Produção Nacional
Revisado por pares
Magda CB Gomes, Joanne Kotsopoulos, Gutemberg Almeida, Maurício Magalhães Costa, Roberto José da Silva Vieira, Firmino de AG Filho, Marcos Bettini Pitombo, Paulo Roberto Falcão Leal, Robert E. Royer, Phil Zhang, Steven A. Narod,
Abstract Background Germline mutations in p53 are associated with the Li-Fraumeni Syndrome which is characterized by childhood cancers, including pediatric adrenal cortical carcinomas and early onset breast cancer. The high incidence of adrenal cortical carcinomas in southern Brazil is mostly attributed to the R337H mutation in TP53 . The relatively high population frequency of this mutation in southern Brazil, along with the clustering of early onset breast cancer in Li-Frameni families, suggests ...
Tópico(s): Hedgehog Signaling Pathway Studies
2012 - BioMed Central | Hereditary Cancer in Clinical Practice
Produção Nacional
Dhuliane Macêdo Damascena, Paulo Roberto Lima Falcão do Vale,
Resumo O objetivo desse estudo foi identificar tipologias da precarização do trabalho na Atenção Básica pela ótica de Druck e Franco. Estudo qualitativo, do tipo netnográfico, realizado na plataforma virtual Youtube, com vídeos brasileiros. Foram selecionados nove vídeos para análise. Foram empregadas a análise iconográfica e a análise de conteúdo temática. A pesquisa foi realizada de julho de 2018 a janeiro de 2019. Com base nos resultados, quatro categorias de análise foram identificadas: vulnerabilidade ...
Tópico(s): Occupational Health and Burnout
2020 - Fundação Oswaldo Cruz, Escola Politécnica de Saúde Joaquim Venâncio | Trabalho Educação e Saúde
Produção Nacional
Revisado por pares
Paulo Roberto Lima Falcão do Vale, Deisyane Vitória Alves, Evanilda Souza de Santana Carvalho,
ABSTRACT Objective: To understand the experiences and care practices of mothers of children with congenital Zika syndrome. Methods: A qualitative study with collection held in Feira de Santana - Bahia, between September and November 2017, from in-depth interviews and Story-Drawing with 11 family members of children, using thematic content analysis. Results: Mothers take care from experiences with health professionals and groups of mothers. They reorganize themselves in order to optimize time, streamline ...
Tópico(s): Child Nutrition and Water Access
2020 - UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL | Revista gaúcha de enfermagem
Produção Nacional
Revisado por pares
Paulo Roberto Lima Falcão do Vale, Sheila Santa Bárbara Cerqueira, Hudson P. Santos, Beth Black, Evanilda Souza de Santana Carvalho,
Abstract The rapidly increasing number of cases of Zika virus and limited understanding of its congenital sequelae (e.g., microcephaly) led to stories of fear and uncertainty across social media and other mass communication networks. In this study, we used techniques generic to netnography, a form of ethnography, using Internet‐based computer‐mediated communications as a source of data to understand the experience and perceptions of families with infants diagnosed with Zika‐related microcephaly. ...
Tópico(s): Microfinance and Financial Inclusion
2018 - Wiley | Nursing Inquiry
Produção Nacional
Revisado por pares
Karynne Grutter Lopes, Eline Coan Romagna, Daniel Sant’Anna da Silva, Michelle da Costa Tavares Bezerra, Paulo Roberto Falcão Leal, Jorge Eduardo da Silva Soares Pinto, Eliete Bouskela, Maria das Graças Coelho de Souza, Luiz Guilherme Kraemer‐Aguiar,
Bariatric surgery promotes expressive weight loss, improving the metabolic and inflammatory profiles. The behavior of these indicators in bariatric patients with weight recidivism is unknown. We aimed to investigate both profiles in bariatric patients with high ratio of weight regain (RWR), comparing them with nonsurgical patients with obesity. Forty patients with obesity subjected to Roux-en-Y gastric bypass (RYGB) with high RWR composed the bariatric group, and 40 controls matched for BMI, age, ...
Tópico(s): Body Contouring and Surgery
2022 - Springer Science+Business Media | Obesity Surgery
Produção Nacional
Revisado por pares
Milena Nascimento Guirra Saturnino, Tamires Pereira dos Santos, Paulo Roberto Lima Falcão do Vale, Maria Geralda Gomes Aguiar,
Resumo As concepções de saúde, doença, cuidado e de práticas de cuidado em unidades familiares de feirantes em Feira de Santana – BA constituem o objeto do estudo com o objetivo de compreender as relações entre as concepções de saúde, doença e os modos de ver suas práticas de cuidado. Realizou-se pesquisa exploratória na abordagem qualitativa, com 16 trabalhadores feirantes, mediante entrevista semiestruturada. O “corpus” foi submetido à análise de conteúdo temática. As concepções sobre saúde, doença ...
