John V. Shoemaker, E. B. Gleason, Ch. David, M. I. Copinger, Dr. L. L. Silverthorn, I. C. Reshower, John Griggs, J. Knowles,
... with the Eruption of the First Upper Molar, Parosmia, The Fundus Oculi in Diseases of the Ear, ...
1905 - Gale Group | NCCO-STM 1of2
Basile N. Landis, Johannes Frasnelli, Ilona Croy, Thomas Hummel,
Parosmia and phantosmia relate to distorted odor perceptions. Little is known about their clinical significance. Measuring phantosmia and parosmia is still not possible. Today, assessment of parosmia or phantosmia relies mainly upon the patient's ... imaging) and filled in a questionnaire with four parosmia questions and six questions regarding characteristics and severity of the parosmia. These responses formed the bases of a numerical parosmia score.Patients with parosmia showed significantly lower parosmia ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2010 - Wiley | The Laryngoscope
Hideaki Shiga, Koichi Okuda, Junichi Taki, Naoto Watanabe, Hisao Tonami, Seigo Kinuya, Takaki Miwa,
... and olfactory bulb (OB) differs between patients with parosmia with and without hyposmia after upper respiratory tract infection (URTI). Methods Twenty patients with parosmia after URTI were enrolled in this study (15 ... recognition thresholds (≤2.0) who still complained of parosmia (parosmia group), and 10 patients with T&T odor recognition thresholds >2.0 (parosmia and hyposmia group). Results The nasal thallium‐201 ... the olfactory cleft was significantly higher in the parosmia group than in the parosmia and hyposmia group ( ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2019 - Wiley | International Forum of Allergy & Rhinology
... review was to summarize the current knowledge on parosmia and phantosmia and introduce support and treatment algorithms ... the two qualitative olfactory disorders. Recent literature regarding parosmia has revealed that patients with the disorder are ... MOT is also effective against COVID-19-induced parosmia. Parosmia, the distortion of smells, is a symptom in ... to 5% of the general population. Etiologies of parosmia include sinonasal diseases, viruses, surgeries, traumatic brain injury, neurological and psychiatric conditions, toxic chemicals, and medications. Parosmia has seen a surge in cases since the ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2023 - Springer Science+Business Media | Current Otorhinolaryngology Reports
David K. Lerner, Katherine L. Garvey, Annie E. Arrighi‐Allisan, Andrey Filimonov, Peter Filip, Janki Shah, Benjamin Tweel, Anthony Del Signore, Madeleine Schaberg, Patrick Colley, Satish Govindaraj, Alfred Marc Iloreta,
... time‐course, and quality of life implications for parosmia among coronavirus disease (COVID)‐related olfactory dysfunction patients. ... of 148 (64.1%) of 231 respondents reported parosmia at some point. Parosmia developed within 1 week of any COVID‐19 ... after symptom onset in 43.4% of respondents. Parosmia was associated with significantly better quantitative olfactory scores ... vs. 23.2, P = .113). Participants who developed parosmia at any point were significantly younger and less ... chronic sinusitis than those who did not develop parosmia (40.2 vs. 44.9 years, P = .007; ...
Tópico(s): Salivary Gland Disorders and Functions
2021 - Wiley | The Laryngoscope
Abbas Yousefi-Koma, Sara Haseli, Mehrdad Bakhshayesh Karam, Nasim Raad, Mahboobeh Karimi‐Galougahi,
... and includes quantitative (hyposmia or anosmia) and qualitative (parosmia or phantosmia) olfactory dysfunction. Parosmia is defined as alteration of olfactory perception in the presence of real olfactory stimulation. Patients with parosmia often describe perceiving the smell of something that ... Gudziol H et al.Gray matter alterations in parosmia.Neuroscience. 2011; 177: 177-182https://doi.org/10. ... have been performed to evaluate the pathophysiology of parosmia, and none in parosmia due to COVID-19. We have previously reported ...
