ALWYN PARKER., DESBOROUGH. H. A. L. FISHER. C. W. C. OMAN., GEORGE MANINGTON., HENRY E. ARMSTRONG., M. DE P. WEBB., ARTHUR E. BEECROFT., JOHN H. ELLISON., Mr. J. REID MOIR., CALLISTHENES, WARREN R. DAWSON, , J. H. JEANS., G. M. B. DOBSON., GEORGE HAMILTON., W. H. OATLEY, , RICHMOND TEMPLE,
... Wool Position Australia's Loan Obligations Sir Otto Niemeyer's Mission The ... Sao Paulo Debt Service Favourable Statement, Meeting Of Rubber Producers, ...
1930 - Gale Group | TDA
Produção Nacional
Revisado por pares
Suzana Assad Kahn, Sílvia Lima Costa, Sharareh Gholamin, Ryan T. Nitta, Luiz Gustavo Dubois, Marie Fève, Maria Zeniou, Paulo Lucas Cerqueira Coelho, Elias A. El-Habr, Josette Cadusseau, Pascale Varlet, Siddhartha S. Mitra, Bertrand Devaux, Marie‐Claude Kilhoffer, Samuel Cheshier, Vivaldo Moura‐Neto, Jacques Haiech, Marie‐Pierre Junier, Hervé Chneiweiss,
... Seine-IBPS, Paris, France Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Brazil Search for more papers ... Neto Vivaldo Moura-Neto Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Brazil Search for more papers ... Seine-IBPS, Paris, France Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Brazil Search for more papers ... Neto Vivaldo Moura-Neto Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Brazil Search for more papers ... Bahia, Salvador-Bahia, Brazil 6Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Brazil 7Laboratoire d'Innovation Thérapeutique, ...
Tópico(s): Cancer Cells and Metastasis
2016 - Springer Nature | EMBO Molecular Medicine
FROM OUR RACING CORRESPONDENT, FROM OUR OWN CORRESPONDENT, FROM OUR BOXING CORRESPONDENT, FROM OUR AERONAUTICAL CORRESPONDENT, FROM OUR CORRESPONDENT, By CALLISTHENES, FROM OUR MUSIC CRITIC, FROM OUR SPECIAL CORRESPONDENT, FROM OUR CHESS CORRESPONDENT, By Sir Arthur Evans, Our Gibraltar Correspondent, FROM OUR MONTEVIDEO CORRESPONDENT, FROM OUR LEAGUE CORRESPONDENT, FROM OUR CITY EDITOR, A correspondent lately in Santiago, From Our Parliamentary Correspondent, FRANCIS W. HIRST, F. W. DYSON, , ARTHUR PINERO, M. A. STUCKEY, From Our Tokyo Correspondent, A correspondent, A correspondent writes, FROM A CORRESPONDENT, H. ARNHOLD., MARGOT OXFORD., A. W. SMALLWOOD, , V. P. GONSALVES., SALTOUN., C. G. HANCOCK, J. H. MACRAE-GIBSON., ALFRED C. DEWAR, , FROM A MILITARY CORRESPONDENT, FROM OUR AGRICULTURAL CORRESPONDENT, FROM OUR KENNEL CORRESPONDENT, PORTLAND, J. A. HALL, W. H. SCOTT,
... Material Prices, City Notes Gold Outflow Stopped The Niemeyer Report On Brazil, Company Meeting Head, Wrightson & Co. ...
