Franco Zanotti, F. Guerrieri, G. Capozza, J Houštěk, Severino Ronchi, Sergio Papa,
The F 0 I protein of apparent M r 27000, previously characterized [(1988) Eur. J. Biochem. 173, 1–8] as a genuine component of bovine heart F 0 , has been sequenced and shown to be identical with the nucleus encoded 24668 Da protein characterized earlier [(1987) J. Mol. Biol. 197, 89–100]. It is directly shown by proteolytic cleavage and reconstitution experiments that this protein, denoted here as PVP from the single‐letter codes of the last three residues of the N‐terminus, is involved in proton conduction ...
Tópico(s): RNA and protein synthesis mechanisms
1988 - Wiley | FEBS Letters
F. Guerrieri, Franco Zanotti, Giuseppe Capozza, Gina Colaianni, Severino Ronchi, Sergio Papa,
Proteolytic digestion of F1-depleted submitochondrial particles (USMP), reconstitution with isolated subunits and titration with inhibitors show that the nuclear-encoded PVP protein, previously identified as an intrinsic component of bovine heart F0 (F01) (Zanotti, F. et al. (1988) FEBS Lett. 237, 9-14), is critically involved in maintaining the proper H+ translocating configuration of this sector and its correct binding to the F1 catalytic moiety. Trypsin digestion of USMP, under conditions leading ...
Tópico(s): RNA modifications and cancer
1991 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Bioenergetics
Tiziana Cocco, Michele Lorusso, Anna Maria Sardanelli, Michele Minuto, Severino Ronchi, Gabriella Tedeschi, Sergio Papa,
Structural and functional characteristics of subunits of bovine heart cytochrome-c reductase have been investigated by controlled digestion of soluble and membrane-reconstituted purified bc1 complex and direct amino acid sequencing of native and digested protein subunits. The results obtained show that the N-terminal segments of core protein II and the 14-kDa protein extend at the periphery of the complex, protruding into the inner matrix space. The Fe-S protein, located at the outer C-periphery ...
Tópico(s): Mass Spectrometry Techniques and Applications
1991 - Wiley | European Journal of Biochemistry
Produção Nacional
Revisado por pares
Fernanda Papa Spada, Severino Matias de Alencar, Eduardo Purgatto,
Jackfruit (Artocarpus heterophyllus Lam) occurs abundantly in Brazil, but its seeds are often underutilized in food nutrition. Previously, we showed that roasted jackfruit seeds are an innovative source of chocolate aroma. In this study, we characterized the volatile content of experimental beverages containing jackfruit seed flours as compared to non-alkaline cocoa powder. The three key results of this study were that (i) the fermented jackfruit seed flour beverage (FJSBev) was similar to the non- ...
Tópico(s): Sensory Analysis and Statistical Methods
2022 - Elsevier BV | Future Foods
Elisa Tassano, Mariasavina Severino, Silvia Rosina, Riccardo Papa, Domenico Tortora, Giorgio Gimelli, Cristina Cuoco, Paolo Picco,
Deletions of the long arm of chromosome 18 cause a common autosomal syndrome clinically characterized by a protean clinical phenotype.We report on a 16-month-old male infant affected by fever attacks apparently unrelated with any infectious or inflammatory symptoms, growth retardation, bilateral vertical talus, congenital aural atresia, dysmorphisms, mild psychomotor delay, and peculiar neuroradiological features. Array-CGH analysis revealed one of the smallest 18q22.3q23 interstitial deletions ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2016 - BioMed Central | Molecular Cytogenetics
Produção Nacional
Revisado por pares
Fernanda Papa Spada, Dimitrios P. Balagiannis, Eduardo Purgatto, Severino Matias de Alencar, Solange Guidolin Canniatti‐Brazaca, Jane K. Parker,
The seeds of the jackfruit (Artocarpus heterophyllus Lam.) are an abundant waste-stream in Brazil and a potential source of chocolate aroma. The aim of the study was to characterise the aroma compounds in flours prepared from the roasted jackfruit seeds and compare them with a typical Brazilian cocoa powder. Jackfruits seeds were either left untreated, acidified or fermented before drying and roasting. The volatiles were extracted using solid phase micro extraction or solid phase extraction and analysed ...