Tópico(s): Essential Oils and Antimicrobial Activity
2021 - Elsevier BV | Academic Radiology
Rasheed Ali Rashid, Ameer A. Alaqeedy, Raid M. Al-Ani,
Although parosmia is a common problem in the era of the COVID-19 pandemic, few studies assessed the demographic ... of various options of treatment of individuals with parosmia due to COVID-19 infection. The study was ... Iraq, on patients with a chief complaint of parosmia due to COVID-19 disease. The study involved ... recorded and analyzed. Out of 268 patients with parosmia, there were 197 (73.5%) females. The majority ... majority of the patients were suffering from severe parosmia (65.7%). Around 3 quarters of the cases ...
Tópico(s): Facial Nerve Paralysis Treatment and Research
2021 - Springer Nature | Indian Journal of Otolaryngology and Head & Neck Surgery
Nasim Raad, Jahangir Ghorbani, Ali Safavi Naeini, Neda Tajik, Mahboobeh Karimi‐Galougahi,
... and anosmia) and qualitative, which is subdivided into parosmia (distorted odor perception) and phantosmia (odor perception in ... due to other etiologies,3 and data on parosmia secondary to COVID-19 are scarce. In this ... characteristics, and quality of life in patients with parosmia due to COVID-19. We published an online ... in the analysis. To assess the impact of parosmia on quality of life, we used a modified ... questionnaire. Of these participants, 140 (10.8%) had parosmia and COVID-19 confirmed by PCR. Demographic and ...
Tópico(s): Essential Oils and Antimicrobial Activity
2021 - Wiley | International Forum of Allergy & Rhinology
Alexander Wieck Fjældstad, Barry Smith,
... food in both patients with olfactory loss and parosmia. How the different types of olfactory dysfunction differ ... differ between participants with olfactory loss (n = 271), parosmia (n = 251), and normosmic controls (n = 166). Cooking ... cooking were also found between olfactory loss and parosmia. Food items were less familiar in participants with olfactory loss and parosmia, while the ratings of liking food items differed between olfactory loss and parosmia, indicating the importance of adapting ingredients in meals ...
Tópico(s): Advanced Chemical Sensor Technologies
2022 - Multidisciplinary Digital Publishing Institute | Foods
Paolo Boscolo–Rizzo, Claire Hopkins, Anna Menini, Michele Dibattista, Emilia Cancellieri, Nicoletta Gardenal, Margherita Tofanelli, Romina Valentinotti, Jérôme R. Lechien, Luigi Angelo Vaira, Giancarlo Tirelli,
... and at the point of evaluation to identify parosmia and phantosmia, with answers reported as a binary ... or no), and how many odors elicited the parosmia (almost every odor vs selected odors only) (see ... and at the time of psychophysical evaluation, respectively. Parosmia and phantosmia arose at a median interval of ... qualitative OD (p = 0.335). Among patients reporting parosmia or phantosmia at any time, more severe quantitatively ... point only one third of patients who developed parosmia had recovered. This is consistent with findings by ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2022 - Wiley | International Forum of Allergy & Rhinology
Jonas Olofsson, Fredrik Ekesten, Steven Nordin,
Abstract Parosmia, distorted smell sensations, is a common consequence of respiratory virus infections. The phenomenon is not well understood ... term outcomes. We examined self-reported experiences of parosmia in a population-based sample from the Betula ... impairment at baseline. We investigated the prevalence of parosmia experiences and, using regression analyses, its relationship to ... study design, we also assessed the persistence of parosmia over 5 and 10 years prospectively. Parosmia experiences were prevalent in 4.8% of the ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2022 - Nature Portfolio | Scientific Reports
Aytuğ Altundağ, Eren Yılmaz, Mustafa Caner Kesimli,
... COVID-19) infection often causes olfactory dysfunction and parosmia may occur in some patients with olfactory dysfunction. ... MOT) for the treatment of COVID-19-induced parosmia.This study presents results of MOT performed with ... into two groups: 1) Treatment group consisted of parosmia patients who received MOT with three sets of ... different odors sequentially. 2) Control group consisted of parosmia patients who did not perform any olfactory training. ... and 9th months were recorded by applying the parosmia assessment scale to both groups. The results were ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2022 - Wiley | The Laryngoscope
Heba A. Abo El Naga, Reham S. El Zaiat, Ahmad Hamdan,
... rich plasma (PRP) in treating post-COVID-19 parosmia. A pilot study was conducted on 60 patients with post-COVID parosmia without responding to a 3-month course of ... treatment protocol for 6 weeks. The degree of parosmia was assessed before and after treatment subjectively using ... outcome was assessing the post-treatment score for parosmia 1 month after the third injection in the ... was a highly significant improvement in VAS for parosmia ( p < 0.00001) in the case group and a significant improvement in VAS for parosmia in the control group ( p = P = 0.00148). ...
