Catarina Ferreira, João Lobo, Luís Antunes, Paula Lopes, Cármen Jerónimo, Rui Henrique,
Cadherins seem to play and important role in prostate cancer (PCa) progression. E-cadherin loss of expression has been associated with poor prognosis; P-cadherin's role is still elusive. Although pT3 PCa is often considered "high-risk cancer," it does not exhibit an uniformly poor prognosis. Herein, we assessed the prognostic value and survival impact of E-cadherin and P-cadherin immunoexpression in pT3 PCa. Radical prostatectomy (RP) specimens from 102 pT3 PCa patients treated between 1991 and 2014 ...
Tópico(s): Cancer-related gene regulation
2018 - Springer Science+Business Media | Virchows Archiv
Maria J. Ferreira, A. Luís, Márcia Vieira‐Coimbra, Pedro Costa‐Pinheiro, Luís Antunes, Paula C. Dias, Francisco S. N. Lobo, Jorge Oliveira, Céline S. Gonçalves, Bruno M. Costa, Rui Henrique, Cármen Jerónimo,
Increasing detection of small renal masses by imaging techniques entails the need for accurate discrimination between benign and malignant renal cell tumors (RCTs) as well as among malignant RCTs, owing to differential risk of progression through metastization. Although histone methylation has been implicated in renal tumorigenesis, its potential as biomarker for renal cell carcinoma (RCC) progression remains largely unexplored. Thus, we aimed to characterize the differential expression of histone ...
Tópico(s): Epigenetics and DNA Methylation
2017 - Landes Bioscience | Epigenetics
Nuno Videira, Paula Antunes, Rui Santos, Gonçalo Lobo,
Abstract The recent reform of the European water policy recognizes the importance of developing effective mechanisms to support public and stakeholder participation in river basin decision‐making processes. This paper critically reviews the evaluation processes of different types of water related project in five European countries (Portugal, Greece, The Netherlands, the United Kingdom and Spain), with respect to participatory criteria. The horizontal comparison of these cases accounted for criteria ...
Tópico(s): Public Policy and Administration Research
2006 - Wiley | European Environment
A. Luís, Márcia Vieira‐Coimbra, Filipa Quintela Vieira, Pedro Costa‐Pinheiro, Rui Silva-Santos, Paula C. Dias, Luís Antunes, Francisco S. N. Lobo, Jorge Oliveira, Céline S. Gonçalves, Bruno M. Costa, Rui Henrique, Cármen Jerónimo,
Renal cell tumors (RCTs) are the most lethal of the common urological cancers. The widespread use of imaging entailed an increased detection of small renal masses, emphasizing the need for accurate distinction between benign and malignant RCTs, which is critical for adequate therapeutic management. Histone methylation has been implicated in renal tumorigenesis, but its potential clinical value as RCT biomarker remains mostly unexplored. Hence, the main goal of this study was to identify differentially ...
Tópico(s): Epigenetics and DNA Methylation
2015 - Landes Bioscience | Epigenetics
Alexandra M. M. Antunes, Vasco D. B. Bonifácio, Susana Nascimento, Ana M. Lobo, Paula S. Branco, Sundaresan Prabhakar,
Abstract The palladium(II)-promoted reaction of a variety of olefins and bromamine-T provided N-tosyl-2-substituted aziridines under mild conditions. Olefins bearing chiral appendages gave only a poor to modest diastereoselectivity. Appropriate deuterated olefins were selected to study the stereochemistry of the reaction. A Pd(IV) intermediate is proposed as the aziridinating species.
Tópico(s): Sulfur-Based Synthesis Techniques
2007 - Elsevier BV | Tetrahedron
Helena Estevão‐Pereira, João Lobo, Sofia Salta, Isabel Amorim, Paula Lopes, Mariana Cantante, Berta Reis, Luís Antunes, Fernando Castro, Susana Palma de Sousa, Céline S. Gonçalves, Bruno M. Costa, Rui Henrique, Cármen Jerónimo,
Abstract Background Breast cancer (BrC) remains the leading cause of cancer-related death in women, mainly due to recurrent and/or metastatic events, entailing the need for biomarkers predictive of progression to advanced disease. MicroRNAs hold promise as noninvasive cancer biomarkers due to their inherent stability and resilience in tissues and bodily fluids. There is increasing evidence that specific microRNAs play a functional role at different steps of the metastatic cascade, behaving as signaling ...
Tópico(s): Circular RNAs in diseases
2019 - BioMed Central | Journal of Translational Medicine
João Lobo, Ana Laura Costa, Mariana Cantante, Rita de Cássia Avellaneda Guimarães, Paula Lopes, Luís Antunes, Isaac Braga, Jorge Oliveira, Mattia Pelizzola, Rui Henrique, Cármen Jerónimo,
Covalent RNA modifications, such as N-6-methyladenosine (m6A), have been associated with various biological processes, but their role in cancer remains largely unexplored. m6A dynamics depends on specific enzymes whose deregulation may also impact in tumorigenesis. Herein, we assessed the differential abundance of m6A, its writer VIRMA and its reader YTHDF3, in testicular germ cell tumors (TGCTs), looking for clinicopathological correlates. In silico analysis of TCGA data disclosed altered expression ...