Tópico(s): Fermentation and Sensory Analysis
2021 - Elsevier BV | Food Chemistry
Sergio Papa, F. Guerrieri, Franco Zanotti, J Houštěk, Giuseppe Capozza, Severino Ronchi,
By means of protein sequencing, labelling with thiol reagents and reconstitution studies it is shown that the carboxyl-terminal region of the PVP protein (F0I subunit, nuclear-encoded protein of Mr 25,000) of mitochondrial F0 promotes transmembrane proton conduction by F0 and the sensitivity of this process to oligomycin.
Tópico(s): RNA and protein synthesis mechanisms
1989 - Wiley | FEBS Letters
Giulio Zuccaro, V. Albanese, F. Cacace, C. Mercuri, Fabrice Papa, A. G. Pizza, S. Sergio, Severino Mavhiki, Adolfo Santini, Nicola Moraci,
The paper describes technical and functional surveys on COM buildings (Mixed Operative Centre). This activity started since 2005, with the contribution of both Italian Civil Protection Department and the Regions involved. The project aims to evaluate the efficiency of COM buildings, checking not only structural, architectonic and functional characteristics but also paying attention to surrounding real estate vulnerability, road network, railways, harbours, airports, area morphological and hydro‐geological ...
Tópico(s): Structural Health Monitoring Techniques
2008 - American Institute of Physics | AIP conference proceedings
Tópico(s): Theology and Canon Law Studies
2018 - SAGE Publishing | Theological Studies
Produção Nacional
Revisado por pares
Alan Giovanini de Oliveira Sartori, Fernanda Papa Spada, Victor Pena Ribeiro, Pedro Luiz Rosalen, Masaharu Ikegaki, Jairo Kenupp Bastos, Severino Matias de Alencar,
Abstract Brown propolis from permanent preservation and reforestation areas of southern Brazil have attracted international commercial interest and have a unique composition, although little is known about their botanical origins, which are the plant resins used by bee foragers to produce propolis. Hence, the volatile profiles of organic and non-organic brown propolis and resins of suspected botanical origins— Araucaria angustifolia , Pinus elliott and Pinus taeda —were determined using static headspace ...
Tópico(s): Essential Oils and Antimicrobial Activity
2021 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Priscila Vieira da Silva, Juliana Severino Lupinetti Noberto, Ariane Barbosa Rodrigues Del Papa, Cíntia Aparecida Damo Simões, Sandrine Bittencourt Berger, Andreza Maria Fábio Aranha,
Abstract The early loss of anterior primary teeth is frequent in the pediatric dentistry clinic and it is associated with extensive caries or dental trauma. The purpose of this study was to report two cases of aesthetic-functional rehabilitation due to early loss of anterior primary teeth, with the aid of fixed space maintainers of the tube-bar type. In the first case, a 4-year-old female child referred for dental treatment is reported. During clinical examination, several restorations in the posterior ...
Tópico(s): Dental Health and Care Utilization
2019 - UNIVERSIDADE PITÁGORAS UNOPAR | Journal of Health Sciences
Elena Bonora, Sanjiban Chakrabarty, Georgios Kellaris, Makiko Tsutsumi, Francesca Bianco, Christian Bergamini, Farid Ullah, Federica Isidori, Irene Liparulo, Chiara Diquigiovanni, Luca Masin, Nicola Rizzardi, Mariapia Giuditta Cratere, Elisa Boschetti, Valentina Papa, Alessandra Maresca, Giovanna Cenacchi, Rita Casadio, Pier Luigi Martelli, Ivana Matera, Isabella Ceccherini, Romana Fato, Giuseppe Raiola, Serena Arrigo, Sara Signa, Angela Rita Sementa, Mariasavina Severino, Pasquale Striano, Chiara Fiorillo, Tsuyoshi Goto, Shumpei Uchino, Yoshinobu Oyazato, Hisayoshi Nakamura, Sushil Kumar Mishra, Yu‐Sheng Yeh, Takema Kato, Kandai Nozu, Jantima Tanboon, Ichiro Morioka, Ichizo Nishino, Tatsushi Toda, Yu-ichi Goto, Akira Ohtake, Kenjiro Kosaki, Yoshiki Yamaguchi, Ikuya Nonaka, Kazumoto Iijima, Masakazu Mimaki, Hiroki Kurahashi, Anja Raams, Alyson W. MacInnes, Mariel Alders, Marc Engelen, Gabor E. Linthorst, Tom de Koning, Wilfred F.A. den Dunnen, Gerard Dijkstra, Karin van Spaendonck, Dik C. van Gent, Eleonora Aronica, Paolo Picco, Valério Carelli, Marco Seri, Nicholas Katsanis, Floor A.M. Duijkers, Mariko Taniguchi‐Ikeda, Roberto De Giorgio,
Abstract Abnormal gut motility is a feature of several mitochondrial encephalomyopathies, and mutations in genes such as TYMP and POLG, have been linked to these rare diseases. The human genome encodes three DNA ligases, of which only one, ligase III (LIG3), has a mitochondrial splice variant and is crucial for mitochondrial health. We investigated the effect of reduced LIG3 activity and resulting mitochondrial dysfunction in seven patients from three independent families, who showed the common occurrence ...
