Catherine Hoofd, Steven J.T. Huang, Samuel Gusscott, Sonya H.L. Lam, Rachel Wong, A.J.B. Johnston, Susana Ben‐Neriah, Christian Steidl, David W. Scott, Hélène Bruyère, Tanya L. Gillan, Cynthia L. Toze, Alina S. Gerrie, Andrew P. Weng,
... Famà R. De Paoli L. Bulian P. Gattei V. Guarini A. Deaglio S. Capello D. Rabadan R. Pasqualucci L. Dalla-Favera R. Foà R. Gaidano G. Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia.Blood. 2012; 119: 521-529Crossref PubMed Scopus (369) Google Scholar, 21Sportoletti P. Baldoni S. Cavalli L. Del Papa B. Bonifacio E. Ciurnelli R. Bell A.S. Di Tommaso ...
Tópico(s): Lymphoma Diagnosis and Treatment
2020 - Elsevier BV | Journal of Molecular Diagnostics
Laura Ramaciotti, Sabrina Landini,
... Italia: venne fondata nel 1391 dal marchese Alberto V d’Este, su concessione di Papa Bonifacio IX. I primi insegnamenti attivati furono quelli di ...
Tópico(s): Italian Fascism and Post-war Society
2012 - | SxI Springer per l'Innovazione
... dei seguaci degli homoios. Nella prima metà del V secolo a Roma, il papa Innocente I, Bonifacio I e Celestino I chiudono le chiese dei ...
Tópico(s): Byzantine Studies and History
2010 - John Paul II Catholic University of Lublin | Vox Patrum
Produção Nacional
Revisado por pares
... monarcas em franca ascensão (caso da disputa entre Bonifácio VIII e Filipe IV, da França). Além disso, as novas soluções configuravam-se antes como favoráveis aos poderes civis que à autoridade papal. Um aspecto significativo da ampliação do poder e prestígio das monarquias foi a própria transferência do papado para a cidade francesa de Avinhão, a partir de 1309, sob o papa Clemente V. O referido pontífice atendia à expectativa do mesmo ...
Tópico(s): Historical Education and Society
2008 - UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO | História (São Paulo)
... suo soggiorno in Italia, Raimondo Lullo indirizza a papa Celestino V una lettera (dagli studiosi collocata nel novembre del 1294), della quale rimane la versione originale catalana, testimoniata da un unico manoscritto; i testimoni della traduzione latina che ci rimangono –due dei quali legati sicuramente ad ambiente autoriale– sono tutti invece indirizzati al successore Bonifacio VIII. La breve durata del pontificato di Celestino ...
Tópico(s): Libraries, Manuscripts, and Books
2019 - | Studia lulliana
Paolo Sportoletti, Stefano Baldoni, Laura Cavalli, Beatrice Del Papa, Ezio Bonifacio, Raffaella Ciurnelli, Alain Sylvin Bell, Ambra Di Tommaso, Emanuela Rosati, Barbara Crescenzi, Cristina Mecucci, Isabella Screpanti, P Marconi, Maria Paola Martelli, Mauro Di Ianni, Franca Falzetti,
B-cell chronic lymphocytic leukaemia (B-CLL) is a heterogeneous disease with a highly variable clinical course (Chiorazzi et al, 2005) and several factors at diagnosis predict prognosis and help guide treatment decisions (Seiler et al, 2006). Unmutated immunoglobulin heavy variable (IGHV) genes and high expression of zeta-chain-associated protein kinase 70 (ZAP-70) are well-known factors for poor prognosis (Rassenti et al, 2004). When they are discordant other cytogenetic and molecular biological factors ...