Tópico(s): Global Public Health Policies and Epidemiology
2019 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Pricila Oliveira de Araújo, Isabela Machado Sampaio Costa Soares, Paulo Roberto Lima Falcão do Vale, Anderson Reis de Sousa, Elena Casado Aparício, Evanilda Souza de Santana Carvalho,
Objetivo: mapear las expresiones y medidas para combatir el edadismo contra las personas mayores en los servicios de salud. Método: revisión de alcance de estudios primarios en inglés, español y portugués, sin delimitación temporal, recopilados de 14 bases de datos. Dos revisores independientes realizaron de forma ciega la selección de títulos, resúmenes y texto completo, el corpus estuvo compuesto por 41 artículos. La extracción de datos se realizó por pares. Los datos se presentaron en resúmenes ...
Tópico(s): Aging, Health, and Disability
2023 - UNIVERSIDADE DE SÃO PAULO | Revista Latino-Americana de Enfermagem
Produção Nacional
Revisado por pares
Murilo Carrazedo Marques da Costa Filho, Roberto Pessoa de Queiroz Falcão, Paulo Cesar de Mendonça Motta,
Purpose Low-income consumers (LICs) have gained more attention from marketers after Prahalad and Hart (2004) called attention to untapped opportunities among the world’s poorest. Once neglected and seen as price-driven, more recent research has depicted LICs as brand-conscious consumers who are willing to pay a premium for quality. However, because LICs must balance their tight budgets with aspirations for branded items, this perspective may be too optimistic. To address this issue, the purpose of ...
Tópico(s): Environmental Sustainability in Business
2020 - Emerald Publishing Limited | Qualitative Market Research An International Journal
Produção Nacional
Revisado por pares
Evanilda Souza de Santana Carvalho, Paulo Roberto Lima Falcão do Vale, Karina Araújo Pinto, Sílvia Lúcia Ferreira,
to characterize the content of Youtube™ videos related to nursing professionals during the COVID-19 pandemic.a qualitative study that examined 47 videos on Youtube™ posted between 11/03 and 11/04 2020, which were subjected to thematic analysis.four categories emerged: "the role of nurses in care production during the pandemic", which addresses the management of services and individual care; "Overview of the pandemic from the perspective of nurses in different countries", presenting experiences and ...
Tópico(s): COVID-19 Pandemic Impacts
2021 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem
Produção Nacional
Revisado por pares
Jacqueline Araújo, Lucas AC Brandão, Rafael Lima Guimarães, Sérgio Santos, Elcy A. Falcão, Michele Milanese, Ludovica Segat, Paulo Roberto Eleutério de Souza, José Luiz de Lima-Filho, Sérgio Crovella,
Pediatric DiabetesVolume 9, Issue 4pt1 p. 272-276 Prevalence of autoimmune thyroid disease and thyroid dysfunction in young Brazilian patients with type 1 diabetes Jacqueline Araujo, Corresponding Author Jacqueline Araujo Pediatric Endocrinology Unit of Clinical Hospital, Federal University of Pernambuco, Recife, Pernambuco, Brazil Maternal and Children Institute of Pernambuco, Recife, Pernambuco, BrazilJacqueline AraujoRua Dhália, No 304, Apartment 902Boa ViagemRecifePernambuco 51020-290Brazil. ...
Tópico(s): Pancreatic function and diabetes
2008 - Wiley | Pediatric Diabetes
Produção Nacional
Revisado por pares
Paulo Roberto Lima Falcão do Vale, Pricila Oliveira de Araújo, Sarah Senna dos Santos Cardoso, Hudson P. Santos, Rosely Cabral de Carvalho, Evanilda Souza de Santana Carvalho,
to evidence and analyze the health needs of mothers of children with Congenital Zika Syndrome.a total of 44 articles published between October/2015 and March/2021 on PubMed, LILACS, Scopus, Web of Science and Science Direct were included. The RTI bank and CASP score were applied to classify the methodological quality of the studies. Reflective content analysis and Cecílio and Matsumoto's taxonomy were used for analysis. Visual map was used as a technique for presenting the results.mothers need access ...
Tópico(s): Child Nutrition and Water Access
2022 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem
Produção Nacional
Revisado por pares
Jacqueline Araújo, Lucas André Cavalcanti Brandão, Rafael Lima Guimarães, Sérgio Santos, Elcy A. Falcão, Michele Milanese, Ludovica Segat, Paulo Roberto Eleutério de Souza, José Luiz de Lima-Filho, Sérgio Crovella,
Mannose-binding lectin is an important constituent of the innate immune system, the serum levels of which are greatly affected by polymorphisms of the MBL2 gene: three polymorphisms in exon 1, as well as nucleotide variations in the promoter region of the gene, have been associated with protein deficiency and some infectious and autoimmune disease. The aim of this study was to investigate a possible association between MBL2 gene polymorphisms in patients who have developed type 1 diabetes during ...