Tópico(s): Nasal Surgery and Airway Studies
2022 - Springer Science+Business Media | The Egyptian Journal of Otolaryngology
Antje Müller, Basile N. Landis, Uwe Platzbecker, Vjera Holthoff‐Detto, Johannes Frasnelli, Thomas Hummel,
... rarely complain about qualitative olfactory disorders such as parosmia or phantosmia. Quantitative olfactory loss such as anosmia ... a 63-year-old woman with chemotherapy-induced parosmia leading to severe nutrition and appetite problems resulting ... the aid of a simple nose clip the parosmia could be abolished and oral food intake became possible again. Parosmia resolved gradually over an observation period of 9 ... sensitivity. The patient progressively gained appetite and weight.Parosmia can occur as a severe and potentially life- ...
Tópico(s): Advanced Chemical Sensor Technologies
2006 - SAGE Publishing | American Journal of Rhinology
Fabio Ferreli, Francesca Gaino, Elena Russo, Matteo Di Bari, Vanessa Rossi, Armando De Virgilio, Arianna Di Stadio, Giuseppe Spriano, Giuseppe Mercante,
... OD. Data on the presence of self-reported parosmia were also collected to identify any possible associations ... smell (scores 0 or 1). No patient reported parosmia at OD presentation. Patients scored their pre–COVID- ... up was 4.6 (SD, 0.9). Regarding parosmia, 38 patients reported parosmia (38.4%) at 9-month follow-up, and 3 patients reported parosmia (23.1%) among the 13 patients who reported ... of the symptom and the relative recovery pattern. Parosmia seems to be a late-onset symptom and ... 18-month follow-up. Few studies exist on parosmia's etiology and clinical course in COVID-193; ...
Tópico(s): Vagus Nerve Stimulation Research
2022 - Wiley | International Forum of Allergy & Rhinology
Jörn Lötsch, Alfred Ultsch, Maren Eckhardt, Caroline Huart, Philippe Rombaux, Thomas Hummel,
... and mechanistically still incompletely understood olfactory dysfunctions including parosmia, i.e., distorted perceptions of olfactory stimuli (n = ... olfactory hallucinations (n = 22). A higher prevalence of parosmia, and as a tendency also phantosmia, was observed ... in the right temporal lobe in patients with parosmia than in patients without parosmia. This negative direction of the differences was unique for parosmia. In anosmia, and also in phantosmia, lesions were ... of lost function in relevant brain areas whereas parosmia is more complex, requiring damaged and intact brain ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2016 - Elsevier BV | NeuroImage Clinical
Rosella Ciurleo, Simona De Salvo, Lilla Bonanno, Silvia Marino, Placido Bramanti, Fabrizia Caminiti,
Parosmia is a distorted olfactory sensation in the presence of an odor. This olfactory disorder can affect ... who experience it. Qualitative olfactory dysfunctions, such as parosmia and phantosmia, may be clinical conditions secondary to neurological diseases. The incidence of parosmia is underestimated, as well as its association with ... this paper, we show selected clinical cases of parosmia associated with neurological disorders, such as traumatic brain ... clinical cases show how the correct diagnosis of parosmia can represent the tip of the iceberg of ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2020 - Frontiers Media | Frontiers in Neurology
David T. Liu, Maha Sabha, Michael Damm, Carl Philpott, Anna Oleszkiewicz, Antje Hähner, Thomas Hummel,
... This study aims to determine the association between parosmia and clinically relevant recovery of olfactory function in ... the association between smell‐loss related factors (including parosmia and phantosmia) and clinically relevant changes in overall ... lower baseline olfactory function and those that had parosmia at the initial visit. Similarly, relevant improvements in ... baseline olfactory function and in those who had parosmia at the first visit. Clinically significant improvements in ... Conclusions This study demonstrated that the presence of parosmia is associated with clinically relevant recovery in olfactory ...