Tópico(s): HVDC Systems and Fault Protection
2019 - BioMed Central | Journal of Translational Medicine
Isabel Amorim, João Lobo, Mário Fontes-Sousa, Helena Estevão‐Pereira, Sofia Salta, Paula Lopes, Nuno Coimbra, Luís Antunes, Susana Palma de Sousa, Rui Henrique, Cármen Jerónimo,
Breast cancer (BrC) is the most frequent malignancy and the leading cause of cancer death among women worldwide. Approximately 70% of BrC are classified as luminal-like subtype, expressing the estrogen receptor. One of the most common and effective adjuvant therapies for this BrC subtype is endocrine therapy. However, its effectiveness is limited, with relapse occurring in up to 40% of patients. Because microRNAs have been associated with several mechanisms underlying endocrine resistance and sensitivity, ...
Tópico(s): Cancer Cells and Metastasis
2019 - Frontiers Media | Frontiers in Genetics
Alexandra M. M. Antunes, Susana J. L. Marto, Paula S. Branco, Sundaresan Prabhakar, Ana M. Lobo,
The palladium(II)-promoted reaction of a variety of olefins and bromamine T, as the nitrogen atom transfer reagent, provided N-tosyl-2-substituted aziridines under mild conditions.
Tópico(s): Sulfur-Based Synthesis Techniques
2001 - Royal Society of Chemistry | Chemical Communications
Produção Nacional
Revisado por pares
Simone M. Palmeira, Paula Regina Pereira Silva, Juliana Shimara Pires Ferrão, Aliny Antunes Barbosa Lobo Ladd, M.L. Dagli, César Koppe Grisólia, Francisco Javier Hernandez‐Blazquez,
Pequi ( Caryocar brasiliense Camb.), a fruit from Brazil’s central region, was evaluated for its chemopreventive effects on preneoplastic liver lesions induced by the carcinogen diethylnitrosamine (DEN) in mice. BALB/c mice, 14 days of age, received an intraperitoneal injection at 10 µg/g of DEN. The mice received either of two doses of pequi oil (100 or 400 mg/kg) daily from the age of 30 days and were killed at the age of 189 days. Stereological parameters, including the volume density ( V v ) and the ...
Tópico(s): Carcinogens and Genotoxicity Assessment
2015 - Lippincott Williams & Wilkins | European Journal of Cancer Prevention
João Lobo, Sara Petronilho, Amy Hanlon Newell, Julia Coach, Greg Harlow, Andréia Cruz, Paula Lopes, Luís Antunes, Isaac Bai, Espen J. Walker, Rui Henrique,
Breast cancer is a heterogeneous disease and additional biomarkers for individually predicting patient outcomes are needed. Aberrant membrane E-cadherin immunoexpression has been demonstrated in lobular breast cancer. Also, E-cadherin nuclear staining has been reported, associating with prognosis in various tumors. Here, we explore whether membrane or nuclear staining of E-cadherin has the potential to dictate prognosis of patients with lobular breast cancer. We selected a cohort of 285 consecutively ...
Tópico(s): Cancer Cells and Metastasis
2019 - Elsevier BV | Modern Pathology
Ana Laura Costa, Catarina Moreira-Barbosa, João Lobo, Bárbara Vilela-Salgueiro, Mariana Cantante, Rita de Cássia Avellaneda Guimarães, Paula Lopes, Isaac Braga, Jorge Oliveira, Luís Antunes, Rui Henrique, Cármen Jerónimo,
Aim: Assess differential patterns of selected five genes' promoter methylation among testicular germ cell tumors (TGCT) subtypes. Materials & methods: CRIPTO, HOXA9, MGMT, RASSF1A and SCGB3A1 promoter methylation levels were evaluated by quantitative methylation-specific PCR in 161 TGCT and 16 controls. Associations between clinicopathological parameters and promoter methylation levels were assessed, and receiver operating characteristics curve analysis was performed. Results: Promoter methylation ...
Tópico(s): Urologic and reproductive health conditions
2018 - Future Medicine | Epigenomics
João Lobo, Ana Laura Costa, Bárbara Vilela-Salgueiro, Ângelo Rodrigues, Rita de Cássia Avellaneda Guimarães, Mariana Cantante, Paula Lopes, Luís Antunes, Cármen Jerónimo, Rui Henrique,
Testicular germ cell tumors (TGCTs) are strikingly heterogeneous, reflecting a complex tumor model, posing serious challenges for pathologists. Accurate classification and staging, according to most recent systems, is fundamental. We aimed to revise a series of consecutively diagnosed TGCTs (2005–2016) in light of the new World Health Organization (WHO) classification and American Joint Committee on Cancer (AJCC) staging systems, discussing dilemmas imposed to pathologists. All 164 patients' clinical ...