Tópico(s): Diabetes and associated disorders
2007 - Elsevier BV | Human Immunology
Produção Nacional
Revisado por pares
Camila Fernandes, Carlos W. Wanderley, Camila Meireles Souza Silva, Heitor Amorim Muniz, Maraiza Alves Teixeira, Nathália Ribeiro Pinho Souza, André George Ferreira Cândido, Renata Brito Falcão, Marcellus Henrique Loiola Ponte de Souza, Paulo Roberto Carvalho de Almeida, Lília Maria Carneiro Câmara, Roberto César Pereira Lima‐Júnior,
Intestinal mucositis (IM) is a common side effect of irinotecan-based chemotherapy. The involvement of inflammatory mediators, such as TNF-α, IL1-β, IL-18 and IL-33, has been demonstrated. However, the role of adaptive immune system cells, whose activation is partially regulated by these cytokines, is yet unknown. Thus, we investigated the role of regulatory T cells (Tregs) in irinotecan-induced IM. C57BL/6 mice were injected with saline or irinotecan (75mgkg-1, i.p.), once a day for 4days, and euthanized ...
Tópico(s): Cancer therapeutics and mechanisms
2018 - Elsevier BV | European Journal of Pharmaceutical Sciences
Produção Nacional
Revisado por pares
Pricila Oliveira de Araújo, Isabela Machado Sampaio Costa Soares, Paulo Roberto Lima Falcão do Vale, Anderson Reis de Sousa, Elena Casado Aparício, Evanilda Souza de Santana Carvalho,
Objective: to map the expressions of ageism directed to older adults in health services and the respective coping measures. Method: a scoping review of primary studies in English, Spanish and Portuguese, without time delimitation and collected from 14 databases. Selection of the titles, abstracts and full text was in charge of two independent and blinded reviewers, totaling a corpus comprised by 41 articles. Data extraction was performed by pairs. The data were presented in narrative summaries and ...
Tópico(s): Retirement, Disability, and Employment
2023 - UNIVERSIDADE DE SÃO PAULO | Revista Latino-Americana de Enfermagem
Produção Nacional
Aline Macedo Carvalho Freitas, Josele de Farias Rodrigues Santa Barbara, Paulo Roberto Lima Falcão do Vale, Silas Santos Carvalho, Letícia Falcão de Carvalho, Givanildo da Silva Nery,
Objetivo: compreender as percepções dos estudantes de enfermagem relacionada à Qualidade de Vida (QV) durante a trajetória acadêmica em uma Universidade Pública Federal. Método: estudo exploratório, qualitativo, realizado com 14 estudantes de uma Universidade Pública Federal, entre agosto e outubro de 2012. Os instrumentos de coleta de dados foram a entrevista semiestruturada e o diário de campo, com posterior análise de conteúdo. Resultados: Emergiram duas categorias: “A universidade... Entre promotora ...
Tópico(s): Health, Nursing, Elderly Care
2017 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Revista de Enfermagem da UFSM
Produção Nacional
Revisado por pares
Paulo Roberto Lima Falcão do Vale, Diego Rangel dos Anjos Prata, Maricarla Barbosa Cordeiro, Camila Oliveira Araújo, Rebeca Valentim Leite, Ângela Cristina Fagundes Góes,
O Hiperdia refere-se ao conjunto de ações voltadas para o cuidado integral a sujeitos com hipertensão arterial sistêmica e diabetes melito. Este estudo tem como objetivo descrever as estratégias de intervenção com vistas a fortalecer a longitudinalidade do cuidado aos usuários deste Programa em uma Unidade de Saúde da Família do município de Lauro de Freitas, no estado da Bahia, no Brasil. As estratégias foram propostas por residentes em saúde da família e trabalhadores de saúde, no período de outubro ...
Tópico(s): Healthcare Regulation
2020 - | Revista de APS
Produção Nacional
Revisado por pares
Meire dos Santos Falcão de Lima, Roberto Afonso da Silva, Milena Fernandes da Silva, Paulo A.B. da Silva, Romero Marcos Pedrosa Brandão Costa, J. A. Teixeira, Ana Lúcia Figueiredo Porto, Maria Taciana Holanda Cavalcanti,
Fermented milks are a source of bioactive peptides and may be considered as functional foods. Among these, sheep's milk fermented with kefir has not been widely studied and its most relevant properties need to be more thoroughly characterized. This research study is set out to investigate and evaluate the antioxidant and antimicrobial properties of peptides from fermented sheep's milk in Brazil when produced by using kefir. For this, the chemical and microbiological composition of the sheep's milk ...
Tópico(s): Probiotics and Fermented Foods
2017 - Springer Science+Business Media | Probiotics and Antimicrobial Proteins
Produção Nacional
Revisado por pares
Federico Costa, Manoel Sarno, Ricardo Khouri, Bruno de Paula Freitas, Isadora Cristina de Siqueira, Guilherme S. Ribeiro, Hugo Ribeiro, Gúbio Soares Campos, Luíz Carlos Júnior Alcântara, Mitermayer Galvão dos Reis, Scott C. Weaver, Nikos Vasilakis, Albert I. Ko, Antonio R.P. de Almeida,
... Gonçalo Moniz, Fundação Oswaldo Cruz/MS, Rua Waldemar Falcão, 121, Candeal, Salvador, Bahia 40296-710, Brazil.Dr. de Paula Frietas: Hospital Geral Roberto Santos, Secretaria da Saúde do Estado da Bahia, Av Paulo VI, 2240, Apt. 1004, Pituba, Salvador, Bahia 41810-001, Brazil.Dr. Siqueira: Centro de Pesquisas Gonçalo Moniz, Funda, R. Waldemar Falcao, 121, Salvador, Bahia 40296-710, Brazil.Dr. G. ...