Tópico(s): Neurological diseases and metabolism
2021 - Oxford University Press | Brain
Produção Nacional
Revisado por pares
David Henrique Xavier Barbosa, Danielle da Nóbrega Alves, Patrícia Néris Andrade, Marianna Vieira Sobral, Isione Oliveira Castro, Gleycyelly Rodrigues de Araujo, Severino Matias de Alencar, Fernanda Papa Spada, André Azevedo dos Santos, Pedro Luiz Rosalen, Ricardo Dias de Castro,
The plant species
Tópico(s): Plant chemical constituents analysis
2024 - Taylor & Francis | Drug and Chemical Toxicology
Produção Nacional
Revisado por pares
Fernanda Papa Spada, Severino Matias de Alencar, Stanislau Bogusz, Eduardo Purgatto,
Cocoa is the third most important global agricultural export commodity. However, because it is a crop sensitive to climatic change, there has been an active search for cocoa substitutes worldwide. Roasted jackfruit seeds were previously described as having a chocolate aroma and are affordable and accessible. In this study, we characterized and identified by SPME-GC-O and SPME-GC-MS the aroma profile of cocoa-based beverages formulated with jackfruit seed flour as a natural cocoa substitute. Our ...
Tópico(s): Biochemical and biochemical processes
2024 - Multidisciplinary Digital Publishing Institute | Fermentation
Lucio Annunziato, Mauro Cataldi, Giuseppe Pignataro, Agnese Secondo, Pasquale Molinaro,
... Pannaccione A, Ambrosino P, Pignataro G, Fiorino F, Severino B, Gatta E, Sisalli M, Milanese M, Scorziello ...
Tópico(s): Ion channel regulation and function
2007 - Lippincott Williams & Wilkins | Stroke
Riccardo Papa, Marta Rusmini, Stefano Volpi, Gianluca Dell’Orso, Maria Carla Giarratana, Roberta Caorsi, Stefano Giardino, Paola Bocca, Patrizia Barone, Mariasavina Severino, Isabella Ceccherini, Marco Gattorno, Maura Faraci,
Tópico(s): Diabetes and associated disorders
2021 - Wiley | Pediatric Allergy and Immunology
Gianni Canova, Severino Salvemini,
Tópico(s): Italian Literature and Culture
2014 - Springer Science+Business Media | Electronic Markets
Annalisa Caputo, Silvia Papa, Giovanna Manzi, Domenico Laviola, Tommaso Recchioni, Paolo Severino, Carlo Lavalle, Viviana Maestrini, Massimo Mancone, Roberto Badagliacca, Carmine Dario Vizza,
Abstract Purpose of Review The purpose of this review is to overview the most relevant and recent knowledge regarding medical management in pulmonary arterial hypertension (PAH) . Recent Findings Evidence has shown that PAH patients’ quality of life and prognosis depend on the capability of the RV to adapt to increased afterload and to fully recover in response to substantially reduced pulmonary vascular resistance obtained with medical therapy. Data from recent clinical studies show that more aggressive ...