Tópico(s): Testicular diseases and treatments
2018 - Elsevier BV | Human Pathology
I. Guerreiro, Daniela Barros‐Silva, Paula Lopes, Mariana Cantante, Ana Luísa Cunha, João Lobo, Luís Antunes, Ana Rodrigues, Marta Soares, Rui Henrique, Cármen Jerónimo,
Lung cancer (LC) cells frequently express high levels of programmed death-ligand 1 (PD-L1). Although these levels grossly correlate with the likelihood of response to specific checkpoint inhibitors, the response prediction is rather imperfect, and more accurate predictive biomarkers are mandatory. We examined the methylation profile of RAD51B (RAD51Bme) as a candidate predictive biomarker for anti-PD-1 therapy efficacy in non-small cell lung cancer (NSCLC), correlating with patients' outcome. PD-L1 ...
Tópico(s): Lung Cancer Research Studies
2020 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Produção Nacional
Ângela Beatriz de Carvalho Faria,
... e <em>As mulheres na ficção de António Lobo Antunes: (in)variantes do feminino</em>, de Ana Paula Arnaut, pretende-se analisar o romance <em>Não ... and <em>As mulheres na ficção de António Lobo Antunes</em>: (in) variantes do feminino, by Ana Paula Arnaut, we intent to analyze the romance <em>Não é meia noite quem quer</em>, written by António Lobo Antunes, focusing on the following issues: a) How the “ ...
Tópico(s): Literature, Culture, and Criticism
2014 - | Revista do Centro de Estudos Portugueses
Giorgos Kallis, Nuno Videira, Paula Antunes, Ângela Guimãraes Pereira, Clive L. Spash, Harry Coccossis, Serafín Corral Quintana, Leandro del Moral Ituarte, Dionisia Hatzilacou, Gonçalo Lobo, Alexandra Mexa, Pilar Paneque, Belén Pedregal Mateos, Rui Santos,
The Water Framework Directive institutionalises participatory processes in river basin planning across the European Union. This paper reports on three case studies from southern Europe where conflicts over water exist. In each a different method for participation was experimentally employed: scenario workshops, mediated modelling, and social multicriteria evaluation. Scenario workshops and mediated modelling proved well suited to the early stages of a planning process (problem solving and identification ...
Tópico(s): Policy Transfer and Learning
2006 - SAGE Publishing | Environment and Planning C Government and Policy
Paula S. Branco, Alexandra M. M. Antunes, M. Matilde Marques, M. Paul Chiarelli, Ana M. Lobo, Sundaresan Prabhakar,
A new synthetic pathway for the formation of deoxyguanosine−monoarylamine adducts is described, involving the generation and use of arylnitrenes as electrophilic synthons. Photolysis of aryl azides, the most common method for generating arylnitrenes, was tested in the presence of 2'-deoxyguanosine. N-(2'-Deoxyguanosin-8-yl)monoarylamine (dG-C8-Ar) adducts were obtained, but the yields were typically low. Deoxygenation of nitro- and nitrosoarenes by triethyl phosphite in the presence of 2'-deoxyguanosine ...
Tópico(s): Chemical Reactions and Isotopes
1999 - American Chemical Society | Chemical Research in Toxicology
Produção Nacional
Revisado por pares
<p>O romance de António Lobo Antunes, <em>Comissão das lágrimas,</em> publicado em 2011, traz testemunhos da violência no contexto pós-independência de Angola. Desse modo, estudamos, neste romance, como a configuração da escrita de caráter testemunhal potencializa a refiguração de identidades, tanto individuais quanto coletiva, após experiências traumáticas. Como aporte teórico, utilizamos autores como Paul Ricoeur, Beatriz Sarlo, Seligman-Silva, Bakhtin, bem como diversas contribuições ...
Tópico(s): Literature, Culture, and Criticism
2016 - UNIVERSIDADE FEDERAL DA BAHIA | Estudos Linguísticos e Literários
Produção Nacional
Revisado por pares
The present article is centered in the analytical reading of some chronicles published in the First Book of Chronicles (1998) and the novel Sôbolos rios que vão (2010), by António Lobo Antunes. This thesis shows how time, the memory, childhood and their respective events, as apparently autobiographical aspects are linked to the texture of some chronic and some novel. In fact, we can read in fiction several fictional possibilities and biographical. Structural elements of the Portuguese writer António ...
Tópico(s): History, Culture, and Society
2013 - UNIVERSIDADE FEDERAL DE SANTA CATARINA | Anuário de Literatura
Mário Fontes-Sousa, João Lobo, Silvana Lobo, Sofia Salta, María Galli de Amorim, Paula Lopes, Luís Antunes, Susana Palma de Sousa, Rui Henrique, Cármen Jerónimo,
Breast cancer (BC) is a major health concern and better understanding of its biology might improve treatment decisions and patient outcomes. Histone3 Lysine27 tri-methylation (H3K27me3) is a post-translational histone modification frequently associated with altered gene expression. In BC patients, lower H3K27me3 expression has been associated with worse prognosis. We assessed H3K27me3 immunoexpression with digital imaging software assistance, in a cohort of luminal-like BC patients with long-term ...