Tópico(s): Dengue and Mosquito Control Research
2016 - American College of Physicians | Annals of Internal Medicine
Produção Nacional
Revisado por pares
Adriana Sayuri Iwashita, João Paulo Papa, André Nunes de Souza, Alexandre X. Falcão, Roberto Lotufo, Viviane Maia Barreto de Oliveira, Victor Hugo C. de Albuquerque, João Manuel R. S. Tavares,
In general, pattern recognition techniques require a high computational burden for learning the discriminating functions that are responsible to separate samples from distinct classes. As such, there are several studies that make effort to employ machine learning algorithms in the context of "big data" classification problems. The research on this area ranges from Graphics Processing Units-based implementations to mathematical optimizations, being the main drawback of the former approaches to be ...
Tópico(s): Metaheuristic Optimization Algorithms Research
2014 - Elsevier BV | Pattern Recognition Letters
Produção Nacional
Revisado por pares
Daniel Cordeiro Gurgel, Deysi Viviana Tenazoa Wong, Alessandro Maia Bandeira, Jorge Fernando Bessa Pereira, Jedson Vieira Gomes-Filho, Ana Carolina Pereira, Paulo Goberlanio Barros Silva, Fabio Távora, Anamaria Falcão Pereira, Roberto César Pereira Lima‐Júnior, Paulo Roberto Carvalho de Almeida,
Triple-negative breast cancer (TNBC) is a subtype of cancer, which tests negative for estrogen receptors, progesterone receptors, and lacks overexpression of the human epidermal growth factor 2 (C-erbB2, HER2/neu) gene. The expression of chemokines and their receptors, including CCR7, has been described in several types of cancer, contributing to tumor progression. This study investigated the association between the membrane and cytoplasmic CCR7 expression and the prognosis of TNBC. Surgical paraffin ...
Tópico(s): Cell Adhesion Molecules Research
2020 - Elsevier BV | Pathology - Research and Practice
Produção Nacional
Revisado por pares
Suyiene Cordeiro Falcão, Antônio Roberto de Barros Coelho, Edvaldo Lopes de Almeida, Carlos Alberto Pessoa de Mello GALDINO,
Análise digital de imagem e planimetria são importantes instrumentos de avaliação de áreas de feridas planas submetidas a tratamento local.No processo proposto, os perímetros das áreas das feridas foram obtidos
Tópico(s): Diabetic Foot Ulcer Assessment and Management
2001 - UNIVERSIDADE DE SÃO PAULO | Brazilian Journal of Veterinary Research and Animal Science
Paulo Henrique Zanvettor, Deraldo Fernando Falcão Filho, Adson Roberto Santos Neves, Maria Jose N. Amorim, Sonia M. Medeiros, Luiz Carlos F. Laranjeiras, Jackson A. Morais, Iguaracyra Araújo, Helenemarie S. Barbosa,
Cervical cancer incidence worldwide is about 500,000 new cases per year with most of them being detected at a locally advanced stage. Many studies have shown the need to look for extra-pelvic disease when planning appropriate therapy. We performed surgical staging by laparoscopy in 43 cases of cervical cancer at stages IB2 to IVa and evaluated our initial results.Between February 2008 and May 2010, we selected 43 patients with histologically confirmed cervical cancer at stages IB2 to IVA with a ...