Tópico(s): Lymphoma Diagnosis and Treatment
2010 - Wiley | British Journal of Haematology
Paolo Sportoletti, Beatrice Del Papa, Mariangela De Ioanni, Lorenzo Moretti, Ezio Bonifacio, Vania Lanterna, Alain Sylvin Bell, Katia Fettucciari, E. Carnevali, Tiziana Zei, Franca Falzetti, Maria Paola Martelli, Antonio Tabilio, Mauro Di Ianni,
T-cell homeostasis is regulated by several molecules; among these, interleukin (IL)-7 plays an essential role in the survival and homeostatic proliferation of peripheral naive T cells. In a previous study, we investigated whether human mesenchymal stromal cells (MSCs) could be engineered with the IL-7 gene to produce functional level of this cytokine. In the present study, we analyzed the impact of different quantities of IL-7 produced by MSCs on the survival and proliferation of a negative immunoselected ...
Tópico(s): Immune Cell Function and Interaction
2006 - Elsevier BV | Biology of Blood and Marrow Transplantation
Mauro Di Ianni, Beatrice Del Papa, Lorenzo Moretti, Simonetta Piattoni, Debora Cecchini, Ezio Bonifacio, Franca Falzetti, Antonio Tabilio,
Abstract We previously demonstrated that when human bone marrow-derived mesenchymal cells (hMSCs) were co-cultured with CD4+/CD25+ T regulatory cells (Tregs) they maintained the T regulatory phenotype and function over time. Here we studied the TGF-beta/Smad signalling and mitogen-activated protein kinase (MAPK) pathways after Tregs/hMSCs co-culture. After 7 days co-culture of highly purified, immuno-selected Tregs and hMSCs from healthy donors, TGF-beta and IL-10 concentrations were dosed and mRNA ...
Tópico(s): Immune cells in cancer
2008 - Elsevier BV | Blood
Eugenia Pittaluga, Graziella Costa, Ewa K. Krasnowska, Roberto Brunelli, Thomas Lundeberg, Maria Grazia Porpora, Daniela Santucci, Tiziana Parasassi,
... PubMed Scopus (82) Google Scholar, 19Di Carlo C. Bonifacio M. Tommaselli G.A. Bifulco G. Guerra G. ... PubMed Scopus (82) Google Scholar, 19Di Carlo C. Bonifacio M. Tommaselli G.A. Bifulco G. Guerra G. ... 20Mannello F. Tonti G.A. Bagnara G.P. Papa S. Role and function of matrix metalloproteinases in ...
Tópico(s): Uterine Myomas and Treatments
2010 - Elsevier BV | Fertility and Sterility
Houriiyah Tegally, James Emmanuel San, Matthew Cotten, Monika Moir, Bryan Tegomoh, Gerald Mboowa, Darren P. Martin, Cheryl Baxter, Arnold W. Lambisia, Amadou Diallo, Daniel G. Amoako, Moussa Moïse Diagne, Abay Sisay, Abdel‐Rahman N. Zekri, Abdou Salam Guèye, Abdoul Karim Sangaré, Abdoul–Salam Ouédraogo, Abdourahmane Sow, Abdualmoniem O. Musa, Abdul Karim Sesay, Abe G. Abias, Adam Elzagheid, Adamou Lagaré, Adedotun-Sulaiman Kemi, Aden Elmi Abar, Adeniji A. Johnson, Adeola Fowotade, Oluwapelumi O. Adeyemi, Adrienne Amuri-Aziza, Agnes Juru, Ahmed Kandeil, Ahmed Mostafa, Ahmed Rebaï, Ahmed Sayed, Kazeem Akano, Aladje Baldé, Alan Christoffels, Alexander J. Trotter, Allan Campbell, Alpha Kabinet Keïta, A. Koné, Amal Bouzid, Amal Souissi, Ambrose Agweyu, Amel Naguib, Ana Victoria Gutiérrez, Anatole Nkeshimana, Andrew J. Page, Anges Yadouléton, Anika Vinzé, Anise N. Happi, Anissa