Tópico(s): Cardiac Valve Diseases and Treatments
2023 - Springer Science+Business Media | Current Heart Failure Reports
Giovanna Manzi, Tommaso Recchioni, Alexandra Mihai, Paolo Severino, Lucia Ilaria Birtolo, Domenico Filomena, Andrea D’Amato, Massimo Mancone, Silvia Papa, Roberto Badagliacca, Carmine Dario Vizza,
Tópico(s): Cardiac Valve Diseases and Treatments
2025 - Oxford University Press | European Heart Journal Supplements
S. Coppari, G. Di Pasquale, A. Goretti, María Fernanda Papa, S. Papa, Giacomo Persi Paoli, A. G. Pizza, Severino Mavhiki, Adolfo Santini, Nicola Moraci,
The paper summarizes the results of the in progress EU Project titled TRIPOD (Training Civil Engineers on Post‐Earthquake Safety Assessment of Damaged Buildings), funded under the Leonardo Da Vinci program. The main theme of the project is the development of a methodology and a learning platform for the training of technicians involved in post‐earthquake building safety inspections. In the event of a catastrophic earthquake, emergency building inspections constitute a major undertaking with severe ...
Tópico(s): Education, Management, Technology, Human Resources
2008 - American Institute of Physics | AIP conference proceedings
Produção Nacional
Revisado por pares
Taisa Maria Mendes Matuiama Machado, Iara Gonçalves Aquino, Marcelo Franchin, Miguel Zárraga, Daniel Bustos, Fernanda Papa Spada, Marcelo Henrique Napimoga, Juliana Trindade Clemente‐Napimoga, Severino Matias de Alencar, Bruna Benso, Henrique Ballassini Abdalla,
Tópico(s): Neurobiology and Insect Physiology Research
2024 - Elsevier BV | European Journal of Pharmacology
Produção Nacional
Revisado por pares
Yolanda Henrichs Garcia Bandeira Bastos, Cristiano Silva Ferreira, Gustavo Mendes Gomes, Kléber da Cunha Peixoto Júnior, Letícia Patrão de Macedo Gomes, Frederico Ozanam Papa, André Maciel Crespilho,
Os corantes Panótico Rápido e Giemsa são frequentemente utilizados para a avaliação de células de linhagem espermatogênica, porém nenhuma destas colorações foi desenvolvida especificamente para o processamento tintorial desse tipo celular. Como até presente não existe consenso na literatura sobre qual das técnicas de coloração permite a melhor visualização das células germinativas testiculares, o objetivo deste estudo foi determinar a melhor coloração para esfregaços obtidos por punção biópsia aspirativa ...
Tópico(s): Reproductive Biology and Fertility
2016 - Editora Universidade Severino Sombra | Revista de Saúde
Yolanda Henrichs Garcia Bandeira Bastos, Cristiano Ferreira da Silva, Gustavo Mendes Gomes, Kleber Da Cunha Peixoto Júnior, Letícia Patrão de Macedo Gomes, Frederico Ozanam Papa, André Maciel Crespilho,
Os corantes Panótico Rápido e Giemsa são frequentemente utilizados para a avaliação de células de linhagem espermatogênica, porém nenhuma destas colorações foi desenvolvida especificamente para o processamento tintorial desse tipo celular. Como até presente não existe consenso na literatura sobre qual das técnicas de coloração permite a melhor visualização das células germinativas testiculares, o objetivo deste estudo foi determinar a melhor coloração para esfregaços obtidos por punção biópsia aspirativa ...
Tópico(s): Reproductive Biology and Fertility
2015 - Editora Universidade Severino Sombra | Revista de Saúde
Yolanda Henrichs Garcia Bandeira Bastos, Cristiano Ferreira da Silva, Gustavo Mendes Gomes, Kleber Da Cunha Peixoto Júnior, Letícia Patrão de Macedo Gomes, Frederico Ozanam Papa, André Maciel Crespilho,
Os corantes Panótico Rápido e Giemsa são frequentemente utilizados para a avaliação de células de linhagem espermatogênica, porém nenhuma destas colorações foi desenvolvida especificamente para o processamento tintorial desse tipo celular. Como até presente não existe consenso na literatura sobre qual das técnicas de coloração permite a melhor visualização das células germinativas testiculares, o objetivo deste estudo foi determinar a melhor coloração para esfregaços obtidos por punção biópsia aspirativa ...