Tópico(s): Advanced Breast Cancer Therapies
2020 - BioMed Central | Molecular Medicine
Produção Nacional
Thaís Flecher Barbosa, Danielle Secco, Raquel S. Peixoto, Alexandre Soares Rosado, Flávia Lima do Carmo, Hugo Emiliano de Jesus, Leandro Araújo Lobo, L. Caetano M. Antunes, Karla Rodrigues Miranda, Geraldo Renato de Paula, Regina Maria Cavalcanti Pilotto Domingues,
Clostridium difficile is a nosocomial enteric pathogen, considered the main etiological agent of antibiotic-associated diarrhea in hospitals. C. difficile is resistant to several antimicrobial agents used in empiric treatment protocols, which confers selective advantages to this species as compared with other members of the intestinal microbiota. The aim of this study was to evaluate and identify possible alterations of the intestinal microbiota population resulting from the use of antimicrobials ...
Tópico(s): Microscopic Colitis
2017 - Scientific Research Publishing | Advances in Microbiology
Adriana Alves de Paula Martins,
Abstract: Bearing in mind that the colonial experience decisively influenced the Anglophone and the Lusophone worlds, it is important to consider the literary production of writers from different traditions from a comparative perspective. Their books not only problematize cultural and power structures, but also examine the implications of this process for the construction and transformation of individual and collective identities. In this paper, I propose to compare two books: Os cus de Judas (1979) ...
Tópico(s): Cultural, Media, and Literary Studies
2017 - | Portuguese Literary and Cultural Studies
Tópico(s): Memory, Trauma, and Testimony
2018 - Fundacao Calouste Gulbenkian | Colóquio. Letras
Resenha: ANTUNES, Antônio Lobo. O Arquipélago da Insônia. Lisboa: Dom Quixote, 2008. 263p.
Tópico(s): Urban Development and Societal Issues
2010 - | Revista do Centro de Estudos Portugueses
Produção Nacional
Revisado por pares
... nesse discurso, representando o seu rigor comunicativo. António Lobo Antunes fornece já no primeiro romance de sua vida, uma escrita psicológica e quase autobiográfica, quando muitas informações ficcionais se confundem com a realidade vivenciada pelo autor. Maria Alzira Seixo, Ana Paula Arnaut, Stuart Hall, Zygmunt Bauman entre outros teóricos ...
Tópico(s): Cultural, Media, and Literary Studies
2021 - UNIVERSIDADE ESTADUAL DE LONDRINA | Semina Ciências Sociais e Humanas
I. Guerreiro, Daniela Barros‐Silva, Paula Lopes, Ana Luísa Cunha, João Lobo, Luís Antunes, Ana Rodrigues, Marta Soares, Rui Henrique, Cármen Jerónimo,
e15235 Background: Lung cancer (LC) cells frequently express high levels of programmed death-ligand 1 (PD-L1). Although these levels grossly correlate with likelihood of response to specific checkpoint inhibitors, prediction of response is rather imperfect and, thus, more accurate predictive biomarkers are mandatory. We examined the methylation profile of RAD51B, a DNA-repair gene, as candidate predictive biomarker for efficacy of anti-PD-1 therapy in patients with non-small cell lung cancer (NSCLC), ...
Tópico(s): Epigenetics and DNA Methylation
2020 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
James Glasbey, Omar M. Omar, Dmitri Nepogodiev, Ana Minaya‐Bravo, Brittany Bankhead-Kendall, Marco Fiore, Kaori Futaba, Alodia Gabre‐Kidan, Rohan R Gujjuri, Arda Işık, Haytham M.A. Kaafarani, Sivesh K. Kamarajah, Elizabeth Li, Markus Löffler, Kenneth A McLean, Oumaima Outani, Faustin Ntirenganya, Sohei Satoi, Richard Shaw, Joana F F Simoes, Grant D. Stewart, Stephen Tabiri, Isobel M Trout, Aneel Bhangu, James Glasbey, Omar M. Omar, Aneel Bhangu, Kwabena Siaw-Acheampong, Ruth Benson, Edward Bywater, Daoud Chaudhry, Brett E Dawson, Jonathan P Evans, James Glasbey, Rohan R Gujjuri, Emily Heritage, Conor S Jones, Sivesh K. Kamarajah, Chetan Khatri, Rachel A Khaw, James M Keatley, Andrew T. Knight, Samuel Lawday, Elizabeth Li, Harvinder Mann, Ella J Marson, Kenneth A McLean, S McKay, Emily Mills, Dmitri Nepogodiev, Gianluca Pellino, Maria Picciochi, Elliott H Taylor, Abhinav Tiwari, Joana F F Simoes, Isobel M Trout, Mary L Venn, Richard