Chouikha, Arash Iranzadeh, Arisha Maharaj, Armel L. Batchi‐Bouyou, Arshad Ismail, Augustina Angelina Sylverken, Augustine Goba, Femi Ayoade, Ayotunde E. Sijuwola, Baba M, Babatunde Lawal Salako, Bamidele Soji Oderinde, Bankole Bolajoko, Bassirou Diarra, Belinda L. Herring, Benjamin Tsofa, Bernard Lekana-Douki, Bernard Mvula, Berthe‐Marie Njanpop‐Lafourcade, Blessing T. Marondera, Bouh Abdi Khaireh, Bouréma Kouriba, Bright Adu, Brigitte Pool, Bronwyn McInnis, Cara E. Brook, Carolyn Williamson, Cassien Nduwimana, Catherine Anscombe, Catherine Pratt, Cathrine Scheepers, Chantal Akoua‐Koffi, Charles N. Agoti, Chastel M. Mapanguy, Cheikh Loucoubar, Chika Onwuamah, Chikwe Ihekweazu, Christian Malaka, Christophe N. Peyrefitte, Chukwa Grace, Chukwuma Ewean Omoruyi, Clotaire Donatien Rafaï, Collins M. Morang’a, Cyril Erameh, Daniel Lule Bugembe, Daniel J. Bridges, Daniel Mukadi‐Bamuleka, Daniel J. Park, David A. Rasmussen, David Baker, D. James Nokes, Deogratius Ssemwanga, Derek Tshiabuila, Dominic S. Y. Amuzu, Dominique Goedhals, Donald S. Grant, Donwilliams O. Omuoyo, Dorcas Maruapula, Dorcas Wanjohi, Ebenezer Foster-Nyarko, Eddy Kinganda-Lusamaki, Edgar Simulundu, Edidah M. Ong’era, Edith N. Ngabana, Edward Okoth Abworo, Edward Otieno, Edwin Shumba, Edwine Barasa, El Bara Ahmed, Elhadi Abdalla Ahmed, Emmanuel Lokilo, Enatha Mukantwari, Eromon Philomena, Essia Belarbi, Etienne Simon‐Lorière, Etilé A. Anoh, Eusébio Manuel, Fabian H. Leendertz, Fahn Taweh, Wasfi Farès, Fatma Abdelmoula, Faustinos Tatenda Takawira, Fawzi Derrar, Fehintola V. Ajogbasile, Florette K. Treurnicht, Onikepe Folarin, Francine Ntoumi, Francisca Muyembe, Frank Edgard Zongo Ragomzingba, Fred Athanasius Dratibi, Fred-Akintunwa Iyanu, Gabriel K. Mbunsu, Gaetän Thilliez, Gemma L. Kay, George O. Akpede, Gert U. van Zyl, Gordon A. Awandare, Grace Kpeli, Grit Schubert, Gugu Maphalala, Hafaliana C. Ranaivoson, Hannah E. Omunakwe, Harris Onywera, Haruka Abe, Héla Karray, Hellen Nansumba, Henda Triki, Herve Albéric Adje Kadjo, Hesham A. Elgahzaly, Hlanai Gumbo, Hota Mathieu, Hugo Kavunga‐Membo, Ibtihel Smeti, Idowu B. Olawoye, Ifedayo Adetifa, Ikponmwosa Odia, Ilhem Boutiba Ben Boubaker, Iluoreh Ahmed Muhammad, Isaac Ssewanyana, Isatta Wurie, Iyaloo Konstantinus, Jacqueline Wemboo Afiwa Halatoko, James Ayei, Janaki Sonoo, Jean-Claude Makangara-Cigolo, Jean‐Jacques Muyembe Tamfum, Jean‐Michel Héraud, Jeffrey G. Shaffer, Jennifer Giandhari, Jennifer Musyoki, Jerome Nkurunziza, Jessica N. Uwanibe, Jinal N. Bhiman, Jiro Yasuda, Joana Morais, Jocelyn Kiconco, John Demby Sandi, John Huddleston, John Kofi Odoom, John Mwita Morobe, John O. Gyapong, John Kayiwa, Johnson Okolie, Joicymara S. Xavier, Jones Gyamfi, Joseph Francis Wamala, Joseph Humphrey Kofi Bonney, Joseph Nyandwi, Josie Everatt, Joweria Nakaseegu, Joyce M. Ngoi, Joyce Namulondo, Judith U. Oguzie, Julia C. Andeko, Julius J. Lutwama, Juma J. H. Mogga, Justin O’Grady, Katherine J. Siddle, Kathleen Victoir, Kayode T. Adeyemi, Kefentse A. Tumedi, Kevin Sanders Da Rosa Carvalho, Khadija Said Mohammed, Koussay Dellagi, Kunda Musonda, Kwabena Obeng Duedu, Lamia