Tópico(s): Reproductive Biology and Fertility
2015 - Editora Universidade Severino Sombra | Revista de Saúde
C. Iannone, M. R. Pellico, Letizia Corinna Morlacchi, V. Rossetti, Marco Vicenzi, Giorgia Trignani, Paolo Airò, Margherita Saracco, Annamaria Iagnocco, Lorenzo Beretta, Adriana Severino, Eleonora Zaccara, F. Cacciapaglia, Stefano Stano, Veronica Codullo, Federica Meloni, Silvia Cavalli, Antonina Minniti, Paola Faggioli, Francesco Blasi, Roberto Caporali, Nicoletta Del Papa,
Background: Lung transplantation (LT) shows promise for managing advanced interstitial lung disease (ILD) in systemic sclerosis (SSc) patients. However, concerns remain among surgeons due to SSc multiorgan involvement, complexities related to esophageal dysfunction, and heightened post-transplant complications. Although literature has focused on survival rates, comprehensive studies about LT outcomes with particular regard to SSc activity and progression are still lacking. Objectives: To evaluate in SSc patients ...
Tópico(s): Systemic Sclerosis and Related Diseases
2024 - BMJ | Annals of the Rheumatic Diseases
Irene Toldo, Francesco Brunello, Paola Cavasin, Margherita Nosadini, Stefano Sartori, Anna Chiara Frigo, Roberto Mai, Veronica Pelliccia, Maria Margherita Mancardi, Pasquale Striano, Marisavina Severino, Federico Zara, Romana Rizzi, Susanna Casellato, Gabriella Di Rosa, Mario Mastrangelo, Alberto Spalice, M Budetta, Luca De Palma, Renzo Guerrini, Dario Pruna, Duccio Maria Cordelli, Vito Sofia, Amanda Papa, Valentina Chiesa, Francesca Ragona, Pasquale Parisi, Alfredo D’Aniello, Pierangelo Veggiotti, Filippo Dainese, Lucio Giordano, Laura Licchetta, Paolo Tinuper, G. D’Orsi, Matteo Cassina, Renzo Manara,
Subcortical band heterotopia (SBH) is a rare malformation of the cortical development characterized by a heterotopic band of gray matter between cortex and ventricles. The clinical presentation typically includes intellectual disability and epilepsy.To evaluate if the Extended Glasgow Outcome Scale-pediatric version (EGOS-ped) is a feasible tool for evaluating the functional disability of patients with (SBH).Cross-sectional multicenter study of a cohort of 49 patients with SBH (female n = 30, 61%), recruited ...
Tópico(s): Spinal Dysraphism and Malformations
2023 - Elsevier BV | Pediatric Neurology
Roberto Badagliacca, Manuela Reali, Carmine Dario Vizza, Roberto Poscia, Beatrice Pezzuto, Cristina Gambardella, Silvia Papa, Mario Mezzapesa, Martina Nocioni, F Fedele, Benjamin H. Freed, Nicole M. Bhave, Wendy Tsang, Mardi Gomberg‐Maitland, Victor Mor‐Avi, Anisha Patel, Roberto M. Lang, Noah Liel‐Cohen, M. Yaacobi, Hugo Guterman, P. Jurzak, Julien Ternacle, Romain Gallet, A. Bensaid, Martin Kloëckner, J.-L. Monin, Pascal Guéret, J.-L. Dubois-Randé, Pey Lian Lim, Tatsuhiko Otsuka, M. Suzuki, H. Yoshikawa, Go Hashimoto, Yuh Ishikawa, Takuya Osaki, Hiroyuki Masai, T Ono, M. Yamamoto, Keisuke Sugi, M. Satendra, L. Sargento, Carla Sousa, A Arsénio, Nuno Lousada, Roberto Palma dos Reis, S. Wang, Y. Lam, M. Liu, Fang Fang, Qing Shang, Xiaoyu Luo, J. Wang, Jiahui Sun, John E. Sanderson, Yu Chen, SF De Marchi, Eugene S. Hopp, Stig Urheim, Anders Hervold, K Murbrach, Richard J. Massey, Espen W. Remme, Per Kristian Hol, Svend Aakhus, Alberto Bouzas‐Mosquera, Jesús Peteiro, Francisco J. Broullón, Norma Angélica