Tópico(s): Endometriosis Research and Treatment
2011 - Elsevier BV | Gynecologic Oncology
Kieran F. Docherty, Pardeep S. Jhund, Brian Claggett, João Pedro Ferreira, Olof Bengtsson, Silvio E. Inzucchi, Lars Køber, Mikhail Kosiborod, Anna Maria Langkilde, Felipe A. Martínez, Piotr Ponikowski, Marc S. Sabatine, Mikaela Sjöstrand, Scott D. Solomon, John J.V. McMurray, John J.V. McMurray, David L. DeMets, Silvio E. Inzucchi, Lars Køber, Mikhail Kosiborod, Anna Maria Langkilde, Felipe A. Martínez, Piotr Ponikowski, Marc S. Sabatine, Mikaela Sjöstrand, Scott D. Solomon, Mirta Díez, José Carlos Nicolau, Tzvetana Katova, Jonathan G. Howlett, Eileen O’Meara, Subodh Verma, Junbo Ge, Jan Bělohlávek, Morten Schou, Michael Böhm, Béla Merkely, Vijay Chopra, Masahumi Kitakaze, Rudolf A. de Boer, Jarosław Dróżdż, Sergey Tereshchenko, Andrej Dukát, Charlotta Ljungman, Chern‐En Chiang, Mark C. Petrie, Inder S. Anand, Akshay S. Desai, Pham Nguyễn Vinh, S. Sassone, Diego Aizenberg, María L. Talavera, Guillermo Mercau, D. Martínez, J Albisu, Alejandro Hershson, Ruben Garcia Duran, Miguel Hominal, Natalia Cluigt, F. Colombo Berra, Eduardo Perna, R. A. Ahuad Guerrero, Daniela García Brasca, Cesar Javier Zaidman, Claudio Majul, José Taborda, Hugo A Luquez, J Sala, Álvaro Sosa Liprandi, Guillermo Cursack, Oscar Montaña, A Rodríguez Fernández, M Najenson, S Nani, G Caruso, Enrique Fairman, S Pereiro Gonzalez, Lília Nigro Maia, Adamastor Humberto Pereira, P Rossi, Dalton Bertolim Précoma, Fernando Carvalho Neuenschwander, Gilmar Reis, Fabio Augusto Bronzi Guimarães, José Francisco Kerr Saraiva, Flavia Arantes, Mauro Esteves Hernandes, João Carlos de Oliveira Borges, Bruno Paolino, Eduardo Vasconcellos, Euler Roberto Fernandes Manenti, Pedro Pimentel, Paulo Leães, Salvador Rassi, Talia Falcão Dalçóquio, Tzvetana Katova, D Avramov, N Spasova, Dimitar Raev, Boryana Chompalova, Maria Milanova, Mariya Tokmakova, Nikolay Runev, Atanas Mihov, Antoni Gogov, Adriana Dincheva, Nikolay Iliev, Borislav Kolomanov, Yonka Ivanova, Kristina M. Ilieva, Dimitar Karageorgiev, I. A. Efremov, Nikolay Botushanov, S Vladeva, Christian Constance, Saul Vizel, A. Shekhar Pandey, D.C. Phaneuf, Shamir R. Mehta, Dennis Rupka, Yves Pesant, Paul Poirier, R Chehayeb, Mohan Babapulle, Eileen O’Meara, Jonathan G. Howlett, Louis Yao, Robert S. McKelvie, Subodh Verma, M Hartleib, Ram Vijayaraghavan, John Vyselaar, Fabián Azzari, Jae‐Kwan Cha, Farah Nasser-Sharif, TunZan Maung, Samer Mansour, Yaariv Khaykin, Regent Lee, Peter C.C. Fong, Hong Jiang, Xin Li, Lu Fu, Y Li, D Wang, Qiang Zhao, Yugang Dong, Yiting Zhou, Xiao-hui Lin, Jianyu Dong, X Zhang, Zhe Zheng, Wenjun Huang, Ye Gu, Jianjun Liu, X Guo, Lei Wu, Qizhu Tang, Daoquan Peng, Dong Wang, Yingzi Liang, ZAIBO LI, Z Wang, Bing Han, Chun‐Ying Wu, Jan Bělohlávek, Josef Slaby, Jindřich Špinar, Petr Hájek, Ladislav Busak, Jiri Carda, Lenka Špinarová, I. Málek, Jiří Škopek, Roman Kuchar, Eva Krčová, Otto Mayer, David J. Kucera, Morten Schou, Lars Køber, Kenneth Egstrup, JensDahlgaard Hove, Gunnar Gislason, Lars Videbæk, Michael Böhm, Ruth Nischik, Nicole Toursarkissian, Karl‐Friedrich Appel, Ekkehard Schmidt, Ingo Weigmann, Monika Kellerer, Ayham Al-Zoebi, Uta Stephan, Andreas Wilke, Sabine Genth‐Zotz, Gregor Simonis, Diethelm Tschöpe, Angelika Costard‐Jäckle, Béla Merkely, Péter Andrássy, Ebrahim Noori, Zoltán Járai, F Poór, Csaba Király, Anna Czigány, László Nagy, Ákos Motyovszki, Gabriella Masszi, Vimal Mehta, V Chopra, Ajay Naik, Milind Gadkari, Rahul Sawant, Mashhadi Mahapekar, Sunil Karna, Mukund Deshpande, Varun Bhargava, V A Kothiwale, Jaideep Menon, D Sinha, Santosh Kumar Sinha, Hemant Kokane, Prashant Udgire, Manjinder S. Sandhu, M. Suzuki, Masami Nishino, Arihiro Kiyosue, Kotaro Sumii, Shu-Ichiro Suzuki, Yoshifumi Noguchi, Shinji Tanaka, Horoyuki Takase, Mehrdad Mohri, Shinichi Higashiue, Noritaka Fujimoto, Harukazu Iseki, Takehiko Kuramochi, Tadao Shibasaki, Hiroyuki Tsutsui, Yuichiro Takagi, Yuichi Katayama, Noriyuki Takeyasu, Toshihisa Anzai, H Nagashima, Akira Kimura, Takatoshi Kakuta, Takuya Hashimoto, Hiroshi Sugino, Kazuyoshi Saito, Shitoshi Hiroi, Hajime Kamiya, Kazuki Fukui, Satoshi Matsuoka, Kazunori Moritani, Yoshiaki Tomobuchi, Yoshiki Hata, Ryo Kawamura, Eijiro Hattori, Kazuteru Fujimoto, Nobunori Takahashi, Wataru Takahashi, Toshiaki Kadokami, Hideki Ueno, Shinichiro Uchikawa, Tsuyoshi Shinozaki, Yuko Onishi, Nobuyuki Komiyama, Shujiro Inoue, Yukihiko Momiyama, Yasunori Ueda, Y Komura, Tomoharu Arakawa, Hiroshi Meno, Motoaki Higuchi, Yasushi Hayashi, Kozaburo Seki, Kenichi Fujii, Ken Harada, Atsuyuki Wada, Takatoshi Kasai, Koichiro Kuwahara, Yoshinori Yasaka, Issei Uchida, Yasuo Okumura, Yosuke Hisamatsu, Tatsuya Nunohiro, Kengo Tsukahara, A. Hirohata, Masanori Asakura, Rudolf A. de Boer, Louise Bellersen, H. Swart, Björn E. Groenemeijer, S Zoet Nugteren, Cornelis de Nooijer, Peter R Nierop,
Sodium glucose cotransporter 2 inhibitors reduce morbidity and mortality in patients with heart failure and reduced ejection fraction (HFrEF). Clinicians may find estimates of the projected long-term benefits of sodium glucose cotransporter 2 inhibitors a helpful addition to clinical trial results when communicating the benefits of this class of drug to patients.To estimate the projected long-term treatment effects of dapagliflozin in patients with HFrEF over the duration of a patient's lifetime. ...