1931 - Gale Group | TDA
Produção Nacional
Revisado por pares
José Orlando de Melo, Márcia Aparecida Lodi Campos Melo, Luiz Antônio da Silva Lavradas, Plínio Gabriel Lopes, Ingra Ianne Luiz Ornelas, Paula Lacerda de Barros, Paulo José da Mata Pereira, Paulo Niemeyer Filho,
... first 30 days after intracranial neurosurgical procedure at Paulo Niemeyer State Brain Institute, from September 2013 to February ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2020 - Elsevier BV | Clinical Neurology and Neurosurgery
FROM OUR RACING CORRESPONDENT, FROM OUR RACKETS CORRESPONDENT, FROM OUR HUNTING CORRESPONDENT, FROM OUR RUGBY FOOTBALL, FROM OUR BILLIARDS CORRESPONDENT, FROM OUR SPECIAL CORRESPONDENT, FROM OUR COURSING CORRESPONDENT, FROM OUR OWN CORRESPONDENT, FROM A CORRESPONDENT, FROM OUR CORRESPONDENT, HOWARD, R. C. CULLING CARR, DERMOT MORRAH., HUBERTUS PRINCE LOEWENSTEIN, R. M. RAYNSFORD, JOSIAH C. WEDGWOOD., MOTTISTONE, MISS JOAN REDFERN, Mr. Nelson Dawson, By CALLISTHENES, From a Special Correspondent, FROM OUR LEAGUE CORRESPONDENT, FROM OUR WEATHER CORRESPONDENT, FROM OUR RIVIERA CORRESPONDENT, FROM OUR LABOUR CORRESPONDENT, F. S. GARWOOD, W. G. COCHRAN., By Our Own Correspondent, FROM OUR AERONAUTICAL CORRESPONDENT, FROM OUR CHESS CORRESPONDENT, FROM OUR CIVIL SERVICE CORRESPONDENT, "Some of his Friends", A correspondent, The Rev. Michael Adler,
... Motoring Speed Limit, Finances Of India Sir Otto Niemeyer's Inquiry, Preserving The Avon Gorge Mr. Melville ... Conditions, Oilfields News, Milling Merger, City Of San Paulo Improvements Extension Of Moratorium, Traffic Receipts, Argentine Grain ...
1936 - Gale Group | TDA
Manas Sharma, Aditya Bharatha, Oleh Antonyshyn, Richard I. Aviv, Sean Symons,
... ressonância magnética - relato de casoRafael Alfenas dePaula, Bruno Niemeyer de FreitasRibeiro, Paulo Roberto ValleBahia, Renato Niemeyer de FreitasRibeiro, Laís Balbi deCarvalho2014 | Radiologia Brasileira, Vol. ...
Tópico(s): Genetic Syndromes and Imprinting
2012 - Radiological Society of North America | Radiology
D. CACLAMANOS., WITTENHAM., W.SHAKSPEARE., JAMES LANYON., A. H. CHIFFERIEL., REDCLIFFE N. SALAMAN., CHARLES MALLET., THOMASS ADAMS., HENRY S. SALT., CALLISTHENES, GILBERT COLEBIDGE., ONLOOKER., W. M. CHILDS., GUY FLEETWOOD WILSON., J. H. F.,
... Policy Mr. Lang's Attack On Sir O. Niemeyer. News in Brief. Official Appointments and Notices: Naval ... Passed Arrangement With Distillers Company, Company Results San Paulo Coffee Loss, Oilfields News, Brazilian Markets, Australian Wool ...
1930 - Gale Group | TDA
Produção Nacional
Revisado por pares
Daniel D. Cavalcanti, Jose Antônio Damian Guasti, Mark C. Preul,
... in Brazil. Among his many innovations in neurosurgery, Paulo Niemeyer first described the transventricular amygdalohippocampectomy in 1957 and ...
Tópico(s): History of Medicine Studies
2010 - Lippincott Williams & Wilkins | Neurosurgery
Elza Márcia Targas Yacubian, Ésper A. Cavalheiro,
Paulo Niemeyer Soares was born in Rio de Janeiro on April 14, 1914. He was the son of ... an architect of great masterpieces in Brasília. Dr. Paulo Niemeyer had six children and three foster children. In ... support to pursue his medical profession with enthusiasm. Paulo Niemeyer was graduated from the Faculdade Nacional de Medicina ... place among 270 candidates in a medical contest. Paulo Niemeyer showed great interest in many branches of surgery, ... of the National Academy of Medicine in 1981. Paulo Niemeyer's medical vocation was linked to a painful ...