Díaz García, J. Rodriguez Garrido, Dalmer Ruiz, J. Yanez Wonenburger, Beatriz Bouzas Zubeldía, R. Fabregas Casal, Alfonso Castro Beiras, Thierry Le Tourneau, Catherine Sportouch, Christelle Foucher, Béatrice Delasalle, Jean Rosso, Yannick Neuder, Jean‐Noël Trochu, Jérôme Roncalli, Patricia Lemarchand, Alejandro Manrique, Dawod Sharif, Amal Sharif‐Rasslan, Camilia Shahla, Adeel Ahmad Khalil, Uri Rosenschein, Laura Monti, M. Tramarin, Margherita Calcagnino, Veronica Lisignoli, Barbara Nardi, Luca Balzarini, Afshin Khalatbari, James D. Mills, Adrian Chenzbraun, Alexis Théron, Pierre Morera, Noemi Resseguier, Franck Thuny, A Riberi, Rina Dalva Neubarth Giorgi, Frederic Collart, Gabriel B. Habib, Jean-François Aviérinos, D. Liu, Kangxin Hu, Markus Niemann, Sandra M. Herrmann, Peter Gaudron, W Voelker, G. Ertl, Bart Bijnens, Frank Weidemann, Guy Lenders, J.M. Bosmans, Paul L. Van Herck, Inez Rodrigus, Marc J. Claeys, Christiaan Vrints, Bernard P. Paelinck, Federico Veronesi, Laura Fusini, Gloria Tamborini, Paola Gripari, Francesco Maffessanti, Oana Mirea, Francesco Alamanni, Mauro Pepi, Enrico G. Caiani, Zied Frikha, Ihsen Zaïri, Walid Saib, Sana Fennira, F. Ben Moussa, S. Kammoun, Kaies Mrabet, Aymen Ben Yaala, Lobna A. Said, M. Ghannouchi, Guido Carlomagno, Luigi Ascione, Chiara Sordelli, Raffaele Iengo, Sergio Severino, A. D'andrea, Raffaele Calabrò, P. Caso, Magdalena Mizia, Katarzyna Mizia‐Stec, A. Sikora-Puz, Klaudia Gieszczyk-Strózik, Artur Chmiel, Maciej Haberka, Damian Hudziak, Marek Jasiński, Zbigniew Gąsior, Stanisław Woś, Patric Biaggi, Cordula Felix, C Gruner, Sabine Hohlfeld, B. Herzog, Oliver Gaemperli, Juerg Gruenenfelder, Roberto Corti, Felix C. Tanner, Dominique Béttex, Sylva Kovalová, Josef Nečas, F. Dominguez Rodriguez, Vanessa Moñivas, Susana Mingo Santos, Inés García‐Lunar, Pablo García‐Pavía, Jesús G. Mirelis, Isabel Zegrí, Miguel Ángel Broc Cavero, Hui Kyung Jeon, D. Lee, Ho‐Joong Youn, Hyoseung Shin, Junghan Yoon, H. Chung, Eue-Keun Choi, J. Kim, P. Min, B. Lee, Yong‐Hoon Yoon, Bum‐Kee Hong, HJ Kwon, Se‐Joong Rim, Valentina Petronilli, Sara Cimino, Lucia De Luca, F Cicogna, Luca Arcari, Marco Francone, Carlo Iacoboni, Luciano Agati, L. Halmai, Paul Atkinson, Attila Kardos, Richard Bogle, P. Meimoun, Gauthier Flahaut, Vincent Charles, Yohan Villain, Jérôme Clerc, A.-L. Germain, F. Elmkies, H. Zemir, A. Luycx-Bore, K. Kim, Jie Song, H. Jeong, Han-Ki Yoon, Young Geun Ahn, M. Jeong, J. Cho, J. Park, Ji‐Hoon Kang, Osama Tolba, Mohamed El‐Shanshory, Nagla A. El‐Shitany, E.-S. El-Hawary, Galaleldin Nagib Elkilany, Osama Tolba, Mohamed El‐Shanshory, A. E.-A. El-Shitany, Eslam E. Elhawary, Galal Elkilany, Luisa Di Costanzo, Sergio Buccheri, Ines Monte, G Curatolo, P. Crapanzano, Luigi Di Pino, Margherita Stefania Rodolico, A. Blundo, Samuele Leggio, Corrado Tamburino, Emma Rees, R. Hocking, Frank Dunstan, Martin Lewis, K. Tunstall, Aled Rees, Julian Halcox, A. G. Fraser, Antenor Rodrigues, L. Guimaraes, Joana Guimarães, Cinzia Monaco, Adriana Cordovil, Eduardo Carvalho Lira, Maria João Vieira, Cláudio Henrique Fischer, Chihomi Nomura, Samira Saady Morhy, Bruno Reversade, Amanda da Rocha Cogo, Rahul Sharma, Manuela Bartesaghi, Luca Pomidori, Buddha Basnyat, Simone Rosa Taddei, E. Picano, Rosa Sicari, Lorenza Pratali, M. Satendra, L. Sargento, Carla Sousa, Nuno Lousada, Roberto Palma dos Reis, Lilia Zakhama, Sana Sioua, S. Naffati, A. Marouen, Elhem Boussabah, R. Kadour, Moez Thameur, S. Benyoussef, Davide Vanoli, Urban Wiklund, Michael Y. Henein, Ulf Näslund, Per Lindqvist, M Palinský, J Petrovičová, M. Pirscova, Karl Korpi, H. Blafield, H. Suomi,