American Medical Association
Kieran F. Docherty, Pardeep S. Jhund, Olof Bengtsson, David L. DeMets, Silvio E. Inzucchi, Lars Køber, Mikhail Kosiborod, Anna Maria Langkilde, Felipe A. Martínez, Marc S. Sabatine, Mikaela Sjöstrand, Scott D. Solomon, John J.V. McMurray, Mirta Díez, Sonia A Sassone, Diego Aizenberg, María L. Talavera, Guillermo Mercau, Diego Martínez, Juan Pablo Albisu, Alejandro Hershson, Rubén GarcíaDurán, Miguel Hominal, Natalia Cluigt, Fernando ColomboBerra, Eduardo Perna, Rodolfo AhuadGuerrero, Daniela GarcíaBrasca, Cesar Javier Zaidman, Claudio Majul, José Taborda, Hugo A Luquez, Jorgelina Sala, Alvaro SosaLiprandi, Guillermo Cursack, Oscar Montaña, A Rodríguez Fernández, M Najenson, S Nani, G Caruso, Enrique Fairman, Stella PereiroGonzalez, Lília Nigro Maia, Adamastor Humberto Pereira, Paulo Roberto Ferreira ROSSI, Dalton Bertolim Précoma, Fernando Carvalho Neuenschwander, Gilmar Reis, Fabio Augusto Bronzi Guimarães, José Francisco Kerr Saraiva, Flavia Arantes, Mauro Esteves Hernandes, João Carlos de Oliveira Borges, Bruno Paolino, Eduardo Vasconcellos, Euler Roberto Fernandes Manenti, Pedro Pimentel, Paulo Leães, Salvador Rassi, Talia Falcão Dalçóquio, Tsvetana Katova, D Avramov, N Spasova, Dimitar Raev, Boryana Chompalova, Maria Milanova, Mariya Tokmakova, N. Runev, Atanas Mihov, Antoni Gogov, Adriana Dincheva, Nikolay Iliev, Borislav Kolomanov, Yuliyana Ivanova, Katya Ilieva, Dimitar Karageorgiev, Ivo Petrov, Nikolay Botushanov, S Vladeva, Christian Constance, Saul Vizel, A. Shekhar Pandey, Denis-Carl Phaneuf, Shamir R. Mehta, Dennis Rupka, Yves Pesant, Paul Poirier, R Chehayeb, Mohan Babapulle, Eileen O’Meara, Jonathan G. Howlett, Louis Yao, Robert S. McKelvie, Subodh Verma, Michael Hartleib, Ram Vijayaraghavan, John Vyselaar, Fabián Azzari, James Cha, Farah Nasser-Sharif, TunZan Maung, Samer Mansour, Yaariv Khaykin, Rina Lee, Peter C.C. Fong, Junbo Ge, Hong Jiang, Xinli Li, Lu Fu, Ying Li, Dongfang Wang, Qiang Zhao, Yugang Dong, Yimeng Zhou, Xiu-Fang Lin, Jianzeng Dong, Xiaoli Zhang, Zeqi Zheng, Wenjun Huang, Ye Gu, Jinqiu Liu, X Guo, Ling Wu, Qizhu Tang, Daoquan Peng, Wei Dong, Yingzi Liang, Daying Wang, Chun‐Ying Wu, Zhanquan Li, Xuefeng Lin, Xuelian Zhang, Zhirong Wang, Bing Han, Jan Bělohlávek, Josef Slaby, Jindřich Špinar, Petr Hájek, Ladislav Busak, Jiri Carda, Lenka Špinarová, Ivan Málek, Jiří Škopek, Roman Kuchar, Eva Krčová, Otto Mayer, Dusan Kucera, Morten Schou, Lars Køber, Kenneth Egstrup, JensDahlgaard Hove, Gunnar Gislason, Lars Videbæk, Michael Böhm, Ruth Nischik, Nicole Toursarkissian, Karl‐Friedrich Appel, Ekkehard Schmidt, Ingo Weigmann, Monika Kellerer, Ayham Al-Zoebi, Uta Stephan, Andreas Wilke, Sabine Genth‐Zotz, Gregor Simonis, Diethelm Tschöpe, Angelika Costard‐Jäckle, Mark C. Petrie, Roy S. Gardner, Andrew L. Clark, Alan G. Japp, Pardeep S. Jhund, Chim C. Lang, Stephen J Leslie, Clare Murphy, Colin J. Petrie, John Walsh, Béla Merkely, Péter Andrássy, Ebrahim Noori, Zoltán Járai, F Poór, Csaba Király, Anna Czigány, László Nagy, Ákos Motyovszki, Gabriella Masszi, Vimal Mehta, Vijay Chopra, Ajay Naik, Milind