Health disparities and outcomes
2007 - Elsevier BV | International Journal of Clinical and Health Psychology
Paulina Bravo M., Gerardo Weisstaub, Paulina Balboa, Claudia Torrejón, Rodrigo Bozzo, María Lina Boza, Ilse Contreras, Pablo Jorquera, Luis Astorga, Gerardo Weisstaub,
cystic fibrosis (CF) is the most common inherited disease in Caucasian population. Nowadays, long survival has led to the emergence of new complications, such as CF bone disease (CFBD), which is characterized by increased fracture risk.evaluate the association of bone mineral density (BMD) with lung function and BMD with 25-hydroxivitamin D (25OHD) plasmatic levels in children/adolescents with CF.we conducted a multicenter, cross-sectional study with clinically stable CF patients between five and 18 ...
Tópico(s): Child Nutrition and Water Access
2018 - Arán Ediciones | Nutrición Hospitalaria
Raúl Vivar, Renatto Anfossi, Claudio Humeres, Mabel Catalán, Christopher Reyes, S Juan Pablo Cárdenas, Alejandra Contreras, Pablo Aránguiz, F. Jesus Gonzalez, Guillermo Díaz‐Araya,
In the normal heart, cardiac fibroblasts (CFs) maintain extracellular matrix (ECM) homeostasis, whereas in pathological conditions, such as diabetes mellitus (DM), CFs converse into cardiac myofibroblasts (CMFs) and this CFs phenoconversion increase the synthesis and secretion of ECM proteins, promoting cardiac fibrosis and heart dysfunction. High glucose (HG) conditions increase TGF-β1 expression and FoxO1 activity, whereas FoxO1 is crucial to CFs phenoconversion induced by TGF-β1. In addition, FoxO1 ...
Tópico(s): Connective Tissue Growth Factor Research
2021 - Elsevier BV | Cellular Signalling
... For a more extensive discussion of this process, Pablo Contreras and Domingo Lovera, 'A Constitued Constituent Process? Chile' ... Constitutional Awakening' (2020) 31 Law and Critique 7; Pablo Contreras and Lovera (n 51). However, this 'revolutionary narrative' ...
Tópico(s): Judicial and Constitutional Studies
2023 - Taylor & Francis | King s Law Journal
Pablo A. Gutiérrez, Sebastián E. Godoy, Sergio Torres, Patricio Oyarzún, Ignacio Sanhueza, Víctor Díaz-García, Braulio Contreras-Trigo, Pablo Coelho,
In this article we present the development of a biosensor system that integrates nanotechnology, optomechanics and a spectral detection algorithm for sensitive quantification of antibiotic residues in raw milk of cow. Firstly, nanobiosensors were designed and synthesized by chemically bonding gold nanoparticles (AuNPs) with aptamer bioreceptors highly selective for four widely used antibiotics in the field of veterinary medicine, namely, Kanamycin, Ampicillin, Oxytetracycline and Sulfadimethoxine. ...
Tópico(s): Microbial infections and disease research
2020 - Multidisciplinary Digital Publishing Institute | Sensors
Margit Schraders, Stefan A. Haas, N.J.D. Weegerink, Jaap Oostrik, Hao Hu, Lies H. Hoefsloot, Sriram Kannan, P.L.M. Huygen, Ronald J. E. Pennings, R.J.C. Admiraal, Vera M. Kalscheuer, Henricus P. M. Kunst, Hannie Kremer,
... G. Avendano C. Fernandez-Moreno C. Villar A. Contreras J. de Pablo F. Pichel J.G. Varela-Nieto I. Delayed inner ear maturation and neuronal loss in postnatal Igf-1-deficient mice.J. Neurosci. 2001; 21: 7630-7641PubMed Google Scholar, 29Camarero G. Villar M.A. Contreras J. Fernández-Moreno C. Pichel J.G. Avendaño ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2011 - Elsevier BV | The American Journal of Human Genetics
Stefano Ercoli, José Luis Parada Rodríguez, Luís Bustamante, Isidro Hermosín‐Gutiérrez, Boris Contreras, Pablo Cornejo, Antonieta Ruíz,
The effect of cooking on the concentrations of phenolic compounds and antioxidant activities in 33 colored-fleshed potatoes genotypes was evaluated. The phenolic profiles, concentrations, and antioxidant activity were evaluated with a liquid chromatography diode array detector coupled to a mass spectrometer with an electrospray ionization interface (HPLC-DAD-ESI-MS/MS). Eleven anthocyanins were detected; in the case of red-fleshed genotypes, these were mainly acyl-glycosides derivatives of pelargonidin, ...