Tópico(s): Palliative and Oncologic Care
2004 - Wiley | Epilepsia
Produção Nacional
Revisado por pares
Federico Gatto, Luiz Eduardo Wildemberg, Diego Ferone, Mônica R. Gadelha,
... 21941-913, BrazilNeuroendocrine Unit - Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro 20231- ... 21941-913, BrazilNeuroendocrine Unit - Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro 20231- ... and Molecular Genetics Laboratory, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro 20231- ...
Tópico(s): Neuroendocrine Tumor Research Advances
2022 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
Produção Nacional
Revisado por pares
Leonardo Vieira Neto, Ednildo A. Machado, Raúl M. Luque, Giselle Fernandes Taboada, Jorge B Marcondes, Leila Chimelli, Leonardo Pereira Quintella, Paulo Niemeyer, Denise Pires de Carvalho, Rhonda D. Kineman, Mônica R. Gadelha,
Dopamine receptor (DR) and somatostatin receptor subtype expression in pituitary adenomas may predict the response to postsurgical therapies.Our objectives were to assess and compare the mRNA levels of DR1-5 and somatostatin receptors 1-5 in normal pituitaries (NPs), nonfunctioning pituitary adenomas (NFPAs), and somatotropinomas. In addition, we determined whether the level of DR expression correlates with the in vivo response to octreotide-LAR in acromegalic patients.Eight NPs, 30 NFPAs, and 39 somatotropinomas ...
Tópico(s): Growth Hormone and Insulin-like Growth Factors
2009 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
Produção Nacional
Revisado por pares
Giselle Fernandes Taboada, Raúl M. Luque, Leonardo Vieira Neto, Ednildo A. Machado, Bruna C Sbaffi, Romeu Côrtes Domingues, Jorge B Marcondes, Leila Chimelli, Rosita Fontes, Paulo Niemeyer, Denise Pires de Carvalho, Rhonda D. Kineman, Mônica R. Gadelha,
Objective To determine whether the somatostatin receptor subtype (SSTR) expression profile correlates with hormonal and tumor volume responses to postsurgical octreotide long acting repeatable (OCT LAR) treatment. Design and methods Quantitative real-time RT-PCR was used to evaluate the absolute mRNA copy numbers for all five SSTR subtypes in 22 somatotropinomas. Response to OCT LAR was studied by hormone levels (GH and IGF-I) and tumor volume (sella turcica magnetic resonance imaging). Results SSTR5 ...
Tópico(s): Adrenal and Paraganglionic Tumors
2008 - Oxford University Press | European Journal of Endocrinology
Produção Nacional
Revisado por pares
Giovanna Aparecida Balarini Lima, Evelyn de Oliveira Machado, Cintia Marques dos Santos Silva, Paulo Niemeyer Filho, Mônica R. Gadelha,
Tópico(s): Glioma Diagnosis and Treatment
2007 - Springer Science+Business Media | Pituitary
Produção Nacional
Revisado por pares
Giselle Fernandes Taboada, Raúl M. Luque, Wildebranham Bastos, Renata F.C. Guimarães, Jorge B Marcondes, Leila Chimelli, Rosita Fontes, Paulo J P Mata, Paulo Niemeyer Filho, Denise Pires de Carvalho, Rhonda D. Kineman, Mônica R. Gadelha,
Objective : It is believed that the variable effectiveness of somatostatin analogs in post-surgical management of somatotropinomas and non-functioning pituitary adenomas (NFPA) may be due in part to variable expression of somatostatin receptor isoforms (SSTR1–5), within and between pituitary tumor types. Design and methods : Quantitative real-time RT-PCR was used to compare absolute mRNA copy numbers for all five SSTR isoforms in 23 somatotropinomas and 19 NFPA. Results : Somatostatin receptor subtype 5 ...