Wilkin, Aneel Bhangu, James Glasbey, Neil Smart, Ana Minaya‐Bravo, Jonathan P Evans, Gaetano Gallo, Susan Moug, Francesco Pata, Peter Pockney, Salomone Di Saverio, Abigail Vallance, Dale Vimalchandran, Ewen A. Griffiths, Sivesh K. Kamarajah, Richard Evans, Philip Townend, Keith Roberts, S McKay, John Isaac, Sohei Satoi, John Edwards, Aman S. Coonar, Adrian Marchbank, Edward Caruana, Georgia R. Layton, Akshay J. Patel, Alessandro Brunelli, Samuel Ford, Anant Desai, Alessandro Gronchi, Marco Fiore, Max Almond, Fabio Tirotta, Sinziana Dumitra, Angelos G. Kolias, Stephen J. Price, Daniel M. Fountain, Michael D. Jenkinson, Peter J. Hutchinson, Hani J. Marcus, Rory J. Piper, Laura Lippa, Franco Servadei, Ignatius Esene, Christian F. Freyschlag, Iuri Santana Neville, Gail Rosseau, Karl Schaller, Andreas K. Demetriades, Faith C. Robertson, Alexander Alamri, Richard Shaw, Andrew Schache, Stuart C. Winter, Michael Ho, Paul Nankivell, Juan Rey Biel, Martin Batstone, Ian Ganly, Raghavan Vidya, Alex Wilkins, Jagdeep Singh, Dinesh Thekinkattil, Sudha Sundar, Christina Fotopoulou, Elaine Leung, Tabassum Khan, Luis Chiva, Jalid Sehouli, Anna Fagotti, Paul A. Cohen, Murat Gutelkin, Rahel Ghebre, Thomas O. Konney, René Pareja, R.E. Bristow, Sean C. Dowdy, Shylasree T S Rajkumar, Joe Ng, Keiiji Fujiwara, Grant D. Stewart, Benjamin W. Lamb, Krishna Narahari, Alan McNeill, Alexandra J. Colquhoun, John McGrath, Steve Bromage, Ravi Barod, Veeru Kasivisvanathan, Tobias Klatte, Joana F F Simoes, Tom Abbott, Sadi A. Abukhalaf, Michel Adamina, Adesoji Ademuyiwa, Arnav Agarwal, Murat Akkulak, Ehab Alameer, Derek Alderson, Felix Alakaloko, Markus Albertsmeiers, Osaid Alser, Muhammad Alshaar, Sattar Alshryda, Alexis Arnaud, Knut Magne Augestad, Faris Ayasra, José Azevedo, Brittany Bankhead-Kendall, Emma Barlow, David Beard, Ruth Benson, Ruth Blanco‐Colino, Amanpreet Brar, Ana Minaya‐Bravo, Kerry Breen, Chris Bretherton, Igor Lima Buarque, Josh Burke, Edward Caruana, Mohamad K. Abou Chaar, Sohini Chakrabortee, Peter Christensen, Daniel Cox, Moisés Cukier, Miguel F Cunha, Giana H. Davidson, Anant Desai, Salomone Di Saverio, Thomas M Drake, John Edwards, Muhammed Elhadi, Sameh Hany Emile, Shebani Farik, Marco Fiore, J.E.F. Fitzgerald, Samuel Ford, Tatiana Garmanova, Gaetano Gallo, Dhruva Ghosh, Gustavo Mendonça Ataíde Gomes, Gustavo Grecinos, Ewen A. Griffiths, Madalegna Gründl, Constantine Halkias, Ewen M. Harrison, Intisar Hisham, Peter Hutchinson, Shelley Hwang, Arda Işık, Michael D. Jenkinson, Pascal Jonker, Haytham M.A. Kaafarani, Debby Keller, Angelos G. Kolias, Schelto Kruijff, Ismaïl Lawani, Hans Lederhuber, Sezai Leventoğlu, Andrey Litvin, Andrew P. Loehrer, Markus Löffler, Maria Aguilera Lorena, María Marta Modolo, Piotr Major, Janet Martin, Hassan Mashbari, Dennis Mazingi, Symeon Metallidis, Ana Minaya‐Bravo, Helen Mohan, Rachel Moore, David Moszkowicz, Susan Moug, Joshua S Ng-Kamstra, Mayaba Maimbo, Ionuţ Negoi, Milagros Niquen-Jimenez, Faustin Ntirenganya, Maricarmen Olivos, Salah Eddine Oussama Kacimi, Oumaima Outani, Marie Dione Parreno-Sacdalanm, Francesco Pata, C. Perez, Thomas Pinkney, Willemijn Y. van der Plas, Peter Pockney, Ahmad Uzair Qureshi, Dejan Radenković, Antonio Ramos‐De la Medina, Keith Roberts, April Camilla Roslani, Martin Rutegård, Juan José Segura‐Sampedro, Irène Santos, Sohei Satoi, Raza Sayyed, Andrew Schache, Andreas A. Schnitzbauer, Justina O. Seyi‐Olajide, Neil Sharma, Richard Shaw, Sebastian Shu, Kjetil Søreide, Antonino Spinelli, Grant D. Stewart, Malin Sund, Sudha Sundar, Stephen Tabiri, Philip Townend, Georgios Tsoulfas, Gabriëlle H. van Ramshorst, Raghavan Vidya, Dale Vimalachandran, Oliver Warren, Duane Wedderburn, Naomi Wright, C Allemand, L Boccalatte, Marcelo Figari, Martin Lamm, J Larrañaga, Claudia Marchitelli, Florencia Noll, Diego Odetto, M Perrotta, J Saadi, L Zamora, C Alurralde, E L Caram, D Eskinazi, Juan Pablo Camargo Mendoza, M Usandivaras, R Badra, A Esteban, J S García, Pablo García,
Abstract Background Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. Methods This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. ...