Tópico(s): Allergic Rhinitis and Sensitization
2020 - Wiley | The Laryngoscope
Zhen Yu Liu, Luigi Angelo Vaira, Paolo Boscolo–Rizzo, Abigail Walker, Claire Hopkins,
... debilitating, but the distortion of sense of smell (parosmia) that can occur as a consequence of a ... than one in three who will subsequently report parosmia. While early loss of sense of smell is ... epithelium, the underlying mechanisms of persistant loss and parosmia remain less clear. Depletion of olfactory sensory neurones, ... these treatments will also achieve comparable improvements in parosmia. This article aims to contextualise parosmia in the setting of post-viral olfactory dysfunction, ...
Tópico(s): Essential Oils and Antimicrobial Activity
2023 - BMJ | BMJ Medicine
Stephanie Hunter, Mackenzie E. Hannum, Robert Pellegrino, Maureen O’Leary, Nancy E. Rawson, Danielle R. Reed, Pamela Dalton, Valentina Parma,
... total smell loss), hyposmia (reduced sense of smell), parosmia (distorted odor perception), and phantosmia (odor sensation without ... or hyposmia, N = 135), qualitative olfactory disorder only (parosmia and/or phantosmia; N = 86), and normosmia (normal ... assessed individually, SCENTinel 1.1 discriminates between hyposmia, parosmia, and anosmia. Participants with parosmia rated common odors less pleasant than those without parosmia. We provide proof-of-concept that SCENTinel 1. ... is the only direct test to rapidly discriminate parosmia.
Tópico(s): Biochemical Analysis and Sensing Techniques
2023 - Oxford University Press | Chemical Senses
Robert Pellegrino, Joel D. Mainland, Chris Kelly, Jane K. Parker, Thomas Hummel,
... disorders that lead to odor distortion, such as parosmia (i.e. distorted odor with a known source), ... distortions were common (46%), with respondents reporting either parosmia (19%), phantosmia (11%), or both (16%). In comparison to respondents with hyposmia or anosmia, respondents with parosmia were more likely to be female, young, and ... by head trauma (P < 0.01). In addition, parosmia, compared to phantosmia or anosmia/hyposmia, was most ... distortions negatively affects the quality of life, with parosmia showing a higher range of severity than phantosmia ( ...
Tópico(s): Advanced Chemical Sensor Technologies
2021 - Oxford University Press | Chemical Senses
Mena Said, Thanh Luong, Sophie S. Jang, Morgan E. Davis, Adam S. DeConde, Carol H. Yan,
... persistent COVID-19 olfactory dysfunction (OD) commonly report parosmia. Understanding the impact of COVID-19 OD and parosmia is critical to prioritizing research and interventions. In this study we investigate the impact of parosmia and other clinical and disease characteristics on health ... reported history of smell function and presence of parosmia. HUVs were calculated using indirect (EuroQol 5-Dimension [ ... total of 89.16% of the subjects reported parosmia and 24.13% sought medical care for anosmia. ...
Tópico(s): Essential Oils and Antimicrobial Activity
2022 - Wiley | International Forum of Allergy & Rhinology
Joseph B. Gary, Liam Gallagher, Paule V. Joseph, Danielle R. Reed, David A. Gudis, Jonathan B. Overdevest,
... infection may develop qualitative olfactory dysfunction, most commonly parosmia. Our evidence-based review summarizes the evolving literature ... the clinician on the management of patients experiencing parosmia associated with COVID-19. Methods We performed a ... disease progression, prognosis, pathophysiology, diagnosis, and treatment of parosmia. Results We identified 123 unique references meeting eligibility ... to cause qualitative olfactory disturbances, the incidence of parosmia following COVID-19 is notable, and correlates negatively ...