Tópico(s): Growth Hormone and Insulin-like Growth Factors
2007 - Oxford University Press | European Journal of Endocrinology
Produção Nacional
Revisado por pares
Luiz Eduardo Wildemberg, Leonardo Vieira Neto, Paulo Niemeyer, Emerson L. Gasparetto, Leila Chimelli, Mônica R. Gadelha,
Objective To describe pituitary apoplexy that developed during the course of dengue hemorrhagic fever. Methods We describe the clinical findings, laboratory test results, imaging findings, and clinical course of the study patients. Results Patient 1 was a 40-year-old man who developed clinical signs and symptoms of dengue, which was confirmed by serologic testing. He presented with thrombocytopenia and developed severe headache and vomiting. During hospitalization, acromegaly was suspected because ...
Tópico(s): Retinoids in leukemia and cellular processes
2012 - Elsevier BV | Endocrine Practice
Produção Nacional
Revisado por pares
Inês Donangelo, Heliomar Pereira Marcos, Paula Bruna Araújo, Jorge Marcondes de Souza, Paulo Niemeyer Filho, Mônica R. Gadelha, Leila Chimelli,
Tópico(s): Cancer-related Molecular Pathways
2005 - Springer Science+Business Media | Endocrine Pathology
Produção Nacional
Revisado por pares
Diana Matias, Danilo Predes, Paulo Niemeyer Filho, María Celeste Lopes, José G. Abreu, Flávia Regina Souza Lima, Vivaldo Moura‐Neto,
Glioblastoma, the most aggressive and fatal type of brain tumor, is capable of interacting with brain immune cells such as microglia, which contributes to the growth of these tumors. Various molecules, including growth factors and cytokines, have been identified as regulators of microglia-glioblastoma interaction. Recent studies suggest that the Wnt family of lipoglycoproteins plays an important role, not only in biological events during development, but also in cancer progression, and can be part ...
Tópico(s): MicroRNA in disease regulation
2017 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Produção Nacional
Revisado por pares
Joana Balça-Silva, Diana Matias, Luiz Gustavo Dubois, Brenno Carneiro, Anália do Carmo, Henrique Girão, Fernanda Lima Ferreira, Valéria Pereira Ferrer, Leila Chimelli, Paulo Niemeyer Filho, Hermínio Tão, Olinda Rebelo, Marcos Barbosa, Ana Bela Sarmento‐Ribeiro, María Celeste Lopes, Vivaldo Moura‐Neto,
Glioblastoma (GBM) is the most malignant primary brain tumor, with an average survival rate of 15 months. GBM is highly refractory to therapy, and such unresponsiveness is due, primarily, but not exclusively, to the glioma stem-like cells (GSCs). This subpopulation express stem-like cell markers and is responsible for the heterogeneity of GBM, generating multiple differentiated cell phenotypes. However, how GBMs maintain the balance between stem and non-stem populations is still poorly understood. ...
Tópico(s): Barrier Structure and Function Studies
2017 - Elsevier BV | Translational Oncology
Produção Nacional
Revisado por pares
Felipe Cupertino, João Paulo Niemeyer‐Corbellini, Márcia Ramos‐e‐Silva,
Vitiligo is a chronic common skin disease. The asymptomatic hypopigmented cutaneous lesions are considered by many health care professionals as a cosmetic problem only; however, vitiligo can have a major psychosocial impact on patients' lives. We review some of the factors responsible for this impact, such as the general public's wrong perception of the disease, feelings and emotional responses from patients, how stressful events can act as triggers of the disease, stigmatization experiences suffered ...
Tópico(s): Skin Protection and Aging
2017 - Elsevier BV | Clinics in Dermatology
Produção Nacional
Revisado por pares
Gustavo Moreira Amorim, João Paulo Niemeyer‐Corbellini, Danielle Carvalho Quintella, Tullia Cuzzi, Márcia Ramos‐e‐Silva,
Background: Mycosis fungoides is the most common form of primary cutaneous lymphoma, with an indolent, slowly progressive course and 88% five-year survival rate. The diagnosis is challenging, especially in the early stages, and usually relies on a good clinical-histopathological correlation. Objective: The aim was to establish the clinical and epidemiological profile of patients with early-stage mycosis fungoides. Methods: This was a retrospective cross-sectional observational study with an exploratory ...