Oxford University Press
James Glasbey, Dmitri Nepogodiev, Joana Simões, Omar M. Omar, Elizabeth Li, Mary L Venn, PGDME, Mohamad K. Abou Chaar, V Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P Evans, Marco Fiore, Jose Flavio Videria, Samuel Ford, Ian Ganly, Ewen A. Griffiths, Rohan R Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya‐Bravo, S McKay, Helen Mohan, Keith Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel Bhangu, James C Glasbey, Dmitri Nepogodiev, Joana F F Simoes, Omar M. Omar, Elizabeth Li, Mary L Venn, Mohamad K. Abou Chaar, V Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P Evans, Marco Fiore, Jose Flavio Videria, Samuel Ford, Ian Ganyli, Ewen A. Griffiths, Rohan R Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya‐Bravo, S McKay, Helen Mohan, Keith Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel Bhangu, James C Glasbey, Omar M. Omar, Aneel Bhangu, Kwabena Siaw-Acheampong, Ruth Benson, Edward Bywater, Daoud Chaudhry, Brett E Dawson, Jonathan P Evans, James C Glasbey, Rohan R Gujjuri, Emily Heritage, Conor S Jones, Sivesh K. Kamarajah, Chetan Khatri, Rachel A Khaw, James M Keatley, Andrew T. Knight, Samuel Lawday, Elizabeth Li, Harvinder Mann, Ella J Marson, Kenneth A McLean, S McKay, Emily Mills, Dmitri Nepogodiev, Gianluca Pellino, Maria Picciochi, Elliott H Taylor, Abhinav Tiwari, Joana F F Simoes, Isobel M Trout, Mary L Venn, Richard Wilkin, Aneel Bhangu, James C Glasbey, Neil Smart, Ana Minaya‐Bravo, Jonathan P Evans, Gaetano Gallo, Susan Moug, Francesco Pata, Peter Pockney, Salomone Di Saverio, Abigail Vallance, Dale Vimalchandran, Ewen A. Griffiths, Sivesh K. Kamarajah, Richard Evans, Philip Townend, Keith Roberts, S McKay, John Isaac, Sohei Satoi, John Edwards, Aman S. Coonar, Adrian Marchbank, Edward Caruana, Georgia R. Layton, Akshay J. Patel, Alessandro Brunelli, Samuel Ford, Anant Desai, Alessandro Gronchi, Marco Fiore, Max Almond, Fabio Tirotta, Sinziana Dumitra, Angelos G. Kolias, Stephen J. Price, Daniel M. Fountain, Michael D. Jenkinson, Peter Hutchinson, Hani J. Marcus, Rory J. Piper, Laura Lippa, Franco Servadei, Ignatius Esene, Christian F. Freyschlag, Iuri Santana Neville, Gail Rosseau, Karl Schaller, Andreas K. Demetriades, Faith C. Robertson, Alexander Alamri, Richard Shaw, Andrew Schache, Stuart C. Winter, Michael Ho, Paul Nankivell, Juan Rey Biel, Martin Batstone, Ian Ganly, Raghavan Vidya, Alex Wilkins, Jagdeep Singh, Dinesh Thekinkattil, Sudha Sundar, Christina Fotopoulou, Elaine Leung, Tabassum Khan, Luis Chiva, Jalid Sehouli, Anna Fagotti, Paul A. Cohen, Murat Gutelkin, Rahel Ghebre, Thomas O. Konney, René Pareja, R.E. Bristow, Sean C. Dowdy, TS Shylasree, Rajkumar Kottayasamy Seenivasagam, Joe Ng, Keiiji Fujiwara, Grant D. Stewart, Benjamin W. Lamb, Krishna Narahari, Alan McNeill, Alexandra J. Colquhoun, John McGrath, Steve Bromage, Ravi Barod, Veeru Kasivisvanathan, Tobias Klatte, Joana F F Simoes, Tom Abbott, Sadi A. Abukhalaf, Michel Adamina, Adesoji Ademuyiwa, Arnav Agarwal, Murat Akkulak, Ehab Alameer, Derek Alderson, Felix Alakaloko, Markus Albertsmeiers, Osaid Alser, Muhammad Alshaar, Sattar Alshryda, Alexis Arnaud, Knut Magne Augestad, Faris Ayasra, José Azevedo, Brittany Bankhead-Kendall, Emma Barlow, David Beard, Ruth Benson, Ruth Blanco‐Colino, Amanpreet Brar, Ana Minaya‐Bravo, Kerry Breen, Chris Bretherton, Igor Lima Buarque, Josh Burke, Edward Caruana, Mohamad K. Abou Chaar, Sohini Chakrabortee, Peter Christensen, Daniel Cox, Moisés Cukier, Miguel