Tópico(s): Plant Pathogens and Resistance
2021 - Multidisciplinary Digital Publishing Institute | Molecules
F. G. CONTRERAS, Pablo Navarro,
Abstract Addition reactions in acidic media have been performed on the oxirane ring of unsubstituted, 2‐methyl‐ and 2,3‐dimethyl‐ substituted 2,3‐epoxy‐4a,12a‐diaza‐1,2,3,4,4a,5,12,12a‐octahydronaphthacene‐5,12‐diones. These reactions proceed in a stereospecific way; the Furst‐Plattner rule of 1,2‐ trans ‐diaxial ring‐opening is obeyed as can be deduced from the nmr stereochemical study on the terminal piperidazine‐ring moiety of the addition products. Acylation shift effects and 1,3‐ syn ‐diaxial ...
Tópico(s): Organic Chemistry Cycloaddition Reactions
1979 - Wiley | Journal of Heterocyclic Chemistry
Pablo Contreras Kallens, Ross Deans Kristensen‐McLachlan, Morten H. Christiansen,
Abstract To what degree can language be acquired from linguistic input alone? This question has vexed scholars for millennia and is still a major focus of debate in the cognitive science of language. The complexity of human language has hampered progress because studies of language–especially those involving computational modeling–have only been able to deal with small fragments of our linguistic skills. We suggest that the most recent generation of Large Language Models (LLMs) might finally provide ...
Tópico(s): Topic Modeling
2023 - Wiley | Cognitive Science
Matthias Boeykens, Etienne Xavier Keller, Andrea Bosio, Oliver Wiseman, Pablo Contreras, Eugenio Ventimiglia, Michele Talso, Amelia Pietropaolo, Thomas Tailly, Vincent De Coninck,
Ureteral stents are essential implants that are used on a daily basis. Since their invention, advances in stent design have been directed towards alleviating stent-related symptoms. It remains unclear how the material composition of the stent affects stent-related symptoms.
Tópico(s): Renal and Vascular Pathologies
2022 - Elsevier BV | European Urology Open Science
Adam Nunn, Isaac Rodríguez‐Arévalo, Zenith Tandukar, Katherine Frels, Adrián Contreras‐Garrido, Pablo Carbonell‐Bejerano, Panpan Zhang, Daniela Ramos Cruz, Katharina Jandrasits, Christa Lanz, Anthony Brusa, Marie Mirouze, Kevin Dorn, David W. Galbraith, Brice A. Jarvis, John C. Sedbrook, Donald L. Wyse, Christian Otto, David Langenberger, Peter F. Stadler, Detlef Weigel, M. David Marks, James A. Anderson, Claude Becker, Ratan Chopra,
Summary Thlaspi arvense (field pennycress) is being domesticated as a winter annual oilseed crop capable of improving ecosystems and intensifying agricultural productivity without increasing land use. It is a selfing diploid with a short life cycle and is amenable to genetic manipulations, making it an accessible field‐based model species for genetics and epigenetics. The availability of a high‐quality reference genome is vital for understanding pennycress physiology and for clarifying its evolutionary ...
Tópico(s): Genetic diversity and population structure
2022 - Wiley | Plant Biotechnology Journal
Pablo Contreras Kallens, Morten H. Christiansen,
Traditional accounts of language postulate two basic components: words stored in a lexicon, and rules that govern how they can be combined into meaningful sentences, a grammar. But, although this words-and-rules framework has proven itself to be useful in natural language processing and cognitive science, it has also shown important shortcomings when faced with actual language use. In this article, we review evidence from language acquisition, sentence processing, and computational modeling that ...
Tópico(s): Syntax, Semantics, Linguistic Variation
2022 - Frontiers Media | Frontiers in Artificial Intelligence