Tópico(s): Lymphoma Diagnosis and Treatment
2018 - Elsevier BV | Anais Brasileiros de Dermatologia
Produção Nacional
Revisado por pares
Diana Matias, Luiz Gustavo Dubois, Bruno Pontes, Luciane Rosário, Valéria Pereira Ferrer, Joana Balça-Silva, Anna Carolina Carvalho da Fonseca, Lucy Wanjiku Macharia, Luciana Romão, Tânia Cristina Leite de Sampaio e Spohr, Leila Chimelli, Paulo Niemeyer Filho, María Celeste Lopes, José G. Abreu, Flávia Regina Souza Lima, Vivaldo Moura‐Neto,
Tópico(s): Circular RNAs in diseases
2018 - Springer Science+Business Media | Molecular Neurobiology
Produção Nacional
Revisado por pares
Ximene Antunes, Nina Ventura, Gustavo Bittencourt Camilo, Luiz Eduardo Wildemberg, André Guasti, Paulo José M. Pereira, Aline Helen Silva Camacho, Leila Chimelli, Paulo Niemeyer, Mônica R. Gadelha, Leandro Kasuki,
Tópico(s): Adrenal and Paraganglionic Tumors
2018 - Springer Science+Business Media | Endocrine
Produção Nacional
Revisado por pares
Gustavo Moreira Amorim, João Paulo Niemeyer‐Corbellini, Danielle Carvalho Quintella, Tullia Cuzzi, Márcia Ramos‐e‐Silva,
Hypopigmented mycosis fungoides (hMF) is a rare subtype of mycosis fungoides. The aim of this study was to identify the clinical-epidemiological profile of our patient group and also to provide additional information about treatment responses and prognosis.This is a cross-sectional retrospective observational study, with exploratory analysis. The outcome variables were disease progression and related death.Twenty patients with hMF were selected from a group of 102 patients diagnosed with MF. There ...
Tópico(s): Vascular Tumors and Angiosarcomas
2018 - Wiley | International Journal of Dermatology
Produção Nacional
Revisado por pares
Monique Barreto Santana, Cristiane da Cruz Lamas, Jonathan Athayde, Guilherme Amaral Calvet, Jéssica Pronestino de Lima Moreira, Armando Lorenzo,
... Fialho, the paediatrician at Instituto Nacional do Cérebro Paulo Niemeyer, who helped in the identification of patients for ...
Tópico(s): Viral Infections and Vectors
2019 - Elsevier BV | Clinical Microbiology and Infection
Produção Nacional
Revisado por pares
Bruno Gonçalves, Cássia Righy, Pedro Kurtz,
... admitted to the intensive care unit (ICU) of Paulo Niemeyer State Brain Institute due to severe acute respiratory ...
Tópico(s): Thermal Regulation in Medicine
2020 - Springer Science+Business Media | Neurocritical Care
Produção Nacional
Revisado por pares
Marcos F. DosSantos, Sylvie Devalle, Veronica Aran, Daniela Capra, Natália R. Roque, Juliana de Mattos Coelho‐Aguiar, Tânia Cristina Leite de Sampaio e Spohr, Janice Gonçalves Subilhaga, Cláudia Maria Pereira, Isabella D’Andrea Meira, Paulo Niemeyer Filho, Vivaldo Moura‐Neto,
Recent studies have suggested the neuroinvasive potential of severe acute respiratory coronavirus 2 (SARS-CoV-2). Notably, neuroinvasiveness might be involved in the pathophysiology of coronavirus disease 2019 (COVID-19). Some studies have demonstrated that synapse-connected routes may enable coronaviruses to access the central nervous system (CNS). However, evidence related to the presence of SARS-CoV-2 in the CNS, its direct impact on the CNS, and the contribution to symptoms suffered, remain sparse. ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2020 - Frontiers Media | Frontiers in Neuroanatomy
Produção Nacional
Revisado por pares
Wanjiru Muriithi, Lucy Wanjiku Macharia, Carlos Pilotto Heming, Juliana Lima Echevarria, Atunga Nyachieo, Paulo Niemeyer Filho, Vivaldo Moura‐Neto,
The ATP-binding cassette transporters (ABC transporters) have been intensely studied over the past 50 years for their involvement in the multidrug resistance (MDR) phenotype, especially in cancer. They are frequently overexpressed in both naive and post-treatment tumors, and hinder effective chemotherapy by reducing drug accumulation in cancer cells. In the last decade however, several studies have established that ABC transporters have additional, fundamental roles in tumor biology; there is strong ...