F Cunha, Giana H. Davidson, Anant Desai, Salomone Di Saverio, Thomas M Drake, John Edwards, Muhammed Elhadi, Sameh Hany Emile, Shebani Farik, Marco Fiore, J.E.F. Fitzgerald, Samuel Ford, Tatiana Garmanova, Gaetano Gallo, Dhruva Ghosh, Gustavo Mendonça Ataíde Gomes, Gustavo Grecinos, Ewen A. Griffiths, Madalegna Gründl, Constantine Halkias, Ewen M. Harrison, Intisar Hisham, Peter Hutchinson, Shelley Hwang, Arda Işık, Michael D. Jenkinson, Pascal Jonker, Haytham M.A. Kaafarani, Debby Keller, Angelos G. Kolias, Schelto Kruijff, Ismaïl Lawani, Hans Lederhuber, Sezai Leventoğlu, Andrey Litvin, Andrew P. Loehrer, Markus Löffler, Maria Aguilera Lorena, María Marta Modolo, Piotr Major, Janet Martin, Hassan Mashbari, Dennis Mazingi, Symeon Metallidis, Ana Minaya‐Bravo, Helen Mohan, Rachel Moore, David Moszkowicz, Susan Moug, Joshua S Ng-Kamstra, Mayaba Maimbo, Ionuţ Negoi, Milagros Niquen-Jimenez, Faustin Ntirenganya, Maricarmen Olivos, Salah Eddine Oussama Kacimi, Oumaima Outani, Marie Dione Parreno-Sacdalanm, Francesco Pata, C. Perez, Thomas Pinkney, Willemijn Y. van der Plas, Peter Pockney, Ahmad Uzair Qureshi, Dejan Radenković, Antonio Ramos‐De la Medina, Keith Roberts, April Camilla Roslani, Martin Rutegård, Juan José Segura‐Sampedro, Irène Santos,
PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without ...
Lippincott Williams & Wilkins
James Glasbey, Adesoji Ademuyiwa, Adewale Adisa, Ehab Alameer, Alexis Arnaud, Faris Ayasra, José Azevedo, Ana Minaya‐Bravo, Ainhoa Costas‐Chavarri, John Edwards, Muhammed Elhadi, Marco Fiore, Christina Fotopoulou, Gaetano Gallo, Dhruva Ghosh, Ewen A. Griffiths, Ewen M. Harrison, Peter Hutchinson, Ismaïl Lawani, Samuel Lawday, Hans Lederhuber, Sezai Leventoğlu, Elizabeth Li, Gustavo Mendonça Ataíde Gomes, Harvinder Mann, Ella J Marson, Janet Martin, Dennis Mazingi, Kenneth A McLean, María Marta Modolo, Rachel Moore, Dion Morton, Faustin Ntirenganya, Francesco Pata, Maria Picciochi, Peter Pockney, Antonio Ramos‐De la Medina, Keith Roberts, April Camilla Roslani, Rajkumar Kottayasamy Seenivasagam, Richard Shaw, Joana Filipa Ferreira Simões, Neil Smart, Grant D. Stewart, Richard Sullivan, Sudha Sundar, Stephen Tabiri, Elliott H Taylor, Raghavan Vidya, Dmitri Nepogodiev, Aneel Bhangu, James C Glasbey, Kenneth A McLean, Dmitri Nepogodiev, Ewen M. Harrison, Aneel Bhangu, Dmitri Nepogodiev, Kwabena Siaw-Acheampong, Ruth Benson, Edward Bywater, Daoud Chaudhry, Brett E Dawson, Jonathan P Evans, James C Glasbey, Rohan R Gujjuri, Emily Heritage, Conor Jones, Sivesh K. Kamarajah, Chetan Khatri, Rachel A Khaw, James M Keatley, Andrew T. Knight, Samuel Lawday, Elizabeth Li, Harvinder Mann, Ella J Marson, Kenneth A McLean, S McKay, Emily Mills, Gianluca Pellino, Maria Picciochi, Elliott H Taylor, Abhinav Tiwari, Joana F F Simoes, Isobel M Trout, Mary L Venn, Richard Wilkin, Aneel Bhangu, James C Glasbey, Neil Smart, Ana Minaya‐Bravo, Jonathan P Evans, Gaetano Gallo, Susan Moug, Francesco Pata, Peter Pockney, Salomone Di Saverio, Abigail Vallance, Dale Vimalchandran, Ewen A. Griffiths, Sivesh K. Kamarajah, Richard Evans, Philip Townend, Keith Roberts, S McKay, John Isaac, Sohei Satoi, John Edwards, Aman S. Coonar, Adrian Marchbank, Edward Caruana, Georgia R. Layton, Akshay J. Patel, Alessandro Brunelli, Samuel Ford, Anant Desai, Alessandro Gronchi, Marco Fiore, Max Almond, Fabio Tirotta, Sinziana Dumitra, Angelos G. Kolias, Stephen J. Price, Daniel M. Fountain, Michael D. Jenkinson, Peter Hutchinson, Hani