Gadkari, Rahul Sawant, Mashhadi Mahapekar, Sunil Karna, Mukund Deshpande, Varun Bhargava, V A Kothiwale, Jaideep Menon, Dhurjati Prasad Sinha, Santosh Kumar Sinha, Hemant Kokane, Prashant Udgire, Manjinder S. Sandhu, Masahiro Suzuki, Masami Nishino, Arihiro Kiyosue, Kotaro Sumii, Shu Suzuki, Yuichi Noguchi, Shinji Tanaka, Horoyuki Takase, Masahiro Mohri, Shinichi Higashiue, Noritaka Fujimoto, Harukazu Iseki, Takehiko Kuramochi, Taro Shibasaki, Hiroshi Tsutsui, Yuichiro Takagi, Satoru Sakuragi, Noriyuki Takeyasu, Masahumi Kitakaze, Chisato Izumi, Takafumi Oga, Akira Kimura, Tsunekazu Kakuta, Tetsuo Hashimoto, Hiroshi Sugino, Kozue Saito, Shitoshi Hiroi, Haruo Kamiya, Kazuki Fukui, Satoshi Matsuoka, Kazunori Moritani, Yoshiaki Tomobuchi, Yoshiki Hata, Ryo Kawamura, Eijiro Hattori, Kazuteru Fujimoto, Natsuki Takahashi, Wataru Takahashi, Toshiaki Kadokami, Hideki Ueno, Shinichiro Uchikawa, Tsuyoshi Shinozaki, Yuko Onishi, Nobuyuki Komiyama, Shujiro Inoue, Yukihiko Momiyama, Yasunori Ueda, Yasuo Komura, Ryo Hayashida, Seigo Masuda, Motoaki Higuchi, Yasushi Hayashi, Kozaburo Seki, Kenshi Fujii, Ken Harada, Atsuyuki Wada, Takatoshi Kasai, Koichiro Kuwahara, Shogo Oishi, Issei Uchida, Yasuo Okumura, Yuji Hisamatsu, Tatsuya Nunohiro, Kengo Tsukahara, Atsushi Hirohata, Masanori Asakura, Rudolf deBoer, Louise Bellersen, Henk P. Swart, Björn E. Groenemeijer, S K Zoet-Nugteren, Cornelis deNooijer, Pieter M. H. Nierop, Ramon RoblesdeMedina, Jacob vanEck, Maarten vanHessen, Jarosław Dróżdż, Paweł Miękus, R Ściborski, Beata Mikłaszewicz, Wanda Sudnik, Rafał Mariankowski, Robert Witek, Grzegorz Drelich, Ewa Mirek-Bryniarska, Sławomir Szynal, Lidia Pawłowicz, Jacek Lampart, Romuald Korzeniak, Janusz Prokopczuk, С. А. Болдуева, Yury Didenko, Nino Dzhaiani,
OBJECTIVE To determine whether the benefits of dapagliflozin in patients with heart failure and reduced ejection fraction (HFrEF) and type 2 diabetes in the Dapagliflozin And Prevention of Adverse-Outcomes in Heart Failure trial (DAPA-HF) varied by background glucose-lowering therapy (GLT). RESEARCH DESIGN AND METHODS We examined the effect of study treatment by the use or not of GLT and by GLT classes and combinations. The primary outcome was a composite of worsening heart failure (hospitalization ...
American Diabetes Association
Produção Nacional
Lívia Falcão Lima, Bruna Cristina Cardoso Martins, Francisco Roberto Pereira de Oliveira, Rafaela Michele de Andrade Cavalcante, Vanessa Pinto Magalhães, Paulo Yuri Milen Firmino, Liana Silveira Adriano, Adriano Monteiro da Silva, M.J. Flor, Eugenie Desirèe Rabelo Néri,
To describe and analyze the pharmaceutical orientation given at hospital discharge of transplant patients.This was a cross-sectional, descriptive and retrospective study that used records of orientation given by the clinical pharmacist in the inpatients unit of the Kidney and Liver Transplant Department, at Hospital Universitário Walter Cantídio, in the city of Fortaleza (CE), Brazil, from January to July, 2014. The following variables recorded at the Clinical Pharmacy Database were analyzed according ...