Fki‐Berrajah, Lavanya Singh, Lenora Kepler, Leon Biscornet, Leonardo de Oliveira Martins, Lucious Chabuka, Luicer A. Ingasia, Lul Deng Ojok, Lul Lojok Deng, Lynette Isabella Ochola‐Oyier, Lynn Tyers, Madisa Mine, Magalutcheemee Ramuth, Maha Mastouri, Mahmoud ElHefnawi, Maïmouna Mbanne, M.I. Matsheka, Malebogo Kebabonye, Mamadou Diop, Mambu Momoh, Maria da Luz Lima Mendonça, Marietjie Venter, Mariétou F Paye, Martin Faye, Martin M. Nyaga, Mathabo Mareka, Damaris Matoke-Muhia, Maureen W. Mburu, Maxmillian Mpina, Michael Owusu, Michael R. Wiley, Mirabeau Youtchou Tatfeng, Mitoha Ondo’o Ayekaba, Mohamed Abouelhoda, Mohamed Amine Beloufa, Mohamed G. Seadawy, Mohamed K. Khalifa, Mooko Marethabile Matobo, Mouhamed Kane, Mounérou Salou, Mphaphi B. Mbulawa, Mulenga Mwenda, Mushal Allam, My V. T. Phan, Nabil Abid, Nadine Rujeni, Nadir Abuzaid, Nália Ismael, Nancy Elguindy, Ndeye Marième Top, Ndongo Dia, Nédio Mabunda, Marvin Hsiao, Nelson Boricó Silochi, Ngiambudulu M. Francisco, Ngonda Saasa, Nicholas Bbosa, Nickson Murunga, Nicksy Gumede, Nicole Wolter, Nikita Sitharam, Nnaemeka Ndodo, Nnennaya Anthony Ajayi, Noël Tordo, Nokuzola Mbhele, Norosoa Harline Razanajatovo, Nosamiefan Iguosadolo, Nwando Mba, Ojide C. Kingsley, Okogbenin Sylvanus, Femi Oladiji, Moses Olubusuyi Adewumi, Testimony Olumade, Olusola Ogunsanya, Oluwatosin Fakayode, Onwe Emeka Ogah, Ope-Ewe Oludayo, Ousmane Faye, Pamela Smith-Lawrence,
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing in Africa over the past year has led to a major increase in the number of sequences that have been generated and used to track the pandemic on the continent, a number that now exceeds 100,000 genomes. Our results show an increase in the number of African countries that are able to sequence domestically and highlight that local sequencing enables faster turnaround times and more-regular routine surveillance. Despite ...
American Association for the Advancement of Science
Tiziano Barbui, Alessandra Carobbio, Arianna Ghirardi, Alessandra Iurlo, Marta Sobas, Elena Maria Elli, Elisa Rumi, Valerio De Stefano, Francesca Lunghi, Monia Marchetti, Rosa Daffini, Mercedes Gasior Kabat, Beatriz Cuevas, María Laura Fox, Marcio Andrade‐Campos, Francesca Palandri, Paola Guglielmelli, Giulia Benevolo, Claire Harrison, María Ángeles Foncillas, Massimiliano Bonifacio, Alberto Álvarez‐Larrán, Jean‐Jacques Kiladjian, Estefanía Bolaños Calderón, Andrea Patriarca, Keina Quiroz Cervantes, Martin Grießhammer, Valentín García‐Gutiérrez, Alberto Marin Sanchez, Elena Magro Mazo, Giuseppe Carli, Juan Carlos Hernández‐Boluda, Santiago Osorio, Gonzalo Carreño‐Tarragona, Miguel Sagüés Serrano, Rajko Kušec, Begoña Navas Elorza, Anna Angona, Blanca Xicoy Cirici, Emma Lopez Abadia, Steffen Koschmieder, Daniele Cattaneo, Cristina Bucelli, Edyta Cichocka, Anna Kulikowska de Nałęcz, Fabrizio Cavalca, Oscar Borsani, Silvia Betti, Marta Bellini, Natalia Curto‐García, Alessandro Rambaldi, Alessandro M. Vannucchi,
... laboratory of the Foundation for Research (FROM) at Papa Giovanni XXIII Hospital in Bergamo. Continuous variables were ...