J. Marcus, Rory J. Piper, Laura Lippa, Franco Servadei, Ignatius Esene, Christian F. Freyschlag, Iuri Santana Neville, Gail Rosseau, Karl Schaller, Andreas K. Demetriades, Faith C. Robertson, Alexander Alamri, Richard Shaw, Andrew Schache, Stuart C. Winter, Michael Ho, Paul Nankivell, Juan Rey Biel, Martin Batstone, Ian Ganly, Raghavan Vidya, Alex Wilkins, Jagdeep Singh, Dinesh Thekinkattil, Sudha Sundar, Christina Fotopoulou, Elaine Leung, Tabassum Khan, Luis Chiva, Jalid Sehouli, Anna Fagotti, Paul A. Cohen, Murat Gutelkin, Rahel Ghebre, Thomas O. Konney, René Pareja, R.E. Bristow, Sean C. Dowdy, TS Shylasree, Rajkumar Kottayasamy Seenivasagam, Joe Ng, Keiichi Fujiwara, Grant D. Stewart, Benjamin W. Lamb, Krishna Narahari, Alan McNeill, Alexandra J. Colquhoun, John McGrath, Steve Bromage, Ravi Barod, Veeru Kasivisvanathan, Tobias Klatte, Joana F F Simoes, Tom Abbott, Sadi A. Abukhalaf, Michel Adamina, Adesoji Ademuyiwa, Arnav Agarwal, Murat Akkulak, Ehab Alameer, Derek Alderson, Felix Alakaloko, Markus Albertsmeier, Osaid Alser, Muhammad Alshaar, Sattar Alshryda, Alexis Arnaud, Knut Magne Augestad, Faris Ayasra, José Azevedo, Brittany Bankhead-Kendall, Emma Barlow, David Beard, Ruth Benson, Ruth Blanco‐Colino, Amanpreet Brar, Ana Minaya‐Bravo, Kerry Breen, Chris Bretherton, Igor Lima Buarque, Josh Burke, Edward Caruana, Mohamad K. Abou Chaar, Sohini Chakrabortee, Peter Christensen, Daniel Cox, Moisés Cukier, Miguel F Cunha, Giana H. Davidson, Anant Desai, Salomone Di Saverio, Thomas M Drake, John Edwards, Muhammed Elhadi, Sameh Hany Emile, Shebani Farik, Marco Fiore, J.E.F. Fitzgerald, Samuel Ford, Tatiana Garmanova, Gaetano Gallo, Dhruva Ghosh, Gustavo Mendonça Ataíde Gomes, Gustavo Grecinos, Ewen A. Griffiths, Magdalena Gruendl, Constantine Halkias, Ewen M. Harrison, Intisar Hisham, Peter Hutchinson, Shelley Hwang, Arda Işık, Michael D. Jenkinson, Pascal Jonker, Haytham M.A. Kaafarani, Debby Keller, Angelos G. Kolias, Schelto Kruijff, Ismaïl Lawani, Hans Lederhuber, Sezai Leventoğlu, Andrey Litvin, Andrew P. Loehrer, Markus Löffler, Maria Aguilera Lorena, María Marta Modolo, Piotr Major, Janet Martin, Hassan Mashbari, Dennis Mazingi, Symeon Metallidis, Ana Minaya‐Bravo, Helen Mohan, Rachel Moore, David Moszkowicz, Susan Moug, Joshua S Ng-Kamstra, Mayaba Maimbo, Ionuţ Negoi, Milagros Niquen-Jimenez, Faustin Ntirenganya, Maricarmen Olivos, Salah Eddine Oussama Kacimi, Oumaima Outani, Marie Dione Parreno-Sacdalanm, Francesco Pata, C. Perez, Thomas Pinkney, Willemijn Y. van der Plas, Peter Pockney, Ahmad Uzair Qureshi, Dejan Radenković, Antonio Ramos‐De la Medina, Toby Richards, Keith Roberts, April Camilla Roslani, Martin Rutegård, Juan José Segura‐Sampedro, Irène Santos, Sohei Satoi, Raza Sayyed, Andrew Schache, Andreas A. Schnitzbauer, Justina O. Seyi‐Olajide, Neil Sharma, Catherine A. Shaw, Richard Shaw, Sebastian Shu, Kjetil Søreide, Antonino Spinelli,
BackgroundSurgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery during the COVID-19 pandemic in periods of lockdown versus light restriction.MethodsThis international, prospective, cohort study enrolled 20 006 adult (≥18 years) patients from 466 hospitals in 61 countries with 15 cancer types, who had a decision for curative ...
Elsevier BV
Alexandra M. M. Antunes, Vasco D. B. Bonifácio, Susana Nascimento, Ana M. Lobo, Paula S. Branco, Sundaresan Prabhakar,
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Tópico(s): Sulfur-Based Synthesis Techniques
2007 - Wiley | ChemInform