Tópico(s): Patient Safety and Medication Errors
2016 - Instituto Israelita de Ensino e Pesquisa Albert Einstein | Einstein (São Paulo)
Miguel Guerra, Roberto Roncon‐Albuquerque, André P. Lourenço, Inês Falcão‐Pires, Paulo Cibrão‐Coutinho, Adelino Leite‐Moreira,
The aim of the present study was to investigate how early the onset of ischaemia-induced changes in gene expression is in remote myocardium, and whether these changes would be different for left and right ventricles. Wistar rats (n=27) were randomly assigned to left coronary artery (LCA) ligation for 30 or 120 min and sham groups. Evans Blue infusion revealed antero-apical left ventricle (LV) and left intraventricular (IV) septal ischaemia (35.5+/-0.6% of LV mass). LCA ligation induced transient LV systolic ...
Tópico(s): Cardiac Fibrosis and Remodeling
2006 - Wiley | Experimental Physiology
Produção Nacional
Revisado por pares
Paulo Roberto Lima Falcão do Vale, Sílvia da Silva Santos Passos, Rosely Cabral de Carvalho, Evanilda Souza de Santana Carvalho,
To comprehend the daily rites of child-mothers with congenital Zika virus syndrome for the prevention of COVID-19 during the pandemic.Study with a qualitative-exploratory approach, in the light on the comprehensive sociology of Michel Maffesoli, carried out in WhatsApp groups of associations of families of children with the syndrome. 44 mothers answered the online questionnaire between April and May 2020. Lexical and similarity analyzes were used through IRaMuTeQ.Mothers encourage exercises for ...
Tópico(s): Global Maternal and Child Health
2021 - UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL | Revista gaúcha de enfermagem
Produção Nacional
Revisado por pares
Paulo Roberto de Araújo Porto, Eliane Brígida Morais Falcão,
Neste trabalho foram analisadas as representações sociais de um grupo de estudantes do Ensino Médio de uma escola confessional católi ca sobre a origem dos seres vivos, com destaque para o surgimento do homem e da mulher. No estudo, utilizou-se a metodologia do discurso do sujeito coletivo (DSC). Os resultados obtidos mostraram que o grupo investigado tem fortes características religiosas, mas com abertura para as explicações científicas. Seus discursos, ao revelarem influências religiosas, não indicaram ...
Tópico(s): Animal and Plant Science Education
2010 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Ensaio
Produção Nacional
Revisado por pares
Deysi Viviana Tenazoa Wong, Renata Brito Falcão Holanda, Aurilene Gomes Cajado, Alessandro Maia Bandeira, Jorge Fernando Bessa Pereira, Joice Oliveira Amorim, Clarice Sampaio Torres, Luana Maria Moura Ferreira, Marina Helena Silva Lopes, Roberta Taiane Germano de Oliveira, Anamaria Falcão Pereira, Rosane Oliveira Sant'Ana, Larissa Mont’Alverne de Arruda, Howard Lopes Ribeiro, Ronald Feitosa Pinheiro, Paulo Roberto Carvalho de Almeida, Robson Francisco Carvalho, Fábio Figueiredo Chaves, Duílio R Rocha-Filho, Fernando Q. Cunha, Roberto César Pereira Lima‐Júnior,
Severe diarrhoea, a common gastrointestinal manifestation of anticancer treatment with irinotecan, might involve single nucleotide polymorphisms (SNPs) of toll-like receptors (TLRs), described as critical bacterial sensors in the gut. Here, colorectal cancer patients carrying missense TLR4 A896G (rs4986790) or C1,196T (rs4986791) SNPs and Tlr4 knockout (Tlr4-/-) mice were given irinotecan to investigate the severity of the induced diarrhoea.Forty-six patients treated with irinotecan-based regimens had ...
Tópico(s): Neutropenia and Cancer Infections
2021 - Wiley | British Journal of Pharmacology
Produção Nacional
Revisado por pares
Wellington Caribé Santana, Alcione Assunção Correia Lima, Vinícius de Oliveira Muniz, Felipe Machuca‐Contreras, Paulo Roberto Lima Falcão do Vale, Evanilda Souza de Santana Carvalho, Anderson Reis de Sousa,
Resumo Objetivo Identificar as manifestações clínicas e as repercussões dos sintomas prolongados e das sequelas pós-COVID-19, expressos sob a forma de desconfortos, por homens nas redes sociais digitais. Métodos Estudo netnográfico realizado de julho de 2020 a janeiro de 2021 nas plataformas do Facebook ®, Instagram ® e YouTube TM, em páginas e/ou comunidades brasileiras. Os dados apreendidos foram submetidos à análise temática e interpretados sob o referencial da Teoria dos Sintomas Desagradáveis. Resultados ...
Tópico(s): COVID-19 and healthcare impacts
2023 - UNIVERSIDADE FEDERAL DE SÃO PAULO | Acta Paulista de Enfermagem