Tópico(s): Hemoglobinopathies and Related Disorders
2022 - Wiley | American Journal of Hematology
... Gil (Ávila: Ayuntamiento de Arévalo, 1988). 30 See Bonifacio Porres Alonso, “Los Hospitales Trinitarios de Argel y ...
Tópico(s): Byzantine Studies and History
2011 - Taylor & Francis | Al-Masāq
Paolo Sportoletti, Beatrice Del Papa, Mariangela De Ioanni, Lorenzo Moretti, Ezio Bonifacio, Katia Fettucciari, Tiziana Zei, Franca Falzetti, Mauro Di Ianni, Antonio Tabilio,
Abstract T cell homeostasis is regulated by several molecules among which Interleukin 7 (IL-7) plays an essential role for survival and homeostatic proliferation of peripheral naive T cells. In a previous study we demonstrated whether human mesenchymal cells could be engineered with IL-7 gene to produce functional level of this cytokine. Now we analysed the impact of different quantities of IL-7 produced by mesenchymal cells on survival and proliferation of a negative immunoselected naive (CD3+/CD45RA+) ...
Tópico(s): CAR-T cell therapy research
2006 - Elsevier BV | Blood
Mauro Di Ianni, Beatrice Del Papa, Lorenzo Moretti, Maria De Ioanni, Ezio Bonifacio, Franca Falzetti, Antonio Tabilio,
Abstract Despite much investigation into T regulatory cells (Tregs), little is known about the mechanism controlling their recruitment and function. Since mesenchymal cells (MSCs) exert an immune regulatory function and suppress T cell proliferation, this in vitro study investigated their role in Treg recruitment and function. hMSCs and different T cell populations (CD3+, CD3+/CD45RA+, CD3+/CD45RO+, CD4+/CD25+, CD4+/CD25+/CD45RO+, CD4+/CD25+/CD45RA+) from healthy donors were co-cultured for up to 15 ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2007 - Elsevier BV | Blood
... da Ugolino stesso definita reclusione, estesa poi da Bonifacio VIII a tutte le comunità monastiche femminili con ...
Tópico(s): Libraries, Manuscripts, and Books
2006 - St. Bonaventure University | Franciscan studies
Mauro Di Ianni, Beatrice Del Papa, Maria De Ioanni, Adelmo Terenzi, Paolo Sportoletti, Lorenzo Moretti, Franca Falzetti, Ezio Bonifacio, Maria Paola Martelli, Antonio Tabilio,
Key players in human T-cell development after T- cell-depleted allogeneic stem cell transplants are bone marrow stroma and interleukin-7 (IL-7). We engineered human stromal cells with the IL-7 gene and studied the effects on T cells in vitro and on in vivo immunological reconstitution in NOD/SCID mice. Transduced mesenchymal cells were negative for CD45 and CD14, positive for CD90 (98.15%), CD105 (87.6%), and STRO-1 (86.7%) and stably produced IL-7 (16.37±2SD pg/ml). In cocultures with T cells, IL-7 ...
Tópico(s): Hematopoietic Stem Cell Transplantation
2005 - Elsevier BV | Biology of Blood and Marrow Transplantation
... ricostruire. Se nelle vicende della contestata elezione di Bonifacio VIII Ubertino aveva disconosciuto esplicitamente l’autorità papale ... ormai ribelle e in analogia con quelle del papa, che anzi sarebbe il committente del primo scritto, ...
Tópico(s): Renaissance and Early Modern Studies
2012 - St. Bonaventure University | Franciscan studies