Purpose: Idiopathic pulmonary arterial hypertension (IPAH) prognosis depends on the capability of the right ventricle (RV) to preserve its function in face of increased afterload.We hypothesize that, as for the left ventricle, right intra-ventricular (IVD) dyssynchrony may have a negative effect on the overloaded RV.The aim of the study was to assess right IVD by incorporating activation times of longitudinal deformation across all RV segments, representing the longitudinal deformation the major contribution ...
Oxford University Press
Alessandro Santaniello, Chiara Bellocchi, Silvia Laura Bosello, Enrico De Lorenzis, G. Natalello, Nicoletta Del Papa, Silvia Cavalli, Devis Benfaremo, Gabriele C. DeLuca, Corrado Campochiaro, Lorenzo Cavagna, Veronica Codullo, Gaia Montanelli, Adriana Severino, Monica Caronni, Barbara Vigone, Carlomaurizio Montecucco, Lorenzo Dagna, Gianluca Moroncini, Roberto Caporali, Lorenzo Beretta,
Background Interstitial lung disease (ILD) is a severe complication of systemic sclerosis (SSc) that may lead to irreversible loss of lung function and increased mortality. Patterns of disease progression (PODs) in SSc-ILD are poorly characterized. Objectives To define PODs in SSc-ILD patients that may have clinical implications for patient stratification and clinical trial design. Methods Patients with SSc at risk for ILD were recruited in 6 tertiary referral centers. Inclusion criteria were: a) Disease duration < ...
Tópico(s): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
2023 - BMJ | Annals of the Rheumatic Diseases
Claudia Iannone, Maria Rosa Pellico, Letizia Corinna Morlacchi, V. Rossetti, Marco Vicenzi, Lorenzo Beretta, Adriana Severino, Paolo Airò, Fabio Cacciapaglia, Veronica Codullo, Paola Faggioli, Annamaria Iagnocco, Federica Meloni, Lorena Mercante, Marta Saracco, Stefano Stano, Eleonora Zaccara, Antonina Minniti, Silvia Cavalli, Giorgia Trignani, Francesco Blasi, Mario Nosotti, Massimo Boffini, Roberto Caporali, Nicoletta Del Papa,
Abstract Objectives Lung transplantation (LuTx) is a life-saving intervention for SSc patients with end-stage lung disease. The aim of this study was to evaluate patients’ survival and LuTx outcomes on systemic disease manifestations. Methods A retrospective evaluation was conducted on SSc patients who underwent LuTx between 2010 and 2021. Outcomes assessed at baseline, 6, 12 and 24 months post-LuTx included skin involvement by modified Rodnan skin score (mRSS), and global disease activity using a ...
Tópico(s): Dermatologic Treatments and Research
2024 - Oxford University Press | Lara D. Veeken
Produção Nacional
Revisado por pares
Marcelo Franchin, Ana Sofia Martelli Chaib Saliba, Anderson dos Santos Ramos, Fernanda Papa Spada, Daniela Coelho dos Santos, Maria Leandro, Eduardo Nunes Gonçalves, Bruno Bueno‐Silva, Yandong Xu, Kai Wang, Jason Bennett, Thiago M. Cunha, Severino Matias de Alencar, Daniel Granato,
Tópico(s): Microencapsulation and Drying Processes
2025 - Elsevier BV | International Journal of Biological Macromolecules