Tópico(s): Allergic Rhinitis and Sensitization
2022 - SAGE Publishing | American Journal of Rhinology and Allergy
Thomas Bitter, F. Siegert, H. Gudziol, H Burmeister, H.-J. Mentzel, Thomas Hummel, Christian Gaser, Orlando Guntinas‐Lichius,
Parosmia is a common olfactory disorder. In this condition, odors are perceived in a different quality than ... volumes of the olfactory bulbs in patients with parosmia compared to subjects without parosmia. In order to investigate structural brain alterations in ... memory is related to disturbed olfactory sensation in parosmia.
Tópico(s): Biochemical Analysis and Sensing Techniques
2011 - Elsevier BV | Neuroscience
Emilia Iannilli, Donald A. Leopold, David E. Hornung, Thomas Hummel,
... diminished sense of smell also can suffer from parosmia. These patients with such a qualitative smell disorder ... 23 patients were investigated, 12 hyposmic patients without parosmia (HYP group) and 11 hyposmic patients with parosmia (PAR group). Both groups were matched with regard ... which differ in hyposmic patients with and without parosmia.
Tópico(s): Biochemical Analysis and Sensing Techniques
2019 - Karger Publishers | ORL
Tommaso Ercoli, Carla Masala, Ilenia Pinna, Gianni Orofino, Paolo Solla, Lorenzo Rocchi, Giovanni Defazio,
Qualitative smell/taste disorders (such as phantosmia, parosmia, phantogeusia, and parageusia) have not yet been fully characterized in patients who had COVID-19, whereas quantitative disturbances (i.e., reduction/loss of ... At the same time, the presence of phantosmia, parosmia, phantogeusia, and parageusia was investigated with a standardized ... reported in 2/17 (11.8%) patients and parosmia in 4/17 (23.5%). There were no ... scores between patients who reported phantosmia and/or parosmia and patients who did not. Phantogeusia was described ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2021 - Springer Science+Business Media | Neurological Sciences
Parosmia is a well-documented consequence of smell loss associated with Covid 19. Those who experience this ... or intervention to mitigate the condition. The AbScent Parosmia and Phantosmia support group on Facebook became an ... this paper provides information on the management of parosmia based on the experiences of over 30k patients in the AbScent Parosmia and Phantosmia group on Facebook and 6k member ...
Tópico(s): Advanced Chemical Sensor Technologies
2022 - Elsevier BV | Clinical Nutrition Open Science
Sarah Jacek, Richard J. Stevenson, Laurie A. Miller,
... TLE with an unusual presentation, an ictus-related parosmia. B.C. reported distorted perception of odor quality ... obtained at stages of the ictal cycle when parosmia symptoms were severe and when they had decreased. ... discrimination. Testing during a period of more severe parosmia suggested that B.C.'s experiences might be ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2007 - Elsevier BV | Epilepsy & Behavior
Basile N. Landis, Johannes Frasnelli, Thomas Hummel,
... of qualitative olfactory disorders such as phantosmia and parosmia is a matter of debate. Parosmia and phantosmia mainly occur in combination with post- ... with post-infectious hyposmia who reported a pleasant parosmia to selected odorants. We have called this rare ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2005 - Taylor & Francis | Acta Oto-Laryngologica
Steven Nordin, Claire Murphy, Terence M. Davidson, Carlo Quiñonez, Alfredo A. Jalowayski, Dennard W. Ellison,
The prevalence of parosmia and phantosmia among 363 chemosensory and nasal/sinus patients was studied, as was the accuracy with which our clinical ... these dysfunctions. We then investigated whether patients with parosmia or phantosmia, matched for odor intensity, perform poorer ... than 40% of the study group evidenced either parosmia (18.7%) and/or phantosmia (25.6%), a ... patient's age. Finally, the results imply that parosmia may be reflected in a discrepancy between odor ...
Tópico(s): Biochemical Analysis and Sensing Techniques
1996 - Wiley | The Laryngoscope