Tópico(s): HIV/AIDS drug development and treatment
2020 - Chinese Anti-Cancer Association | Cancer Biology and Medicine
Produção Nacional
Revisado por pares
Renan Lyra Miranda, Alexandro Guterres, Carlos Henrique de Azeredo Lima, Paulo Niemeyer Filho, Mônica R. Gadelha,
Knowledge of viral load is essential to formulate strategies for antiviral treatment, vaccination, and epidemiological control of COVID-19. Moreover, identification of patients with high viral loads can also be useful to understand risk factors such as age, comorbidities, severity of symptoms and hypoxia, to decide on the need for hospitalization. Several ongoing studies are analyzing viral load in different types of samples and evaluating its relationship with clinical outcomes and viral transmission ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2021 - Elsevier BV | Virus Research
Produção Nacional
Revisado por pares
Lucy Wanjiku Macharia, Wanjiru Muriithi, Carlos Pilotto Heming, Dennis Kirii Nyaga, Veronica Aran, Marianne Mureithi, Valéria Pereira Ferrer, Attilio Pane, Paulo Niemeyer Filho, Vivaldo Moura‐Neto,
Abstract Background Glioblastoma is a fatal brain tumour with a poor patient survival outcome. Hypoxia has been shown to reprogram cells towards a stem cell phenotype associated with self-renewal and drug resistance properties. Activation of hypoxia-inducible factors (HIFs) helps in cellular adaptation mechanisms under hypoxia. Similarly, miRNAs are known to be dysregulated in GBM have been shown to act as critical mediators of the hypoxic response and to regulate key processes involved in tumorigenesis. ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2021 - BioMed Central | BMC Cancer
Produção Nacional
Revisado por pares
Pedro Kurtz, Cássia Righy, Mônica R. Gadelha, Fernando A. Bozza, Patrı́cia T. Bozza, Bruno Gonçalves, Leonardo dos Santos Lourenço Bastos, André M. Vale, Luiza M. Higa, Leda R. Castilho, Fábio L. Monteiro, Nestor Charris, Fernanda Fialho, Ricardo Turon, Alexandro Guterres, Renan Lyra Miranda, Carlos Henrique de Azeredo Lima, Vanessa de, Marco Prazeres, Nina Ventura, Clara H Gaspari, Fabio G. Miranda, Paulo Jose da Mata, Margarida Pêcego, Sheila de Oliveira Garcia Mateos, Maria Esther Lopes, Shirley Lopes de Castilho, Álvaro Maciel Oliveira, Carla Boquimpani, Andréa Rabello, Josiane Lopes, Orlando Conceição Neto, Orlando da Costa Ferreira, Amílcar Tanuri, Paulo Niemeyer Filho, Luiz Amorim,
Background: Convalescent plasma is a potential therapeutic option for critically ill patients with coronavirus disease 19 (COVID-19), yet its efficacy remains to be determined. The aim was to investigate the effects of convalescent plasma (CP) in critically ill patients with COVID-19. Methods: This was a single-center prospective observational study conducted in Rio de Janeiro, Brazil, from March 17th to May 30th, with final follow-up on June 30th. We included 113 laboratory-confirmed COVID-19 patients ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2021 - Frontiers Media | Frontiers in Medicine